Mus musculus

4 known processes

Zdhhc8

zinc finger, DHHC domain containing 8

(Aliases: MGC7847,ZDHHCL1,MGC103030,Op53c05,E330009O14Rik,D16H22S1738E,DHHC-8,MGC118171)

Zdhhc8 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
actin cytoskeleton organization GO:0030036 220 0.114
wnt signaling pathway GO:0016055 188 0.111
small gtpase mediated signal transduction GO:0007264 97 0.109
cation transport GO:0006812 399 0.105
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.094
ras protein signal transduction GO:0007265 77 0.088
carbohydrate derivative biosynthetic process GO:1901137 183 0.081
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.079
membrane organization GO:0061024 245 0.071
nucleoside phosphate metabolic process GO:0006753 338 0.071
ion transmembrane transport GO:0034220 361 0.063
regulation of vesicle mediated transport GO:0060627 139 0.058
regulation of cellular ketone metabolic process GO:0010565 66 0.058
purine nucleotide metabolic process GO:0006163 302 0.057
stem cell differentiation GO:0048863 268 0.052
cellular amine metabolic process GO:0044106 44 0.049
regulation of cellular amino acid metabolic process GO:0006521 5 0.049
nucleobase containing small molecule metabolic process GO:0055086 352 0.048
purine containing compound metabolic process GO:0072521 311 0.047
protein modification by small protein conjugation or removal GO:0070647 207 0.045
cation transmembrane transport GO:0098655 266 0.044
rho protein signal transduction GO:0007266 32 0.044
purine ribonucleotide metabolic process GO:0009150 290 0.042
organonitrogen compound biosynthetic process GO:1901566 192 0.042
negative regulation of protein metabolic process GO:0051248 282 0.042
cellular ketone metabolic process GO:0042180 84 0.042
nucleoside metabolic process GO:0009116 246 0.041
ribose phosphate metabolic process GO:0019693 291 0.041
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.040
actin filament organization GO:0007015 113 0.040
glycoprotein metabolic process GO:0009100 116 0.039
transmembrane transport GO:0055085 412 0.039
mapk cascade GO:0000165 281 0.038
regulation of cell projection organization GO:0031344 206 0.038
amine metabolic process GO:0009308 45 0.038
regulation of cellular amine metabolic process GO:0033238 20 0.038
glycosyl compound catabolic process GO:1901658 206 0.038
lung development GO:0030324 164 0.038
rhythmic process GO:0048511 174 0.037
immune effector process GO:0002252 321 0.037
endocytosis GO:0006897 168 0.036
negative regulation of phosphorus metabolic process GO:0010563 184 0.036
response to growth factor GO:0070848 198 0.036
positive regulation of cellular amine metabolic process GO:0033240 5 0.033
chemotaxis GO:0006935 247 0.032
nucleotide metabolic process GO:0009117 332 0.032
positive regulation of protein phosphorylation GO:0001934 242 0.032
ribonucleoside metabolic process GO:0009119 245 0.032
regulation of glutamate receptor signaling pathway GO:1900449 16 0.031
stem cell development GO:0048864 219 0.030
organic cyclic compound catabolic process GO:1901361 295 0.030
negative regulation of intracellular signal transduction GO:1902532 167 0.030
regulation of cell cycle GO:0051726 281 0.030
regulation of transferase activity GO:0051338 263 0.030
regulation of mapk cascade GO:0043408 248 0.029
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.029
axonogenesis GO:0007409 274 0.029
regulation of proteolysis GO:0030162 164 0.029
regulation of actin filament based process GO:0032970 99 0.029
ribonucleoside triphosphate catabolic process GO:0009203 199 0.029
cytoplasmic transport GO:0016482 234 0.028
protein modification by small protein conjugation GO:0032446 187 0.028
regulation of membrane potential GO:0042391 192 0.028
ribonucleotide metabolic process GO:0009259 291 0.028
respiratory system development GO:0060541 190 0.028
organophosphate catabolic process GO:0046434 232 0.028
nucleoside triphosphate catabolic process GO:0009143 205 0.028
developmental growth involved in morphogenesis GO:0060560 138 0.027
leukocyte differentiation GO:0002521 342 0.027
circulatory system process GO:0003013 197 0.027
ribonucleoside triphosphate metabolic process GO:0009199 220 0.026
