Mus musculus

25 known processes

Lgi3

leucine-rich repeat LGI family, member 3

(Aliases: AI841179,AW049851)

Lgi3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ion transmembrane transport GO:0034220 361 0.146
cation transport GO:0006812 399 0.144
cellular amine metabolic process GO:0044106 44 0.106
transmembrane transport GO:0055085 412 0.083
cation transmembrane transport GO:0098655 266 0.080
inorganic ion transmembrane transport GO:0098660 234 0.077
regulation of membrane potential GO:0042391 192 0.061
chemotaxis GO:0006935 247 0.060
cellular ketone metabolic process GO:0042180 84 0.059
inorganic cation transmembrane transport GO:0098662 207 0.059
cellular amino acid metabolic process GO:0006520 103 0.052
regulation of cellular amine metabolic process GO:0033238 20 0.051
sequestering of metal ion GO:0051238 19 0.048
synaptic transmission GO:0007268 329 0.047
amine metabolic process GO:0009308 45 0.045
nucleobase containing small molecule metabolic process GO:0055086 352 0.039
sequestering of calcium ion GO:0051208 18 0.038
regulation of cellular amino acid metabolic process GO:0006521 5 0.037
regulation of neuron differentiation GO:0045664 281 0.036
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.035
positive regulation of nervous system development GO:0051962 221 0.035
calcium ion transport GO:0006816 159 0.034
cell adhesion GO:0007155 329 0.034
anion transport GO:0006820 177 0.033
cellular homeostasis GO:0019725 240 0.033
regulation of ion transport GO:0043269 215 0.033
axonogenesis GO:0007409 274 0.033
action potential GO:0001508 78 0.032
regulation of cellular ketone metabolic process GO:0010565 66 0.031
regulation of organelle organization GO:0033043 289 0.031
divalent inorganic cation transport GO:0072511 178 0.031
forebrain development GO:0030900 302 0.030
single organism cell adhesion GO:0098602 156 0.030
nucleotide metabolic process GO:0009117 332 0.030
cation homeostasis GO:0055080 212 0.030
intracellular protein transport GO:0006886 204 0.029
cytoplasmic transport GO:0016482 234 0.029
maintenance of location GO:0051235 89 0.029
exocytosis GO:0006887 121 0.029
transmission of nerve impulse GO:0019226 76 0.028
organonitrogen compound biosynthetic process GO:1901566 192 0.028
membrane organization GO:0061024 245 0.027
developmental maturation GO:0021700 193 0.027
organonitrogen compound catabolic process GO:1901565 264 0.027
nucleoside phosphate metabolic process GO:0006753 338 0.026
cognition GO:0050890 149 0.026
regulation of cell migration GO:0030334 219 0.026
regulation of homeostatic process GO:0032844 182 0.025
ribose phosphate metabolic process GO:0019693 291 0.025
regulation of neuron projection development GO:0010975 169 0.025
regulation of cell projection organization GO:0031344 206 0.025
anion transmembrane transport GO:0098656 71 0.025
wnt signaling pathway GO:0016055 188 0.025
lateral inhibition GO:0046331 1 0.025
organic anion transport GO:0015711 137 0.025
muscle cell differentiation GO:0042692 261 0.025
male gamete generation GO:0048232 285 0.025
positive regulation of cell development GO:0010720 237 0.025
sensory perception GO:0007600 245 0.024
organic cyclic compound catabolic process GO:1901361 295 0.024
positive regulation of cellular amine metabolic process GO:0033240 5 0.024
cellular lipid metabolic process GO:0044255 323 0.024
neuronal action potential GO:0019228 54 0.023
multicellular organismal signaling GO:0035637 91 0.023
regulation of cell cycle GO:0051726 281 0.023
nucleoside metabolic process GO:0009116 246 0.023
locomotory behavior GO:0007626 195 0.023
angiogenesis GO:0001525 201 0.023
divalent metal ion transport GO:0070838 172 0.023
neuron apoptotic process GO:0051402 142 0.023
g protein coupled receptor signaling pathway GO:0007186 243 0.022
carbohydrate derivative biosynthetic process GO:1901137 183 0.022
purine ribonucleoside catabolic process GO:0046130 205 0.022
