Mus musculus

214 known processes

Igf2

insulin-like growth factor 2

(Aliases: Igf-2,Igf-II,AL033362,Mpr,Peg2,M6pr)

Igf2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
epithelial tube morphogenesis GO:0060562 303 0.795
Mouse
myotube differentiation GO:0014902 105 0.678
Mouse
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.651
cell adhesion GO:0007155 329 0.639
regulation of glucan biosynthetic process GO:0010962 7 0.633
peptidyl tyrosine phosphorylation GO:0018108 143 0.623
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.612
ameboidal type cell migration GO:0001667 128 0.562
sensory organ morphogenesis GO:0090596 242 0.493
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.468
response to organonitrogen compound GO:0010243 246 0.450
purine nucleoside triphosphate metabolic process GO:0009144 226 0.446
positive regulation of cellular amine metabolic process GO:0033240 5 0.443
sensory perception of umami taste GO:0050917 4 0.441
regulation of circadian sleep wake cycle GO:0042749 3 0.421
myeloid cell differentiation GO:0030099 233 0.389
negative regulation of phosphorus metabolic process GO:0010563 184 0.388
Mouse
cellular response to peptide hormone stimulus GO:0071375 92 0.377
glucose metabolic process GO:0006006 92 0.375
angiogenesis GO:0001525 201 0.374
regulation of nucleotide catabolic process GO:0030811 122 0.371
regulation of cellular catabolic process GO:0031329 242 0.369
positive regulation of leukocyte differentiation GO:1902107 86 0.354
cellular response to growth factor stimulus GO:0071363 197 0.349
divalent inorganic cation homeostasis GO:0072507 138 0.343
regulation of glycogen metabolic process GO:0070873 13 0.339
leukocyte differentiation GO:0002521 342 0.335
chemotaxis GO:0006935 247 0.334
regulation of heart contraction GO:0008016 77 0.329
single organism cell adhesion GO:0098602 156 0.325
regulation of nucleoside metabolic process GO:0009118 130 0.315
regulation of polysaccharide metabolic process GO:0032881 13 0.310
heart contraction GO:0060047 93 0.305
hexose transport GO:0008645 56 0.305
gland development GO:0048732 330 0.305
Mouse
cellular chemical homeostasis GO:0055082 215 0.301
inositol lipid mediated signaling GO:0048017 41 0.299
Mouse
regulation of ion transport GO:0043269 215 0.298
kidney development GO:0001822 213 0.297
Zebrafish
macromolecule catabolic process GO:0009057 281 0.294
neuron maturation GO:0042551 29 0.289
cellular amino acid metabolic process GO:0006520 103 0.285
mapk cascade GO:0000165 281 0.283
Human Mouse
negative regulation of phosphorylation GO:0042326 166 0.282
Mouse
camera type eye development GO:0043010 266 0.278
regulation of feeding behavior GO:0060259 3 0.277
regulation of cell migration GO:0030334 219 0.273
gtp catabolic process GO:0006184 143 0.270
regulation of hormone levels GO:0010817 211 0.265
Rat
striated muscle tissue development GO:0014706 293 0.263
muscle cell development GO:0055001 133 0.263
energy reserve metabolic process GO:0006112 39 0.263
cellular response to peptide GO:1901653 92 0.263
regulation of cell growth GO:0001558 91 0.258
negative regulation of phosphate metabolic process GO:0045936 184 0.258
Mouse
embryonic organ morphogenesis GO:0048562 276 0.254
negative regulation of kinase activity GO:0033673 81 0.251
heart morphogenesis GO:0003007 178 0.245
cognition GO:0050890 149 0.245
Rat
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.244
muscle cell differentiation GO:0042692 261 0.242
response to alkaloid GO:0043279 34 0.241
Rat
negative regulation of glycogen biosynthetic process GO:0045719 1 0.238
retina development in camera type eye GO:0060041 119 0.234
negative regulation of cell proliferation GO:0008285 296 0.233
Mouse
central nervous system neuron differentiation GO:0021953 162 0.231
cellular metal ion homeostasis GO:0006875 151 0.223
cellular amine metabolic process GO:0044106 44 0.222
negative regulation of cellular protein metabolic process GO:0032269 247 0.221
