Mus musculus

44 known processes

Chka

choline kinase alpha

(Aliases: Chk,Chetk-alpha,ChoK,EtnK-alpha)

Chka biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
heterocycle catabolic process GO:0046700 280 0.073
positive regulation of cellular catabolic process GO:0031331 148 0.067
nucleoside phosphate metabolic process GO:0006753 338 0.063
cellular lipid metabolic process GO:0044255 323 0.057
organic cyclic compound catabolic process GO:1901361 295 0.055
cellular nitrogen compound catabolic process GO:0044270 280 0.053
regulation of cellular catabolic process GO:0031329 242 0.053
nucleotide metabolic process GO:0009117 332 0.050
male meiosis i GO:0007141 16 0.049
spermatogenesis GO:0007283 284 0.049
nucleobase containing small molecule metabolic process GO:0055086 352 0.048
small gtpase mediated signal transduction GO:0007264 97 0.048
cellular homeostasis GO:0019725 240 0.047
cell type specific apoptotic process GO:0097285 268 0.045
purine nucleotide catabolic process GO:0006195 211 0.045
cellular amino acid metabolic process GO:0006520 103 0.045
regulation of transferase activity GO:0051338 263 0.044
cellular macromolecule catabolic process GO:0044265 206 0.044
negative regulation of molecular function GO:0044092 258 0.044
cation transport GO:0006812 399 0.043
regulation of gtp catabolic process GO:0033124 113 0.043
ras protein signal transduction GO:0007265 77 0.042
regulation of organelle organization GO:0033043 289 0.042
purine containing compound catabolic process GO:0072523 213 0.041
male gamete generation GO:0048232 285 0.040
mrna metabolic process GO:0016071 84 0.040
nitrogen compound transport GO:0071705 271 0.040
immune effector process GO:0002252 321 0.039
purine containing compound metabolic process GO:0072521 311 0.039
rna processing GO:0006396 105 0.039
rna splicing GO:0008380 54 0.038
oxidation reduction process GO:0055114 342 0.038
ribose phosphate metabolic process GO:0019693 291 0.038
aromatic compound catabolic process GO:0019439 286 0.038
regulation of nucleotide metabolic process GO:0006140 169 0.038
maintenance of location GO:0051235 89 0.037
Worm
regulation of purine nucleotide catabolic process GO:0033121 122 0.037
regulation of hydrolase activity GO:0051336 246 0.037
regulation of hormone levels GO:0010817 211 0.036
transmembrane transport GO:0055085 412 0.036
purine nucleoside triphosphate catabolic process GO:0009146 203 0.036
purine ribonucleotide metabolic process GO:0009150 290 0.035
purine nucleoside metabolic process GO:0042278 241 0.035
regulation of cell migration GO:0030334 219 0.035
regulation of kinase activity GO:0043549 249 0.035
organonitrogen compound catabolic process GO:1901565 264 0.035
regulation of protein kinase activity GO:0045859 232 0.035
purine ribonucleoside catabolic process GO:0046130 205 0.034
germ cell development GO:0007281 185 0.034
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.034
cellular amine metabolic process GO:0044106 44 0.033
actin cytoskeleton organization GO:0030036 220 0.033
cation homeostasis GO:0055080 212 0.033
apoptotic signaling pathway GO:0097190 306 0.033
nucleoside phosphate catabolic process GO:1901292 222 0.033
purine nucleotide metabolic process GO:0006163 302 0.033
mapk cascade GO:0000165 281 0.033
purine ribonucleotide catabolic process GO:0009154 208 0.033
regulation of cellular ketone metabolic process GO:0010565 66 0.033
ribonucleotide metabolic process GO:0009259 291 0.032
ribonucleoside metabolic process GO:0009119 245 0.032
nucleoside triphosphate metabolic process GO:0009141 230 0.032
purine ribonucleoside metabolic process GO:0046128 241 0.032
regulation of cellular amino acid metabolic process GO:0006521 5 0.032
nucleoside metabolic process GO:0009116 246 0.032
regulation of mapk cascade GO:0043408 248 0.031
glycosyl compound metabolic process GO:1901657 246 0.031
cellular chemical homeostasis GO:0055082 215 0.031
carbohydrate derivative catabolic process GO:1901136 231 0.030
response to radiation GO:0009314 165 0.030
ribonucleoside triphosphate catabolic process GO:0009203 199 0.030
mrna processing GO:0006397 63 0.030
negative regulation of protein metabolic process GO:0051248 282 0.030
homeostasis of number of cells GO:0048872 210 0.029
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.029
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.029
