Mus musculus

32 known processes

Ocrl

oculocerebrorenal syndrome of Lowe

(Aliases: OCRL1,9530014D17Rik,BB143339)

Ocrl biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular nitrogen compound catabolic process GO:0044270 280 0.061
Human
ras protein signal transduction GO:0007265 77 0.059
organonitrogen compound catabolic process GO:1901565 264 0.056
Human
ribonucleotide metabolic process GO:0009259 291 0.054
Human
purine containing compound metabolic process GO:0072521 311 0.052
Human
heterocycle catabolic process GO:0046700 280 0.050
Human
organic cyclic compound catabolic process GO:1901361 295 0.049
Human
carbohydrate derivative catabolic process GO:1901136 231 0.048
Human
organophosphate catabolic process GO:0046434 232 0.047
Human
transmembrane transport GO:0055085 412 0.047
purine nucleoside catabolic process GO:0006152 205 0.046
Human
glycosyl compound catabolic process GO:1901658 206 0.045
Human
dna metabolic process GO:0006259 303 0.045
glycosyl compound metabolic process GO:1901657 246 0.044
Human
purine containing compound catabolic process GO:0072523 213 0.044
Human
purine nucleotide catabolic process GO:0006195 211 0.043
Human
purine nucleoside triphosphate metabolic process GO:0009144 226 0.043
Human
small gtpase mediated signal transduction GO:0007264 97 0.043
purine nucleotide metabolic process GO:0006163 302 0.042
Human
nucleoside metabolic process GO:0009116 246 0.042
Human
ribonucleoside triphosphate catabolic process GO:0009203 199 0.041
Human
purine ribonucleotide metabolic process GO:0009150 290 0.041
Human
amine metabolic process GO:0009308 45 0.040
nitrogen compound transport GO:0071705 271 0.040
cellular amine metabolic process GO:0044106 44 0.040
aromatic compound catabolic process GO:0019439 286 0.040
Human
nucleoside phosphate metabolic process GO:0006753 338 0.039
Human
regulation of cellular amino acid metabolic process GO:0006521 5 0.039
ion transmembrane transport GO:0034220 361 0.039
posttranscriptional regulation of gene expression GO:0010608 155 0.038
nucleotide catabolic process GO:0009166 217 0.037
Human
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.037
Human
ribonucleoside catabolic process GO:0042454 206 0.037
Human
regulation of cellular amine metabolic process GO:0033238 20 0.037
ribonucleoside metabolic process GO:0009119 245 0.037
Human
nucleoside phosphate catabolic process GO:1901292 222 0.036
Human
purine nucleoside metabolic process GO:0042278 241 0.036
Human
purine ribonucleoside metabolic process GO:0046128 241 0.036
Human
cation transmembrane transport GO:0098655 266 0.036
nucleoside catabolic process GO:0009164 206 0.036
Human
nucleobase containing small molecule metabolic process GO:0055086 352 0.036
Human
ribose phosphate metabolic process GO:0019693 291 0.035
Human
skeletal system development GO:0001501 356 0.035
cation transport GO:0006812 399 0.035
protein modification by small protein conjugation or removal GO:0070647 207 0.034
macromolecule catabolic process GO:0009057 281 0.033
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.033
Human
inorganic cation transmembrane transport GO:0098662 207 0.032
regulation of neuron differentiation GO:0045664 281 0.031
purine ribonucleotide catabolic process GO:0009154 208 0.030
Human
protein ubiquitination GO:0016567 171 0.030
apoptotic signaling pathway GO:0097190 306 0.030
purine ribonucleoside catabolic process GO:0046130 205 0.030
Human
ribonucleoside triphosphate metabolic process GO:0009199 220 0.029
Human
cellular amino acid metabolic process GO:0006520 103 0.029
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.029
Mouse
camera type eye development GO:0043010 266 0.028
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.028
forebrain development GO:0030900 302 0.028
nucleoside triphosphate metabolic process GO:0009141 230 0.028
Human
nucleoside triphosphate catabolic process GO:0009143 205 0.028
Human
endocytosis GO:0006897 168 0.028
Fly
intracellular protein transport GO:0006886 204 0.027
