|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.977
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.920
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.830
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.793
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.760
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.728
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.667
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.642
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.621
|
|
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.608
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.608
|
Mouse |
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.602
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.561
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.534
|
|
|
|
cytokine secretion
|
GO:0050663 |
72 |
0.533
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.520
|
Human |
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.507
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.493
|
Mouse |
|
|
positive regulation of macrophage chemotaxis
|
GO:0010759 |
5 |
0.479
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.437
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.434
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.432
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.428
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.424
|
|
|
|
positive regulation of cytokine secretion
|
GO:0050715 |
41 |
0.424
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.422
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.409
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.403
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.400
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.375
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
82 |
0.374
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.373
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.361
|
Mouse |
|
|
granulocyte migration
|
GO:0097530 |
43 |
0.361
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.352
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.350
|
|
|
|
purinergic nucleotide receptor signaling pathway
|
GO:0035590 |
3 |
0.350
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
69 |
0.341
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.341
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
73 |
0.338
|
|
|
|
positive regulation of neutrophil chemotaxis
|
GO:0090023 |
12 |
0.322
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.322
|
Mouse |
|
|
t cell activation
|
GO:0042110 |
289 |
0.320
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.312
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.307
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.305
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.296
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.288
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.285
|
Mouse |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.284
|
|
|
|
positive regulation of protein secretion
|
GO:0050714 |
52 |
0.271
|
|
|
|
regulation of cytokine secretion
|
GO:0050707 |
61 |
0.269
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.267
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
47 |
0.265
|
Mouse |
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.259
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.255
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.249
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.248
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.246
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.245
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.240
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.237
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.235
|
Mouse |
|
|
regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903555 |
50 |
0.234
|
|
|
|
positive regulation of cytokine biosynthetic process
|
GO:0042108 |
40 |
0.232
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.231
|
Mouse |
|
|
adenylate cyclase modulating g protein coupled receptor signaling pathway
|
GO:0007188 |
54 |
0.229
|
|
|
|
kidney development
|
GO:0001822 |
213 |
0.229
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.227
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.215
|
|
|
|
positive regulation of monocyte chemotaxis
|
GO:0090026 |
2 |
0.213
|
|
|
|
neuron migration
|
GO:0001764 |
122 |
0.212
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.212
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.206
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.206
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.206
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.199
|
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
59 |
0.198
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.192
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.192
|
Mouse |
|
|
learning or memory
|
GO:0007611 |
148 |
0.192
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.191
|
|
|
|
positive regulation of adaptive immune response
|
GO:0002821 |
61 |
0.189
|
|
|
|
innate immune response activating signal transduction
|
GO:0002758 |
50 |
0.189
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
64 |
0.187
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.187