purine nucleoside metabolic process GO:0042278 241 0.026
cell type specific apoptotic process GO:0097285 268 0.026
inorganic cation transmembrane transport GO:0098662 207 0.026
regulation of protein kinase activity GO:0045859 232 0.025
negative regulation of cell activation GO:0050866 111 0.025
positive regulation of protein modification process GO:0031401 299 0.025
cellular response to cytokine stimulus GO:0071345 189 0.025
establishment of protein localization to organelle GO:0072594 118 0.025
vesicle organization GO:0016050 60 0.025
nucleoside triphosphate metabolic process GO:0009141 230 0.025
engulfment of apoptotic cell GO:0043652 3 0.025
regulation of establishment of protein localization GO:0070201 181 0.024
regulation of apoptotic signaling pathway GO:2001233 197 0.024
regulation of cellular component biogenesis GO:0044087 181 0.024
regulation of ion transport GO:0043269 215 0.024
heterocycle catabolic process GO:0046700 280 0.024
regulation of purine nucleotide metabolic process GO:1900542 169 0.024
positive regulation of nervous system development GO:0051962 221 0.024
organophosphate biosynthetic process GO:0090407 122 0.024
protein autophosphorylation GO:0046777 61 0.023
regionalization GO:0003002 337 0.023
jnk cascade GO:0007254 72 0.023
purine ribonucleoside metabolic process GO:0046128 241 0.023
protein localization to organelle GO:0033365 185 0.023
protein ubiquitination GO:0016567 171 0.023
peptidyl tyrosine phosphorylation GO:0018108 143 0.023
inorganic ion transmembrane transport GO:0098660 234 0.023
purine ribonucleoside catabolic process GO:0046130 205 0.023
t cell activation GO:0042110 289 0.023
microtubule based process GO:0007017 236 0.022
stress activated mapk cascade GO:0051403 80 0.022
modification dependent protein catabolic process GO:0019941 133 0.022
regulation of neuron differentiation GO:0045664 281 0.022
glycoprotein biosynthetic process GO:0009101 89 0.022
regulation of kinase activity GO:0043549 249 0.021
circadian rhythm GO:0007623 114 0.021
regulation of organelle organization GO:0033043 289 0.021
cellular response to growth factor stimulus GO:0071363 197 0.021
macromolecule catabolic process GO:0009057 281 0.021
positive regulation of cell death GO:0010942 224 0.021
positive regulation of hydrolase activity GO:0051345 148 0.021
regulation of neuron projection development GO:0010975 169 0.021
aromatic compound catabolic process GO:0019439 286 0.021
homeostasis of number of cells GO:0048872 210 0.021
carbohydrate derivative catabolic process GO:1901136 231 0.021
positive regulation of apoptotic process GO:0043065 217 0.020
respiratory tube development GO:0030323 167 0.020
single organismal cell cell adhesion GO:0016337 131 0.020
protein catabolic process GO:0030163 221 0.020
lymphocyte differentiation GO:0030098 242 0.020
guanosine containing compound metabolic process GO:1901068 144 0.020
regulation of transmembrane transport GO:0034762 128 0.020
organonitrogen compound catabolic process GO:1901565 264 0.020
protein localization to membrane GO:0072657 108 0.020
regulation of cellular catabolic process GO:0031329 242 0.020
response to radiation GO:0009314 165 0.020
blood vessel morphogenesis GO:0048514 285 0.020
nucleoside phosphate catabolic process GO:1901292 222 0.019
negative regulation of lymphocyte activation GO:0051250 91 0.019
regulation of receptor activity GO:0010469 41 0.019
purine nucleoside catabolic process GO:0006152 205 0.019
regulation of actin cytoskeleton organization GO:0032956 84 0.019
positive regulation of stress activated mapk cascade GO:0032874 48 0.019
proteoglycan biosynthetic process GO:0030166 20 0.019
regulation of ion transmembrane transport GO:0034765 119 0.019
synaptic vesicle localization GO:0097479 59 0.019
regulation of protein localization GO:0032880 231 0.018
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.018
nucleotide biosynthetic process GO:0009165 78 0.018
regulation of cell motility GO:2000145 236 0.018
canonical wnt signaling pathway GO:0060070 130 0.018
erk1 and erk2 cascade GO:0070371 77 0.018
neuron apoptotic process GO:0051402 142 0.018
regulation of cytokine production GO:0001817 266 0.018
purine nucleotide biosynthetic process GO:0006164 65 0.018
