Mus musculus

0 known processes

Grik4

glutamate receptor, ionotropic, kainate 4

(Aliases: 6330551K01Rik,KA1,KA-1,GluK4,GluRgamma1)

Grik4 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of excitatory postsynaptic membrane potential GO:0060079 41 0.674
Mouse
glutamate receptor signaling pathway GO:0007215 35 0.542
Mouse
membrane depolarization GO:0051899 64 0.531
Mouse
negative regulation of synaptic transmission glutamatergic GO:0051967 4 0.441
Mouse
regulation of neuronal synaptic plasticity GO:0048168 30 0.428
regulation of short term neuronal synaptic plasticity GO:0048172 8 0.389
regulation of synaptic plasticity GO:0048167 87 0.348
regulation of long term neuronal synaptic plasticity GO:0048169 19 0.314
ion transmembrane transport GO:0034220 361 0.297
Mouse
multicellular organismal response to stress GO:0033555 62 0.297
Mouse
transmembrane transport GO:0055085 412 0.283
Mouse
synaptic transmission GO:0007268 329 0.256
Mouse
long term memory GO:0007616 15 0.227
regulation of long term synaptic depression GO:1900452 3 0.215
memory GO:0007613 58 0.174
positive regulation of nervous system development GO:0051962 221 0.164
cellular homeostasis GO:0019725 240 0.160
mapk cascade GO:0000165 281 0.160
long term synaptic depression GO:0060292 13 0.151
divalent inorganic cation homeostasis GO:0072507 138 0.142
regulation of membrane potential GO:0042391 192 0.133
Mouse
membrane organization GO:0061024 245 0.120
Mouse
cation transmembrane transport GO:0098655 266 0.114
intracellular protein transport GO:0006886 204 0.106
learning or memory GO:0007611 148 0.105
metal ion homeostasis GO:0055065 189 0.098
positive regulation of cell development GO:0010720 237 0.096
kidney development GO:0001822 213 0.093
amine metabolic process GO:0009308 45 0.091
negative regulation of neuron death GO:1901215 98 0.089
cognition GO:0050890 149 0.088
regulation of ion transport GO:0043269 215 0.082
Mouse
fear response GO:0042596 33 0.079
striatal medium spiny neuron differentiation GO:0021773 2 0.079
regulation of cellular ketone metabolic process GO:0010565 66 0.078
inorganic cation transmembrane transport GO:0098662 207 0.076
small gtpase mediated signal transduction GO:0007264 97 0.075
regulation of long term synaptic potentiation GO:1900271 4 0.075
ras protein signal transduction GO:0007265 77 0.074
cellular calcium ion homeostasis GO:0006874 119 0.074
long term synaptic potentiation GO:0060291 25 0.073
divalent inorganic cation transport GO:0072511 178 0.071
g protein coupled receptor signaling pathway GO:0007186 243 0.071
cellular ion homeostasis GO:0006873 165 0.071
positive regulation of cell projection organization GO:0031346 95 0.071
cation transport GO:0006812 399 0.069
calcium ion homeostasis GO:0055074 127 0.066
regulation of mapk cascade GO:0043408 248 0.066
cellular chemical homeostasis GO:0055082 215 0.064
neuron apoptotic process GO:0051402 142 0.064
cellular metal ion homeostasis GO:0006875 151 0.062
dendritic spine organization GO:0097061 26 0.061
regulation of ion transmembrane transporter activity GO:0032412 54 0.061
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.061
regulation of cellular amino acid metabolic process GO:0006521 5 0.060
cell type specific apoptotic process GO:0097285 268 0.059
sensory perception of pain GO:0019233 47 0.058
cellular lipid metabolic process GO:0044255 323 0.058
cellular divalent inorganic cation homeostasis GO:0072503 127 0.058
axonogenesis GO:0007409 274 0.057
protein autophosphorylation GO:0046777 61 0.055
cation homeostasis GO:0055080 212 0.055
transmission of nerve impulse GO:0019226 76 0.054
calcium ion transmembrane transport GO:0070588 85 0.053
regulation of postsynaptic membrane potential GO:0060078 48 0.053
Mouse
regulation of organelle organization GO:0033043 289 0.051
Mouse
cyclic purine nucleotide metabolic process GO:0052652 43 0.049
negative regulation of nervous system development GO:0051961 156 0.049
