Mus musculus

0 known processes

Nrd1

nardilysin, N-arginine dibasic convertase, NRD convertase 1

(Aliases: 2600011I06Rik,MGC25477,AI875733,NRD-C)

Nrd1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular amino acid metabolic process GO:0006520 103 0.089
purine nucleoside metabolic process GO:0042278 241 0.085
protein modification by small protein conjugation or removal GO:0070647 207 0.073
cellular ketone metabolic process GO:0042180 84 0.073
cellular amine metabolic process GO:0044106 44 0.072
nucleobase containing small molecule metabolic process GO:0055086 352 0.071
small gtpase mediated signal transduction GO:0007264 97 0.071
regulation of cellular amino acid metabolic process GO:0006521 5 0.070
regulation of cellular amine metabolic process GO:0033238 20 0.070
purine nucleotide metabolic process GO:0006163 302 0.069
purine ribonucleotide catabolic process GO:0009154 208 0.067
membrane organization GO:0061024 245 0.065
organic cyclic compound catabolic process GO:1901361 295 0.065
nucleoside phosphate metabolic process GO:0006753 338 0.062
ribonucleotide catabolic process GO:0009261 208 0.060
purine nucleoside triphosphate catabolic process GO:0009146 203 0.059
macromolecule catabolic process GO:0009057 281 0.058
cellular macromolecule catabolic process GO:0044265 206 0.056
guanosine containing compound metabolic process GO:1901068 144 0.056
cytoplasmic transport GO:0016482 234 0.055
ras protein signal transduction GO:0007265 77 0.054
nucleoside phosphate catabolic process GO:1901292 222 0.054
regulation of cellular ketone metabolic process GO:0010565 66 0.054
amine metabolic process GO:0009308 45 0.053
protein modification by small protein conjugation GO:0032446 187 0.052
purine nucleoside triphosphate metabolic process GO:0009144 226 0.052
nucleotide catabolic process GO:0009166 217 0.051
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.050
aromatic compound catabolic process GO:0019439 286 0.050
ribonucleoside triphosphate catabolic process GO:0009203 199 0.050
regulation of organelle organization GO:0033043 289 0.050
dephosphorylation GO:0016311 129 0.049
protein catabolic process GO:0030163 221 0.048
negative regulation of cellular component organization GO:0051129 194 0.046
nucleotide metabolic process GO:0009117 332 0.046
intracellular protein transport GO:0006886 204 0.045
negative regulation of molecular function GO:0044092 258 0.045
purine ribonucleoside metabolic process GO:0046128 241 0.045
nucleoside triphosphate catabolic process GO:0009143 205 0.044
dna repair GO:0006281 107 0.044
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.044
ribonucleoside triphosphate metabolic process GO:0009199 220 0.044
heterocycle catabolic process GO:0046700 280 0.043
negative regulation of protein metabolic process GO:0051248 282 0.042
gtp catabolic process GO:0006184 143 0.042
endomembrane system organization GO:0010256 147 0.042
positive regulation of cell death GO:0010942 224 0.042
purine ribonucleoside catabolic process GO:0046130 205 0.040
establishment of protein localization to membrane GO:0090150 54 0.040
organonitrogen compound catabolic process GO:1901565 264 0.040
purine ribonucleotide metabolic process GO:0009150 290 0.039
nucleoside metabolic process GO:0009116 246 0.039
cellular nitrogen compound catabolic process GO:0044270 280 0.039
purine containing compound metabolic process GO:0072521 311 0.038
purine nucleotide catabolic process GO:0006195 211 0.038
purine nucleoside catabolic process GO:0006152 205 0.038
regulation of hydrolase activity GO:0051336 246 0.037
gtp metabolic process GO:0046039 144 0.036
ribose phosphate metabolic process GO:0019693 291 0.036
purine containing compound catabolic process GO:0072523 213 0.035
carbohydrate derivative catabolic process GO:1901136 231 0.035
positive regulation of cellular amine metabolic process GO:0033240 5 0.035
organophosphate catabolic process GO:0046434 232 0.035
endocytosis GO:0006897 168 0.034
posttranscriptional regulation of gene expression GO:0010608 155 0.034
negative regulation of phosphorylation GO:0042326 166 0.034
negative regulation of cellular protein metabolic process GO:0032269 247 0.034
