Mus musculus

0 known processes

Helz

helicase with zinc finger domain

(Aliases: AI851979,3110078M01Rik,KIAA0054,DRHC,9430093I07Rik,9630002H22Rik)

Helz biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
chromatin organization GO:0006325 206 0.254
positive regulation of dna templated transcription elongation GO:0032786 2 0.231
histone acetylation GO:0016573 41 0.174
chromatin modification GO:0016568 187 0.130
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.129
cellular response to dna damage stimulus GO:0006974 207 0.122
covalent chromatin modification GO:0016569 163 0.113
regionalization GO:0003002 337 0.098
cellular macromolecule catabolic process GO:0044265 206 0.078
glycosyl compound catabolic process GO:1901658 206 0.073
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.072
dna metabolic process GO:0006259 303 0.067
peptidyl lysine modification GO:0018205 77 0.062
nucleoside phosphate metabolic process GO:0006753 338 0.059
methylation GO:0032259 134 0.058
purine ribonucleoside metabolic process GO:0046128 241 0.058
histone h3 acetylation GO:0043966 14 0.058
heterocycle catabolic process GO:0046700 280 0.054
nucleotide metabolic process GO:0009117 332 0.051
leukocyte differentiation GO:0002521 342 0.049
compound eye development GO:0048749 1 0.045
wnt signaling pathway GO:0016055 188 0.044
purine nucleoside triphosphate metabolic process GO:0009144 226 0.043
histone modification GO:0016570 159 0.042
cellular amino acid metabolic process GO:0006520 103 0.042
rho protein signal transduction GO:0007266 32 0.042
male gamete generation GO:0048232 285 0.041
lateral inhibition GO:0046331 1 0.041
histone h4 k12 acetylation GO:0043983 2 0.040
regulation of histone methylation GO:0031060 30 0.039
stem cell maintenance GO:0019827 130 0.039
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.038
gonad development GO:0008406 141 0.038
purine nucleoside metabolic process GO:0042278 241 0.037
gene silencing by mirna GO:0035195 10 0.037
macromolecule catabolic process GO:0009057 281 0.037
ribonucleotide catabolic process GO:0009261 208 0.036
ribose phosphate metabolic process GO:0019693 291 0.035
purine ribonucleotide metabolic process GO:0009150 290 0.035
regulation of histone modification GO:0031056 56 0.035
purine containing compound catabolic process GO:0072523 213 0.035
histone lysine methylation GO:0034968 50 0.034
nucleobase containing small molecule metabolic process GO:0055086 352 0.034
nucleotide catabolic process GO:0009166 217 0.034
organic cyclic compound catabolic process GO:1901361 295 0.034
ribonucleoside triphosphate catabolic process GO:0009203 199 0.034
protein acylation GO:0043543 64 0.032
posttranscriptional gene silencing GO:0016441 10 0.032
nucleoside metabolic process GO:0009116 246 0.031
somatic stem cell maintenance GO:0035019 47 0.031
spermatogenesis GO:0007283 284 0.030
male meiosis i GO:0007141 16 0.030
stem cell differentiation GO:0048863 268 0.030
internal peptidyl lysine acetylation GO:0018393 42 0.030
regulation of organelle organization GO:0033043 289 0.030
positive regulation of cellular amine metabolic process GO:0033240 5 0.030
hypermethylation of cpg island GO:0044027 3 0.030
purine containing compound metabolic process GO:0072521 311 0.030
posttranscriptional regulation of gene expression GO:0010608 155 0.029
regulation of dna templated transcription elongation GO:0032784 10 0.029
nucleoside triphosphate metabolic process GO:0009141 230 0.029
blastocyst development GO:0001824 80 0.029
atp metabolic process GO:0046034 75 0.029
ribonucleoside metabolic process GO:0009119 245 0.029
ribonucleoside monophosphate metabolic process GO:0009161 80 0.028
internal protein amino acid acetylation GO:0006475 42 0.028
glycosyl compound metabolic process GO:1901657 246 0.028
cellular nitrogen compound catabolic process GO:0044270 280 0.028
purine ribonucleotide catabolic process GO:0009154 208 0.028
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.028
organonitrogen compound catabolic process GO:1901565 264 0.028
neural precursor cell proliferation GO:0061351 121 0.027