positive regulation of apoptotic process GO:0043065 217 0.029
epithelial cell development GO:0002064 159 0.029
nucleoside catabolic process GO:0009164 206 0.029
hormone metabolic process GO:0042445 86 0.028
regulation of rna splicing GO:0043484 37 0.028
endomembrane system organization GO:0010256 147 0.028
ribonucleoside triphosphate metabolic process GO:0009199 220 0.028
synaptic transmission GO:0007268 329 0.028
response to oxidative stress GO:0006979 123 0.027
gtp catabolic process GO:0006184 143 0.027
membrane organization GO:0061024 245 0.027
response to organonitrogen compound GO:0010243 246 0.027
regulation of cellular response to stress GO:0080135 159 0.027
gtp metabolic process GO:0046039 144 0.027
organonitrogen compound biosynthetic process GO:1901566 192 0.027
regulation of nucleotide catabolic process GO:0030811 122 0.026
glycosyl compound catabolic process GO:1901658 206 0.026
cellular response to dna damage stimulus GO:0006974 207 0.026
ribonucleotide catabolic process GO:0009261 208 0.026
cellular ketone metabolic process GO:0042180 84 0.026
metal ion homeostasis GO:0055065 189 0.026
rho protein signal transduction GO:0007266 32 0.025
organic acid transport GO:0015849 101 0.025
ubiquitin dependent protein catabolic process GO:0006511 129 0.025
regulation of cell motility GO:2000145 236 0.025
organophosphate catabolic process GO:0046434 232 0.025
regulation of homeostatic process GO:0032844 182 0.025
cytokine production GO:0001816 319 0.025
positive regulation of transferase activity GO:0051347 167 0.024
cytoplasmic transport GO:0016482 234 0.024
negative regulation of cellular protein metabolic process GO:0032269 247 0.024
circulatory system process GO:0003013 197 0.024
regulation of system process GO:0044057 200 0.024
ion transmembrane transport GO:0034220 361 0.024
nucleotide catabolic process GO:0009166 217 0.024
monocarboxylic acid metabolic process GO:0032787 191 0.024
multicellular organismal homeostasis GO:0048871 164 0.024
negative regulation of phosphorus metabolic process GO:0010563 184 0.024
macromolecule catabolic process GO:0009057 281 0.024
amine metabolic process GO:0009308 45 0.023
anion transport GO:0006820 177 0.023
response to organic cyclic compound GO:0014070 198 0.023
carboxylic acid biosynthetic process GO:0046394 86 0.023
muscle cell differentiation GO:0042692 261 0.023
purine nucleoside triphosphate metabolic process GO:0009144 226 0.023
cell adhesion GO:0007155 329 0.023
positive regulation of kinase activity GO:0033674 155 0.023
negative regulation of intracellular signal transduction GO:1902532 167 0.023
positive regulation of nucleoside metabolic process GO:0045979 91 0.023
response to inorganic substance GO:0010035 96 0.023
nucleoside triphosphate catabolic process GO:0009143 205 0.023
purine nucleoside catabolic process GO:0006152 205 0.023
calcium ion homeostasis GO:0055074 127 0.022
regulation of protein serine threonine kinase activity GO:0071900 157 0.022
myeloid cell differentiation GO:0030099 233 0.022
positive regulation of protein phosphorylation GO:0001934 242 0.022
regulation of anatomical structure size GO:0090066 178 0.022
cellular ion homeostasis GO:0006873 165 0.022
small molecule biosynthetic process GO:0044283 132 0.021
regulation of membrane potential GO:0042391 192 0.021
guanosine containing compound metabolic process GO:1901068 144 0.021
carbohydrate metabolic process GO:0005975 230 0.021
positive regulation of hydrolase activity GO:0051345 148 0.021
positive regulation of programmed cell death GO:0043068 218 0.021
negative regulation of cell proliferation GO:0008285 296 0.021
organic acid biosynthetic process GO:0016053 86 0.021
meiotic cell cycle process GO:1903046 77 0.021
organelle fission GO:0048285 170 0.021
heart morphogenesis GO:0003007 178 0.021
meiosis i GO:0007127 60 0.021
camera type eye development GO:0043010 266 0.021
regulation of purine nucleotide metabolic process GO:1900542 169 0.020
intrinsic apoptotic signaling pathway GO:0097193 132 0.020
organelle localization GO:0051640 179 0.020
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.020
male meiosis GO:0007140 37 0.020
sensory perception GO:0007600 245 0.020
regulation of ion transport GO:0043269 215 0.020
neuron death GO:0070997 154 0.020
dna metabolic process GO:0006259 303 0.019