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.018
regulation of defense response GO:0031347 233 0.018
divalent inorganic cation homeostasis GO:0072507 138 0.018
inflammatory response GO:0006954 244 0.018
negative regulation of synapse assembly GO:0051964 3 0.018
regulation of map kinase activity GO:0043405 120 0.018
negative regulation of cellular protein metabolic process GO:0032269 247 0.018
regulation of stress activated mapk cascade GO:0032872 69 0.018
lipid localization GO:0010876 126 0.018
regulation of mitotic cell cycle GO:0007346 126 0.018
positive regulation of programmed cell death GO:0043068 218 0.018
positive regulation of neuron differentiation GO:0045666 141 0.018
regulation of cellular response to growth factor stimulus GO:0090287 82 0.018
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.018
stress activated protein kinase signaling cascade GO:0031098 81 0.017
positive regulation of transferase activity GO:0051347 167 0.017
negative regulation of protein modification process GO:0031400 163 0.017
regulation of jnk cascade GO:0046328 62 0.017
defecation GO:0030421 1 0.017
positive regulation of mapk cascade GO:0043410 170 0.017
positive regulation of cellular catabolic process GO:0031331 148 0.017
cell substrate adhesion GO:0031589 130 0.017
cellular homeostasis GO:0019725 240 0.017
fat cell differentiation GO:0045444 160 0.017
glycosyl compound metabolic process GO:1901657 246 0.017
intracellular protein transport GO:0006886 204 0.017
cellular lipid metabolic process GO:0044255 323 0.017
regulation of protein catabolic process GO:0042176 108 0.017
sensory perception GO:0007600 245 0.017
nucleoside phosphate biosynthetic process GO:1901293 79 0.017
male gamete generation GO:0048232 285 0.017
blood circulation GO:0008015 195 0.017
negative regulation of t cell activation GO:0050868 65 0.017
cellular chemical homeostasis GO:0055082 215 0.017
cyclic nucleotide biosynthetic process GO:0009190 44 0.017
cell chemotaxis GO:0060326 81 0.017
actin filament bundle assembly GO:0051017 40 0.017
protein palmitoylation GO:0018345 14 0.017
Human Mouse
regulation of lymphocyte activation GO:0051249 240 0.016
carbohydrate metabolic process GO:0005975 230 0.016
regulation of intracellular transport GO:0032386 159 0.016
regulation of purine nucleotide catabolic process GO:0033121 122 0.016
divalent inorganic cation transport GO:0072511 178 0.016
positive regulation of endocytosis GO:0045807 42 0.016
protein localization to plasma membrane GO:0072659 57 0.016
regulation of canonical wnt signaling pathway GO:0060828 82 0.016
muscle cell differentiation GO:0042692 261 0.016
maintenance of location GO:0051235 89 0.016
cell adhesion GO:0007155 329 0.016
protein targeting GO:0006605 143 0.016
cognition GO:0050890 149 0.016
regulation of nucleoside metabolic process GO:0009118 130 0.016
cellular nitrogen compound catabolic process GO:0044270 280 0.016
ribonucleoside catabolic process GO:0042454 206 0.016
regulation of cell activation GO:0050865 289 0.016
compound eye development GO:0048749 1 0.016
organelle localization GO:0051640 179 0.016
cellular protein catabolic process GO:0044257 155 0.015
regulation of protein serine threonine kinase activity GO:0071900 157 0.015
establishment of organelle localization GO:0051656 122 0.015
ubiquitin dependent protein catabolic process GO:0006511 129 0.015
cellular response to dna damage stimulus GO:0006974 207 0.015
multicellular organismal signaling GO:0035637 91 0.015
ribonucleotide catabolic process GO:0009261 208 0.015
mitotic cell cycle GO:0000278 195 0.015
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.015
negative regulation of immune system process GO:0002683 209 0.015
regulation of wnt signaling pathway GO:0030111 123 0.015
myeloid cell differentiation GO:0030099 233 0.015
cellular macromolecule catabolic process GO:0044265 206 0.015
regulation of circadian rhythm GO:0042752 58 0.015
metal ion homeostasis GO:0055065 189 0.015
positive regulation of cell development GO:0010720 237 0.015
regulation of jun kinase activity GO:0043506 40 0.015
regulation of gtp catabolic process GO:0033124 113 0.015
dna metabolic process GO:0006259 303 0.015
