Mus musculus

264 known processes

Ddit3

DNA-damage inducible transcript 3

(Aliases: chop,CHOP-10,gadd153,CHOP10)

Ddit3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular ketone metabolic process GO:0042180 84 0.101
cellular macromolecule catabolic process GO:0044265 206 0.089
Human
spermatogenesis GO:0007283 284 0.082
cellular amino acid metabolic process GO:0006520 103 0.074
regulation of cellular ketone metabolic process GO:0010565 66 0.072
macromolecule catabolic process GO:0009057 281 0.065
Human
cellular amine metabolic process GO:0044106 44 0.063
amine metabolic process GO:0009308 45 0.061
apoptotic signaling pathway GO:0097190 306 0.060
nucleobase containing small molecule metabolic process GO:0055086 352 0.060
regulation of transferase activity GO:0051338 263 0.058
response to endoplasmic reticulum stress GO:0034976 53 0.054
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.052
Human
modification dependent macromolecule catabolic process GO:0043632 133 0.051
Human
negative regulation of molecular function GO:0044092 258 0.051
Human Rat
regulation of cellular amine metabolic process GO:0033238 20 0.050
fat cell differentiation GO:0045444 160 0.049
carbohydrate metabolic process GO:0005975 230 0.044
muscle cell differentiation GO:0042692 261 0.043
regulation of cellular amino acid metabolic process GO:0006521 5 0.041
negative regulation of phosphorus metabolic process GO:0010563 184 0.041
dna metabolic process GO:0006259 303 0.041
modification dependent protein catabolic process GO:0019941 133 0.041
Human
mitotic cell cycle GO:0000278 195 0.040
regulation of cell cycle GO:0051726 281 0.039
response to organonitrogen compound GO:0010243 246 0.039
Rat
ubiquitin dependent protein catabolic process GO:0006511 129 0.039
Human
protein modification by small protein conjugation GO:0032446 187 0.038
regulation of kinase activity GO:0043549 249 0.038
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.038
Human
lymphocyte differentiation GO:0030098 242 0.037
negative regulation of protein metabolic process GO:0051248 282 0.037
positive regulation of protein modification process GO:0031401 299 0.037
regulation of cellular catabolic process GO:0031329 242 0.036
leukocyte differentiation GO:0002521 342 0.035
positive regulation of programmed cell death GO:0043068 218 0.033
positive regulation of apoptotic process GO:0043065 217 0.032
t cell activation GO:0042110 289 0.032
negative regulation of protein modification process GO:0031400 163 0.032
protein ubiquitination GO:0016567 171 0.032
male gamete generation GO:0048232 285 0.032
muscle tissue development GO:0060537 308 0.031
germ cell development GO:0007281 185 0.030
protein refolding GO:0042026 1 0.030
positive regulation of cellular amine metabolic process GO:0033240 5 0.030
ribonucleotide metabolic process GO:0009259 291 0.030
organic cyclic compound catabolic process GO:1901361 295 0.030
positive regulation of cell death GO:0010942 224 0.030
regulation of mapk cascade GO:0043408 248 0.030
negative regulation of cellular component organization GO:0051129 194 0.029
protein modification by small protein conjugation or removal GO:0070647 207 0.029
purine containing compound metabolic process GO:0072521 311 0.029
myeloid cell differentiation GO:0030099 233 0.029
negative regulation of phosphate metabolic process GO:0045936 184 0.028
negative regulation of kinase activity GO:0033673 81 0.028
peptidyl amino acid modification GO:0018193 336 0.028
negative regulation of cellular protein metabolic process GO:0032269 247 0.028
negative regulation of phosphorylation GO:0042326 166 0.028
cytokine production GO:0001816 319 0.027
Human
purine ribonucleotide metabolic process GO:0009150 290 0.027
regulation of protein kinase activity GO:0045859 232 0.027
regulation of binding GO:0051098 111 0.027
response to acid chemical GO:0001101 111 0.026
synaptic transmission GO:0007268 329 0.026
immune effector process GO:0002252 321 0.026
regulation of hydrolase activity GO:0051336 246 0.026
fertilization GO:0009566 127 0.026
purine nucleotide metabolic process GO:0006163 302 0.026
proteasomal protein catabolic process GO:0010498 98 0.026
Human
camera type eye development GO:0043010 266 0.026
