Mus musculus

0 known processes

Map3k2

mitogen-activated protein kinase kinase kinase 2

(Aliases: 9630061B06Rik,AI585793,Mekk2,Mekk2b)

Map3k2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of protein complex assembly GO:0043254 83 0.333
regulation of cellular ketone metabolic process GO:0010565 66 0.261
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.244
negative regulation of molecular function GO:0044092 258 0.229
positive regulation of cellular amine metabolic process GO:0033240 5 0.224
regulation of transferase activity GO:0051338 263 0.207
negative regulation of ripoptosome assembly involved in necroptotic process GO:1902443 3 0.187
cellular ketone metabolic process GO:0042180 84 0.174
amine metabolic process GO:0009308 45 0.168
regulation of cellular amine metabolic process GO:0033238 20 0.162
negative regulation of protein metabolic process GO:0051248 282 0.159
regulation of protein kinase activity GO:0045859 232 0.153
regulation of cellular amino acid metabolic process GO:0006521 5 0.140
immune effector process GO:0002252 321 0.140
negative regulation of phosphorylation GO:0042326 166 0.137
ras protein signal transduction GO:0007265 77 0.124
positive regulation of mapk cascade GO:0043410 170 0.114
Mouse
regulation of vesicle mediated transport GO:0060627 139 0.109
protein modification by small protein conjugation GO:0032446 187 0.108
negative regulation of endopeptidase activity GO:0010951 44 0.107
protein maturation GO:0051604 176 0.106
myeloid cell differentiation GO:0030099 233 0.106
positive regulation of protein phosphorylation GO:0001934 242 0.097
ubiquitin dependent smad protein catabolic process GO:0030579 2 0.096
rhodopsin mediated signaling pathway GO:0016056 4 0.096
regulation of kinase activity GO:0043549 249 0.095
endocytosis GO:0006897 168 0.093
negative regulation of phosphorus metabolic process GO:0010563 184 0.092
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.089
negative regulation of protein processing GO:0010955 79 0.088
positive regulation of protein modification process GO:0031401 299 0.088
lymphocyte proliferation GO:0046651 164 0.084
regulation of protein maturation GO:1903317 96 0.083
ripoptosome assembly involved in necroptotic process GO:1901026 6 0.083
regulation of lymphocyte activation GO:0051249 240 0.082
regulation of protein serine threonine kinase activity GO:0071900 157 0.081
protein modification by small protein conjugation or removal GO:0070647 207 0.080
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.080
inflammatory response GO:0006954 244 0.079
cellular amino acid metabolic process GO:0006520 103 0.077
protein polyubiquitination GO:0000209 33 0.075
regulation of secretion by cell GO:1903530 249 0.073
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 26 0.073
negative regulation of synaptic vesicle transport GO:1902804 3 0.071
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.071
canonical wnt signaling pathway GO:0060070 130 0.070
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.069
synaptic vesicle transport GO:0048489 57 0.068
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.068
cytokine production GO:0001816 319 0.067
leukocyte activation involved in immune response GO:0002366 126 0.066
blood vessel morphogenesis GO:0048514 285 0.065
response to organic cyclic compound GO:0014070 198 0.065
regulation of anatomical structure size GO:0090066 178 0.064
negative regulation of immune system process GO:0002683 209 0.063
regulation of cellular component biogenesis GO:0044087 181 0.063
nitrogen compound transport GO:0071705 271 0.063
regulation of proteolysis GO:0030162 164 0.063
regulation of hormone levels GO:0010817 211 0.063
protein localization to organelle GO:0033365 185 0.062
cellular lipid metabolic process GO:0044255 323 0.061
negative regulation of cellular protein metabolic process GO:0032269 247 0.060
regulation of hydrolase activity GO:0051336 246 0.060
