Mus musculus

110 known processes

Dync2h1

dynein cytoplasmic 2 heavy chain 1

(Aliases: 4432416O06Rik,D330044F14Rik,AI448217,D030010H02Rik,mKIAA1997,DHC1b,Dnchc2,DHC2)

Dync2h1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cilium assembly GO:0042384 81 0.873
regulation of cilium assembly GO:1902017 7 0.804
cilium morphogenesis GO:0060271 102 0.785
cellular component assembly involved in morphogenesis GO:0010927 139 0.398
organelle assembly GO:0070925 177 0.194
intraciliary retrograde transport GO:0035721 3 0.141
smoothened signaling pathway GO:0007224 105 0.098
establishment of planar polarity GO:0001736 28 0.067
nonmotile primary cilium assembly GO:0035058 8 0.066
epithelial tube formation GO:0072175 130 0.057
regulation of smoothened signaling pathway GO:0008589 58 0.056
regulation of organelle organization GO:0033043 289 0.053
establishment of tissue polarity GO:0007164 28 0.049
positive regulation of cell projection organization GO:0031346 95 0.049
intraciliary transport GO:0042073 9 0.046
embryonic epithelial tube formation GO:0001838 130 0.046
microtubule based process GO:0007017 236 0.045
spinal cord development GO:0021510 81 0.043
skeletal system development GO:0001501 356 0.042
regulation of cell projection organization GO:0031344 206 0.041
primary neural tube formation GO:0014020 95 0.040
regionalization GO:0003002 337 0.037
neural tube development GO:0021915 160 0.037
wnt signaling pathway GO:0016055 188 0.037
cellular amino acid metabolic process GO:0006520 103 0.035
negative regulation of cell proliferation GO:0008285 296 0.035
transmembrane transport GO:0055085 412 0.034
microtubule based movement GO:0007018 84 0.033
epithelial tube morphogenesis GO:0060562 303 0.033
regulation of cellular ketone metabolic process GO:0010565 66 0.033
regulation of cell projection assembly GO:0060491 38 0.031
regulation of cellular amine metabolic process GO:0033238 20 0.030
regulation of cellular component biogenesis GO:0044087 181 0.030
morphogenesis of embryonic epithelium GO:0016331 159 0.029
negative regulation of cellular component organization GO:0051129 194 0.029
tube formation GO:0035148 140 0.029
cellular amine metabolic process GO:0044106 44 0.028
limb morphogenesis GO:0035108 149 0.028
skin development GO:0043588 220 0.027
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.027
Worm
amine metabolic process GO:0009308 45 0.027
tube closure GO:0060606 91 0.027
response to growth factor GO:0070848 198 0.027
Worm
embryonic organ morphogenesis GO:0048562 276 0.027
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.026
neural tube formation GO:0001841 108 0.026
positive regulation of organelle organization GO:0010638 128 0.026
positive regulation of cellular amine metabolic process GO:0033240 5 0.026
cellular ketone metabolic process GO:0042180 84 0.026
regulation of cellular amino acid metabolic process GO:0006521 5 0.025
apoptotic signaling pathway GO:0097190 306 0.025
cellular nitrogen compound catabolic process GO:0044270 280 0.025
cellular response to growth factor stimulus GO:0071363 197 0.024
Worm
organic cyclic compound catabolic process GO:1901361 295 0.024
regulation of wnt signaling pathway GO:0030111 123 0.024
spermatogenesis GO:0007283 284 0.023
negative regulation of protein metabolic process GO:0051248 282 0.023
regulation of organelle assembly GO:1902115 19 0.023
small gtpase mediated signal transduction GO:0007264 97 0.022
purine nucleotide metabolic process GO:0006163 302 0.022
response to organonitrogen compound GO:0010243 246 0.022
macromolecule catabolic process GO:0009057 281 0.022
morphogenesis of a polarized epithelium GO:0001738 37 0.022
heterocycle catabolic process GO:0046700 280 0.022
organonitrogen compound catabolic process GO:1901565 264 0.022
positive regulation of cellular component biogenesis GO:0044089 94 0.021
