Mus musculus

60 known processes

Krt8

keratin 8

(Aliases: Krt-2.8,MGC118110,Krt2-8,EndoA,AA960620,AL022697,Card2,AU019895,K8)

Krt8 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
intermediate filament cytoskeleton organization GO:0045104 26 0.997
Mouse
keratinocyte differentiation GO:0030216 48 0.924
Mouse
keratinization GO:0031424 9 0.800
Mouse
epidermis development GO:0008544 187 0.773
Mouse
hair follicle morphogenesis GO:0031069 29 0.757
Mouse
tumor necrosis factor mediated signaling pathway GO:0033209 13 0.717
skin morphogenesis GO:0043589 38 0.714
Mouse
cellular response to calcium ion GO:0071277 14 0.676
camera type eye development GO:0043010 266 0.641
epidermis morphogenesis GO:0048730 33 0.633
Mouse
regulation of epidermis development GO:0045682 33 0.613
Mouse
regulation of epidermal cell differentiation GO:0045604 21 0.604
Mouse
skin development GO:0043588 220 0.592
Mouse
extrinsic apoptotic signaling pathway GO:0097191 126 0.584
cytokine mediated signaling pathway GO:0019221 115 0.576
intermediate filament organization GO:0045109 15 0.559
Mouse
hepatocyte apoptotic process GO:0097284 11 0.558
embryonic placenta development GO:0001892 98 0.526
positive regulation of hair follicle development GO:0051798 6 0.520
placenta development GO:0001890 140 0.504
cell adhesion GO:0007155 329 0.483
regulation of water loss via skin GO:0033561 16 0.457
Mouse
protein localization to membrane GO:0072657 108 0.448
regulation of translation GO:0006417 71 0.425
apoptotic signaling pathway GO:0097190 306 0.401
translation GO:0006412 93 0.378
cellular response to inorganic substance GO:0071241 37 0.360
cellular response to cytokine stimulus GO:0071345 189 0.343
intermediate filament based process GO:0045103 27 0.325
Mouse
myeloid dendritic cell chemotaxis GO:0002408 2 0.322
positive regulation of translation GO:0045727 19 0.308
cell type specific apoptotic process GO:0097285 268 0.280
regulation of membrane potential GO:0042391 192 0.270
lens development in camera type eye GO:0002088 62 0.269
positive regulation of epidermis development GO:0045684 13 0.262
positive regulation of hair cycle GO:0042635 7 0.257
establishment of protein localization to plasma membrane GO:0090002 34 0.253
ion transmembrane transport GO:0034220 361 0.246
posttranscriptional regulation of gene expression GO:0010608 155 0.228
cellular response to metal ion GO:0071248 31 0.222
molting cycle GO:0042303 90 0.221
Mouse
response to calcium ion GO:0051592 20 0.220
developmental maturation GO:0021700 193 0.214
regulation of body fluid levels GO:0050878 162 0.213
Mouse
protein localization to plasma membrane GO:0072659 57 0.206
action potential GO:0001508 78 0.204
epithelial cell development GO:0002064 159 0.197
establishment of protein localization to membrane GO:0090150 54 0.196
regulation of cell growth GO:0001558 91 0.190
hair cycle GO:0042633 90 0.187
Mouse
response to inorganic substance GO:0010035 96 0.179
Rat
cell cell adhesion GO:0098609 41 0.179
amine metabolic process GO:0009308 45 0.175
multicellular organismal water homeostasis GO:0050891 23 0.163
Mouse
cell junction organization GO:0034330 77 0.161
wound healing GO:0042060 157 0.158
Zebrafish
single organismal cell cell adhesion GO:0016337 131 0.152
circulatory system process GO:0003013 197 0.147
positive regulation of cell growth GO:0030307 33 0.146
water homeostasis GO:0030104 27 0.144
Mouse
cell growth GO:0016049 130 0.142
calcium independent cell cell adhesion via plasma membrane cell adhesion molecules GO:0016338 4 0.136
establishment of skin barrier GO:0061436 14 0.129
Mouse
transmission of nerve impulse GO:0019226 76 0.121
actin cytoskeleton organization GO:0030036 220 0.111
Rat
striated muscle contraction GO:0006941 45 0.105
cellular component assembly involved in morphogenesis GO:0010927 139 0.100
Rat