regulation of cell cycle process GO:0010564 160 0.027
regulation of transcription during meiosis GO:0051037 1 0.027
positive regulation of cell death GO:0010942 224 0.027
cellular ketone metabolic process GO:0042180 84 0.027
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.027
regulation of response to dna damage stimulus GO:2001020 34 0.027
amine metabolic process GO:0009308 45 0.027
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.026
peptidyl lysine methylation GO:0018022 29 0.026
peptidyl amino acid modification GO:0018193 336 0.025
blood vessel morphogenesis GO:0048514 285 0.025
ribonucleotide metabolic process GO:0009259 291 0.025
purine ribonucleoside catabolic process GO:0046130 205 0.024
protein modification by small protein conjugation or removal GO:0070647 207 0.023
male meiosis GO:0007140 37 0.023
mrna metabolic process GO:0016071 84 0.023
protein dna complex subunit organization GO:0071824 28 0.023
regulation of cellular amino acid metabolic process GO:0006521 5 0.023
digestive tract morphogenesis GO:0048546 147 0.023
negative regulation of synapse assembly GO:0051964 3 0.023
positive regulation of cellular catabolic process GO:0031331 148 0.023
dna methylation GO:0006306 43 0.023
aromatic compound catabolic process GO:0019439 286 0.023
regulation of nucleotide metabolic process GO:0006140 169 0.023
histone methylation GO:0016571 71 0.023
organophosphate catabolic process GO:0046434 232 0.022
rna interference GO:0016246 2 0.022
lung development GO:0030324 164 0.022
muscle tissue development GO:0060537 308 0.022
regulation of chromatin organization GO:1902275 57 0.022
negative regulation of cellular protein metabolic process GO:0032269 247 0.021
macromolecule methylation GO:0043414 120 0.021
negative regulation of cell development GO:0010721 169 0.021
dna repair GO:0006281 107 0.021
negative regulation of cell proliferation GO:0008285 296 0.021
endocytosis GO:0006897 168 0.020
stem cell development GO:0048864 219 0.020
notch signaling pathway GO:0007219 71 0.020
germ cell development GO:0007281 185 0.020
regulation of cellular catabolic process GO:0031329 242 0.020
negative regulation of cellular component organization GO:0051129 194 0.020
purine nucleoside catabolic process GO:0006152 205 0.019
rna processing GO:0006396 105 0.019
regulation of cell cycle GO:0051726 281 0.019
Mouse
myeloid cell differentiation GO:0030099 233 0.019
rhythmic process GO:0048511 174 0.019
small gtpase mediated signal transduction GO:0007264 97 0.019
embryonic organ morphogenesis GO:0048562 276 0.019
positive regulation of apoptotic process GO:0043065 217 0.019
purine nucleotide catabolic process GO:0006195 211 0.019
protein catabolic process GO:0030163 221 0.019
purine nucleoside monophosphate metabolic process GO:0009126 81 0.019
cellular amine metabolic process GO:0044106 44 0.019
regulation of cellular response to stress GO:0080135 159 0.019
neuroblast fate commitment GO:0014017 1 0.018
segmentation GO:0035282 93 0.018
mitotic cell cycle process GO:1903047 159 0.018
regulation of neuron differentiation GO:0045664 281 0.018
nucleoside phosphate catabolic process GO:1901292 222 0.018
protein alkylation GO:0008213 81 0.018
ribonucleoside triphosphate metabolic process GO:0009199 220 0.018
regulation of neuron death GO:1901214 134 0.018
cellular protein catabolic process GO:0044257 155 0.018
ribonucleoside monophosphate catabolic process GO:0009158 57 0.018
nucleoside catabolic process GO:0009164 206 0.018
neuroblast differentiation GO:0014016 2 0.018
positive regulation of nucleoside metabolic process GO:0045979 91 0.018
regulation of defense response GO:0031347 233 0.018
canonical wnt signaling pathway GO:0060070 130 0.018
purine nucleoside monophosphate catabolic process GO:0009128 58 0.018
regulation of mitotic cell cycle GO:0007346 126 0.018
negative regulation of protein metabolic process GO:0051248 282 0.018
regulation of cellular amine metabolic process GO:0033238 20 0.018
sensory perception GO:0007600 245 0.017
regulation of cell projection organization GO:0031344 206 0.017