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.186
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.185
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.185
|
Mouse |
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.183
|
|
|
|
helper t cell chemotaxis
|
GO:0035704 |
1 |
0.181
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.180
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
19 |
0.180
|
|
|
|
cytokine metabolic process
|
GO:0042107 |
71 |
0.179
|
|
|
|
regulation of b cell activation
|
GO:0050864 |
81 |
0.178
|
|
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.178
|
|
|
|
granulocyte chemotaxis
|
GO:0071621 |
39 |
0.177
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.176
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.176
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.176
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.174
|
|
|
|
defense response to virus
|
GO:0051607 |
68 |
0.173
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.173
|
|
|
|
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger
|
GO:0007187 |
55 |
0.171
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
70 |
0.171
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.170
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.169
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.169
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.167
|
Mouse |
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.166
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.166
|
|
|
|
humoral immune response
|
GO:0006959 |
57 |
0.164
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.163
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.159
|
|
|
|
antigen processing and presentation
|
GO:0019882 |
47 |
0.158
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
61 |
0.158
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.158
|
|
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
49 |
0.157
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.157
|
|
|
|
calcium mediated signaling
|
GO:0019722 |
46 |
0.156
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.153
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
93 |
0.153
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.153
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.152
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.152
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.151
|
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.151
|
|
|
|
positive regulation of t cell extravasation
|
GO:2000409 |
2 |
0.151
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.150
|
|
|
|
regulation of neutrophil chemotaxis
|
GO:0090022 |
14 |
0.149
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.148
|
Mouse |
|
|
negative regulation of cytokine production
|
GO:0001818 |
84 |
0.147
|
|
|
|
protein secretion
|
GO:0009306 |
111 |
0.146
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.144
|
|
|
|
interferon beta biosynthetic process
|
GO:0045350 |
4 |
0.143
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.142
|
Mouse |
|
|
negative regulation of adaptive immune response
|
GO:0002820 |
25 |
0.140
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.140
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.140
|
Mouse |
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.140
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.138
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.137
|
|
|
|
regulation of phospholipase c activity
|
GO:1900274 |
3 |
0.136
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.136
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.134
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.130
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.129
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.129
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.128
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.126
|
Mouse |
|
|
positive regulation of chemotaxis
|
GO:0050921 |
38 |
0.125
|
|
|
|
t helper 17 cell chemotaxis
|
GO:0035705 |
1 |
0.125
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.124
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.123
|
Mouse |
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.121
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.120
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.120
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
70 |
0.119
|
|
|
|
positive regulation of phospholipase activity
|
GO:0010518 |
3 |
0.118
|
|
|
|
positive regulation of homeostatic process
|
GO:0032846 |
64 |
0.117
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.116
|
|
|
|
positive regulation of camp mediated signaling
|
GO:0043950 |
3 |
0.115
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.114
|
Mouse |
|
|
cytosolic calcium ion transport
|
GO:0060401 |
48 |
0.113
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.113
|
|
|
|
positive regulation of neutrophil migration
|
GO:1902624 |
12 |
0.113
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.112
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.111
|
Mouse |
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.111
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.110
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.110
|
|
|
|