establishment of vesicle localization GO:0051650 81 0.015
cell growth GO:0016049 130 0.015
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.015
regulation of cellular response to stress GO:0080135 159 0.014
neurotransmitter secretion GO:0007269 62 0.014
muscle tissue development GO:0060537 308 0.014
g protein coupled receptor signaling pathway GO:0007186 243 0.014
regulation of nucleotide metabolic process GO:0006140 169 0.014
cytokine production GO:0001816 319 0.014
response to organonitrogen compound GO:0010243 246 0.014
negative regulation of cell proliferation GO:0008285 296 0.014
organic anion transport GO:0015711 137 0.014
negative regulation of protein phosphorylation GO:0001933 126 0.014
purine containing compound catabolic process GO:0072523 213 0.014
purine nucleotide catabolic process GO:0006195 211 0.014
regulation of secretion by cell GO:1903530 249 0.014
response to light stimulus GO:0009416 135 0.014
purine containing compound biosynthetic process GO:0072522 70 0.014
regulation of cell cycle process GO:0010564 160 0.014
purine nucleoside triphosphate metabolic process GO:0009144 226 0.014
modification dependent macromolecule catabolic process GO:0043632 133 0.014
innate immune response GO:0045087 157 0.014
regulation of homeostatic process GO:0032844 182 0.014
establishment of synaptic vesicle localization GO:0097480 57 0.014
reactive oxygen species metabolic process GO:0072593 84 0.014
cellular response to lipid GO:0071396 145 0.014
regulation of cellular protein catabolic process GO:1903362 61 0.014
asymmetric neuroblast division GO:0055059 1 0.014
regulation of protein maturation GO:1903317 96 0.014
multicellular organism growth GO:0035264 161 0.014
aminoglycan metabolic process GO:0006022 34 0.014
smoothened signaling pathway GO:0007224 105 0.014
peptidyl tyrosine modification GO:0018212 145 0.013
rap protein signal transduction GO:0032486 3 0.013
multicellular organismal homeostasis GO:0048871 164 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.013
mucopolysaccharide metabolic process GO:1903510 25 0.013
cellularization GO:0007349 1 0.013
neuron death GO:0070997 154 0.013
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.013
nucleotide catabolic process GO:0009166 217 0.013
extracellular matrix organization GO:0030198 147 0.013
meiotic cell cycle GO:0051321 122 0.013
gtp metabolic process GO:0046039 144 0.013
protein localization to nucleus GO:0034504 121 0.013
anion transport GO:0006820 177 0.013
purine nucleoside triphosphate catabolic process GO:0009146 203 0.013
peptidyl amino acid modification GO:0018193 336 0.013
positive regulation of apoptotic signaling pathway GO:2001235 95 0.013
positive regulation of kinase activity GO:0033674 155 0.013
dephosphorylation GO:0016311 129 0.013
response to lipopolysaccharide GO:0032496 128 0.013
regulation of anatomical structure size GO:0090066 178 0.013
positive regulation of nucleoside metabolic process GO:0045979 91 0.013
lateral inhibition GO:0046331 1 0.013
cation homeostasis GO:0055080 212 0.013
regulation of lipid metabolic process GO:0019216 118 0.013
anatomical structure homeostasis GO:0060249 145 0.013
regulation of t cell activation GO:0050863 170 0.013
positive regulation of cell migration GO:0030335 109 0.013
organelle fission GO:0048285 170 0.013
negative regulation of ras protein signal transduction GO:0046580 18 0.012
negative regulation of phosphate metabolic process GO:0045936 184 0.012
proteasomal protein catabolic process GO:0010498 98 0.012
extrinsic apoptotic signaling pathway GO:0097191 126 0.012
striated muscle tissue development GO:0014706 293 0.012
regulation of secretion GO:0051046 274 0.012
nuclear transport GO:0051169 139 0.012
negative regulation of molecular function GO:0044092 258 0.012
microtubule cytoskeleton organization GO:0000226 157 0.012
leukocyte homeostasis GO:0001776 79 0.012
regulation of inflammatory response GO:0050727 147 0.012
mesenchymal cell development GO:0014031 93 0.012
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.012
myotube differentiation GO:0014902 105 0.012
neurotransmitter transport GO:0006836 76 0.012
regulation of cell growth GO:0001558 91 0.012
