Mus musculus

35 known processes

Polg

polymerase (DNA directed), gamma

(Aliases: PolgA,AA409516)

Polg biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ribonucleotide metabolic process GO:0009259 291 0.138
defense response to other organism GO:0098542 197 0.119
transmembrane transport GO:0055085 412 0.118
cellular ketone metabolic process GO:0042180 84 0.115
regulation of hydrolase activity GO:0051336 246 0.099
small gtpase mediated signal transduction GO:0007264 97 0.099
cytokine production GO:0001816 319 0.094
immune effector process GO:0002252 321 0.089
ras protein signal transduction GO:0007265 77 0.088
organic cyclic compound catabolic process GO:1901361 295 0.081
glycosyl compound metabolic process GO:1901657 246 0.080
glycosyl compound catabolic process GO:1901658 206 0.079
ribonucleotide catabolic process GO:0009261 208 0.076
dna metabolic process GO:0006259 303 0.076
amine metabolic process GO:0009308 45 0.075
regulation of cellular catabolic process GO:0031329 242 0.073
heterocycle catabolic process GO:0046700 280 0.072
nucleoside phosphate metabolic process GO:0006753 338 0.071
positive regulation of hydrolase activity GO:0051345 148 0.070
leukocyte differentiation GO:0002521 342 0.070
covalent chromatin modification GO:0016569 163 0.069
cellular amine metabolic process GO:0044106 44 0.068
nucleobase containing small molecule metabolic process GO:0055086 352 0.066
homeostasis of number of cells GO:0048872 210 0.062
peptidyl amino acid modification GO:0018193 336 0.062
immune response regulating signaling pathway GO:0002764 125 0.060
cellular amino acid metabolic process GO:0006520 103 0.060
aromatic compound catabolic process GO:0019439 286 0.058
nucleotide metabolic process GO:0009117 332 0.056
organonitrogen compound catabolic process GO:1901565 264 0.055
nucleoside phosphate catabolic process GO:1901292 222 0.054
negative regulation of immune system process GO:0002683 209 0.053
maintenance of location GO:0051235 89 0.053
negative regulation of protein metabolic process GO:0051248 282 0.053
muscle tissue development GO:0060537 308 0.053
regulation of cellular amine metabolic process GO:0033238 20 0.053
purine nucleoside triphosphate catabolic process GO:0009146 203 0.052
mapk cascade GO:0000165 281 0.051
negative regulation of phosphorus metabolic process GO:0010563 184 0.050
germ cell development GO:0007281 185 0.050
immune response activating signal transduction GO:0002757 116 0.050
ribose phosphate metabolic process GO:0019693 291 0.050
cellular nitrogen compound catabolic process GO:0044270 280 0.050
regulation of cellular ketone metabolic process GO:0010565 66 0.050
positive regulation of cellular amine metabolic process GO:0033240 5 0.050
regulation of defense response GO:0031347 233 0.050
modification dependent macromolecule catabolic process GO:0043632 133 0.049
striated muscle tissue development GO:0014706 293 0.047
carbohydrate derivative catabolic process GO:1901136 231 0.047
negative regulation of cell proliferation GO:0008285 296 0.046
protein processing GO:0016485 163 0.046
purine ribonucleotide metabolic process GO:0009150 290 0.046
regulation of transferase activity GO:0051338 263 0.045
positive regulation of cellular catabolic process GO:0031331 148 0.045
purine nucleoside metabolic process GO:0042278 241 0.044
ion transmembrane transport GO:0034220 361 0.044
organophosphate catabolic process GO:0046434 232 0.044
cellular lipid metabolic process GO:0044255 323 0.044
cation transport GO:0006812 399 0.044
purine ribonucleoside metabolic process GO:0046128 241 0.043
regulation of kinase activity GO:0043549 249 0.043
nucleotide catabolic process GO:0009166 217 0.042
purine nucleotide metabolic process GO:0006163 302 0.042
activation of immune response GO:0002253 138 0.042
