Mus musculus

73 known processes

Igfbp4

insulin-like growth factor binding protein 4

(Aliases: IGFBP-4,AI875747,Deb2)

Igfbp4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular amino acid metabolic process GO:0006520 103 0.250
peptidyl amino acid modification GO:0018193 336 0.244
skeletal system development GO:0001501 356 0.224
regulation of cell migration GO:0030334 219 0.219
regulation of ossification GO:0030278 112 0.166
Mouse
gland development GO:0048732 330 0.154
Mouse
blood vessel morphogenesis GO:0048514 285 0.153
defense response to other organism GO:0098542 197 0.142
regulation of cellular amino acid metabolic process GO:0006521 5 0.136
mapk cascade GO:0000165 281 0.123
epithelial tube morphogenesis GO:0060562 303 0.118
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.117
regionalization GO:0003002 337 0.114
nucleoside phosphate metabolic process GO:0006753 338 0.106
negative regulation of cell proliferation GO:0008285 296 0.104
regulation of cellular response to stress GO:0080135 159 0.104
endocrine process GO:0050886 39 0.101
regulation of apoptotic signaling pathway GO:2001233 197 0.100
extracellular structure organization GO:0043062 148 0.100
actin cytoskeleton organization GO:0030036 220 0.097
negative regulation of protein metabolic process GO:0051248 282 0.096
hexose metabolic process GO:0019318 98 0.096
appendage morphogenesis GO:0035107 149 0.095
angiogenesis GO:0001525 201 0.093
embryonic organ morphogenesis GO:0048562 276 0.092
embryonic appendage morphogenesis GO:0035113 126 0.092
ossification GO:0001503 216 0.092
Mouse
aromatic compound catabolic process GO:0019439 286 0.089
nucleobase containing small molecule metabolic process GO:0055086 352 0.087
limb morphogenesis GO:0035108 149 0.087
regulation of cellular ketone metabolic process GO:0010565 66 0.087
small gtpase mediated signal transduction GO:0007264 97 0.087
nucleotide metabolic process GO:0009117 332 0.085
negative regulation of cellular protein metabolic process GO:0032269 247 0.084
peptidyl proline hydroxylation GO:0019511 3 0.084
skeletal system morphogenesis GO:0048705 203 0.083
muscle tissue development GO:0060537 308 0.081
positive regulation of cell death GO:0010942 224 0.081
amine metabolic process GO:0009308 45 0.080
carbohydrate derivative biosynthetic process GO:1901137 183 0.080
carbohydrate homeostasis GO:0033500 128 0.077
Mouse
urogenital system development GO:0001655 261 0.076
positive regulation of apoptotic process GO:0043065 217 0.074
monocarboxylic acid metabolic process GO:0032787 191 0.072
lung development GO:0030324 164 0.072
regulation of osteoblast differentiation GO:0045667 67 0.072
Mouse
glucose homeostasis GO:0042593 128 0.070
Mouse
regulation of hormone levels GO:0010817 211 0.070
respiratory tube development GO:0030323 167 0.070
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.069
apoptotic signaling pathway GO:0097190 306 0.069
regulation of response to wounding GO:1903034 189 0.069
regulation of epithelial cell proliferation GO:0050678 141 0.068
regulation of cellular amine metabolic process GO:0033238 20 0.065
positive regulation of cell motility GO:2000147 116 0.065
respiratory system development GO:0060541 190 0.065
intrinsic apoptotic signaling pathway GO:0097193 132 0.063
male gamete generation GO:0048232 285 0.061
myeloid cell differentiation GO:0030099 233 0.061
protein localization to organelle GO:0033365 185 0.061
nucleocytoplasmic transport GO:0006913 139 0.058
positive regulation of programmed cell death GO:0043068 218 0.058
positive regulation of cellular amine metabolic process GO:0033240 5 0.057
regulation of kinase activity GO:0043549 249 0.057
cellular ketone metabolic process GO:0042180 84 0.057
wnt signaling pathway GO:0016055 188 0.057
digestive tract development GO:0048565 190 0.056
positive regulation of protein kinase activity GO:0045860 144 0.055
negative regulation of intracellular signal transduction GO:1902532 167 0.055
