Mus musculus

0 known processes

Med16

mediator complex subunit 16

(Aliases: Thrap5,95kDa,Trap95,A630083L04)

Med16 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein modification by small protein conjugation or removal GO:0070647 207 0.100
covalent chromatin modification GO:0016569 163 0.092
peptidyl amino acid modification GO:0018193 336 0.087
protein acylation GO:0043543 64 0.080
chromatin organization GO:0006325 206 0.068
internal protein amino acid acetylation GO:0006475 42 0.066
nuclear division GO:0000280 158 0.063
cellular macromolecule catabolic process GO:0044265 206 0.062
histone acetylation GO:0016573 41 0.058
positive regulation of neuron differentiation GO:0045666 141 0.056
regulation of anterior head development GO:2000742 2 0.052
digestive tract development GO:0048565 190 0.049
regulation of cell cycle GO:0051726 281 0.049
protein catabolic process GO:0030163 221 0.048
neural tube development GO:0021915 160 0.045
ras protein signal transduction GO:0007265 77 0.044
regulation of cellular ketone metabolic process GO:0010565 66 0.042
regulation of cellular amine metabolic process GO:0033238 20 0.041
negative regulation of molecular function GO:0044092 258 0.041
regulation of cell cycle process GO:0010564 160 0.041
regulation of neuron differentiation GO:0045664 281 0.041
negative regulation of protein metabolic process GO:0051248 282 0.040
peptidyl lysine modification GO:0018205 77 0.039
macromolecule catabolic process GO:0009057 281 0.039
establishment of melanosome localization GO:0032401 11 0.038
synapsis GO:0007129 34 0.037
negative regulation of cellular protein metabolic process GO:0032269 247 0.036
mitotic cell cycle GO:0000278 195 0.035
synaptonemal complex assembly GO:0007130 13 0.035
cellular protein catabolic process GO:0044257 155 0.034
mitotic cell cycle process GO:1903047 159 0.033
ubiquitin dependent protein catabolic process GO:0006511 129 0.033
intracellular protein transport GO:0006886 204 0.033
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.033
melanosome localization GO:0032400 12 0.032
amine metabolic process GO:0009308 45 0.032
positive regulation of neuron projection development GO:0010976 79 0.031
histone modification GO:0016570 159 0.031
regulation of organelle organization GO:0033043 289 0.031
telencephalon development GO:0021537 186 0.031
cellular ketone metabolic process GO:0042180 84 0.031
regulation of cellular amino acid metabolic process GO:0006521 5 0.030
organonitrogen compound biosynthetic process GO:1901566 192 0.030
organelle localization GO:0051640 179 0.029
antimicrobial peptide production GO:0002775 2 0.029
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.028
modification dependent protein catabolic process GO:0019941 133 0.028
heterocycle catabolic process GO:0046700 280 0.028
purine ribonucleoside metabolic process GO:0046128 241 0.028
modification dependent macromolecule catabolic process GO:0043632 133 0.027
positive regulation of protein modification process GO:0031401 299 0.027
hematopoietic progenitor cell differentiation GO:0002244 143 0.027
protein ubiquitination GO:0016567 171 0.026
histone deubiquitination GO:0016578 2 0.026
ribose phosphate metabolic process GO:0019693 291 0.026
cellular amino acid metabolic process GO:0006520 103 0.026
forebrain development GO:0030900 302 0.026
regulation of hydrolase activity GO:0051336 246 0.026
positive regulation of anterior head development GO:2000744 2 0.025
digestive system development GO:0055123 200 0.025
cellular response to dna damage stimulus GO:0006974 207 0.025
rna processing GO:0006396 105 0.025
posttranscriptional regulation of gene expression GO:0010608 155 0.024
protein localization to organelle GO:0033365 185 0.024
establishment of protein localization to organelle GO:0072594 118 0.024
locomotory behavior GO:0007626 195 0.024
endomembrane system organization GO:0010256 147 0.023
proteasomal protein catabolic process GO:0010498 98 0.023
muscle cell differentiation GO:0042692 261 0.022
anterior head development GO:0097065 2 0.022
regulation of proteolysis GO:0030162 164 0.022
synaptic transmission GO:0007268 329 0.022
axonogenesis GO:0007409 274 0.022
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.022
spermatogenesis GO:0007283 284 0.022
