Mus musculus

57 known processes

Sptlc2

serine palmitoyltransferase, long chain base subunit 2

(Aliases: LCB2,AI173915,mKIAA0526)

Sptlc2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
sphingolipid biosynthetic process GO:0030148 26 0.685
membrane lipid biosynthetic process GO:0046467 32 0.458
sphingolipid metabolic process GO:0006665 45 0.347
membrane lipid metabolic process GO:0006643 53 0.264
amine metabolic process GO:0009308 45 0.261
cellular amine metabolic process GO:0044106 44 0.259
apoptotic signaling pathway GO:0097190 306 0.234
organonitrogen compound biosynthetic process GO:1901566 192 0.227
regulation of apoptotic signaling pathway GO:2001233 197 0.221
positive regulation of cell death GO:0010942 224 0.217
transmembrane transport GO:0055085 412 0.205
regulation of cellular amine metabolic process GO:0033238 20 0.193
regulation of cellular amino acid metabolic process GO:0006521 5 0.168
ion transmembrane transport GO:0034220 361 0.166
cellular amino acid metabolic process GO:0006520 103 0.156
defense response to bacterium GO:0042742 119 0.144
lipid transport GO:0006869 98 0.135
regulation of cellular ketone metabolic process GO:0010565 66 0.129
regulation of homeostatic process GO:0032844 182 0.128
positive regulation of apoptotic signaling pathway GO:2001235 95 0.123
positive regulation of programmed cell death GO:0043068 218 0.119
cellular lipid metabolic process GO:0044255 323 0.117
peptidyl amino acid modification GO:0018193 336 0.115
peptidyl tyrosine phosphorylation GO:0018108 143 0.114
defense response to other organism GO:0098542 197 0.110
cellular response to lipopolysaccharide GO:0071222 77 0.106
homeostasis of number of cells GO:0048872 210 0.104
immune effector process GO:0002252 321 0.104
cation homeostasis GO:0055080 212 0.099
protein processing GO:0016485 163 0.098
cellular ketone metabolic process GO:0042180 84 0.097
cation transport GO:0006812 399 0.096
positive regulation of cellular amine metabolic process GO:0033240 5 0.085
carbohydrate derivative biosynthetic process GO:1901137 183 0.084
protein maturation GO:0051604 176 0.083
response to organonitrogen compound GO:0010243 246 0.081
negative regulation of cellular protein metabolic process GO:0032269 247 0.079
cellular response to hormone stimulus GO:0032870 150 0.079
ras protein signal transduction GO:0007265 77 0.079
mapk cascade GO:0000165 281 0.077
anion transport GO:0006820 177 0.076
immune response activating signal transduction GO:0002757 116 0.076
myeloid cell differentiation GO:0030099 233 0.075
organic anion transport GO:0015711 137 0.075
negative regulation of protein metabolic process GO:0051248 282 0.074
extrinsic apoptotic signaling pathway GO:0097191 126 0.074
calcium ion transport GO:0006816 159 0.071
response to organic cyclic compound GO:0014070 198 0.071
regulation of t cell activation GO:0050863 170 0.070
membrane organization GO:0061024 245 0.069
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 34 0.068
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.067
positive regulation of protein phosphorylation GO:0001934 242 0.067
adaptive immune response GO:0002250 155 0.067
negative regulation of lymphocyte activation GO:0051250 91 0.064
cellular chemical homeostasis GO:0055082 215 0.064
negative regulation of molecular function GO:0044092 258 0.064
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.064
leukocyte apoptotic process GO:0071887 71 0.064
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.064
regulation of defense response GO:0031347 233 0.063
response to growth factor GO:0070848 198 0.063
cellular protein catabolic process GO:0044257 155 0.062
organic hydroxy compound transport GO:0015850 93 0.061
cellular response to lipid GO:0071396 145 0.060
leukocyte homeostasis GO:0001776 79 0.060
