Mus musculus

0 known processes

Map3k6

mitogen-activated protein kinase kinase kinase 6

(Aliases: MGC159280,MEKK6,MAPKKK6,Ask2)

Map3k6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cell activation GO:0050865 289 0.143
ras protein signal transduction GO:0007265 77 0.125
positive regulation of apoptotic process GO:0043065 217 0.124
Mouse
cellular amino acid metabolic process GO:0006520 103 0.115
fat cell differentiation GO:0045444 160 0.113
epithelial tube morphogenesis GO:0060562 303 0.108
t cell activation GO:0042110 289 0.100
regulation of cellular amino acid metabolic process GO:0006521 5 0.096
response to oxidative stress GO:0006979 123 0.095
Mouse
regulation of hydrolase activity GO:0051336 246 0.095
negative regulation of immune system process GO:0002683 209 0.091
cytokine production GO:0001816 319 0.087
negative regulation of cell motility GO:2000146 61 0.086
regulation of organelle organization GO:0033043 289 0.085
amine metabolic process GO:0009308 45 0.080
negative regulation of molecular function GO:0044092 258 0.076
regulation of defense response GO:0031347 233 0.074
apoptotic signaling pathway GO:0097190 306 0.074
Mouse
regulation of cell motility GO:2000145 236 0.072
negative regulation of endopeptidase activity GO:0010951 44 0.071
negative regulation of cell migration GO:0030336 59 0.071
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.070
organic anion transport GO:0015711 137 0.069
response to oxygen levels GO:0070482 62 0.069
negative regulation of intracellular signal transduction GO:1902532 167 0.069
striated muscle tissue development GO:0014706 293 0.069
lymphocyte differentiation GO:0030098 242 0.068
developmental growth involved in morphogenesis GO:0060560 138 0.068
transmembrane transport GO:0055085 412 0.067
nucleotide metabolic process GO:0009117 332 0.065
response to transforming growth factor beta GO:0071559 88 0.065
cellular response to growth factor stimulus GO:0071363 197 0.065
negative regulation of endothelial cell migration GO:0010596 4 0.062
male gamete generation GO:0048232 285 0.061
positive regulation of mapk cascade GO:0043410 170 0.060
Human Mouse Fly
positive regulation of behavior GO:0048520 40 0.060
cation transport GO:0006812 399 0.060
regulation of peptidase activity GO:0052547 96 0.059
response to hypoxia GO:0001666 58 0.058
heterocycle catabolic process GO:0046700 280 0.058
negative regulation of protein metabolic process GO:0051248 282 0.057
epidermis development GO:0008544 187 0.056
cellular response to inorganic substance GO:0071241 37 0.055
blood vessel morphogenesis GO:0048514 285 0.055
nucleoside catabolic process GO:0009164 206 0.055
l amino acid transport GO:0015807 32 0.054
purine nucleoside catabolic process GO:0006152 205 0.053
positive regulation of monocyte chemotaxis GO:0090026 2 0.053
nucleoside phosphate metabolic process GO:0006753 338 0.052
multi multicellular organism process GO:0044706 109 0.052
purine nucleotide metabolic process GO:0006163 302 0.049
anion transport GO:0006820 177 0.048
positive regulation of cell development GO:0010720 237 0.048
ribose phosphate metabolic process GO:0019693 291 0.048
regulation of nucleotide metabolic process GO:0006140 169 0.047
sensory perception GO:0007600 245 0.047
aromatic compound catabolic process GO:0019439 286 0.047
response to organonitrogen compound GO:0010243 246 0.047
organic cyclic compound catabolic process GO:1901361 295 0.047
cellular homeostasis GO:0019725 240 0.047
cell adhesion GO:0007155 329 0.046
fatty acid metabolic process GO:0006631 121 0.046
response to inorganic substance GO:0010035 96 0.046
ameboidal type cell migration GO:0001667 128 0.045
regulation of lymphocyte activation GO:0051249 240 0.045
negative regulation of protein maturation GO:1903318 79 0.045
leukocyte differentiation GO:0002521 342 0.045
organonitrogen compound catabolic process GO:1901565 264 0.045
