Mus musculus

27 known processes

Poli

polymerase (DNA directed), iota

(Aliases: Rad30b)

Poli biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
translesion synthesis GO:0019985 1 0.286
Fly
dna metabolic process GO:0006259 303 0.162
dna repair GO:0006281 107 0.100
Fly
dna recombination GO:0006310 92 0.085
cellular response to dna damage stimulus GO:0006974 207 0.076
Fly
double strand break repair GO:0006302 48 0.064
male meiosis i GO:0007141 16 0.061
response to radiation GO:0009314 165 0.054
regulation of cellular response to stress GO:0080135 159 0.050
regulation of cellular ketone metabolic process GO:0010565 66 0.046
cellular component assembly involved in morphogenesis GO:0010927 139 0.045
dna biosynthetic process GO:0071897 22 0.045
cellular ketone metabolic process GO:0042180 84 0.045
cilium assembly GO:0042384 81 0.045
cellular amino acid metabolic process GO:0006520 103 0.044
amine metabolic process GO:0009308 45 0.038
regulation of cellular amino acid metabolic process GO:0006521 5 0.038
male meiosis GO:0007140 37 0.038
cellular amine metabolic process GO:0044106 44 0.037
regulation of cellular amine metabolic process GO:0033238 20 0.035
double strand break repair via homologous recombination GO:0000724 21 0.035
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.034
positive regulation of cellular amine metabolic process GO:0033240 5 0.033
regulation of double strand break repair via homologous recombination GO:0010569 2 0.032
skeletal system development GO:0001501 356 0.030
meiotic cell cycle process GO:1903046 77 0.029
cilium morphogenesis GO:0060271 102 0.029
cellular nitrogen compound catabolic process GO:0044270 280 0.029
cellular homeostasis GO:0019725 240 0.027
meiotic nuclear division GO:0007126 115 0.026
organelle assembly GO:0070925 177 0.026
spermatogenesis GO:0007283 284 0.026
organic cyclic compound catabolic process GO:1901361 295 0.025
nuclear division GO:0000280 158 0.025
nucleobase containing small molecule metabolic process GO:0055086 352 0.025
response to light stimulus GO:0009416 135 0.024
transmembrane transport GO:0055085 412 0.024
ras protein signal transduction GO:0007265 77 0.024
peptidyl amino acid modification GO:0018193 336 0.024
heterocycle catabolic process GO:0046700 280 0.023
multicellular organismal homeostasis GO:0048871 164 0.023
nitrogen compound transport GO:0071705 271 0.023
carbohydrate metabolic process GO:0005975 230 0.023
regulation of dna recombination GO:0000018 34 0.022
forebrain development GO:0030900 302 0.022
regulation of organelle organization GO:0033043 289 0.021
cation transport GO:0006812 399 0.021
male gamete generation GO:0048232 285 0.021
response to uv GO:0009411 44 0.021
purine containing compound metabolic process GO:0072521 311 0.020
cell type specific apoptotic process GO:0097285 268 0.020
methylation GO:0032259 134 0.020
protein maturation GO:0051604 176 0.020
anatomical structure homeostasis GO:0060249 145 0.020
immune effector process GO:0002252 321 0.020
organelle fission GO:0048285 170 0.020
cellular lipid metabolic process GO:0044255 323 0.019
carbohydrate derivative biosynthetic process GO:1901137 183 0.019
macromolecule methylation GO:0043414 120 0.019
small gtpase mediated signal transduction GO:0007264 97 0.019
regulation of cell activation GO:0050865 289 0.019
meiotic cell cycle GO:0051321 122 0.019
regulation of lymphocyte activation GO:0051249 240 0.019
aromatic compound catabolic process GO:0019439 286 0.018
postreplication repair GO:0006301 5 0.018
Fly
positive regulation of apoptotic process GO:0043065 217 0.018
response to organonitrogen compound GO:0010243 246 0.018
cation transmembrane transport GO:0098655 266 0.018
regulation of membrane potential GO:0042391 192 0.018
positive regulation of cell death GO:0010942 224 0.017
negative regulation of cellular amine metabolic process GO:0033239 1 0.017
synapsis GO:0007129 34 0.017
ion transmembrane transport GO:0034220 361 0.017
organonitrogen compound biosynthetic process GO:1901566 192 0.017
nucleotide metabolic process GO:0009117 332 0.017
smoothened signaling pathway GO:0007224 105 0.017
