|
|
mapk cascade
|
GO:0000165 |
281 |
0.786
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.695
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.594
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.548
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
163 |
0.471
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.460
|
|
|
|
negative regulation of blood vessel endothelial cell migration
|
GO:0043537 |
3 |
0.432
|
|
|
|
histone modification
|
GO:0016570 |
159 |
0.426
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.385
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.366
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.337
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.323
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.296
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.295
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
84 |
0.289
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.288
|
|
|
|
histone acetylation
|
GO:0016573 |
41 |
0.287
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.286
|
|
|
|
chromatin organization
|
GO:0006325 |
206 |
0.286
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.285
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.259
|
|
|
|
interleukin 8 production
|
GO:0032637 |
4 |
0.248
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.246
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.244
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.234
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.225
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
40 |
0.221
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.219
|
|
|
|
negative regulation of endothelial cell migration
|
GO:0010596 |
4 |
0.213
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.212
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.200
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.195
|
|
|
|
regulation of protein processing
|
GO:0070613 |
96 |
0.187
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.180
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.177
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.176
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.172
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.166
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.164
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.163
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.161
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.159
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.158
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.156
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.156
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.152
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.151
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.146
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.145
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.144
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.142
|
|
|
|
regulation of cell migration involved in sprouting angiogenesis
|
GO:0090049 |
4 |
0.142
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.141
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.138
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.138
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.137
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.136
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.134
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.132
|
|
|
|
protein acylation
|
GO:0043543 |
64 |
0.131
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
71 |
0.130
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.128
|
|
|
|
lung development
|
GO:0030324 |
164 |
0.128
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.127
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.126
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.124
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.116
|
|
|
|
chromatin modification
|
GO:0016568 |
187 |
0.115
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.114
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.113
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.113
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.111
|
|
|
|
regulation of response to cytokine stimulus
|
GO:0060759 |
23 |
0.111
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.110
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.110
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
96 |
0.109
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
77 |
0.108
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.108
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.104
|
|
|
|
regulation of interleukin 8 production
|
GO:0032677 |
3 |
0.104
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.103
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.103
|
|
|
|
internal protein amino acid acetylation
|
GO:0006475 |
42 |
0.103
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.101
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.100
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.100
|
|
|
|
gastrulation
|
GO:0007369 |
116 |
0.098
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
62 |
0.098
|
|
|
|
activation of mapk activity
|
GO:0000187 |
59 |
0.098
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.098
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.097
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.096
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.096
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
74 |
0.096
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
79 |
0.093
|
|
|
|
regulation of chromatin modification
|
GO:1903308 |
57 |
0.091
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
74 |
0.090
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.090
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.089
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.088
|
|
|
|
regulation of embryonic development
|
GO:0045995 |
71 |
0.088
|
|
|
|
negative regulation of interleukin 8 production
|