organonitrogen compound catabolic process GO:1901565 264 0.054
regulation of anatomical structure size GO:0090066 178 0.054
cytokine production involved in immune response GO:0002367 34 0.054
liver development GO:0001889 66 0.054
stem cell maintenance GO:0019827 130 0.053
epithelial cell proliferation GO:0050673 174 0.053
regulation of hydrolase activity GO:0051336 246 0.053
palate development GO:0060021 76 0.052
germ cell development GO:0007281 185 0.052
hepaticobiliary system development GO:0061008 67 0.052
lymphocyte differentiation GO:0030098 242 0.052
limb development GO:0060173 166 0.051
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.051
cell type specific apoptotic process GO:0097285 268 0.051
heterocycle catabolic process GO:0046700 280 0.050
digestive system development GO:0055123 200 0.050
carbohydrate metabolic process GO:0005975 230 0.050
stem cell differentiation GO:0048863 268 0.050
regulation of neuron differentiation GO:0045664 281 0.050
skeletal muscle organ development GO:0060538 163 0.050
morphogenesis of a branching epithelium GO:0061138 193 0.050
axonogenesis GO:0007409 274 0.050
embryonic skeletal system development GO:0048706 120 0.049
sulfur compound metabolic process GO:0006790 100 0.049
intracellular protein transport GO:0006886 204 0.048
positive regulation of cellular catabolic process GO:0031331 148 0.048
negative regulation of epithelial cell proliferation GO:0050680 64 0.048
digestive tract morphogenesis GO:0048546 147 0.047
ear development GO:0043583 200 0.047
regulation of transferase activity GO:0051338 263 0.047
establishment of protein localization to organelle GO:0072594 118 0.047
cell junction organization GO:0034330 77 0.047
gastrulation GO:0007369 116 0.047
bone development GO:0060348 120 0.046
purine containing compound metabolic process GO:0072521 311 0.046
cell adhesion GO:0007155 329 0.046
fat cell differentiation GO:0045444 160 0.046
gliogenesis GO:0042063 141 0.045
t cell activation GO:0042110 289 0.045
regulation of mapk cascade GO:0043408 248 0.045
bmp signaling pathway GO:0030509 93 0.045
nitrogen compound transport GO:0071705 271 0.044
negative regulation of apoptotic signaling pathway GO:2001234 104 0.044
positive regulation of protein phosphorylation GO:0001934 242 0.043
protein import GO:0017038 101 0.043
spermatogenesis GO:0007283 284 0.043
protein import into nucleus GO:0006606 95 0.043
negative regulation of cell development GO:0010721 169 0.043
peptidyl tyrosine modification GO:0018212 145 0.043
protein hydroxylation GO:0018126 4 0.043
extracellular matrix organization GO:0030198 147 0.042
response to nutrient levels GO:0031667 109 0.042
cellular response to dna damage stimulus GO:0006974 207 0.042
extrinsic apoptotic signaling pathway GO:0097191 126 0.042
protein localization to nucleus GO:0034504 121 0.041
response to organic cyclic compound GO:0014070 198 0.041
embryonic limb morphogenesis GO:0030326 126 0.041
regulation of system process GO:0044057 200 0.041
regulation of fat cell differentiation GO:0045598 81 0.041
negative regulation of immune system process GO:0002683 209 0.041
regulation of secretion GO:0051046 274 0.040
cellular response to lipid GO:0071396 145 0.040
negative regulation of ossification GO:0030279 49 0.040
Mouse
wnt signaling pathway involved in somitogenesis GO:0090244 4 0.040
rhythmic process GO:0048511 174 0.040
connective tissue development GO:0061448 179 0.039
regulation of protein kinase activity GO:0045859 232 0.039
purine nucleotide metabolic process GO:0006163 302 0.039
protein targeting GO:0006605 143 0.039
regulation of proteolysis GO:0030162 164 0.039
cellular amine metabolic process GO:0044106 44 0.038
regulation of organelle organization GO:0033043 289 0.038
cellular homeostasis GO:0019725 240 0.038
lung alveolus development GO:0048286 45 0.038
ribonucleoside metabolic process GO:0009119 245 0.037
cellular response to organonitrogen compound GO:0071417 145 0.037
