Mus musculus

0 known processes

Mrgpra2a

MAS-related GPR, member A2A

(Aliases: MGC73535)

Mrgpra2a biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
leukocyte activation involved in immune response GO:0002366 126 0.115
leukocyte mediated immunity GO:0002443 174 0.101
regulation of cellular amine metabolic process GO:0033238 20 0.096
defense response to other organism GO:0098542 197 0.090
immune effector process GO:0002252 321 0.084
g protein coupled receptor signaling pathway GO:0007186 243 0.084
Human Mouse
interspecies interaction between organisms GO:0044419 83 0.083
inflammatory response GO:0006954 244 0.078
cell surface pattern recognition receptor signaling pathway GO:0002752 2 0.070
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.069
production of molecular mediator of immune response GO:0002440 103 0.069
regulation of reactive oxygen species metabolic process GO:2000377 40 0.067
regulation of cellular ketone metabolic process GO:0010565 66 0.065
chemotaxis GO:0006935 247 0.065
positive regulation of immune effector process GO:0002699 107 0.061
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.061
defense response to bacterium GO:0042742 119 0.060
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.058
cellular amino acid metabolic process GO:0006520 103 0.058
cell killing GO:0001906 67 0.056
cytokine production GO:0001816 319 0.056
regulation of cellular amino acid metabolic process GO:0006521 5 0.050
reactive oxygen species biosynthetic process GO:1903409 8 0.048
muscle cell differentiation GO:0042692 261 0.047
regulation of protein kinase activity GO:0045859 232 0.047
positive regulation of cellular amine metabolic process GO:0033240 5 0.047
reactive nitrogen species metabolic process GO:2001057 0 0.044
detection of fungus GO:0016046 2 0.044
response to molecule of bacterial origin GO:0002237 143 0.043
reactive oxygen species metabolic process GO:0072593 84 0.043
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.043
cellular amine metabolic process GO:0044106 44 0.041
cell activation involved in immune response GO:0002263 126 0.040
regulation of transferase activity GO:0051338 263 0.039
negative regulation of cellular protein metabolic process GO:0032269 247 0.039
cellular response to peptidoglycan GO:0071224 4 0.039
innate immune response GO:0045087 157 0.039
cytokine production involved in immune response GO:0002367 34 0.039
regulation of cell motility GO:2000145 236 0.038
wound healing GO:0042060 157 0.036
cellular ketone metabolic process GO:0042180 84 0.036
negative regulation of molecular function GO:0044092 258 0.035
t cell activation GO:0042110 289 0.035
cellular response to organonitrogen compound GO:0071417 145 0.034
innate immune response activating cell surface receptor signaling pathway GO:0002220 4 0.032
nitrogen compound transport GO:0071705 271 0.032
regulation of lymphocyte mediated immunity GO:0002706 84 0.031
regulation of hormone levels GO:0010817 211 0.030
positive regulation of protein phosphorylation GO:0001934 242 0.030
regulation of defense response GO:0031347 233 0.029
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.029
regulation of leukocyte mediated immunity GO:0002703 104 0.029
negative regulation of serotonin secretion GO:0014063 2 0.029
hematopoietic progenitor cell differentiation GO:0002244 143 0.029
Mouse
regulation of response to wounding GO:1903034 189 0.028
response to lipopolysaccharide GO:0032496 128 0.028
cellular response to cytokine stimulus GO:0071345 189 0.028
positive regulation of transferase activity GO:0051347 167 0.027
leukocyte differentiation GO:0002521 342 0.027
regulation of secretion GO:0051046 274 0.027
protein modification by small protein conjugation GO:0032446 187 0.026
interferon gamma production GO:0032609 67 0.026
positive regulation of defense response GO:0031349 124 0.026
regulation of lymphocyte activation GO:0051249 240 0.026
leukocyte mediated cytotoxicity GO:0001909 62 0.026
regulation of cell cycle GO:0051726 281 0.025
Human
regulation of apoptotic signaling pathway GO:2001233 197 0.025
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.025
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.025
apoptotic signaling pathway GO:0097190 306 0.024
activation of innate immune response GO:0002218 56 0.024
cytokine metabolic process GO:0042107 71 0.024
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.024
macromolecule catabolic process GO:0009057 281 0.023
response to acid chemical GO:0001101 111 0.023
cellular response to hormone stimulus GO:0032870 150 0.023
peptidyl amino acid modification GO:0018193 336 0.023
phagocytosis GO:0006909 66 0.022
regulation of vesicle mediated transport GO:0060627 139 0.022