cellular lipid metabolic process GO:0044255 323 0.026
skeletal system development GO:0001501 356 0.026
t cell differentiation GO:0030217 174 0.025
inorganic ion transmembrane transport GO:0098660 234 0.025
nucleoside phosphate metabolic process GO:0006753 338 0.024
regulation of organelle organization GO:0033043 289 0.024
regulation of cell cycle process GO:0010564 160 0.024
cell type specific apoptotic process GO:0097285 268 0.024
chromatin modification GO:0016568 187 0.024
transmembrane transport GO:0055085 412 0.023
cation transport GO:0006812 399 0.023
homeostasis of number of cells GO:0048872 210 0.023
mitotic cell cycle process GO:1903047 159 0.023
glucose metabolic process GO:0006006 92 0.023
positive regulation of protein phosphorylation GO:0001934 242 0.023
regulation of fat cell differentiation GO:0045598 81 0.023
extracellular structure organization GO:0043062 148 0.023
heterocycle catabolic process GO:0046700 280 0.022
rna processing GO:0006396 105 0.022
mapk cascade GO:0000165 281 0.022
gluconeogenesis GO:0006094 39 0.022
cellular nitrogen compound catabolic process GO:0044270 280 0.022
extracellular matrix organization GO:0030198 147 0.022
nucleotide metabolic process GO:0009117 332 0.022
myeloid cell homeostasis GO:0002262 114 0.022
ribose phosphate metabolic process GO:0019693 291 0.021
cellular protein catabolic process GO:0044257 155 0.021
Human
positive regulation of cellular catabolic process GO:0031331 148 0.021
purine ribonucleoside metabolic process GO:0046128 241 0.021
establishment of organelle localization GO:0051656 122 0.021
cellular homeostasis GO:0019725 240 0.021
response to peptide GO:1901652 136 0.021
organonitrogen compound biosynthetic process GO:1901566 192 0.021
regulation of lymphocyte activation GO:0051249 240 0.021
regulation of cellular response to stress GO:0080135 159 0.021
nucleoside triphosphate metabolic process GO:0009141 230 0.020
regulation of cellular component biogenesis GO:0044087 181 0.020
protein catabolic process GO:0030163 221 0.020
Human
protein localization to organelle GO:0033365 185 0.020
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.020
oxidation reduction process GO:0055114 342 0.020
cell adhesion GO:0007155 329 0.020
glycosyl compound metabolic process GO:1901657 246 0.020
ras protein signal transduction GO:0007265 77 0.020
small gtpase mediated signal transduction GO:0007264 97 0.019
negative regulation of transferase activity GO:0051348 85 0.019
organelle fission GO:0048285 170 0.019
negative regulation of protein phosphorylation GO:0001933 126 0.019
monosaccharide metabolic process GO:0005996 106 0.019
ribonucleoside metabolic process GO:0009119 245 0.019
nucleoside triphosphate catabolic process GO:0009143 205 0.019
organelle localization GO:0051640 179 0.019
ossification GO:0001503 216 0.019
blood vessel morphogenesis GO:0048514 285 0.019
endomembrane system organization GO:0010256 147 0.019
regulation of mitotic cell cycle GO:0007346 126 0.019
hexose biosynthetic process GO:0019319 39 0.019
cell growth GO:0016049 130 0.019
response to organic cyclic compound GO:0014070 198 0.019
regulation of protein catabolic process GO:0042176 108 0.019
translation GO:0006412 93 0.018
cellular response to organonitrogen compound GO:0071417 145 0.018
respiratory tube development GO:0030323 167 0.018
central nervous system neuron differentiation GO:0021953 162 0.018
striated muscle tissue development GO:0014706 293 0.018
regulation of transcription from rna polymerase iii promoter GO:0006359 2 0.018
nucleoside phosphate catabolic process GO:1901292 222 0.018
telencephalon development GO:0021537 186 0.018
anion transport GO:0006820 177 0.018
cation transmembrane transport GO:0098655 266 0.018
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.018
aromatic compound catabolic process GO:0019439 286 0.018
lung development GO:0030324 164 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.018
regulation of neuron differentiation GO:0045664 281 0.018
negative regulation of cell proliferation GO:0008285 296 0.017
circadian rhythm GO:0007623 114 0.017
reactive oxygen species metabolic process GO:0072593 84 0.017
regulation of leukocyte differentiation GO:1902105 159 0.017