negative regulation of leukocyte mediated immunity
|
GO:0002704 |
29 |
0.109
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.108
|
Mouse |
|
|
protein targeting
|
GO:0006605 |
143 |
0.108
|
|
|
|
regulation of acute inflammatory response
|
GO:0002673 |
27 |
0.106
|
|
|
|
positive regulation of t cell receptor signaling pathway
|
GO:0050862 |
4 |
0.106
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.105
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
69 |
0.105
|
|
|
|
regulation of monocyte chemotaxis
|
GO:0090025 |
3 |
0.104
|
|
|
|
release of sequestered calcium ion into cytosol
|
GO:0051209 |
42 |
0.103
|
|
|
|
positive regulation of monocyte extravasation
|
GO:2000439 |
1 |
0.103
|
|
|
|
defense response to gram positive bacterium
|
GO:0050830 |
50 |
0.103
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.103
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.103
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
65 |
0.103
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.101
|
|
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.101
|
|
|
|
positive regulation of behavior
|
GO:0048520 |
40 |
0.100
|
|
|
|
neutrophil migration
|
GO:1990266 |
37 |
0.100
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.100
|
|
|
|
toll like receptor 7 signaling pathway
|
GO:0034154 |
4 |
0.100
|
|
|
|
tumor necrosis factor superfamily cytokine production
|
GO:0071706 |
51 |
0.099
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.098
|
|
|
|
t cell activation involved in immune response
|
GO:0002286 |
43 |
0.098
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
71 |
0.097
|
Mouse |
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.096
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.096
|
|
|
|
negative regulation of immune effector process
|
GO:0002698 |
55 |
0.095
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.095
|
Mouse |
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.095
|
|
|
|
positive regulation of phospholipase c activity
|
GO:0010863 |
2 |
0.095
|
|
|
|
negative regulation of synapse assembly
|
GO:0051964 |
3 |
0.095
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.092
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.091
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.090
|
Mouse |
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.090
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.089
|
|
|
|
positive regulation of tumor necrosis factor biosynthetic process
|
GO:0042535 |
8 |
0.089
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.088
|
Mouse |
|
|
ossification
|
GO:0001503 |
216 |
0.088
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.087
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
71 |
0.087
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.087
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.086
|
|
|
|
b cell homeostasis
|
GO:0001782 |
34 |
0.085
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.085
|
|
|
|
memory
|
GO:0007613 |
58 |
0.085
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.084
|
|
|
|
regulation of g protein coupled receptor protein signaling pathway
|
GO:0008277 |
37 |
0.084
|
|
|
|
regulated secretory pathway
|
GO:0045055 |
32 |
0.084
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.084
|
Mouse |
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.083
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.083
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
84 |
0.083
|
|
|
|
regulation of toll like receptor 9 signaling pathway
|
GO:0034163 |
3 |
0.082
|
|
|
|
adenylate cyclase activating g protein coupled receptor signaling pathway
|
GO:0007189 |
30 |
0.082
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.082
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.082
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.081
|
|
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
47 |
0.081
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.081
|
|
|
|
t cell receptor signaling pathway
|
GO:0050852 |
46 |
0.081
|
|
|
|
single organism nuclear import
|
GO:1902593 |
95 |
0.080
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.080
|
|
|
|
regulation of cyclic nucleotide metabolic process
|
GO:0030799 |
40 |
0.079
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.079
|
|
|
|
negative regulation of t cell proliferation
|
GO:0042130 |
38 |
0.079
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
61 |
0.079
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.079
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.077
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
18 |
0.077
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.077
|
Mouse |
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.077
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.077
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.077
|
Mouse |
|
|
cell surface pattern recognition receptor signaling pathway
|
GO:0002752 |
2 |
0.076
|
|
|
|
positive regulation of immunological synapse formation
|
GO:2000522 |
1 |
0.076
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.076
|
|
|
|
blood circulation
|
GO:0008015 |
195 |
0.076
|
Mouse |
|
|
muscle system process
|
GO:0003012 |
141 |
0.075
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.075
|
|
|
|
extracellular matrix organization
|
GO:0030198 |
147 |