male sex differentiation GO:0046661 109 0.017
chromosome organization involved in meiosis GO:0070192 39 0.017
macromolecule catabolic process GO:0009057 281 0.017
cellular response to organonitrogen compound GO:0071417 145 0.017
negative regulation of cellular protein metabolic process GO:0032269 247 0.017
cellular response to hormone stimulus GO:0032870 150 0.017
cellular macromolecule catabolic process GO:0044265 206 0.016
nucleoside phosphate metabolic process GO:0006753 338 0.016
positive regulation of protein phosphorylation GO:0001934 242 0.016
chromatin organization GO:0006325 206 0.016
negative regulation of cell proliferation GO:0008285 296 0.016
germ cell development GO:0007281 185 0.016
purine ribonucleotide metabolic process GO:0009150 290 0.016
inorganic cation transmembrane transport GO:0098662 207 0.016
reactive oxygen species metabolic process GO:0072593 84 0.016
lymphocyte differentiation GO:0030098 242 0.016
microtubule based process GO:0007017 236 0.016
cytokine production GO:0001816 319 0.016
sensory perception GO:0007600 245 0.016
t cell activation GO:0042110 289 0.016
protein processing GO:0016485 163 0.016
sensory organ morphogenesis GO:0090596 242 0.016
mitochondrion organization GO:0007005 134 0.016
muscle tissue development GO:0060537 308 0.015
spermatid differentiation GO:0048515 115 0.015
negative regulation of protein metabolic process GO:0051248 282 0.015
regulation of cell projection organization GO:0031344 206 0.015
positive regulation of programmed cell death GO:0043068 218 0.015
oxidation reduction process GO:0055114 342 0.015
negative regulation of cellular component organization GO:0051129 194 0.015
apoptotic signaling pathway GO:0097190 306 0.015
striated muscle tissue development GO:0014706 293 0.015
regulation of homeostatic process GO:0032844 182 0.014
cytoplasmic transport GO:0016482 234 0.014
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.014
nucleoside metabolic process GO:0009116 246 0.014
muscle cell differentiation GO:0042692 261 0.014
connective tissue development GO:0061448 179 0.014
endocytosis GO:0006897 168 0.014
signal transduction involved in mitotic dna damage checkpoint GO:1902402 3 0.014
cellular chemical homeostasis GO:0055082 215 0.014
glycosyl compound metabolic process GO:1901657 246 0.014
maintenance of location GO:0051235 89 0.014
kidney development GO:0001822 213 0.014
renal system development GO:0072001 225 0.014
purine containing compound catabolic process GO:0072523 213 0.014
meiosis i GO:0007127 60 0.014
ribonucleotide metabolic process GO:0009259 291 0.014
mitotic cell cycle GO:0000278 195 0.014
epithelial tube formation GO:0072175 130 0.014
rho protein signal transduction GO:0007266 32 0.014
ribose phosphate metabolic process GO:0019693 291 0.014
purine nucleotide metabolic process GO:0006163 302 0.014
central nervous system neuron differentiation GO:0021953 162 0.014
regulation of secretion GO:0051046 274 0.013
multicellular organismal signaling GO:0035637 91 0.013
glycoprotein metabolic process GO:0009100 116 0.013
metal ion homeostasis GO:0055065 189 0.013
epithelial tube morphogenesis GO:0060562 303 0.013
epithelial cell proliferation GO:0050673 174 0.013
tube formation GO:0035148 140 0.013
regulation of cell motility GO:2000145 236 0.013
posttranscriptional regulation of gene expression GO:0010608 155 0.013
neural tube development GO:0021915 160 0.013
protein ubiquitination GO:0016567 171 0.013
inflammatory response GO:0006954 244 0.013
purine nucleoside catabolic process GO:0006152 205 0.013
ribonucleoside metabolic process GO:0009119 245 0.013
male gonad development GO:0008584 88 0.013
carbohydrate derivative catabolic process GO:1901136 231 0.013
ribonucleoside catabolic process GO:0042454 206 0.013
nucleoside phosphate catabolic process GO:1901292 222 0.013
regulation of response to dna damage stimulus GO:2001020 34 0.013
b cell activation GO:0042113 161 0.013
carbohydrate homeostasis GO:0033500 128 0.013
glucose homeostasis GO:0042593 128 0.013
anion transport GO:0006820 177 0.013
bone development GO:0060348 120 0.013
cellular response to growth factor stimulus GO:0071363 197 0.013
