Mus musculus

72 known processes

Plk2

polo-like kinase 2 (Drosophila)

(Aliases: Snk)

Plk2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular amine metabolic process GO:0044106 44 0.163
amine metabolic process GO:0009308 45 0.137
regulation of cellular amine metabolic process GO:0033238 20 0.135
blood vessel morphogenesis GO:0048514 285 0.124
regulation of mapk cascade GO:0043408 248 0.111
cell adhesion GO:0007155 329 0.103
regulation of cell activation GO:0050865 289 0.100
axonogenesis GO:0007409 274 0.099
negative regulation of protein metabolic process GO:0051248 282 0.096
regulation of transferase activity GO:0051338 263 0.092
negative regulation of molecular function GO:0044092 258 0.091
regulation of cellular amino acid metabolic process GO:0006521 5 0.091
ribonucleotide metabolic process GO:0009259 291 0.089
synaptic transmission GO:0007268 329 0.085
small gtpase mediated signal transduction GO:0007264 97 0.085
Rat
mapk cascade GO:0000165 281 0.083
ribose phosphate metabolic process GO:0019693 291 0.082
purine containing compound metabolic process GO:0072521 311 0.079
ras protein signal transduction GO:0007265 77 0.078
Rat
nucleoside triphosphate catabolic process GO:0009143 205 0.078
nucleotide metabolic process GO:0009117 332 0.078
purine nucleotide metabolic process GO:0006163 302 0.076
negative regulation of cellular protein metabolic process GO:0032269 247 0.076
cellular amino acid metabolic process GO:0006520 103 0.072
purine ribonucleoside metabolic process GO:0046128 241 0.072
regulation of hydrolase activity GO:0051336 246 0.072
organic cyclic compound catabolic process GO:1901361 295 0.072
nucleoside phosphate metabolic process GO:0006753 338 0.071
regulation of kinase activity GO:0043549 249 0.069
aromatic compound catabolic process GO:0019439 286 0.069
glycosyl compound metabolic process GO:1901657 246 0.068
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.068
regulation of protein kinase activity GO:0045859 232 0.067
nucleobase containing small molecule metabolic process GO:0055086 352 0.066
regulation of neuron differentiation GO:0045664 281 0.065
Mouse Rat
purine nucleotide catabolic process GO:0006195 211 0.065
response to organonitrogen compound GO:0010243 246 0.064
cellular nitrogen compound catabolic process GO:0044270 280 0.063
purine nucleoside metabolic process GO:0042278 241 0.063
regulation of cell cycle GO:0051726 281 0.062
cellular ketone metabolic process GO:0042180 84 0.062
organophosphate catabolic process GO:0046434 232 0.062
regulation of cellular catabolic process GO:0031329 242 0.061
Rat
positive regulation of cell development GO:0010720 237 0.060
Mouse
response to radiation GO:0009314 165 0.060
ameboidal type cell migration GO:0001667 128 0.060
muscle tissue development GO:0060537 308 0.060
regulation of purine nucleotide metabolic process GO:1900542 169 0.059
response to growth factor GO:0070848 198 0.059
gtp catabolic process GO:0006184 143 0.058
ribonucleoside triphosphate catabolic process GO:0009203 199 0.058
positive regulation of protein phosphorylation GO:0001934 242 0.058
purine ribonucleotide catabolic process GO:0009154 208 0.058
regulation of cellular component biogenesis GO:0044087 181 0.056
Human
organonitrogen compound catabolic process GO:1901565 264 0.056
chemotaxis GO:0006935 247 0.056
regulation of cellular ketone metabolic process GO:0010565 66 0.056
purine nucleoside triphosphate catabolic process GO:0009146 203 0.055
purine nucleoside triphosphate metabolic process GO:0009144 226 0.054
purine ribonucleoside catabolic process GO:0046130 205 0.054
regulation of neuron projection development GO:0010975 169 0.053
Mouse Rat
apoptotic signaling pathway GO:0097190 306 0.053
heterocycle catabolic process GO:0046700 280 0.053
regulation of map kinase activity GO:0043405 120 0.052
