|
|
muscle system process
|
GO:0003012 |
141 |
0.950
|
|
|
|
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway
|
GO:0051482 |
4 |
0.924
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.777
|
|
|
|
muscle contraction
|
GO:0006936 |
101 |
0.716
|
|
|
|
regulation of muscle contraction
|
GO:0006937 |
49 |
0.710
|
|
|
|
smooth muscle contraction
|
GO:0006939 |
44 |
0.701
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.670
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.599
|
|
|
|
regulation of muscle system process
|
GO:0090257 |
80 |
0.524
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.521
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.469
|
Human Mouse Worm Fly |
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.405
|
Human Mouse |
|
|
circulatory system process
|
GO:0003013 |
197 |
0.397
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
70 |
0.397
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.385
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.346
|
|
|
|
regulation of smooth muscle contraction
|
GO:0006940 |
22 |
0.324
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.314
|
Mouse Worm Fly |
|
|
angiogenesis
|
GO:0001525 |
201 |
0.298
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
84 |
0.278
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.272
|
Human Mouse |
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.248
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.247
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.239
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.239
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.237
|
Mouse |
|
|
cell junction organization
|
GO:0034330 |
77 |
0.235
|
|
|
|
actin filament organization
|
GO:0007015 |
113 |
0.235
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.232
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.227
|
|
|
|
cardiac muscle cell development
|
GO:0055013 |
39 |
0.225
|
Human Mouse |
|
|
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger
|
GO:0007187 |
55 |
0.208
|
|
|
|
organelle assembly
|
GO:0070925 |
177 |
0.207
|
Mouse Worm Fly |
|
|
lung development
|
GO:0030324 |
164 |
0.193
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
266 |
0.192
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.185
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.168
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.167
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
234 |
0.157
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
88 |
0.147
|
|
|
|
actin filament based movement
|
GO:0030048 |
23 |
0.145
|
Mouse |
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.139
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.137
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.137
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
159 |
0.133
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.133
|
Fly |
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.130
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.130
|
|
|
|
adenylate cyclase modulating g protein coupled receptor signaling pathway
|
GO:0007188 |
54 |
0.123
|
|
|
|
actomyosin structure organization
|
GO:0031032 |
56 |
0.122
|
Mouse Worm Fly |
|
|
mapk cascade
|
GO:0000165 |
281 |
0.122
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
207 |
0.118
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.114
|
|
|
|
cardiocyte differentiation
|
GO:0035051 |
87 |
0.110
|
Human Mouse |
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.109
|
Fly |
|
|
developmental maturation
|
GO:0021700 |
193 |
0.108
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.107
|
|
|
|
phospholipase c activating g protein coupled receptor signaling pathway
|
GO:0007200 |
26 |
0.105
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.105
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
130 |
0.102
|
Human Mouse |
|
|
gland development
|
GO:0048732 |
330 |
0.101
|
Fly |
|
|
negative regulation of phagocytosis
|
GO:0050765 |
4 |
0.100
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.099
|
Mouse |
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.098
|
Fly |
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
119 |
0.098
|
|
|
|
regulation of actin filament length
|
GO:0030832 |
45 |
0.097
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.096
|
|
|
|
cardiac muscle cell differentiation
|
GO:0055007 |
69 |
0.095
|
Human Mouse |
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
54 |
0.093
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.093
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.092
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.091
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.091
|
|
|
|
regulation of blood pressure
|
GO:0008217 |
93 |
0.091
|
|
|
|
respiratory system development
|
GO:0060541 |
190 |
0.091
|
Fly |
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.089
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.087
|
|
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
73 |
0.086
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.085