Mouse
regulation of protein localization GO:0032880 231 0.026
modification dependent protein catabolic process GO:0019941 133 0.026
guanosine containing compound metabolic process GO:1901068 144 0.026
Human
inorganic ion transmembrane transport GO:0098660 234 0.026
membrane organization GO:0061024 245 0.026
Mouse
positive regulation of cellular amine metabolic process GO:0033240 5 0.026
protein modification by small protein conjugation GO:0032446 187 0.025
regulation of apoptotic signaling pathway GO:2001233 197 0.025
embryonic organ morphogenesis GO:0048562 276 0.025
oxidation reduction process GO:0055114 342 0.024
Mouse
cellular ketone metabolic process GO:0042180 84 0.024
cell type specific apoptotic process GO:0097285 268 0.024
chromatin organization GO:0006325 206 0.024
cellular macromolecule catabolic process GO:0044265 206 0.024
ribonucleotide catabolic process GO:0009261 208 0.023
Human
regulation of secretion by cell GO:1903530 249 0.023
mapk cascade GO:0000165 281 0.023
divalent inorganic cation transport GO:0072511 178 0.023
cellular homeostasis GO:0019725 240 0.023
protein catabolic process GO:0030163 221 0.023
response to organic cyclic compound GO:0014070 198 0.023
Mouse
hematopoietic progenitor cell differentiation GO:0002244 143 0.023
regulation of transferase activity GO:0051338 263 0.022
Mouse
dna repair GO:0006281 107 0.022
organelle localization GO:0051640 179 0.022
purine nucleoside triphosphate catabolic process GO:0009146 203 0.022
Human
cellular ion homeostasis GO:0006873 165 0.022
divalent metal ion transport GO:0070838 172 0.022
organonitrogen compound biosynthetic process GO:1901566 192 0.022
protein localization to organelle GO:0033365 185 0.022
leukocyte differentiation GO:0002521 342 0.021
male gamete generation GO:0048232 285 0.021
Mouse
negative regulation of cell development GO:0010721 169 0.021
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.021
anion transport GO:0006820 177 0.020
regulation of secretion GO:0051046 274 0.020
cytoplasmic transport GO:0016482 234 0.020
nucleoside monophosphate metabolic process GO:0009123 85 0.020
positive regulation of cellular catabolic process GO:0031331 148 0.020
Human
methylation GO:0032259 134 0.020
regulation of cellular ketone metabolic process GO:0010565 66 0.020
g protein coupled receptor signaling pathway GO:0007186 243 0.020
Mouse
positive regulation of protein phosphorylation GO:0001934 242 0.020
sensory perception GO:0007600 245 0.019
regulation of translation GO:0006417 71 0.019
synaptic transmission GO:0007268 329 0.019
positive regulation of protein modification process GO:0031401 299 0.019
sensory organ morphogenesis GO:0090596 242 0.019
regulation of organelle organization GO:0033043 289 0.019
Fly
regulation of anatomical structure size GO:0090066 178 0.019
regulation of nucleoside metabolic process GO:0009118 130 0.019
Human
nucleotide metabolic process GO:0009117 332 0.018
Human
translation GO:0006412 93 0.018
blood circulation GO:0008015 195 0.018
exocytosis GO:0006887 121 0.018
response to organonitrogen compound GO:0010243 246 0.018
Mouse
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.018
immune effector process GO:0002252 321 0.018
urogenital system development GO:0001655 261 0.018
respiratory system development GO:0060541 190 0.018
organic anion transport GO:0015711 137 0.018
modification dependent macromolecule catabolic process GO:0043632 133 0.017
chemotaxis GO:0006935 247 0.017
carbohydrate derivative biosynthetic process GO:1901137 183 0.017
circulatory system process GO:0003013 197 0.017
cellular chemical homeostasis GO:0055082 215 0.017
cellular component assembly involved in morphogenesis GO:0010927 139 0.017
Human
learning or memory GO:0007611 148 0.017
organic hydroxy compound metabolic process GO:1901615 203 0.017
muscle system process GO:0003012 141 0.017
cilium assembly GO:0042384 81 0.017
Human
protein maturation GO:0051604 176 0.017
Mouse
regulation of kinase activity GO:0043549 249 0.017