regulation of cell activation GO:0050865 289 0.059
organic acid transport GO:0015849 101 0.059
nitrogen compound transport GO:0071705 271 0.058
regulation of ion transport GO:0043269 215 0.057
inflammatory response GO:0006954 244 0.057
small molecule biosynthetic process GO:0044283 132 0.057
positive regulation of ion transport GO:0043270 65 0.057
cellular response to growth factor stimulus GO:0071363 197 0.056
endocytosis GO:0006897 168 0.056
very long chain fatty acid biosynthetic process GO:0042761 2 0.055
cellular response to cytokine stimulus GO:0071345 189 0.055
carboxylic acid transport GO:0046942 100 0.053
t cell activation GO:0042110 289 0.052
regulation of cytokine production GO:0001817 266 0.052
cellular macromolecule catabolic process GO:0044265 206 0.051
divalent inorganic cation transport GO:0072511 178 0.050
regulation of membrane potential GO:0042391 192 0.050
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.050
regulation of binding GO:0051098 111 0.049
regulation of mapk cascade GO:0043408 248 0.049
leukocyte differentiation GO:0002521 342 0.049
cellular response to molecule of bacterial origin GO:0071219 83 0.047
negative regulation of cellular amine metabolic process GO:0033239 1 0.047
fatty acid elongation unsaturated fatty acid GO:0019368 2 0.047
response to acid chemical GO:0001101 111 0.046
small gtpase mediated signal transduction GO:0007264 97 0.046
cytoplasmic transport GO:0016482 234 0.046
cytokine production GO:0001816 319 0.045
negative regulation of t cell activation GO:0050868 65 0.045
rho protein signal transduction GO:0007266 32 0.045
t cell differentiation GO:0030217 174 0.044
striated muscle tissue development GO:0014706 293 0.044
protein localization to membrane GO:0072657 108 0.044
positive regulation of protein modification process GO:0031401 299 0.044
positive regulation of apoptotic process GO:0043065 217 0.044
cation transmembrane transport GO:0098655 266 0.043
peptidyl tyrosine modification GO:0018212 145 0.043
regulation of protein complex assembly GO:0043254 83 0.043
wound healing GO:0042060 157 0.043
regulation of proteolysis GO:0030162 164 0.042
skin development GO:0043588 220 0.042
norepinephrine transport GO:0015874 2 0.042
negative regulation of phosphate metabolic process GO:0045936 184 0.042
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.042
fatty acid elongation GO:0030497 3 0.042
regulation of transferase activity GO:0051338 263 0.041
positive regulation of organelle organization GO:0010638 128 0.041
macromolecule catabolic process GO:0009057 281 0.040
cell type specific apoptotic process GO:0097285 268 0.040
regulation of lymphocyte proliferation GO:0050670 117 0.040
organophosphate biosynthetic process GO:0090407 122 0.040
very long chain fatty acid metabolic process GO:0000038 8 0.040
response to molecule of bacterial origin GO:0002237 143 0.039
ribose phosphate metabolic process GO:0019693 291 0.039
retrograde transport endosome to golgi GO:0042147 2 0.039
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.038
regulation of secretion GO:0051046 274 0.038
regulation of response to wounding GO:1903034 189 0.038
cell activation involved in immune response GO:0002263 126 0.038
leukocyte mediated immunity GO:0002443 174 0.037
lipid biosynthetic process GO:0008610 179 0.037
divalent metal ion transport GO:0070838 172 0.037
positive regulation of secretion by cell GO:1903532 114 0.037
regulation of actin cytoskeleton organization GO:0032956 84 0.037
immune response regulating signaling pathway GO:0002764 125 0.037
interferon beta biosynthetic process GO:0045350 4 0.036
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.036
monocarboxylic acid metabolic process GO:0032787 191 0.036
vacuole organization GO:0007033 38 0.036