regulation of cell motility GO:2000145 236 0.052
nucleoside metabolic process GO:0009116 246 0.052
organonitrogen compound biosynthetic process GO:1901566 192 0.051
inflammatory response GO:0006954 244 0.051
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.051
leukocyte differentiation GO:0002521 342 0.050
neuron projection guidance GO:0097485 141 0.049
purine containing compound catabolic process GO:0072523 213 0.049
regulation of cell migration GO:0030334 219 0.049
ribonucleoside triphosphate metabolic process GO:0009199 220 0.049
gtp metabolic process GO:0046039 144 0.049
positive regulation of cell death GO:0010942 224 0.048
carbohydrate derivative catabolic process GO:1901136 231 0.048
t cell activation GO:0042110 289 0.047
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.047
negative regulation of intracellular signal transduction GO:1902532 167 0.047
purine ribonucleotide metabolic process GO:0009150 290 0.047
cell type specific apoptotic process GO:0097285 268 0.047
Mouse
nucleoside triphosphate metabolic process GO:0009141 230 0.046
g protein coupled receptor signaling pathway GO:0007186 243 0.045
guanosine containing compound metabolic process GO:1901068 144 0.045
cellular lipid metabolic process GO:0044255 323 0.045
negative regulation of protein phosphorylation GO:0001933 126 0.045
regulation of peptidase activity GO:0052547 96 0.044
ribonucleotide catabolic process GO:0009261 208 0.044
positive regulation of mapk cascade GO:0043410 170 0.044
purine nucleoside catabolic process GO:0006152 205 0.043
regulation of nucleotide metabolic process GO:0006140 169 0.043
positive regulation of protein modification process GO:0031401 299 0.043
single organism cell adhesion GO:0098602 156 0.043
regulation of lymphocyte activation GO:0051249 240 0.043
leukocyte migration GO:0050900 124 0.043
homeostasis of number of cells GO:0048872 210 0.043
muscle cell differentiation GO:0042692 261 0.043
positive regulation of cellular catabolic process GO:0031331 148 0.042
Rat
nucleoside phosphate catabolic process GO:1901292 222 0.042
single organismal cell cell adhesion GO:0016337 131 0.042
negative regulation of phosphorus metabolic process GO:0010563 184 0.042
angiogenesis GO:0001525 201 0.042
guanosine containing compound catabolic process GO:1901069 144 0.042
regulation of anatomical structure size GO:0090066 178 0.042
action potential GO:0001508 78 0.041
regulation of protein serine threonine kinase activity GO:0071900 157 0.041
positive regulation of programmed cell death GO:0043068 218 0.041
multicellular organismal signaling GO:0035637 91 0.041
transmission of nerve impulse GO:0019226 76 0.041
peptidyl amino acid modification GO:0018193 336 0.041
locomotory behavior GO:0007626 195 0.041
positive regulation of cellular amine metabolic process GO:0033240 5 0.040
axon guidance GO:0007411 141 0.040
mitotic cell cycle process GO:1903047 159 0.040
membrane organization GO:0061024 245 0.040
glial cell differentiation GO:0010001 131 0.040
jnk cascade GO:0007254 72 0.039
regulation of leukocyte differentiation GO:1902105 159 0.039
lymphocyte differentiation GO:0030098 242 0.039
blood circulation GO:0008015 195 0.039
nucleoside catabolic process GO:0009164 206 0.039
neuronal action potential GO:0019228 54 0.039
regulation of cell projection organization GO:0031344 206 0.039
Mouse Rat
nucleotide catabolic process GO:0009166 217 0.039
dna metabolic process GO:0006259 303 0.039
Yeast
glycosyl compound catabolic process GO:1901658 206 0.039
cation transport GO:0006812 399 0.039
cell growth GO:0016049 130 0.038
positive regulation of apoptotic process GO:0043065 217 0.038
striated muscle tissue development GO:0014706 293 0.038
developmental maturation GO:0021700 193 0.038
regulation of cell adhesion GO:0030155 154 0.038
epithelial cell proliferation GO:0050673 174 0.038