regulation of cell migration GO:0030334 219 0.045
regulation of interleukin 8 production GO:0032677 3 0.045
cellular amine metabolic process GO:0044106 44 0.045
protein modification by small protein conjugation or removal GO:0070647 207 0.044
response to growth factor GO:0070848 198 0.044
regulation of epidermal cell differentiation GO:0045604 21 0.044
membrane organization GO:0061024 245 0.044
immune response activating signal transduction GO:0002757 116 0.044
purine containing compound metabolic process GO:0072521 311 0.043
placenta development GO:0001890 140 0.043
t cell differentiation GO:0030217 174 0.043
regionalization GO:0003002 337 0.043
nephron epithelium development GO:0072009 92 0.043
epithelial cell proliferation GO:0050673 174 0.042
axonogenesis GO:0007409 274 0.041
cell type specific apoptotic process GO:0097285 268 0.041
negative regulation of hydrolase activity GO:0051346 71 0.041
extracellular matrix organization GO:0030198 147 0.041
small molecule biosynthetic process GO:0044283 132 0.041
positive regulation of programmed cell death GO:0043068 218 0.041
Mouse
protein maturation GO:0051604 176 0.040
negative regulation of cellular amine metabolic process GO:0033239 1 0.039
actin filament organization GO:0007015 113 0.039
cellular nitrogen compound catabolic process GO:0044270 280 0.039
regulation of apoptotic signaling pathway GO:2001233 197 0.039
regulation of cellular amine metabolic process GO:0033238 20 0.039
purine nucleoside triphosphate metabolic process GO:0009144 226 0.039
small gtpase mediated signal transduction GO:0007264 97 0.039
drug metabolic process GO:0017144 4 0.039
cell substrate adhesion GO:0031589 130 0.039
negative regulation of cellular protein metabolic process GO:0032269 247 0.038
interleukin 8 production GO:0032637 4 0.038
carboxylic acid biosynthetic process GO:0046394 86 0.038
regulation of transmembrane transport GO:0034762 128 0.038
myeloid cell differentiation GO:0030099 233 0.038
positive regulation of lymphocyte activation GO:0051251 140 0.038
regulation of hormone levels GO:0010817 211 0.038
immune effector process GO:0002252 321 0.038
regulation of chemotaxis GO:0050920 53 0.038
regulation of ion transmembrane transport GO:0034765 119 0.038
regulation of cellular ketone metabolic process GO:0010565 66 0.038
ribonucleoside triphosphate metabolic process GO:0009199 220 0.038
camera type eye development GO:0043010 266 0.038
nucleobase containing small molecule metabolic process GO:0055086 352 0.037
cell activation involved in immune response GO:0002263 126 0.037
regulation of cytokine production GO:0001817 266 0.037
inflammatory response GO:0006954 244 0.037
arachidonic acid metabolite production involved in inflammatory response GO:0002538 2 0.037
negative regulation of proteolysis GO:0045861 74 0.037
muscle cell differentiation GO:0042692 261 0.037
telencephalon development GO:0021537 186 0.037
purine containing compound catabolic process GO:0072523 213 0.037
regulation of protein serine threonine kinase activity GO:0071900 157 0.036
Human Mouse
regulation of protein maturation GO:1903317 96 0.036
organic hydroxy compound metabolic process GO:1901615 203 0.036
ribonucleotide metabolic process GO:0009259 291 0.036
macromolecule catabolic process GO:0009057 281 0.035
regulation of protein processing GO:0070613 96 0.035
regulation of leukocyte differentiation GO:1902105 159 0.035
muscle system process GO:0003012 141 0.035
response to decreased oxygen levels GO:0036293 59 0.035
leukocyte migration GO:0050900 124 0.035
cellular protein complex assembly GO:0043623 116 0.034
morphogenesis of embryonic epithelium GO:0016331 159 0.034
regulation of actin filament based process GO:0032970 99 0.034
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.034
gland development GO:0048732 330 0.034
nucleoside phosphate catabolic process GO:1901292 222 0.034