gland development GO:0048732 330 0.042
intracellular protein transport GO:0006886 204 0.041
membrane organization GO:0061024 245 0.041
nucleoside catabolic process GO:0009164 206 0.041
regulation of gtp catabolic process GO:0033124 113 0.041
wnt signaling pathway GO:0016055 188 0.041
purine ribonucleoside catabolic process GO:0046130 205 0.041
macromolecule catabolic process GO:0009057 281 0.040
cellular chemical homeostasis GO:0055082 215 0.040
response to organonitrogen compound GO:0010243 246 0.039
negative regulation of molecular function GO:0044092 258 0.039
positive regulation of protein phosphorylation GO:0001934 242 0.039
ribonucleoside triphosphate catabolic process GO:0009203 199 0.039
chromatin modification GO:0016568 187 0.039
ribonucleoside catabolic process GO:0042454 206 0.039
purine nucleoside triphosphate metabolic process GO:0009144 226 0.039
cation homeostasis GO:0055080 212 0.038
regulation of protein kinase activity GO:0045859 232 0.038
purine containing compound metabolic process GO:0072521 311 0.038
regulation of lymphocyte activation GO:0051249 240 0.038
blood vessel morphogenesis GO:0048514 285 0.038
purine ribonucleotide catabolic process GO:0009154 208 0.038
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.037
inorganic cation transmembrane transport GO:0098662 207 0.037
cellular homeostasis GO:0019725 240 0.037
purine containing compound catabolic process GO:0072523 213 0.037
regulation of cell activation GO:0050865 289 0.037
chemotaxis GO:0006935 247 0.037
digestive system development GO:0055123 200 0.037
axonogenesis GO:0007409 274 0.036
skeletal system development GO:0001501 356 0.036
cellular response to growth factor stimulus GO:0071363 197 0.036
negative regulation of cell activation GO:0050866 111 0.035
positive regulation of cell development GO:0010720 237 0.035
regulation of multi organism process GO:0043900 111 0.035
compound eye development GO:0048749 1 0.035
innate immune response GO:0045087 157 0.035
regulation of cellular amino acid metabolic process GO:0006521 5 0.035
cell fate commitment GO:0045165 210 0.035
regulation of protein localization GO:0032880 231 0.035
gtp metabolic process GO:0046039 144 0.035
guanosine containing compound metabolic process GO:1901068 144 0.034
purine nucleoside catabolic process GO:0006152 205 0.034
negative regulation of phosphate metabolic process GO:0045936 184 0.034
ribonucleoside metabolic process GO:0009119 245 0.034
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.033
regulation of mapk cascade GO:0043408 248 0.033
regulation of nucleotide metabolic process GO:0006140 169 0.033
digestive tract development GO:0048565 190 0.033
regulation of purine nucleotide catabolic process GO:0033121 122 0.032
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.032
positive regulation of cell death GO:0010942 224 0.032
protein maturation GO:0051604 176 0.032
synaptic transmission GO:0007268 329 0.032
developmental growth involved in morphogenesis GO:0060560 138 0.032
regulation of binding GO:0051098 111 0.032
chromatin organization GO:0006325 206 0.032
defense response to bacterium GO:0042742 119 0.031
actin cytoskeleton organization GO:0030036 220 0.031
modification dependent protein catabolic process GO:0019941 133 0.031
oocyte construction GO:0007308 2 0.031
regulation of neuron projection development GO:0010975 169 0.031
lymphocyte differentiation GO:0030098 242 0.031
negative regulation of cellular component organization GO:0051129 194 0.030
muscle cell differentiation GO:0042692 261 0.030
positive regulation of nucleotide metabolic process GO:0045981 114 0.030
regulation of cellular response to stress GO:0080135 159 0.030
gastrulation GO:0007369 116 0.030
regulation of ras protein signal transduction GO:0046578 114 0.030
negative regulation of phosphorylation GO:0042326 166 0.030