regulation of protein localization GO:0032880 231 0.097
cellular amino acid metabolic process GO:0006520 103 0.097
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 40 0.095
transmembrane transport GO:0055085 412 0.095
single organism cell adhesion GO:0098602 156 0.094
membrane organization GO:0061024 245 0.094
cation transport GO:0006812 399 0.094
regulation of hair follicle development GO:0051797 9 0.094
plasma membrane organization GO:0007009 90 0.092
male gamete generation GO:0048232 285 0.092
sensory organ morphogenesis GO:0090596 242 0.091
endomembrane system organization GO:0010256 147 0.089
prostate gland stromal morphogenesis GO:0060741 2 0.089
multicellular organismal signaling GO:0035637 91 0.084
negative regulation of cell development GO:0010721 169 0.084
cellular homeostasis GO:0019725 240 0.083
dendrite development GO:0016358 115 0.082
regulation of neuron differentiation GO:0045664 281 0.078
response to metal ion GO:0010038 47 0.074
ventricular cardiac muscle cell action potential GO:0086005 4 0.074
organelle assembly GO:0070925 177 0.070
Rat
neuronal action potential GO:0019228 54 0.069
dendritic spine morphogenesis GO:0060997 22 0.069
cell maturation GO:0048469 127 0.067
regulation of cytoskeleton organization GO:0051493 122 0.066
muscle cell development GO:0055001 133 0.065
Rat
regulation of system process GO:0044057 200 0.065
leukocyte differentiation GO:0002521 342 0.065
lymphocyte proliferation GO:0046651 164 0.065
neuronal action potential propagation GO:0019227 8 0.064
sensory system development GO:0048880 3 0.064
regulation of establishment of protein localization GO:0070201 181 0.061
ensheathment of neurons GO:0007272 76 0.061
mapk cascade GO:0000165 281 0.059
regulation of defense response GO:0031347 233 0.059
Mouse
protein maturation GO:0051604 176 0.058
positive regulation of mapk cascade GO:0043410 170 0.058
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.058
intracellular protein transport GO:0006886 204 0.057
regulation of secretion GO:0051046 274 0.057
cation homeostasis GO:0055080 212 0.056
cellular amine metabolic process GO:0044106 44 0.055
epithelial cell proliferation GO:0050673 174 0.054
Mouse
blastocyst development GO:0001824 80 0.054
regulation of anatomical structure size GO:0090066 178 0.054
response to organic cyclic compound GO:0014070 198 0.053
hemostasis GO:0007599 78 0.050
cell cell junction organization GO:0045216 72 0.050
regulation of nucleoside metabolic process GO:0009118 130 0.050
regulation of cell projection organization GO:0031344 206 0.050
microtubule based process GO:0007017 236 0.050
tube lumen cavitation GO:0060605 5 0.050
sodium ion export from cell GO:0036376 1 0.049
spermatogenesis GO:0007283 284 0.049
regulation of mapk cascade GO:0043408 248 0.048
epiboly GO:0090504 8 0.047
rho protein signal transduction GO:0007266 32 0.046
regulation of blood circulation GO:1903522 93 0.046
morphogenesis of embryonic epithelium GO:0016331 159 0.046
purine nucleotide catabolic process GO:0006195 211 0.046
regionalization GO:0003002 337 0.045
glycosyl compound catabolic process GO:1901658 206 0.045
heterocycle catabolic process GO:0046700 280 0.044
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.044
inorganic ion transmembrane transport GO:0098660 234 0.044
blood circulation GO:0008015 195 0.043
dna metabolic process GO:0006259 303 0.042
cellular chemical homeostasis GO:0055082 215 0.042
actin filament bundle assembly GO:0051017 40 0.042
gland development GO:0048732 330 0.042
heart process GO:0003015 94 0.042
regulation of cellular amino acid metabolic process GO:0006521 5 0.042
purine nucleoside triphosphate catabolic process GO:0009146 203 0.041
forebrain development GO:0030900 302 0.041
regulation of cellular ketone metabolic process GO:0010565 66 0.041
cardiac muscle cell contraction GO:0086003 7 0.041