stimulatory c type lectin receptor signaling pathway GO:0002223 2 0.022
neutrophil chemotaxis GO:0030593 36 0.022
protein secretion GO:0009306 111 0.022
cell chemotaxis GO:0060326 81 0.022
cation transport GO:0006812 399 0.022
negative regulation of protein metabolic process GO:0051248 282 0.022
cellular macromolecule catabolic process GO:0044265 206 0.021
protein modification by small protein conjugation or removal GO:0070647 207 0.021
endocytosis GO:0006897 168 0.021
divalent inorganic cation transport GO:0072511 178 0.021
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.020
response to organonitrogen compound GO:0010243 246 0.020
cytokine secretion GO:0050663 72 0.020
membrane organization GO:0061024 245 0.020
response to oxidative stress GO:0006979 123 0.020
positive regulation of protein modification process GO:0031401 299 0.020
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.020
protein ubiquitination GO:0016567 171 0.019
action potential GO:0001508 78 0.019
regulation of proteolysis GO:0030162 164 0.019
positive regulation of cytokine production GO:0001819 174 0.019
activation of nf kappab inducing kinase activity GO:0007250 4 0.019
skeletal muscle organ development GO:0060538 163 0.019
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.019
negative regulation of immune system process GO:0002683 209 0.019
regulation of cell activation GO:0050865 289 0.019
regulation of multi organism process GO:0043900 111 0.018
response to peptide GO:1901652 136 0.018
organic hydroxy compound metabolic process GO:1901615 203 0.018
cellular response to lipid GO:0071396 145 0.018
lymphocyte mediated immunity GO:0002449 139 0.018
sensory perception GO:0007600 245 0.018
myeloid cell differentiation GO:0030099 233 0.018
protein processing GO:0016485 163 0.018
response to organic cyclic compound GO:0014070 198 0.018
transmission of nerve impulse GO:0019226 76 0.018
defense response to gram positive bacterium GO:0050830 50 0.018
amine metabolic process GO:0009308 45 0.018
lymphocyte activation involved in immune response GO:0002285 93 0.018
multicellular organismal homeostasis GO:0048871 164 0.018
positive regulation of protein kinase activity GO:0045860 144 0.017
regulation of protein processing GO:0070613 96 0.017
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.017
protein catabolic process GO:0030163 221 0.017
tissue homeostasis GO:0001894 115 0.017
natural killer cell activation GO:0030101 44 0.017
cellular lipid metabolic process GO:0044255 323 0.017
organic cyclic compound catabolic process GO:1901361 295 0.017
regulation of body fluid levels GO:0050878 162 0.017
cellular response to lipopolysaccharide GO:0071222 77 0.016
posttranscriptional regulation of gene expression GO:0010608 155 0.016
regulation of kinase activity GO:0043549 249 0.016
positive regulation of protein transport GO:0051222 93 0.016
growth of symbiont in host GO:0044117 23 0.016
muscle tissue development GO:0060537 308 0.016
ras protein signal transduction GO:0007265 77 0.016
regulation of protein localization GO:0032880 231 0.016
regulation of cell migration GO:0030334 219 0.016
cell adhesion GO:0007155 329 0.016
regulation of membrane potential GO:0042391 192 0.016
regulation of chemokine production GO:0032642 30 0.016
regulation of cell projection organization GO:0031344 206 0.015
regulation of endopeptidase activity GO:0052548 89 0.015
myeloid leukocyte differentiation GO:0002573 119 0.015
endomembrane system organization GO:0010256 147 0.015
negative regulation of mast cell degranulation GO:0043305 4 0.015
interleukin 18 production GO:0032621 4 0.015
regulation of cytokine production GO:0001817 266 0.015
regulation of protein catabolic process GO:0042176 108 0.015
neuronal action potential GO:0019228 54 0.015
negative regulation of growth GO:0045926 99 0.015
negative regulation of intracellular signal transduction GO:1902532 167 0.015
aromatic compound catabolic process GO:0019439 286 0.015
regulation of protein serine threonine kinase activity GO:0071900 157 0.015
regulation of interferon gamma production GO:0032649 57 0.015
urogenital system development GO:0001655 261 0.014
amide transport GO:0042886 138 0.014
toll like receptor signaling pathway GO:0002224 38 0.014
negative regulation of immune effector process GO:0002698 55 0.014
microtubule based movement GO:0007018 84 0.014
negative regulation of cytokine production GO:0001818 84 0.014
cellular response to molecule of fungal origin GO:0071226 2 0.014
cellular response to biotic stimulus GO:0071216 92 0.014
negative regulation of multi organism process GO:0043901 68 0.014
sensory organ morphogenesis GO:0090596 242 0.014