GO:0032717 |
1 |
0.084
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.083
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
147 |
0.083
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.082
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.081
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.081
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.079
|
|
|
|
toll like receptor signaling pathway
|
GO:0002224 |
38 |
0.079
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.078
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.078
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.078
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.078
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.077
|
|
|
|
macromolecule methylation
|
GO:0043414 |
120 |
0.076
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.075
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.075
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.075
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.075
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.075
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.074
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.073
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.072
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.072
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.072
|
|
|
|
regulation of histone modification
|
GO:0031056 |
56 |
0.072
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
44 |
0.072
|
|
|
|
tissue migration
|
GO:0090130 |
68 |
0.071
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.071
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
155 |
0.071
|
|
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
67 |
0.070
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.070
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
46 |
0.070
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.069
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.069
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
129 |
0.068
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
122 |
0.066
|
|
|
|
negative regulation of nf kappab transcription factor activity
|
GO:0032088 |
15 |
0.066
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.066
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.066
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.065
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.065
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.064
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.064
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.063
|
|
|
|
epithelium migration
|
GO:0090132 |
63 |
0.063
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.063
|
|
|
|
cell junction organization
|
GO:0034330 |
77 |
0.062
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.062
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.062
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.062
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.061
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.061
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.061
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.060
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
68 |
0.060
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.060
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.059
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.059
|
|
|
|
regulation of toll like receptor signaling pathway
|
GO:0034121 |
20 |
0.059
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.058
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.058
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.057
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.057
|
|
|
|
endothelial cell migration
|
GO:0043542 |
44 |
0.057
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.057
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
45 |
0.056
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.056
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
64 |
0.056
|
|
|
|
striated muscle cell development
|
GO:0055002 |
125 |
0.056
|
|
|
|
response to oxidative stress
|
GO:0006979 |
123 |
0.056
|
|
|
|
epithelial cell migration
|
GO:0010631 |
63 |
0.055
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.055
|
|
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.055
|
|
|
|
cell cell junction organization
|
GO:0045216 |
72 |
0.054
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.054
|
|
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.053
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.053
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.053
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.052
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.052
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.052
|
|
|
|
blood vessel endothelial cell migration
|
GO:0043534 |
23 |
0.052
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.052
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.052
|
|
|
|
t cell receptor signaling pathway
|
GO:0050852 |
46 |
0.052
|
|
|
|
organelle fission
|
GO:0048285 |
170 |
0.051
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.051
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.051
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.051
|
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
42 |
0.050
|
|
|
|
peptidyl lysine acetylation
|
GO:0018394 |
45 |
0.050
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.050
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.049
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.049
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.049
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.049
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.049
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.048
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.048
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.048
|
|
|
|
positive regulation of creb transcription factor activity
|
GO:0032793 |
4 |
0.048
|
|
|
|
regulation of endothelial cell chemotaxis
|