regulation of secretion by cell GO:1903530 249 0.030
male gamete generation GO:0048232 285 0.029
regulation of cell projection organization GO:0031344 206 0.029
guanosine containing compound catabolic process GO:1901069 144 0.029
carbohydrate metabolic process GO:0005975 230 0.029
ribonucleoside triphosphate metabolic process GO:0009199 220 0.029
regulation of purine nucleotide metabolic process GO:1900542 169 0.029
regulation of homeostatic process GO:0032844 182 0.029
regulation of cytokine production GO:0001817 266 0.029
cation transmembrane transport GO:0098655 266 0.029
regulation of proteolysis GO:0030162 164 0.029
regionalization GO:0003002 337 0.029
inorganic ion transmembrane transport GO:0098660 234 0.028
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.028
leukocyte proliferation GO:0070661 172 0.028
endocytosis GO:0006897 168 0.028
oocyte axis specification GO:0007309 2 0.028
nucleoside triphosphate metabolic process GO:0009141 230 0.028
cellular macromolecule catabolic process GO:0044265 206 0.027
response to organic cyclic compound GO:0014070 198 0.027
lymphocyte proliferation GO:0046651 164 0.027
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.027
myeloid cell differentiation GO:0030099 233 0.027
regulation of cellular component biogenesis GO:0044087 181 0.027
histone modification GO:0016570 159 0.027
positive regulation of gtp catabolic process GO:0033126 85 0.027
t cell activation GO:0042110 289 0.027
rho protein signal transduction GO:0007266 32 0.027
positive regulation of programmed cell death GO:0043068 218 0.026
regulation of protein transport GO:0051223 163 0.026
t cell differentiation GO:0030217 174 0.026
segmentation GO:0035282 93 0.026
gonad development GO:0008406 141 0.026
regulation of stress activated mapk cascade GO:0032872 69 0.026
peptidyl tyrosine modification GO:0018212 145 0.026
heart morphogenesis GO:0003007 178 0.026
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.026
skeletal muscle organ development GO:0060538 163 0.026
purine nucleotide catabolic process GO:0006195 211 0.025
apoptotic signaling pathway GO:0097190 306 0.025
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.025
t cell proliferation GO:0042098 120 0.025
negative regulation of protein phosphorylation GO:0001933 126 0.025
divalent inorganic cation transport GO:0072511 178 0.025
positive regulation of defense response GO:0031349 124 0.025
protein catabolic process GO:0030163 221 0.025
gtp catabolic process GO:0006184 143 0.025
stress activated protein kinase signaling cascade GO:0031098 81 0.025
regulation of cellular component size GO:0032535 121 0.025
rna processing GO:0006396 105 0.025
glycerolipid metabolic process GO:0046486 122 0.025
reactive oxygen species metabolic process GO:0072593 84 0.025
negative regulation of cellular protein metabolic process GO:0032269 247 0.025
negative regulation of intracellular signal transduction GO:1902532 167 0.025
negative regulation of nervous system development GO:0051961 156 0.025
regulation of cell cycle GO:0051726 281 0.025
positive regulation of transferase activity GO:0051347 167 0.024
microtubule cytoskeleton organization GO:0000226 157 0.024
cell type specific apoptotic process GO:0097285 268 0.024
positive regulation of protein modification process GO:0031401 299 0.024
skeletal system morphogenesis GO:0048705 203 0.024
development of primary sexual characteristics GO:0045137 143 0.024
regulation of t cell activation GO:0050863 170 0.024
ubiquitin dependent protein catabolic process GO:0006511 129 0.024
regulation of establishment of protein localization GO:0070201 181 0.024
formation of primary germ layer GO:0001704 77 0.024
action potential GO:0001508 78 0.024
positive regulation of nervous system development GO:0051962 221 0.024
