Mus musculus

0 known processes

Ints6

integrator complex subunit 6

(Aliases: 2900075H24Rik,Ddx26,Notch2l,HDB,DICE1,AI480962)

Ints6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
modification dependent macromolecule catabolic process GO:0043632 133 0.258
ubiquitin dependent protein catabolic process GO:0006511 129 0.190
protein catabolic process GO:0030163 221 0.124
cellular protein catabolic process GO:0044257 155 0.121
modification dependent protein catabolic process GO:0019941 133 0.110
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.101
myeloid cell differentiation GO:0030099 233 0.089
rna processing GO:0006396 105 0.079
Human
mitotic cell cycle GO:0000278 195 0.076
homeostasis of number of cells GO:0048872 210 0.075
apoptotic signaling pathway GO:0097190 306 0.068
cellular macromolecule catabolic process GO:0044265 206 0.067
mitotic cell cycle process GO:1903047 159 0.064
protein ubiquitination GO:0016567 171 0.060
organelle fission GO:0048285 170 0.058
cellular response to dna damage stimulus GO:0006974 207 0.056
macromolecule catabolic process GO:0009057 281 0.056
cation transport GO:0006812 399 0.050
transmembrane transport GO:0055085 412 0.049
posttranscriptional regulation of gene expression GO:0010608 155 0.049
forebrain development GO:0030900 302 0.049
negative regulation of immune system process GO:0002683 209 0.047
protein modification by small protein conjugation GO:0032446 187 0.047
spermatogenesis GO:0007283 284 0.046
regulation of cellular amino acid metabolic process GO:0006521 5 0.046
regulation of apoptotic signaling pathway GO:2001233 197 0.045
mrna metabolic process GO:0016071 84 0.045
cellular amino acid metabolic process GO:0006520 103 0.044
covalent chromatin modification GO:0016569 163 0.044
chromatin modification GO:0016568 187 0.042
cellular ketone metabolic process GO:0042180 84 0.042
protein methylation GO:0006479 81 0.039
hematopoietic progenitor cell differentiation GO:0002244 143 0.038
dna metabolic process GO:0006259 303 0.038
ion transmembrane transport GO:0034220 361 0.036
negative regulation of lymphocyte activation GO:0051250 91 0.034
regulation of cellular ketone metabolic process GO:0010565 66 0.033
response to radiation GO:0009314 165 0.032
regulation of organelle organization GO:0033043 289 0.032
cellular homeostasis GO:0019725 240 0.031
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.030
negative regulation of protein metabolic process GO:0051248 282 0.030
positive regulation of cellular catabolic process GO:0031331 148 0.029
nuclear division GO:0000280 158 0.029
actin cytoskeleton organization GO:0030036 220 0.028
cellular amine metabolic process GO:0044106 44 0.028
myeloid cell homeostasis GO:0002262 114 0.028
protein homotrimerization GO:0070207 4 0.027
cation homeostasis GO:0055080 212 0.026
microtubule cytoskeleton organization GO:0000226 157 0.026
multicellular organism growth GO:0035264 161 0.026
spleen development GO:0048536 39 0.026
regulation of hormone levels GO:0010817 211 0.026
negative regulation of t helper 2 cell differentiation GO:0045629 4 0.025
development of primary sexual characteristics GO:0045137 143 0.025
immune effector process GO:0002252 321 0.024
mrna processing GO:0006397 63 0.024
extrinsic apoptotic signaling pathway GO:0097191 126 0.024
dna repair GO:0006281 107 0.024
sensory perception GO:0007600 245 0.023
cellular chemical homeostasis GO:0055082 215 0.023
leukocyte differentiation GO:0002521 342 0.023
inorganic ion transmembrane transport GO:0098660 234 0.023
gland development GO:0048732 330 0.023
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.023
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.022
gonad development GO:0008406 141 0.022
male gamete generation GO:0048232 285 0.022
macromolecule methylation GO:0043414 120 0.022