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.060
alpha beta t cell activation GO:0046631 91 0.059
cell type specific apoptotic process GO:0097285 268 0.058
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.058
positive regulation of kinase activity GO:0033674 155 0.058
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.058
protein ubiquitination GO:0016567 171 0.057
carbohydrate metabolic process GO:0005975 230 0.057
regulation of multi organism process GO:0043900 111 0.057
negative regulation of phosphate metabolic process GO:0045936 184 0.057
peptidyl serine phosphorylation GO:0018105 74 0.056
t cell activation GO:0042110 289 0.056
male gamete generation GO:0048232 285 0.055
peptidyl serine modification GO:0018209 83 0.055
regulation of mapk cascade GO:0043408 248 0.055
Mouse
extrinsic apoptotic signaling pathway GO:0097191 126 0.054
negative regulation of t helper 2 cell differentiation GO:0045629 4 0.053
protein catabolic process GO:0030163 221 0.052
regulation of inflammatory response GO:0050727 147 0.052
adaptive immune response GO:0002250 155 0.052
cell activation involved in immune response GO:0002263 126 0.052
regulation of cell projection organization GO:0031344 206 0.052
regulation of t cell activation GO:0050863 170 0.051
intracellular protein transport GO:0006886 204 0.051
modification dependent macromolecule catabolic process GO:0043632 133 0.050
regulation of lymphocyte proliferation GO:0050670 117 0.050
response to growth factor GO:0070848 198 0.050
regulation of neuron differentiation GO:0045664 281 0.049
negative regulation of proteolysis GO:0045861 74 0.049
positive regulation of cell death GO:0010942 224 0.049
aromatic compound catabolic process GO:0019439 286 0.048
positive regulation of cell activation GO:0050867 158 0.048
regulation of alpha beta t cell activation GO:0046634 53 0.048
cellular macromolecule catabolic process GO:0044265 206 0.048
positive regulation of programmed cell death GO:0043068 218 0.048
regulation of defense response GO:0031347 233 0.047
cellular response to growth factor stimulus GO:0071363 197 0.047
camera type eye development GO:0043010 266 0.047
leukocyte differentiation GO:0002521 342 0.047
positive regulation of transferase activity GO:0051347 167 0.047
protein processing GO:0016485 163 0.046
defense response to bacterium GO:0042742 119 0.046
response to endoplasmic reticulum stress GO:0034976 53 0.046
embryonic placenta development GO:0001892 98 0.045
negative regulation of hydrolase activity GO:0051346 71 0.045
positive regulation of map kinase activity GO:0043406 84 0.045
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 3 0.045
negative regulation of necroptotic process GO:0060546 9 0.044
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.044
epithelial cell development GO:0002064 159 0.044
cellular response to lipid GO:0071396 145 0.044
regulation of stress activated mapk cascade GO:0032872 69 0.043
Mouse
membrane lipid metabolic process GO:0006643 53 0.043
heterocycle catabolic process GO:0046700 280 0.043
negative regulation of peptidase activity GO:0010466 46 0.043
regulation of protein processing GO:0070613 96 0.042
positive regulation of protein kinase activity GO:0045860 144 0.042
carbohydrate derivative catabolic process GO:1901136 231 0.042
wound healing GO:0042060 157 0.042
nucleoside triphosphate metabolic process GO:0009141 230 0.041
actin cytoskeleton organization GO:0030036 220 0.041
cellular response to hormone stimulus GO:0032870 150 0.041
peptidyl amino acid modification GO:0018193 336 0.041
spermatogenesis GO:0007283 284 0.041
nucleocytoplasmic transport GO:0006913 139 0.041
cellular response to dna damage stimulus GO:0006974 207 0.040
respiratory tube development GO:0030323 167 0.040
t cell anergy GO:0002870 4 0.040
response to organonitrogen compound GO:0010243 246 0.040
multicellular organism growth GO:0035264 161 0.039