positive regulation of protein modification process GO:0031401 299 0.022
epithelial cell development GO:0002064 159 0.022
cellular chemical homeostasis GO:0055082 215 0.022
circulatory system process GO:0003013 197 0.022
microtubule based process GO:0007017 236 0.021
cellular divalent inorganic cation homeostasis GO:0072503 127 0.021
negative regulation of molecular function GO:0044092 258 0.021
regulation of hydrolase activity GO:0051336 246 0.021
cell type specific apoptotic process GO:0097285 268 0.021
peptidyl amino acid modification GO:0018193 336 0.021
leukocyte migration GO:0050900 124 0.021
cellular ion homeostasis GO:0006873 165 0.021
organic hydroxy compound metabolic process GO:1901615 203 0.021
spermatogenesis GO:0007283 284 0.021
cellular nitrogen compound catabolic process GO:0044270 280 0.021
regulation of cellular catabolic process GO:0031329 242 0.020
purine ribonucleotide metabolic process GO:0009150 290 0.020
response to growth factor GO:0070848 198 0.020
purine containing compound metabolic process GO:0072521 311 0.020
regulation of cell motility GO:2000145 236 0.020
small gtpase mediated signal transduction GO:0007264 97 0.020
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.020
ribonucleotide catabolic process GO:0009261 208 0.020
purine ribonucleoside metabolic process GO:0046128 241 0.020
negative regulation of cell proliferation GO:0008285 296 0.020
regulation of ion transmembrane transport GO:0034765 119 0.020
regulation of neuron death GO:1901214 134 0.020
nitrogen compound transport GO:0071705 271 0.019
regulation of ion homeostasis GO:2000021 64 0.019
calcium ion transmembrane transport GO:0070588 85 0.019
cell chemotaxis GO:0060326 81 0.019
heterocycle catabolic process GO:0046700 280 0.019
neuron death GO:0070997 154 0.019
nucleoside phosphate catabolic process GO:1901292 222 0.019
ras protein signal transduction GO:0007265 77 0.019
positive regulation of neuron differentiation GO:0045666 141 0.019
sodium ion transmembrane transport GO:0035725 49 0.019
camera type eye development GO:0043010 266 0.019
protein localization to organelle GO:0033365 185 0.019
axon guidance GO:0007411 141 0.019
oxidation reduction process GO:0055114 342 0.019
negative regulation of cell development GO:0010721 169 0.019
aromatic compound catabolic process GO:0019439 286 0.019
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.019
t cell activation GO:0042110 289 0.018
macromolecule catabolic process GO:0009057 281 0.018
reactive nitrogen species metabolic process GO:2001057 0 0.018
positive regulation of protein phosphorylation GO:0001934 242 0.018
cytokine production GO:0001816 319 0.018
apoptotic signaling pathway GO:0097190 306 0.018
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.018
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.018
reactive oxygen species metabolic process GO:0072593 84 0.018
ribonucleoside metabolic process GO:0009119 245 0.018
glycosyl compound metabolic process GO:1901657 246 0.018
blood vessel morphogenesis GO:0048514 285 0.018
protein catabolic process GO:0030163 221 0.018
glycerophospholipid metabolic process GO:0006650 71 0.018
purine ribonucleotide catabolic process GO:0009154 208 0.018
actin filament organization GO:0007015 113 0.018
cellular metal ion homeostasis GO:0006875 151 0.018
purine nucleotide metabolic process GO:0006163 302 0.017
gland development GO:0048732 330 0.017
negative regulation of phosphorylation GO:0042326 166 0.017
mesodermal cell migration GO:0008078 4 0.017
rap protein signal transduction GO:0032486 3 0.017
regulation of transmembrane transport GO:0034762 128 0.017
sodium ion transport GO:0006814 73 0.017
carbohydrate metabolic process GO:0005975 230 0.017
purine nucleoside catabolic process GO:0006152 205 0.017
dephosphorylation GO:0016311 129 0.017
negative regulation of cellular amine metabolic process GO:0033239 1 0.017