intracellular protein transport GO:0006886 204 0.022
regulation of intracellular transport GO:0032386 159 0.022
dna recombination GO:0006310 92 0.022
macromolecule deacylation GO:0098732 37 0.022
respiratory tube development GO:0030323 167 0.022
protein modification by small protein conjugation or removal GO:0070647 207 0.022
negative regulation of molecular function GO:0044092 258 0.022
wound healing GO:0042060 157 0.022
negative regulation of t cell activation GO:0050868 65 0.022
positive regulation of cellular amine metabolic process GO:0033240 5 0.022
negative regulation of cellular protein metabolic process GO:0032269 247 0.021
erythrocyte differentiation GO:0030218 88 0.021
nucleoside phosphate metabolic process GO:0006753 338 0.021
t cell activation GO:0042110 289 0.021
compound eye development GO:0048749 1 0.021
regulation of cellular amine metabolic process GO:0033238 20 0.021
cellular ion homeostasis GO:0006873 165 0.021
regulation of cellular catabolic process GO:0031329 242 0.021
purine containing compound metabolic process GO:0072521 311 0.021
proteasomal protein catabolic process GO:0010498 98 0.021
leukocyte activation involved in immune response GO:0002366 126 0.021
regulation of secretion by cell GO:1903530 249 0.020
histone modification GO:0016570 159 0.020
negative regulation of protein modification process GO:0031400 163 0.020
regulation of cell activation GO:0050865 289 0.020
camera type eye development GO:0043010 266 0.020
negative regulation of proteolysis GO:0045861 74 0.020
divalent inorganic cation homeostasis GO:0072507 138 0.020
regulation of protein localization GO:0032880 231 0.020
cation transmembrane transport GO:0098655 266 0.020
chromatin organization GO:0006325 206 0.019
respiratory system development GO:0060541 190 0.019
spinal cord oligodendrocyte cell differentiation GO:0021529 3 0.019
positive regulation of programmed cell death GO:0043068 218 0.019
regulation of cell cycle GO:0051726 281 0.019
rna interference GO:0016246 2 0.019
chromosome segregation GO:0007059 48 0.019
regulation of chromosome organization GO:0033044 83 0.019
amine metabolic process GO:0009308 45 0.018
epithelial cell proliferation GO:0050673 174 0.018
protein maturation GO:0051604 176 0.018
wnt signaling pathway GO:0016055 188 0.018
regulation of protein processing GO:0070613 96 0.018
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.018
cell activation involved in immune response GO:0002263 126 0.018
regulation of myeloid cell differentiation GO:0045637 96 0.018
transition metal ion transport GO:0000041 38 0.018
regulation of protein stability GO:0031647 52 0.018
negative regulation of synapse assembly GO:0051964 3 0.018
bmp signaling pathway GO:0030509 93 0.017
negative regulation of cell activation GO:0050866 111 0.017
regulation of protein maturation GO:1903317 96 0.017
ribose phosphate metabolic process GO:0019693 291 0.017
negative regulation of phosphorylation GO:0042326 166 0.017
regulation of establishment of protein localization GO:0070201 181 0.017
cellular metal ion homeostasis GO:0006875 151 0.017
skeletal system development GO:0001501 356 0.017
regulation of lymphocyte activation GO:0051249 240 0.017
negative regulation of organelle organization GO:0010639 90 0.016
ossification GO:0001503 216 0.016
metal ion homeostasis GO:0055065 189 0.016
divalent metal ion transport GO:0070838 172 0.016
divalent inorganic cation transport GO:0072511 178 0.016
epithelial cell development GO:0002064 159 0.016
skin development GO:0043588 220 0.016
glucose homeostasis GO:0042593 128 0.016
regulation of t cell activation GO:0050863 170 0.016
nitrogen compound transport GO:0071705 271 0.016
regulation of epithelial cell proliferation GO:0050678 141 0.016
protein localization to organelle GO:0033365 185 0.016
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.016