ribonucleoside catabolic process GO:0042454 206 0.039
ribonucleoside metabolic process GO:0009119 245 0.038
cell differentiation involved in embryonic placenta development GO:0060706 26 0.038
leukocyte proliferation GO:0070661 172 0.037
guanosine containing compound catabolic process GO:1901069 144 0.037
organic hydroxy compound metabolic process GO:1901615 203 0.037
muscle system process GO:0003012 141 0.037
actin mediated cell contraction GO:0070252 15 0.036
positive regulation of sodium ion export GO:1903275 1 0.036
actin filament based movement GO:0030048 23 0.036
response to tumor necrosis factor GO:0034612 26 0.036
purine ribonucleotide catabolic process GO:0009154 208 0.036
renal sodium excretion GO:0035812 3 0.036
cytoplasmic transport GO:0016482 234 0.035
intrinsic apoptotic signaling pathway GO:0097193 132 0.035
purine containing compound metabolic process GO:0072521 311 0.035
hair follicle development GO:0001942 85 0.035
Mouse
heart contraction GO:0060047 93 0.035
paraxial mesodermal cell differentiation GO:0048342 2 0.035
negative regulation of defense response GO:0031348 77 0.035
Mouse
regulation of epithelial cell proliferation GO:0050678 141 0.034
Mouse
nucleoside catabolic process GO:0009164 206 0.034
negative regulation of cellular component organization GO:0051129 194 0.034
regulation of cellular amine metabolic process GO:0033238 20 0.034
locomotory behavior GO:0007626 195 0.033
inorganic cation transmembrane transport GO:0098662 207 0.033
small gtpase mediated signal transduction GO:0007264 97 0.033
regulation of systemic arterial blood pressure by atrial natriuretic peptide GO:0003050 2 0.033
nucleobase containing small molecule metabolic process GO:0055086 352 0.033
protein processing GO:0016485 163 0.032
cellular response to tumor necrosis factor GO:0071356 21 0.032
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.032
metal ion homeostasis GO:0055065 189 0.032
cellular ketone metabolic process GO:0042180 84 0.032
ear morphogenesis GO:0042471 118 0.032
oocyte axis specification GO:0007309 2 0.032
negative regulation of apoptotic signaling pathway GO:2001234 104 0.032
diacylglycerol biosynthetic process GO:0006651 2 0.031
regulation of neuron projection development GO:0010975 169 0.031
cellular ion homeostasis GO:0006873 165 0.031
embryonic organ morphogenesis GO:0048562 276 0.031
negative regulation of cell activation GO:0050866 111 0.031
synaptic transmission GO:0007268 329 0.031
cation transmembrane transport GO:0098655 266 0.031
positive regulation of ras gtpase activity GO:0032320 65 0.031
fibrinolysis GO:0042730 3 0.030
ribonucleoside triphosphate metabolic process GO:0009199 220 0.030
pole plasm assembly GO:0007315 2 0.029
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.029
regulation of plasminogen activation GO:0010755 4 0.029
digestive tract morphogenesis GO:0048546 147 0.029
ribonucleoside triphosphate catabolic process GO:0009203 199 0.029
regulation of hydrolase activity GO:0051336 246 0.029
cell junction assembly GO:0034329 52 0.028
response to monosaccharide GO:0034284 67 0.028
regulation of organelle organization GO:0033043 289 0.028
chemotaxis GO:0006935 247 0.028
positive regulation of programmed cell death GO:0043068 218 0.028
golgi to plasma membrane protein transport GO:0043001 10 0.028
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.028
regulation of actin cytoskeleton organization GO:0032956 84 0.028
synapse organization GO:0050808 125 0.027
morphogenesis of a branching epithelium GO:0061138 193 0.027
regulation of lymphocyte proliferation GO:0050670 117 0.027
peptidyl amino acid modification GO:0018193 336 0.027
regulation of purine nucleotide catabolic process GO:0033121 122 0.027
regulation of response to wounding GO:1903034 189 0.027
Mouse
granulosa cell differentiation GO:0060014 1 0.027