myoblast differentiation involved in skeletal muscle regeneration GO:0014835 3 0.034
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.034
regulation of fat cell differentiation GO:0045598 81 0.034
limb development GO:0060173 166 0.033
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.033
rho protein signal transduction GO:0007266 32 0.033
developmental maturation GO:0021700 193 0.033
Fly
nitrogen compound transport GO:0071705 271 0.033
regulation of cell cycle GO:0051726 281 0.033
cellular response to cytokine stimulus GO:0071345 189 0.033
spermatid differentiation GO:0048515 115 0.033
cellular response to oxidative stress GO:0034599 76 0.033
Mouse
mitochondrion organization GO:0007005 134 0.033
positive regulation of keratinocyte proliferation GO:0010838 4 0.032
germ cell development GO:0007281 185 0.032
purine ribonucleotide catabolic process GO:0009154 208 0.032
regulation of cellular component biogenesis GO:0044087 181 0.032
muscle contraction GO:0006936 101 0.032
regulation of circadian sleep wake cycle GO:0042749 3 0.032
synaptic transmission GO:0007268 329 0.032
leukotriene production involved in inflammatory response GO:0002540 2 0.031
renal system development GO:0072001 225 0.031
nucleotide catabolic process GO:0009166 217 0.031
regulation of system process GO:0044057 200 0.031
positive regulation of cell death GO:0010942 224 0.031
Mouse
germ line stem cell division GO:0042078 2 0.031
response to acid chemical GO:0001101 111 0.031
bmp signaling pathway GO:0030509 93 0.031
response to lipopolysaccharide GO:0032496 128 0.030
chromatin organization GO:0006325 206 0.030
locomotory behavior GO:0007626 195 0.030
alcohol metabolic process GO:0006066 116 0.030
positive regulation of cell activation GO:0050867 158 0.030
purine ribonucleoside metabolic process GO:0046128 241 0.030
muscle tissue development GO:0060537 308 0.030
purine ribonucleoside catabolic process GO:0046130 205 0.030
regulation of cell cycle process GO:0010564 160 0.029
leukocyte proliferation GO:0070661 172 0.029
divalent metal ion transport GO:0070838 172 0.029
cellular lipid metabolic process GO:0044255 323 0.029
peptidyl amino acid modification GO:0018193 336 0.029
septum primum development GO:0003284 4 0.029
cell chemotaxis GO:0060326 81 0.029
negative regulation of peptidase activity GO:0010466 46 0.029
purine nucleoside metabolic process GO:0042278 241 0.029
regulation of myeloid cell differentiation GO:0045637 96 0.029
regulation of hippo signaling GO:0035330 1 0.029
respiratory tube development GO:0030323 167 0.029
glycoprotein biosynthetic process GO:0009101 89 0.029
g protein coupled receptor signaling pathway GO:0007186 243 0.029
morphogenesis of a polarized epithelium GO:0001738 37 0.029
reactive oxygen species metabolic process GO:0072593 84 0.029
regulation of response to wounding GO:1903034 189 0.029
cerebellar cortex development GO:0021695 48 0.029
immune response regulating signaling pathway GO:0002764 125 0.028
leukocyte chemotaxis GO:0030595 69 0.028
ribonucleoside triphosphate catabolic process GO:0009203 199 0.028
regulation of monocyte chemotaxis GO:0090025 3 0.028
positive regulation of cell motility GO:2000147 116 0.028
response to metal ion GO:0010038 47 0.028
organelle fission GO:0048285 170 0.028
oxidation reduction process GO:0055114 342 0.028
transdifferentiation GO:0060290 1 0.028
skeletal system development GO:0001501 356 0.028
spermatogenesis GO:0007283 284 0.027
cellular response to external stimulus GO:0071496 88 0.027
carbohydrate metabolic process GO:0005975 230 0.027
carbohydrate derivative biosynthetic process GO:1901137 183 0.027
response to radiation GO:0009314 165 0.027
negative regulation of blood vessel endothelial cell migration GO:0043537 3 0.027
antibacterial peptide biosynthetic process GO:0002780 2 0.027