skin development GO:0043588 220 0.037
ribonucleoside metabolic process GO:0009119 245 0.037
regulation of apoptotic signaling pathway GO:2001233 197 0.037
cell substrate adhesion GO:0031589 130 0.037
ribonucleoside catabolic process GO:0042454 206 0.036
transmembrane transport GO:0055085 412 0.036
positive regulation of proteolysis GO:0045862 85 0.036
Rat
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.036
digestive system development GO:0055123 200 0.035
immune effector process GO:0002252 321 0.035
positive regulation of cell migration GO:0030335 109 0.035
negative regulation of phosphate metabolic process GO:0045936 184 0.035
wound healing GO:0042060 157 0.034
negative regulation of protein modification process GO:0031400 163 0.034
circulatory system process GO:0003013 197 0.034
regulation of cellular response to stress GO:0080135 159 0.034
forebrain development GO:0030900 302 0.034
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.033
response to organic cyclic compound GO:0014070 198 0.033
positive regulation of neuron projection development GO:0010976 79 0.033
Mouse
dendrite development GO:0016358 115 0.033
Rat
regulation of membrane potential GO:0042391 192 0.033
regulation of t cell activation GO:0050863 170 0.033
protein catabolic process GO:0030163 221 0.033
Rat
regulation of organelle organization GO:0033043 289 0.033
Human Yeast
skeletal system development GO:0001501 356 0.033
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.033
t cell differentiation GO:0030217 174 0.033
cellular response to dna damage stimulus GO:0006974 207 0.033
Mouse
digestive tract development GO:0048565 190 0.032
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.032
gland development GO:0048732 330 0.032
positive regulation of hydrolase activity GO:0051345 148 0.032
innate immune response GO:0045087 157 0.032
response to light stimulus GO:0009416 135 0.032
cellular response to cytokine stimulus GO:0071345 189 0.032
myeloid cell differentiation GO:0030099 233 0.032
regulation of response to wounding GO:1903034 189 0.032
cellular response to organonitrogen compound GO:0071417 145 0.032
endocytosis GO:0006897 168 0.031
regulation of nucleotide catabolic process GO:0030811 122 0.031
regulation of defense response GO:0031347 233 0.031
positive regulation of cell motility GO:2000147 116 0.031
regulation of ovulation GO:0060278 3 0.031
fat cell differentiation GO:0045444 160 0.031
gastrulation GO:0007369 116 0.030
skeletal system morphogenesis GO:0048705 203 0.030
camera type eye development GO:0043010 266 0.030
canonical wnt signaling pathway GO:0060070 130 0.030
actin cytoskeleton organization GO:0030036 220 0.030
negative regulation of response to wounding GO:1903035 77 0.030
cellular homeostasis GO:0019725 240 0.029
regulation of wnt signaling pathway GO:0030111 123 0.029
rho protein signal transduction GO:0007266 32 0.029
developmental growth involved in morphogenesis GO:0060560 138 0.029
negative regulation of phosphorylation GO:0042326 166 0.029
carbohydrate derivative biosynthetic process GO:1901137 183 0.029
regulation of vasculature development GO:1901342 88 0.029
cellular response to growth factor stimulus GO:0071363 197 0.028
ossification GO:0001503 216 0.028
regulation of purine nucleotide catabolic process GO:0033121 122 0.028
extrinsic apoptotic signaling pathway GO:0097191 126 0.028
cytokine production GO:0001816 319 0.028
digestive tract morphogenesis GO:0048546 147 0.028
wnt signaling pathway GO:0016055 188 0.028
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.028
embryonic organ morphogenesis GO:0048562 276 0.027
regulation of cytokine production GO:0001817 266 0.027
positive regulation of protein kinase activity GO:0045860 144 0.027
regulation of inflammatory response GO:0050727 147 0.027
skeletal muscle organ development GO:0060538 163 0.027