regulation of apoptotic signaling pathway GO:2001233 197 0.017
response to insulin GO:0032868 100 0.017
p38mapk cascade GO:0038066 4 0.017
regulation of protein serine threonine kinase activity GO:0071900 157 0.017
regulation of striated muscle cell differentiation GO:0051153 81 0.017
regulation of ion transport GO:0043269 215 0.017
regulation of secretion GO:0051046 274 0.017
cellular chemical homeostasis GO:0055082 215 0.017
multicellular organism growth GO:0035264 161 0.017
regulation of cell activation GO:0050865 289 0.017
positive regulation of hydrolase activity GO:0051345 148 0.017
exocytosis GO:0006887 121 0.017
negative regulation of inclusion body assembly GO:0090084 1 0.017
sensory organ morphogenesis GO:0090596 242 0.017
ion transmembrane transport GO:0034220 361 0.017
spermatid differentiation GO:0048515 115 0.017
positive regulation of kinase activity GO:0033674 155 0.017
regulation of cytokine production GO:0001817 266 0.017
Human
transcription from rna polymerase iii promoter GO:0006383 3 0.017
muscle cell development GO:0055001 133 0.016
bone development GO:0060348 120 0.016
organelle assembly GO:0070925 177 0.016
sequestering of calcium ion GO:0051208 18 0.016
positive regulation of cellular protein catabolic process GO:1903364 34 0.016
forebrain development GO:0030900 302 0.016
regionalization GO:0003002 337 0.016
histone modification GO:0016570 159 0.016
myeloid leukocyte activation GO:0002274 83 0.016
rna splicing GO:0008380 54 0.016
regulation of reactive oxygen species metabolic process GO:2000377 40 0.016
positive regulation of proteolysis GO:0045862 85 0.016
regulation of wnt signaling pathway GO:0030111 123 0.016
inclusion body assembly GO:0070841 3 0.016
maintenance of location GO:0051235 89 0.016
ribonucleotide catabolic process GO:0009261 208 0.016
carbohydrate derivative biosynthetic process GO:1901137 183 0.016
mrna metabolic process GO:0016071 84 0.016
wound healing GO:0042060 157 0.016
endocytosis GO:0006897 168 0.016
gland development GO:0048732 330 0.016
reactive nitrogen species metabolic process GO:2001057 0 0.016
purine nucleoside metabolic process GO:0042278 241 0.016
nitrogen compound transport GO:0071705 271 0.016
response to inorganic substance GO:0010035 96 0.016
Rat
rhythmic process GO:0048511 174 0.016
compound eye development GO:0048749 1 0.015
regulation of cell projection organization GO:0031344 206 0.015
nucleotide catabolic process GO:0009166 217 0.015
lymphocyte mediated immunity GO:0002449 139 0.015
leukocyte mediated immunity GO:0002443 174 0.015
regulation of neuron death GO:1901214 134 0.015
rho protein signal transduction GO:0007266 32 0.015
monosaccharide biosynthetic process GO:0046364 44 0.015
protein maturation GO:0051604 176 0.015
positive regulation of transferase activity GO:0051347 167 0.015
response to radiation GO:0009314 165 0.015
neuron apoptotic process GO:0051402 142 0.015
anatomical structure homeostasis GO:0060249 145 0.015
microtubule based process GO:0007017 236 0.015
negative regulation of cell cycle GO:0045786 123 0.015
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.015
b cell activation GO:0042113 161 0.015
ribonucleoside triphosphate catabolic process GO:0009203 199 0.015
metal ion homeostasis GO:0055065 189 0.015
regulation of nucleotide metabolic process GO:0006140 169 0.015
purine nucleoside triphosphate catabolic process GO:0009146 203 0.015
cellular component assembly involved in morphogenesis GO:0010927 139 0.015
innate immune response GO:0045087 157 0.015
mitochondrion organization GO:0007005 134 0.015
inorganic cation transmembrane transport GO:0098662 207 0.015
nucleoside metabolic process GO:0009116 246 0.015
negative regulation of cell development GO:0010721 169 0.015
posttranscriptional regulation of gene expression GO:0010608 155 0.015
striated muscle cell development GO:0055002 125 0.015
circadian regulation of gene expression GO:0032922 48 0.014
ribonucleoside triphosphate metabolic process GO:0009199 220 0.014
gtp catabolic process GO:0006184 143 0.014
regulation of proteolysis GO:0030162 164 0.014
regulation of adaptive immune response GO:0002819 90 0.014
mitotic cytokinesis GO:0000281 4 0.014
negative regulation of cellular amine metabolic process GO:0033239 1 0.014
