|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.092
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.090
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.086
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.074
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
89 |
0.067
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.064
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.060
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.059
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.056
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.053
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
71 |
0.052
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.045
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.044
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.044
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.042
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.041
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
74 |
0.040
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.040
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.040
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.039
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.038
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.037
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.037
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
159 |
0.037
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.037
|
|
|
|
fibril organization
|
GO:0097435 |
2 |
0.036
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.036
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.035
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
61 |
0.034
|
|
|
|
neuronal action potential
|
GO:0019228 |
54 |
0.034
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.034
|
|
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.033
|
|
|
|
actin filament based movement
|
GO:0030048 |
23 |
0.033
|
|
|
|
blood circulation
|
GO:0008015 |
195 |
0.033
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.033
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.032
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.032
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.032
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.032
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.032
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.031
|
|
|
|
extracellular structure organization
|
GO:0043062 |
148 |
0.031
|
|
|
|
cell killing
|
GO:0001906 |
67 |
0.031
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.031
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.030
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.030
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.030
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.029
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.028
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.028
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.028
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
96 |
0.028
|
|
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.027
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
79 |
0.027
|
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.027
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.027
|
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
122 |
0.026
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.026
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
96 |
0.026
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.026
|
|
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.026
|
|
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.025
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.025
|
|
|
|
actin filament organization
|
GO:0007015 |
113 |
0.025
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
81 |
0.025
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.025
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.024
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
46 |
0.024
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.024
|
|
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.024
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.024
|
|
|
|
lung development
|
GO:0030324 |
164 |
0.024
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.024
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.024
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.023
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.023
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.023
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.023
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.023
|
|
|
|
regulation of cell growth
|
GO:0001558 |
91 |
0.023
|
|
|
|
response to uv a
|
GO:0070141 |
1 |
0.023
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.022
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.022
|
|
|
|
heart morphogenesis
|
GO:0003007 |
178 |
0.021
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.021
|
|
|
|
regulation of cell size
|
GO:0008361 |
72 |
0.021
|
|
|
|
cell growth
|
GO:0016049 |
130 |
0.021
|
|
|
|
mitochondrion organization
|
GO:0007005 |
134 |
0.021
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.021
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
159 |
0.021
|
|
|
|
lipid localization
|
GO:0010876 |
126 |
0.020
|
|
|
|
respiratory system development
|
GO:0060541 |
190 |
0.020
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.020
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.020
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.020
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.020
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
88 |
0.020
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.020
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.020
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.020
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.019
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.019
|
|
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.019
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.019
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.019
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.019
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.018
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.018
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.018
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.018
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.018
|
|
|
|
elastic fiber assembly
|
GO:0048251 |
4 |
0.018
|
|
|
|
regulation of cellular response to oxidative stress
|
GO:1900407 |
19 |
0.018
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.018
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.018
|
|
|
|
lipid transport
|
GO:0006869 |
98 |
0.018
|
|
|
|
gtp metabolic process
|
GO:0046039 |
144 |
0.018
|
|
|
|
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway
|
GO:1902176 |
4 |
0.018
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.018
|
|
|
|
protein localization to membrane
|
GO:0072657 |
108 |
0.018
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.017
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.017
|
|
|
|
tubulin complex biogenesis
|
GO:0072668 |
2 |
0.017
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.017
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.017
|
|
|
|
regulation of blood pressure
|
GO:0008217 |
93 |
0.017
|
|
|
|
appendage development
|
GO:0048736 |
166 |
0.017
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.017
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.017
|
|
|
|
embryonic limb morphogenesis
|
GO:0030326 |
126 |
0.017
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