organelle localization GO:0051640 179 0.027
response to extracellular stimulus GO:0009991 127 0.027
lipid biosynthetic process GO:0008610 179 0.027
positive regulation of nucleotide metabolic process GO:0045981 114 0.027
engulfment of apoptotic cell GO:0043652 3 0.027
striated muscle cell development GO:0055002 125 0.027
multicellular organismal homeostasis GO:0048871 164 0.026
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.026
regulation of system process GO:0044057 200 0.026
cell matrix adhesion GO:0007160 68 0.026
cellular macromolecule catabolic process GO:0044265 206 0.026
Rat
negative regulation of cellular component organization GO:0051129 194 0.026
Rat
cell chemotaxis GO:0060326 81 0.026
regionalization GO:0003002 337 0.026
regulation of ras gtpase activity GO:0032318 88 0.026
regulation of cytoskeleton organization GO:0051493 122 0.026
Human Yeast
organelle fission GO:0048285 170 0.026
Yeast
regulation of epithelial cell proliferation GO:0050678 141 0.026
ion transmembrane transport GO:0034220 361 0.026
negative regulation of cell proliferation GO:0008285 296 0.026
Mouse
regulation of cellular component size GO:0032535 121 0.026
negative regulation of immune system process GO:0002683 209 0.026
rhythmic process GO:0048511 174 0.026
divalent metal ion transport GO:0070838 172 0.026
positive regulation of cell projection organization GO:0031346 95 0.025
Mouse
renal system development GO:0072001 225 0.025
negative regulation of kinase activity GO:0033673 81 0.025
germ cell development GO:0007281 185 0.025
sensory organ morphogenesis GO:0090596 242 0.025
cellular chemical homeostasis GO:0055082 215 0.025
response to lipopolysaccharide GO:0032496 128 0.025
spermatogenesis GO:0007283 284 0.024
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.024
neuron death GO:0070997 154 0.024
microtubule based process GO:0007017 236 0.024
Human Yeast
response to nutrient levels GO:0031667 109 0.024
carboxylic acid transport GO:0046942 100 0.024
cell division GO:0051301 120 0.024
negative regulation of transferase activity GO:0051348 85 0.024
regulation of multi organism process GO:0043900 111 0.024
regulation of ion transport GO:0043269 215 0.024
regulation of cellular response to growth factor stimulus GO:0090287 82 0.024
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.024
cellular response to lipid GO:0071396 145 0.024
regulation of protein localization GO:0032880 231 0.024
cytokine mediated signaling pathway GO:0019221 115 0.023
anatomical structure homeostasis GO:0060249 145 0.023
regulation of gtp catabolic process GO:0033124 113 0.023
heart morphogenesis GO:0003007 178 0.023
oxidation reduction process GO:0055114 342 0.023
positive regulation of cell activation GO:0050867 158 0.023
rap protein signal transduction GO:0032486 3 0.023
Rat
positive regulation of gtp catabolic process GO:0033126 85 0.023
circadian rhythm GO:0007623 114 0.023
regulation of body fluid levels GO:0050878 162 0.023
regulation of lymphocyte differentiation GO:0045619 107 0.023
synapse organization GO:0050808 125 0.023
muscle system process GO:0003012 141 0.023
hemostasis GO:0007599 78 0.023
positive regulation of lymphocyte activation GO:0051251 140 0.023
epidermis development GO:0008544 187 0.022
organic anion transport GO:0015711 137 0.022
organophosphate biosynthetic process GO:0090407 122 0.022
negative regulation of neuron death GO:1901215 98 0.022
response to transforming growth factor beta GO:0071559 88 0.022
bmp signaling pathway GO:0030509 93 0.022
response to molecule of bacterial origin GO:0002237 143 0.022
neuron apoptotic process GO:0051402 142 0.022
hematopoietic progenitor cell differentiation GO:0002244 143 0.022
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.022
leukocyte proliferation GO:0070661 172 0.022
regulation of nucleoside metabolic process GO:0009118 130 0.022