multicellular organismal signaling GO:0035637 91 0.023
asymmetric stem cell division GO:0098722 3 0.023
skin development GO:0043588 220 0.023
regulation of anatomical structure size GO:0090066 178 0.023
positive regulation of neuron differentiation GO:0045666 141 0.023
metal ion homeostasis GO:0055065 189 0.023
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.023
negative regulation of cellular amine metabolic process GO:0033239 1 0.023
ameboidal type cell migration GO:0001667 128 0.023
positive regulation of kinase activity GO:0033674 155 0.023
protein targeting GO:0006605 143 0.023
protein localization to organelle GO:0033365 185 0.023
sequestering of calcium ion GO:0051208 18 0.023
stress activated mapk cascade GO:0051403 80 0.022
neuron migration GO:0001764 122 0.022
regulation of cell cycle process GO:0010564 160 0.022
epithelial tube morphogenesis GO:0060562 303 0.022
small molecule biosynthetic process GO:0044283 132 0.022
muscle cell development GO:0055001 133 0.022
digestive tract morphogenesis GO:0048546 147 0.022
negative regulation of defense response GO:0031348 77 0.022
sensory perception GO:0007600 245 0.022
myeloid leukocyte differentiation GO:0002573 119 0.022
regulation of transmembrane transport GO:0034762 128 0.022
negative regulation of multi organism process GO:0043901 68 0.022
cellular response to hormone stimulus GO:0032870 150 0.022
protein modification by small protein conjugation GO:0032446 187 0.022
cellular response to organonitrogen compound GO:0071417 145 0.022
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.022
positive regulation of dna templated transcription elongation GO:0032786 2 0.022
regulation of ras gtpase activity GO:0032318 88 0.022
response to growth factor GO:0070848 198 0.022
regulation of membrane potential GO:0042391 192 0.021
multi multicellular organism process GO:0044706 109 0.021
regulation of organelle organization GO:0033043 289 0.021
regulation of protein serine threonine kinase activity GO:0071900 157 0.021
protein acylation GO:0043543 64 0.021
calcium ion transport GO:0006816 159 0.021
interferon beta production GO:0032608 16 0.021
lipid localization GO:0010876 126 0.021
cellular ion homeostasis GO:0006873 165 0.021
response to molecule of bacterial origin GO:0002237 143 0.021
cell growth GO:0016049 130 0.021
stem cell proliferation GO:0072089 117 0.021
negative regulation of hydrolase activity GO:0051346 71 0.021
defense response to virus GO:0051607 68 0.021
epithelial tube formation GO:0072175 130 0.021
adaptive immune response GO:0002250 155 0.021
regulation of lymphocyte proliferation GO:0050670 117 0.020
hindbrain development GO:0030902 128 0.020
positive regulation of mapk cascade GO:0043410 170 0.020
regulation of cell motility GO:2000145 236 0.020
rhythmic process GO:0048511 174 0.020
sequestering of metal ion GO:0051238 19 0.020
response to insulin GO:0032868 100 0.020
nucleoside metabolic process GO:0009116 246 0.020
positive regulation of nucleotide catabolic process GO:0030813 88 0.020
negative regulation of growth GO:0045926 99 0.020
neural precursor cell proliferation GO:0061351 121 0.020
positive regulation of protein kinase activity GO:0045860 144 0.020
negative regulation of cytokine production GO:0001818 84 0.020
cytoplasmic transport GO:0016482 234 0.020
atp metabolic process GO:0046034 75 0.020
leukocyte activation involved in immune response GO:0002366 126 0.020
lipid homeostasis GO:0055088 63 0.020
g protein coupled receptor signaling pathway GO:0007186 243 0.020
tissue remodeling GO:0048771 102 0.020
nucleoside triphosphate catabolic process GO:0009143 205 0.020
anion transmembrane transport GO:0098656 71 0.020
neurotransmitter secretion GO:0007269 62 0.019
response to oxygen levels GO:0070482 62 0.019