GO:2001026 |
1 |
0.047
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.047
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.047
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.047
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.046
|
|
|
|
respiratory system development
|
GO:0060541 |
190 |
0.046
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.046
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
83 |
0.046
|
|
|
|
actin filament organization
|
GO:0007015 |
113 |
0.045
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
83 |
0.045
|
|
|
|
regulation of striated muscle cell differentiation
|
GO:0051153 |
81 |
0.045
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.045
|
|
|
|
molting cycle
|
GO:0042303 |
90 |
0.045
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.045
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.044
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.043
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.043
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.043
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.043
|
|
|
|
methylation
|
GO:0032259 |
134 |
0.043
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.042
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.042
|
|
|
|
mesodermal cell migration
|
GO:0008078 |
4 |
0.042
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
133 |
0.042
|
|
|
|
rac protein signal transduction
|
GO:0016601 |
13 |
0.042
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.042
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.041
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
89 |
0.041
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.041
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.041
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
55 |
0.041
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
61 |
0.041
|
Human |
|
|
blood circulation
|
GO:0008015 |
195 |
0.041
|
|
|
|
activation of nf kappab inducing kinase activity
|
GO:0007250 |
4 |
0.041
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.040
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.039
|
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.039
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.039
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.039
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.039
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.039
|
|
|
|
myotube differentiation
|
GO:0014902 |
105 |
0.039
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
83 |
0.039
|
|
|
|
osteoclast differentiation
|
GO:0030316 |
62 |
0.039
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.039
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.038
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.038
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.038
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
266 |
0.038
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.038
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.037
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.037
|
|
|
|
negative regulation of phagocytosis
|
GO:0050765 |
4 |
0.037
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.037
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
71 |
0.037
|
|
|
|
negative regulation of chemokine production
|
GO:0032682 |
4 |
0.037
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.036
|
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
55 |
0.036
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.036
|
|
|
|
regulation of blood vessel endothelial cell migration
|
GO:0043535 |
12 |
0.036
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.036
|
|
|
|
lamellipodium organization
|
GO:0097581 |
29 |
0.035
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
65 |
0.035
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.035
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.035
|
|
|
|
negative regulation of cysteine type endopeptidase activity
|
GO:2000117 |
22 |
0.035
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
59 |
0.035
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
96 |
0.035
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.035
|
|
|
|
cytokine metabolic process
|
GO:0042107 |
71 |
0.034
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.034
|
|
|
|
asymmetric neuroblast division
|
GO:0055059 |
1 |
0.034
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.034
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.034
|
|
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.034
|
|
|
|
asymmetric stem cell division
|
GO:0098722 |
3 |
0.034
|
|
|
|
negative regulation of response to cytokine stimulus
|
GO:0060761 |
9 |
0.033
|
|
|
|
histone h3 acetylation
|
GO:0043966 |
14 |
0.033
|
|
|
|
myeloid dendritic cell activation
|
GO:0001773 |
25 |
0.033
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.033
|
|
|
|
negative regulation of toll like receptor signaling pathway
|
GO:0034122 |
14 |
0.033
|
|
|
|
regulation of chromatin organization
|
GO:1902275 |
57 |
0.032
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.032
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.032
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
88 |
0.032
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.032
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
48 |
0.032
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
126 |
0.031
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.031
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.031
|
|
|
|
platelet derived growth factor receptor signaling pathway
|
GO:0048008 |
32 |
0.031
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
123 |
0.031
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
113 |
0.031
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.031
|
|
|
|
gonad development
|
GO:0008406 |
141 |
0.030
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.030
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
69 |
0.030
|
|
|
|
skeletal system morphogenesis
|
GO:0048705 |
203 |
0.030
|
|
|
|
photoreceptor cell morphogenesis
|
GO:0008594 |