regulation of peptidase activity GO:0052547 96 0.036
hormone metabolic process GO:0042445 86 0.036
regulation of calcium ion transport GO:0051924 69 0.035
response to lipopolysaccharide GO:0032496 128 0.035
cellular homeostasis GO:0019725 240 0.035
negative regulation of protein modification process GO:0031400 163 0.035
ossification GO:0001503 216 0.035
myeloid cell homeostasis GO:0002262 114 0.035
spermatogenesis GO:0007283 284 0.035
leukocyte proliferation GO:0070661 172 0.034
vesicle organization GO:0016050 60 0.034
actin polymerization or depolymerization GO:0008154 54 0.033
organonitrogen compound catabolic process GO:1901565 264 0.033
regulation of cell cycle GO:0051726 281 0.033
carboxylic acid biosynthetic process GO:0046394 86 0.033
regulation of hormone levels GO:0010817 211 0.033
metal ion homeostasis GO:0055065 189 0.033
purine nucleotide metabolic process GO:0006163 302 0.033
positive regulation of secretion GO:0051047 130 0.033
organelle fission GO:0048285 170 0.033
cellular ion homeostasis GO:0006873 165 0.032
sequestering of calcium ion GO:0051208 18 0.032
negative regulation of immune system process GO:0002683 209 0.032
skeletal system development GO:0001501 356 0.031
synaptic transmission GO:0007268 329 0.031
amide transport GO:0042886 138 0.031
nucleoside phosphate metabolic process GO:0006753 338 0.031
regulation of vesicle mediated transport GO:0060627 139 0.031
negative regulation of apoptotic signaling pathway GO:2001234 104 0.031
protein catabolic process GO:0030163 221 0.030
regulation of cytoskeleton organization GO:0051493 122 0.030
activation of mapkkk activity GO:0000185 1 0.030
organic hydroxy compound metabolic process GO:1901615 203 0.030
regulation of reactive oxygen species metabolic process GO:2000377 40 0.030
nucleobase containing small molecule metabolic process GO:0055086 352 0.030
negative regulation of cytokine production GO:0001818 84 0.029
cellular response to organonitrogen compound GO:0071417 145 0.029
b cell activation GO:0042113 161 0.029
regulation of leukocyte differentiation GO:1902105 159 0.029
fatty acid metabolic process GO:0006631 121 0.029
cellular metal ion homeostasis GO:0006875 151 0.029
inorganic ion transmembrane transport GO:0098660 234 0.028
cellular response to biotic stimulus GO:0071216 92 0.028
endomembrane system organization GO:0010256 147 0.028
maintenance of location GO:0051235 89 0.028
Worm
lipid localization GO:0010876 126 0.028
Worm
secondary metabolic process GO:0019748 18 0.028
nucleotide metabolic process GO:0009117 332 0.028
regulation of ion transmembrane transport GO:0034765 119 0.028
negative regulation of intracellular signal transduction GO:1902532 167 0.028
negative regulation of cell activation GO:0050866 111 0.028
protein localization to organelle GO:0033365 185 0.028
regulation of metal ion transport GO:0010959 106 0.028
cytokine mediated signaling pathway GO:0019221 115 0.028
multicellular organismal signaling GO:0035637 91 0.028
regulation of purine nucleotide metabolic process GO:1900542 169 0.027
cellular protein complex assembly GO:0043623 116 0.027
peptide transport GO:0015833 133 0.027
regulation of protein maturation GO:1903317 96 0.027
alpha beta t cell differentiation GO:0046632 69 0.027
peptide secretion GO:0002790 114 0.027
interspecies interaction between organisms GO:0044419 83 0.027
ribonucleotide metabolic process GO:0009259 291 0.027
interleukin 8 production GO:0032637 4 0.027
carbohydrate homeostasis GO:0033500 128 0.027
cell fate commitment GO:0045165 210 0.026
regulation of cell adhesion GO:0030155 154 0.026
sequestering of metal ion GO:0051238 19 0.026
protein polymerization GO:0051258 57 0.026
calcium ion homeostasis GO:0055074 127 0.026
purine nucleoside metabolic process GO:0042278 241 0.026