regulation of anatomical structure size GO:0090066 178 0.022
dna metabolic process GO:0006259 303 0.022
apoptotic signaling pathway GO:0097190 306 0.022
regulation of mitotic cell cycle GO:0007346 126 0.022
kidney development GO:0001822 213 0.022
positive regulation of organelle organization GO:0010638 128 0.022
positive regulation of programmed cell death GO:0043068 218 0.021
body morphogenesis GO:0010171 45 0.021
regulation of cellular catabolic process GO:0031329 242 0.021
regulation of mitotic cell cycle phase transition GO:1901990 73 0.021
intrinsic apoptotic signaling pathway GO:0097193 132 0.021
positive regulation of cell development GO:0010720 237 0.021
glycosyl compound metabolic process GO:1901657 246 0.021
organophosphate biosynthetic process GO:0090407 122 0.021
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.021
regulation of protein maturation GO:1903317 96 0.020
organelle fission GO:0048285 170 0.020
cellular nitrogen compound catabolic process GO:0044270 280 0.020
male gamete generation GO:0048232 285 0.020
negative regulation of cell proliferation GO:0008285 296 0.020
positive regulation of cell projection organization GO:0031346 95 0.020
internal peptidyl lysine acetylation GO:0018393 42 0.020
peptidyl lysine acetylation GO:0018394 45 0.020
positive regulation of apoptotic process GO:0043065 217 0.020
antimicrobial peptide biosynthetic process GO:0002777 2 0.020
immune effector process GO:0002252 321 0.020
meiosis i GO:0007127 60 0.019
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.019
nucleoside triphosphate metabolic process GO:0009141 230 0.019
positive regulation of apoptotic signaling pathway GO:2001235 95 0.019
protein processing GO:0016485 163 0.019
rho protein signal transduction GO:0007266 32 0.019
establishment of organelle localization GO:0051656 122 0.019
response to light stimulus GO:0009416 135 0.019
striated muscle tissue development GO:0014706 293 0.019
microtubule based process GO:0007017 236 0.019
meiotic cell cycle GO:0051321 122 0.019
blood circulation GO:0008015 195 0.019
protein modification by small protein conjugation GO:0032446 187 0.018
cell substrate adhesion GO:0031589 130 0.018
regulation of apoptotic signaling pathway GO:2001233 197 0.018
lipid biosynthetic process GO:0008610 179 0.018
protein targeting GO:0006605 143 0.018
purine containing compound metabolic process GO:0072521 311 0.018
positive regulation of cellular amine metabolic process GO:0033240 5 0.018
positive regulation of cell cycle process GO:0090068 61 0.018
myotube cell development GO:0014904 60 0.018
negative regulation of protein modification process GO:0031400 163 0.017
vesicle localization GO:0051648 86 0.017
nucleobase containing small molecule metabolic process GO:0055086 352 0.017
regionalization GO:0003002 337 0.017
dendrite development GO:0016358 115 0.017
regulation of cell motility GO:2000145 236 0.017
regulation of transferase activity GO:0051338 263 0.017
establishment of pigment granule localization GO:0051905 12 0.017
oxidation reduction process GO:0055114 342 0.017
nucleoside phosphate metabolic process GO:0006753 338 0.017
purine nucleoside catabolic process GO:0006152 205 0.017
skeletal muscle organ development GO:0060538 163 0.017
purine nucleoside triphosphate metabolic process GO:0009144 226 0.017
mrna splicing via spliceosome GO:0000398 43 0.017
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.016
dna repair GO:0006281 107 0.016
gonad development GO:0008406 141 0.016
protein maturation GO:0051604 176 0.016
negative regulation of cell cycle GO:0045786 123 0.016
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.016
regulation of transcription by chromatin organization GO:0034401 0 0.016
cell adhesion GO:0007155 329 0.016
regulation of nucleotide metabolic process GO:0006140 169 0.016
head morphogenesis GO:0060323 34 0.016
nucleoside phosphate catabolic process GO:1901292 222 0.016
regulation of defense response GO:0031347 233 0.016
mitochondrion organization GO:0007005 134 0.015
epithelial cell development GO:0002064 159 0.015
renal system development GO:0072001 225 0.015
fertilization GO:0009566 127 0.015
muscle tissue development GO:0060537 308 0.015
cytoplasmic transport GO:0016482 234 0.015
skeletal system development GO:0001501 356 0.015