3 |
0.030
|
|
|
|
actin filament based movement
|
GO:0030048 |
23 |
0.030
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.029
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.029
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.029
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.029
|
|
|
|
negative regulation of cell adhesion
|
GO:0007162 |
45 |
0.029
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
98 |
0.029
|
|
|
|
defense response to virus
|
GO:0051607 |
68 |
0.029
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.028
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.028
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.028
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.028
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.028
|
|
|
|
regulation of osteoclast differentiation
|
GO:0045670 |
36 |
0.028
|
|
|
|
regulation of ossification
|
GO:0030278 |
112 |
0.028
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.028
|
|
|
|
gtp metabolic process
|
GO:0046039 |
144 |
0.028
|
|
|
|
dephosphorylation
|
GO:0016311 |
129 |
0.028
|
|
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.027
|
|
|
|
regulation of erythrocyte differentiation
|
GO:0045646 |
23 |
0.027
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
58 |
0.027
|
|
|
|
activation of innate immune response
|
GO:0002218 |
56 |
0.027
|
|
|
|
regulation of chemokine production
|
GO:0032642 |
30 |
0.027
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
65 |
0.027
|
|
|
|
midgut development
|
GO:0007494 |
4 |
0.027
|
|
|
|
plasma membrane organization
|
GO:0007009 |
90 |
0.027
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.027
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
88 |
0.027
|
|
|
|
actin filament polymerization
|
GO:0030041 |
44 |
0.027
|
|
|
|
embryonic limb morphogenesis
|
GO:0030326 |
126 |
0.026
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.026
|
Human |
|
|
stem cell maintenance
|
GO:0019827 |
130 |
0.026
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.026
|
|
|
|
glycerophospholipid metabolic process
|
GO:0006650 |
71 |
0.026
|
|
|
|
chemokine production
|
GO:0032602 |
34 |
0.026
|
|
|
|
epithelial cell morphogenesis
|
GO:0003382 |
41 |
0.026
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.026
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.026
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
76 |
0.026
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
108 |
0.026
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.026
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
133 |
0.025
|
|
|
|
jnk cascade
|
GO:0007254 |
72 |
0.025
|
|
|
|
lung alveolus development
|
GO:0048286 |
45 |
0.025
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
90 |
0.025
|
|
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
47 |
0.025
|
|
|
|
mitotic cytokinesis
|
GO:0000281 |
4 |
0.025
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.025
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.025
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
48 |
0.025
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
35 |
0.025
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
116 |
0.024
|
|
|
|
regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001239 |
26 |
0.024
|
|
|
|
positive regulation of myeloid leukocyte differentiation
|
GO:0002763 |
26 |
0.024
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
85 |
0.024
|
|
|
|
regulation of endothelial cell migration
|
GO:0010594 |
22 |
0.024
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
58 |
0.024
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
122 |
0.024
|
|
|
|
regulation of cell projection assembly
|
GO:0060491 |
38 |
0.024
|
|
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
69 |
0.023
|
|
|
|
cell growth
|
GO:0016049 |
130 |
0.023
|
|
|
|
cellular response to inorganic substance
|
GO:0071241 |
37 |
0.023
|
|
|
|
renal system development
|
GO:0072001 |
225 |
0.023
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.023
|
|
|
|
blood coagulation
|
GO:0007596 |
76 |
0.023
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.023
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.023
|
|
|
|
immunoglobulin production
|
GO:0002377 |
73 |
0.023
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
91 |
0.023
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.023
|
|
|
|
purine nucleoside monophosphate metabolic process
|
GO:0009126 |
81 |
0.023
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.023
|
|
|
|
regulation of hippo signaling
|
GO:0035330 |
1 |
0.023
|
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
59 |
0.023
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.023
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.022
|
|
|
|
myeloid dendritic cell differentiation
|
GO:0043011 |
16 |
0.022
|
|
|
|
synapse organization
|
GO:0050808 |
125 |
0.022
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
85 |
0.022
|
|
|
|
response to reactive oxygen species
|
GO:0000302 |
56 |
0.022
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.022
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
81 |
0.022
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.022
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
85 |
0.022
|
|
|
|
positive regulation of adaptive immune response
|
GO:0002821 |
61 |
0.022
|
|
|
|
protein polyubiquitination
|
GO:0000209 |
33 |
0.022
|
|
|
|
regulation of phospholipase c activity
|
GO:1900274 |
3 |
0.022
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.022
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
87 |
0.022
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.022
|
|
|
|
female meiosis chromosome segregation
|
GO:0016321 |
1 |
0.022
|
|
|
|
positive regulation of osteoclast differentiation
|
GO:0045672 |
15 |
0.022
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.022
|
|
|
|
skeletal muscle fiber development
|
GO:0048741 |
58 |
0.022
|
|
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.022
|
|
|
|
interleukin 6 production
|
GO:0032635 |
58 |
0.021
|
|
|
|
cell maturation
|
GO:0048469 |
127 |