|
Worm |
|
|
skin development
|
GO:0043588 |
220 |
0.083
|
Fly |
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.082
|
|
|
|
protein localization to membrane
|
GO:0072657 |
108 |
0.082
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.082
|
|
|
|
positive regulation of muscle contraction
|
GO:0045933 |
10 |
0.081
|
|
|
|
organic hydroxy compound transport
|
GO:0015850 |
93 |
0.081
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.081
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.080
|
Mouse |
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.078
|
Mouse |
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.078
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.077
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.075
|
Mouse |
|
|
second messenger mediated signaling
|
GO:0019932 |
73 |
0.074
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.074
|
Mouse |
|
|
heart contraction
|
GO:0060047 |
93 |
0.074
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.073
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.072
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.071
|
Mouse |
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.070
|
|
|
|
striated muscle contraction
|
GO:0006941 |
45 |
0.070
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.070
|
|
|
|
skeletal muscle thin filament assembly
|
GO:0030240 |
2 |
0.069
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.069
|
Mouse |
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.068
|
Mouse Worm Fly |
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.068
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.068
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.067
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.067
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.067
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.067
|
Mouse |
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.066
|
Mouse |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.066
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.066
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.064
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.064
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
116 |
0.064
|
Worm Fly |
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.064
|
Fly |
|
|
ossification
|
GO:0001503 |
216 |
0.064
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
81 |
0.063
|
|
|
|
heart process
|
GO:0003015 |
94 |
0.063
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.063
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.063
|
Mouse |
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.062
|
|
|
|
sarcomere organization
|
GO:0045214 |
24 |
0.062
|
Fly |
|
|
sequestering of calcium ion
|
GO:0051208 |
18 |
0.062
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.060
|
|
|
|
locomotory behavior
|
GO:0007626 |
195 |
0.060
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.060
|
|
|
|
cardiac cell development
|
GO:0055006 |
41 |
0.059
|
Human Mouse |
|
|
renal system development
|
GO:0072001 |
225 |
0.059
|
Fly |
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.059
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.059
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.059
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.058
|
Mouse |
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.058
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
92 |
0.058
|
|
|
|
cell cell junction organization
|
GO:0045216 |
72 |
0.058
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.058
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.057
|
Mouse |
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.055
|
Mouse |
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.055
|
|
|
|
striated muscle myosin thick filament assembly
|
GO:0071688 |
1 |
0.055
|
Worm |
|
|
blood circulation
|
GO:0008015 |
195 |
0.055
|
|
|
|
extracellular structure organization
|
GO:0043062 |
148 |
0.055
|
Human |
|
|
actin polymerization or depolymerization
|
GO:0008154 |
54 |
0.054
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.054
|
Mouse |
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.054
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.053
|
Fly |
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
139 |
0.053
|
Mouse Worm Fly |
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.053
|
Mouse Worm Fly |
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.053
|
Mouse |
|
|
branching involved in salivary gland morphogenesis
|
GO:0060445 |
26 |
0.052
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
86 |
0.052
|
Mouse |
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.051
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.051
|
Human Mouse Worm Fly |
|
|
cytokine production
|
GO:0001816 |
319 |
0.051
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.051
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.051
|
Mouse |
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.051
|
Mouse |
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.051