purine nucleoside metabolic process GO:0042278 241 0.220
nucleoside triphosphate catabolic process GO:0009143 205 0.219
negative regulation of transferase activity GO:0051348 85 0.218
ras protein signal transduction GO:0007265 77 0.218
regulation of transferase activity GO:0051338 263 0.215
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.214
cellular response to insulin stimulus GO:0032869 78 0.214
oxidation reduction process GO:0055114 342 0.211
response to extracellular stimulus GO:0009991 127 0.210
Rat
multicellular organism growth GO:0035264 161 0.210
Mouse
wnt signaling pathway GO:0016055 188 0.208
Mouse
phosphatidylinositol mediated signaling GO:0048015 41 0.207
Mouse
negative regulation of epithelial cell proliferation GO:0050680 64 0.207
regulation of actin filament based process GO:0032970 99 0.207
heterocycle catabolic process GO:0046700 280 0.204
regulation of cell motility GO:2000145 236 0.204
organelle fission GO:0048285 170 0.202
Human
response to growth factor GO:0070848 198 0.202
insulin like growth factor receptor signaling pathway GO:0048009 21 0.202
Mouse
purine ribonucleotide metabolic process GO:0009150 290 0.201
urogenital system development GO:0001655 261 0.196
Zebrafish Mouse
gtp metabolic process GO:0046039 144 0.196
nucleotide metabolic process GO:0009117 332 0.196
mesodermal cell migration GO:0008078 4 0.196
purine ribonucleotide catabolic process GO:0009154 208 0.195
nucleoside phosphate metabolic process GO:0006753 338 0.191
regulation of cellular response to growth factor stimulus GO:0090287 82 0.188
regulation of cellular ketone metabolic process GO:0010565 66 0.187
purine nucleotide catabolic process GO:0006195 211 0.187
cell growth GO:0016049 130 0.185
metal ion homeostasis GO:0055065 189 0.184
glycogen biosynthetic process GO:0005978 14 0.181
small gtpase mediated signal transduction GO:0007264 97 0.179
cellular response to organonitrogen compound GO:0071417 145 0.179
epidermis development GO:0008544 187 0.177
regulation of membrane potential GO:0042391 192 0.177
regulation of kinase activity GO:0043549 249 0.177
response to ph GO:0009268 14 0.175
purine nucleotide metabolic process GO:0006163 302 0.174
regulation of ras gtpase activity GO:0032318 88 0.173
positive regulation of hydrolase activity GO:0051345 148 0.172
regulation of autophagic vacuole assembly GO:2000785 4 0.171
regulation of nucleotide metabolic process GO:0006140 169 0.171
neuron projection guidance GO:0097485 141 0.171
negative regulation of protein metabolic process GO:0051248 282 0.170
axon guidance GO:0007411 141 0.170
regulation of hydrolase activity GO:0051336 246 0.169
amine metabolic process GO:0009308 45 0.169
syncytium formation by plasma membrane fusion GO:0000768 42 0.167
Mouse
embryonic skeletal system development GO:0048706 120 0.167
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.165
single organismal cell cell adhesion GO:0016337 131 0.162
guanosine containing compound catabolic process GO:1901069 144 0.160
glycosyl compound catabolic process GO:1901658 206 0.160
response to nutrient levels GO:0031667 109 0.159
Rat
regulation of lipid metabolic process GO:0019216 118 0.158
Mouse Rat
rho protein signal transduction GO:0007266 32 0.158
mitotic nuclear division GO:0007067 48 0.155
Human
positive regulation of cellular catabolic process GO:0031331 148 0.153
positive regulation of gtpase activity GO:0043547 85 0.151
nucleotide catabolic process GO:0009166 217 0.151
carbohydrate derivative catabolic process GO:1901136 231 0.151
positive regulation of cell growth GO:0030307 33 0.151
peptidyl amino acid modification GO:0018193 336 0.148
nucleoside triphosphate metabolic process GO:0009141 230 0.148
skeletal muscle fiber development GO:0048741 58 0.147
mitotic cell cycle process GO:1903047 159 0.146
Human
calcium ion homeostasis GO:0055074 127 0.144
purine nucleoside catabolic process GO:0006152 205 0.143
axonogenesis GO:0007409 274 0.142
