Mus musculus

0 known processes

Pdzrn4

PDZ domain containing RING finger 4

(Aliases: 1110017D07Rik,KIAA3027,LNX4,SAMCAP3L,mKIAA3027)

Pdzrn4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell adhesion GO:0007155 329 0.077
cellular amino acid metabolic process GO:0006520 103 0.070
action potential GO:0001508 78 0.059
blood circulation GO:0008015 195 0.058
muscle tissue development GO:0060537 308 0.055
cell type specific apoptotic process GO:0097285 268 0.055
transmembrane transport GO:0055085 412 0.054
ion transmembrane transport GO:0034220 361 0.051
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.048
axonogenesis GO:0007409 274 0.048
transmission of nerve impulse GO:0019226 76 0.046
regulation of neuron differentiation GO:0045664 281 0.045
developmental growth involved in morphogenesis GO:0060560 138 0.043
cell fate commitment GO:0045165 210 0.043
muscle cell differentiation GO:0042692 261 0.042
striated muscle tissue development GO:0014706 293 0.042
regulation of cellular amino acid metabolic process GO:0006521 5 0.042
forebrain development GO:0030900 302 0.041
multicellular organismal signaling GO:0035637 91 0.041
amine metabolic process GO:0009308 45 0.041
retina development in camera type eye GO:0060041 119 0.040
camera type eye development GO:0043010 266 0.040
mapk cascade GO:0000165 281 0.039
renal system development GO:0072001 225 0.038
tube formation GO:0035148 140 0.037
cellular ketone metabolic process GO:0042180 84 0.037
gland development GO:0048732 330 0.036
wnt signaling pathway GO:0016055 188 0.035
epithelial tube morphogenesis GO:0060562 303 0.035
kidney development GO:0001822 213 0.035
regulation of protein localization GO:0032880 231 0.034
urogenital system development GO:0001655 261 0.034
canonical wnt signaling pathway GO:0060070 130 0.033
learning or memory GO:0007611 148 0.033
protein catabolic process GO:0030163 221 0.033
macromolecule catabolic process GO:0009057 281 0.032
positive regulation of cell development GO:0010720 237 0.032
locomotory behavior GO:0007626 195 0.031
morphogenesis of embryonic epithelium GO:0016331 159 0.031
cellular amine metabolic process GO:0044106 44 0.031
central nervous system neuron differentiation GO:0021953 162 0.031
skeletal system development GO:0001501 356 0.030
heart process GO:0003015 94 0.030
peptidyl amino acid modification GO:0018193 336 0.030
neuron apoptotic process GO:0051402 142 0.030
heart morphogenesis GO:0003007 178 0.029
negative regulation of cell development GO:0010721 169 0.029
inorganic ion transmembrane transport GO:0098660 234 0.028
positive regulation of mapk cascade GO:0043410 170 0.028
regulation of cellular amine metabolic process GO:0033238 20 0.028
positive regulation of protein modification process GO:0031401 299 0.028
neuronal action potential GO:0019228 54 0.028
chemotaxis GO:0006935 247 0.028
cellular response to organonitrogen compound GO:0071417 145 0.028
sensory perception GO:0007600 245 0.028
neuron death GO:0070997 154 0.027
regulation of anatomical structure size GO:0090066 178 0.027
circulatory system process GO:0003013 197 0.027
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.027
positive regulation of protein phosphorylation GO:0001934 242 0.027
membrane organization GO:0061024 245 0.027
sensory perception of mechanical stimulus GO:0050954 107 0.026
oxidation reduction process GO:0055114 342 0.026
response to organonitrogen compound GO:0010243 246 0.026
positive regulation of nervous system development GO:0051962 221 0.026
mesodermal cell migration GO:0008078 4 0.026
regulation of cell adhesion GO:0030155 154 0.025
regulation of cellular ketone metabolic process GO:0010565 66 0.025
cell growth GO:0016049 130 0.025
positive regulation of cellular amine metabolic process GO:0033240 5 0.025
skin development GO:0043588 220 0.025
regulation of membrane potential GO:0042391 192 0.024
apoptotic signaling pathway GO:0097190 306 0.024
retina morphogenesis in camera type eye GO:0060042 45 0.024
regulation of establishment of protein localization GO:0070201 181 0.023
regulation of cell projection organization GO:0031344 206 0.023
negative regulation of cellular protein metabolic process GO:0032269 247 0.023
embryonic organ morphogenesis GO:0048562 276 0.023
cognition GO:0050890 149 0.023