neuromuscular process GO:0050905 99 0.017
urogenital system development GO:0001655 261 0.017
negative regulation of protein metabolic process GO:0051248 282 0.017
reactive oxygen species biosynthetic process GO:1903409 8 0.017
purine nucleoside metabolic process GO:0042278 241 0.016
phospholipid metabolic process GO:0006644 87 0.016
metal ion homeostasis GO:0055065 189 0.016
cellular response to growth factor stimulus GO:0071363 197 0.016
ribonucleotide metabolic process GO:0009259 291 0.016
regulation of wnt signaling pathway GO:0030111 123 0.016
regulation of calcium ion transport GO:0051924 69 0.016
regulation of metal ion transport GO:0010959 106 0.016
spermatid differentiation GO:0048515 115 0.016
regulation of purine nucleotide metabolic process GO:1900542 169 0.016
regulation of secretion GO:0051046 274 0.016
epithelial tube morphogenesis GO:0060562 303 0.016
positive regulation of cell death GO:0010942 224 0.016
cell maturation GO:0048469 127 0.016
regulation of system process GO:0044057 200 0.016
regulation of ion transmembrane transporter activity GO:0032412 54 0.016
leukocyte chemotaxis GO:0030595 69 0.016
myotube differentiation GO:0014902 105 0.016
carboxylic acid transport GO:0046942 100 0.016
cell growth GO:0016049 130 0.016
positive regulation of organelle organization GO:0010638 128 0.016
cellular response to cytokine stimulus GO:0071345 189 0.016
calcium ion homeostasis GO:0055074 127 0.016
positive regulation of apoptotic process GO:0043065 217 0.016
ribonucleoside triphosphate metabolic process GO:0009199 220 0.016
regulation of mapk cascade GO:0043408 248 0.016
activation of immune response GO:0002253 138 0.015
lipid biosynthetic process GO:0008610 179 0.015
immune effector process GO:0002252 321 0.015
innate immune response GO:0045087 157 0.015
protein targeting GO:0006605 143 0.015
regulation of synaptic plasticity GO:0048167 87 0.015
posttranscriptional regulation of gene expression GO:0010608 155 0.015
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.015
organophosphate catabolic process GO:0046434 232 0.015
regulation of postsynaptic membrane potential GO:0060078 48 0.015
purine nucleotide catabolic process GO:0006195 211 0.015
establishment of organelle localization GO:0051656 122 0.015
regulation of intracellular transport GO:0032386 159 0.015
regulation of cell adhesion GO:0030155 154 0.015
negative regulation of neuron apoptotic process GO:0043524 92 0.015
purine nucleoside triphosphate catabolic process GO:0009146 203 0.015
regulation of protein localization GO:0032880 231 0.015
compound eye development GO:0048749 1 0.015
regulation of cytokine production GO:0001817 266 0.015
carbohydrate derivative catabolic process GO:1901136 231 0.015
nucleoside triphosphate metabolic process GO:0009141 230 0.015
cell recognition GO:0008037 83 0.014
regulation of defense response GO:0031347 233 0.014
regulation of neuron apoptotic process GO:0043523 122 0.014
cell junction maintenance GO:0034331 4 0.014
heart morphogenesis GO:0003007 178 0.014
regulation of establishment of protein localization GO:0070201 181 0.014
regulation of canonical wnt signaling pathway GO:0060828 82 0.014
regulation of proteolysis GO:0030162 164 0.014
response to inorganic substance GO:0010035 96 0.014
negative regulation of multi organism process GO:0043901 68 0.014
nucleotide catabolic process GO:0009166 217 0.014
regulation of kinase activity GO:0043549 249 0.014
negative regulation of cellular component organization GO:0051129 194 0.014
developmental growth involved in morphogenesis GO:0060560 138 0.014
regulation of secretion by cell GO:1903530 249 0.014
regulation of cellular component biogenesis GO:0044087 181 0.013
response to organonitrogen compound GO:0010243 246 0.013
regulation of protein kinase activity GO:0045859 232 0.013
regulation of cell activation GO:0050865 289 0.013