regulation of cellular component biogenesis GO:0044087 181 0.013
microtubule based movement GO:0007018 84 0.013
heart morphogenesis GO:0003007 178 0.013
nucleoside triphosphate metabolic process GO:0009141 230 0.013
lipid biosynthetic process GO:0008610 179 0.013
transmission of nerve impulse GO:0019226 76 0.013
regulation of ion transport GO:0043269 215 0.013
purine ribonucleoside catabolic process GO:0046130 205 0.013
development of primary male sexual characteristics GO:0046546 88 0.013
protein modification by small protein conjugation or removal GO:0070647 207 0.013
positive regulation of hydrolase activity GO:0051345 148 0.013
ossification GO:0001503 216 0.013
divalent inorganic cation transport GO:0072511 178 0.013
monocarboxylic acid metabolic process GO:0032787 191 0.013
organophosphate catabolic process GO:0046434 232 0.013
purine ribonucleoside metabolic process GO:0046128 241 0.013
intraciliary retrograde transport GO:0035721 3 0.013
small molecule biosynthetic process GO:0044283 132 0.012
regulation of hydrolase activity GO:0051336 246 0.012
response to organic cyclic compound GO:0014070 198 0.012
leukocyte mediated immunity GO:0002443 174 0.012
cell activation involved in immune response GO:0002263 126 0.012
inorganic ion transmembrane transport GO:0098660 234 0.012
tissue homeostasis GO:0001894 115 0.012
intrinsic apoptotic signaling pathway GO:0097193 132 0.012
regulation of secretion by cell GO:1903530 249 0.012
cellular response to peptide hormone stimulus GO:0071375 92 0.012
cation homeostasis GO:0055080 212 0.012
response to oxidative stress GO:0006979 123 0.012
cellular response to lipid GO:0071396 145 0.012
fat cell differentiation GO:0045444 160 0.012
regulation of cytokine production GO:0001817 266 0.012
translation GO:0006412 93 0.012
female sex differentiation GO:0046660 84 0.012
regionalization GO:0003002 337 0.012
cellular protein complex assembly GO:0043623 116 0.012
sequestering of calcium ion GO:0051208 18 0.012
neuronal action potential GO:0019228 54 0.012
regulation of anatomical structure size GO:0090066 178 0.012
urogenital system development GO:0001655 261 0.012
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.012
female gonad development GO:0008585 71 0.012
leukocyte differentiation GO:0002521 342 0.012
negative regulation of molecular function GO:0044092 258 0.012
regulation of defense response GO:0031347 233 0.012
myeloid cell differentiation GO:0030099 233 0.012
regulation of proteolysis GO:0030162 164 0.012
purine nucleoside triphosphate catabolic process GO:0009146 203 0.012
macromolecule glycosylation GO:0043413 55 0.012
spermatid development GO:0007286 108 0.012
positive regulation of protein modification process GO:0031401 299 0.012
regulation of cellular catabolic process GO:0031329 242 0.012
nucleoside triphosphate catabolic process GO:0009143 205 0.012
negative regulation of cell development GO:0010721 169 0.012
locomotory behavior GO:0007626 195 0.012
mapk cascade GO:0000165 281 0.012
response to transforming growth factor beta GO:0071559 88 0.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.012
production of molecular mediator of immune response GO:0002440 103 0.012
neuron death GO:0070997 154 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.012
cell adhesion GO:0007155 329 0.012
regulation of protein localization GO:0032880 231 0.012
divalent metal ion transport GO:0070838 172 0.012
regulation of purine nucleotide metabolic process GO:1900542 169 0.012
regulation of mapk cascade GO:0043408 248 0.012
adult behavior GO:0030534 135 0.012
regulation of protein maturation GO:1903317 96 0.012
regulation of hormone levels GO:0010817 211 0.012
skin development GO:0043588 220 0.012
purine nucleotide catabolic process GO:0006195 211 0.011
carboxylic acid biosynthetic process GO:0046394 86 0.011
embryonic organ morphogenesis GO:0048562 276 0.011
protein localization to organelle GO:0033365 185 0.011
limb morphogenesis GO:0035108 149 0.011
hypothalamus gonadotrophin releasing hormone neuron differentiation GO:0021886 4 0.011
sequestering of metal ion GO:0051238 19 0.011