gliogenesis GO:0042063 141 0.023
regulation of mapk cascade GO:0043408 248 0.023
cation transmembrane transport GO:0098655 266 0.023
dna metabolic process GO:0006259 303 0.023
regulation of ion transmembrane transport GO:0034765 119 0.023
regulation of hydrolase activity GO:0051336 246 0.023
organelle fission GO:0048285 170 0.022
regulation of system process GO:0044057 200 0.022
nucleoside phosphate metabolic process GO:0006753 338 0.022
organic hydroxy compound metabolic process GO:1901615 203 0.022
cardiac muscle contraction GO:0060048 32 0.022
nuclear division GO:0000280 158 0.021
epithelial tube formation GO:0072175 130 0.021
protein localization to membrane GO:0072657 108 0.021
regulation of neuron apoptotic process GO:0043523 122 0.021
posttranscriptional regulation of gene expression GO:0010608 155 0.021
epidermis development GO:0008544 187 0.021
regulation of protein serine threonine kinase activity GO:0071900 157 0.021
ear development GO:0043583 200 0.021
negative regulation of cell projection organization GO:0031345 56 0.021
single organism cell adhesion GO:0098602 156 0.021
g protein coupled receptor signaling pathway GO:0007186 243 0.021
response to organic cyclic compound GO:0014070 198 0.021
positive regulation of transferase activity GO:0051347 167 0.021
protein modification by small protein conjugation or removal GO:0070647 207 0.021
cellular component assembly involved in morphogenesis GO:0010927 139 0.021
t cell activation GO:0042110 289 0.021
regionalization GO:0003002 337 0.020
cytoplasmic transport GO:0016482 234 0.020
t cell differentiation GO:0030217 174 0.020
regulation of neuron projection development GO:0010975 169 0.020
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.020
regulation of organ morphogenesis GO:2000027 144 0.020
protein modification by small protein conjugation GO:0032446 187 0.020
skeletal system morphogenesis GO:0048705 203 0.020
cytokine production GO:0001816 319 0.020
regulation of proteolysis GO:0030162 164 0.020
lymphocyte differentiation GO:0030098 242 0.020
negative regulation of molecular function GO:0044092 258 0.019
regulation of wnt signaling pathway GO:0030111 123 0.019
negative regulation of protein metabolic process GO:0051248 282 0.019
actin cytoskeleton organization GO:0030036 220 0.019
positive regulation of cell adhesion GO:0045785 80 0.019
lung development GO:0030324 164 0.019
cardiac muscle tissue development GO:0048738 130 0.019
regulation of kinase activity GO:0043549 249 0.019
negative regulation of neuron death GO:1901215 98 0.019
cation transport GO:0006812 399 0.019
cell maturation GO:0048469 127 0.019
leukocyte differentiation GO:0002521 342 0.019
regulation of cell motility GO:2000145 236 0.019
regulation of transferase activity GO:0051338 263 0.019
nucleobase containing small molecule metabolic process GO:0055086 352 0.019
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.019
lateral inhibition GO:0046331 1 0.019
regulation of map kinase activity GO:0043405 120 0.019
nucleotide metabolic process GO:0009117 332 0.019
negative regulation of nervous system development GO:0051961 156 0.019
regulation of neuron death GO:1901214 134 0.019
regulation of organelle organization GO:0033043 289 0.018
developmental cell growth GO:0048588 84 0.018
protein ubiquitination GO:0016567 171 0.018
positive regulation of neuron differentiation GO:0045666 141 0.018
intracellular protein transport GO:0006886 204 0.018
synaptic transmission GO:0007268 329 0.018
gonad development GO:0008406 141 0.018
regulation of blood circulation GO:1903522 93 0.018
negative regulation of phosphorylation GO:0042326 166 0.018
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.018
actin mediated cell contraction GO:0070252 15 0.018
hindbrain development GO:0030902 128 0.018
negative regulation of neuron apoptotic process GO:0043524 92 0.018
embryonic epithelial tube formation GO:0001838 130 0.018
negative regulation of intracellular signal transduction GO:1902532 167 0.017
purine nucleotide metabolic process GO:0006163 302 0.017
regulation of ion transport GO:0043269 215 0.017
immune effector process GO:0002252 321 0.017
spermatogenesis GO:0007283 284 0.017
neural tube formation GO:0001841 108 0.017