anatomical structure homeostasis GO:0060249 145 0.019
cation transmembrane transport GO:0098655 266 0.019
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.019
protein modification by small protein conjugation GO:0032446 187 0.019
meiotic cell cycle GO:0051321 122 0.019
ribonucleoside catabolic process GO:0042454 206 0.019
negative regulation of phosphorylation GO:0042326 166 0.019
positive regulation of cellular amine metabolic process GO:0033240 5 0.019
lateral line system development GO:0048925 1 0.019
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.019
positive regulation of cell death GO:0010942 224 0.019
regulation of nucleoside metabolic process GO:0009118 130 0.019
asymmetric stem cell division GO:0098722 3 0.019
multicellular organism growth GO:0035264 161 0.018
Mouse
positive regulation of gtpase activity GO:0043547 85 0.018
carboxylic acid transport GO:0046942 100 0.018
cell cell junction organization GO:0045216 72 0.018
synapse organization GO:0050808 125 0.018
fatty acid metabolic process GO:0006631 121 0.018
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.018
cellular divalent inorganic cation homeostasis GO:0072503 127 0.018
lymphocyte mediated immunity GO:0002449 139 0.018
cellular metal ion homeostasis GO:0006875 151 0.018
blastocyst development GO:0001824 80 0.018
organic hydroxy compound metabolic process GO:1901615 203 0.018
microtubule based process GO:0007017 236 0.017
blood circulation GO:0008015 195 0.017
positive regulation of protein modification process GO:0031401 299 0.017
chromatin modification GO:0016568 187 0.017
sensory organ morphogenesis GO:0090596 242 0.017
positive regulation of nucleotide metabolic process GO:0045981 114 0.017
neuronal action potential GO:0019228 54 0.017
divalent inorganic cation transport GO:0072511 178 0.017
divalent inorganic cation homeostasis GO:0072507 138 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.017
positive regulation of mapk cascade GO:0043410 170 0.017
locomotory behavior GO:0007626 195 0.017
inorganic cation transmembrane transport GO:0098662 207 0.017
posttranscriptional regulation of gene expression GO:0010608 155 0.017
positive regulation of organelle organization GO:0010638 128 0.017
regulation of neuron death GO:1901214 134 0.017
organic anion transport GO:0015711 137 0.017
regulation of map kinase activity GO:0043405 120 0.017
response to light stimulus GO:0009416 135 0.017
positive regulation of protein kinase activity GO:0045860 144 0.017
exocytosis GO:0006887 121 0.016
action potential GO:0001508 78 0.016
zygotic determination of anterior posterior axis embryo GO:0007354 3 0.016
sensory system development GO:0048880 3 0.016
rna splicing via transesterification reactions GO:0000375 43 0.016
positive regulation of nucleotide catabolic process GO:0030813 88 0.016
regulation of secretion GO:0051046 274 0.016
cellular calcium ion homeostasis GO:0006874 119 0.016
regulation of apoptotic signaling pathway GO:2001233 197 0.016
guanosine containing compound catabolic process GO:1901069 144 0.016
blood vessel morphogenesis GO:0048514 285 0.016
skeletal system development GO:0001501 356 0.016
anion transmembrane transport GO:0098656 71 0.016
regulation of neuron apoptotic process GO:0043523 122 0.016
protein ubiquitination GO:0016567 171 0.016
multicellular organismal signaling GO:0035637 91 0.016
divalent metal ion transport GO:0070838 172 0.015
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.015
regulation of cytoskeleton organization GO:0051493 122 0.015
respiratory tube development GO:0030323 167 0.015
cellular response to lipid GO:0071396 145 0.015
gland development GO:0048732 330 0.015
reactive oxygen species metabolic process GO:0072593 84 0.015
regulation of cellular component biogenesis GO:0044087 181 0.015
negative regulation of phosphate metabolic process GO:0045936 184 0.015
circadian regulation of gene expression GO:0032922 48 0.015
organelle assembly GO:0070925 177 0.015
extracellular structure organization GO:0043062 148 0.015
sequestering of metal ion GO:0051238 19 0.015
nuclear transport GO:0051169 139 0.015
innate immune response GO:0045087 157 0.015
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 3 0.015
cell activation involved in immune response GO:0002263 126 0.015
tissue homeostasis GO:0001894 115 0.015