renal system development GO:0072001 225 0.039
skeletal system development GO:0001501 356 0.039
positive regulation of t cell anergy GO:0002669 4 0.039
ribonucleoside triphosphate metabolic process GO:0009199 220 0.038
oxidation reduction process GO:0055114 342 0.038
nuclear transport GO:0051169 139 0.038
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.038
learning or memory GO:0007611 148 0.037
regulation of leukocyte differentiation GO:1902105 159 0.037
ion transmembrane transport GO:0034220 361 0.037
telencephalon development GO:0021537 186 0.037
regulation of secretion GO:0051046 274 0.037
sphingolipid metabolic process GO:0006665 45 0.037
cytoplasmic transport GO:0016482 234 0.036
cellular homeostasis GO:0019725 240 0.036
steroid metabolic process GO:0008202 119 0.036
muscle tissue development GO:0060537 308 0.036
regulation of establishment of protein localization GO:0070201 181 0.036
regulation of apoptotic signaling pathway GO:2001233 197 0.036
modification dependent protein catabolic process GO:0019941 133 0.035
regulation of cytokine production GO:0001817 266 0.035
spermatid development GO:0007286 108 0.035
positive regulation of lymphocyte anergy GO:0002913 4 0.035
positive regulation of canonical wnt signaling pathway GO:0090263 29 0.035
purine nucleoside triphosphate catabolic process GO:0009146 203 0.035
respiratory system development GO:0060541 190 0.034
regulation of organelle organization GO:0033043 289 0.034
regulation of neuron projection development GO:0010975 169 0.034
skin development GO:0043588 220 0.033
regulation of membrane potential GO:0042391 192 0.033
positive regulation of cell development GO:0010720 237 0.033
cellular protein catabolic process GO:0044257 155 0.033
response to inorganic substance GO:0010035 96 0.033
transmission of nerve impulse GO:0019226 76 0.033
reactive oxygen species metabolic process GO:0072593 84 0.033
regulation of protein catabolic process GO:0042176 108 0.033
endocrine system development GO:0035270 98 0.033
innate immune response GO:0045087 157 0.033
organelle assembly GO:0070925 177 0.033
negative regulation of cellular component organization GO:0051129 194 0.033
macromolecule catabolic process GO:0009057 281 0.033
epithelial tube morphogenesis GO:0060562 303 0.033
rho protein signal transduction GO:0007266 32 0.033
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.033
positive regulation of protein complex assembly GO:0031334 45 0.033
stress activated mapk cascade GO:0051403 80 0.032
Mouse
regulation of leukocyte proliferation GO:0070663 121 0.032
fat cell differentiation GO:0045444 160 0.032
ubiquitin dependent protein catabolic process GO:0006511 129 0.032
regulation of lipid metabolic process GO:0019216 118 0.032
embryonic organ morphogenesis GO:0048562 276 0.031
regulation of cell activation GO:0050865 289 0.031
positive regulation of nervous system development GO:0051962 221 0.031
negative regulation of immune effector process GO:0002698 55 0.031
negative regulation of t cell activation GO:0050868 65 0.031
purine nucleotide metabolic process GO:0006163 302 0.031
regulation of response to drug GO:2001023 2 0.031
regulation of endopeptidase activity GO:0052548 89 0.031
mesenchyme development GO:0060485 152 0.031
interleukin 8 production GO:0032637 4 0.031
synapse organization GO:0050808 125 0.030
negative regulation of necrotic cell death GO:0060547 11 0.030
positive regulation of lymphocyte activation GO:0051251 140 0.030
digestive system development GO:0055123 200 0.030
lung development GO:0030324 164 0.030
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.030
stress activated protein kinase signaling cascade GO:0031098 81 0.030
Mouse
gliogenesis GO:0042063 141 0.029
epithelial cell proliferation GO:0050673 174 0.029
regulation of cell migration GO:0030334 219 0.029
insulin secretion GO:0030073 89 0.029
regulation of neuron apoptotic process GO:0043523 122 0.029