positive regulation of protein kinase activity GO:0045860 144 0.017
regulation of cell migration GO:0030334 219 0.017
positive regulation of kinase activity GO:0033674 155 0.017
regulation of cell activation GO:0050865 289 0.017
morphogenesis of a branching epithelium GO:0061138 193 0.017
neuron projection guidance GO:0097485 141 0.017
cardiocyte differentiation GO:0035051 87 0.017
fertilization GO:0009566 127 0.017
epithelial cell development GO:0002064 159 0.017
regulation of heart contraction GO:0008016 77 0.017
negative regulation of cellular component organization GO:0051129 194 0.017
sensory organ morphogenesis GO:0090596 242 0.017
negative regulation of cell proliferation GO:0008285 296 0.016
negative regulation of wnt signaling pathway GO:0030178 73 0.016
learning GO:0007612 98 0.016
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.016
regulation of protein kinase activity GO:0045859 232 0.016
response to radiation GO:0009314 165 0.016
sensory perception of sound GO:0007605 97 0.016
organ growth GO:0035265 117 0.016
cellular macromolecule catabolic process GO:0044265 206 0.016
glial cell differentiation GO:0010001 131 0.016
single organismal cell cell adhesion GO:0016337 131 0.016
hematopoietic progenitor cell differentiation GO:0002244 143 0.016
cardiac chamber development GO:0003205 108 0.016
cellular homeostasis GO:0019725 240 0.016
muscle contraction GO:0006936 101 0.016
negative regulation of phosphorus metabolic process GO:0010563 184 0.016
respiratory tube development GO:0030323 167 0.016
eye photoreceptor cell differentiation GO:0001754 41 0.016
cardiac ventricle development GO:0003231 83 0.016
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.016
heterocycle catabolic process GO:0046700 280 0.015
ossification GO:0001503 216 0.015
adult behavior GO:0030534 135 0.015
axon guidance GO:0007411 141 0.015
stem cell differentiation GO:0048863 268 0.015
neuron migration GO:0001764 122 0.015
regulation of binding GO:0051098 111 0.015
muscle system process GO:0003012 141 0.015
organelle assembly GO:0070925 177 0.015
morphogenesis of a branching structure GO:0001763 203 0.015
male gamete generation GO:0048232 285 0.015
regulation of actin filament based process GO:0032970 99 0.015
angiogenesis GO:0001525 201 0.015
skeletal muscle organ development GO:0060538 163 0.015
regulation of protein transport GO:0051223 163 0.015
multi organism behavior GO:0051705 62 0.015
placenta development GO:0001890 140 0.015
ribonucleotide catabolic process GO:0009261 208 0.015
heart contraction GO:0060047 93 0.015
organelle localization GO:0051640 179 0.015
respiratory system development GO:0060541 190 0.015
cellular response to hormone stimulus GO:0032870 150 0.015
regulation of cell growth GO:0001558 91 0.015
positive regulation of programmed cell death GO:0043068 218 0.015
regulation of intracellular transport GO:0032386 159 0.015
response to peptide GO:1901652 136 0.015
compound eye development GO:0048749 1 0.015
meiotic nuclear division GO:0007126 115 0.015
cellular lipid metabolic process GO:0044255 323 0.014
telencephalon development GO:0021537 186 0.014
tube closure GO:0060606 91 0.014
striated muscle contraction GO:0006941 45 0.014
cell junction organization GO:0034330 77 0.014
protein localization to organelle GO:0033365 185 0.014
ribonucleotide metabolic process GO:0009259 291 0.014
myelination GO:0042552 74 0.014
homeostasis of number of cells GO:0048872 210 0.014
digestive system development GO:0055123 200 0.014
development of primary sexual characteristics GO:0045137 143 0.014
regulation of homeostatic process GO:0032844 182 0.014
inorganic cation transmembrane transport GO:0098662 207 0.014
regulation of muscle tissue development GO:1901861 97 0.014
cell division GO:0051301 120 0.014
cardiac muscle cell contraction GO:0086003 7 0.014
regulation of transmembrane transport GO:0034762 128 0.014
spinal cord development GO:0021510 81 0.014
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.014
branching morphogenesis of an epithelial tube GO:0048754 159 0.014
aromatic compound catabolic process GO:0019439 286 0.014
muscle cell development GO:0055001 133 0.014
glycoprotein biosynthetic process GO:0009101 89 0.014
synapse organization GO:0050808 125 0.014
cation homeostasis GO:0055080 212 0.013