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.050
|
|
|
|
skeletal muscle fiber development
|
GO:0048741 |
58 |
0.050
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.049
|
|
|
|
fertilization
|
GO:0009566 |
127 |
0.049
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.049
|
Mouse |
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.049
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.049
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
65 |
0.049
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.048
|
Mouse |
|
|
dephosphorylation
|
GO:0016311 |
129 |
0.048
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.048
|
Mouse |
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.048
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.047
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.047
|
Mouse |
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.047
|
Mouse |
|
|
positive regulation of cell adhesion
|
GO:0045785 |
80 |
0.047
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.047
|
Mouse |
|
|
adenylate cyclase inhibiting g protein coupled receptor signaling pathway
|
GO:0007193 |
20 |
0.047
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.047
|
Fly |
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
159 |
0.047
|
Fly |
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.046
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.046
|
Mouse |
|
|
calcium ion transmembrane transport
|
GO:0070588 |
85 |
0.046
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.046
|
|
|
|
lung morphogenesis
|
GO:0060425 |
50 |
0.046
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.045
|
|
|
|
cardiac myofibril assembly
|
GO:0055003 |
12 |
0.045
|
Mouse |
|
|
synapse organization
|
GO:0050808 |
125 |
0.045
|
|
|
|
ear development
|
GO:0043583 |
200 |
0.045
|
|
|
|
tissue homeostasis
|
GO:0001894 |
115 |
0.045
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.044
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.044
|
|
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.044
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
132 |
0.043
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
71 |
0.043
|
|
|
|
actin mediated cell contraction
|
GO:0070252 |
15 |
0.043
|
|
|
|
exocrine system development
|
GO:0035272 |
45 |
0.043
|
Fly |
|
|
neuron projection extension
|
GO:1990138 |
64 |
0.042
|
|
|
|
monoamine transport
|
GO:0015844 |
33 |
0.042
|
|
|
|
fatty acid metabolic process
|
GO:0006631 |
121 |
0.042
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.041
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
53 |
0.041
|
|
|
|
extracellular matrix organization
|
GO:0030198 |
147 |
0.041
|
Human |
|
|
muscle fiber development
|
GO:0048747 |
76 |
0.041
|
Human |
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.041
|
Mouse |
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.041
|
Mouse |
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.041
|
|
|
|
myotube differentiation
|
GO:0014902 |
105 |
0.041
|
Mouse |
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
112 |
0.041
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.040
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.040
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.040
|
Mouse |
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
85 |
0.040
|
Mouse |
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.040
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
126 |
0.040
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.040
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.040
|
Fly |
|
|
positive regulation of angiogenesis
|
GO:0045766 |
46 |
0.040
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.039
|
|
|
|
skeletal myofibril assembly
|
GO:0014866 |
4 |
0.039
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.039
|
Mouse |
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.039
|
|
|
|
positive regulation of growth
|
GO:0045927 |
104 |
0.039
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
122 |
0.039
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.039
|
|
|
|
multicellular organismal response to stress
|
GO:0033555 |
62 |
0.039
|
|
|
|
regulation of systemic arterial blood pressure
|
GO:0003073 |
61 |
0.038
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.038
|
|
|
|
dopamine transport
|
GO:0015872 |
15 |
0.038
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.038
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.038
|
|
|
|
organ growth
|
GO:0035265 |
117 |
0.038
|
|
|
|
positive regulation of smooth muscle cell migration
|
GO:0014911 |
4 |
0.038
|
|
|
|
regulation of tube size
|
GO:0035150 |
57 |
0.037
|
Fly |
|
|
cell aging
|
GO:0007569 |
35 |
0.037
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
61 |
0.037
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.037
|
|
|
|
neuronal action potential
|
GO:0019228 |
54 |
0.037
|
|
|
|
cell maturation
|
GO:0048469 |
127 |
0.037
|
|
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.037
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
156 |
0.037
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.037