positive regulation of apoptotic process GO:0043065 217 0.019
telencephalon development GO:0021537 186 0.019
protein autophosphorylation GO:0046777 61 0.019
positive regulation of interferon alpha production GO:0032727 4 0.019
positive regulation of nucleoside metabolic process GO:0045979 91 0.019
developmental maturation GO:0021700 193 0.019
regulation of rho protein signal transduction GO:0035023 71 0.019
regulation of wnt signaling pathway GO:0030111 123 0.019
cellular protein catabolic process GO:0044257 155 0.019
neural tube formation GO:0001841 108 0.019
regulation of cell migration GO:0030334 219 0.019
morphogenesis of embryonic epithelium GO:0016331 159 0.019
cardiac chamber morphogenesis GO:0003206 93 0.019
regulation of ion transport GO:0043269 215 0.019
regulation of t cell proliferation GO:0042129 92 0.019
placenta development GO:0001890 140 0.019
forebrain development GO:0030900 302 0.019
canonical wnt signaling pathway GO:0060070 130 0.019
regulation of actin cytoskeleton organization GO:0032956 84 0.018
somitogenesis GO:0001756 69 0.018
organelle assembly GO:0070925 177 0.018
neural tube development GO:0021915 160 0.018
positive regulation of protein catabolic process GO:0045732 60 0.018
organelle localization GO:0051640 179 0.018
leukocyte mediated immunity GO:0002443 174 0.018
cellular metal ion homeostasis GO:0006875 151 0.018
respiratory tube development GO:0030323 167 0.018
regulation of protein targeting GO:1903533 61 0.018
lipid storage GO:0019915 36 0.018
regulation of reactive oxygen species metabolic process GO:2000377 40 0.018
regulation of nucleotide catabolic process GO:0030811 122 0.018
dephosphorylation GO:0016311 129 0.018
response to peptide hormone GO:0043434 127 0.018
divalent inorganic cation homeostasis GO:0072507 138 0.018
response to radiation GO:0009314 165 0.018
negative regulation of cell development GO:0010721 169 0.018
epithelial cell proliferation GO:0050673 174 0.018
regulation of leukocyte proliferation GO:0070663 121 0.018
histone acetylation GO:0016573 41 0.017
regulation of cytoskeleton organization GO:0051493 122 0.017
phagocytosis GO:0006909 66 0.017
positive regulation of ras gtpase activity GO:0032320 65 0.017
regulation of system process GO:0044057 200 0.017
asymmetric neuroblast division GO:0055059 1 0.017
hematopoietic progenitor cell differentiation GO:0002244 143 0.017
appendage development GO:0048736 166 0.017
exocytosis GO:0006887 121 0.017
multicellular organismal homeostasis GO:0048871 164 0.017
nucleocytoplasmic transport GO:0006913 139 0.017
b cell activation GO:0042113 161 0.017
metencephalon development GO:0022037 89 0.017
positive regulation of innate immune response GO:0045089 80 0.017
female gamete generation GO:0007292 74 0.017
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.017
regulation of vesicle mediated transport GO:0060627 139 0.017
regulation of protein catabolic process GO:0042176 108 0.017
negative regulation of synapse assembly GO:0051964 3 0.017
cellular response to cytokine stimulus GO:0071345 189 0.017
proteasomal protein catabolic process GO:0010498 98 0.017
divalent metal ion transport GO:0070838 172 0.017
monocarboxylic acid metabolic process GO:0032787 191 0.017
microtubule based process GO:0007017 236 0.017
negative regulation of immune effector process GO:0002698 55 0.017
camera type eye development GO:0043010 266 0.017
negative regulation of homeostatic process GO:0032845 71 0.016
organonitrogen compound biosynthetic process GO:1901566 192 0.016
blastocyst development GO:0001824 80 0.016
fertilization GO:0009566 127 0.016
posttranscriptional regulation of gene expression GO:0010608 155 0.016
negative regulation of protein maturation GO:1903318 79 0.016
transcription from rna polymerase iii promoter GO:0006383 3 0.016
nuclear division GO:0000280 158 0.016