negative regulation of immune system process GO:0002683 209 0.011
telencephalon development GO:0021537 186 0.011
gonad development GO:0008406 141 0.011
intracellular protein transport GO:0006886 204 0.011
morphogenesis of embryonic epithelium GO:0016331 159 0.011
positive regulation of organelle organization GO:0010638 128 0.011
tube closure GO:0060606 91 0.011
camera type eye development GO:0043010 266 0.011
organonitrogen compound catabolic process GO:1901565 264 0.011
cellular response to cytokine stimulus GO:0071345 189 0.011
glycoprotein biosynthetic process GO:0009101 89 0.011
microtubule cytoskeleton organization GO:0000226 157 0.011
purine nucleoside metabolic process GO:0042278 241 0.011
negative regulation of dna replication GO:0008156 4 0.011
nucleotide catabolic process GO:0009166 217 0.011
lymphocyte activation involved in immune response GO:0002285 93 0.011
fertilization GO:0009566 127 0.011
regulation of neuron differentiation GO:0045664 281 0.011
histone modification GO:0016570 159 0.011
ribonucleotide catabolic process GO:0009261 208 0.011
leukocyte proliferation GO:0070661 172 0.011
glycosyl compound catabolic process GO:1901658 206 0.011
divalent inorganic cation homeostasis GO:0072507 138 0.011
g protein coupled receptor signaling pathway GO:0007186 243 0.011
positive regulation of nervous system development GO:0051962 221 0.011
appendage morphogenesis GO:0035107 149 0.011
gland development GO:0048732 330 0.011
regulation of neuron death GO:1901214 134 0.011
organic hydroxy compound metabolic process GO:1901615 203 0.011
ribonucleoside triphosphate catabolic process GO:0009203 199 0.011
protein targeting GO:0006605 143 0.011
response to growth factor GO:0070848 198 0.011
membrane organization GO:0061024 245 0.011
appendage development GO:0048736 166 0.011
positive regulation of cell activation GO:0050867 158 0.011
innate immune response GO:0045087 157 0.011
lymphocyte proliferation GO:0046651 164 0.011
action potential GO:0001508 78 0.011
embryonic epithelial tube formation GO:0001838 130 0.011
blood vessel morphogenesis GO:0048514 285 0.011
asymmetric stem cell division GO:0098722 3 0.010
progesterone metabolic process GO:0042448 4 0.010
blood circulation GO:0008015 195 0.010
rhythmic process GO:0048511 174 0.010
limbic system development GO:0021761 72 0.010
homeostasis of number of cells GO:0048872 210 0.010
regulation of t cell activation GO:0050863 170 0.010
chromatin modification GO:0016568 187 0.010
organic acid biosynthetic process GO:0016053 86 0.010
positive regulation of cell development GO:0010720 237 0.010
regulation of apoptotic signaling pathway GO:2001233 197 0.010
protein modification by small protein conjugation GO:0032446 187 0.010
limb development GO:0060173 166 0.010
cellular carbohydrate metabolic process GO:0044262 119 0.010
endomembrane system organization GO:0010256 147 0.010
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.010
cell substrate adhesion GO:0031589 130 0.010
synaptonemal complex assembly GO:0007130 13 0.010
regulation of multi organism process GO:0043900 111 0.010
cellular alcohol metabolic process GO:0044107 3 0.010
response to peptide GO:1901652 136 0.010
regulation of cell cycle process GO:0010564 160 0.010
regulation of cell cycle GO:0051726 281 0.010
lung development GO:0030324 164 0.010

Poli disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.029
nervous system disease DOID:863 0 0.029
immune system disease DOID:2914 0 0.019
sensory system disease DOID:0050155 0 0.019
eye and adnexa disease DOID:1492 0 0.019
hematopoietic system disease DOID:74 0 0.018
retinal disease DOID:5679 0 0.016
eye disease DOID:5614 0 0.016
musculoskeletal system disease DOID:17 0 0.016
cancer DOID:162 0 0.016
disease of cellular proliferation DOID:14566 0 0.016
disease of metabolism DOID:0014667 0 0.015
connective tissue disease DOID:65 0 0.015
organ system cancer DOID:0050686 0 0.014
inherited metabolic disorder DOID:655 0 0.014
central nervous system disease DOID:331 0 0.012
bone disease DOID:0080001 0 0.012
retinal degeneration DOID:8466 0 0.012
retinitis pigmentosa DOID:10584 0 0.011
anemia DOID:2355 0 0.010