regulation of cytoplasmic transport GO:1903649 112 0.037
innate immune response GO:0045087 157 0.037
cellular response to hormone stimulus GO:0032870 150 0.037
vitamin metabolic process GO:0006766 23 0.037
muscle cell development GO:0055001 133 0.037
response to organonitrogen compound GO:0010243 246 0.037
negative regulation of molecular function GO:0044092 258 0.037
formation of radial glial scaffolds GO:0021943 4 0.036
negative regulation of planar cell polarity pathway involved in pericardium morphogenesis GO:2000166 1 0.036
regulation of ras protein signal transduction GO:0046578 114 0.036
glycosyl compound catabolic process GO:1901658 206 0.036
cellular chemical homeostasis GO:0055082 215 0.036
cardiac chamber morphogenesis GO:0003206 93 0.036
posttranscriptional regulation of gene expression GO:0010608 155 0.036
nucleotide catabolic process GO:0009166 217 0.036
renal system development GO:0072001 225 0.036
regulation of nucleotide metabolic process GO:0006140 169 0.035
heart morphogenesis GO:0003007 178 0.035
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.034
nucleoside triphosphate metabolic process GO:0009141 230 0.034
cartilage development GO:0051216 140 0.034
regulation of cellular component size GO:0032535 121 0.034
somatic stem cell maintenance GO:0035019 47 0.034
epithelial tube formation GO:0072175 130 0.034
blood circulation GO:0008015 195 0.034
striated muscle tissue development GO:0014706 293 0.034
somite development GO:0061053 81 0.034
sensory organ morphogenesis GO:0090596 242 0.033
amide transport GO:0042886 138 0.033
positive regulation of protein modification process GO:0031401 299 0.033
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.033
negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis GO:2000149 1 0.033
nuclear transport GO:0051169 139 0.033
positive regulation of kinase activity GO:0033674 155 0.033
glycoprotein metabolic process GO:0009100 116 0.033
purine ribonucleoside metabolic process GO:0046128 241 0.033
oxidation reduction process GO:0055114 342 0.032
regulation of cell motility GO:2000145 236 0.032
regulation of tube size GO:0035150 57 0.032
cell substrate adhesion GO:0031589 130 0.032
muscle system process GO:0003012 141 0.032
regulation of chemotaxis GO:0050920 53 0.032
purine ribonucleotide metabolic process GO:0009150 290 0.032
cytokine production GO:0001816 319 0.031
peptidyl tyrosine phosphorylation GO:0018108 143 0.031
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.031
purine nucleoside metabolic process GO:0042278 241 0.031
positive regulation of cell migration GO:0030335 109 0.031
leukocyte differentiation GO:0002521 342 0.031
organophosphate catabolic process GO:0046434 232 0.031
regulation of defense response GO:0031347 233 0.031
regulation of intracellular protein transport GO:0033157 82 0.031
regulation of endopeptidase activity GO:0052548 89 0.031
organic cyclic compound catabolic process GO:1901361 295 0.030
ameboidal type cell migration GO:0001667 128 0.030
morphogenesis of a branching structure GO:0001763 203 0.030
regulation of organ morphogenesis GO:2000027 144 0.030
neuronal action potential GO:0019228 54 0.030
odontogenesis of dentin containing tooth GO:0042475 66 0.030
embryonic skeletal system morphogenesis GO:0048704 91 0.030
neural tube development GO:0021915 160 0.030
negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis GO:2000162 1 0.030
small molecule biosynthetic process GO:0044283 132 0.030
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.030
purine nucleoside catabolic process GO:0006152 205 0.030
cellular response to cytokine stimulus GO:0071345 189 0.030
nucleoside catabolic process GO:0009164 206 0.030
response to molecule of bacterial origin GO:0002237 143 0.030
purine ribonucleotide catabolic process GO:0009154 208 0.030
nucleoside phosphate catabolic process GO:1901292 222 0.029
homeostasis of number of cells GO:0048872 210 0.029
transmembrane transport GO:0055085 412 0.029