stem cell development GO:0048864 219 0.027
blood coagulation GO:0007596 76 0.027
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.027
negative regulation of phosphate metabolic process GO:0045936 184 0.027
regulation of heart contraction GO:0008016 77 0.026
regulation of cell adhesion GO:0030155 154 0.026
regulation of gtp catabolic process GO:0033124 113 0.026
actomyosin structure organization GO:0031032 56 0.026
Rat
detection of external stimulus GO:0009581 61 0.025
salivary gland development GO:0007431 37 0.025
regeneration GO:0031099 38 0.025
Zebrafish
regulation of actin filament based process GO:0032970 99 0.025
actin filament organization GO:0007015 113 0.025
activation of immune response GO:0002253 138 0.024
regulation of cellular response to stress GO:0080135 159 0.024
negative regulation of cell proliferation GO:0008285 296 0.024
Mouse
positive regulation of cellular amine metabolic process GO:0033240 5 0.024
striated muscle cell development GO:0055002 125 0.024
Rat
positive regulation of nucleoside metabolic process GO:0045979 91 0.024
cornea development in camera type eye GO:0061303 6 0.024
striated muscle tissue development GO:0014706 293 0.024
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.024
microtubule cytoskeleton organization GO:0000226 157 0.024
axon ensheathment GO:0008366 76 0.024
regulation of cell motility GO:2000145 236 0.024
purine nucleoside metabolic process GO:0042278 241 0.024
av node cell to bundle of his cell communication GO:0086067 2 0.024
digestive system development GO:0055123 200 0.023
cell communication involved in cardiac conduction GO:0086065 9 0.023
neural tube development GO:0021915 160 0.023
cytokine production GO:0001816 319 0.023
response to nutrient levels GO:0031667 109 0.023
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.023
positive regulation of nucleotide catabolic process GO:0030813 88 0.023
regulation of t cell proliferation GO:0042129 92 0.023
muscle tissue development GO:0060537 308 0.023
negative regulation of phosphorylation GO:0042326 166 0.023
nitrogen compound transport GO:0071705 271 0.022
gastrulation GO:0007369 116 0.022
regulation of secretion by cell GO:1903530 249 0.022
golgi vesicle transport GO:0048193 30 0.022
regulation of cellular component biogenesis GO:0044087 181 0.022
guanosine containing compound metabolic process GO:1901068 144 0.022
carbohydrate derivative catabolic process GO:1901136 231 0.022
chromatin organization GO:0006325 206 0.022
axonogenesis GO:0007409 274 0.022
sodium ion transport GO:0006814 73 0.022
nucleoside phosphate catabolic process GO:1901292 222 0.022
oocyte anterior posterior axis specification GO:0007314 2 0.022
positive regulation of cell adhesion GO:0045785 80 0.022
cardiac muscle tissue development GO:0048738 130 0.021
negative regulation of nervous system development GO:0051961 156 0.021
negative regulation of proteolysis GO:0045861 74 0.021
modification dependent protein catabolic process GO:0019941 133 0.021
purine nucleoside catabolic process GO:0006152 205 0.021
muscle cell differentiation GO:0042692 261 0.021
Rat
dephosphorylation GO:0016311 129 0.021
synapse assembly GO:0007416 56 0.021
regulation of hormone levels GO:0010817 211 0.021
aromatic compound catabolic process GO:0019439 286 0.021
compound eye development GO:0048749 1 0.021
myeloid leukocyte migration GO:0097529 57 0.021
ras protein signal transduction GO:0007265 77 0.021
purine ribonucleoside metabolic process GO:0046128 241 0.021
somatic sex determination GO:0018993 2 0.021
lipid biosynthetic process GO:0008610 179 0.021
striated muscle myosin thick filament assembly GO:0071688 1 0.021
liver development GO:0001889 66 0.021
acetate ester transport GO:1901374 2 0.021
paraxial mesodermal cell fate commitment GO:0048343 2 0.020
protein targeting GO:0006605 143 0.020