protein kinase c signaling GO:0070528 7 0.141
regulation of glycogen biosynthetic process GO:0005979 7 0.141
gonad development GO:0008406 141 0.140
regulation of protein kinase activity GO:0045859 232 0.140
neural tube formation GO:0001841 108 0.139
developmental maturation GO:0021700 193 0.138
eye photoreceptor cell differentiation GO:0001754 41 0.138
locomotory behavior GO:0007626 195 0.138
regulation of jnk cascade GO:0046328 62 0.137
regulation of purine nucleotide catabolic process GO:0033121 122 0.136
purine containing compound catabolic process GO:0072523 213 0.136
endochondral bone morphogenesis GO:0060350 50 0.136
negative regulation of mapk cascade GO:0043409 65 0.135
Mouse
protein kinase b signaling GO:0043491 74 0.135
Human Mouse
protein autophosphorylation GO:0046777 61 0.135
regulation of reactive oxygen species metabolic process GO:2000377 40 0.134
prostate gland morphogenesis GO:0060512 32 0.133
Mouse
organonitrogen compound catabolic process GO:1901565 264 0.133
vacuole organization GO:0007033 38 0.133
cation homeostasis GO:0055080 212 0.132
guanosine containing compound metabolic process GO:1901068 144 0.131
regulation of insulin receptor signaling pathway GO:0046626 21 0.131
ribonucleoside metabolic process GO:0009119 245 0.131
cytoplasmic transport GO:0016482 234 0.131
ossification GO:0001503 216 0.131
skeletal muscle organ development GO:0060538 163 0.131
cellular ion homeostasis GO:0006873 165 0.131
response to transforming growth factor beta GO:0071559 88 0.130
regulation of nuclear division GO:0051783 56 0.130
Human
generation of precursor metabolites and energy GO:0006091 103 0.129
negative regulation of feeding behavior GO:2000252 1 0.129
regulation of cell cycle process GO:0010564 160 0.128
Human
syncytium formation GO:0006949 43 0.128
Mouse
regulation of proteolysis GO:0030162 164 0.127
regulation of system process GO:0044057 200 0.127
muscle tissue development GO:0060537 308 0.126
retina morphogenesis in camera type eye GO:0060042 45 0.126
positive regulation of cell cycle GO:0045787 92 0.125
Human
epithelial cell proliferation GO:0050673 174 0.125
organelle assembly GO:0070925 177 0.124
regulation of gtp catabolic process GO:0033124 113 0.124
stem cell differentiation GO:0048863 268 0.122
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.122
cellular carbohydrate metabolic process GO:0044262 119 0.121
peptidyl tyrosine modification GO:0018212 145 0.119
glycosyl compound metabolic process GO:1901657 246 0.119
ribonucleoside catabolic process GO:0042454 206 0.118
positive regulation of camp mediated signaling GO:0043950 3 0.117
cellular glucan metabolic process GO:0006073 32 0.116
inner ear morphogenesis GO:0042472 101 0.116
stress activated protein kinase signaling cascade GO:0031098 81 0.115
glucose transport GO:0015758 56 0.115
purine ribonucleoside metabolic process GO:0046128 241 0.114
ribonucleoside triphosphate catabolic process GO:0009203 199 0.114
positive regulation of mapk cascade GO:0043410 170 0.113
Human Mouse
protein localization to nucleus GO:0034504 121 0.112
regulation of cysteine type endopeptidase activity GO:2000116 65 0.111
digestive tract development GO:0048565 190 0.111
positive regulation of nucleotide metabolic process GO:0045981 114 0.111
regulation of protein kinase b signaling GO:0051896 56 0.111
Human Mouse
multicellular organismal reproductive behavior GO:0033057 23 0.109
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.109
cellular nitrogen compound catabolic process GO:0044270 280 0.109
circulatory system process GO:0003013 197 0.107
muscle fiber development GO:0048747 76 0.107
purine nucleoside triphosphate catabolic process GO:0009146 203 0.106
insulin receptor signaling pathway GO:0008286 49 0.106
carbohydrate metabolic process GO:0005975 230 0.105
embryonic skeletal system morphogenesis GO:0048704 91 0.105
myeloid leukocyte differentiation GO:0002573 119 0.105
regulation of establishment of protein localization GO:0070201 181 0.104