regulation of reactive oxygen species metabolic process GO:2000377 40 0.022
reactive oxygen species metabolic process GO:0072593 84 0.022
regulation of blood pressure GO:0008217 93 0.022
regulation of cell growth GO:0001558 91 0.021
male gamete generation GO:0048232 285 0.021
regulation of proteolysis GO:0030162 164 0.021
Rat
mitotic cell cycle GO:0000278 195 0.021
regulation of cell cycle process GO:0010564 160 0.021
myeloid cell homeostasis GO:0002262 114 0.021
organic acid transport GO:0015849 101 0.021
nitrogen compound transport GO:0071705 271 0.021
epithelial cell migration GO:0010631 63 0.021
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.021
posttranscriptional regulation of gene expression GO:0010608 155 0.021
negative regulation of defense response GO:0031348 77 0.021
positive regulation of phospholipase activity GO:0010518 3 0.021
central nervous system neuron differentiation GO:0021953 162 0.021
positive regulation of leukocyte differentiation GO:1902107 86 0.021
regulation of ras protein signal transduction GO:0046578 114 0.021
multicellular organism growth GO:0035264 161 0.021
regulation of secretion GO:0051046 274 0.020
cellular protein complex assembly GO:0043623 116 0.020
gliogenesis GO:0042063 141 0.020
glycoprotein metabolic process GO:0009100 116 0.020
cellular response to extracellular stimulus GO:0031668 81 0.020
protein maturation GO:0051604 176 0.020
positive regulation of kinase activity GO:0033674 155 0.020
negative regulation of hydrolase activity GO:0051346 71 0.020
macromolecule catabolic process GO:0009057 281 0.020
Rat
anion transport GO:0006820 177 0.020
regulation of canonical wnt signaling pathway GO:0060828 82 0.020
neuromuscular process controlling balance GO:0050885 59 0.020
regulation of organ morphogenesis GO:2000027 144 0.020
sphingolipid biosynthetic process GO:0030148 26 0.020
regulation of lipid metabolic process GO:0019216 118 0.020
negative regulation of cell development GO:0010721 169 0.020
Rat
protein modification by small protein conjugation GO:0032446 187 0.020
regulation of neuron death GO:1901214 134 0.020
negative regulation of cellular amine metabolic process GO:0033239 1 0.020
developmental cell growth GO:0048588 84 0.020
ensheathment of neurons GO:0007272 76 0.020
maintenance of location GO:0051235 89 0.019
organic hydroxy compound metabolic process GO:1901615 203 0.019
cellular response to molecule of bacterial origin GO:0071219 83 0.019
cellular response to hormone stimulus GO:0032870 150 0.019
multi multicellular organism process GO:0044706 109 0.019
sphingolipid metabolic process GO:0006665 45 0.019
cell recognition GO:0008037 83 0.019
fertilization GO:0009566 127 0.019
cation homeostasis GO:0055080 212 0.019
sensory perception GO:0007600 245 0.019
respiratory tube development GO:0030323 167 0.019
lateral inhibition GO:0046331 1 0.019
stem cell differentiation GO:0048863 268 0.019
heart contraction GO:0060047 93 0.019
erk1 and erk2 cascade GO:0070371 77 0.019
peptidyl tyrosine modification GO:0018212 145 0.019
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.019
telencephalon development GO:0021537 186 0.019
cellular response to lipopolysaccharide GO:0071222 77 0.019
asymmetric neuroblast division GO:0055059 1 0.018
cation transmembrane transport GO:0098655 266 0.018
small molecule biosynthetic process GO:0044283 132 0.018
regulation of neuron apoptotic process GO:0043523 122 0.018
cellular ion homeostasis GO:0006873 165 0.018
protein modification by small protein conjugation or removal GO:0070647 207 0.018
microtubule cytoskeleton organization GO:0000226 157 0.018
Human Yeast
mesenchyme development GO:0060485 152 0.018
epithelial tube morphogenesis GO:0060562 303 0.018
positive regulation of nervous system development GO:0051962 221 0.018
Mouse
cardiac chamber development GO:0003205 108 0.018