organonitrogen compound catabolic process GO:1901565 264 0.029
ear morphogenesis GO:0042471 118 0.029
glycerolipid metabolic process GO:0046486 122 0.029
regulation of protein transport GO:0051223 163 0.029
regulation of response to biotic stimulus GO:0002831 38 0.028
acetylcholine transport GO:0015870 2 0.028
detection of stimulus GO:0051606 84 0.028
ribonucleoside catabolic process GO:0042454 206 0.028
peptide hormone secretion GO:0030072 109 0.028
ossification GO:0001503 216 0.028
proteasomal protein catabolic process GO:0010498 98 0.028
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.028
alcohol metabolic process GO:0006066 116 0.028
inhibition of cysteine type endopeptidase activity involved in apoptotic process GO:1990001 1 0.027
asymmetric stem cell division GO:0098722 3 0.027
gland development GO:0048732 330 0.027
positive regulation of wnt signaling pathway GO:0030177 45 0.027
positive regulation of cytokine production GO:0001819 174 0.027
leukocyte mediated immunity GO:0002443 174 0.027
regulation of cytoskeleton organization GO:0051493 122 0.027
glycerophospholipid metabolic process GO:0006650 71 0.027
rap protein signal transduction GO:0032486 3 0.027
negative regulation of transferase activity GO:0051348 85 0.027
organelle localization GO:0051640 179 0.027
ribose phosphate metabolic process GO:0019693 291 0.027
regulation of ion transport GO:0043269 215 0.027
apoptotic signaling pathway GO:0097190 306 0.027
muscle system process GO:0003012 141 0.026
negative regulation of defense response GO:0031348 77 0.026
spermatid differentiation GO:0048515 115 0.026
lymphocyte differentiation GO:0030098 242 0.026
regulation of cellular response to stress GO:0080135 159 0.026
Mouse
g protein coupled receptor signaling pathway GO:0007186 243 0.026
peptide secretion GO:0002790 114 0.026
organelle fission GO:0048285 170 0.026
nucleotide metabolic process GO:0009117 332 0.026
covalent chromatin modification GO:0016569 163 0.026
regulation of cellular component size GO:0032535 121 0.026
regulation of ossification GO:0030278 112 0.026
regulation of t cell anergy GO:0002667 4 0.026
negative regulation of kinase activity GO:0033673 81 0.026
regulation of rho gtpase activity GO:0032319 58 0.025
positive regulation of phospholipase c activity GO:0010863 2 0.025
organonitrogen compound biosynthetic process GO:1901566 192 0.025
peptide transport GO:0015833 133 0.025
regulation of peptidase activity GO:0052547 96 0.025
blood coagulation GO:0007596 76 0.025
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.025
leukocyte proliferation GO:0070661 172 0.025
cation transport GO:0006812 399 0.025
lipid modification GO:0030258 65 0.024
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.024
regulation of lymphocyte anergy GO:0002911 4 0.024
ameboidal type cell migration GO:0001667 128 0.024
regulation of cell cycle GO:0051726 281 0.024
myeloid leukocyte differentiation GO:0002573 119 0.024
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.024
regulation of striated muscle cell differentiation GO:0051153 81 0.024
negative regulation of neuron death GO:1901215 98 0.024
t cell proliferation GO:0042098 120 0.024
ribonucleoside triphosphate catabolic process GO:0009203 199 0.024
mitotic cell cycle GO:0000278 195 0.024
germ cell development GO:0007281 185 0.024
cytokine mediated signaling pathway GO:0019221 115 0.024
regulation of nucleotide catabolic process GO:0030811 122 0.024
cellular amine metabolic process GO:0044106 44 0.023
immune response regulating signaling pathway GO:0002764 125 0.023
multi organism reproductive behavior GO:0044705 29 0.023
cognition GO:0050890 149 0.023
lymphocyte anergy GO:0002249 4 0.023
nucleobase containing small molecule metabolic process GO:0055086 352 0.023
transmembrane transport GO:0055085 412 0.023
regulation of protein localization GO:0032880 231 0.023
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.023