0.075
|
Mouse |
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.075
|
|
|
|
positive regulation of leukocyte mediated immunity
|
GO:0002705 |
70 |
0.075
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
106 |
0.074
|
|
|
|
renal system development
|
GO:0072001 |
225 |
0.074
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
2 |
0.074
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.074
|
|
|
|
myeloid leukocyte mediated immunity
|
GO:0002444 |
42 |
0.073
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
8 |
0.072
|
|
|
|
cyclic nucleotide metabolic process
|
GO:0009187 |
59 |
0.072
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.072
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.071
|
|
|
|
regulation of ossification
|
GO:0030278 |
112 |
0.071
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.071
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
74 |
0.071
|
Mouse |
|
|
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002824 |
61 |
0.070
|
|
|
|
extracellular structure organization
|
GO:0043062 |
148 |
0.070
|
Mouse |
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.070
|
|
|
|
regulation of interferon gamma production
|
GO:0032649 |
57 |
0.070
|
|
|
|
regulation of cd8 positive alpha beta t cell activation
|
GO:2001185 |
3 |
0.070
|
|
|
|
regulation of phagocytosis
|
GO:0050764 |
33 |
0.069
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.069
|
|
|
|
positive regulation of nucleotide biosynthetic process
|
GO:0030810 |
26 |
0.068
|
|
|
|
positive regulation of granulocyte macrophage colony stimulating factor biosynthetic process
|
GO:0045425 |
2 |
0.068
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.067
|
|
|
|
negative regulation of hypersensitivity
|
GO:0002884 |
3 |
0.067
|
|
|
|
thymocyte migration
|
GO:0072679 |
2 |
0.066
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.066
|
|
|
|
positive regulation of cd8 positive alpha beta t cell extravasation
|
GO:2000451 |
2 |
0.066
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.065
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
55 |
0.065
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.065
|
|
|
|
cd8 positive alpha beta t cell extravasation
|
GO:0035697 |
3 |
0.064
|
|
|
|
nucleotide biosynthetic process
|
GO:0009165 |
78 |
0.064
|
|
|
|
regulation of leukocyte mediated cytotoxicity
|
GO:0001910 |
38 |
0.064
|
|
|
|
regulation of t cell costimulation
|
GO:2000523 |
2 |
0.064
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.064
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.064
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
116 |
0.063
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.063
|
|
|
|
interleukin 2 production
|
GO:0032623 |
33 |
0.063
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.063
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.063
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.063
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.063
|
|
|
|
regulation of immunological synapse formation
|
GO:2000520 |
2 |
0.063
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.063
|
Mouse |
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.063
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.063
|
Mouse |
|
|
positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation
|
GO:2000526 |
1 |
0.062
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.062
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.062
|
|
|
|
microglia differentiation
|
GO:0014004 |
2 |
0.062
|
|
|
|
activation of innate immune response
|
GO:0002218 |
56 |
0.061
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.061
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.061
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.061
|
|
|
|
activation of mapk activity
|
GO:0000187 |
59 |
0.061
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.060
|
|
|
|
regulation of muscle system process
|
GO:0090257 |
80 |
0.060
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.059
|
|
|
|
positive regulation of hematopoietic stem cell migration
|
GO:2000473 |
1 |
0.059
|
|
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.059
|
|
|
|
positive regulation of camp metabolic process
|
GO:0030816 |
19 |
0.058
|
|
|
|
regulation of antigen receptor mediated signaling pathway
|
GO:0050854 |
29 |
0.058
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.057
|
|
|
|
positive regulation of dendritic cell chemotaxis
|
GO:2000510 |
1 |
0.057
|
|
|
|
camp mediated signaling
|
GO:0019933 |
15 |
0.057
|
|
|
|
negative regulation of eosinophil degranulation
|
GO:0043310 |
1 |
0.057
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.056
|
|
|
|
positive regulation of inflammatory response
|
GO:0050729 |
47 |
0.056
|
|
|
|
cell killing
|
GO:0001906 |
67 |
0.056
|
|
|
|
smooth muscle contraction
|
GO:0006939 |
44 |
0.056
|
|
|
|
actin filament organization
|
GO:0007015 |
113 |
0.055
|
|
|
|
tumor necrosis factor biosynthetic process
|
GO:0042533 |
10 |
0.055
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.055
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.055
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
122 |
0.055
|
|
|
|
cd4 positive alpha beta t cell differentiation
|
GO:0043367 |
41 |
0.054
|
|
|
|
negative regulation of t cell activation
|
GO:0050868 |
65 |
0.053
|