regulation of cell projection organization GO:0031344 206 0.029
substrate adhesion dependent cell spreading GO:0034446 30 0.029
negative regulation of phosphorus metabolic process GO:0010563 184 0.029
developmental growth involved in morphogenesis GO:0060560 138 0.029
negative regulation of cellular component organization GO:0051129 194 0.029
cognition GO:0050890 149 0.029
cellular nitrogen compound catabolic process GO:0044270 280 0.029
regulation of peptidase activity GO:0052547 96 0.028
skin development GO:0043588 220 0.028
Mouse
negative regulation of protein modification process GO:0031400 163 0.028
primary neural tube formation GO:0014020 95 0.028
stem cell development GO:0048864 219 0.028
mesonephros development GO:0001823 97 0.028
regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis GO:2000150 1 0.028
tissue remodeling GO:0048771 102 0.028
Mouse
cytoplasmic transport GO:0016482 234 0.028
muscle cell differentiation GO:0042692 261 0.028
Mouse
purine containing compound catabolic process GO:0072523 213 0.028
positive regulation of nervous system development GO:0051962 221 0.028
endocytosis GO:0006897 168 0.027
regulation of planar cell polarity pathway involved in ventricular septum morphogenesis GO:2000148 1 0.027
regulation of homeostatic process GO:0032844 182 0.027
regulation of cell adhesion GO:0030155 154 0.027
inflammatory response GO:0006954 244 0.027
Rat
neural precursor cell proliferation GO:0061351 121 0.027
regulation of leukocyte differentiation GO:1902105 159 0.027
response to acid chemical GO:0001101 111 0.027
positive regulation of nucleotide metabolic process GO:0045981 114 0.027
epithelial cell development GO:0002064 159 0.027
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.027
positive regulation of protein kinase b signaling GO:0051897 32 0.027
Mouse
regulation of protein targeting GO:1903533 61 0.027
stress activated protein kinase signaling cascade GO:0031098 81 0.026
membrane organization GO:0061024 245 0.026
glycosyl compound metabolic process GO:1901657 246 0.026
glycerolipid metabolic process GO:0046486 122 0.026
cellular response to monosaccharide stimulus GO:0071326 47 0.026
forebrain development GO:0030900 302 0.026
immune effector process GO:0002252 321 0.026
somitogenesis GO:0001756 69 0.026
negative regulation of neuron differentiation GO:0045665 101 0.026
metencephalon development GO:0022037 89 0.026
activation of immune response GO:0002253 138 0.026
regulation of cytokine production GO:0001817 266 0.026
protein modification by small protein conjugation or removal GO:0070647 207 0.026
negative regulation of protein phosphorylation GO:0001933 126 0.026
organonitrogen compound biosynthetic process GO:1901566 192 0.025
actomyosin structure organization GO:0031032 56 0.025
kidney development GO:0001822 213 0.025
kidney epithelium development GO:0072073 121 0.025
defense response to bacterium GO:0042742 119 0.025
regulation of blood pressure GO:0008217 93 0.025
regulation of lymphocyte activation GO:0051249 240 0.025
cardiac septum development GO:0003279 59 0.025
positive regulation of cell development GO:0010720 237 0.025
canonical wnt signaling pathway GO:0060070 130 0.025
protein maturation GO:0051604 176 0.025
fat soluble vitamin biosynthetic process GO:0042362 4 0.025
hormone metabolic process GO:0042445 86 0.025
nuclear import GO:0051170 95 0.024
positive regulation of innate immune response GO:0045089 80 0.024
regulation of purine nucleotide metabolic process GO:1900542 169 0.024
development of primary sexual characteristics GO:0045137 143 0.024
regulation of planar cell polarity pathway involved in outflow tract morphogenesis GO:2000163 1 0.024
response to steroid hormone GO:0048545 56 0.024
planar cell polarity pathway involved in heart morphogenesis GO:0061346 3 0.024
myeloid leukocyte differentiation GO:0002573 119 0.024
cell junction assembly GO:0034329 52 0.024
regulation of vasculature development GO:1901342 88 0.024