wound healing GO:0042060 157 0.016
multicellular organism growth GO:0035264 161 0.016
tube closure GO:0060606 91 0.016
negative regulation of lymphocyte activation GO:0051250 91 0.016
zygotic determination of anterior posterior axis embryo GO:0007354 3 0.016
lipid biosynthetic process GO:0008610 179 0.016
mitotic cell cycle process GO:1903047 159 0.016
embryonic epithelial tube formation GO:0001838 130 0.016
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.016
stem cell development GO:0048864 219 0.016
interspecies interaction between organisms GO:0044419 83 0.016
establishment or maintenance of cell polarity GO:0007163 86 0.016
synapse organization GO:0050808 125 0.016
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.016
respiratory system development GO:0060541 190 0.016
cellular response to peptide GO:1901653 92 0.016
fatty acid metabolic process GO:0006631 121 0.016
tube formation GO:0035148 140 0.016
calcium ion homeostasis GO:0055074 127 0.016
protein import GO:0017038 101 0.015
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.015
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.015
neuron apoptotic process GO:0051402 142 0.015
peptidyl tyrosine phosphorylation GO:0018108 143 0.015
cell maturation GO:0048469 127 0.015
leukocyte homeostasis GO:0001776 79 0.015
bone development GO:0060348 120 0.015
embryonic skeletal system development GO:0048706 120 0.015
response to transforming growth factor beta GO:0071559 88 0.015
lymphocyte mediated immunity GO:0002449 139 0.015
embryonic placenta development GO:0001892 98 0.015
ossification GO:0001503 216 0.015
protein localization to nucleus GO:0034504 121 0.015
glycerophospholipid metabolic process GO:0006650 71 0.015
peptidyl serine modification GO:0018209 83 0.015
nuclear transport GO:0051169 139 0.015
dendrite development GO:0016358 115 0.015
regulation of protein processing GO:0070613 96 0.015
mitotic cell cycle GO:0000278 195 0.015
macromolecule methylation GO:0043414 120 0.015
sensory organ morphogenesis GO:0090596 242 0.015
response to oxidative stress GO:0006979 123 0.015
response to inorganic substance GO:0010035 96 0.015
regulation of myeloid cell differentiation GO:0045637 96 0.015
organelle fission GO:0048285 170 0.015
organic hydroxy compound metabolic process GO:1901615 203 0.015
positive regulation of immune effector process GO:0002699 107 0.015
cytokine mediated signaling pathway GO:0019221 115 0.015
cell division GO:0051301 120 0.015
regulation of mitotic cell cycle GO:0007346 126 0.015
learning or memory GO:0007611 148 0.015
renal system development GO:0072001 225 0.015
neuron death GO:0070997 154 0.014
regulation of leukocyte differentiation GO:1902105 159 0.014
lateral inhibition GO:0046331 1 0.014
regulation of ral protein signal transduction GO:0032485 4 0.014
blood circulation GO:0008015 195 0.014
response to peptide GO:1901652 136 0.014
anion transport GO:0006820 177 0.014
cell activation involved in immune response GO:0002263 126 0.014
primary neural tube formation GO:0014020 95 0.014
regulation of actin filament based process GO:0032970 99 0.014
neutral lipid metabolic process GO:0006638 57 0.014
localization within membrane GO:0051668 4 0.014
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.014
mesodermal cell migration GO:0008078 4 0.014
protein alkylation GO:0008213 81 0.014
cellular response to lipid GO:0071396 145 0.014
regulation of endopeptidase activity GO:0052548 89 0.014
inflammatory response GO:0006954 244 0.014
regulation of secretion GO:0051046 274 0.014
actin filament organization GO:0007015 113 0.014
nitrogen compound transport GO:0071705 271 0.014
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.014
regulation of protein maturation GO:1903317 96 0.014
striated muscle cell development GO:0055002 125 0.014