retrograde transport endosome to golgi GO:0042147 2 0.023
regulation of cell motility GO:2000145 236 0.022
negative regulation of lymphocyte activation GO:0051250 91 0.022
cellular protein complex assembly GO:0043623 116 0.022
axon guidance GO:0007411 141 0.022
regulation of interleukin 8 production GO:0032677 3 0.022
amide transport GO:0042886 138 0.022
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.022
positive regulation of protein modification by small protein conjugation or removal GO:1903322 30 0.022
molting cycle GO:0042303 90 0.022
cellular component assembly involved in morphogenesis GO:0010927 139 0.022
regulation of cell adhesion GO:0030155 154 0.022
wnt signaling pathway GO:0016055 188 0.022
mapk cascade GO:0000165 281 0.022
Mouse
negative regulation of multi organism process GO:0043901 68 0.022
regulation of neuron death GO:1901214 134 0.022
mitotic cell cycle process GO:1903047 159 0.022
blood circulation GO:0008015 195 0.022
positive regulation of t cell activation GO:0050870 101 0.022
limb development GO:0060173 166 0.022
regulation of map kinase activity GO:0043405 120 0.021
response to unfolded protein GO:0006986 21 0.021
glycosyl compound catabolic process GO:1901658 206 0.021
angiogenesis GO:0001525 201 0.021
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.021
lymphocyte mediated immunity GO:0002449 139 0.021
dendrite development GO:0016358 115 0.021
cellular calcium ion homeostasis GO:0006874 119 0.021
branching morphogenesis of an epithelial tube GO:0048754 159 0.021
epidermis development GO:0008544 187 0.021
negative regulation of synapse assembly GO:0051964 3 0.021
maintenance of location GO:0051235 89 0.021
regulation of peptidyl serine phosphorylation GO:0033135 39 0.021
placenta development GO:0001890 140 0.021
purine ribonucleoside catabolic process GO:0046130 205 0.021
lymphocyte activation involved in immune response GO:0002285 93 0.021
gonad development GO:0008406 141 0.021
guanosine containing compound catabolic process GO:1901069 144 0.021
negative regulation of protein maturation GO:1903318 79 0.020
cellular response to cytokine stimulus GO:0071345 189 0.020
sensory perception of umami taste GO:0050917 4 0.020
small gtpase mediated signal transduction GO:0007264 97 0.020
regulation of t cell proliferation GO:0042129 92 0.020
actin filament organization GO:0007015 113 0.020
nuclear import GO:0051170 95 0.020
positive regulation of amine transport GO:0051954 8 0.020
stem cell development GO:0048864 219 0.020
positive regulation of epithelial cell proliferation GO:0050679 68 0.020
stem cell proliferation GO:0072089 117 0.020
histone modification GO:0016570 159 0.020
endoplasmic reticulum unfolded protein response GO:0030968 19 0.020
regulation of t cell differentiation GO:0045580 83 0.020
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.020
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.020
alpha beta t cell activation involved in immune response GO:0002287 31 0.020
pallium development GO:0021543 120 0.020
t cell differentiation GO:0030217 174 0.020
establishment of synaptic vesicle localization GO:0097480 57 0.020
cd4 positive alpha beta t cell differentiation involved in immune response GO:0002294 28 0.020
positive regulation of cell cycle GO:0045787 92 0.020
heart morphogenesis GO:0003007 178 0.019
regulation of actin polymerization or depolymerization GO:0008064 45 0.019
regulation of jnk cascade GO:0046328 62 0.019
macromolecule methylation GO:0043414 120 0.019
immune response activating signal transduction GO:0002757 116 0.019
embryonic appendage morphogenesis GO:0035113 126 0.019
actin filament polymerization GO:0030041 44 0.019
action potential GO:0001508 78 0.019
regulation of necroptotic process GO:0060544 10 0.019
asymmetric neuroblast division GO:0055059 1 0.019
fatty acid metabolic process GO:0006631 121 0.019
positive regulation of immune effector process GO:0002699 107 0.019