mesenchymal cell differentiation GO:0048762 107 0.024
beta amyloid clearance GO:0097242 2 0.024
protein modification by small protein conjugation GO:0032446 187 0.024
prostate gland development GO:0030850 48 0.024
nephron development GO:0072006 109 0.023
myeloid cell homeostasis GO:0002262 114 0.023
regulation of protein import into nucleus GO:0042306 52 0.023
regulation of actin filament based process GO:0032970 99 0.023
cardiocyte differentiation GO:0035051 87 0.023
morphogenesis of embryonic epithelium GO:0016331 159 0.023
negative regulation of neuron projection regeneration GO:0070571 3 0.023
cofactor metabolic process GO:0051186 80 0.023
regulation of removal of superoxide radicals GO:2000121 4 0.023
response to inorganic substance GO:0010035 96 0.023
cardiac chamber development GO:0003205 108 0.023
ribonucleoside triphosphate catabolic process GO:0009203 199 0.023
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.023
protein glycosylation GO:0006486 55 0.023
organophosphate biosynthetic process GO:0090407 122 0.023
synapse organization GO:0050808 125 0.023
embryonic heart tube development GO:0035050 65 0.022
chemotaxis GO:0006935 247 0.022
cellular modified amino acid metabolic process GO:0006575 63 0.022
monosaccharide metabolic process GO:0005996 106 0.022
gtp catabolic process GO:0006184 143 0.022
endothelial cell apoptotic process GO:0072577 9 0.022
transmission of nerve impulse GO:0019226 76 0.022
muscle contraction GO:0006936 101 0.022
regulation of angiogenesis GO:0045765 81 0.022
negative regulation of bmp signaling pathway GO:0030514 35 0.022
single organism nuclear import GO:1902593 95 0.022
ribose phosphate metabolic process GO:0019693 291 0.022
mesenchyme development GO:0060485 152 0.022
synaptic transmission GO:0007268 329 0.022
ribonucleotide metabolic process GO:0009259 291 0.022
metal ion homeostasis GO:0055065 189 0.021
regulation of establishment of protein localization GO:0070201 181 0.021
determination of heart left right asymmetry GO:0061371 48 0.021
positive regulation of insulin receptor signaling pathway GO:0046628 4 0.021
glycoprotein biosynthetic process GO:0009101 89 0.021
diencephalon development GO:0021536 63 0.021
biomineral tissue development GO:0031214 64 0.021
purine nucleoside triphosphate metabolic process GO:0009144 226 0.021
positive regulation of mapk cascade GO:0043410 170 0.021
modification dependent protein catabolic process GO:0019941 133 0.021
regulation of phospholipase a2 activity GO:0032429 3 0.021
negative regulation of proteolysis GO:0045861 74 0.021
cellular response to organic cyclic compound GO:0071407 87 0.021
gonad development GO:0008406 141 0.021
negative regulation of cell morphogenesis involved in differentiation GO:0010771 48 0.020
hematopoietic stem cell migration GO:0035701 1 0.020
regulation of membrane potential GO:0042391 192 0.020
glycosylation GO:0070085 62 0.020
regulation of protein serine threonine kinase activity GO:0071900 157 0.020
neuron projection guidance GO:0097485 141 0.020
positive regulation of growth GO:0045927 104 0.020
regulation of protein localization GO:0032880 231 0.020
negative regulation of lymphocyte activation GO:0051250 91 0.020
epithelial cell morphogenesis GO:0003382 41 0.020
negative regulation of fat cell differentiation GO:0045599 36 0.020
cellular response to carbohydrate stimulus GO:0071322 50 0.020
regulation of wnt signaling pathway GO:0030111 123 0.020
negative regulation of platelet derived growth factor receptor beta signaling pathway GO:2000587 2 0.020
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 26 0.020
zygotic determination of anterior posterior axis embryo GO:0007354 3 0.020
embryonic epithelial tube formation GO:0001838 130 0.019
circulatory system process GO:0003013 197 0.019
segmentation GO:0035282 93 0.019
epidermis development GO:0008544 187 0.019
Mouse
axis elongation involved in somitogenesis GO:0090245 4 0.019
lipid transport GO:0006869 98 0.019