dendritic spine development GO:0060996 30 0.048
alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor clustering GO:0097113 3 0.048
multicellular organismal signaling GO:0035637 91 0.047
negative regulation of cell proliferation GO:0008285 296 0.047
positive regulation of mapk cascade GO:0043410 170 0.047
male gamete generation GO:0048232 285 0.047
response to organonitrogen compound GO:0010243 246 0.047
amide transport GO:0042886 138 0.046
behavioral defense response GO:0002209 28 0.046
regulation of ion transmembrane transport GO:0034765 119 0.046
negative regulation of neuron apoptotic process GO:0043524 92 0.046
cellular ketone metabolic process GO:0042180 84 0.046
calcium ion transport GO:0006816 159 0.046
regulation of cell cycle GO:0051726 281 0.045
lateral inhibition GO:0046331 1 0.045
habituation GO:0046959 3 0.044
neuron death GO:0070997 154 0.044
directional locomotion GO:0033058 3 0.043
neuromuscular process controlling balance GO:0050885 59 0.043
regulation of neuron apoptotic process GO:0043523 122 0.043
inorganic ion transmembrane transport GO:0098660 234 0.042
muscle contraction GO:0006936 101 0.042
negative regulation of phosphorylation GO:0042326 166 0.041
purine ribonucleotide metabolic process GO:0009150 290 0.041
negative regulation of phosphorus metabolic process GO:0010563 184 0.041
regulation of cellular component biogenesis GO:0044087 181 0.041
dephosphorylation GO:0016311 129 0.041
regulation of neuron differentiation GO:0045664 281 0.041
regulation of cell migration GO:0030334 219 0.040
circulatory system process GO:0003013 197 0.040
positive regulation of ion transmembrane transporter activity GO:0032414 15 0.040
cytoplasmic transport GO:0016482 234 0.039
divalent metal ion transport GO:0070838 172 0.039
skeletal system development GO:0001501 356 0.038
positive regulation of membrane potential GO:0045838 15 0.038
cell adhesion GO:0007155 329 0.038
membrane hyperpolarization GO:0060081 21 0.038
Mouse
actin cytoskeleton organization GO:0030036 220 0.038
positive regulation of long term neuronal synaptic plasticity GO:0048170 3 0.037
regulation of cell cycle process GO:0010564 160 0.037
cellular amine metabolic process GO:0044106 44 0.037
apoptotic signaling pathway GO:0097190 306 0.037
response to epidermal growth factor GO:0070849 4 0.037
regulation of neuron death GO:1901214 134 0.036
carbohydrate derivative biosynthetic process GO:1901137 183 0.036
g protein coupled glutamate receptor signaling pathway GO:0007216 3 0.036
cellular response to organonitrogen compound GO:0071417 145 0.036
regulation of alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor activity GO:2000311 11 0.035
meiotic cell cycle GO:0051321 122 0.035
protein catabolic process GO:0030163 221 0.035
positive regulation of neuron projection development GO:0010976 79 0.035
cellular response to lipid GO:0071396 145 0.035
skeletal system morphogenesis GO:0048705 203 0.034
positive regulation of insulin secretion GO:0032024 26 0.034
nucleoside triphosphate metabolic process GO:0009141 230 0.034
compound eye development GO:0048749 1 0.034
stem cell fate specification GO:0048866 3 0.033
nucleoside phosphate metabolic process GO:0006753 338 0.033
positive regulation of cellular amine metabolic process GO:0033240 5 0.033
hormone secretion GO:0046879 128 0.033
conditioned taste aversion GO:0001661 4 0.032
regulation of map kinase activity GO:0043405 120 0.032
purine containing compound metabolic process GO:0072521 311 0.032
ribonucleotide metabolic process GO:0009259 291 0.031
rap protein signal transduction GO:0032486 3 0.031
regulation of cellular amine metabolic process GO:0033238 20 0.031
regulation of cell motility GO:2000145 236 0.031
regulation of anatomical structure size GO:0090066 178 0.031
germ cell development GO:0007281 185 0.031
neuronal action potential GO:0019228 54 0.031