nucleoside metabolic process GO:0009116 246 0.104
regulation of carbohydrate metabolic process GO:0006109 75 0.104
organophosphate catabolic process GO:0046434 232 0.103
organic cyclic compound catabolic process GO:1901361 295 0.102
regulation of anatomical structure size GO:0090066 178 0.102
regulation of leukocyte differentiation GO:1902105 159 0.102
autophagic vacuole assembly GO:0000045 13 0.100
ion transmembrane transport GO:0034220 361 0.099
nucleoside catabolic process GO:0009164 206 0.098
morphogenesis of a branching epithelium GO:0061138 193 0.098
Mouse
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.097
cell maturation GO:0048469 127 0.095
stem cell development GO:0048864 219 0.094
neural crest cell differentiation GO:0014033 54 0.093
embryonic placenta development GO:0001892 98 0.093
regulation of mitotic cell cycle GO:0007346 126 0.092
Human
g protein coupled receptor signaling pathway GO:0007186 243 0.092
blood circulation GO:0008015 195 0.091
regulation of generation of precursor metabolites and energy GO:0043467 38 0.091
regulation of protein catabolic process GO:0042176 108 0.091
skeletal system morphogenesis GO:0048705 203 0.090
regulation of cell projection organization GO:0031344 206 0.090
regulation of body fluid levels GO:0050878 162 0.090
regulation of glucose metabolic process GO:0010906 60 0.090
dorsal ventral axon guidance GO:0033563 3 0.090
digestive system development GO:0055123 200 0.089
heart process GO:0003015 94 0.089
regulation of steroid biosynthetic process GO:0050810 26 0.089
Rat
regulation of osteoblast differentiation GO:0045667 67 0.088
regulation of vacuole organization GO:0044088 4 0.088
cell type specific apoptotic process GO:0097285 268 0.088
cellular homeostasis GO:0019725 240 0.087
regulation of purine nucleotide metabolic process GO:1900542 169 0.087
regulation of ras protein signal transduction GO:0046578 114 0.087
ribonucleoside triphosphate metabolic process GO:0009199 220 0.086
purine ribonucleoside catabolic process GO:0046130 205 0.086
regulation of secretion GO:0051046 274 0.085
t cell differentiation in thymus GO:0033077 77 0.085
feeding behavior GO:0007631 62 0.085
regulation of endopeptidase activity GO:0052548 89 0.084
visual perception GO:0007601 52 0.083
inorganic cation transmembrane transport GO:0098662 207 0.083
hexose metabolic process GO:0019318 98 0.082
aromatic compound catabolic process GO:0019439 286 0.082
cellular polysaccharide metabolic process GO:0044264 38 0.082
osteoclast differentiation GO:0030316 62 0.082
dna metabolic process GO:0006259 303 0.081
negative regulation of cellular catabolic process GO:0031330 47 0.081
ureteric bud development GO:0001657 94 0.081
response to peptide GO:1901652 136 0.081
cellular divalent inorganic cation homeostasis GO:0072503 127 0.081
neural retina development GO:0003407 41 0.081
regulation of cellular amino acid metabolic process GO:0006521 5 0.080
transmembrane transport GO:0055085 412 0.080
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.080
learning or memory GO:0007611 148 0.080
Rat
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.080
aortic valve morphogenesis GO:0003180 4 0.079
central nervous system neuron development GO:0021954 67 0.079
regulation of cytoplasmic transport GO:1903649 112 0.079
activation of adenylate cyclase activity GO:0007190 4 0.079
mesenchymal cell differentiation GO:0048762 107 0.077
monosaccharide metabolic process GO:0005996 106 0.077
regulation of mapk cascade GO:0043408 248 0.077
Human Mouse
negative regulation of ossification GO:0030279 49 0.076
rac protein signal transduction GO:0016601 13 0.076
melanocyte differentiation GO:0030318 25 0.076
cellular response to nutrient levels GO:0031669 64 0.076
anatomical structure homeostasis GO:0060249 145 0.075
spinal cord development GO:0021510 81 0.074
regulation of organelle organization GO:0033043 289 0.074
Human Mouse
glucose import GO:0046323 32 0.074
