|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.042
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.041
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.039
|
|
|
|
cellular response to topologically incorrect protein
|
GO:0035967 |
25 |
0.037
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.037
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.035
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.034
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.033
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.033
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
143 |
0.033
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.031
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.031
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.031
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.030
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.030
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.030
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.030
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.029
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.029
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.029
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.029
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.028
|
Human |
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.028
|
|
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.027
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.027
|
|
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.027
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.026
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
116 |
0.026
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.026
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.025
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.025
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.025
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
147 |
0.025
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
130 |
0.025
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.024
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.024
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.024
|
|
|
|
regulation of protein processing
|
GO:0070613 |
96 |
0.023
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.023
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.023
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.023
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
71 |
0.023
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.022
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.022
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.022
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.022
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.022
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.022
|
|
|
|
interleukin 6 production
|
GO:0032635 |
58 |
0.021
|
|
|
|
apical constriction
|
GO:0003383 |
4 |
0.021
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.021
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
83 |
0.021
|
|
|
|
gonad development
|
GO:0008406 |
141 |
0.021
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.021
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.020
|
|
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.020
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
96 |
0.020
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.020
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.020
|
|
|
|
response to endoplasmic reticulum stress
|
GO:0034976 |
53 |
0.020
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.020
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.019
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.019
|
|
|
|
lung development
|
GO:0030324 |
164 |
0.019
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.019
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.019
|
|
|
|
actin filament polymerization
|
GO:0030041 |
44 |
0.019
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.019
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.019
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.019
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.019
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
68 |
0.019
|
|
|
|
protein targeting
|
GO:0006605 |
143 |
0.019
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.018
|
|
|
|
mitotic cytokinesis
|
GO:0000281 |
4 |
0.018
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.018
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.018
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.018
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
129 |
0.017
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
122 |
0.017
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.017
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.017
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
83 |
0.017
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.017
|
|
|
|
respiratory system development
|
GO:0060541 |
190 |
0.017
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.017
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.017
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.016
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.016
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
133 |
0.016
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.016
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
85 |
0.016
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.016
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.016
|
|
|
|
renal system development
|
GO:0072001 |
225 |
0.016
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.016
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.016
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.016
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.016
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
79 |
0.016
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.015
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.015
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.015
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.015
|
|
|
|
negative regulation of hormone metabolic process
|
GO:0032351 |
4 |
0.015
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.015
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.015
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.015
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
79 |
0.015
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.015
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.015
|
|
|
|
viral process
|
GO:0016032 |
41 |
0.015
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
84 |
0.015
|
|
|
|
response to topologically incorrect protein
|
GO:0035966 |
25 |
0.015
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.015
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.015
|
|
|
|
oocyte axis specification
|
GO:0007309 |
2 |
0.015
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.014
|
|
|
|
actin polymerization or depolymerization
|
GO:0008154 |
54 |
0.014
|
|
|
|
placenta development
|
GO:0001890 |
140 |
0.014
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.014
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.014
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.014
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.014
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.014
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.014
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
84 |
0.014
|
|
|
|
lateral inhibition
|
GO:0046331 |
1 |
0.014
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.014
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.014
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.014
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.014
|
|
|
|
appendage morphogenesis
|
GO:0035107 |
149 |
0.013
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.013
|
|
|
|
regulation of interleukin 6 production
|
GO:0032675 |
55 |
0.013
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.013
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.013
|
|
|
|
limb development
|
GO:0060173 |
166 |
0.013
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.013
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.013
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.013
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.013
|
|
|
|
response to unfolded protein
|
GO:0006986 |
21 |
0.013
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.013
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.013
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.013
|
|
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
89 |
0.013
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.013
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.013
|
|
|
|
lipid localization
|
GO:0010876 |
126 |
0.013
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.013
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.013
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.013
|
|
|
|
skeletal system morphogenesis
|
GO:0048705 |
203 |
0.013
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.013
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
89 |
0.013
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
74 |
0.013
|
|
|
|
kidney development
|
GO:0001822 |
213 |
0.013
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.013
|
|
|
|
positive regulation of interleukin 8 production
|
GO:0032757 |
2 |
0.013
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.012
|
|
|
|
chromatin organization
|
GO:0006325 |
206 |
0.012
|
|
|
|
viral transcription
|
GO:0019083 |
3 |
0.012
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.012
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.012
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.012
|
|
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
47 |
0.012
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.012
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.012
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
44 |
0.012
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
48 |
0.012
|
|
|
|
cell junction organization
|
GO:0034330 |
77 |
0.012
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.012
|
|
|
|
actin filament based movement
|
GO:0030048 |
23 |
0.012
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.012
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.012
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.012
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.012
|
|
|
|
viral gene expression
|
GO:0019080 |
3 |
0.012
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
46 |
0.012
|
|
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
85 |
0.012
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.012
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.012
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.012
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.012
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.012
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.012
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.012
|
|
|
|
regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903555 |
50 |
0.012
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.012
|
|
|
|
actin mediated cell contraction
|
GO:0070252 |
15 |
0.012
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.012
|
|
|
|
endoplasmic reticulum unfolded protein response
|
GO:0030968 |
19 |
0.012
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.012
|
|
|
|
regulation of ossification
|
GO:0030278 |
112 |
0.011
|
|
|
|
transition metal ion transport
|
GO:0000041 |
38 |
0.011
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
18 |
0.011
|
|
|
|
multi multicellular organism process
|
GO:0044706 |
109 |
0.011
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.011
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.011
|
|
|
|
fertilization
|
GO:0009566 |
127 |
0.011
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.011
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.011
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.011
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.011
|
|
|
|
keratinocyte differentiation
|
GO:0030216 |
48 |
0.011
|
|
|
|
rab protein signal transduction
|
GO:0032482 |
1 |
0.011
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.011
|
|
|
|
extracellular matrix organization
|
GO:0030198 |
147 |
0.011
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.011
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.011
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.011
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.011
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.011
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.011
|
|
|
|
cytokinetic process
|
GO:0032506 |
2 |
0.011
|
|
|
|
membrane tubulation
|
GO:0097320 |
4 |
0.011
|
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
57 |
0.011
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.011
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.011
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.011
|
|
|
|
regulation of wound healing
|
GO:0061041 |
40 |
0.011
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.010
|
|
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.010
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.010
|
|
|
|
regulation of symbiosis encompassing mutualism through parasitism
|
GO:0043903 |
52 |
0.010
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.010
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.010
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.010
|
|
|
|
regulation of viral transcription
|
GO:0046782 |
3 |
0.010
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.010
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.010
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.010
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.010
|
|
|
|
protein localization to membrane
|
GO:0072657 |
108 |
0.010
|
|
|
|
epithelial cell morphogenesis
|
GO:0003382 |
41 |
0.010
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.010
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.010
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.010
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.010
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.010
|
|