negative regulation of t cell activation GO:0050868 65 0.020
regulation of transcription from rna polymerase iii promoter GO:0006359 2 0.020
regulation of nucleotide catabolic process GO:0030811 122 0.020
regulation of lymphocyte activation GO:0051249 240 0.020
nephron epithelium development GO:0072009 92 0.020
sodium ion export GO:0071436 2 0.020
extracellular matrix organization GO:0030198 147 0.020
myosin filament assembly GO:0031034 2 0.020
interleukin 8 secretion GO:0072606 3 0.020
organophosphate catabolic process GO:0046434 232 0.019
nucleotide metabolic process GO:0009117 332 0.019
negative regulation of phosphorus metabolic process GO:0010563 184 0.019
cell recognition GO:0008037 83 0.019
nucleoside triphosphate catabolic process GO:0009143 205 0.019
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 18 0.019
endocytosis GO:0006897 168 0.019
positive regulation of cell death GO:0010942 224 0.019
nucleotide catabolic process GO:0009166 217 0.019
oocyte construction GO:0007308 2 0.019
positive regulation of transcription by glucose GO:0046016 3 0.019
hepaticobiliary system development GO:0061008 67 0.019
positive regulation of hydrolase activity GO:0051345 148 0.019
cellular protein complex assembly GO:0043623 116 0.019
ribonucleotide catabolic process GO:0009261 208 0.019
regulation of leukocyte proliferation GO:0070663 121 0.019
negative regulation of dendritic spine development GO:0061000 3 0.019
positive regulation of gene silencing by mirna GO:2000637 1 0.019
regulation of blood pressure GO:0008217 93 0.019
ribose phosphate metabolic process GO:0019693 291 0.019
positive regulation of growth GO:0045927 104 0.019
positive regulation of organelle organization GO:0010638 128 0.018
negative regulation of response to wounding GO:1903035 77 0.018
Mouse
anion transport GO:0006820 177 0.018
glycosyl compound metabolic process GO:1901657 246 0.018
succinate transport GO:0015744 1 0.018
regulation of homeostatic process GO:0032844 182 0.018
muscle contraction GO:0006936 101 0.018
positive regulation of apoptotic process GO:0043065 217 0.018
negative regulation of protein metabolic process GO:0051248 282 0.018
cellular divalent inorganic cation homeostasis GO:0072503 127 0.018
post golgi vesicle mediated transport GO:0006892 13 0.018
regulation of ion transport GO:0043269 215 0.018
transcription from rna polymerase iii promoter GO:0006383 3 0.018
positive regulation of thyroid hormone generation GO:2000611 2 0.018
negative regulation of synapse maturation GO:2000297 2 0.018
nucleoside triphosphate metabolic process GO:0009141 230 0.018
response to oxygen levels GO:0070482 62 0.018
myeloid cell differentiation GO:0030099 233 0.018
cilium morphogenesis GO:0060271 102 0.018
maternal determination of anterior posterior axis embryo GO:0008358 2 0.018
negative regulation of cellular amine metabolic process GO:0033239 1 0.018
positive regulation of cellular catabolic process GO:0031331 148 0.018
i kappab kinase nf kappab signaling GO:0007249 85 0.018
negative regulation of epithelial cell proliferation GO:0050680 64 0.017
Mouse
hematopoietic progenitor cell differentiation GO:0002244 143 0.017
Mouse
response to acid chemical GO:0001101 111 0.017
Rat
positive regulation of cell migration GO:0030335 109 0.017
positive regulation of podosome assembly GO:0071803 3 0.017
viral process GO:0016032 41 0.017
actin polymerization or depolymerization GO:0008154 54 0.017
exocrine system development GO:0035272 45 0.017
purine ribonucleoside catabolic process GO:0046130 205 0.017
response to peptide GO:1901652 136 0.017
positive regulation of protein modification process GO:0031401 299 0.017
tissue regeneration GO:0042246 22 0.017
Zebrafish
ribonucleotide metabolic process GO:0009259 291 0.017
retina development in camera type eye GO:0060041 119 0.017
negative regulation of serine type endopeptidase activity GO:1900004 2 0.017