negative regulation of phosphorus metabolic process GO:0010563 184 0.026
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.026
cellular calcium ion homeostasis GO:0006874 119 0.026
divalent inorganic cation homeostasis GO:0072507 138 0.026
regulation of secretion by cell GO:1903530 249 0.025
actin cytoskeleton reorganization GO:0031532 21 0.025
myeloid leukocyte activation GO:0002274 83 0.025
regulation of lymphocyte activation GO:0051249 240 0.025
protein targeting GO:0006605 143 0.025
intrinsic apoptotic signaling pathway GO:0097193 132 0.025
activation of immune response GO:0002253 138 0.025
engulfment of apoptotic cell GO:0043652 3 0.025
regulation of actin filament based process GO:0032970 99 0.025
inorganic cation transmembrane transport GO:0098662 207 0.025
protein localization to nucleus GO:0034504 121 0.024
monosaccharide metabolic process GO:0005996 106 0.024
lymphocyte differentiation GO:0030098 242 0.024
organelle assembly GO:0070925 177 0.024
regulation of inflammatory response GO:0050727 147 0.024
locomotory behavior GO:0007626 195 0.024
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.024
posttranscriptional regulation of gene expression GO:0010608 155 0.024
muscle cell development GO:0055001 133 0.024
positive regulation of cytokine production GO:0001819 174 0.024
ceramide metabolic process GO:0006672 31 0.024
fatty acid biosynthetic process GO:0006633 41 0.023
regulation of interleukin 8 production GO:0032677 3 0.023
carbohydrate metabolic process GO:0005975 230 0.023
action potential GO:0001508 78 0.023
glycosyl compound metabolic process GO:1901657 246 0.023
hexose metabolic process GO:0019318 98 0.023
respiratory tube development GO:0030323 167 0.023
regulation of intracellular transport GO:0032386 159 0.023
regulation of actin filament polymerization GO:0030833 38 0.023
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.023
negative regulation of protein phosphorylation GO:0001933 126 0.023
anion transmembrane transport GO:0098656 71 0.023
intracellular protein transport GO:0006886 204 0.023
cellular response to organic cyclic compound GO:0071407 87 0.023
actin cytoskeleton organization GO:0030036 220 0.022
pigmentation GO:0043473 71 0.022
blood coagulation GO:0007596 76 0.022
regulation of protein localization GO:0032880 231 0.022
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.022
response to drug GO:0042493 75 0.022
regulation of t cell proliferation GO:0042129 92 0.022
purine ribonucleotide metabolic process GO:0009150 290 0.022
positive regulation of nucleotide metabolic process GO:0045981 114 0.022
response to endoplasmic reticulum stress GO:0034976 53 0.022
regulation of interferon beta biosynthetic process GO:0045357 4 0.022
regulation of ion transmembrane transporter activity GO:0032412 54 0.022
leukocyte activation involved in immune response GO:0002366 126 0.022
signal transduction in absence of ligand GO:0038034 55 0.022
lymphocyte proliferation GO:0046651 164 0.022
cell adhesion GO:0007155 329 0.022
organic cyclic compound catabolic process GO:1901361 295 0.022
carbohydrate derivative catabolic process GO:1901136 231 0.021
cellular divalent inorganic cation homeostasis GO:0072503 127 0.021
nucleocytoplasmic transport GO:0006913 139 0.021
response to amino acid GO:0043200 37 0.021
dephosphorylation GO:0016311 129 0.021
alpha beta t cell activation GO:0046631 91 0.021
angiogenesis GO:0001525 201 0.021
germ cell development GO:0007281 185 0.021
regulation of norepinephrine secretion GO:0014061 2 0.021
innate immune response GO:0045087 157 0.021
positive regulation of interferon alpha production GO:0032727 4 0.021
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.021
positive regulation of homeostatic process GO:0032846 64 0.021
positive regulation of protein complex assembly GO:0031334 45 0.021