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
55 |
0.053
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.053
|
|
|
|
myeloid leukocyte migration
|
GO:0097529 |
57 |
0.053
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.053
|
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.052
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
0 |
0.052
|
|
|
|
phagocytosis
|
GO:0006909 |
66 |
0.052
|
|
|
|
cellular response to prostaglandin d stimulus
|
GO:0071799 |
1 |
0.052
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.052
|
|
|
|
positive regulation of response to wounding
|
GO:1903036 |
66 |
0.052
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.052
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.051
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.051
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
80 |
0.051
|
Mouse |
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.051
|
|
|
|
dendritic spine maintenance
|
GO:0097062 |
4 |
0.050
|
|
|
|
tissue remodeling
|
GO:0048771 |
102 |
0.050
|
Mouse |
|
|
organic hydroxy compound transport
|
GO:0015850 |
93 |
0.050
|
|
|
|
regulation of dendritic cell chemotaxis
|
GO:2000508 |
1 |
0.050
|
|
|
|
hypersensitivity
|
GO:0002524 |
10 |
0.050
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
143 |
0.050
|
|
|
|
fc receptor mediated inhibitory signaling pathway
|
GO:0002774 |
1 |
0.049
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.049
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.049
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.049
|
|
|
|
detection of bacterium
|
GO:0016045 |
7 |
0.049
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.049
|
|
|
|
microglial cell activation involved in immune response
|
GO:0002282 |
1 |
0.049
|
|
|
|
antigen processing and presentation of peptide antigen
|
GO:0048002 |
29 |
0.049
|
|
|
|
acute inflammatory response
|
GO:0002526 |
41 |
0.048
|
|
|
|
regulation of camp metabolic process
|
GO:0030814 |
30 |
0.048
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.047
|
|
|
|
regulation of neutrophil migration
|
GO:1902622 |
14 |
0.047
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.047
|
Mouse |
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
82 |
0.047
|
|
|
|
b cell mediated immunity
|
GO:0019724 |
71 |
0.046
|
|
|
|
protein import
|
GO:0017038 |
101 |
0.046
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
81 |
0.046
|
|
|
|
cellularization
|
GO:0007349 |
1 |
0.046
|
|
|
|
regulation of chemokine production
|
GO:0032642 |
30 |
0.046
|
|
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
41 |
0.046
|
|
|
|
synapse organization
|
GO:0050808 |
125 |
0.046
|
|
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
56 |
0.046
|
|
|
|
eosinophil activation
|
GO:0043307 |
1 |
0.046
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.046
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.046
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.046
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.046
|
|
|
|
calcium ion transport into cytosol
|
GO:0060402 |
48 |
0.045
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.045
|
|
|
|
camp metabolic process
|
GO:0046058 |
40 |
0.045
|
|
|
|
activation of phospholipase c activity
|
GO:0007202 |
2 |
0.045
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.044
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.044
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.044
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.044
|
|
|
|
nuclear import
|
GO:0051170 |
95 |
0.044
|
|
|
|
immune response inhibiting cell surface receptor signaling pathway
|
GO:0002767 |
3 |
0.044
|
|
|
|
negative regulation of lymphocyte proliferation
|
GO:0050672 |
45 |
0.043
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.043
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.043
|
|
|
|
positive regulation of alpha beta t cell activation
|
GO:0046635 |
39 |
0.042
|
|
|
|
positive regulation of cyclic nucleotide metabolic process
|
GO:0030801 |
24 |
0.042
|
|
|
|
regulation of granulocyte macrophage colony stimulating factor production
|
GO:0032645 |
3 |
0.042
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.042
|
|
|
|
regulation of monocyte extravasation
|
GO:2000437 |
2 |
0.042
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
114 |
0.042
|
|
|
|
negative regulation of type i hypersensitivity
|
GO:0001811 |
1 |
0.042
|
|
|
|
positive regulation of endocytosis
|
GO:0045807 |
42 |
0.042
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.041
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.041
|
Mouse |
|
|
positive regulation of phagocytosis
|
GO:0050766 |
26 |
0.041
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.041
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.041
|
Mouse |
|
|
tumor necrosis factor production
|
GO:0032640 |
50 |
0.041
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.041
|
|
|
|
actin polymerization or depolymerization
|
GO:0008154 |
54 |
0.041
|
|
|
|
toll like receptor signaling pathway
|
GO:0002224 |
38 |
0.041
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.041
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.040
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.040
|
|
|
|
lysosome localization
|
GO:0032418 |
20 |
0.040
|
|
|
|
positive regulation of angiogenesis
|
GO:0045766 |