nucleobase containing small molecule metabolic process GO:0055086 352 0.021
membrane organization GO:0061024 245 0.021
negative regulation of cellular protein metabolic process GO:0032269 247 0.021
ras protein signal transduction GO:0007265 77 0.021
rho protein signal transduction GO:0007266 32 0.020
skeletal system morphogenesis GO:0048705 203 0.020
ribonucleotide metabolic process GO:0009259 291 0.020
aromatic compound catabolic process GO:0019439 286 0.020
ion transmembrane transport GO:0034220 361 0.020
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.020
nucleoside phosphate metabolic process GO:0006753 338 0.020
microtubule cytoskeleton organization GO:0000226 157 0.019
purine nucleotide catabolic process GO:0006195 211 0.019
nucleotide metabolic process GO:0009117 332 0.019
spermatid differentiation GO:0048515 115 0.019
posttranscriptional regulation of gene expression GO:0010608 155 0.019
positive regulation of hydrolase activity GO:0051345 148 0.019
cation transport GO:0006812 399 0.019
purine containing compound metabolic process GO:0072521 311 0.019
telencephalon development GO:0021537 186 0.019
methylation GO:0032259 134 0.018
protein maturation GO:0051604 176 0.018
neural tube closure GO:0001843 90 0.018
endocytosis GO:0006897 168 0.018
nucleoside metabolic process GO:0009116 246 0.018
cellular response to organonitrogen compound GO:0071417 145 0.018
negative regulation of wnt signaling pathway GO:0030178 73 0.018
regulation of cellular response to growth factor stimulus GO:0090287 82 0.018
Worm
nucleoside phosphate catabolic process GO:1901292 222 0.018
cellular homeostasis GO:0019725 240 0.018
regulation of secretion GO:0051046 274 0.018
ribonucleoside triphosphate metabolic process GO:0009199 220 0.018
nucleoside catabolic process GO:0009164 206 0.017
purine nucleoside triphosphate metabolic process GO:0009144 226 0.017
purine nucleoside triphosphate catabolic process GO:0009146 203 0.017
regulation of membrane potential GO:0042391 192 0.017
mitotic cell cycle GO:0000278 195 0.017
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.017
cytoplasmic transport GO:0016482 234 0.017
fat cell differentiation GO:0045444 160 0.016
protein processing GO:0016485 163 0.016
nucleotide catabolic process GO:0009166 217 0.016
spermatid development GO:0007286 108 0.016
ribose phosphate metabolic process GO:0019693 291 0.016
purine nucleoside metabolic process GO:0042278 241 0.016
glycosyl compound catabolic process GO:1901658 206 0.016
protein localization to organelle GO:0033365 185 0.016
carbohydrate metabolic process GO:0005975 230 0.016
regulation of hydrolase activity GO:0051336 246 0.016
germ cell development GO:0007281 185 0.016
protein catabolic process GO:0030163 221 0.016
glycosyl compound metabolic process GO:1901657 246 0.016
organic anion transport GO:0015711 137 0.016
spinal cord dorsal ventral patterning GO:0021513 23 0.016
protein localization to membrane GO:0072657 108 0.016
regulation of secretion by cell GO:1903530 249 0.016
dna metabolic process GO:0006259 303 0.016
regulation of cell activation GO:0050865 289 0.015
establishment or maintenance of cell polarity GO:0007163 86 0.015
male gamete generation GO:0048232 285 0.015
peptidyl amino acid modification GO:0018193 336 0.015
exocytosis GO:0006887 121 0.015
carboxylic acid transport GO:0046942 100 0.015
urogenital system development GO:0001655 261 0.015
protein modification by small protein conjugation or removal GO:0070647 207 0.015
purine nucleoside catabolic process GO:0006152 205 0.015
reactive oxygen species metabolic process GO:0072593 84 0.015
carboxylic acid biosynthetic process GO:0046394 86 0.015
spinal cord patterning GO:0021511 25 0.015
nucleoside triphosphate metabolic process GO:0009141 230 0.015
cilium movement GO:0003341 28 0.015
organophosphate catabolic process GO:0046434 232 0.015