regulation of voltage gated calcium channel activity GO:1901385 4 0.019
regulation of lymphocyte differentiation GO:0045619 107 0.019
gtp metabolic process GO:0046039 144 0.019
cd4 positive alpha beta t cell activation GO:0035710 45 0.019
t cell activation involved in immune response GO:0002286 43 0.019
alpha beta t cell proliferation GO:0046633 21 0.019
urogenital system development GO:0001655 261 0.019
sensory perception of taste GO:0050909 18 0.019
hormone secretion GO:0046879 128 0.019
exocytosis GO:0006887 121 0.019
posttranscriptional regulation of gene expression GO:0010608 155 0.019
negative regulation of nervous system development GO:0051961 156 0.018
sensory organ morphogenesis GO:0090596 242 0.018
muscle cell differentiation GO:0042692 261 0.018
negative regulation of cell activation GO:0050866 111 0.018
sensory perception GO:0007600 245 0.018
hormone metabolic process GO:0042445 86 0.018
regulation of lymphocyte mediated immunity GO:0002706 84 0.018
protein localization to nucleus GO:0034504 121 0.018
regulation of protein ubiquitination GO:0031396 52 0.018
endomembrane system organization GO:0010256 147 0.018
inner ear morphogenesis GO:0042472 101 0.018
protein localization to endosome GO:0036010 2 0.018
negative regulation of cell migration GO:0030336 59 0.018
striated muscle cell development GO:0055002 125 0.018
alpha beta t cell differentiation GO:0046632 69 0.018
photoreceptor cell development GO:0042461 40 0.018
circulatory system process GO:0003013 197 0.018
nuclear division GO:0000280 158 0.018
regulation of body fluid levels GO:0050878 162 0.018
activation of immune response GO:0002253 138 0.018
single organism nuclear import GO:1902593 95 0.018
muscle cell development GO:0055001 133 0.018
negative regulation of synaptic vesicle exocytosis GO:2000301 3 0.018
synaptic transmission GO:0007268 329 0.018
bone development GO:0060348 120 0.018
carbohydrate derivative biosynthetic process GO:1901137 183 0.018
actin polymerization or depolymerization GO:0008154 54 0.018
regulation of wnt signaling pathway GO:0030111 123 0.018
appendage development GO:0048736 166 0.018
dna metabolic process GO:0006259 303 0.018
negative regulation of intracellular signal transduction GO:1902532 167 0.018
embryonic limb morphogenesis GO:0030326 126 0.018
positive regulation of apoptotic process GO:0043065 217 0.018
homeostasis of number of cells GO:0048872 210 0.018
phospholipid metabolic process GO:0006644 87 0.018
compound eye development GO:0048749 1 0.018
response to monosaccharide GO:0034284 67 0.018
regulation of cellular catabolic process GO:0031329 242 0.018
cellular nitrogen compound catabolic process GO:0044270 280 0.018
morphogenesis of a branching structure GO:0001763 203 0.018
positive regulation of defense response GO:0031349 124 0.018
retina development in camera type eye GO:0060041 119 0.018
protein import GO:0017038 101 0.017
sensory system development GO:0048880 3 0.017
regulation of leukocyte mediated immunity GO:0002703 104 0.017
nucleoside catabolic process GO:0009164 206 0.017
regulation of ras protein signal transduction GO:0046578 114 0.017
regulation of canonical wnt signaling pathway GO:0060828 82 0.017
hematopoietic progenitor cell differentiation GO:0002244 143 0.017
cellular response to inorganic substance GO:0071241 37 0.017
establishment of organelle localization GO:0051656 122 0.017
bmp signaling pathway GO:0030509 93 0.017
extracellular matrix organization GO:0030198 147 0.017
reactive oxygen species biosynthetic process GO:1903409 8 0.017
negative regulation of cell cycle GO:0045786 123 0.017
organic hydroxy compound metabolic process GO:1901615 203 0.017
g protein coupled acetylcholine receptor signaling pathway GO:0007213 4 0.017
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.017
regulation of tight junction assembly GO:2000810 2 0.017
glucocorticoid metabolic process GO:0008211 9 0.017