protein import into nucleus GO:0006606 95 0.021
regulation of system process GO:0044057 200 0.021
regulation of protein transport GO:0051223 163 0.021
regulation of hemostasis GO:1900046 28 0.021
gonad development GO:0008406 141 0.020
purine containing compound metabolic process GO:0072521 311 0.020
nucleoside phosphate catabolic process GO:1901292 222 0.020
regulation of cellular response to stress GO:0080135 159 0.020
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.020
sa node cell action potential GO:0086015 4 0.020
learning or memory GO:0007611 148 0.020
stem cell differentiation GO:0048863 268 0.020
regulation of organelle organization GO:0033043 289 0.020
positive regulation of cell activation GO:0050867 158 0.020
leukocyte migration GO:0050900 124 0.020
negative regulation of protein maturation GO:1903318 79 0.020
epidermis development GO:0008544 187 0.020
single organism nuclear import GO:1902593 95 0.020
phagocytosis GO:0006909 66 0.020
nucleoside metabolic process GO:0009116 246 0.020
monocarboxylic acid biosynthetic process GO:0072330 61 0.019
response to nutrient levels GO:0031667 109 0.019
sensory organ morphogenesis GO:0090596 242 0.019
protein modification by small protein conjugation GO:0032446 187 0.019
modification dependent protein catabolic process GO:0019941 133 0.019
arp2 3 complex mediated actin nucleation GO:0034314 3 0.019
protein import GO:0017038 101 0.019
regulation of protein processing GO:0070613 96 0.019
nuclear transport GO:0051169 139 0.019
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.019
positive regulation of cellular component biogenesis GO:0044089 94 0.019
cellular response to acid chemical GO:0071229 68 0.019
coagulation GO:0050817 78 0.019
myeloid leukocyte differentiation GO:0002573 119 0.019
regulation of protein kinase activity GO:0045859 232 0.019
regulation of t cell differentiation GO:0045580 83 0.019
t cell apoptotic process GO:0070231 39 0.019
actin filament polymerization GO:0030041 44 0.019
response to radiation GO:0009314 165 0.019
skeletal system morphogenesis GO:0048705 203 0.018
regulation of exit from mitosis GO:0007096 1 0.018
positive regulation of hydrolase activity GO:0051345 148 0.018
lymphocyte activation involved in immune response GO:0002285 93 0.018
regulation of endopeptidase activity GO:0052548 89 0.018
blood circulation GO:0008015 195 0.018
cellular response to steroid hormone stimulus GO:0071383 33 0.018
multi organism behavior GO:0051705 62 0.018
actin filament organization GO:0007015 113 0.018
positive regulation of proteolysis GO:0045862 85 0.018
positive regulation of calcium ion transport GO:0051928 27 0.018
positive regulation of intracellular transport GO:0032388 70 0.018
nuclear division GO:0000280 158 0.018
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.018
regulation of cellular component biogenesis GO:0044087 181 0.018
sterol transport GO:0015918 38 0.018
development of primary sexual characteristics GO:0045137 143 0.018
peptide hormone secretion GO:0030072 109 0.018
monocarboxylic acid transport GO:0015718 44 0.018
norepinephrine secretion GO:0048243 2 0.018
organelle localization GO:0051640 179 0.018
tissue homeostasis GO:0001894 115 0.018
regulation of neutrophil apoptotic process GO:0033029 1 0.018
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.018
sensory perception GO:0007600 245 0.018
lymphocyte apoptotic process GO:0070227 54 0.018
purine ribonucleoside metabolic process GO:0046128 241 0.018
regulation of transmembrane transport GO:0034762 128 0.018
nucleoside triphosphate catabolic process GO:0009143 205 0.018
protein localization to plasma membrane GO:0072659 57 0.017
compound eye development GO:0048749 1 0.017
cellular response to monosaccharide stimulus GO:0071326 47 0.017