cellular nitrogen compound catabolic process GO:0044270 280 0.013
cellular response to lipid GO:0071396 145 0.013
carbohydrate derivative biosynthetic process GO:1901137 183 0.013
extracellular matrix organization GO:0030198 147 0.013
regulation of cytoplasmic transport GO:1903649 112 0.013
ameboidal type cell migration GO:0001667 128 0.013
meiotic cell cycle GO:0051321 122 0.013
organonitrogen compound catabolic process GO:1901565 264 0.013
cellular response to peptide GO:1901653 92 0.013
purine ribonucleotide catabolic process GO:0009154 208 0.013
purine containing compound metabolic process GO:0072521 311 0.013
regulation of metal ion transport GO:0010959 106 0.013
myotube differentiation GO:0014902 105 0.013
developmental maturation GO:0021700 193 0.013
connective tissue development GO:0061448 179 0.013
negative regulation of apoptotic signaling pathway GO:2001234 104 0.013
cell recognition GO:0008037 83 0.013
regulation of cell cycle GO:0051726 281 0.013
defense response to other organism GO:0098542 197 0.013
neural tube development GO:0021915 160 0.013
reactive oxygen species metabolic process GO:0072593 84 0.013
dendrite development GO:0016358 115 0.013
negative regulation of protein modification process GO:0031400 163 0.013
fat cell differentiation GO:0045444 160 0.013
negative regulation of cellular amine metabolic process GO:0033239 1 0.013
adaptive immune response GO:0002250 155 0.013
regulation of cellular component biogenesis GO:0044087 181 0.013
neuromuscular process GO:0050905 99 0.013
ras protein signal transduction GO:0007265 77 0.013
divalent inorganic cation transport GO:0072511 178 0.012
protein maturation GO:0051604 176 0.012
negative regulation of phosphate metabolic process GO:0045936 184 0.012
small molecule biosynthetic process GO:0044283 132 0.012
microtubule based process GO:0007017 236 0.012
asymmetric stem cell division GO:0098722 3 0.012
innate immune response GO:0045087 157 0.012
engulfment of apoptotic cell GO:0043652 3 0.012
neuron projection extension GO:1990138 64 0.012
positive regulation of cell death GO:0010942 224 0.012
appendage development GO:0048736 166 0.012
embryonic placenta development GO:0001892 98 0.012
tissue migration GO:0090130 68 0.012
carbohydrate metabolic process GO:0005975 230 0.012
response to inorganic substance GO:0010035 96 0.012
metencephalon development GO:0022037 89 0.012
organic cyclic compound catabolic process GO:1901361 295 0.012
female sex differentiation GO:0046660 84 0.012
response to light stimulus GO:0009416 135 0.012
regulation of cytokine production GO:0001817 266 0.012
regulation of cellular catabolic process GO:0031329 242 0.012
axon ensheathment GO:0008366 76 0.012
positive regulation of map kinase activity GO:0043406 84 0.012
regulation of peptidase activity GO:0052547 96 0.012
pallium development GO:0021543 120 0.012
inflammatory response GO:0006954 244 0.012
photoreceptor cell differentiation GO:0046530 52 0.012
primary neural tube formation GO:0014020 95 0.012
bone development GO:0060348 120 0.012
dorsal ventral axon guidance GO:0033563 3 0.012
cellular protein complex assembly GO:0043623 116 0.012
cell substrate adhesion GO:0031589 130 0.012
response to acid chemical GO:0001101 111 0.012
regulation of response to wounding GO:1903034 189 0.012
actin filament based movement GO:0030048 23 0.012
regulation of cell substrate adhesion GO:0010810 73 0.012
cellular chemical homeostasis GO:0055082 215 0.012
regulation of apoptotic signaling pathway GO:2001233 197 0.012
cellular carbohydrate metabolic process GO:0044262 119 0.012
establishment of blood nerve barrier GO:0008065 3 0.012
positive regulation of apoptotic process GO:0043065 217 0.012
lymphocyte activation involved in immune response GO:0002285 93 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.012
myeloid cell differentiation GO:0030099 233 0.012
cerebral cortex development GO:0021987 86 0.012
sa node cell action potential GO:0086015 4 0.012
regulation of striated muscle cell differentiation GO:0051153 81 0.012
nucleocytoplasmic transport GO:0006913 139 0.012
regulation of intracellular protein transport GO:0033157 82 0.012
ensheathment of neurons GO:0007272 76 0.012
small gtpase mediated signal transduction GO:0007264 97 0.011