response to molecule of bacterial origin GO:0002237 143 0.031
positive regulation of neuron differentiation GO:0045666 141 0.030
blood circulation GO:0008015 195 0.030
glial cell differentiation GO:0010001 131 0.030
positive regulation of protein modification process GO:0031401 299 0.030
regulation of ovulation GO:0060278 3 0.030
nucleoside phosphate biosynthetic process GO:1901293 79 0.029
regulation of behavioral fear response GO:2000822 2 0.029
fat cell differentiation GO:0045444 160 0.029
oocyte construction GO:0007308 2 0.029
regionalization GO:0003002 337 0.029
reactive oxygen species biosynthetic process GO:1903409 8 0.029
positive regulation of protein phosphorylation GO:0001934 242 0.029
reactive nitrogen species metabolic process GO:2001057 0 0.028
protein localization to membrane GO:0072657 108 0.028
developmental maturation GO:0021700 193 0.028
leukocyte proliferation GO:0070661 172 0.028
endocytosis GO:0006897 168 0.028
dendritic spine morphogenesis GO:0060997 22 0.028
ossification GO:0001503 216 0.028
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.028
negative regulation of mapk cascade GO:0043409 65 0.027
maintenance of location GO:0051235 89 0.027
regulation of peptide secretion GO:0002791 77 0.027
single organism cell adhesion GO:0098602 156 0.027
muscle tissue development GO:0060537 308 0.027
cell growth GO:0016049 130 0.027
regulation of homeostatic process GO:0032844 182 0.026
regulation of jnk cascade GO:0046328 62 0.026
positive regulation of organelle organization GO:0010638 128 0.026
positive regulation of cellular component biogenesis GO:0044089 94 0.026
activation of meiosis GO:0090427 4 0.026
regulation of calcium ion transport GO:0051924 69 0.026
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.026
cellular response to hormone stimulus GO:0032870 150 0.026
regulation of transferase activity GO:0051338 263 0.026
regulation of cell projection organization GO:0031344 206 0.026
negative regulation of protein metabolic process GO:0051248 282 0.026
neuron neuron synaptic transmission GO:0007270 69 0.026
Mouse
learning GO:0007612 98 0.026
olfactory learning GO:0008355 2 0.025
response to monosaccharide GO:0034284 67 0.025
myotube differentiation GO:0014902 105 0.025
reactive oxygen species metabolic process GO:0072593 84 0.025
regulation of cellular component size GO:0032535 121 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.025
defecation GO:0030421 1 0.025
single organismal cell cell adhesion GO:0016337 131 0.025
actin filament organization GO:0007015 113 0.025
urogenital system development GO:0001655 261 0.025
response to peptide GO:1901652 136 0.025
regulation of metal ion transport GO:0010959 106 0.024
zygotic determination of anterior posterior axis embryo GO:0007354 3 0.024
jnk cascade GO:0007254 72 0.024
protein maturation GO:0051604 176 0.024
behavioral fear response GO:0001662 28 0.024
sensory perception GO:0007600 245 0.024
negative regulation of cellular protein metabolic process GO:0032269 247 0.024
nucleotide metabolic process GO:0009117 332 0.023
canonical wnt signaling pathway GO:0060070 130 0.023
peptidyl tyrosine modification GO:0018212 145 0.023
cellular response to ethanol GO:0071361 3 0.023
leukocyte differentiation GO:0002521 342 0.023
positive regulation of glutamate receptor signaling pathway GO:1900451 3 0.023
regulation of proteolysis GO:0030162 164 0.023
negative regulation of synapse assembly GO:0051964 3 0.023
phospholipid metabolic process GO:0006644 87 0.023
response to lipopolysaccharide GO:0032496 128 0.023
spermatogenesis GO:0007283 284 0.023
organophosphate biosynthetic process GO:0090407 122 0.023
nuclear transport GO:0051169 139 0.023
regulation of secretion GO:0051046 274 0.023
Mouse
oocyte axis specification GO:0007309 2 0.023
regulation of dendritic spine development GO:0060998 22 0.023
cellular macromolecule catabolic process GO:0044265 206 0.022