regulation of hormone levels GO:0010817 211 0.015
multicellular organismal homeostasis GO:0048871 164 0.015
positive regulation of protein modification process GO:0031401 299 0.015
regulation of cell cycle GO:0051726 281 0.015
organic acid biosynthetic process GO:0016053 86 0.015
respiratory system development GO:0060541 190 0.015
cellular lipid metabolic process GO:0044255 323 0.015
embryonic limb morphogenesis GO:0030326 126 0.015
limb development GO:0060173 166 0.014
canonical wnt signaling pathway GO:0060070 130 0.014
regulation of lymphocyte activation GO:0051249 240 0.014
anatomical structure homeostasis GO:0060249 145 0.014
metal ion homeostasis GO:0055065 189 0.014
purine ribonucleotide catabolic process GO:0009154 208 0.014
embryonic skeletal system development GO:0048706 120 0.014
actin cytoskeleton organization GO:0030036 220 0.014
positive regulation of cellular catabolic process GO:0031331 148 0.014
regulation of embryonic development GO:0045995 71 0.014
cellular response to dna damage stimulus GO:0006974 207 0.014
synaptic transmission GO:0007268 329 0.014
sensory perception GO:0007600 245 0.014
Fly
cellular macromolecule catabolic process GO:0044265 206 0.014
ribonucleoside metabolic process GO:0009119 245 0.014
ribonucleotide catabolic process GO:0009261 208 0.014
divalent inorganic cation transport GO:0072511 178 0.014
modification dependent macromolecule catabolic process GO:0043632 133 0.014
fertilization GO:0009566 127 0.014
anion transport GO:0006820 177 0.014
g protein coupled receptor signaling pathway GO:0007186 243 0.014
cell adhesion GO:0007155 329 0.014
regulation of cell adhesion GO:0030155 154 0.014
nitrogen compound transport GO:0071705 271 0.013
regulation of nucleotide metabolic process GO:0006140 169 0.013
intracellular protein transport GO:0006886 204 0.013
forebrain development GO:0030900 302 0.013
organelle fission GO:0048285 170 0.013
purine ribonucleoside metabolic process GO:0046128 241 0.013
carbohydrate homeostasis GO:0033500 128 0.013
ribonucleoside triphosphate catabolic process GO:0009203 199 0.013
carbohydrate derivative catabolic process GO:1901136 231 0.013
ribonucleoside catabolic process GO:0042454 206 0.013
organelle localization GO:0051640 179 0.013
organic hydroxy compound metabolic process GO:1901615 203 0.013
appendage development GO:0048736 166 0.013
peptide hormone secretion GO:0030072 109 0.013
purine containing compound catabolic process GO:0072523 213 0.013
cation transmembrane transport GO:0098655 266 0.013
cell type specific apoptotic process GO:0097285 268 0.013
embryonic appendage morphogenesis GO:0035113 126 0.013
inorganic cation transmembrane transport GO:0098662 207 0.013
purine ribonucleotide metabolic process GO:0009150 290 0.013
regulation of cell migration GO:0030334 219 0.013
regulation of vacuole organization GO:0044088 4 0.012
cell maturation GO:0048469 127 0.012
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.012
cellularization GO:0007349 1 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.012
purine ribonucleoside catabolic process GO:0046130 205 0.012
cellular chemical homeostasis GO:0055082 215 0.012
macromolecule methylation GO:0043414 120 0.012
homeostasis of number of cells GO:0048872 210 0.012
nucleoside triphosphate catabolic process GO:0009143 205 0.012
regulation of transferase activity GO:0051338 263 0.012
small molecule biosynthetic process GO:0044283 132 0.012
peptide transport GO:0015833 133 0.012
cellular response to hormone stimulus GO:0032870 150 0.012
negative regulation of intracellular signal transduction GO:1902532 167 0.012
regulation of neuron differentiation GO:0045664 281 0.012
regulation of protein processing GO:0070613 96 0.012
inorganic ion transmembrane transport GO:0098660 234 0.012
stem cell differentiation GO:0048863 268 0.012
response to insulin GO:0032868 100 0.012