heterocycle catabolic process GO:0046700 280 0.016
response to testosterone GO:0033574 3 0.016
inorganic cation transmembrane transport GO:0098662 207 0.016
lung development GO:0030324 164 0.015
intrinsic apoptotic signaling pathway GO:0097193 132 0.015
negative regulation of intracellular signal transduction GO:1902532 167 0.015
immune response activating signal transduction GO:0002757 116 0.015
regulation of alpha beta t cell activation GO:0046634 53 0.015
regulation of cell cycle process GO:0010564 160 0.015
negative regulation of phosphate metabolic process GO:0045936 184 0.015
sensory organ morphogenesis GO:0090596 242 0.015
cellular nitrogen compound catabolic process GO:0044270 280 0.015
cell adhesion GO:0007155 329 0.015
stem cell development GO:0048864 219 0.015
defecation GO:0030421 1 0.015
fibroblast proliferation GO:0048144 35 0.015
purine nucleoside monophosphate metabolic process GO:0009126 81 0.014
glycerolipid metabolic process GO:0046486 122 0.014
positive regulation of cellular component biogenesis GO:0044089 94 0.014
cytoplasmic transport GO:0016482 234 0.014
calcium ion transport GO:0006816 159 0.014
oocyte axis specification GO:0007309 2 0.014
positive regulation of macroautophagy GO:0016239 3 0.014
t cell differentiation GO:0030217 174 0.014
calcium ion homeostasis GO:0055074 127 0.014
positive regulation of nervous system development GO:0051962 221 0.014
adaptive immune response GO:0002250 155 0.014
regulation of membrane potential GO:0042391 192 0.014
rna splicing via transesterification reactions GO:0000375 43 0.014
double strand break repair GO:0006302 48 0.014
demethylation GO:0070988 23 0.014
meiotic cell cycle GO:0051321 122 0.014
cellular response to lipid GO:0071396 145 0.013
maintenance of location GO:0051235 89 0.013
sodium ion transport GO:0006814 73 0.013
g1 s transition of mitotic cell cycle GO:0000082 57 0.013
response to light stimulus GO:0009416 135 0.013
defense response to other organism GO:0098542 197 0.013
lipid localization GO:0010876 126 0.013
regulation of cellular component size GO:0032535 121 0.013
germ cell development GO:0007281 185 0.013
rna 3 end processing GO:0031123 20 0.013
cell division GO:0051301 120 0.013
negative regulation of cellular component organization GO:0051129 194 0.013
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.013
regulation of mitotic cell cycle GO:0007346 126 0.013
regulation of secretion GO:0051046 274 0.013
response to organic cyclic compound GO:0014070 198 0.013
regulation of protein import into nucleus GO:0042306 52 0.013
endocytosis GO:0006897 168 0.013
regulation of response to alcohol GO:1901419 2 0.013
telencephalon development GO:0021537 186 0.013
mrna 3 end processing GO:0031124 16 0.013
organelle assembly GO:0070925 177 0.013
response to temperature stimulus GO:0009266 55 0.013
methylation GO:0032259 134 0.013
peptidyl amino acid modification GO:0018193 336 0.013
cellular calcium ion homeostasis GO:0006874 119 0.012
regulation of wnt signaling pathway GO:0030111 123 0.012
positive regulation of protein modification process GO:0031401 299 0.012
glycosyl compound metabolic process GO:1901657 246 0.012
epidermis development GO:0008544 187 0.012
spinal cord development GO:0021510 81 0.012
nucleotide metabolic process GO:0009117 332 0.012
gene silencing GO:0016458 38 0.012
regulation of protein catabolic process GO:0042176 108 0.012
fat cell differentiation GO:0045444 160 0.012
regulation of histone modification GO:0031056 56 0.012
negative regulation of alpha beta t cell activation GO:0046636 18 0.012
regulation of ion transport GO:0043269 215 0.012
lymphocyte mediated immunity GO:0002449 139 0.012
regulation of lymphocyte differentiation GO:0045619 107 0.012
positive regulation of organelle organization GO:0010638 128 0.012
ribonucleoside monophosphate metabolic process GO:0009161 80 0.012