response to transforming growth factor beta GO:0071559 88 0.017
circulatory system process GO:0003013 197 0.017
acid secretion GO:0046717 33 0.017
cell division GO:0051301 120 0.017
respiratory system development GO:0060541 190 0.017
response to extracellular stimulus GO:0009991 127 0.017
camera type eye development GO:0043010 266 0.017
macromolecule methylation GO:0043414 120 0.017
cytokinetic process GO:0032506 2 0.017
negative regulation of interleukin 8 secretion GO:2000483 1 0.017
developmental maturation GO:0021700 193 0.017
chromatin organization GO:0006325 206 0.017
purine containing compound catabolic process GO:0072523 213 0.017
gonad morphogenesis GO:0035262 1 0.017
negative regulation of peptidase activity GO:0010466 46 0.017
chromatin modification GO:0016568 187 0.017
negative regulation of cell proliferation GO:0008285 296 0.017
spermatid differentiation GO:0048515 115 0.017
methylation GO:0032259 134 0.017
forebrain development GO:0030900 302 0.017
muscle cell differentiation GO:0042692 261 0.017
ubiquitin dependent protein catabolic process GO:0006511 129 0.017
regulation of cell migration GO:0030334 219 0.016
regulation of cell motility GO:2000145 236 0.016
nucleoside triphosphate metabolic process GO:0009141 230 0.016
glycoprotein metabolic process GO:0009100 116 0.016
embryonic organ morphogenesis GO:0048562 276 0.016
male gamete generation GO:0048232 285 0.016
response to decreased oxygen levels GO:0036293 59 0.016
exocytosis GO:0006887 121 0.016
lateral inhibition GO:0046331 1 0.016
digestive system development GO:0055123 200 0.016
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.016
regulation of multi organism process GO:0043900 111 0.016
regulation of leukocyte apoptotic process GO:2000106 56 0.016
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.016
purine ribonucleotide biosynthetic process GO:0009152 59 0.016
negative regulation of leukocyte differentiation GO:1902106 51 0.016
regulation of protein import into nucleus GO:0042306 52 0.016
heterocycle catabolic process GO:0046700 280 0.016
fibrinolysis GO:0042730 3 0.016
positive regulation of neutrophil apoptotic process GO:0033031 1 0.016
regulation of lymphocyte apoptotic process GO:0070228 41 0.016
muscle tissue development GO:0060537 308 0.016
modification dependent macromolecule catabolic process GO:0043632 133 0.016
response to monosaccharide GO:0034284 67 0.016
regulation of synaptic plasticity GO:0048167 87 0.016
ameboidal type cell migration GO:0001667 128 0.016
response to peptide hormone GO:0043434 127 0.016
negative regulation of phosphorylation GO:0042326 166 0.016
regulation of leukocyte proliferation GO:0070663 121 0.016
immunoglobulin mediated immune response GO:0016064 69 0.016
membrane fusion GO:0061025 38 0.016
regulation of cellular catabolic process GO:0031329 242 0.016
reactive oxygen species metabolic process GO:0072593 84 0.015
hormone secretion GO:0046879 128 0.015
peptidyl serine phosphorylation GO:0018105 74 0.015
dna metabolic process GO:0006259 303 0.015
aromatic compound catabolic process GO:0019439 286 0.015
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.015
ribonucleoside metabolic process GO:0009119 245 0.015
single organism cell adhesion GO:0098602 156 0.015
limb development GO:0060173 166 0.015
regulation of hydrolase activity GO:0051336 246 0.015
actin mediated cell contraction GO:0070252 15 0.015
regulation of innate immune response GO:0045088 91 0.015
response to dexamethasone GO:0071548 8 0.015
regulation of neuron death GO:1901214 134 0.015
regulation of ras protein signal transduction GO:0046578 114 0.015
sulfur compound metabolic process GO:0006790 100 0.015
regulation of neuron differentiation GO:0045664 281 0.015
cellular response to abiotic stimulus GO:0071214 56 0.015