response to insulin GO:0032868 100 0.018
positive regulation of transferase activity GO:0051347 167 0.018
cell fate commitment GO:0045165 210 0.018
fibrinolysis GO:0042730 3 0.018
response to peptide hormone GO:0043434 127 0.018
placenta development GO:0001890 140 0.018
negative regulation of cell activation GO:0050866 111 0.018
positive regulation of secretion by cell GO:1903532 114 0.018
nerve development GO:0021675 67 0.018
cognition GO:0050890 149 0.018
cytoplasmic transport GO:0016482 234 0.018
metal ion homeostasis GO:0055065 189 0.018
heart process GO:0003015 94 0.018
regulation of secretion by cell GO:1903530 249 0.017
positive regulation of cell adhesion GO:0045785 80 0.017
nuclear division GO:0000280 158 0.017
Yeast
inorganic ion transmembrane transport GO:0098660 234 0.017
intracellular protein transport GO:0006886 204 0.017
actin filament organization GO:0007015 113 0.017
monocarboxylic acid metabolic process GO:0032787 191 0.017
adaptive immune response GO:0002250 155 0.017
phagocytosis GO:0006909 66 0.017
positive regulation of cytokine production GO:0001819 174 0.017
sensory system development GO:0048880 3 0.017
cell junction organization GO:0034330 77 0.017
respiratory system development GO:0060541 190 0.017
negative regulation of immune effector process GO:0002698 55 0.017
organelle assembly GO:0070925 177 0.017
Human Yeast
divalent inorganic cation transport GO:0072511 178 0.017
gonad development GO:0008406 141 0.017
regulation of cell substrate adhesion GO:0010810 73 0.017
response to inorganic substance GO:0010035 96 0.017
response to peptide GO:1901652 136 0.017
adult behavior GO:0030534 135 0.017
cellular metal ion homeostasis GO:0006875 151 0.017
cellular response to external stimulus GO:0071496 88 0.017
negative regulation of proteolysis GO:0045861 74 0.017
carbohydrate metabolic process GO:0005975 230 0.016
cellular protein catabolic process GO:0044257 155 0.016
Rat
protein ubiquitination GO:0016567 171 0.016
negative regulation of growth GO:0045926 99 0.016
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.016
cellular response to biotic stimulus GO:0071216 92 0.016
regulation of cell size GO:0008361 72 0.016
stress activated protein kinase signaling cascade GO:0031098 81 0.016
positive regulation of organelle organization GO:0010638 128 0.016
Yeast
regulation of transmembrane transport GO:0034762 128 0.016
positive regulation of growth GO:0045927 104 0.016
regulation of cysteine type endopeptidase activity GO:2000116 65 0.016
stem cell development GO:0048864 219 0.016
establishment of organelle localization GO:0051656 122 0.016
positive regulation of nucleotide catabolic process GO:0030813 88 0.016
epithelial cell development GO:0002064 159 0.016
monosaccharide transport GO:0015749 58 0.016
tissue homeostasis GO:0001894 115 0.016
defense response to other organism GO:0098542 197 0.016
immune response activating signal transduction GO:0002757 116 0.016
lipid transport GO:0006869 98 0.016
tissue migration GO:0090130 68 0.016
retina development in camera type eye GO:0060041 119 0.016
connective tissue development GO:0061448 179 0.016
regulation of endopeptidase activity GO:0052548 89 0.016
regulation of homeostatic process GO:0032844 182 0.016
tube formation GO:0035148 140 0.016
regulation of extent of cell growth GO:0061387 52 0.016
myotube differentiation GO:0014902 105 0.016
regulation of angiogenesis GO:0045765 81 0.016
reactive nitrogen species metabolic process GO:2001057 0 0.016
regulation of jnk cascade GO:0046328 62 0.016
positive regulation of secretion GO:0051047 130 0.016
regulation of leukocyte apoptotic process GO:2000106 56 0.016
cellular response to peptide GO:1901653 92 0.016
leukocyte chemotaxis GO:0030595 69 0.016
rna processing GO:0006396 105 0.016
axon ensheathment GO:0008366 76 0.016