maintenance of location GO:0051235 89 0.017
protein targeting GO:0006605 143 0.017
Mouse
cognition GO:0050890 149 0.017
positive regulation of nervous system development GO:0051962 221 0.017
lateral inhibition GO:0046331 1 0.017
cellular response to organonitrogen compound GO:0071417 145 0.016
Mouse
regulation of purine nucleotide metabolic process GO:1900542 169 0.016
Human
ubiquitin dependent protein catabolic process GO:0006511 129 0.016
organic acid transport GO:0015849 101 0.016
chromatin modification GO:0016568 187 0.016
cellular protein catabolic process GO:0044257 155 0.016
compound eye development GO:0048749 1 0.016
retrograde transport endosome to golgi GO:0042147 2 0.016
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.016
Human
regulation of intracellular transport GO:0032386 159 0.016
regulation of membrane potential GO:0042391 192 0.016
germ cell development GO:0007281 185 0.016
regulation of proteolysis GO:0030162 164 0.016
positive regulation of transferase activity GO:0051347 167 0.016
protein polyubiquitination GO:0000209 33 0.016
ear development GO:0043583 200 0.016
regulation of mapk cascade GO:0043408 248 0.016
muscle cell differentiation GO:0042692 261 0.016
negative regulation of protein metabolic process GO:0051248 282 0.016
Mouse
gland development GO:0048732 330 0.016
regulation of hydrolase activity GO:0051336 246 0.016
Human
positive regulation of gtp catabolic process GO:0033126 85 0.015
Human
calcium ion transport GO:0006816 159 0.015
regionalization GO:0003002 337 0.015
reactive oxygen species metabolic process GO:0072593 84 0.015
regulation of ion transport GO:0043269 215 0.015
establishment or maintenance of cell polarity GO:0007163 86 0.015
carboxylic acid transport GO:0046942 100 0.015
cellular lipid metabolic process GO:0044255 323 0.015
regulation of cellular catabolic process GO:0031329 242 0.015
Human
endomembrane system organization GO:0010256 147 0.015
Mouse
epithelial tube morphogenesis GO:0060562 303 0.015
negative regulation of intracellular signal transduction GO:1902532 167 0.015
Mouse
cell fate commitment GO:0045165 210 0.015
t cell activation GO:0042110 289 0.015
morphogenesis of a branching structure GO:0001763 203 0.015
cytokine production GO:0001816 319 0.015
mitotic cell cycle GO:0000278 195 0.015
positive regulation of mapk cascade GO:0043410 170 0.015
regulation of purine nucleotide catabolic process GO:0033121 122 0.015
Human
regulation of multi organism process GO:0043900 111 0.015
regulation of establishment of protein localization GO:0070201 181 0.015
regulation of nucleotide catabolic process GO:0030811 122 0.015
Human
ribonucleoside monophosphate metabolic process GO:0009161 80 0.015
developmental maturation GO:0021700 193 0.015
purine nucleoside monophosphate metabolic process GO:0009126 81 0.015
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.014
carbohydrate metabolic process GO:0005975 230 0.014
Mouse
skeletal system morphogenesis GO:0048705 203 0.014
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.014
Human
protein import GO:0017038 101 0.014
cilium morphogenesis GO:0060271 102 0.014
Human
rho protein signal transduction GO:0007266 32 0.014
spermatid differentiation GO:0048515 115 0.014
locomotory behavior GO:0007626 195 0.014
positive regulation of kinase activity GO:0033674 155 0.014
proteasomal protein catabolic process GO:0010498 98 0.014
blood vessel morphogenesis GO:0048514 285 0.014
multicellular organism growth GO:0035264 161 0.014
telencephalon development GO:0021537 186 0.014
microtubule based process GO:0007017 236 0.014
regulation of cytokine production GO:0001817 266 0.014
synapse organization GO:0050808 125 0.014
regulation of cell cycle GO:0051726 281 0.014
Fly
regulation of gtp catabolic process GO:0033124 113 0.014
Human
carbohydrate homeostasis GO:0033500 128 0.014
Mouse
golgi to endosome transport GO:0006895 3 0.014
histone modification GO:0016570 159 0.014
cellular calcium ion homeostasis GO:0006874 119 0.013