0.021
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001240 |
16 |
0.021
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
88 |
0.021
|
|
|
|
protein localization to membrane
|
GO:0072657 |
108 |
0.021
|
|
|
|
regulation of interleukin 2 production
|
GO:0032663 |
28 |
0.021
|
|
|
|
positive regulation of chromosome organization
|
GO:2001252 |
33 |
0.021
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
62 |
0.021
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.021
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.021
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.021
|
|
|
|
positive regulation of myeloid cell differentiation
|
GO:0045639 |
43 |
0.021
|
|
|
|
interferon gamma production
|
GO:0032609 |
67 |
0.021
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.021
|
|
|
|
interleukin 1 mediated signaling pathway
|
GO:0070498 |
4 |
0.021
|
|
|
|
adherens junction assembly
|
GO:0034333 |
22 |
0.021
|
|
|
|
cellularization
|
GO:0007349 |
1 |
0.021
|
|
|
|
regulation of organ morphogenesis
|
GO:2000027 |
144 |
0.021
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.021
|
|
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
53 |
0.021
|
|
|
|
liver development
|
GO:0001889 |
66 |
0.021
|
|
|
|
atp metabolic process
|
GO:0046034 |
75 |
0.020
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.020
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.020
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
122 |
0.020
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
46 |
0.020
|
|
|
|
negative regulation of cytokine biosynthetic process
|
GO:0042036 |
13 |
0.020
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
179 |
0.020
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.020
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
79 |
0.020
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.020
|
|
|
|
pigmentation
|
GO:0043473 |
71 |
0.020
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.020
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
52 |
0.020
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
143 |
0.020
|
|
|
|
regulation of cell shape
|
GO:0008360 |
39 |
0.020
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.020
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
88 |
0.020
|
|
|
|
multi multicellular organism process
|
GO:0044706 |
109 |
0.019
|
|
|
|
sensory perception of umami taste
|
GO:0050917 |
4 |
0.019
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.019
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.019
|
|
|
|
locomotory behavior
|
GO:0007626 |
195 |
0.019
|
|
|
|
golgi to endosome transport
|
GO:0006895 |
3 |
0.019
|
|
|
|
negative regulation of protein catabolic process
|
GO:0042177 |
36 |
0.019
|
|
|
|
receptor mediated endocytosis
|
GO:0006898 |
51 |
0.019
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
88 |
0.019
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.019
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.019
|
|
|
|
regulation of peptidyl lysine acetylation
|
GO:2000756 |
22 |
0.019
|
|
|
|
histone h3 k9 acetylation
|
GO:0043970 |
5 |
0.019
|
|
|
|
regulation of b cell activation
|
GO:0050864 |
81 |
0.019
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
61 |
0.019
|
|
|
|
positive regulation of ossification
|
GO:0045778 |
47 |
0.019
|
|
|
|
regulation of transcription from rna polymerase iii promoter
|
GO:0006359 |
2 |
0.019
|
|
|
|
placenta development
|
GO:0001890 |
140 |
0.019
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.019
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.019
|
|
|
|
myd88 independent toll like receptor signaling pathway
|
GO:0002756 |
3 |
0.019
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.019
|
|
|
|
meiotic nuclear division
|
GO:0007126 |
115 |
0.019
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.018
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.018
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.018
|
|
|
|
regulation of fat cell differentiation
|
GO:0045598 |
81 |
0.018
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.018
|
|
|
|
negative regulation of immune effector process
|
GO:0002698 |
55 |
0.018
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.018
|
|
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.018
|
|
|
|
myosin filament assembly
|
GO:0031034 |
2 |
0.018
|
|
|
|
regulation of protein binding
|
GO:0043393 |
60 |
0.018
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
3 |
0.018
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.018
|
|
|
|
neuroblast differentiation
|
GO:0014016 |
2 |
0.018
|
|
|
|
lamellipodium morphogenesis
|
GO:0072673 |
5 |
0.018
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.018
|
|
|
|
blastocyst development
|
GO:0001824 |
80 |
0.018
|
|
|
|
mammary gland epithelium development
|
GO:0061180 |
65 |
0.018
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
234 |
0.018
|
|
|
|
focal adhesion assembly
|
GO:0048041 |
19 |
0.018
|
|
|
|
negative regulation of t cell activation
|
GO:0050868 |
65 |
0.018
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.018
|
|
|
|
stem cell proliferation
|
GO:0072089 |
117 |
0.018
|
|
|
|
neural precursor cell proliferation
|
GO:0061351 |
121 |
0.018
|
|
|
|
regulation of stem cell proliferation
|
GO:0072091 |
78 |
0.018
|
|
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.018
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
130 |
0.018
|
|
|
|
interleukin 12 production
|
GO:0032615 |
32 |
0.018
|
|
|
|
cd4 positive alpha beta t cell activation
|
GO:0035710 |
45 |
0.018
|
|
|
|
negative regulation of myeloid cell differentiation
|
GO:0045638 |
38 |
0.018
|
|
|
|
positive regulation of interleukin 2 production
|
GO:0032743 |
19 |
0.018
|
|
|
|
platelet derived growth factor receptor alpha signaling pathway
|
GO:0035790 |
3 |
0.018
|
|
|
|
negative regulation of lymphocyte differentiation
|
GO:0045620 |
32 |
0.017
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.017
|
|
|
|
negative regulation of cytoskeleton organization
|
GO:0051494 |
36 |
0.017
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.017
|
|