|
Mouse |
|
|
neuromuscular process
|
GO:0050905 |
99 |
0.037
|
Mouse |
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.037
|
|
|
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
80 |
0.037
|
Mouse |
|
|
cell substrate adhesion
|
GO:0031589 |
130 |
0.037
|
|
|
|
regulation of systemic arterial blood pressure mediated by a chemical signal
|
GO:0003044 |
33 |
0.036
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.036
|
|
|
|
heart morphogenesis
|
GO:0003007 |
178 |
0.036
|
|
|
|
positive regulation of chemotaxis
|
GO:0050921 |
38 |
0.035
|
|
|
|
synapse assembly
|
GO:0007416 |
56 |
0.035
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.035
|
Mouse |
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.035
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.035
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.034
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.034
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.034
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
169 |
0.034
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.034
|
|
|
|
myosin filament organization
|
GO:0031033 |
3 |
0.033
|
Worm Fly |
|
|
leukocyte chemotaxis
|
GO:0030595 |
69 |
0.033
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.033
|
Mouse |
|
|
germ cell development
|
GO:0007281 |
185 |
0.033
|
Fly |
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
82 |
0.033
|
|
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.033
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
64 |
0.033
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
93 |
0.033
|
|
|
|
striated muscle cell development
|
GO:0055002 |
125 |
0.033
|
Human Mouse Worm Fly |
|
|
regulation of transporter activity
|
GO:0032409 |
57 |
0.033
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.033
|
Mouse |
|
|
muscle cell fate specification
|
GO:0042694 |
1 |
0.032
|
|
|
|
actin filament polymerization
|
GO:0030041 |
44 |
0.032
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
69 |
0.032
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.032
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.032
|
Mouse |
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.032
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.032
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.032
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.032
|
|
|
|
regulation of neurotransmitter levels
|
GO:0001505 |
87 |
0.032
|
|
|
|
retinal blood vessel morphogenesis
|
GO:0061304 |
3 |
0.032
|
|
|
|
morphogenesis of a polarized epithelium
|
GO:0001738 |
37 |
0.032
|
Zebrafish |
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.031
|
Mouse |
|
|
phagocytosis
|
GO:0006909 |
66 |
0.031
|
|
|
|
sodium ion export
|
GO:0071436 |
2 |
0.031
|
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.031
|
Mouse |
|
|
elastic fiber assembly
|
GO:0048251 |
4 |
0.031
|
Human |
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.031
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.031
|
Mouse |
|
|
positive regulation of cell substrate adhesion
|
GO:0010811 |
47 |
0.031
|
|
|
|
response to oxidative stress
|
GO:0006979 |
123 |
0.030
|
|
|
|
response to oxygen levels
|
GO:0070482 |
62 |
0.030
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.030
|
|
|
|
response to insulin
|
GO:0032868 |
100 |
0.030
|
|
|
|
positive regulation of behavior
|
GO:0048520 |
40 |
0.030
|
|
|
|
heart trabecula formation
|
GO:0060347 |
14 |
0.030
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.030
|
|
|
|
potassium ion transport
|
GO:0006813 |
52 |
0.030
|
|
|
|
single fertilization
|
GO:0007338 |
82 |
0.030
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
128 |
0.029
|
|
|
|
rhythmic process
|
GO:0048511 |
174 |
0.029
|
|
|
|
regulation of cell shape
|
GO:0008360 |
39 |
0.029
|
Mouse Worm |
|
|
sodium ion transport
|
GO:0006814 |
73 |
0.029
|
|
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
45 |
0.029
|
|
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.029
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.029
|
|
|
|
positive regulation of ion transmembrane transport
|
GO:0034767 |
24 |
0.029
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.029
|
|
|
|
cell junction assembly
|
GO:0034329 |
52 |
0.029
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.028
|
|
|
|
connective tissue development
|
GO:0061448 |
179 |
0.028
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
88 |
0.028
|
|
|
|
cellular potassium ion transport
|
GO:0071804 |
43 |
0.028
|
|
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.028
|
|
|
|
multi multicellular organism process
|
GO:0044706 |
109 |
0.028
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.028
|
|
|
|
regulation of ossification
|
GO:0030278 |
112 |
0.028
|
|
|
|
salivary gland morphogenesis
|
GO:0007435 |
33 |
0.028
|
Fly |
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.028
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter involved in smooth muscle cell differentiation
|
GO:2000721 |
2 |
0.028
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.028