cellular response to organonitrogen compound GO:0071417 145 0.013
regulation of cellular response to growth factor stimulus GO:0090287 82 0.013
rho protein signal transduction GO:0007266 32 0.013
regulation of mitotic cell cycle GO:0007346 126 0.013
striated muscle tissue development GO:0014706 293 0.013
glial cell differentiation GO:0010001 131 0.013
regulation of multi organism process GO:0043900 111 0.013
neuron neuron synaptic transmission GO:0007270 69 0.013
purine containing compound catabolic process GO:0072523 213 0.013
inorganic anion transport GO:0015698 43 0.013
ribonucleoside catabolic process GO:0042454 206 0.013
glycoprotein biosynthetic process GO:0009101 89 0.013
positive regulation of transferase activity GO:0051347 167 0.013
learning or memory GO:0007611 148 0.013
sensory organ morphogenesis GO:0090596 242 0.013
regulation of actin filament based process GO:0032970 99 0.013
protein modification by small protein conjugation or removal GO:0070647 207 0.013
endocytosis GO:0006897 168 0.013
rna interference GO:0016246 2 0.013
positive regulation of programmed cell death GO:0043068 218 0.013
ossification GO:0001503 216 0.013
axon ensheathment GO:0008366 76 0.013
hematopoietic progenitor cell differentiation GO:0002244 143 0.013
nuclear transport GO:0051169 139 0.013
positive regulation of secretion GO:0051047 130 0.013
organic acid transport GO:0015849 101 0.013
positive regulation of mapk cascade GO:0043410 170 0.013
protein modification by small protein conjugation GO:0032446 187 0.013
ear development GO:0043583 200 0.013
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.013
negative regulation of cellular protein metabolic process GO:0032269 247 0.013
regulation of nucleotide metabolic process GO:0006140 169 0.013
nucleoside catabolic process GO:0009164 206 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.013
regulation of reactive oxygen species metabolic process GO:2000377 40 0.013
oocyte construction GO:0007308 2 0.013
cellular response to lipid GO:0071396 145 0.012
protein localization to membrane GO:0072657 108 0.012
neural precursor cell proliferation GO:0061351 121 0.012
rac protein signal transduction GO:0016601 13 0.012
ribonucleoside triphosphate catabolic process GO:0009203 199 0.012
endomembrane system organization GO:0010256 147 0.012
blood circulation GO:0008015 195 0.012
intracellular mrna localization GO:0008298 4 0.012
regulation of protein catabolic process GO:0042176 108 0.012
oocyte axis specification GO:0007309 2 0.012
glycoprotein metabolic process GO:0009100 116 0.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.012
wound healing GO:0042060 157 0.012
cell substrate adhesion GO:0031589 130 0.012
response to radiation GO:0009314 165 0.012
multicellular organismal response to stress GO:0033555 62 0.012
substantia nigra development GO:0021762 2 0.012
cellular response to oxidative stress GO:0034599 76 0.012
regulation of binding GO:0051098 111 0.012
positive regulation of protein kinase activity GO:0045860 144 0.012
myelination GO:0042552 74 0.012
dorsal ventral axon guidance GO:0033563 3 0.012
leukocyte activation involved in immune response GO:0002366 126 0.012
positive regulation of defense response GO:0031349 124 0.012
dna metabolic process GO:0006259 303 0.012
engulfment of apoptotic cell GO:0043652 3 0.012
positive regulation of immune effector process GO:0002699 107 0.012
response to oxidative stress GO:0006979 123 0.012
regulation of response to wounding GO:1903034 189 0.012
neuron migration GO:0001764 122 0.012
regulation of renal sodium excretion GO:0035813 3 0.012
cellular calcium ion homeostasis GO:0006874 119 0.012
organelle localization GO:0051640 179 0.012
inflammatory response GO:0006954 244 0.012
organelle fission GO:0048285 170 0.012
ensheathment of neurons GO:0007272 76 0.012
alcohol metabolic process GO:0006066 116 0.011
protein ubiquitination GO:0016567 171 0.011