single organism cell adhesion GO:0098602 156 0.019
neuron migration GO:0001764 122 0.019
regulation of secretion by cell GO:1903530 249 0.019
purine containing compound biosynthetic process GO:0072522 70 0.019
reactive nitrogen species metabolic process GO:2001057 0 0.019
neuron death GO:0070997 154 0.019
peptide transport GO:0015833 133 0.019
hormone secretion GO:0046879 128 0.019
myotube differentiation GO:0014902 105 0.019
carboxylic acid biosynthetic process GO:0046394 86 0.019
appendage development GO:0048736 166 0.019
telencephalon development GO:0021537 186 0.019
cardiac right atrium morphogenesis GO:0003213 3 0.019
multicellular organismal signaling GO:0035637 91 0.019
ribonucleoside triphosphate metabolic process GO:0009199 220 0.019
purine nucleoside triphosphate catabolic process GO:0009146 203 0.019
regulation of intracellular transport GO:0032386 159 0.019
guanosine containing compound metabolic process GO:1901068 144 0.019
regulation of cellular response to growth factor stimulus GO:0090287 82 0.019
positive regulation of protein catabolic process GO:0045732 60 0.018
ureteric bud development GO:0001657 94 0.018
mitochondrion organization GO:0007005 134 0.018
guanosine containing compound catabolic process GO:1901069 144 0.018
macromolecule glycosylation GO:0043413 55 0.018
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.018
cell matrix adhesion GO:0007160 68 0.018
peptide hormone secretion GO:0030072 109 0.018
purine ribonucleoside catabolic process GO:0046130 205 0.018
insulin secretion GO:0030073 89 0.018
cellular response to hexose stimulus GO:0071331 47 0.018
protein localization to membrane GO:0072657 108 0.018
wnt signaling pathway involved in forebrain neuroblast division GO:0021874 2 0.018
regulation of inflammatory response GO:0050727 147 0.018
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.018
interleukin 6 production GO:0032635 58 0.018
regulation of muscle tissue development GO:1901861 97 0.018
regeneration GO:0031099 38 0.018
one carbon metabolic process GO:0006730 1 0.018
cell fate commitment GO:0045165 210 0.018
cellular response to growth factor stimulus GO:0071363 197 0.018
regulation of reactive oxygen species metabolic process GO:2000377 40 0.018
negative regulation of cell cycle GO:0045786 123 0.018
determination of left right symmetry GO:0007368 80 0.018
regulation of cell size GO:0008361 72 0.018
mesoderm morphogenesis GO:0048332 64 0.018
cardiac septum morphogenesis GO:0060411 46 0.018
cell maturation GO:0048469 127 0.018
regulation of protein transport GO:0051223 163 0.018
regulation of lipid transport GO:0032368 36 0.018
neural tube formation GO:0001841 108 0.018
ribonucleoside catabolic process GO:0042454 206 0.018
regulation of cellular catabolic process GO:0031329 242 0.018
cardiac muscle tissue development GO:0048738 130 0.018
positive regulation of behavior GO:0048520 40 0.018
ras protein signal transduction GO:0007265 77 0.018
regulation of epithelial to mesenchymal transition GO:0010717 22 0.018
rho protein signal transduction GO:0007266 32 0.017
regulation of innate immune response GO:0045088 91 0.017
negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis GO:2000164 1 0.017
branching morphogenesis of an epithelial tube GO:0048754 159 0.017
sulfur compound biosynthetic process GO:0044272 37 0.017
positive regulation of nucleotide biosynthetic process GO:0030810 26 0.017
negative regulation of wnt signaling pathway GO:0030178 73 0.017
wound healing GO:0042060 157 0.017
spermatid development GO:0007286 108 0.017
cell proliferation involved in outflow tract morphogenesis GO:0061325 4 0.017
protein catabolic process GO:0030163 221 0.017
negative regulation of planar cell polarity pathway involved in heart morphogenesis GO:2000160 1 0.017
response to lipopolysaccharide GO:0032496 128 0.017
positive regulation of nucleocytoplasmic transport GO:0046824 30 0.017
positive regulation of protein transport GO:0051222 93 0.017