negative regulation of cellular component organization GO:0051129 194 0.014
interleukin 6 production GO:0032635 58 0.014
hormone metabolic process GO:0042445 86 0.014
innate immune response activating signal transduction GO:0002758 50 0.014
defense response to virus GO:0051607 68 0.014
leukocyte migration GO:0050900 124 0.014
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.014
anatomical structure homeostasis GO:0060249 145 0.014
neutrophil migration GO:1990266 37 0.013
connective tissue development GO:0061448 179 0.013
killing of cells of other organism GO:0031640 13 0.013
mapk cascade GO:0000165 281 0.013
regulation of inflammatory response GO:0050727 147 0.013
regulation of protein maturation GO:1903317 96 0.013
protein localization to organelle GO:0033365 185 0.013
regulation of secretion by cell GO:1903530 249 0.013
skeletal system development GO:0001501 356 0.013
myeloid leukocyte mediated immunity GO:0002444 42 0.013
organonitrogen compound biosynthetic process GO:1901566 192 0.013
nucleobase containing small molecule metabolic process GO:0055086 352 0.013
cellular chemical homeostasis GO:0055082 215 0.013
single organism cell adhesion GO:0098602 156 0.013
cation homeostasis GO:0055080 212 0.013
myeloid leukocyte migration GO:0097529 57 0.013
negative regulation of phagocytosis GO:0050765 4 0.013
regulation of establishment of protein localization GO:0070201 181 0.013
cellular response to organic cyclic compound GO:0071407 87 0.013
single organismal cell cell adhesion GO:0016337 131 0.013
hormone secretion GO:0046879 128 0.013
cation transmembrane transport GO:0098655 266 0.013
intracellular protein transport GO:0006886 204 0.012
cartilage development GO:0051216 140 0.012
peptidyl tyrosine phosphorylation GO:0018108 143 0.012
activation of mapk activity involved in innate immune response GO:0035419 2 0.012
circulatory system process GO:0003013 197 0.012
cellular response to molecule of bacterial origin GO:0071219 83 0.012
positive regulation of cell motility GO:2000147 116 0.012
leukocyte proliferation GO:0070661 172 0.012
gliogenesis GO:0042063 141 0.012
ameboidal type cell migration GO:0001667 128 0.012
negative regulation of cell proliferation GO:0008285 296 0.012
muscle cell development GO:0055001 133 0.012
synaptic transmission GO:0007268 329 0.012
Mouse
i kappab kinase nf kappab signaling GO:0007249 85 0.012
immunoglobulin transcytosis in epithelial cells GO:0002414 2 0.012
cellular response to peptide hormone stimulus GO:0071375 92 0.011
microtubule based process GO:0007017 236 0.011
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.011
oocyte axis specification GO:0007309 2 0.011
blood circulation GO:0008015 195 0.011
response to extracellular stimulus GO:0009991 127 0.011
cell maturation GO:0048469 127 0.011
alcohol metabolic process GO:0006066 116 0.011
leukocyte chemotaxis GO:0030595 69 0.011
positive regulation of kinase activity GO:0033674 155 0.011
cell type specific apoptotic process GO:0097285 268 0.011
oxidation reduction process GO:0055114 342 0.011
cytoplasmic transport GO:0016482 234 0.011
axon ensheathment GO:0008366 76 0.011
neutrophil mediated immunity GO:0002446 19 0.011
negative regulation of response to wounding GO:1903035 77 0.011
immune response regulating signaling pathway GO:0002764 125 0.011
cellular response to oxidative stress GO:0034599 76 0.011
multicellular organismal signaling GO:0035637 91 0.011
response to growth factor GO:0070848 198 0.011
regulation of cellular response to stress GO:0080135 159 0.011
regulation of peptidase activity GO:0052547 96 0.011
nuclear transport GO:0051169 139 0.011
interleukin 27 mediated signaling pathway GO:0070106 1 0.011
axonogenesis GO:0007409 274 0.010
peptide transport GO:0015833 133 0.010
positive regulation of toll like receptor 9 signaling pathway GO:0034165 2 0.010
regulation of cellular catabolic process GO:0031329 242 0.010
regulation of cellular response to insulin stimulus GO:1900076 30 0.010
rho protein signal transduction GO:0007266 32 0.010
regulation of phagocytosis GO:0050764 33 0.010
purine containing compound metabolic process GO:0072521 311 0.010
negative regulation of lymphocyte activation GO:0051250 91 0.010
positive regulation of protein ubiquitination GO:0031398 27 0.010
cellular response to insulin stimulus GO:0032869 78 0.010
inflammatory response to antigenic stimulus GO:0002437 30 0.010

Mrgpra2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.023
disease of anatomical entity DOID:7 0 0.023
cancer DOID:162 0 0.022
disease of cellular proliferation DOID:14566 0 0.022
organ system cancer DOID:0050686 0 0.022
hematopoietic system disease DOID:74 0 0.021
disease of metabolism DOID:0014667 0 0.012