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.028
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.028
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
138 |
0.028
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.028
|
|
|
|
bone mineralization
|
GO:0030282 |
54 |
0.027
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.027
|
|
|
|
positive regulation of transmembrane transport
|
GO:0034764 |
29 |
0.027
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
179 |
0.027
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.027
|
Mouse |
|
|
negative regulation of cell migration
|
GO:0030336 |
59 |
0.027
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.027
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.027
|
Fly |
|
|
anion transport
|
GO:0006820 |
177 |
0.027
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.027
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
88 |
0.027
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.027
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.027
|
|
|
|
embryonic placenta development
|
GO:0001892 |
98 |
0.027
|
|
|
|
hair cycle
|
GO:0042633 |
90 |
0.027
|
|
|
|
myosin filament assembly
|
GO:0031034 |
2 |
0.027
|
Worm Fly |
|
|
regulation of protein secretion
|
GO:0050708 |
82 |
0.027
|
|
|
|
cardiac muscle fiber development
|
GO:0048739 |
4 |
0.026
|
Human |
|
|
gliogenesis
|
GO:0042063 |
141 |
0.026
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.026
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.026
|
Mouse |
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.026
|
|
|
|
meiotic cell cycle
|
GO:0051321 |
122 |
0.026
|
Mouse |
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.026
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.026
|
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.026
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.026
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.026
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.026
|
|
|
|
myelination
|
GO:0042552 |
74 |
0.025
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.025
|
|
|
|
digestion
|
GO:0007586 |
40 |
0.025
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
19 |
0.025
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.025
|
Mouse |
|
|
neuromuscular process controlling balance
|
GO:0050885 |
59 |
0.025
|
Mouse |
|
|
regulation of organ growth
|
GO:0046620 |
61 |
0.025
|
|
|
|
nucleoside monophosphate catabolic process
|
GO:0009125 |
59 |
0.025
|
Mouse |
|
|
female sex differentiation
|
GO:0046660 |
84 |
0.025
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.025
|
Mouse |
|
|
sodium ion export from cell
|
GO:0036376 |
1 |
0.025
|
|
|
|
myofibril assembly
|
GO:0030239 |
34 |
0.025
|
Mouse Worm Fly |
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.025
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.025
|
|
|
|
neurotransmitter transport
|
GO:0006836 |
76 |
0.024
|
|
|
|
biomineral tissue development
|
GO:0031214 |
64 |
0.024
|
|
|
|
regulation of heart contraction
|
GO:0008016 |
77 |
0.024
|
|
|
|
positive regulation of mitotic cell cycle
|
GO:0045931 |
41 |
0.024
|
|
|
|
regulation of receptor activity
|
GO:0010469 |
41 |
0.024
|
|
|
|
platelet activation
|
GO:0030168 |
40 |
0.024
|
|
|
|
myeloid leukocyte migration
|
GO:0097529 |
57 |
0.024
|
|
|
|
negative regulation of neuron death
|
GO:1901215 |
98 |
0.024
|
|
|
|
placenta development
|
GO:0001890 |
140 |
0.024
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
106 |
0.024
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.024
|
Mouse |
|
|
regulation of phagocytosis
|
GO:0050764 |
33 |
0.023
|
|
|
|
regulation of protein kinase b signaling
|
GO:0051896 |
56 |
0.023
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.023
|
Mouse Fly |
|
|
cellular response to insulin stimulus
|
GO:0032869 |
78 |
0.023
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.023
|
|
|
|
appendage development
|
GO:0048736 |
166 |
0.023
|
Fly |
|
|
hepaticobiliary system development
|
GO:0061008 |
67 |
0.023
|
|
|
|
blood coagulation
|
GO:0007596 |
76 |
0.023
|
|
|
|
tissue remodeling
|
GO:0048771 |
102 |
0.023
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.023
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.023
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.023
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.023
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.023
|
Mouse |
|
|
protein secretion
|
GO:0009306 |
111 |
0.023
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.023
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.022
|
|
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.022
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.022
|
|
|
|
adult behavior
|
GO:0030534 |
135 |
0.022
|
|
|
|
regulation of sodium ion transport
|
GO:0002028 |
29 |
0.022
|
|
|
|
purine nucleoside monophosphate metabolic process
|
GO:0009126 |
81 |
0.022
|
Mouse |
|
|
alcohol metabolic process
|
GO:0006066 |
116 |
0.022
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
119 |
0.022
|
|
|
|
brown fat cell differentiation
|
GO:0050873 |
36 |
0.022