energy derivation by oxidation of organic compounds GO:0015980 77 0.074
regulation of muscle cell apoptotic process GO:0010660 17 0.073
reactive oxygen species metabolic process GO:0072593 84 0.073
morphogenesis of a branching structure GO:0001763 203 0.072
Mouse
mitral valve development GO:0003174 4 0.072
male germ line stem cell asymmetric division GO:0048133 2 0.071
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.071
purine containing compound metabolic process GO:0072521 311 0.071
positive regulation of nucleotide catabolic process GO:0030813 88 0.071
ribose phosphate metabolic process GO:0019693 291 0.071
embryonic appendage morphogenesis GO:0035113 126 0.070
muscle adaptation GO:0043500 39 0.070
regulation of protein serine threonine kinase activity GO:0071900 157 0.069
regulation of protein processing GO:0070613 96 0.069
cytosolic calcium ion homeostasis GO:0051480 70 0.069
regulation of myeloid cell differentiation GO:0045637 96 0.069
macromolecule methylation GO:0043414 120 0.069
regulation of protein maturation GO:1903317 96 0.068
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.068
regulation of leukocyte proliferation GO:0070663 121 0.068
Human
regulation of response to wounding GO:1903034 189 0.068
asymmetric stem cell division GO:0098722 3 0.068
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.068
myotube cell development GO:0014904 60 0.067
negative regulation of cell cycle process GO:0010948 69 0.066
forebrain generation of neurons GO:0021872 63 0.066
hormone biosynthetic process GO:0042446 16 0.066
Rat
regulation of steroid hormone biosynthetic process GO:0090030 4 0.066
Rat
endocrine system development GO:0035270 98 0.065
forebrain development GO:0030900 302 0.064
Zebrafish
positive regulation of striated muscle tissue development GO:0045844 31 0.064
hormone metabolic process GO:0042445 86 0.063
Rat
leukocyte proliferation GO:0070661 172 0.063
Human
positive regulation of hormone metabolic process GO:0032352 3 0.063
Rat
regulation of canonical wnt signaling pathway GO:0060828 82 0.062
regulation of developmental pigmentation GO:0048070 14 0.062
regulation of phosphate transport GO:0010966 1 0.061
embryonic limb morphogenesis GO:0030326 126 0.061
monosaccharide transport GO:0015749 58 0.061
nuclear division GO:0000280 158 0.061
Human
positive regulation of gtp catabolic process GO:0033126 85 0.060
positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 12 0.060
cellular response to hormone stimulus GO:0032870 150 0.060
sensory perception GO:0007600 245 0.060
negative regulation of hydrolase activity GO:0051346 71 0.059
nephron tubule morphogenesis GO:0072078 68 0.059
inorganic ion transmembrane transport GO:0098660 234 0.059
action potential GO:0001508 78 0.059
adult walking behavior GO:0007628 41 0.058
negative regulation of cellular amine metabolic process GO:0033239 1 0.058
cellular protein catabolic process GO:0044257 155 0.058
cellular calcium ion homeostasis GO:0006874 119 0.058
multi multicellular organism process GO:0044706 109 0.057
Rat
detection of abiotic stimulus GO:0009582 60 0.057
ear morphogenesis GO:0042471 118 0.057
regulation of ossification GO:0030278 112 0.057
biomineral tissue development GO:0031214 64 0.057
blood vessel morphogenesis GO:0048514 285 0.056
modification dependent protein catabolic process GO:0019941 133 0.055
regulation of cell activation GO:0050865 289 0.055
Human
endocytosis GO:0006897 168 0.054
protein maturation GO:0051604 176 0.054
primary neural tube formation GO:0014020 95 0.054
forebrain neuron differentiation GO:0021879 52 0.054
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.054
ribonucleotide catabolic process GO:0009261 208 0.054
methylation GO:0032259 134 0.053
g protein coupled acetylcholine receptor signaling pathway GO:0007213 4 0.053
response to alkaline ph GO:0010446 1 0.053
polysaccharide biosynthetic process GO:0000271 20 0.053
positive regulation of ras gtpase activity GO:0032320 65 0.053