regulation of endopeptidase activity GO:0052548 89 0.017
regulation of muscle system process GO:0090257 80 0.017
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.017
negative regulation of transcription from rna polymerase ii promoter by glucose GO:0000433 1 0.017
regulation of transferase activity GO:0051338 263 0.017
dendritic spine development GO:0060996 30 0.016
ossification GO:0001503 216 0.016
positive regulation of cellular component biogenesis GO:0044089 94 0.016
regulation of sodium ion export GO:1903273 1 0.016
female sex determination GO:0030237 1 0.016
glomerular mesangial cell differentiation GO:0072008 3 0.016
small molecule biosynthetic process GO:0044283 132 0.016
positive regulation of plasminogen activation GO:0010756 2 0.016
morphogenesis of a branching structure GO:0001763 203 0.016
homeostasis of number of cells GO:0048872 210 0.016
positive regulation of anagen GO:0051885 1 0.016
regulation of cell cycle GO:0051726 281 0.016
regulation of multi organism process GO:0043900 111 0.016
regulation of renal sodium excretion GO:0035813 3 0.016
nucleoside metabolic process GO:0009116 246 0.016
amide transport GO:0042886 138 0.016
insulin metabolic process GO:1901142 3 0.016
purine ribonucleotide metabolic process GO:0009150 290 0.016
regulation of ion transmembrane transport GO:0034765 119 0.016
divalent inorganic cation transport GO:0072511 178 0.016
t cell activation GO:0042110 289 0.016
metanephric capsule development GO:0072213 1 0.016
acetylcholine transport GO:0015870 2 0.016
methylation GO:0032259 134 0.015
organic cyclic compound catabolic process GO:1901361 295 0.015
regulation of protein import into nucleus GO:0042306 52 0.015
digestive tract development GO:0048565 190 0.015
regulation of cell activation GO:0050865 289 0.015
covalent chromatin modification GO:0016569 163 0.015
nk t cell proliferation GO:0001866 2 0.015
regulation of cytokine production GO:0001817 266 0.015
regulation of t cell activation GO:0050863 170 0.015
sensory perception of mechanical stimulus GO:0050954 107 0.015
mesangial cell differentiation GO:0072007 4 0.015
germ cell development GO:0007281 185 0.015
nucleoside phosphate metabolic process GO:0006753 338 0.015
purine nucleotide metabolic process GO:0006163 302 0.015
regulation of protein processing GO:0070613 96 0.015
regulation of proteolysis GO:0030162 164 0.015
regulation of blood vessel size GO:0050880 56 0.015
positive regulation of neuron differentiation GO:0045666 141 0.015
mesoderm morphogenesis GO:0048332 64 0.015
notochord cell development GO:0060035 1 0.015
transepithelial chloride transport GO:0030321 4 0.015
response to organonitrogen compound GO:0010243 246 0.015
positive regulation of t helper 1 cell differentiation GO:0045627 4 0.015
axon guidance GO:0007411 141 0.015
multicellular organismal homeostasis GO:0048871 164 0.015
pyramidal neuron migration GO:0021852 1 0.015
peptide hormone secretion GO:0030072 109 0.014
leukocyte migration GO:0050900 124 0.014
gastrulation with mouth forming second GO:0001702 29 0.014
regulation of nucleotide metabolic process GO:0006140 169 0.014
regulation of organ morphogenesis GO:2000027 144 0.014
renal tubule development GO:0061326 87 0.014
inner ear morphogenesis GO:0042472 101 0.014
cellular response to cadmium ion GO:0071276 3 0.014
positive regulation of mitochondrial calcium ion concentration GO:0051561 3 0.014
cdc42 protein signal transduction GO:0032488 0 0.014
regulation of protein secretion GO:0050708 82 0.014
nephrogenic mesenchyme development GO:0072076 3 0.014
myosin filament organization GO:0031033 3 0.014
epithelium migration GO:0090132 63 0.014
cell cell junction assembly GO:0007043 27 0.014
negative regulation of immune system process GO:0002683 209 0.014
positive regulation of nervous system development GO:0051962 221 0.014