atp metabolic process GO:0046034 75 0.013
fertilization GO:0009566 127 0.013
cellular response to organic cyclic compound GO:0071407 87 0.013
Mouse
protein alkylation GO:0008213 81 0.013
regulation of protein kinase activity GO:0045859 232 0.013
muscle tissue development GO:0060537 308 0.013
nuclear transport GO:0051169 139 0.013
nucleocytoplasmic transport GO:0006913 139 0.013
response to radiation GO:0009314 165 0.013
response to growth factor GO:0070848 198 0.013
multicellular organismal signaling GO:0035637 91 0.013
regulation of cellular component biogenesis GO:0044087 181 0.013
Fly
negative regulation of cellular amine metabolic process GO:0033239 1 0.013
calcium ion transmembrane transport GO:0070588 85 0.013
metal ion homeostasis GO:0055065 189 0.013
glucose homeostasis GO:0042593 128 0.013
Mouse
lymphocyte differentiation GO:0030098 242 0.013
spermatogenesis GO:0007283 284 0.013
Mouse
anatomical structure homeostasis GO:0060249 145 0.013
cellular response to lipid GO:0071396 145 0.013
cellular response to growth factor stimulus GO:0071363 197 0.013
regulation of system process GO:0044057 200 0.013
Mouse
glycoprotein metabolic process GO:0009100 116 0.013
acetylcholine transport GO:0015870 2 0.013
macromolecule methylation GO:0043414 120 0.013
organelle assembly GO:0070925 177 0.013
Human
negative regulation of molecular function GO:0044092 258 0.013
Mouse
positive regulation of protein kinase activity GO:0045860 144 0.012
morphogenesis of a branching epithelium GO:0061138 193 0.012
cation homeostasis GO:0055080 212 0.012
gtp metabolic process GO:0046039 144 0.012
Human
regulation of cellular response to stress GO:0080135 159 0.012
homeostasis of number of cells GO:0048872 210 0.012
regulation of vesicle mediated transport GO:0060627 139 0.012
regulation of hormone levels GO:0010817 211 0.012
central nervous system neuron differentiation GO:0021953 162 0.012
positive regulation of cell development GO:0010720 237 0.012
regulation of protein serine threonine kinase activity GO:0071900 157 0.012
regulation of transmembrane transport GO:0034762 128 0.012
sensory perception of sound GO:0007605 97 0.012
gtp catabolic process GO:0006184 143 0.012
Human
cellular metal ion homeostasis GO:0006875 151 0.012
cellular response to hormone stimulus GO:0032870 150 0.012
Mouse
anion transmembrane transport GO:0098656 71 0.012
negative regulation of cellular protein metabolic process GO:0032269 247 0.012
Mouse
negative regulation of nervous system development GO:0051961 156 0.012
regulation of lymphocyte activation GO:0051249 240 0.012
regulation of protein transport GO:0051223 163 0.012
cellular response to dna damage stimulus GO:0006974 207 0.012
fat cell differentiation GO:0045444 160 0.012
response to light stimulus GO:0009416 135 0.012
positive regulation of programmed cell death GO:0043068 218 0.012
cell division GO:0051301 120 0.012
Fly
ear morphogenesis GO:0042471 118 0.012
sensory perception of mechanical stimulus GO:0050954 107 0.012
regulation of body fluid levels GO:0050878 162 0.012
Mouse
epithelial cell development GO:0002064 159 0.012
regulation of cell activation GO:0050865 289 0.012
peptidyl amino acid modification GO:0018193 336 0.012
Mouse
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.012
transmission of nerve impulse GO:0019226 76 0.012
purine nucleoside monophosphate catabolic process GO:0009128 58 0.012
response to inorganic substance GO:0010035 96 0.012
protein localization to nucleus GO:0034504 121 0.012
establishment of protein localization to organelle GO:0072594 118 0.012
actin cytoskeleton organization GO:0030036 220 0.012
Fly
regulation of cell motility GO:2000145 236 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.012
protein localization to membrane GO:0072657 108 0.012
Mouse
guanosine containing compound catabolic process GO:1901069 144 0.011
Human
regulation of ras protein signal transduction GO:0046578 114 0.011
Human
positive regulation of hydrolase activity GO:0051345 148 0.011