cell fate commitment GO:0045165 210 0.053
cellular ketone metabolic process GO:0042180 84 0.052
nucleobase containing small molecule metabolic process GO:0055086 352 0.052
regulation of camp mediated signaling GO:0043949 7 0.052
negative regulation of protein phosphorylation GO:0001933 126 0.051
negative regulation of protein modification process GO:0031400 163 0.051
glycoprotein metabolic process GO:0009100 116 0.051
Mouse
cellular response to external stimulus GO:0071496 88 0.051
Rat
jnk cascade GO:0007254 72 0.051
mesonephric duct morphogenesis GO:0072180 4 0.050
positive regulation of muscle tissue development GO:1901863 32 0.050
response to purine containing compound GO:0014074 28 0.050
regulation of glucose transport GO:0010827 32 0.050
regulation of blood pressure GO:0008217 93 0.050
embryonic camera type eye development GO:0031076 36 0.050
regulation of cellular component biogenesis GO:0044087 181 0.050
regulation of heart rate GO:0002027 36 0.049
cellular response to abiotic stimulus GO:0071214 56 0.049
Rat
appendage development GO:0048736 166 0.049
positive regulation of growth GO:0045927 104 0.049
protein processing GO:0016485 163 0.049
embryonic epithelial tube formation GO:0001838 130 0.048
glucan biosynthetic process GO:0009250 14 0.048
skeletal system development GO:0001501 356 0.048
cardiac cell fate specification GO:0060912 2 0.048
glycogen metabolic process GO:0005977 32 0.048
heart trabecula formation GO:0060347 14 0.048
carbohydrate transport GO:0008643 62 0.047
cardiac chamber development GO:0003205 108 0.047
regulation of cell division GO:0051302 76 0.047
Human
mating GO:0007618 27 0.047
regulation of peptidase activity GO:0052547 96 0.047
skin development GO:0043588 220 0.046
positive regulation of protein phosphorylation GO:0001934 242 0.046
hindlimb morphogenesis GO:0035137 42 0.046
motor neuron axon guidance GO:0008045 26 0.046
photoreceptor cell differentiation GO:0046530 52 0.046
cell substrate adhesion GO:0031589 130 0.046
response to parathyroid hormone GO:0071107 3 0.046
embryonic hindlimb morphogenesis GO:0035116 32 0.045
multicellular organismal signaling GO:0035637 91 0.045
epithelial to mesenchymal transition GO:0001837 47 0.045
meiotic nuclear division GO:0007126 115 0.045
regulation of eosinophil migration GO:2000416 2 0.045
response to light stimulus GO:0009416 135 0.045
camera type eye photoreceptor cell differentiation GO:0060219 15 0.045
lipid biosynthetic process GO:0008610 179 0.045
Rat
positive regulation of ossification GO:0045778 47 0.045
carbohydrate derivative biosynthetic process GO:1901137 183 0.045
Mouse
phosphate ion transport GO:0006817 3 0.044
skeletal muscle cell differentiation GO:0035914 66 0.044
regulation of wnt signaling pathway GO:0030111 123 0.044
male sex determination GO:0030238 14 0.044
synapse organization GO:0050808 125 0.043
multi organism behavior GO:0051705 62 0.043
positive regulation of cell migration GO:0030335 109 0.043
regulation of cell adhesion GO:0030155 154 0.043
cardiac chamber morphogenesis GO:0003206 93 0.043
regulation of hormone metabolic process GO:0032350 15 0.043
Rat
regulation of intracellular protein transport GO:0033157 82 0.042
regulation of proteasomal protein catabolic process GO:0061136 46 0.042
negative regulation of insulin receptor signaling pathway GO:0046627 14 0.042
negative regulation of immune system process GO:0002683 209 0.042
ribonucleotide metabolic process GO:0009259 291 0.042
negative regulation of glycogen metabolic process GO:0070874 2 0.042
carbohydrate biosynthetic process GO:0016051 74 0.042
exocrine system development GO:0035272 45 0.042
molting cycle GO:0042303 90 0.041
positive regulation of epithelial cell proliferation GO:0050679 68 0.041
neuromuscular process GO:0050905 99 0.041
positive regulation of protein kinase activity GO:0045860 144 0.041
epithelial cell development GO:0002064 159 0.041
negative regulation of nervous system development GO:0051961 156 0.041