macrophage differentiation GO:0030225 20 0.015
oocyte axis specification GO:0007309 2 0.015
epinephrine transport GO:0048241 1 0.015
lung development GO:0030324 164 0.015
regulation of kinase activity GO:0043549 249 0.015
protein methylation GO:0006479 81 0.015
negative regulation of proteolysis GO:0045861 74 0.015
regulation of calcium ion transport into cytosol GO:0010522 31 0.015
response to peptide GO:1901652 136 0.015
cellular response to external stimulus GO:0071496 88 0.014
negative regulation of protein processing GO:0010955 79 0.014
neuron apoptotic process GO:0051402 142 0.014
cellular pigmentation GO:0033059 20 0.014
interleukin 2 mediated signaling pathway GO:0038110 2 0.014
multicellular organismal homeostasis GO:0048871 164 0.014
sensory perception of sound GO:0007605 97 0.014
alcohol metabolic process GO:0006066 116 0.014
nucleotide catabolic process GO:0009166 217 0.014
plasma membrane organization GO:0007009 90 0.014
protein oligomerization GO:0051259 67 0.014
purine nucleoside catabolic process GO:0006152 205 0.014
cellular response to interleukin 15 GO:0071350 2 0.014
blood vessel morphogenesis GO:0048514 285 0.014
regulation of cell projection organization GO:0031344 206 0.014
t cell mediated immunity GO:0002456 50 0.014
nucleotide biosynthetic process GO:0009165 78 0.014
vesicle localization GO:0051648 86 0.014
cellular nitrogen compound catabolic process GO:0044270 280 0.014
morphogenesis of embryonic epithelium GO:0016331 159 0.014
cytokine biosynthetic process GO:0042089 68 0.014
asymmetric stem cell division GO:0098722 3 0.014
microtubule cytoskeleton organization GO:0000226 157 0.014
muscle contraction GO:0006936 101 0.014
regulation of ossification GO:0030278 112 0.014
regulation of peptide secretion GO:0002791 77 0.014
insulin secretion GO:0030073 89 0.014
glucose metabolic process GO:0006006 92 0.014
fatty acid elongation saturated fatty acid GO:0019367 1 0.014
cell growth GO:0016049 130 0.014
negative regulation of nervous system development GO:0051961 156 0.014
oocyte construction GO:0007308 2 0.014
response to insulin GO:0032868 100 0.013
glucose homeostasis GO:0042593 128 0.013
regulation of cysteine type endopeptidase activity GO:2000116 65 0.013
gland development GO:0048732 330 0.013
regulation of interleukin 1 alpha production GO:0032650 4 0.013
epithelial cell development GO:0002064 159 0.013
regulation of interleukin 8 secretion GO:2000482 2 0.013
mitochondrion organization GO:0007005 134 0.013
response to osmotic stress GO:0006970 21 0.013
digestive tract development GO:0048565 190 0.013
neuron death GO:0070997 154 0.013
regulation of cytoplasmic transport GO:1903649 112 0.013
positive regulation of peptide hormone secretion GO:0090277 31 0.013
nuclear import GO:0051170 95 0.013
positive regulation of immune effector process GO:0002699 107 0.013
negative regulation of t cell differentiation GO:0045581 23 0.013
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.013
rhythmic process GO:0048511 174 0.013
negative regulation of secretion by cell GO:1903531 54 0.013
tissue remodeling GO:0048771 102 0.013
epithelial tube formation GO:0072175 130 0.013
microtubule based process GO:0007017 236 0.013
regulation of cell division GO:0051302 76 0.013
interferon gamma production GO:0032609 67 0.013
b cell proliferation GO:0042100 53 0.013

Sptlc2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.045
disease of anatomical entity DOID:7 0 0.034
Human
nervous system disease DOID:863 0 0.034
Human
disease of metabolism DOID:0014667 0 0.032
cancer DOID:162 0 0.030
organ system cancer DOID:0050686 0 0.030
inherited metabolic disorder DOID:655 0 0.027
musculoskeletal system disease DOID:17 0 0.024
connective tissue disease DOID:65 0 0.023
bone disease DOID:0080001 0 0.016