hindbrain development GO:0030902 128 0.015
regulation of antimicrobial peptide production GO:0002784 1 0.015
organonitrogen compound catabolic process GO:1901565 264 0.015
regulation of protein catabolic process GO:0042176 108 0.015
small gtpase mediated signal transduction GO:0007264 97 0.015
positive regulation of cell cycle GO:0045787 92 0.015
cellular lipid metabolic process GO:0044255 323 0.015
aromatic compound catabolic process GO:0019439 286 0.015
g protein coupled receptor signaling pathway GO:0007186 243 0.015
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.015
purine nucleotide catabolic process GO:0006195 211 0.015
regulation of cell projection organization GO:0031344 206 0.015
synaptonemal complex organization GO:0070193 15 0.014
digestive tract morphogenesis GO:0048546 147 0.014
purine nucleoside metabolic process GO:0042278 241 0.014
chromatin modification GO:0016568 187 0.014
regulation of leukocyte differentiation GO:1902105 159 0.014
epidermis development GO:0008544 187 0.014
ribonucleotide catabolic process GO:0009261 208 0.014
response to organonitrogen compound GO:0010243 246 0.014
dephosphorylation GO:0016311 129 0.014
lung development GO:0030324 164 0.014
rna splicing GO:0008380 54 0.014
mrna metabolic process GO:0016071 84 0.014
cellular amine metabolic process GO:0044106 44 0.014
organic cyclic compound catabolic process GO:1901361 295 0.014
regulation of endopeptidase activity GO:0052548 89 0.014
cellular response to lipid GO:0071396 145 0.014
protein localization to nucleus GO:0034504 121 0.014
cell fate commitment GO:0045165 210 0.014
response to lipopolysaccharide GO:0032496 128 0.014
protein dna complex subunit organization GO:0071824 28 0.014
retrograde transport endosome to golgi GO:0042147 2 0.014
spermatid differentiation GO:0048515 115 0.014
regulation of cellular response to stress GO:0080135 159 0.013
nucleoside metabolic process GO:0009116 246 0.013
regulation of system process GO:0044057 200 0.013
response to organic cyclic compound GO:0014070 198 0.013
phospholipid metabolic process GO:0006644 87 0.013
negative regulation of protein maturation GO:1903318 79 0.013
regulation of transposition GO:0010528 2 0.013
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.013
nitrogen compound transport GO:0071705 271 0.013
protein import into nucleus GO:0006606 95 0.013
stem cell fate specification GO:0048866 3 0.013
cellular protein complex assembly GO:0043623 116 0.013
circulatory system process GO:0003013 197 0.013
organophosphate catabolic process GO:0046434 232 0.013
ribonucleoside triphosphate metabolic process GO:0009199 220 0.013
regulation of multi organism process GO:0043900 111 0.013
nucleoside triphosphate catabolic process GO:0009143 205 0.013
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 35 0.013
mitochondrial transport GO:0006839 36 0.013
positive regulation of proteolysis GO:0045862 85 0.013
phospholipid biosynthetic process GO:0008654 36 0.013
response to molecule of bacterial origin GO:0002237 143 0.013
regulation of cell cycle phase transition GO:1901987 77 0.013
pallium development GO:0021543 120 0.013
urogenital system development GO:0001655 261 0.013
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 3 0.013
myotube differentiation GO:0014902 105 0.013
anatomical structure homeostasis GO:0060249 145 0.013
meiotic nuclear division GO:0007126 115 0.013
melanosome transport GO:0032402 11 0.013
negative regulation of cellular amine metabolic process GO:0033239 1 0.013
carbohydrate derivative biosynthetic process GO:1901137 183 0.013
purine nucleoside triphosphate catabolic process GO:0009146 203 0.013
positive regulation of cell death GO:0010942 224 0.013
regulation of feeding behavior GO:0060259 3 0.013
spermatid development GO:0007286 108 0.012
cellular pigmentation GO:0033059 20 0.012
purine ribonucleoside catabolic process GO:0046130 205 0.012
regulation of cellular component biogenesis GO:0044087 181 0.012
g1 s transition of mitotic cell cycle GO:0000082 57 0.012
negative regulation of phosphate metabolic process GO:0045936 184 0.012
negative regulation of protein phosphorylation GO:0001933 126 0.012
rna splicing via transesterification reactions GO:0000375 43 0.012
developmental growth involved in morphogenesis GO:0060560 138 0.012