skeletal system morphogenesis GO:0048705 203 0.017
organ growth GO:0035265 117 0.017
positive regulation of cellular component biogenesis GO:0044089 94 0.017
smoothened signaling pathway GO:0007224 105 0.017
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.017
protein modification by small protein removal GO:0070646 21 0.017
protein import into nucleus GO:0006606 95 0.017
inhibition of cysteine type endopeptidase activity GO:0097340 1 0.017
positive regulation of protein ubiquitination GO:0031398 27 0.017
regulation of ripoptosome assembly involved in necroptotic process GO:1902442 3 0.017
regulation of exocytosis GO:0017157 61 0.017
hair cycle GO:0042633 90 0.017
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.017
negative regulation of t cell proliferation GO:0042130 38 0.016
acetylcholine secretion neurotransmission GO:0014055 2 0.016
positive regulation of secretion by cell GO:1903532 114 0.016
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.016
cell fate commitment GO:0045165 210 0.016
regulated secretory pathway GO:0045055 32 0.016
mammary gland epithelium development GO:0061180 65 0.016
ceramide metabolic process GO:0006672 31 0.016
forebrain development GO:0030900 302 0.016
organic hydroxy compound transport GO:0015850 93 0.016
negative regulation of chemokine production GO:0032682 4 0.016
positive regulation of stem cell proliferation GO:2000648 59 0.016
directional locomotion GO:0033058 3 0.016
cell adhesion GO:0007155 329 0.016
negative regulation of hormone biosynthetic process GO:0032353 4 0.016
feeding behavior GO:0007631 62 0.016
nephrogenic mesenchyme development GO:0072076 3 0.016
cellular ion homeostasis GO:0006873 165 0.016
neurotransmitter transport GO:0006836 76 0.016
digestive tract development GO:0048565 190 0.016
defecation GO:0030421 1 0.016
acetate ester transport GO:1901374 2 0.016
hindbrain development GO:0030902 128 0.016
regulation of purine nucleotide catabolic process GO:0033121 122 0.016
regulation of binding GO:0051098 111 0.016
regulation of cysteine type endopeptidase activity GO:2000116 65 0.015
cell substrate adhesion GO:0031589 130 0.015
cerebellum development GO:0021549 77 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.015
activation of mapk activity GO:0000187 59 0.015
regulation of epithelial cell proliferation GO:0050678 141 0.015
regulation of muscle tissue development GO:1901861 97 0.015
regulation of hormone secretion GO:0046883 88 0.015
neuron death GO:0070997 154 0.015
multicellular organismal signaling GO:0035637 91 0.015
cellular metal ion homeostasis GO:0006875 151 0.015
positive regulation of cellular catabolic process GO:0031331 148 0.015
regulation of actin filament based process GO:0032970 99 0.015
lipid localization GO:0010876 126 0.015
purine nucleoside triphosphate metabolic process GO:0009144 226 0.015
t helper cell differentiation GO:0042093 28 0.015
guanosine containing compound metabolic process GO:1901068 144 0.015
neuron apoptotic process GO:0051402 142 0.015
liver development GO:0001889 66 0.015
negative regulation of cell proliferation GO:0008285 296 0.015
regulation of feeding behavior GO:0060259 3 0.015
glycosyl compound metabolic process GO:1901657 246 0.015
negative regulation of ion transport GO:0043271 28 0.015
b cell activation involved in immune response GO:0002312 50 0.015
purine containing compound catabolic process GO:0072523 213 0.015
myotube differentiation GO:0014902 105 0.015
protein polymerization GO:0051258 57 0.015
ear development GO:0043583 200 0.015
purine ribonucleotide catabolic process GO:0009154 208 0.015
nucleoside triphosphate catabolic process GO:0009143 205 0.015

Map3k2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.019
disease of anatomical entity DOID:7 0 0.018
nervous system disease DOID:863 0 0.018
bone disease DOID:0080001 0 0.016
musculoskeletal system disease DOID:17 0 0.016
connective tissue disease DOID:65 0 0.016