positive regulation of excitatory postsynaptic membrane potential GO:2000463 14 0.022
purine containing compound biosynthetic process GO:0072522 70 0.022
cell cell junction organization GO:0045216 72 0.022
sequestering of calcium ion GO:0051208 18 0.022
extracellular matrix organization GO:0030198 147 0.022
negative regulation of immune system process GO:0002683 209 0.022
adherens junction organization GO:0034332 28 0.022
positive regulation of peptide hormone secretion GO:0090277 31 0.022
regulation of hormone secretion GO:0046883 88 0.022
striated muscle tissue development GO:0014706 293 0.022
insulin secretion GO:0030073 89 0.022
maintenance of apical basal cell polarity GO:0035090 3 0.021
ribonucleotide biosynthetic process GO:0009260 59 0.021
regulation of hydrolase activity GO:0051336 246 0.021
negative regulation of neuron differentiation GO:0045665 101 0.021
macromolecule catabolic process GO:0009057 281 0.021
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.021
regulation of cellular response to stress GO:0080135 159 0.021
detection of mechanical stimulus involved in sensory perception of pain GO:0050966 4 0.021
protein localization to synapse GO:0035418 11 0.021
glucose homeostasis GO:0042593 128 0.021
negative regulation of intracellular signal transduction GO:1902532 167 0.021
regulation of transmembrane transport GO:0034762 128 0.021
regulation of apoptotic signaling pathway GO:2001233 197 0.021
regulation of system process GO:0044057 200 0.021
renal system development GO:0072001 225 0.021
glycerolipid metabolic process GO:0046486 122 0.021
cellular amino acid metabolic process GO:0006520 103 0.020
response to organic cyclic compound GO:0014070 198 0.020
Rat
ribonucleotide catabolic process GO:0009261 208 0.020
peptide transport GO:0015833 133 0.020
regulation of cellular catabolic process GO:0031329 242 0.020
regulation of defense response GO:0031347 233 0.020
regulation of ras protein signal transduction GO:0046578 114 0.020
regulation of protein kinase activity GO:0045859 232 0.020
pole plasm assembly GO:0007315 2 0.020
developmental growth involved in morphogenesis GO:0060560 138 0.020
regulation of synaptic transmission glutamatergic GO:0051966 19 0.020
Mouse
adult behavior GO:0030534 135 0.019
Mouse
cell junction organization GO:0034330 77 0.019
mitotic cell cycle GO:0000278 195 0.019
cellular response to peptide GO:1901653 92 0.019
regulation of neuron projection development GO:0010975 169 0.019
regulation of synapse structural plasticity GO:0051823 4 0.019
stem cell development GO:0048864 219 0.019
response to peptide hormone GO:0043434 127 0.019
plasma membrane organization GO:0007009 90 0.019
regulation of synapse assembly GO:0051963 29 0.019
positive regulation of protein complex assembly GO:0031334 45 0.019
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.019
nucleobase containing small molecule metabolic process GO:0055086 352 0.019
potassium ion transport GO:0006813 52 0.019
lipid biosynthetic process GO:0008610 179 0.019
mitotic cell cycle process GO:1903047 159 0.019
neuron projection extension GO:1990138 64 0.019
sensory perception of touch GO:0050975 2 0.019
respiratory tube development GO:0030323 167 0.019
regulation of cell adhesion GO:0030155 154 0.019
cellular response to epidermal growth factor stimulus GO:0071364 4 0.019
response to inorganic substance GO:0010035 96 0.019
regulation of glutamate receptor signaling pathway GO:1900449 16 0.019
regulation of endopeptidase activity GO:0052548 89 0.019
heterocycle catabolic process GO:0046700 280 0.019
nucleocytoplasmic transport GO:0006913 139 0.018
neurotransmitter gated ion channel clustering GO:0072578 6 0.018
cellular response to cytokine stimulus GO:0071345 189 0.018
regulation of peptide transport GO:0090087 91 0.018
ribose phosphate metabolic process GO:0019693 291 0.018
wnt signaling pathway involved in forebrain neuroblast division GO:0021874 2 0.018