cellular response to dna damage stimulus GO:0006974 207 0.041
positive regulation of programmed cell death GO:0043068 218 0.041
response to peptide hormone GO:0043434 127 0.040
positive regulation of camp metabolic process GO:0030816 19 0.040
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.040
cardiac ventricle morphogenesis GO:0003208 50 0.040
regulation of nucleocytoplasmic transport GO:0046822 73 0.040
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.040
tube formation GO:0035148 140 0.040
immune effector process GO:0002252 321 0.040
neuron remodeling GO:0016322 7 0.040
detection of stimulus GO:0051606 84 0.039
regulation of cell size GO:0008361 72 0.039
negative regulation of dendritic spine morphogenesis GO:0061002 3 0.039
regulation of cellular component size GO:0032535 121 0.039
endomembrane system organization GO:0010256 147 0.039
positive regulation of glucose metabolic process GO:0010907 21 0.038
negative regulation of protein processing GO:0010955 79 0.038
actin cytoskeleton organization GO:0030036 220 0.038
regulation of myeloid leukocyte differentiation GO:0002761 58 0.038
cerebral cortex development GO:0021987 86 0.038
protein import GO:0017038 101 0.038
positive regulation of heart growth GO:0060421 18 0.038
peptidyl tyrosine autophosphorylation GO:0038083 5 0.038
apoptotic signaling pathway GO:0097190 306 0.038
Mouse
regulation of protein localization GO:0032880 231 0.038
neural crest cell development GO:0014032 48 0.037
nitrogen compound transport GO:0071705 271 0.037
lamellipodium organization GO:0097581 29 0.037
female mating behavior GO:0060180 8 0.037
cation transport GO:0006812 399 0.037
response to molecule of bacterial origin GO:0002237 143 0.037
regulation of epithelial cell proliferation GO:0050678 141 0.036
t cell activation GO:0042110 289 0.036
Human
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 43 0.036
uterus development GO:0060065 16 0.036
regulation of stress activated mapk cascade GO:0032872 69 0.036
regulation of protein targeting GO:1903533 61 0.036
response to organic cyclic compound GO:0014070 198 0.036
Rat
fibroblast growth factor receptor signaling pathway GO:0008543 46 0.036
positive regulation of nucleoside metabolic process GO:0045979 91 0.036
fibroblast migration GO:0010761 21 0.036
negative regulation of synapse assembly GO:0051964 3 0.035
maintenance of location GO:0051235 89 0.035
regulation of calcium ion transport GO:0051924 69 0.035
regulation of protein localization to nucleus GO:1900180 60 0.035
homotypic cell cell adhesion GO:0034109 28 0.035
sensory perception of light stimulus GO:0050953 54 0.035
embryonic digit morphogenesis GO:0042733 56 0.035
wound healing GO:0042060 157 0.035
Zebrafish Rat
cell division GO:0051301 120 0.035
Human
vascular endothelial growth factor receptor signaling pathway GO:0048010 24 0.035
myosin filament organization GO:0031033 3 0.034
positive regulation of epidermal growth factor activated receptor activity GO:0045741 2 0.034
norepinephrine transport GO:0015874 2 0.034
establishment or maintenance of cell polarity GO:0007163 86 0.034
Mouse
leukocyte activation involved in immune response GO:0002366 126 0.034
morphogenesis of embryonic epithelium GO:0016331 159 0.034
rhombomere formation GO:0021594 1 0.034
germ line stem cell division GO:0042078 2 0.034
positive regulation of behavior GO:0048520 40 0.034
polysaccharide metabolic process GO:0005976 39 0.033
nucleoside phosphate catabolic process GO:1901292 222 0.033
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.033
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.033
forebrain neuron development GO:0021884 30 0.033
axon target recognition GO:0007412 4 0.033

Igf2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.682
cancer DOID:162 0 0.179
organ system cancer DOID:0050686 0 0.179
gastrointestinal system cancer DOID:3119 0 0.128
disease of metabolism DOID:0014667 0 0.078
inherited metabolic disorder DOID:655 0 0.078