glial cell differentiation GO:0010001 131 0.014
spermatogenesis GO:0007283 284 0.014
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.014
negative regulation of proteolysis GO:0045861 74 0.014
nucleoside monophosphate catabolic process GO:0009125 59 0.014
glycerolipid biosynthetic process GO:0045017 50 0.014
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.014
retina development in camera type eye GO:0060041 119 0.014
regulation of jnk cascade GO:0046328 62 0.014
mesoderm development GO:0007498 100 0.014
regulation of nucleoside metabolic process GO:0009118 130 0.014
response to acid chemical GO:0001101 111 0.014
immunoglobulin mediated immune response GO:0016064 69 0.014
cytokine metabolic process GO:0042107 71 0.014
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.014
lung development GO:0030324 164 0.014
myeloid leukocyte activation GO:0002274 83 0.014
organic anion transport GO:0015711 137 0.014
urogenital system development GO:0001655 261 0.014
nucleoside monophosphate metabolic process GO:0009123 85 0.014
oxidation reduction process GO:0055114 342 0.014
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.014
positive regulation of stress activated mapk cascade GO:0032874 48 0.014
cellular response to lipopolysaccharide GO:0071222 77 0.014
locomotory behavior GO:0007626 195 0.013
response to lipopolysaccharide GO:0032496 128 0.013
gliogenesis GO:0042063 141 0.013
regulation of ion transmembrane transport GO:0034765 119 0.013
pallium development GO:0021543 120 0.013
positive regulation of cytokine production GO:0001819 174 0.013
anatomical structure homeostasis GO:0060249 145 0.013
regulation of epithelial cell proliferation GO:0050678 141 0.013
regulation of ion transmembrane transporter activity GO:0032412 54 0.013
embryonic organ morphogenesis GO:0048562 276 0.013
stem cell differentiation GO:0048863 268 0.013
oogenesis GO:0048477 56 0.013
actin filament based movement GO:0030048 23 0.013
myeloid cell homeostasis GO:0002262 114 0.013
response to extracellular stimulus GO:0009991 127 0.013
myotube differentiation GO:0014902 105 0.013
intracellular mrna localization GO:0008298 4 0.013
morphogenesis of a polarized epithelium GO:0001738 37 0.013
negative regulation of apoptotic signaling pathway GO:2001234 104 0.013
lipoprotein metabolic process GO:0042157 43 0.013
regulation of innate immune response GO:0045088 91 0.013
regulation of neurotransmitter levels GO:0001505 87 0.013
regulation of neuron differentiation GO:0045664 281 0.013
appendage morphogenesis GO:0035107 149 0.013
cellular response to dna damage stimulus GO:0006974 207 0.013
triglyceride metabolic process GO:0006641 51 0.013
rna interference GO:0016246 2 0.013
transmission of nerve impulse GO:0019226 76 0.013
rac protein signal transduction GO:0016601 13 0.013
circulatory system process GO:0003013 197 0.013
carbohydrate derivative biosynthetic process GO:1901137 183 0.013
negative regulation of protein modification process GO:0031400 163 0.013
protein ubiquitination GO:0016567 171 0.013
neuronal action potential GO:0019228 54 0.013
regulation of transcription from rna polymerase iii promoter GO:0006359 2 0.013
glucose metabolic process GO:0006006 92 0.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.013

Polg disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.044
nervous system disease DOID:863 0 0.044
immune system disease DOID:2914 0 0.024
central nervous system disease DOID:331 0 0.024
sensory system disease DOID:0050155 0 0.019
eye and adnexa disease DOID:1492 0 0.019
eye disease DOID:5614 0 0.019
cancer DOID:162 0 0.017
disease of cellular proliferation DOID:14566 0 0.017
organ system cancer DOID:0050686 0 0.017
muscular disease DOID:0080000 0 0.016
musculoskeletal system disease DOID:17 0 0.016
retinal disease DOID:5679 0 0.013