purine nucleoside triphosphate catabolic process GO:0009146 203 0.027
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.027
cellular ketone metabolic process GO:0042180 84 0.027
nucleoside triphosphate metabolic process GO:0009141 230 0.027
purine ribonucleotide metabolic process GO:0009150 290 0.027
response to molecule of bacterial origin GO:0002237 143 0.027
regulation of nucleoside metabolic process GO:0009118 130 0.027
intrinsic apoptotic signaling pathway GO:0097193 132 0.027
Mouse
ribonucleoside metabolic process GO:0009119 245 0.027
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.027
positive regulation of cell migration GO:0030335 109 0.027
response to organic cyclic compound GO:0014070 198 0.027
glycosyl compound catabolic process GO:1901658 206 0.027
muscle cell development GO:0055001 133 0.027
protein ubiquitination GO:0016567 171 0.027
regulation of epidermis development GO:0045682 33 0.027
brown fat cell differentiation GO:0050873 36 0.026
posttranscriptional regulation of gene expression GO:0010608 155 0.026
response to oxygen radical GO:0000305 16 0.026
regulation of t cell activation GO:0050863 170 0.026
ossification GO:0001503 216 0.026
positive regulation of mitotic cell cycle GO:0045931 41 0.026
erythrocyte differentiation GO:0030218 88 0.026
b cell activation GO:0042113 161 0.026
organ growth GO:0035265 117 0.026
regulation of ion transport GO:0043269 215 0.026
response to hydrogen peroxide GO:0042542 32 0.026
cell cycle g1 s phase transition GO:0044843 57 0.026
organonitrogen compound biosynthetic process GO:1901566 192 0.026
protein modification by small protein conjugation GO:0032446 187 0.026
regulation of vasculature development GO:1901342 88 0.026
positive regulation of cellular amine metabolic process GO:0033240 5 0.026
stem cell differentiation GO:0048863 268 0.025
astrocyte fate commitment GO:0060018 4 0.025
nuclear division GO:0000280 158 0.025
response to extracellular stimulus GO:0009991 127 0.025
skeletal muscle fiber development GO:0048741 58 0.025
regulation of cell substrate adhesion GO:0010810 73 0.025
glycosyl compound metabolic process GO:1901657 246 0.025
actin cytoskeleton organization GO:0030036 220 0.025
divalent inorganic cation transport GO:0072511 178 0.025
purine nucleotide catabolic process GO:0006195 211 0.025
positive regulation of organelle organization GO:0010638 128 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.025
lymphocyte proliferation GO:0046651 164 0.025
regulation of transferase activity GO:0051338 263 0.025
Human Mouse
histone modification GO:0016570 159 0.025
neural tube development GO:0021915 160 0.025
oviduct development GO:0060066 3 0.024
adult locomotory behavior GO:0008344 91 0.024
leukocyte apoptotic process GO:0071887 71 0.024
single organismal cell cell adhesion GO:0016337 131 0.024
negative regulation of peroxisome proliferator activated receptor signaling pathway GO:0035359 3 0.024
regulation of angiogenesis GO:0045765 81 0.024
myeloid leukocyte migration GO:0097529 57 0.024
urogenital system development GO:0001655 261 0.024
protein processing GO:0016485 163 0.024
regulation of cell adhesion GO:0030155 154 0.024
ribonucleoside catabolic process GO:0042454 206 0.024
homeostasis of number of cells GO:0048872 210 0.024
negative regulation of ossification GO:0030279 49 0.023
regulation of inflammatory response GO:0050727 147 0.023
regulation of vesicle mediated transport GO:0060627 139 0.023
tissue migration GO:0090130 68 0.023
cellular response to molecule of bacterial origin GO:0071219 83 0.023
regulation of intracellular transport GO:0032386 159 0.023
learning or memory GO:0007611 148 0.023
hindbrain development GO:0030902 128 0.023
negative regulation of cell proliferation GO:0008285 296 0.023
protein catabolic process GO:0030163 221 0.023
fibrinolysis GO:0042730 3 0.023
mesonephros development GO:0001823 97 0.023