|
|
|
|
protein targeting
|
GO:0006605 |
143 |
0.022
|
|
|
|
potassium ion transmembrane transport
|
GO:0071805 |
43 |
0.022
|
|
|
|
negative regulation of cell projection organization
|
GO:0031345 |
56 |
0.022
|
|
|
|
lipid transport
|
GO:0006869 |
98 |
0.022
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.022
|
|
|
|
regulation of heart growth
|
GO:0060420 |
31 |
0.022
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.022
|
|
|
|
regulation of blood vessel size
|
GO:0050880 |
56 |
0.022
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.022
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
61 |
0.022
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.022
|
Zebrafish Fly |
|
|
fibroblast growth factor receptor signaling pathway
|
GO:0008543 |
46 |
0.022
|
|
|
|
cell matrix adhesion
|
GO:0007160 |
68 |
0.022
|
|
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
103 |
0.021
|
|
|
|
protein polymerization
|
GO:0051258 |
57 |
0.021
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.021
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.021
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.021
|
Mouse |
|
|
chemotaxis
|
GO:0006935 |
247 |
0.021
|
Mouse |
|
|
hindbrain development
|
GO:0030902 |
128 |
0.021
|
Mouse |
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.021
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.021
|
|
|
|
salivary gland development
|
GO:0007431 |
37 |
0.021
|
Fly |
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.021
|
|
|
|
nephron morphogenesis
|
GO:0072028 |
69 |
0.021
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.021
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
71 |
0.021
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.021
|
|
|
|
ear morphogenesis
|
GO:0042471 |
118 |
0.021
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.021
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
74 |
0.021
|
|
|
|
ensheathment of neurons
|
GO:0007272 |
76 |
0.021
|
|
|
|
tissue migration
|
GO:0090130 |
68 |
0.021
|
Fly |
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.021
|
|
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
67 |
0.021
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.020
|
|
|
|
atp metabolic process
|
GO:0046034 |
75 |
0.020
|
Mouse |
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.020
|
|
|
|
vasoconstriction
|
GO:0042310 |
27 |
0.020
|
|
|
|
vascular process in circulatory system
|
GO:0003018 |
62 |
0.020
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.020
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.020
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
92 |
0.020
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.020
|
|
|
|
cilium morphogenesis
|
GO:0060271 |
102 |
0.020
|
|
|
|
male genitalia morphogenesis
|
GO:0048808 |
4 |
0.020
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.020
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.020
|
|
|
|
chronological cell aging
|
GO:0001300 |
1 |
0.020
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.020
|
|
|
|
muscle cell proliferation
|
GO:0033002 |
52 |
0.020
|
|
|
|
negative regulation of t cell activation
|
GO:0050868 |
65 |
0.020
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.019
|
Mouse |
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.019
|
Mouse |
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.019
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.019
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.019
|
|
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.019
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
93 |
0.019
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
47 |
0.019
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.019
|
|
|
|
cellular response to inorganic substance
|
GO:0071241 |
37 |
0.019
|
|
|
|
bone development
|
GO:0060348 |
120 |
0.019
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
69 |
0.019
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
87 |
0.019
|
|
|
|
cardiac chamber morphogenesis
|
GO:0003206 |
93 |
0.019
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.019
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.019
|
|
|
|
lipid localization
|
GO:0010876 |
126 |
0.019
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.019
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
71 |
0.019
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
68 |
0.019
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.019
|
Mouse |
|
|
sodium ion transmembrane transport
|
GO:0035725 |
49 |
0.019
|
|
|
|
cell growth
|
GO:0016049 |
130 |
0.019
|
|
|
|
regulation of organ morphogenesis
|
GO:2000027 |
144 |
0.019
|
Zebrafish |
|
|
hormone metabolic process
|
GO:0042445 |
86 |
0.019
|
|
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.019
|
|
|
|
female meiosis chromosome segregation
|
GO:0016321 |
1 |
0.019
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.019
|
|
|
|
regulation of cell growth
|
GO:0001558 |
91 |
0.019
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.018
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.018
|
|