purine nucleoside metabolic process GO:0042278 241 0.011
purine ribonucleotide metabolic process GO:0009150 290 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.011
myeloid cell homeostasis GO:0002262 114 0.011
neural precursor cell proliferation GO:0061351 121 0.011
organophosphate catabolic process GO:0046434 232 0.011
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.011
cardiac chamber morphogenesis GO:0003206 93 0.011
regulation of axon extension GO:0030516 43 0.011
mechanoreceptor differentiation GO:0042490 67 0.011
negative regulation of protein phosphorylation GO:0001933 126 0.011
sensory system development GO:0048880 3 0.011
regulation of protein catabolic process GO:0042176 108 0.011
glycoprotein metabolic process GO:0009100 116 0.011
regulation of defense response GO:0031347 233 0.011
female gonad development GO:0008585 71 0.011
striated muscle cell development GO:0055002 125 0.011
cardiac septum development GO:0003279 59 0.011
stem cell proliferation GO:0072089 117 0.011
negative regulation of neuron differentiation GO:0045665 101 0.011
regulation of cellular component size GO:0032535 121 0.011
positive regulation of inositol phosphate biosynthetic process GO:0060732 2 0.011
positive regulation of cytokine production GO:0001819 174 0.011
nuclear transport GO:0051169 139 0.011
photoreceptor cell development GO:0042461 40 0.011
lipid transport GO:0006869 98 0.011
somitogenesis GO:0001756 69 0.011
pharynx development GO:0060465 1 0.011
inner ear receptor cell differentiation GO:0060113 61 0.011
ribonucleoside triphosphate metabolic process GO:0009199 220 0.011
purine containing compound catabolic process GO:0072523 213 0.011
generation of precursor metabolites and energy GO:0006091 103 0.011
response to peptide hormone GO:0043434 127 0.011
protein targeting GO:0006605 143 0.011
negative regulation of immune system process GO:0002683 209 0.011
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.011
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.011
forebrain neuron differentiation GO:0021879 52 0.011
oocyte construction GO:0007308 2 0.011
rhythmic process GO:0048511 174 0.011
macromolecule methylation GO:0043414 120 0.011
wound healing GO:0042060 157 0.011
steroid metabolic process GO:0008202 119 0.010
b cell differentiation GO:0030183 78 0.010
regulation of epithelial cell proliferation GO:0050678 141 0.010
ventral spinal cord development GO:0021517 48 0.010
cell cell junction organization GO:0045216 72 0.010
mitotic cell cycle GO:0000278 195 0.010
cellular divalent inorganic cation homeostasis GO:0072503 127 0.010
lymphocyte mediated immunity GO:0002449 139 0.010
neural tube closure GO:0001843 90 0.010
multi multicellular organism process GO:0044706 109 0.010
intrinsic apoptotic signaling pathway GO:0097193 132 0.010
oocyte axis specification GO:0007309 2 0.010
methylation GO:0032259 134 0.010
stem cell development GO:0048864 219 0.010
development of primary male sexual characteristics GO:0046546 88 0.010
cellular response to peptide hormone stimulus GO:0071375 92 0.010
cellular response to acid chemical GO:0071229 68 0.010
male sex differentiation GO:0046661 109 0.010
fatty acid metabolic process GO:0006631 121 0.010
positive regulation of binding GO:0051099 49 0.010
purine nucleotide catabolic process GO:0006195 211 0.010
spinal cord motor neuron differentiation GO:0021522 35 0.010
bmp signaling pathway GO:0030509 93 0.010
gonad morphogenesis GO:0035262 1 0.010
carboxylic acid biosynthetic process GO:0046394 86 0.010
regulation of hormone levels GO:0010817 211 0.010
retrograde transport endosome to golgi GO:0042147 2 0.010
regulation of nucleocytoplasmic transport GO:0046822 73 0.010
blood vessel morphogenesis GO:0048514 285 0.010
blastocyst development GO:0001824 80 0.010
response to oxidative stress GO:0006979 123 0.010
leukocyte migration GO:0050900 124 0.010

Pdzrn4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 0 0.024
disease of anatomical entity DOID:7 0 0.024
cardiovascular system disease DOID:1287 0 0.020
nervous system disease DOID:863 0 0.018
central nervous system disease DOID:331 0 0.015
cancer DOID:162 0 0.014
disease of cellular proliferation DOID:14566 0 0.014
organ system cancer DOID:0050686 0 0.014
disease of metabolism DOID:0014667 0 0.011