Human
negative regulation of synapse assembly GO:0051964 3 0.011
single organism nuclear import GO:1902593 95 0.011
regulation of t cell activation GO:0050863 170 0.011
limb development GO:0060173 166 0.011
establishment of vesicle localization GO:0051650 81 0.011
atp catabolic process GO:0006200 55 0.011
dna modification GO:0006304 50 0.011
organic hydroxy compound transport GO:0015850 93 0.011
cellular protein complex assembly GO:0043623 116 0.011
regulation of nucleotide metabolic process GO:0006140 169 0.011
Human
divalent inorganic cation homeostasis GO:0072507 138 0.011
regulation of actin nucleation GO:0051125 4 0.011
sensory system development GO:0048880 3 0.011
renal system development GO:0072001 225 0.011
regulation of defense response GO:0031347 233 0.011
nuclear import GO:0051170 95 0.011
regulation of map kinase activity GO:0043405 120 0.011
neuron death GO:0070997 154 0.011
positive regulation of cell death GO:0010942 224 0.011
regulation of ion transmembrane transport GO:0034765 119 0.011
positive regulation of nucleoside metabolic process GO:0045979 91 0.011
Human
neuronal action potential GO:0019228 54 0.011
regulation of neuron projection development GO:0010975 169 0.011
organelle fission GO:0048285 170 0.011
striated muscle tissue development GO:0014706 293 0.011
skeletal muscle organ development GO:0060538 163 0.011
organic acid biosynthetic process GO:0016053 86 0.011
protein polymerization GO:0051258 57 0.011
cardiac muscle contraction GO:0060048 32 0.011
positive regulation of organelle organization GO:0010638 128 0.011
negative regulation of cell proliferation GO:0008285 296 0.011
response to peptide hormone GO:0043434 127 0.011
Mouse
negative regulation of cell activation GO:0050866 111 0.011
regulation of protein catabolic process GO:0042176 108 0.011
monocarboxylic acid metabolic process GO:0032787 191 0.011
regulation of cell projection organization GO:0031344 206 0.011
lipid transport GO:0006869 98 0.011
vacuole organization GO:0007033 38 0.011
spermatid development GO:0007286 108 0.011
lung development GO:0030324 164 0.011
t cell differentiation GO:0030217 174 0.011
cellular divalent inorganic cation homeostasis GO:0072503 127 0.011
establishment of organelle localization GO:0051656 122 0.010
morphogenesis of embryonic epithelium GO:0016331 159 0.010
action potential GO:0001508 78 0.010
dna alkylation GO:0006305 43 0.010
regulation of cell cycle process GO:0010564 160 0.010
Fly
regulation of neuron death GO:1901214 134 0.010
vesicle localization GO:0051648 86 0.010
epithelial cell proliferation GO:0050673 174 0.010
heart morphogenesis GO:0003007 178 0.010
retina development in camera type eye GO:0060041 119 0.010
amino acid transport GO:0006865 61 0.010
digestive tract development GO:0048565 190 0.010
sequestering of metal ion GO:0051238 19 0.010
positive regulation of neuron differentiation GO:0045666 141 0.010
regulation of neurotransmitter levels GO:0001505 87 0.010
carboxylic acid biosynthetic process GO:0046394 86 0.010
myosin filament assembly GO:0031034 2 0.010
regulation of endocytosis GO:0030100 69 0.010
inner ear morphogenesis GO:0042472 101 0.010
small molecule catabolic process GO:0044282 71 0.010
membrane tubulation GO:0097320 4 0.010
kidney development GO:0001822 213 0.010
cellular response to molecule of bacterial origin GO:0071219 83 0.010
response to acid chemical GO:0001101 111 0.010
positive regulation of nucleotide catabolic process GO:0030813 88 0.010
Human

Ocrl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.031
nervous system disease DOID:863 0 0.031
disease of metabolism DOID:0014667 0 0.021
inherited metabolic disorder DOID:655 0 0.021
immune system disease DOID:2914 0 0.012
neuromuscular disease DOID:440 0 0.011
neuropathy DOID:870 0 0.011
musculoskeletal system disease DOID:17 0 0.011
connective tissue disease DOID:65 0 0.010
disease of mental health DOID:150 0 0.010
central nervous system disease DOID:331 0 0.010