transmission of nerve impulse GO:0019226 76 0.034
ribonucleoside catabolic process GO:0042454 206 0.034
ribonucleotide metabolic process GO:0009259 291 0.033
ribonucleoside metabolic process GO:0009119 245 0.033
microtubule cytoskeleton organization GO:0000226 157 0.033
regulation of protein localization GO:0032880 231 0.033
nucleoside triphosphate metabolic process GO:0009141 230 0.032
cell type specific apoptotic process GO:0097285 268 0.032
regulation of kinase activity GO:0043549 249 0.032
microtubule based process GO:0007017 236 0.032
neuronal action potential GO:0019228 54 0.031
ubiquitin dependent protein catabolic process GO:0006511 129 0.031
positive regulation of apoptotic process GO:0043065 217 0.031
mapk cascade GO:0000165 281 0.031
cellular protein catabolic process GO:0044257 155 0.031
cytokine production GO:0001816 319 0.030
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.029
positive regulation of protein modification process GO:0031401 299 0.029
protein ubiquitination GO:0016567 171 0.029
nucleoside catabolic process GO:0009164 206 0.029
protein localization to organelle GO:0033365 185 0.028
positive regulation of hydrolase activity GO:0051345 148 0.028
positive regulation of growth GO:0045927 104 0.028
protein maturation GO:0051604 176 0.028
positive regulation of cellular catabolic process GO:0031331 148 0.028
regulation of intracellular transport GO:0032386 159 0.028
immune effector process GO:0002252 321 0.028
protein processing GO:0016485 163 0.027
positive regulation of protein phosphorylation GO:0001934 242 0.027
negative regulation of protein modification process GO:0031400 163 0.027
regulation of cellular catabolic process GO:0031329 242 0.027
cellular response to dna damage stimulus GO:0006974 207 0.027
regulation of establishment of protein localization GO:0070201 181 0.027
regulation of proteolysis GO:0030162 164 0.027
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.026
dna metabolic process GO:0006259 303 0.026
regulation of membrane potential GO:0042391 192 0.026
action potential GO:0001508 78 0.026
negative regulation of phosphate metabolic process GO:0045936 184 0.026
membrane fusion GO:0061025 38 0.025
positive regulation of gtp catabolic process GO:0033126 85 0.025
negative regulation of cellular amine metabolic process GO:0033239 1 0.025
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.025
nitrogen compound transport GO:0071705 271 0.025
regulation of secretion GO:0051046 274 0.025
modification dependent protein catabolic process GO:0019941 133 0.025
guanosine containing compound catabolic process GO:1901069 144 0.025
regulation of secretion by cell GO:1903530 249 0.025
apoptotic signaling pathway GO:0097190 306 0.025
multicellular organismal signaling GO:0035637 91 0.025
response to organonitrogen compound GO:0010243 246 0.024
stem cell development GO:0048864 219 0.024
regulation of cell cycle GO:0051726 281 0.024
regulation of nucleotide metabolic process GO:0006140 169 0.024
plasma membrane organization GO:0007009 90 0.024
chromatin organization GO:0006325 206 0.023
regulation of protein transport GO:0051223 163 0.023
regulation of vesicle mediated transport GO:0060627 139 0.023
regulation of ras protein signal transduction GO:0046578 114 0.023
glycosyl compound metabolic process GO:1901657 246 0.023
chromatin modification GO:0016568 187 0.023
cellular response to organonitrogen compound GO:0071417 145 0.022
forebrain development GO:0030900 302 0.022
protein localization to plasma membrane GO:0072659 57 0.022
regulation of transferase activity GO:0051338 263 0.022
cell adhesion GO:0007155 329 0.022
cellular lipid metabolic process GO:0044255 323 0.022
neuron death GO:0070997 154 0.022
protein localization to membrane GO:0072657 108 0.021
positive regulation of organelle organization GO:0010638 128 0.021
cation transport GO:0006812 399 0.021
carbohydrate metabolic process GO:0005975 230 0.021
regulation of nucleoside metabolic process GO:0009118 130 0.021
regulation of cytokine production GO:0001817 266 0.021
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.020
nuclear transport GO:0051169 139 0.020
positive regulation of programmed cell death GO:0043068 218 0.020