peptidyl amino acid modification GO:0018193 336 0.018
regulation of transporter activity GO:0032409 57 0.018
neuromuscular process GO:0050905 99 0.018
muscle cell differentiation GO:0042692 261 0.018
cellular response to growth factor stimulus GO:0071363 197 0.018
regulation of heart contraction GO:0008016 77 0.018
telencephalon development GO:0021537 186 0.018
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.018
carbohydrate homeostasis GO:0033500 128 0.018
regulation of canonical wnt signaling pathway GO:0060828 82 0.018
negative regulation of protein modification process GO:0031400 163 0.018
cell activation involved in immune response GO:0002263 126 0.018
purine nucleotide metabolic process GO:0006163 302 0.018
cellular response to monosaccharide stimulus GO:0071326 47 0.018
carbohydrate metabolic process GO:0005975 230 0.018
cellular glucose homeostasis GO:0001678 52 0.018
heart process GO:0003015 94 0.018
positive regulation of kinase activity GO:0033674 155 0.018
epithelial tube morphogenesis GO:0060562 303 0.017
regulation of voltage gated calcium channel activity GO:1901385 4 0.017
response to oxidative stress GO:0006979 123 0.017
midgut development GO:0007494 4 0.017
regulation of actin filament based process GO:0032970 99 0.017
actin filament bundle assembly GO:0051017 40 0.017
inclusion body assembly GO:0070841 3 0.017
lymphocyte proliferation GO:0046651 164 0.017
protein localization to nucleus GO:0034504 121 0.017
nuclear division GO:0000280 158 0.017
t cell activation GO:0042110 289 0.017
cellular response to acid chemical GO:0071229 68 0.017
exploration behavior GO:0035640 21 0.017
neurotransmitter secretion GO:0007269 62 0.017
Mouse
cell maturation GO:0048469 127 0.017
regulation of grooming behavior GO:2000821 4 0.017
stress activated protein kinase signaling cascade GO:0031098 81 0.017
regulation of cell size GO:0008361 72 0.017
positive regulation of peptide secretion GO:0002793 33 0.017
small molecule biosynthetic process GO:0044283 132 0.017
bone mineralization GO:0030282 54 0.017
negative regulation of molecular function GO:0044092 258 0.017
nucleotide catabolic process GO:0009166 217 0.017
rhythmic process GO:0048511 174 0.017
camp metabolic process GO:0046058 40 0.016
neuroblast division in subventricular zone GO:0021849 2 0.016
actin polymerization or depolymerization GO:0008154 54 0.016
hepaticobiliary system development GO:0061008 67 0.016
regulation of protein serine threonine kinase activity GO:0071900 157 0.016
locomotory behavior GO:0007626 195 0.016
microtubule based process GO:0007017 236 0.016
erk1 and erk2 cascade GO:0070371 77 0.016
purine ribonucleotide catabolic process GO:0009154 208 0.016
response to nutrient levels GO:0031667 109 0.016
mammary gland bud formation GO:0060615 2 0.016
monocarboxylic acid metabolic process GO:0032787 191 0.016
protein import into nucleus GO:0006606 95 0.016
gonad development GO:0008406 141 0.016
cell junction assembly GO:0034329 52 0.016
g1 s transition of mitotic cell cycle GO:0000082 57 0.016
negative regulation of phosphate metabolic process GO:0045936 184 0.016
ionotropic glutamate receptor signaling pathway GO:0035235 29 0.016
Mouse
intracellular mrna localization GO:0008298 4 0.016
positive regulation of protein kinase activity GO:0045860 144 0.016
positive regulation of hormone secretion GO:0046887 38 0.015
regulation of purine nucleotide metabolic process GO:1900542 169 0.015
muscle fiber development GO:0048747 76 0.015
connective tissue development GO:0061448 179 0.015
purine nucleoside metabolic process GO:0042278 241 0.015
negative regulation of protein phosphorylation GO:0001933 126 0.015
regulation of cellular protein catabolic process GO:1903362 61 0.015
epithelial cell proliferation GO:0050673 174 0.015
negative regulation of cell development GO:0010721 169 0.015
female gamete generation GO:0007292 74 0.015
vesicle organization GO:0016050 60 0.015