46 |
0.040
|
|
|
|
negative regulation of response to wounding
|
GO:1903035 |
77 |
0.040
|
|
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
84 |
0.039
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.039
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.039
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.039
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.039
|
|
|
|
positive regulation of purine nucleotide biosynthetic process
|
GO:1900373 |
26 |
0.039
|
|
|
|
positive regulation of t cell costimulation
|
GO:2000525 |
2 |
0.039
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.039
|
|
|
|
actin filament bundle assembly
|
GO:0051017 |
40 |
0.038
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.038
|
|
|
|
bone remodeling
|
GO:0046849 |
53 |
0.038
|
Mouse |
|
|
regulation of granulocyte chemotaxis
|
GO:0071622 |
17 |
0.038
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.038
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.038
|
|
|
|
negative regulation of secretion by cell
|
GO:1903531 |
54 |
0.037
|
|
|
|
positive regulation of interferon alpha production
|
GO:0032727 |
4 |
0.037
|
|
|
|
cd4 positive alpha beta t cell differentiation involved in immune response
|
GO:0002294 |
28 |
0.037
|
|
|
|
pallium development
|
GO:0021543 |
120 |
0.037
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
53 |
0.037
|
|
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
69 |
0.037
|
|
|
|
eosinophil degranulation
|
GO:0043308 |
1 |
0.037
|
|
|
|
sensitization
|
GO:0046960 |
2 |
0.037
|
|
|
|
cellular response to peptidoglycan
|
GO:0071224 |
4 |
0.036
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.036
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
46 |
0.036
|
Mouse |
|
|
muscle contraction
|
GO:0006936 |
101 |
0.036
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.036
|
|
|
|
neuronal action potential
|
GO:0019228 |
54 |
0.036
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.036
|
|
|
|
keratinocyte migration
|
GO:0051546 |
3 |
0.036
|
|
|
|
tissue migration
|
GO:0090130 |
68 |
0.036
|
|
|
|
telencephalon development
|
GO:0021537 |
186 |
0.036
|
|
|
|
regulation of t cell extravasation
|
GO:2000407 |
3 |
0.036
|
|
|
|
regulation of t cell receptor signaling pathway
|
GO:0050856 |
21 |
0.035
|
|
|
|
response to interferon gamma
|
GO:0034341 |
34 |
0.035
|
|
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.035
|
|
|
|
mesenchyme development
|
GO:0060485 |
152 |
0.035
|
|
|
|
negative regulation of secretion
|
GO:0051048 |
61 |
0.034
|
|
|
|
antimicrobial peptide biosynthetic process
|
GO:0002777 |
2 |
0.034
|
|
|
|
regulation of tumor necrosis factor biosynthetic process
|
GO:0042534 |
10 |
0.034
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.034
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.034
|
|
|
|
macrophage chemotaxis
|
GO:0048246 |
14 |
0.034
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.034
|
|
|
|
b cell differentiation
|
GO:0030183 |
78 |
0.034
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.034
|
|
|
|
ribose phosphate biosynthetic process
|
GO:0046390 |
59 |
0.034
|
|
|
|
complement receptor mediated signaling pathway
|
GO:0002430 |
1 |
0.034
|
|
|
|
regulation of type 2 immune response
|
GO:0002828 |
18 |
0.034
|
|
|
|
positive regulation of lymphocyte differentiation
|
GO:0045621 |
61 |
0.034
|
|
|
|
regulation of protein kinase b signaling
|
GO:0051896 |
56 |
0.034
|
Mouse |
|
|
regulation of cd4 positive alpha beta t cell activation
|
GO:2000514 |
24 |
0.033
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.033
|
|
|
|
leukocyte degranulation
|
GO:0043299 |
27 |
0.033
|
|
|
|
phospholipase c activating g protein coupled receptor signaling pathway
|
GO:0007200 |
26 |
0.033
|
|
|
|
regulation of humoral immune response
|
GO:0002920 |
22 |
0.033
|
|
|
|
eosinophil mediated immunity
|
GO:0002447 |
1 |
0.033
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
45 |
0.033
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.033
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
69 |
0.033
|
|
|
|
gastrin induced gastric acid secretion
|
GO:0001698 |
1 |
0.033
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
127 |
0.033
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.032
|
|
|
|
camp biosynthetic process
|
GO:0006171 |
31 |
0.032
|
|
|
|
b cell proliferation
|
GO:0042100 |
53 |
0.032
|
|
|
|
regulation of cyclic nucleotide biosynthetic process
|
GO:0030802 |
31 |
0.032
|
|
|
|
monocyte extravasation
|
GO:0035696 |
2 |
0.032
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.032
|
|
|
|
negative regulation of vasculature development
|
GO:1901343 |
26 |
0.032
|
|
|
|
inositol lipid mediated signaling
|
GO:0048017 |
41 |
0.032
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
64 |
0.032
|
|
|
|
ribonucleotide biosynthetic process
|
GO:0009260 |
59 |
0.032
|
|
|
|
negative regulation of macrophage apoptotic process
|
GO:2000110 |
3 |
0.032
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
65 |
0.032
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.032
|
|
|
|
microglial cell activation
|
GO:0001774 |
3 |
0.032
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
64 |
0.032
|
|
|
|
positive regulation of fat cell differentiation
|
GO:0045600 |
32 |
0.032
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.031
|
|