ribonucleoside metabolic process GO:0009119 245 0.012
regulation of protein processing GO:0070613 96 0.012
production of molecular mediator of immune response GO:0002440 103 0.012
development of primary sexual characteristics GO:0045137 143 0.012
methylation GO:0032259 134 0.012
histone h4 k12 acetylation GO:0043983 2 0.012
response to transforming growth factor beta GO:0071559 88 0.012
wound healing GO:0042060 157 0.012
nucleoside catabolic process GO:0009164 206 0.012
tubulin deacetylation GO:0090042 4 0.012
apoptotic mitochondrial changes GO:0008637 48 0.012
metencephalon development GO:0022037 89 0.012
regulation of ras protein signal transduction GO:0046578 114 0.012
respiratory tube development GO:0030323 167 0.012
regulation of chromatin modification GO:1903308 57 0.012
positive regulation of protein kinase activity GO:0045860 144 0.012
multicellular organismal homeostasis GO:0048871 164 0.012
cellular amide metabolic process GO:0043603 58 0.012
nucleotide metabolic process GO:0009117 332 0.012
amide transport GO:0042886 138 0.012
carbohydrate derivative catabolic process GO:1901136 231 0.012
positive regulation of nervous system development GO:0051962 221 0.012
midbrain hindbrain boundary development GO:0030917 9 0.012
pigment granule transport GO:0051904 12 0.011
negative regulation of kinase activity GO:0033673 81 0.011
neural tube patterning GO:0021532 43 0.011
negative regulation of dna replication GO:0008156 4 0.011
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.011
ribonucleoside triphosphate catabolic process GO:0009203 199 0.011
muscle system process GO:0003012 141 0.011
fat cell differentiation GO:0045444 160 0.011
inflammatory response GO:0006954 244 0.011
ribonucleotide metabolic process GO:0009259 291 0.011
tissue homeostasis GO:0001894 115 0.011
stem cell differentiation GO:0048863 268 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.011
positive regulation of nucleotide metabolic process GO:0045981 114 0.011
negative regulation of organelle organization GO:0010639 90 0.011
connective tissue development GO:0061448 179 0.011
multicellular organism growth GO:0035264 161 0.011
skin development GO:0043588 220 0.011
purine ribonucleotide metabolic process GO:0009150 290 0.011
heart contraction GO:0060047 93 0.011
establishment of vesicle localization GO:0051650 81 0.011
negative regulation of phosphorylation GO:0042326 166 0.011
histone h3 acetylation GO:0043966 14 0.011
gtp metabolic process GO:0046039 144 0.011
regulation of antimicrobial humoral response GO:0002759 3 0.011
camera type eye development GO:0043010 266 0.011
negative regulation of protein processing GO:0010955 79 0.011
protein import GO:0017038 101 0.011
retina development in camera type eye GO:0060041 119 0.011
negative regulation of transferase activity GO:0051348 85 0.011
gastrulation GO:0007369 116 0.011
regulation of nucleotide catabolic process GO:0030811 122 0.011
phosphatidic acid biosynthetic process GO:0006654 2 0.011
regulation of chromatin organization GO:1902275 57 0.010
purine ribonucleotide catabolic process GO:0009154 208 0.010
asymmetric stem cell division GO:0098722 3 0.010
regulation of lymphocyte activation GO:0051249 240 0.010
maintenance of location GO:0051235 89 0.010
mitotic nuclear division GO:0007067 48 0.010
positive regulation of transferase activity GO:0051347 167 0.010
regulation of myeloid cell differentiation GO:0045637 96 0.010
regulation of rho protein signal transduction GO:0035023 71 0.010
regulation of neuron projection development GO:0010975 169 0.010
regulation of cytokine production GO:0001817 266 0.010
carbohydrate metabolic process GO:0005975 230 0.010
purine containing compound catabolic process GO:0072523 213 0.010
regulation of protein kinase activity GO:0045859 232 0.010
nuclear import GO:0051170 95 0.010
glycoprotein metabolic process GO:0009100 116 0.010

Med16 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.036
nervous system disease DOID:863 0 0.036
neuropathy DOID:870 0 0.018
neuromuscular disease DOID:440 0 0.016
cancer DOID:162 0 0.015
disease of cellular proliferation DOID:14566 0 0.015
sensory system disease DOID:0050155 0 0.013
organ system cancer DOID:0050686 0 0.012
eye and adnexa disease DOID:1492 0 0.011