Mouse
generation of precursor metabolites and energy GO:0006091 103 0.015
action potential GO:0001508 78 0.015
response to ischemia GO:0002931 14 0.015
regulation of hippo signaling GO:0035330 1 0.015
negative regulation of cellular component organization GO:0051129 194 0.015
development of primary male sexual characteristics GO:0046546 88 0.015
development of primary sexual characteristics GO:0045137 143 0.015
nuclear import GO:0051170 95 0.015
regulation of fear response GO:1903365 2 0.015
regulation of cell activation GO:0050865 289 0.015
regulation of extent of cell growth GO:0061387 52 0.015
positive regulation of secretion by cell GO:1903532 114 0.015
male genitalia morphogenesis GO:0048808 4 0.015
protein localization to organelle GO:0033365 185 0.015
peptide secretion GO:0002790 114 0.015
regulation of inhibitory postsynaptic membrane potential GO:0060080 13 0.015
Mouse
glucose transport GO:0015758 56 0.015
nucleoside metabolic process GO:0009116 246 0.015
positive regulation of apoptotic process GO:0043065 217 0.015
regulation of ossification GO:0030278 112 0.015
purine nucleoside triphosphate catabolic process GO:0009146 203 0.015
maternal determination of anterior posterior axis embryo GO:0008358 2 0.015
regulation of actin cytoskeleton organization GO:0032956 84 0.015
response to growth factor GO:0070848 198 0.014
cyclic nucleotide metabolic process GO:0009187 59 0.014
regulation of peptide hormone secretion GO:0090276 75 0.014
negative regulation of transferase activity GO:0051348 85 0.014
glycoprotein biosynthetic process GO:0009101 89 0.014
mesonephros development GO:0001823 97 0.014
response to catecholamine GO:0071869 4 0.014
purine ribonucleotide biosynthetic process GO:0009152 59 0.014
synapse organization GO:0050808 125 0.014
protein oligomerization GO:0051259 67 0.014
response to insulin GO:0032868 100 0.014
lung development GO:0030324 164 0.014
cytosolic calcium ion homeostasis GO:0051480 70 0.014
regulation of protein catabolic process GO:0042176 108 0.014
adenylate cyclase inhibiting g protein coupled glutamate receptor signaling pathway GO:0007196 3 0.014
organic hydroxy compound metabolic process GO:1901615 203 0.014
stress activated mapk cascade GO:0051403 80 0.014
protein targeting GO:0006605 143 0.014
oocyte anterior posterior axis specification GO:0007314 2 0.014
cell junction maintenance GO:0034331 4 0.014
neuron migration GO:0001764 122 0.014
wnt signaling pathway GO:0016055 188 0.014
purine nucleotide biosynthetic process GO:0006164 65 0.014
negative regulation of monocyte extravasation GO:2000438 1 0.014
regulation of gliogenesis GO:0014013 50 0.014
organelle fission GO:0048285 170 0.014
energy derivation by oxidation of organic compounds GO:0015980 77 0.014
respiratory system development GO:0060541 190 0.014
regulation of cytoskeleton organization GO:0051493 122 0.014
cellular nitrogen compound catabolic process GO:0044270 280 0.014
negative regulation of canonical wnt signaling pathway GO:0090090 51 0.013
rac protein signal transduction GO:0016601 13 0.013
regulation of kinase activity GO:0043549 249 0.013
alcohol metabolic process GO:0006066 116 0.013
regulation of blood pressure GO:0008217 93 0.013
epidermis development GO:0008544 187 0.013
adaptive immune response GO:0002250 155 0.013
endomembrane system organization GO:0010256 147 0.013
regulation of actin filament length GO:0030832 45 0.013
striated muscle cell development GO:0055002 125 0.013
peptidyl serine modification GO:0018209 83 0.013
blood vessel morphogenesis GO:0048514 285 0.013
formation of organ boundary GO:0010160 1 0.013
positive regulation of cell cycle GO:0045787 92 0.013
embryonic epithelial tube formation GO:0001838 130 0.013
dna metabolic process GO:0006259 303 0.013
activation of mapk activity GO:0000187 59 0.013
vasoconstriction GO:0042310 27 0.013
regulation of erk1 and erk2 cascade GO:0070372 71 0.013