response to hyperoxia GO:0055093 2 0.023
organophosphate catabolic process GO:0046434 232 0.023
myeloid cell homeostasis GO:0002262 114 0.022
exocytosis GO:0006887 121 0.022
negative regulation of phospholipase activity GO:0010519 4 0.022
negative regulation of protein modification process GO:0031400 163 0.022
spermatid development GO:0007286 108 0.022
male germ line stem cell asymmetric division GO:0048133 2 0.022
cerebellum development GO:0021549 77 0.022
morphogenesis of a branching epithelium GO:0061138 193 0.022
positive regulation of interleukin 8 production GO:0032757 2 0.022
asymmetric stem cell division GO:0098722 3 0.022
compound eye development GO:0048749 1 0.022
cognition GO:0050890 149 0.022
mitotic cell cycle process GO:1903047 159 0.022
multicellular organismal macromolecule metabolic process GO:0044259 19 0.022
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.022
terpenoid metabolic process GO:0006721 25 0.022
positive regulation of leukocyte differentiation GO:1902107 86 0.022
epithelial cell migration GO:0010631 63 0.022
negative regulation of cell adhesion GO:0007162 45 0.022
cellular response to hormone stimulus GO:0032870 150 0.022
second messenger mediated signaling GO:0019932 73 0.021
skeletal muscle organ development GO:0060538 163 0.021
covalent chromatin modification GO:0016569 163 0.021
regulation of cellular response to growth factor stimulus GO:0090287 82 0.021
positive regulation of defense response GO:0031349 124 0.021
negative regulation of lymphocyte activation GO:0051250 91 0.021
organic acid biosynthetic process GO:0016053 86 0.021
regulation of actin cytoskeleton organization GO:0032956 84 0.021
regulation of reproductive process GO:2000241 66 0.021
regulation of protein localization GO:0032880 231 0.021
cell growth GO:0016049 130 0.021
multi organism behavior GO:0051705 62 0.021
wound healing GO:0042060 157 0.021
stress activated mapk cascade GO:0051403 80 0.021
Fly
cation transmembrane transport GO:0098655 266 0.020
sensory organ morphogenesis GO:0090596 242 0.020
endomembrane system organization GO:0010256 147 0.020
response to reactive oxygen species GO:0000302 56 0.020
av node cell to bundle of his cell communication GO:0086067 2 0.020
mesonephric duct morphogenesis GO:0072180 4 0.020
carbohydrate derivative catabolic process GO:1901136 231 0.020
organophosphate biosynthetic process GO:0090407 122 0.020
negative regulation of cell cycle GO:0045786 123 0.020
striated muscle cell development GO:0055002 125 0.020
positive regulation of cell adhesion GO:0045785 80 0.020
regulation of cell growth GO:0001558 91 0.020
sequestering of calcium ion GO:0051208 18 0.020
negative regulation of myeloid cell differentiation GO:0045638 38 0.020
positive regulation of protein modification process GO:0031401 299 0.020
Human Mouse
regulation of exit from mitosis GO:0007096 1 0.020
monocarboxylic acid biosynthetic process GO:0072330 61 0.020
platelet activation GO:0030168 40 0.020
negative regulation of ion transport GO:0043271 28 0.020
regulation of muscle system process GO:0090257 80 0.020
cellular calcium ion homeostasis GO:0006874 119 0.020
b cell differentiation GO:0030183 78 0.020
response to epidermal growth factor GO:0070849 4 0.020
meiotic nuclear division GO:0007126 115 0.019
sphingolipid metabolic process GO:0006665 45 0.019
mesenchyme development GO:0060485 152 0.019
cell division GO:0051301 120 0.019
lens development in camera type eye GO:0002088 62 0.019
single organism cell adhesion GO:0098602 156 0.019
regulation of purine nucleotide metabolic process GO:1900542 169 0.019
positive regulation of cell cycle process GO:0090068 61 0.019
metencephalon development GO:0022037 89 0.019
nephron tubule development GO:0072080 84 0.019
midgut development GO:0007494 4 0.019
hematopoietic progenitor cell differentiation GO:0002244 143 0.019
mitral valve morphogenesis GO:0003183 4 0.019