regulation of cell migration GO:0030334 219 0.014
organic hydroxy compound metabolic process GO:1901615 203 0.014
purine ribonucleotide catabolic process GO:0009154 208 0.014
dephosphorylation GO:0016311 129 0.014
spermatid development GO:0007286 108 0.014
negative regulation of intracellular signal transduction GO:1902532 167 0.014
regulation of body fluid levels GO:0050878 162 0.014
purine nucleotide catabolic process GO:0006195 211 0.014
positive regulation of organelle organization GO:0010638 128 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.014
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.014
cellular response to hormone stimulus GO:0032870 150 0.014
small molecule biosynthetic process GO:0044283 132 0.014
cellular protein complex assembly GO:0043623 116 0.014
regulation of myotube differentiation GO:0010830 62 0.014
regulation of secretion by cell GO:1903530 249 0.014
intracellular protein transport GO:0006886 204 0.013
organophosphate catabolic process GO:0046434 232 0.013
adaptive immune response GO:0002250 155 0.013
positive regulation of protein kinase activity GO:0045860 144 0.013
digestive system development GO:0055123 200 0.013
respiratory system development GO:0060541 190 0.013
axonogenesis GO:0007409 274 0.013
nuclear division GO:0000280 158 0.013
positive regulation of mapk cascade GO:0043410 170 0.013
peptidyl tyrosine modification GO:0018212 145 0.013
regulation of inflammatory response GO:0050727 147 0.013
regulation of neuron projection development GO:0010975 169 0.013
lipid biosynthetic process GO:0008610 179 0.013
cellular response to cytokine stimulus GO:0071345 189 0.013
response to peptide hormone GO:0043434 127 0.013
myeloid leukocyte differentiation GO:0002573 119 0.013
mrna processing GO:0006397 63 0.013
hexose metabolic process GO:0019318 98 0.013
regulation of nucleoside metabolic process GO:0009118 130 0.013
asymmetric stem cell division GO:0098722 3 0.013
regulation of neuron apoptotic process GO:0043523 122 0.013
positive regulation of cell cycle GO:0045787 92 0.013
g protein coupled receptor signaling pathway GO:0007186 243 0.013
regulation of leukocyte mediated immunity GO:0002703 104 0.013
myotube differentiation GO:0014902 105 0.013
placenta development GO:0001890 140 0.013
retina development in camera type eye GO:0060041 119 0.013
cation homeostasis GO:0055080 212 0.013
regulation of defense response GO:0031347 233 0.013
recognition of apoptotic cell GO:0043654 3 0.013
neuron death GO:0070997 154 0.013
membrane organization GO:0061024 245 0.013
carbohydrate biosynthetic process GO:0016051 74 0.013
purine containing compound catabolic process GO:0072523 213 0.013
glycosyl compound catabolic process GO:1901658 206 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.013
regulation of membrane potential GO:0042391 192 0.012
embryonic organ morphogenesis GO:0048562 276 0.012
purine nucleoside catabolic process GO:0006152 205 0.012
carbohydrate derivative catabolic process GO:1901136 231 0.012
negative regulation of immune system process GO:0002683 209 0.012
purine nucleoside triphosphate metabolic process GO:0009144 226 0.012
alpha beta t cell differentiation GO:0046632 69 0.012
regulation of chromosome organization GO:0033044 83 0.012
locomotory behavior GO:0007626 195 0.012
positive regulation of protein catabolic process GO:0045732 60 0.012
reactive oxygen species biosynthetic process GO:1903409 8 0.012
regulation of system process GO:0044057 200 0.012
nucleoside catabolic process GO:0009164 206 0.012
angiogenesis GO:0001525 201 0.012
positive regulation of lymphocyte activation GO:0051251 140 0.012
regulation of cytoskeleton organization GO:0051493 122 0.012
regulation of vesicle mediated transport GO:0060627 139 0.012
peptidyl tyrosine phosphorylation GO:0018108 143 0.012
protein folding GO:0006457 28 0.012
cell division GO:0051301 120 0.012
skeletal muscle cell differentiation GO:0035914 66 0.012
single fertilization GO:0007338 82 0.012
purine ribonucleoside catabolic process GO:0046130 205 0.012
positive regulation of binding GO:0051099 49 0.012
regulation of purine nucleotide catabolic process GO:0033121 122 0.012
protein processing GO:0016485 163 0.012
multicellular organismal homeostasis GO:0048871 164 0.012