regulation of reactive oxygen species metabolic process GO:2000377 40 0.020
response to peptide GO:1901652 136 0.020
regulation of gtp catabolic process GO:0033124 113 0.020
multicellular organism growth GO:0035264 161 0.020
protein targeting GO:0006605 143 0.020
regulation of cell projection organization GO:0031344 206 0.020
regulation of cytoskeleton organization GO:0051493 122 0.020
regulation of anatomical structure size GO:0090066 178 0.019
positive regulation of nucleotide catabolic process GO:0030813 88 0.019
regulation of purine nucleotide catabolic process GO:0033121 122 0.019
mitotic cell cycle GO:0000278 195 0.019
maintenance of location GO:0051235 89 0.019
germ cell development GO:0007281 185 0.019
cellular protein complex assembly GO:0043623 116 0.019
glycosyl compound catabolic process GO:1901658 206 0.019
regulation of nucleotide catabolic process GO:0030811 122 0.019
regulation of cell migration GO:0030334 219 0.019
regulation of chromosome organization GO:0033044 83 0.019
protein localization to nucleus GO:0034504 121 0.018
positive regulation of nucleotide metabolic process GO:0045981 114 0.018
organelle assembly GO:0070925 177 0.018
regulation of cellular component biogenesis GO:0044087 181 0.018
negative regulation of protein phosphorylation GO:0001933 126 0.018
neuron apoptotic process GO:0051402 142 0.018
regulation of neuron differentiation GO:0045664 281 0.018
organelle fission GO:0048285 170 0.018
synaptic transmission GO:0007268 329 0.018
negative regulation of cell proliferation GO:0008285 296 0.018
regulation of chromatin organization GO:1902275 57 0.018
positive regulation of gtpase activity GO:0043547 85 0.018
nucleocytoplasmic transport GO:0006913 139 0.018
regionalization GO:0003002 337 0.018
intrinsic apoptotic signaling pathway GO:0097193 132 0.018
regulation of chromatin modification GO:1903308 57 0.017
axonogenesis GO:0007409 274 0.017
cellular component assembly involved in morphogenesis GO:0010927 139 0.017
reactive oxygen species metabolic process GO:0072593 84 0.017
organelle localization GO:0051640 179 0.017
spermatogenesis GO:0007283 284 0.017
cell division GO:0051301 120 0.017
translation GO:0006412 93 0.017
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.017
digestive tract development GO:0048565 190 0.017
negative regulation of phosphorus metabolic process GO:0010563 184 0.017
regulation of purine nucleotide metabolic process GO:1900542 169 0.017
cellular response to hormone stimulus GO:0032870 150 0.017
regulation of cellular response to stress GO:0080135 159 0.016
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.016
telencephalon development GO:0021537 186 0.016
regulation of cell motility GO:2000145 236 0.016
positive regulation of ras gtpase activity GO:0032320 65 0.016
regulation of cellular component size GO:0032535 121 0.016
leukocyte mediated immunity GO:0002443 174 0.016
regulation of intracellular protein transport GO:0033157 82 0.016
dna recombination GO:0006310 92 0.016
peptide transport GO:0015833 133 0.016
urogenital system development GO:0001655 261 0.016
cellular carbohydrate metabolic process GO:0044262 119 0.016
inflammatory response GO:0006954 244 0.016
regulation of cell adhesion GO:0030155 154 0.016
mitotic cell cycle process GO:1903047 159 0.016
male gamete generation GO:0048232 285 0.015
regulation of endocytosis GO:0030100 69 0.015
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.015
negative regulation of nervous system development GO:0051961 156 0.015
transmembrane transport GO:0055085 412 0.015
regulation of multi organism process GO:0043900 111 0.015
regulation of protein kinase activity GO:0045859 232 0.015
engulfment of apoptotic cell GO:0043652 3 0.015
peptidyl amino acid modification GO:0018193 336 0.015
amide transport GO:0042886 138 0.015
blastocyst development GO:0001824 80 0.015
exocytosis GO:0006887 121 0.015
epithelial tube morphogenesis GO:0060562 303 0.015
regulation of endopeptidase activity GO:0052548 89 0.015
negative regulation of intracellular signal transduction GO:1902532 167 0.015
blood vessel morphogenesis GO:0048514 285 0.015
regulation of ras gtpase activity GO:0032318 88 0.015