cell recognition GO:0008037 83 0.019
cellular ion homeostasis GO:0006873 165 0.019
leukocyte activation involved in immune response GO:0002366 126 0.019
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.019
regulation of nucleotide catabolic process GO:0030811 122 0.019
mitral valve development GO:0003174 4 0.019
neural tube closure GO:0001843 90 0.019
negative regulation of apoptotic signaling pathway GO:2001234 104 0.019
striated muscle contraction GO:0006941 45 0.018
regulation of protein stability GO:0031647 52 0.018
kidney epithelium development GO:0072073 121 0.018
meiotic cell cycle GO:0051321 122 0.018
regulation of cell shape GO:0008360 39 0.018
Fly
determination of heart left right asymmetry GO:0061371 48 0.018
regulation of cytoskeleton organization GO:0051493 122 0.018
endothelial cell apoptotic process GO:0072577 9 0.018
endocytosis GO:0006897 168 0.018
regulation of binding GO:0051098 111 0.018
positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060501 3 0.018
t helper 1 cell cytokine production GO:0035744 1 0.018
skin development GO:0043588 220 0.018
ribonucleoside monophosphate metabolic process GO:0009161 80 0.018
adult behavior GO:0030534 135 0.018
response to organophosphorus GO:0046683 22 0.018
appendage morphogenesis GO:0035107 149 0.018
organic hydroxy compound biosynthetic process GO:1901617 77 0.018
rna interference GO:0016246 2 0.018
regulation of blood pressure GO:0008217 93 0.018
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.018
neural tube formation GO:0001841 108 0.018
amide transport GO:0042886 138 0.018
development of primary sexual characteristics GO:0045137 143 0.018
negative regulation of cell adhesion mediated by integrin GO:0033629 2 0.017
g1 s transition of mitotic cell cycle GO:0000082 57 0.017
positive regulation of insulin receptor signaling pathway GO:0046628 4 0.017
positive regulation of leukocyte proliferation GO:0070665 73 0.017
negative regulation of growth GO:0045926 99 0.017
positive regulation of t cell activation GO:0050870 101 0.017
angiogenesis GO:0001525 201 0.017
reproductive behavior GO:0019098 32 0.017
alpha beta t cell differentiation GO:0046632 69 0.017
methylation GO:0032259 134 0.017
response to drug GO:0042493 75 0.017
regulation of neuron death GO:1901214 134 0.017
mitotic cell cycle GO:0000278 195 0.017
dna metabolic process GO:0006259 303 0.017
regulation of metal ion transport GO:0010959 106 0.017
cellular response to dna damage stimulus GO:0006974 207 0.017
response to insulin GO:0032868 100 0.017
formation of organ boundary GO:0010160 1 0.017
activation of immune response GO:0002253 138 0.017
positive regulation of angiogenesis GO:0045766 46 0.017
regulation of fibroblast proliferation GO:0048145 34 0.017
embryonic organ morphogenesis GO:0048562 276 0.017
jnk cascade GO:0007254 72 0.017
Fly
positive regulation of hydrolase activity GO:0051345 148 0.017
positive regulation of phagocytosis engulfment GO:0060100 3 0.017
protein localization to membrane GO:0072657 108 0.017
nucleoside triphosphate catabolic process GO:0009143 205 0.017
positive regulation of protein phosphorylation GO:0001934 242 0.017
Human Mouse
regulation of cellular component size GO:0032535 121 0.017
positive regulation of response to wounding GO:1903036 66 0.017
mapk cascade GO:0000165 281 0.017
Human Mouse Fly
mrna metabolic process GO:0016071 84 0.017
cardiac muscle fiber development GO:0048739 4 0.016
autonomic nervous system development GO:0048483 43 0.016
maintenance of location GO:0051235 89 0.016
regulation of auditory receptor cell differentiation GO:0045607 4 0.016
unsaturated fatty acid biosynthetic process GO:0006636 15 0.016
embryonic heart tube development GO:0035050 65 0.016
regulation of protein transport GO:0051223 163 0.016
fibroblast migration GO:0010761 21 0.016
regulation of mitotic cell cycle GO:0007346 126 0.016