morphogenesis of embryonic epithelium GO:0016331 159 0.016
reactive oxygen species biosynthetic process GO:1903409 8 0.016
regulation of striated muscle cell differentiation GO:0051153 81 0.016
protein localization to organelle GO:0033365 185 0.015
b cell activation GO:0042113 161 0.015
peptidyl tyrosine phosphorylation GO:0018108 143 0.015
lymphocyte proliferation GO:0046651 164 0.015
cell junction assembly GO:0034329 52 0.015
cellular response to acid chemical GO:0071229 68 0.015
extracellular structure organization GO:0043062 148 0.015
mesoderm development GO:0007498 100 0.015
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.015
sequestering of metal ion GO:0051238 19 0.015
muscle cell development GO:0055001 133 0.015
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.015
myelination GO:0042552 74 0.015
cardiac muscle tissue development GO:0048738 130 0.015
nephron development GO:0072006 109 0.015
regulation of protein catabolic process GO:0042176 108 0.015
Rat
leukocyte homeostasis GO:0001776 79 0.015
leukocyte apoptotic process GO:0071887 71 0.015
positive regulation of cellular component biogenesis GO:0044089 94 0.015
carbohydrate homeostasis GO:0033500 128 0.015
regulation of fat cell differentiation GO:0045598 81 0.015
regulation of ion transmembrane transport GO:0034765 119 0.015
positive regulation of t cell activation GO:0050870 101 0.015
response to acid chemical GO:0001101 111 0.015
blood coagulation GO:0007596 76 0.015
learning GO:0007612 98 0.015
negative regulation of apoptotic signaling pathway GO:2001234 104 0.015
pallium development GO:0021543 120 0.015
glucose homeostasis GO:0042593 128 0.015
embryonic placenta development GO:0001892 98 0.015
regulation of vesicle mediated transport GO:0060627 139 0.015
membrane lipid metabolic process GO:0006643 53 0.015
negative regulation of lymphocyte activation GO:0051250 91 0.015
regulation of protein maturation GO:1903317 96 0.015
glycerolipid metabolic process GO:0046486 122 0.015
carbohydrate transport GO:0008643 62 0.015
positive regulation of nucleoside metabolic process GO:0045979 91 0.015
activation of immune response GO:0002253 138 0.014
epithelium migration GO:0090132 63 0.014
compound eye development GO:0048749 1 0.014
stress activated mapk cascade GO:0051403 80 0.014
meiotic cell cycle GO:0051321 122 0.014
Yeast
glycoprotein biosynthetic process GO:0009101 89 0.014
mesodermal cell migration GO:0008078 4 0.014
negative regulation of neuron apoptotic process GO:0043524 92 0.014
purine ribonucleotide biosynthetic process GO:0009152 59 0.014
negative regulation of protein processing GO:0010955 79 0.014
cellular calcium ion homeostasis GO:0006874 119 0.014
positive regulation of neuron differentiation GO:0045666 141 0.014
Mouse
neuromuscular process GO:0050905 99 0.014
retrograde transport endosome to golgi GO:0042147 2 0.014
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.014
regulation of protein transport GO:0051223 163 0.014
divalent inorganic cation homeostasis GO:0072507 138 0.014
negative regulation of organelle organization GO:0010639 90 0.014
cellular divalent inorganic cation homeostasis GO:0072503 127 0.014
urogenital system development GO:0001655 261 0.014
regulation of metal ion transport GO:0010959 106 0.014
protein processing GO:0016485 163 0.014
actin polymerization or depolymerization GO:0008154 54 0.014
modification dependent macromolecule catabolic process GO:0043632 133 0.014
Rat
dephosphorylation GO:0016311 129 0.014
neural precursor cell proliferation GO:0061351 121 0.014

Plk2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.045
nervous system disease DOID:863 0 0.045
disease of cellular proliferation DOID:14566 0 0.021
organ system cancer DOID:0050686 0 0.018
cancer DOID:162 0 0.018
central nervous system disease DOID:331 0 0.017
sensory system disease DOID:0050155 0 0.015