negative regulation of protein processing GO:0010955 79 0.012
negative regulation of phosphorus metabolic process GO:0010563 184 0.012
aromatic compound catabolic process GO:0019439 286 0.012
regulation of nucleocytoplasmic transport GO:0046822 73 0.012
cellular response to abiotic stimulus GO:0071214 56 0.012
nucleoside metabolic process GO:0009116 246 0.012
intracellular receptor signaling pathway GO:0030522 74 0.012
appendage development GO:0048736 166 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.012
cellular response to organic cyclic compound GO:0071407 87 0.012
microtubule based process GO:0007017 236 0.012
regulation of stem cell proliferation GO:0072091 78 0.012
regulation of proteasomal protein catabolic process GO:0061136 46 0.012
morphogenesis of a branching epithelium GO:0061138 193 0.011
muscle tissue development GO:0060537 308 0.011
ribonucleotide metabolic process GO:0009259 291 0.011
lymphocyte activation involved in immune response GO:0002285 93 0.011
regulation of cell cycle phase transition GO:1901987 77 0.011
cd4 positive alpha beta t cell activation GO:0035710 45 0.011
cardiac chamber morphogenesis GO:0003206 93 0.011
nucleobase containing small molecule metabolic process GO:0055086 352 0.011
regulation of proteolysis GO:0030162 164 0.011
negative regulation of cell proliferation GO:0008285 296 0.011
translation GO:0006412 93 0.011
positive regulation of fatty acid biosynthetic process GO:0045723 3 0.011
negative regulation of cell cycle phase transition GO:1901988 48 0.011
carboxylic acid biosynthetic process GO:0046394 86 0.011
muscle cell differentiation GO:0042692 261 0.011
cellular response to radiation GO:0071478 28 0.011
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.011
cognition GO:0050890 149 0.011
cell maturation GO:0048469 127 0.011
nucleoside monophosphate metabolic process GO:0009123 85 0.011
lymphocyte differentiation GO:0030098 242 0.011
regulation of response to wounding GO:1903034 189 0.011
striated muscle tissue development GO:0014706 293 0.011
protein polyubiquitination GO:0000209 33 0.011
gastrulation GO:0007369 116 0.011
positive regulation of glial cell proliferation GO:0060252 4 0.011
regulation of protein transport GO:0051223 163 0.011
cell growth GO:0016049 130 0.011
digestive tract development GO:0048565 190 0.011
epithelial tube morphogenesis GO:0060562 303 0.011
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 3 0.011
negative regulation of myeloid cell differentiation GO:0045638 38 0.011
intracellular steroid hormone receptor signaling pathway GO:0030518 29 0.011
ribonucleoside triphosphate metabolic process GO:0009199 220 0.010
regulation of cellular response to stress GO:0080135 159 0.010
aortic valve morphogenesis GO:0003180 4 0.010
positive regulation of histone h3 k9 methylation GO:0051574 4 0.010
negative regulation of immune effector process GO:0002698 55 0.010
purine ribonucleoside metabolic process GO:0046128 241 0.010
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.010
positive regulation of cell cycle GO:0045787 92 0.010
blood circulation GO:0008015 195 0.010
regulation of cytoplasmic transport GO:1903649 112 0.010
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.010
coenzyme biosynthetic process GO:0009108 23 0.010
mitotic nuclear division GO:0007067 48 0.010
regulation of transferase activity GO:0051338 263 0.010
blood vessel morphogenesis GO:0048514 285 0.010
anion transport GO:0006820 177 0.010
cardiac muscle tissue development GO:0048738 130 0.010
histone h3 k9 acetylation GO:0043970 5 0.010
regulation of cellular protein catabolic process GO:1903362 61 0.010
nuclear transport GO:0051169 139 0.010

Ints6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.105
disease of cellular proliferation DOID:14566 0 0.105
organ system cancer DOID:0050686 0 0.105