regulation of myeloid leukocyte differentiation GO:0002761 58 0.016
germline stem cell asymmetric division GO:0098728 2 0.016
chemotaxis GO:0006935 247 0.016
ureteric bud development GO:0001657 94 0.016
embryonic epithelial tube formation GO:0001838 130 0.016
limb morphogenesis GO:0035108 149 0.016
negative regulation of cell activation GO:0050866 111 0.016
embryonic placenta development GO:0001892 98 0.016
negative regulation of bmp signaling pathway GO:0030514 35 0.016
developmental cell growth GO:0048588 84 0.016
striated muscle myosin thick filament assembly GO:0071688 1 0.016
regulation of innate immune response GO:0045088 91 0.016
ribonucleotide catabolic process GO:0009261 208 0.016
positive regulation of epidermis development GO:0045684 13 0.016
atp metabolic process GO:0046034 75 0.016
macromolecule methylation GO:0043414 120 0.016
cellular chemical homeostasis GO:0055082 215 0.016
trunk segmentation GO:0035290 4 0.016
vesicle organization GO:0016050 60 0.016
cartilage development GO:0051216 140 0.016
regulation of homeostatic process GO:0032844 182 0.016
nucleoside monophosphate metabolic process GO:0009123 85 0.016
embryonic heart tube morphogenesis GO:0003143 51 0.016
positive regulation of endocytosis GO:0045807 42 0.016
cellular macromolecule catabolic process GO:0044265 206 0.016
lipid biosynthetic process GO:0008610 179 0.016
intracellular protein transport GO:0006886 204 0.016
regulation of mast cell differentiation GO:0060375 3 0.016
planar cell polarity pathway involved in heart morphogenesis GO:0061346 3 0.016
neurotransmitter transport GO:0006836 76 0.016
protein localization to organelle GO:0033365 185 0.016
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.016
regulation of ras protein signal transduction GO:0046578 114 0.016
pigmentation GO:0043473 71 0.016
Fly
positive regulation of cellular component biogenesis GO:0044089 94 0.016
defense response to bacterium GO:0042742 119 0.016
regulation of endothelial cell apoptotic process GO:2000351 9 0.016
blood coagulation GO:0007596 76 0.015
positive regulation of secretion by cell GO:1903532 114 0.015
retina development in camera type eye GO:0060041 119 0.015
axis elongation involved in somitogenesis GO:0090245 4 0.015
negative regulation of response to wounding GO:1903035 77 0.015
positive regulation of cell cycle GO:0045787 92 0.015
response to starvation GO:0042594 65 0.015
cellular response to extracellular stimulus GO:0031668 81 0.015
branching morphogenesis of an epithelial tube GO:0048754 159 0.015
alpha beta t cell activation GO:0046631 91 0.015
divalent inorganic cation homeostasis GO:0072507 138 0.015
planar cell polarity pathway involved in outflow tract morphogenesis GO:0061347 2 0.015
regulation of multi organism process GO:0043900 111 0.015
regulation of lymphocyte differentiation GO:0045619 107 0.015
regulation of fibrinolysis GO:0051917 1 0.015
cellular response to organonitrogen compound GO:0071417 145 0.015
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.015
Human Mouse
rna processing GO:0006396 105 0.015
regulation of protein complex assembly GO:0043254 83 0.015
cardiac muscle tissue development GO:0048738 130 0.015
negative regulation of oxidative phosphorylation uncoupler activity GO:2000276 2 0.015
wnt signaling pathway GO:0016055 188 0.015
cellular response to metal ion GO:0071248 31 0.015
lateral inhibition GO:0046331 1 0.015

Map3k6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.089
nervous system disease DOID:863 0 0.089
neuromuscular disease DOID:440 0 0.080
charcot marie tooth disease DOID:10595 0 0.080
neuropathy DOID:870 0 0.080
disease of metabolism DOID:0014667 0 0.042
sensory system disease DOID:0050155 0 0.033
eye and adnexa disease DOID:1492 0 0.033
eye disease DOID:5614 0 0.033
cardiovascular system disease DOID:1287 0 0.030
retinal disease DOID:5679 0 0.017