histone h4 acetylation GO:0043967 10 0.017
nuclear division GO:0000280 158 0.017
purine nucleoside triphosphate catabolic process GO:0009146 203 0.017
striated muscle tissue development GO:0014706 293 0.017
peptidyl lysine trimethylation GO:0018023 12 0.017
axon guidance GO:0007411 141 0.017
telencephalon development GO:0021537 186 0.017
chemotaxis GO:0006935 247 0.017
histone h3 k4 trimethylation GO:0080182 5 0.017
peptidyl lysine acetylation GO:0018394 45 0.017
cell cycle checkpoint GO:0000075 47 0.017
histone h4 k16 acetylation GO:0043984 3 0.017
neuron projection guidance GO:0097485 141 0.017
microtubule based process GO:0007017 236 0.016
organophosphate biosynthetic process GO:0090407 122 0.016
gene silencing by rna GO:0031047 19 0.016
purine nucleotide metabolic process GO:0006163 302 0.016
alpha beta t cell activation GO:0046631 91 0.016
regulation of purine nucleotide catabolic process GO:0033121 122 0.016
protein methylation GO:0006479 81 0.016
histone deubiquitination GO:0016578 2 0.016
body morphogenesis GO:0010171 45 0.016
gene silencing GO:0016458 38 0.016
regulation of gtp catabolic process GO:0033124 113 0.016
positive regulation of programmed cell death GO:0043068 218 0.016
mesenchyme development GO:0060485 152 0.016
organelle localization GO:0051640 179 0.016
carbohydrate derivative catabolic process GO:1901136 231 0.016
protein modification by small protein conjugation GO:0032446 187 0.016
renal system development GO:0072001 225 0.016
t cell activation GO:0042110 289 0.015
carbohydrate metabolic process GO:0005975 230 0.015
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.015
lymphocyte differentiation GO:0030098 242 0.015
neuromuscular process GO:0050905 99 0.015
forebrain development GO:0030900 302 0.015
heart morphogenesis GO:0003007 178 0.015
sensory perception of mechanical stimulus GO:0050954 107 0.015
morphogenesis of embryonic epithelium GO:0016331 159 0.015
locomotory behavior GO:0007626 195 0.015
nucleoside monophosphate metabolic process GO:0009123 85 0.015
digestive tract development GO:0048565 190 0.015
regulation of cellular ketone metabolic process GO:0010565 66 0.015
embryonic placenta development GO:0001892 98 0.014
transcription elongation from rna polymerase ii promoter GO:0006368 9 0.014
axonogenesis GO:0007409 274 0.014
camera type eye development GO:0043010 266 0.014
ear development GO:0043583 200 0.014
chromatin remodeling GO:0006338 32 0.014
regulation of nucleoside metabolic process GO:0009118 130 0.014
skeletal system development GO:0001501 356 0.014
cell recognition GO:0008037 83 0.014
cell type specific apoptotic process GO:0097285 268 0.014
maintenance of location GO:0051235 89 0.014
positive regulation of histone h3 k9 methylation GO:0051574 4 0.014
microtubule cytoskeleton organization GO:0000226 157 0.014
stem cell fate specification GO:0048866 3 0.014
anatomical structure homeostasis GO:0060249 145 0.014
asymmetric stem cell division GO:0098722 3 0.013
positive regulation of nervous system development GO:0051962 221 0.013
digestive system development GO:0055123 200 0.013
negative regulation of organelle organization GO:0010639 90 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.013
organelle assembly GO:0070925 177 0.013
skeletal muscle organ development GO:0060538 163 0.013
intracellular receptor signaling pathway GO:0030522 74 0.013
cytokine production GO:0001816 319 0.013
respiratory tube development GO:0030323 167 0.013
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.013
cytoplasmic transport GO:0016482 234 0.013
regulation of mitotic cell cycle phase transition GO:1901990 73 0.013
neuronal action potential GO:0019228 54 0.013
gastrulation GO:0007369 116 0.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.013
modification dependent macromolecule catabolic process GO:0043632 133 0.013
posttranscriptional gene silencing by rna GO:0035194 10 0.013
mitotic cell cycle GO:0000278 195 0.013
regulation of chromosome organization GO:0033044 83 0.013
skeletal muscle cell differentiation GO:0035914 66 0.012
b cell activation GO:0042113 161 0.012