renal tubule development GO:0061326 87 0.017
cellular response to acid chemical GO:0071229 68 0.017
nephron tubule development GO:0072080 84 0.017
engulfment of apoptotic cell GO:0043652 3 0.017
regulation of nucleocytoplasmic transport GO:0046822 73 0.017
negative regulation of leukocyte differentiation GO:1902106 51 0.017
leukocyte migration GO:0050900 124 0.017
positive regulation of osteoblast differentiation GO:0045669 34 0.017
negative regulation of response to wounding GO:1903035 77 0.017
regulation of rho protein signal transduction GO:0035023 71 0.017
regulation of protein kinase b signaling GO:0051896 56 0.017
Mouse
skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration GO:0014834 3 0.017
multicellular organism growth GO:0035264 161 0.017
protein processing GO:0016485 163 0.017
establishment of planar polarity of embryonic epithelium GO:0042249 16 0.017
regulation of interleukin 6 production GO:0032675 55 0.017
nucleoside triphosphate catabolic process GO:0009143 205 0.016
type b pancreatic cell proliferation GO:0044342 10 0.016
cell cell junction organization GO:0045216 72 0.016
purine nucleotide biosynthetic process GO:0006164 65 0.016
reactive oxygen species biosynthetic process GO:1903409 8 0.016
muscle cell proliferation GO:0033002 52 0.016
triglyceride metabolic process GO:0006641 51 0.016
steroid metabolic process GO:0008202 119 0.016
detection of external stimulus GO:0009581 61 0.016
nephron morphogenesis GO:0072028 69 0.016
cell growth GO:0016049 130 0.016
regulation of binding GO:0051098 111 0.016
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.016
neural tube closure GO:0001843 90 0.016
regulation of blood vessel size GO:0050880 56 0.016
tissue migration GO:0090130 68 0.016
negative regulation of phosphorylation GO:0042326 166 0.016
negative regulation of nervous system development GO:0051961 156 0.016
regulation of vesicle mediated transport GO:0060627 139 0.016
interspecies interaction between organisms GO:0044419 83 0.016
regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis GO:2000161 1 0.016
negative regulation of peptidase activity GO:0010466 46 0.016
forebrain radial glial cell differentiation GO:0021861 4 0.016
cellular carbohydrate metabolic process GO:0044262 119 0.016
camera type eye development GO:0043010 266 0.016
sterol homeostasis GO:0055092 45 0.016
ribose phosphate biosynthetic process GO:0046390 59 0.016
cation homeostasis GO:0055080 212 0.016
regulation of stem cell differentiation GO:2000736 50 0.016
positive regulation of nucleoside metabolic process GO:0045979 91 0.016
lymphocyte mediated immunity GO:0002449 139 0.015
cellular lipid metabolic process GO:0044255 323 0.015
regulation of jnk cascade GO:0046328 62 0.015
regulation of bmp signaling pathway GO:0030510 60 0.015
mitotic cell cycle process GO:1903047 159 0.015
negative regulation of endopeptidase activity GO:0010951 44 0.015
planar cell polarity pathway involved in outflow tract morphogenesis GO:0061347 2 0.015
multicellular organismal homeostasis GO:0048871 164 0.015
negative regulation of wnt signaling pathway involved in heart development GO:0003308 4 0.015
response to oxidative stress GO:0006979 123 0.015
positive regulation of protein localization to nucleus GO:1900182 30 0.015
syncytium formation by plasma membrane fusion GO:0000768 42 0.015
regulation of systemic arterial blood pressure by renin angiotensin GO:0003081 20 0.015
prostate gland morphogenesis GO:0060512 32 0.015
nucleotide sugar metabolic process GO:0009225 4 0.015
negative regulation of protein transport GO:0051224 46 0.015

Igfbp4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.247
musculoskeletal system disease DOID:17 0 0.247
connective tissue disease DOID:65 0 0.247
bone development disease DOID:0080006 0 0.104
bone disease DOID:0080001 0 0.104
disease of metabolism DOID:0014667 0 0.050
osteochondrodysplasia DOID:2256 0 0.040
inherited metabolic disorder DOID:655 0 0.031