divalent metal ion transport GO:0070838 172 0.012
cell fate commitment GO:0045165 210 0.012
forebrain development GO:0030900 302 0.012
protein maturation GO:0051604 176 0.012
positive regulation of nucleotide metabolic process GO:0045981 114 0.012
negative regulation of wnt signaling pathway GO:0030178 73 0.012
telencephalon development GO:0021537 186 0.012
regulation of erk1 and erk2 cascade GO:0070372 71 0.012
reactive oxygen species biosynthetic process GO:1903409 8 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.012
tissue migration GO:0090130 68 0.012
purine ribonucleotide biosynthetic process GO:0009152 59 0.012
protein processing GO:0016485 163 0.011
sensory perception of mechanical stimulus GO:0050954 107 0.011
gtp catabolic process GO:0006184 143 0.011
response to extracellular stimulus GO:0009991 127 0.011
cell matrix adhesion GO:0007160 68 0.011
asymmetric stem cell division GO:0098722 3 0.011
protein import GO:0017038 101 0.011
regulation of cytoplasmic transport GO:1903649 112 0.011
monosaccharide metabolic process GO:0005996 106 0.011
dna repair GO:0006281 107 0.011
cellular protein complex assembly GO:0043623 116 0.011
reactive nitrogen species metabolic process GO:2001057 0 0.011
intrinsic apoptotic signaling pathway GO:0097193 132 0.011
transmission of nerve impulse GO:0019226 76 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.011
positive regulation of cell cycle process GO:0090068 61 0.011
negative regulation of neuron differentiation GO:0045665 101 0.011
oxidation reduction process GO:0055114 342 0.011
response to transforming growth factor beta GO:0071559 88 0.011
developmental maturation GO:0021700 193 0.011
regulation of cytoskeleton organization GO:0051493 122 0.011
glycosylation GO:0070085 62 0.011
learning or memory GO:0007611 148 0.011
purine ribonucleotide catabolic process GO:0009154 208 0.011
skeletal system morphogenesis GO:0048705 203 0.011
epithelial cell migration GO:0010631 63 0.011
oocyte axis specification GO:0007309 2 0.011
sterol homeostasis GO:0055092 45 0.011
regulation of neuron death GO:1901214 134 0.011
regulation of g protein coupled receptor protein signaling pathway GO:0008277 37 0.011
positive regulation of ras gtpase activity GO:0032320 65 0.011
negative regulation of cell cycle GO:0045786 123 0.011
cellular ion homeostasis GO:0006873 165 0.011
regulation of cellular component size GO:0032535 121 0.011
stem cell maintenance GO:0019827 130 0.011
ribonucleotide biosynthetic process GO:0009260 59 0.011
nucleotide sugar metabolic process GO:0009225 4 0.011
sequestering of calcium ion GO:0051208 18 0.011
regulation of cell substrate adhesion GO:0010810 73 0.011
neuron projection guidance GO:0097485 141 0.011
epithelial cell proliferation GO:0050673 174 0.011
regulation of feeding behavior GO:0060259 3 0.011
methylation GO:0032259 134 0.011
phagocytosis GO:0006909 66 0.010
carbohydrate homeostasis GO:0033500 128 0.010
lymphocyte proliferation GO:0046651 164 0.010
regulation of protein ubiquitination GO:0031396 52 0.010
regulation of leukocyte proliferation GO:0070663 121 0.010
regulation of leukocyte differentiation GO:1902105 159 0.010
regulation of angiogenesis GO:0045765 81 0.010
regulation of protein transport GO:0051223 163 0.010
midgut development GO:0007494 4 0.010
cellular divalent inorganic cation homeostasis GO:0072503 127 0.010
ribonucleoside monophosphate metabolic process GO:0009161 80 0.010
notch signaling pathway GO:0007219 71 0.010
calcium ion transport GO:0006816 159 0.010
angiogenesis GO:0001525 201 0.010
positive regulation of cell adhesion GO:0045785 80 0.010
endothelial cell migration GO:0043542 44 0.010
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.010
regulation of endocytosis GO:0030100 69 0.010
epithelium migration GO:0090132 63 0.010
skeletal muscle organ development GO:0060538 163 0.010

Zdhhc8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.026
disease of anatomical entity DOID:7 0 0.026
musculoskeletal system disease DOID:17 0 0.016
cancer DOID:162 0 0.015
disease of cellular proliferation DOID:14566 0 0.015
connective tissue disease DOID:65 0 0.012
neuromuscular disease DOID:440 0 0.012
neuropathy DOID:870 0 0.012