cellular homeostasis GO:0019725 240 0.015
regulation of mitotic cell cycle GO:0007346 126 0.015
negative regulation of cell development GO:0010721 169 0.015
jnk cascade GO:0007254 72 0.015
response to organic cyclic compound GO:0014070 198 0.015
histone modification GO:0016570 159 0.015
regulation of histone modification GO:0031056 56 0.014
regulation of cell cycle process GO:0010564 160 0.014
regulation of cytoplasmic transport GO:1903649 112 0.014
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.014
response to acid chemical GO:0001101 111 0.014
modification dependent macromolecule catabolic process GO:0043632 133 0.014
regulation of protein localization to nucleus GO:1900180 60 0.014
dendrite development GO:0016358 115 0.014
defense response to other organism GO:0098542 197 0.014
cellular chemical homeostasis GO:0055082 215 0.014
lateral inhibition GO:0046331 1 0.014
regulation of protein maturation GO:1903317 96 0.014
homeostasis of number of cells GO:0048872 210 0.014
ion transmembrane transport GO:0034220 361 0.014
compound eye development GO:0048749 1 0.014
covalent chromatin modification GO:0016569 163 0.014
fat cell differentiation GO:0045444 160 0.014
protein import GO:0017038 101 0.014
response to oxidative stress GO:0006979 123 0.014
cellular response to peptide GO:1901653 92 0.014
regulation of neuron death GO:1901214 134 0.014
regulation of homeostatic process GO:0032844 182 0.013
glucose homeostasis GO:0042593 128 0.013
response to light stimulus GO:0009416 135 0.013
response to growth factor GO:0070848 198 0.013
locomotory behavior GO:0007626 195 0.013
spermatid differentiation GO:0048515 115 0.013
actin cytoskeleton organization GO:0030036 220 0.013
regulation of neuron projection development GO:0010975 169 0.013
establishment of protein localization to plasma membrane GO:0090002 34 0.013
stem cell differentiation GO:0048863 268 0.013
oxidation reduction process GO:0055114 342 0.013
positive regulation of proteolysis GO:0045862 85 0.013
rho protein signal transduction GO:0007266 32 0.013
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.013
negative regulation of multi organism process GO:0043901 68 0.013
negative regulation of immune system process GO:0002683 209 0.013
sensory organ morphogenesis GO:0090596 242 0.013
positive regulation of kinase activity GO:0033674 155 0.013
response to inorganic substance GO:0010035 96 0.013
establishment of organelle localization GO:0051656 122 0.013
monocarboxylic acid metabolic process GO:0032787 191 0.013
pallium development GO:0021543 120 0.013
rna processing GO:0006396 105 0.013
protein polymerization GO:0051258 57 0.013
renal system development GO:0072001 225 0.013
reactive oxygen species biosynthetic process GO:1903409 8 0.013
regulation of apoptotic signaling pathway GO:2001233 197 0.013
regulation of cysteine type endopeptidase activity GO:2000116 65 0.013
muscle cell differentiation GO:0042692 261 0.013
wnt signaling pathway GO:0016055 188 0.013
carbohydrate homeostasis GO:0033500 128 0.013
negative regulation of synapse assembly GO:0051964 3 0.012
establishment of protein localization to organelle GO:0072594 118 0.012
regulation of translation GO:0006417 71 0.012
proteasomal protein catabolic process GO:0010498 98 0.012
regulation of actin filament based process GO:0032970 99 0.012
regulation of cell size GO:0008361 72 0.012
cation homeostasis GO:0055080 212 0.012
camera type eye development GO:0043010 266 0.012
cofactor metabolic process GO:0051186 80 0.012
regulation of neuron apoptotic process GO:0043523 122 0.012
myelination GO:0042552 74 0.012
regulation of mapk cascade GO:0043408 248 0.012
regulation of protein complex assembly GO:0043254 83 0.012
ensheathment of neurons GO:0007272 76 0.012
organelle fusion GO:0048284 28 0.012
establishment of vesicle localization GO:0051650 81 0.012
mrna metabolic process GO:0016071 84 0.012
positive regulation of transferase activity GO:0051347 167 0.012
ribonucleoside monophosphate metabolic process GO:0009161 80 0.012
cation transmembrane transport GO:0098655 266 0.012
response to peptide hormone GO:0043434 127 0.012
negative regulation of neuron death GO:1901215 98 0.012