inorganic ion transmembrane transport GO:0098660 234 0.015
positive regulation of gtp catabolic process GO:0033126 85 0.015
chromatin organization GO:0006325 206 0.015
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.015
muscle system process GO:0003012 141 0.015
telencephalon development GO:0021537 186 0.015
regionalization GO:0003002 337 0.015
regulation of protein localization GO:0032880 231 0.015
meiotic nuclear division GO:0007126 115 0.014
regulation of cellular component size GO:0032535 121 0.014
central nervous system neuron differentiation GO:0021953 162 0.014
neural tube development GO:0021915 160 0.014
canonical wnt signaling pathway GO:0060070 130 0.014
leukocyte mediated immunity GO:0002443 174 0.014
epithelial tube formation GO:0072175 130 0.014
glycerolipid metabolic process GO:0046486 122 0.014
morphogenesis of embryonic epithelium GO:0016331 159 0.014
cellular response to organonitrogen compound GO:0071417 145 0.014
respiratory system development GO:0060541 190 0.014
ossification GO:0001503 216 0.014
regulation of cell projection organization GO:0031344 206 0.014
amino acid transport GO:0006865 61 0.014
spermatid differentiation GO:0048515 115 0.014
phospholipid metabolic process GO:0006644 87 0.014
response to peptide GO:1901652 136 0.014
peptidyl amino acid modification GO:0018193 336 0.014
regulation of cell cycle GO:0051726 281 0.014
nuclear division GO:0000280 158 0.014
epithelium migration GO:0090132 63 0.014
negative regulation of fat cell proliferation GO:0070345 2 0.014
endocytosis GO:0006897 168 0.014
carbohydrate derivative biosynthetic process GO:1901137 183 0.014
cellular response to hormone stimulus GO:0032870 150 0.014
modification dependent macromolecule catabolic process GO:0043632 133 0.014
rna interference GO:0016246 2 0.014
muscle tissue development GO:0060537 308 0.013
regulation of intracellular transport GO:0032386 159 0.013
regulation of metal ion transport GO:0010959 106 0.013
mrna splicing via spliceosome GO:0000398 43 0.013
l amino acid transport GO:0015807 32 0.013
proteasomal protein catabolic process GO:0010498 98 0.013
monocarboxylic acid biosynthetic process GO:0072330 61 0.013
regulation of mrna metabolic process GO:1903311 43 0.013
negative regulation of protein modification process GO:0031400 163 0.013
rap protein signal transduction GO:0032486 3 0.013
neuron apoptotic process GO:0051402 142 0.013
positive regulation of cell development GO:0010720 237 0.013
negative regulation of immune system process GO:0002683 209 0.013
response to reactive oxygen species GO:0000302 56 0.013
blastocyst growth GO:0001832 23 0.013
jnk cascade GO:0007254 72 0.013
protein localization to organelle GO:0033365 185 0.013
forebrain development GO:0030900 302 0.013
lipid modification GO:0030258 65 0.013
response to extracellular stimulus GO:0009991 127 0.013
nucleocytoplasmic transport GO:0006913 139 0.012
regulation of actin filament based process GO:0032970 99 0.012
adaptive immune response GO:0002250 155 0.012
regulation of cytoplasmic transport GO:1903649 112 0.012
tube formation GO:0035148 140 0.012
regulation of ion transmembrane transport GO:0034765 119 0.012
spermatid development GO:0007286 108 0.012
neuromuscular process GO:0050905 99 0.012
sequestering of calcium ion GO:0051208 18 0.012
protein oligomerization GO:0051259 67 0.012
embryonic epithelial tube formation GO:0001838 130 0.012
regulation of multi organism process GO:0043900 111 0.012
macromolecule methylation GO:0043414 120 0.012
intracellular receptor signaling pathway GO:0030522 74 0.012
cellular alcohol biosynthetic process GO:0044108 3 0.012
placenta development GO:0001890 140 0.012
Mouse
axonogenesis GO:0007409 274 0.012
chromosome segregation GO:0007059 48 0.012
regulation of cytokine production GO:0001817 266 0.012
plasma membrane organization GO:0007009 90 0.012
leukocyte differentiation GO:0002521 342 0.012
protein catabolic process GO:0030163 221 0.012
regulation of cell adhesion GO:0030155 154 0.012
regulation of reactive oxygen species metabolic process GO:2000377 40 0.012
lipid localization GO:0010876 126 0.012
Worm
organic hydroxy compound biosynthetic process GO:1901617 77 0.012
stress activated mapk cascade GO:0051403 80 0.012
neural tube closure GO:0001843 90 0.012
epidermis development GO:0008544 187 0.011