mesoderm development GO:0007498 100 0.013
cellular response to organic cyclic compound GO:0071407 87 0.013
cell division GO:0051301 120 0.013
g0 to g1 transition GO:0045023 3 0.013
negative regulation of dendritic spine morphogenesis GO:0061002 3 0.013
cellular response to carbohydrate stimulus GO:0071322 50 0.013
positive regulation of transferase activity GO:0051347 167 0.013
meiotic nuclear division GO:0007126 115 0.013
rho protein signal transduction GO:0007266 32 0.013
purine containing compound catabolic process GO:0072523 213 0.013
positive regulation of ion transmembrane transport GO:0034767 24 0.013
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.013
negative regulation of cell morphogenesis involved in differentiation GO:0010771 48 0.013
canonical wnt signaling pathway involved in regulation of cell proliferation GO:0044340 3 0.012
establishment of protein localization to membrane GO:0090150 54 0.012
negative regulation of cell migration GO:0030336 59 0.012
positive regulation of synapse structural plasticity GO:0051835 1 0.012
regulation of lipid metabolic process GO:0019216 118 0.012
organic cyclic compound catabolic process GO:1901361 295 0.012
regulation of neurotransmitter transport GO:0051588 35 0.012
Mouse
skeletal muscle organ development GO:0060538 163 0.012
ribonucleoside metabolic process GO:0009119 245 0.012
cellular response to peptide hormone stimulus GO:0071375 92 0.012
positive regulation of cell death GO:0010942 224 0.012
activation of mapkk activity GO:0000186 15 0.012
ribose phosphate biosynthetic process GO:0046390 59 0.012
cellular response to glucose stimulus GO:0071333 45 0.012
covalent chromatin modification GO:0016569 163 0.012
morphogenesis of embryonic epithelium GO:0016331 159 0.012
branching morphogenesis of an epithelial tube GO:0048754 159 0.012
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.012
cellular response to hexose stimulus GO:0071331 47 0.012
positive regulation of programmed cell death GO:0043068 218 0.012
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.012
camera type eye development GO:0043010 266 0.012
morphogenesis of a branching structure GO:0001763 203 0.012
negative regulation of map kinase activity GO:0043407 34 0.012
mitotic cytokinesis GO:0000281 4 0.012
central nervous system neuron differentiation GO:0021953 162 0.012
positive regulation of alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor activity GO:2000969 3 0.012
spermatid differentiation GO:0048515 115 0.012
regulation of wnt signaling pathway GO:0030111 123 0.012
camp biosynthetic process GO:0006171 31 0.012
negative regulation of wnt signaling pathway GO:0030178 73 0.012
negative regulation of kinase activity GO:0033673 81 0.012
chemotaxis GO:0006935 247 0.012
purine nucleoside monophosphate metabolic process GO:0009126 81 0.012
cell fate commitment GO:0045165 210 0.011
social behavior GO:0035176 21 0.011
apoptotic mitochondrial changes GO:0008637 48 0.011
regulation of cell division GO:0051302 76 0.011
mitral valve morphogenesis GO:0003183 4 0.011
oxidation reduction process GO:0055114 342 0.011
regulation of nucleotide metabolic process GO:0006140 169 0.011
regulation of calcium ion transmembrane transport GO:1903169 20 0.011
tube formation GO:0035148 140 0.011
establishment of protein localization to organelle GO:0072594 118 0.011
purine ribonucleoside catabolic process GO:0046130 205 0.011
cellular response to insulin stimulus GO:0032869 78 0.011
adherens junction assembly GO:0034333 22 0.011
forebrain development GO:0030900 302 0.011
axis elongation involved in somitogenesis GO:0090245 4 0.011
extracellular structure organization GO:0043062 148 0.011
regulation of g protein coupled receptor protein signaling pathway GO:0008277 37 0.011

Grik4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.025
inherited metabolic disorder DOID:655 0 0.025
disease of mental health DOID:150 0 0.012