heart morphogenesis GO:0003007 178 0.012
leukocyte differentiation GO:0002521 342 0.012
organic acid transport GO:0015849 101 0.012
lymphocyte differentiation GO:0030098 242 0.012
regulation of vesicle mediated transport GO:0060627 139 0.012
activation of meiosis involved in egg activation GO:0060466 2 0.012
regulation of apoptotic signaling pathway GO:2001233 197 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.012
negative regulation of cell morphogenesis involved in differentiation GO:0010771 48 0.012
protein targeting GO:0006605 143 0.012
response to radiation GO:0009314 165 0.012
amide transport GO:0042886 138 0.012
tissue homeostasis GO:0001894 115 0.012
purine nucleoside monophosphate metabolic process GO:0009126 81 0.012
regulation of cellular catabolic process GO:0031329 242 0.012
cytoskeleton dependent intracellular transport GO:0030705 50 0.012
transmission of nerve impulse GO:0019226 76 0.012
retrograde transport endosome to golgi GO:0042147 2 0.011
divalent inorganic cation homeostasis GO:0072507 138 0.011
regulation of protein localization GO:0032880 231 0.011
lateral inhibition GO:0046331 1 0.011
mitotic cell cycle process GO:1903047 159 0.011
positive regulation of nucleotide metabolic process GO:0045981 114 0.011
guanosine containing compound catabolic process GO:1901069 144 0.011
cytokine production GO:0001816 319 0.011
epidermis development GO:0008544 187 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.011
cation homeostasis GO:0055080 212 0.011
myosin filament assembly GO:0031034 2 0.011
photoreceptor cell maintenance GO:0045494 19 0.011
neuron death GO:0070997 154 0.011
regulation of cell motility GO:2000145 236 0.011
regulation of establishment of protein localization GO:0070201 181 0.011
developmental maturation GO:0021700 193 0.011
nuclear division GO:0000280 158 0.011
regulation of kinase activity GO:0043549 249 0.011
regulation of cell cycle process GO:0010564 160 0.011
negative regulation of organelle organization GO:0010639 90 0.011
covalent chromatin modification GO:0016569 163 0.011
negative regulation of phosphorylation GO:0042326 166 0.011
b cell activation GO:0042113 161 0.011
compound eye development GO:0048749 1 0.011
oocyte axis specification GO:0007309 2 0.011
reactive nitrogen species metabolic process GO:2001057 0 0.011
lung development GO:0030324 164 0.011
muscle tissue development GO:0060537 308 0.011
positive regulation of gtpase activity GO:0043547 85 0.011
reactive oxygen species biosynthetic process GO:1903409 8 0.010
regulation of protein kinase activity GO:0045859 232 0.010
regulation of homeostatic process GO:0032844 182 0.010
cellular response to peptide hormone stimulus GO:0071375 92 0.010
positive regulation of cell development GO:0010720 237 0.010
fibroblast growth factor receptor signaling pathway GO:0008543 46 0.010
response to organic cyclic compound GO:0014070 198 0.010
cellular protein complex assembly GO:0043623 116 0.010
cellular response to fibroblast growth factor stimulus GO:0044344 47 0.010
positive regulation of programmed cell death GO:0043068 218 0.010
regulation of ion transmembrane transport GO:0034765 119 0.010
response to light stimulus GO:0009416 135 0.010

Dync2h1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.027
nervous system disease DOID:863 0 0.027
cancer DOID:162 0 0.026
organ system cancer DOID:0050686 0 0.026
disease of cellular proliferation DOID:14566 0 0.026
immune system disease DOID:2914 0 0.017
musculoskeletal system disease DOID:17 0 0.016
hematopoietic system disease DOID:74 0 0.014
central nervous system disease DOID:331 0 0.012
connective tissue disease DOID:65 0 0.011
congenital hypoplastic anemia DOID:1342 0 0.010
anemia DOID:2355 0 0.010
bone marrow disease DOID:4961 0 0.010
aplastic anemia DOID:12449 0 0.010
bone disease DOID:0080001 0 0.010