homeostasis of number of cells GO:0048872 210 0.011
negative regulation of neuron death GO:1901215 98 0.011
skeletal muscle organ development GO:0060538 163 0.011
regulation of cytoskeleton organization GO:0051493 122 0.011
mitotic cell cycle GO:0000278 195 0.011
telencephalon development GO:0021537 186 0.011
actin mediated cell contraction GO:0070252 15 0.011
amino acid transport GO:0006865 61 0.011
regulation of cellular response to stress GO:0080135 159 0.011
response to organic cyclic compound GO:0014070 198 0.011
positive regulation of cell motility GO:2000147 116 0.011
immune response activating signal transduction GO:0002757 116 0.011
negative regulation of phosphate metabolic process GO:0045936 184 0.011
nucleocytoplasmic transport GO:0006913 139 0.011
regulation of angiogenesis GO:0045765 81 0.011
nucleoside triphosphate catabolic process GO:0009143 205 0.011
cell activation involved in immune response GO:0002263 126 0.011
regulation of transferase activity GO:0051338 263 0.011
actin cytoskeleton organization GO:0030036 220 0.011
organophosphate biosynthetic process GO:0090407 122 0.011
positive regulation of hydrolase activity GO:0051345 148 0.011
positive regulation of cellular catabolic process GO:0031331 148 0.011
negative regulation of immune system process GO:0002683 209 0.011
tissue remodeling GO:0048771 102 0.011
regulation of cellular component size GO:0032535 121 0.011
monocarboxylic acid metabolic process GO:0032787 191 0.011
purine nucleoside triphosphate metabolic process GO:0009144 226 0.011
positive regulation of nucleoside metabolic process GO:0045979 91 0.011
sensory perception of mechanical stimulus GO:0050954 107 0.011
regulation of cell cycle process GO:0010564 160 0.011
fertilization GO:0009566 127 0.011
single organismal cell cell adhesion GO:0016337 131 0.011
germ cell development GO:0007281 185 0.011
epidermis development GO:0008544 187 0.011
glycosyl compound catabolic process GO:1901658 206 0.011
stem cell development GO:0048864 219 0.011
mapk cascade GO:0000165 281 0.011
canonical wnt signaling pathway GO:0060070 130 0.011
stem cell differentiation GO:0048863 268 0.011
positive regulation of cell migration GO:0030335 109 0.011
leukocyte differentiation GO:0002521 342 0.011
fat cell differentiation GO:0045444 160 0.011
divalent inorganic cation homeostasis GO:0072507 138 0.011
cellular macromolecule catabolic process GO:0044265 206 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.011
actin filament based movement GO:0030048 23 0.011
negative regulation of phosphorus metabolic process GO:0010563 184 0.011
cardiac muscle cell contraction GO:0086003 7 0.011
myeloid cell differentiation GO:0030099 233 0.011
regulation of nucleoside metabolic process GO:0009118 130 0.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.011
pallium development GO:0021543 120 0.010
plasma membrane organization GO:0007009 90 0.010
regulation of cytoplasmic transport GO:1903649 112 0.010
morphogenesis of embryonic epithelium GO:0016331 159 0.010
myeloid leukocyte migration GO:0097529 57 0.010
leukocyte mediated immunity GO:0002443 174 0.010
response to lipopolysaccharide GO:0032496 128 0.010
protein localization to nucleus GO:0034504 121 0.010
regulation of lymphocyte activation GO:0051249 240 0.010
regulation of anatomical structure size GO:0090066 178 0.010
skeletal system development GO:0001501 356 0.010
ameboidal type cell migration GO:0001667 128 0.010

Lgi3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 0 0.030
disease of anatomical entity DOID:7 0 0.030
nervous system disease DOID:863 0 0.030
disease of metabolism DOID:0014667 0 0.013
inherited metabolic disorder DOID:655 0 0.012
brain disease DOID:936 0 0.012
sensory system disease DOID:0050155 0 0.012
eye and adnexa disease DOID:1492 0 0.012
eye disease DOID:5614 0 0.012
retinal disease DOID:5679 0 0.010
retinal degeneration DOID:8466 0 0.010