development of primary sexual characteristics GO:0045137 143 0.012
neural tube formation GO:0001841 108 0.012
ribonucleoside catabolic process GO:0042454 206 0.012
regulation of response to drug GO:2001023 2 0.012
dna modification GO:0006304 50 0.012
epithelial cell development GO:0002064 159 0.012
artery development GO:0060840 53 0.012
pharynx development GO:0060465 1 0.012
ras protein signal transduction GO:0007265 77 0.012
regulation of anatomical structure size GO:0090066 178 0.012
lipid localization GO:0010876 126 0.012
mesenchymal cell differentiation GO:0048762 107 0.012
nucleoside triphosphate catabolic process GO:0009143 205 0.012
response to growth factor GO:0070848 198 0.012
t cell differentiation GO:0030217 174 0.012
female sex differentiation GO:0046660 84 0.012
morphogenesis of a branching structure GO:0001763 203 0.012
actin cytoskeleton organization GO:0030036 220 0.012
histone h3 k4 methylation GO:0051568 23 0.012
positive regulation of protein modification process GO:0031401 299 0.012
regulation of wnt signaling pathway GO:0030111 123 0.012
regulation of cell motility GO:2000145 236 0.012
proteasomal protein catabolic process GO:0010498 98 0.012
negative regulation of cell cycle GO:0045786 123 0.012
Mouse
regulation of rho gtpase activity GO:0032319 58 0.012
mrna catabolic process GO:0006402 22 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.011
regulation of membrane potential GO:0042391 192 0.011
neuron apoptotic process GO:0051402 142 0.011
positive regulation of protein phosphorylation GO:0001934 242 0.011
somite development GO:0061053 81 0.011
myosin filament assembly GO:0031034 2 0.011
myeloid cell homeostasis GO:0002262 114 0.011
regulation of notch signaling pathway GO:0008593 35 0.011
neuromuscular process controlling balance GO:0050885 59 0.011
cellular lipid metabolic process GO:0044255 323 0.011
negative regulation of cell cycle process GO:0010948 69 0.011
endodermal cell fate specification GO:0001714 4 0.011
positive regulation of neuron differentiation GO:0045666 141 0.011
cell fate commitment GO:0045165 210 0.011
regulation of cellular component size GO:0032535 121 0.011
regulation of asymmetric cell division GO:0009786 4 0.011
sensory system development GO:0048880 3 0.011
positive regulation of rho gtpase activity GO:0032321 41 0.011
sensory organ morphogenesis GO:0090596 242 0.011
urogenital system development GO:0001655 261 0.011
female gamete generation GO:0007292 74 0.011
negative regulation of nervous system development GO:0051961 156 0.011
morphogenesis of a branching epithelium GO:0061138 193 0.011
regulation of neuron apoptotic process GO:0043523 122 0.011
organonitrogen compound biosynthetic process GO:1901566 192 0.011
histone h3 k14 acetylation GO:0044154 3 0.011
regulation of neuron projection development GO:0010975 169 0.011
branching morphogenesis of an epithelial tube GO:0048754 159 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.011
glucose homeostasis GO:0042593 128 0.011
vagus nerve development GO:0021564 3 0.011
regulation of bmp signaling pathway GO:0030510 60 0.010
positive regulation of nucleotide metabolic process GO:0045981 114 0.010
regulation of purine nucleotide metabolic process GO:1900542 169 0.010
cellular response to growth factor stimulus GO:0071363 197 0.010
dna templated transcription elongation GO:0006354 13 0.010
neuron death GO:0070997 154 0.010
mitotic cytokinesis GO:0000281 4 0.010
carbohydrate homeostasis GO:0033500 128 0.010
regulation of chromatin silencing GO:0031935 2 0.010
placenta development GO:0001890 140 0.010
myotube differentiation GO:0014902 105 0.010
protein ubiquitination GO:0016567 171 0.010
nucleocytoplasmic transport GO:0006913 139 0.010
negative regulation of intracellular signal transduction GO:1902532 167 0.010

Helz disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.019
disease of cellular proliferation DOID:14566 0 0.019
organ system cancer DOID:0050686 0 0.019
disease of anatomical entity DOID:7 0 0.015
musculoskeletal system disease DOID:17 0 0.015
connective tissue disease DOID:65 0 0.015