skeletal muscle organ development GO:0060538 163 0.012
circulatory system process GO:0003013 197 0.012
organonitrogen compound catabolic process GO:1901565 264 0.012
dna repair GO:0006281 107 0.012
leukocyte activation involved in immune response GO:0002366 126 0.012
sequestering of metal ion GO:0051238 19 0.012
chromatin organization GO:0006325 206 0.012
skeletal system morphogenesis GO:0048705 203 0.012
lateral inhibition GO:0046331 1 0.011
response to molecule of bacterial origin GO:0002237 143 0.011
cell activation involved in immune response GO:0002263 126 0.011
positive regulation of cytokine production GO:0001819 174 0.011
Human
plasma membrane organization GO:0007009 90 0.011
positive regulation of t cell activation GO:0050870 101 0.011
muscle system process GO:0003012 141 0.011
microtubule cytoskeleton organization GO:0000226 157 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.011
regulation of purine nucleotide metabolic process GO:1900542 169 0.011
protein localization to membrane GO:0072657 108 0.011
regulation of nucleotide catabolic process GO:0030811 122 0.011
covalent chromatin modification GO:0016569 163 0.011
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.011
Human Rat
regulation of hormone levels GO:0010817 211 0.011
retrograde transport endosome to golgi GO:0042147 2 0.011
calcium ion transport GO:0006816 159 0.011
regulation of cell projection assembly GO:0060491 38 0.011
regulation of protein binding GO:0043393 60 0.011
regulation of protein localization GO:0032880 231 0.011
positive regulation of immune effector process GO:0002699 107 0.011
monocarboxylic acid metabolic process GO:0032787 191 0.011
response to light stimulus GO:0009416 135 0.011
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.011
wnt signaling pathway GO:0016055 188 0.011
response to lipopolysaccharide GO:0032496 128 0.011
b cell differentiation GO:0030183 78 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.011
cellular response to peptide hormone stimulus GO:0071375 92 0.011
alpha beta t cell activation GO:0046631 91 0.011
establishment of vesicle localization GO:0051650 81 0.011
ribonucleoside monophosphate metabolic process GO:0009161 80 0.011
cellular carbohydrate metabolic process GO:0044262 119 0.011
cellular ion homeostasis GO:0006873 165 0.011
hindbrain development GO:0030902 128 0.011
divalent inorganic cation transport GO:0072511 178 0.011
regulation of epithelial cell proliferation GO:0050678 141 0.011
positive regulation of nucleoside metabolic process GO:0045979 91 0.010
cellular response to insulin stimulus GO:0032869 78 0.010
developmental maturation GO:0021700 193 0.010
organophosphate biosynthetic process GO:0090407 122 0.010
actin cytoskeleton organization GO:0030036 220 0.010
regulation of anatomical structure size GO:0090066 178 0.010
negative regulation of nervous system development GO:0051961 156 0.010
response to decreased oxygen levels GO:0036293 59 0.010
renal system development GO:0072001 225 0.010
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.010
urogenital system development GO:0001655 261 0.010
lymphocyte proliferation GO:0046651 164 0.010
blood circulation GO:0008015 195 0.010
cellular response to topologically incorrect protein GO:0035967 25 0.010
cytokine metabolic process GO:0042107 71 0.010
regulation of acetylcholine secretion neurotransmission GO:0014056 2 0.010
regulation of cellular component size GO:0032535 121 0.010
leukocyte proliferation GO:0070661 172 0.010
inflammatory response GO:0006954 244 0.010
developmental growth involved in morphogenesis GO:0060560 138 0.010
synaptic vesicle transport GO:0048489 57 0.010
regulation of multi organism process GO:0043900 111 0.010
response to oxygen levels GO:0070482 62 0.010
negative regulation of proteolysis GO:0045861 74 0.010
glucose homeostasis GO:0042593 128 0.010
cellular response to peptide GO:1901653 92 0.010

Ddit3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.018
nervous system disease DOID:863 0 0.018
bone disease DOID:0080001 0 0.014
musculoskeletal system disease DOID:17 0 0.014
connective tissue disease DOID:65 0 0.014
immune system disease DOID:2914 0 0.013
central nervous system disease DOID:331 0 0.010