protein processing GO:0016485 163 0.011
lateral inhibition GO:0046331 1 0.011
alpha amino acid metabolic process GO:1901605 59 0.011
actin filament based movement GO:0030048 23 0.011
regulation of proteolysis GO:0030162 164 0.011
regulation of cell activation GO:0050865 289 0.011
pole plasm assembly GO:0007315 2 0.011
myeloid leukocyte activation GO:0002274 83 0.011
cell division GO:0051301 120 0.011
g protein coupled receptor signaling pathway GO:0007186 243 0.011
response to acid chemical GO:0001101 111 0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.011
striated muscle tissue development GO:0014706 293 0.011
ear morphogenesis GO:0042471 118 0.011
reactive nitrogen species metabolic process GO:2001057 0 0.011
t cell activation GO:0042110 289 0.011
angiogenesis GO:0001525 201 0.011
regulation of ras gtpase activity GO:0032318 88 0.011
negative regulation of protein phosphorylation GO:0001933 126 0.011
lipid biosynthetic process GO:0008610 179 0.011
intracellular steroid hormone receptor signaling pathway GO:0030518 29 0.011
negative regulation of transferase activity GO:0051348 85 0.011
myeloid cell homeostasis GO:0002262 114 0.011
negative regulation of synapse assembly GO:0051964 3 0.011
lung development GO:0030324 164 0.011
response to growth factor GO:0070848 198 0.011
methylation GO:0032259 134 0.011
adult behavior GO:0030534 135 0.011
negative regulation of cellular component organization GO:0051129 194 0.011
cognition GO:0050890 149 0.011
histone deubiquitination GO:0016578 2 0.011
cellularization GO:0007349 1 0.011
actin filament organization GO:0007015 113 0.011
ameboidal type cell migration GO:0001667 128 0.011
negative regulation of protein kinase activity by regulation of protein phosphorylation GO:0044387 2 0.011
negative regulation of cell motility GO:2000146 61 0.011
small molecule catabolic process GO:0044282 71 0.011
myosin filament assembly GO:0031034 2 0.011
purine nucleoside monophosphate metabolic process GO:0009126 81 0.011
response to epidermal growth factor GO:0070849 4 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.010
cellular response to cytokine stimulus GO:0071345 189 0.010
regulation of defense response GO:0031347 233 0.010
retrograde transport endosome to golgi GO:0042147 2 0.010
protein maturation GO:0051604 176 0.010
cellular protein catabolic process GO:0044257 155 0.010
regulation of actin cytoskeleton organization GO:0032956 84 0.010
amide transport GO:0042886 138 0.010
response to insulin GO:0032868 100 0.010
interleukin 8 production GO:0032637 4 0.010
epithelial tube morphogenesis GO:0060562 303 0.010
organophosphate biosynthetic process GO:0090407 122 0.010
calcium ion transport GO:0006816 159 0.010
generation of precursor metabolites and energy GO:0006091 103 0.010
dephosphorylation GO:0016311 129 0.010
phosphatidylethanolamine biosynthetic process GO:0006646 2 0.010
Human Mouse
regulation of establishment of protein localization GO:0070201 181 0.010
regulation of lymphocyte activation GO:0051249 240 0.010
cell maturation GO:0048469 127 0.010
carboxylic acid catabolic process GO:0046395 51 0.010
hexose metabolic process GO:0019318 98 0.010
limb development GO:0060173 166 0.010
embryonic organ morphogenesis GO:0048562 276 0.010
skeletal system morphogenesis GO:0048705 203 0.010
learning or memory GO:0007611 148 0.010
mitochondrion organization GO:0007005 134 0.010
protein localization to nucleus GO:0034504 121 0.010
regulation of cellular amine metabolic process GO:0033238 20 0.010
protein localization to membrane GO:0072657 108 0.010
epithelial cell proliferation GO:0050673 174 0.010
response to peptide hormone GO:0043434 127 0.010
alpha beta t cell activation GO:0046631 91 0.010
protein modification by small protein conjugation or removal GO:0070647 207 0.010
negative regulation of cellular amine metabolic process GO:0033239 1 0.010

Chka disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.031
nervous system disease DOID:863 0 0.031
disease of metabolism DOID:0014667 0 0.022
inherited metabolic disorder DOID:655 0 0.018
musculoskeletal system disease DOID:17 0 0.016
connective tissue disease DOID:65 0 0.016
immune system disease DOID:2914 0 0.016
hematopoietic system disease DOID:74 0 0.015
bone disease DOID:0080001 0 0.013
neuromuscular disease DOID:440 0 0.011
neuropathy DOID:870 0 0.011