cell fate commitment GO:0045165 210 0.012
cellular response to growth factor stimulus GO:0071363 197 0.012
regulation of protein processing GO:0070613 96 0.012
divalent inorganic cation transport GO:0072511 178 0.012
regulation of cell activation GO:0050865 289 0.012
peptidyl serine phosphorylation GO:0018105 74 0.012
microtubule based movement GO:0007018 84 0.012
cytoskeleton dependent intracellular transport GO:0030705 50 0.012
gland development GO:0048732 330 0.012
sequestering of calcium ion GO:0051208 18 0.012
protein modification by small protein removal GO:0070646 21 0.012
cellular response to insulin stimulus GO:0032869 78 0.012
golgi vesicle transport GO:0048193 30 0.012
regulation of hormone levels GO:0010817 211 0.011
striated muscle tissue development GO:0014706 293 0.011
microtubule based transport GO:0010970 50 0.011
methylation GO:0032259 134 0.011
muscle tissue development GO:0060537 308 0.011
double strand break repair GO:0006302 48 0.011
regulation of ion transport GO:0043269 215 0.011
leukocyte differentiation GO:0002521 342 0.011
positive regulation of protein kinase activity GO:0045860 144 0.011
central nervous system neuron differentiation GO:0021953 162 0.011
adult behavior GO:0030534 135 0.011
divalent metal ion transport GO:0070838 172 0.011
cellular response to peptide hormone stimulus GO:0071375 92 0.011
nuclear division GO:0000280 158 0.011
rhythmic process GO:0048511 174 0.011
regulation of t cell activation GO:0050863 170 0.011
chemotaxis GO:0006935 247 0.011
regulation of actin cytoskeleton organization GO:0032956 84 0.011
positive regulation of cell migration GO:0030335 109 0.011
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.011
positive regulation of intracellular transport GO:0032388 70 0.011
regulation of peptidase activity GO:0052547 96 0.011
atp catabolic process GO:0006200 55 0.011
cytokinetic process GO:0032506 2 0.011
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.011
spermatid development GO:0007286 108 0.011
angiogenesis GO:0001525 201 0.011
lymphocyte mediated immunity GO:0002449 139 0.011
cognition GO:0050890 149 0.011
regulation of protein catabolic process GO:0042176 108 0.011
response to extracellular stimulus GO:0009991 127 0.011
actin polymerization or depolymerization GO:0008154 54 0.011
negative regulation of organelle organization GO:0010639 90 0.011
cilium morphogenesis GO:0060271 102 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.011
t cell activation GO:0042110 289 0.011
response to insulin GO:0032868 100 0.011
interleukin 8 production GO:0032637 4 0.011
regulation of protein targeting GO:1903533 61 0.011
heart morphogenesis GO:0003007 178 0.011
positive regulation of nucleoside metabolic process GO:0045979 91 0.011
retrograde transport endosome to golgi GO:0042147 2 0.011
axon ensheathment GO:0008366 76 0.011
positive regulation of protein catabolic process GO:0045732 60 0.010
myeloid cell differentiation GO:0030099 233 0.010
gliogenesis GO:0042063 141 0.010
morphogenesis of embryonic epithelium GO:0016331 159 0.010
kidney development GO:0001822 213 0.010
digestive system development GO:0055123 200 0.010
organic hydroxy compound metabolic process GO:1901615 203 0.010
defense response to bacterium GO:0042742 119 0.010
lipid localization GO:0010876 126 0.010
adult locomotory behavior GO:0008344 91 0.010
cellular ion homeostasis GO:0006873 165 0.010
vesicle localization GO:0051648 86 0.010
protein depolymerization GO:0051261 34 0.010
sequestering of metal ion GO:0051238 19 0.010
negative regulation of apoptotic signaling pathway GO:2001234 104 0.010
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.010
synaptic vesicle localization GO:0097479 59 0.010
developmental cell growth GO:0048588 84 0.010
sulfur compound metabolic process GO:0006790 100 0.010
vesicle organization GO:0016050 60 0.010
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.010
glial cell differentiation GO:0010001 131 0.010

Nrd1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.020
disease of anatomical entity DOID:7 0 0.020
central nervous system disease DOID:331 0 0.012
musculoskeletal system disease DOID:17 0 0.011