posttranscriptional gene silencing GO:0016441 10 0.014
negative regulation of neuron differentiation GO:0045665 101 0.014
cardiac conduction GO:0061337 17 0.014
regulation of synaptic plasticity GO:0048167 87 0.014
regulation of podosome assembly GO:0071801 3 0.014
renal capsule formation GO:0072129 1 0.014
dendritic cell chemotaxis GO:0002407 7 0.014
positive regulation of gtp catabolic process GO:0033126 85 0.013
regulation of rho protein signal transduction GO:0035023 71 0.013
transition metal ion homeostasis GO:0055076 54 0.013
organic anion transport GO:0015711 137 0.013
regulation of nucleocytoplasmic transport GO:0046822 73 0.013
regulation of cell cycle phase transition GO:1901987 77 0.013
myoblast differentiation involved in skeletal muscle regeneration GO:0014835 3 0.013
cell substrate adhesion GO:0031589 130 0.013
exocytosis GO:0006887 121 0.013
immune effector process GO:0002252 321 0.013
female somatic sex determination GO:0019101 1 0.013
cellular modified amino acid metabolic process GO:0006575 63 0.013
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.013
steroid metabolic process GO:0008202 119 0.013
t cell activation involved in immune response GO:0002286 43 0.013
cellular response to organonitrogen compound GO:0071417 145 0.013
gtp catabolic process GO:0006184 143 0.013
positive regulation of defense response GO:0031349 124 0.013
fasciculation of sensory neuron axon GO:0097155 3 0.013
leukocyte chemotaxis GO:0030595 69 0.013
positive regulation of interleukin 8 production GO:0032757 2 0.013
monosaccharide metabolic process GO:0005996 106 0.013
negative regulation of dendritic spine morphogenesis GO:0061002 3 0.013
gtp metabolic process GO:0046039 144 0.013
mitochondrion organization GO:0007005 134 0.013
peptide hormone processing GO:0016486 9 0.013
regulation of leukocyte differentiation GO:1902105 159 0.013
secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development GO:0060528 4 0.013
response to lipopolysaccharide GO:0032496 128 0.013
regulation of sodium ion transport GO:0002028 29 0.013
cellular nitrogen compound catabolic process GO:0044270 280 0.013
phagocytosis GO:0006909 66 0.013
interspecies interaction between organisms GO:0044419 83 0.013
apical junction assembly GO:0043297 15 0.013
response to light stimulus GO:0009416 135 0.013
neuron projection guidance GO:0097485 141 0.013
desmosome organization GO:0002934 5 0.013
negative regulation of lymphocyte activation GO:0051250 91 0.013
dendrite self avoidance GO:0070593 2 0.013
calcium ion homeostasis GO:0055074 127 0.013
antigen receptor mediated signaling pathway GO:0050851 64 0.013
response to estrogen GO:0043627 24 0.013
cellular response to lipid GO:0071396 145 0.013
mesoderm formation GO:0001707 62 0.013
regulation of protein kinase activity GO:0045859 232 0.013
positive regulation of gtpase activity GO:0043547 85 0.013
cardiac muscle contraction GO:0060048 32 0.013
lung development GO:0030324 164 0.013
regulation of striated muscle contraction GO:0006942 25 0.012

Krt8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
muscular disease DOID:0080000 0 0.324
disease of anatomical entity DOID:7 0 0.324
musculoskeletal system disease DOID:17 0 0.324
myopathy DOID:423 0 0.281
heart disease DOID:114 0 0.281
cardiomyopathy DOID:0050700 0 0.281
cardiovascular system disease DOID:1287 0 0.281
muscle tissue disease DOID:66 0 0.281
intrinsic cardiomyopathy DOID:0060036 0 0.266
arrhythmogenic right ventricular cardiomyopathy DOID:0050431 0 0.266
nervous system disease DOID:863 0 0.051
gastrointestinal system cancer DOID:3119 0 0.019
cancer DOID:162 0 0.019
disease of cellular proliferation DOID:14566 0 0.019
organ system cancer DOID:0050686 0 0.019
sensory system disease DOID:0050155 0 0.014
eye and adnexa disease DOID:1492 0 0.014
eye disease DOID:5614 0 0.014