116 |
0.016
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.016
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.016
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.016
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.016
|
|
|
|
type b pancreatic cell proliferation
|
GO:0044342 |
10 |
0.016
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.016
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.016
|
|
|
|
defense response to gram positive bacterium
|
GO:0050830 |
50 |
0.016
|
|
|
|
negative regulation of intrinsic apoptotic signaling pathway
|
GO:2001243 |
34 |
0.016
|
|
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
61 |
0.016
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.016
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.016
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
49 |
0.015
|
|
|
|
cell junction organization
|
GO:0034330 |
77 |
0.015
|
|
|
|
limb development
|
GO:0060173 |
166 |
0.015
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.015
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.015
|
|
|
|
extracellular matrix organization
|
GO:0030198 |
147 |
0.015
|
|
|
|
cardiac chamber development
|
GO:0003205 |
108 |
0.015
|
|
|
|
cilium morphogenesis
|
GO:0060271 |
102 |
0.015
|
|
|
|
actin mediated cell contraction
|
GO:0070252 |
15 |
0.015
|
|
|
|
regulation of protein processing
|
GO:0070613 |
96 |
0.015
|
|
|
|
regulation of interleukin 8 production
|
GO:0032677 |
3 |
0.014
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.014
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.014
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.014
|
|
|
|
sodium ion export
|
GO:0071436 |
2 |
0.014
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
71 |
0.014
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
87 |
0.014
|
|
|
|
intrinsic apoptotic signaling pathway in response to oxidative stress
|
GO:0008631 |
19 |
0.014
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.014
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.014
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.014
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.013
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.013
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.013
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
79 |
0.013
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
62 |
0.013
|
|
|
|
t cell mediated immunity
|
GO:0002456 |
50 |
0.013
|
|
|
|
stem cell maintenance
|
GO:0019827 |
130 |
0.013
|
|
|
|
cardiac chamber morphogenesis
|
GO:0003206 |
93 |
0.013
|
|
|
|
muscle system process
|
GO:0003012 |
141 |
0.013
|
|
|
|
negative regulation of oxidative stress induced cell death
|
GO:1903202 |
9 |
0.013
|
|
|
|
monosaccharide transport
|
GO:0015749 |
58 |
0.013
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
54 |
0.013
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.013
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.013
|
|
|
|
regulation of fat cell differentiation
|
GO:0045598 |
81 |
0.013
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.013
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
85 |
0.012
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.012
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.012
|
|
|
|
morphogenesis of a polarized epithelium
|
GO:0001738 |
37 |
0.012
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
44 |
0.012
|
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
57 |
0.012
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.012
|
|
|
|
hexose metabolic process
|
GO:0019318 |
98 |
0.012
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.012
|
|
|
|
leukocyte mediated cytotoxicity
|
GO:0001909 |
62 |
0.012
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.012
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.012
|
|
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.012
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.012
|
|
|
|
glucose transport
|
GO:0015758 |
56 |
0.012
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.012
|
|
|
|
tubulin complex assembly
|
GO:0007021 |
2 |
0.012
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.012
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.012
|
|
|
|
biomineral tissue development
|
GO:0031214 |
64 |
0.012
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
119 |
0.012
|
|
|
|
regulation of protein kinase b signaling
|
GO:0051896 |
56 |
0.012
|
|
|
|
sensory perception of mechanical stimulus
|
GO:0050954 |
107 |
0.011
|
|
|
|
response to oxidative stress
|
GO:0006979 |
123 |
0.011
|
|
|
|
embryonic appendage morphogenesis
|
GO:0035113 |
126 |
0.011
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.011
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.011
|
|
|
|
molting cycle
|
GO:0042303 |
90 |
0.011
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
70 |
0.011
|
|
|
|
regulation of transporter activity
|
GO:0032409 |
57 |
0.011
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
130 |
0.011
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.011
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
130 |
0.011
|
|
|
|
tube formation
|
GO:0035148 |
140 |
0.011
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
77 |
0.011
|
|
|
|
negative regulation of response to oxidative stress
|
GO:1902883 |
10 |
0.011
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.011
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.011
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.011
|
|
|
|
sa node cell to atrial cardiac muscle cell signalling
|
GO:0086018 |
4 |
0.011
|
|
|
|
bone development
|
GO:0060348 |
120 |
0.011
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
69 |
0.011
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.011
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.011
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.011
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
47 |
0.011
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.011
|
|
|
|
cell matrix adhesion
|
GO:0007160 |
68 |
0.011
|
|
|
|
interleukin 1 production
|
GO:0032612 |
31 |
0.011
|
|
|
|
organelle assembly
|
GO:0070925 |
177 |
0.011
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.011
|
|
|
|
protein polymerization
|
GO:0051258 |
57 |
0.011
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.011
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.011
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
81 |
0.011
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.011
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.011
|
|
|
|
response to reactive oxygen species
|
GO:0000302 |
56 |
0.010
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.010
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
72 |
0.010
|
|
|
|
positive regulation of protein kinase b signaling
|
GO:0051897 |
32 |
0.010
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.010
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.010
|
|
|
|
sodium ion export from cell
|
GO:0036376 |
1 |
0.010
|
|
|
|
positive regulation of neuron projection development
|
GO:0010976 |
79 |
0.010
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
118 |
0.010
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.010
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.010
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
138 |
0.010
|
|
|
|
extracellular fibril organization
|
GO:0043206 |
2 |
0.010
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
94 |
0.010
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.010
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.010
|
|
|
|
regulation of ossification
|
GO:0030278 |
112 |
0.010
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.010
|
|