Mus musculus

25 known processes

Kdm4c

lysine (K)-specific demethylase 4C

(Aliases: AA517467,Jmjd2c,Gasc1,2410141F18Rik)

Kdm4c biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
covalent chromatin modification GO:0016569 163 0.122
Human Yeast Fly
negative regulation of neuron death GO:1901215 98 0.062
chromatin organization GO:0006325 206 0.057
Human Yeast Fly
cell type specific apoptotic process GO:0097285 268 0.053
regulation of cellular catabolic process GO:0031329 242 0.052
peptidyl amino acid modification GO:0018193 336 0.050
histone lysine methylation GO:0034968 50 0.050
negative regulation of protein metabolic process GO:0051248 282 0.046
nucleoside phosphate metabolic process GO:0006753 338 0.045
macromolecule catabolic process GO:0009057 281 0.041
regulation of chromatin silencing GO:0031935 2 0.039
transmembrane transport GO:0055085 412 0.039
regulation of cell cycle GO:0051726 281 0.039
cellular amino acid metabolic process GO:0006520 103 0.037
dendrite development GO:0016358 115 0.035
axonogenesis GO:0007409 274 0.035
negative regulation of cellular protein metabolic process GO:0032269 247 0.035
purine ribonucleoside catabolic process GO:0046130 205 0.034
histone modification GO:0016570 159 0.034
Human Yeast Fly
neuron apoptotic process GO:0051402 142 0.034
regulation of cellular ketone metabolic process GO:0010565 66 0.032
protein modification by small protein conjugation GO:0032446 187 0.032
macromolecule methylation GO:0043414 120 0.032
regulation of cellular amino acid metabolic process GO:0006521 5 0.032
purine containing compound metabolic process GO:0072521 311 0.032
purine nucleoside metabolic process GO:0042278 241 0.031
negative regulation of cell proliferation GO:0008285 296 0.030
regulation of proteolysis GO:0030162 164 0.030
nucleotide metabolic process GO:0009117 332 0.030
mitotic cell cycle GO:0000278 195 0.029
ribose phosphate metabolic process GO:0019693 291 0.028
defense response to other organism GO:0098542 197 0.028
nucleoside triphosphate metabolic process GO:0009141 230 0.027
positive regulation of cell development GO:0010720 237 0.027
Rat
positive regulation of dna templated transcription elongation GO:0032786 2 0.027
methylation GO:0032259 134 0.027
negative regulation of intracellular signal transduction GO:1902532 167 0.026
nucleobase containing small molecule metabolic process GO:0055086 352 0.025
immune effector process GO:0002252 321 0.025
regulation of chromosome organization GO:0033044 83 0.025
cellular ketone metabolic process GO:0042180 84 0.025
cellular amine metabolic process GO:0044106 44 0.025
purine nucleoside triphosphate metabolic process GO:0009144 226 0.025
regulation of histone methylation GO:0031060 30 0.025
stem cell differentiation GO:0048863 268 0.024
demethylation GO:0070988 23 0.024
Human Yeast Fly
purine nucleoside catabolic process GO:0006152 205 0.024
cellular homeostasis GO:0019725 240 0.023
chromatin modification GO:0016568 187 0.023
Human Yeast Fly
neural precursor cell proliferation GO:0061351 121 0.023
neuron death GO:0070997 154 0.023
histone lysine demethylation GO:0070076 13 0.022
Human Yeast Fly
chemotaxis GO:0006935 247 0.022
protein catabolic process GO:0030163 221 0.022
nitrogen compound transport GO:0071705 271 0.022
rho protein signal transduction GO:0007266 32 0.022
nucleoside triphosphate catabolic process GO:0009143 205 0.022
muscle cell differentiation GO:0042692 261 0.022
organelle localization GO:0051640 179 0.021
gland development GO:0048732 330 0.021
negative regulation of histone methylation GO:0031061 10 0.021
regulation of engulfment of apoptotic cell GO:1901074 2 0.021
cell substrate adhesion GO:0031589 130 0.021
regulation of neuron death GO:1901214 134 0.021
positive regulation of innate immune response GO:0045089 80 0.020
regulation of chromatin modification GO:1903308 57 0.020
ribonucleoside metabolic process GO:0009119 245 0.020
myeloid cell differentiation GO:0030099 233 0.020
regulation of homeostatic process GO:0032844 182 0.020
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.020
dna repair GO:0006281 107 0.020
sensory organ morphogenesis GO:0090596 242 0.020
positive regulation of cellular amine metabolic process GO:0033240 5 0.020
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.020
histone methylation GO:0016571 71 0.020
negative regulation of molecular function GO:0044092 258 0.020
forebrain development GO:0030900 302 0.020
leukocyte differentiation GO:0002521 342 0.019
regulation of hydrolase activity GO:0051336 246 0.019
organic cyclic compound catabolic process GO:1901361 295 0.019
positive regulation of nervous system development GO:0051962 221 0.019
Rat
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.019
protein modification by small protein conjugation or removal GO:0070647 207 0.019
ribonucleoside triphosphate metabolic process GO:0009199 220 0.019
microtubule based process GO:0007017 236 0.019
response to organonitrogen compound GO:0010243 246 0.019
glycosyl compound metabolic process GO:1901657 246 0.018
cation transport GO:0006812 399 0.018
ribonucleoside monophosphate metabolic process GO:0009161 80 0.018
regulation of protein catabolic process GO:0042176 108 0.018
response to growth factor GO:0070848 198 0.018
regulation of cellular amine metabolic process GO:0033238 20 0.018
purine ribonucleotide metabolic process GO:0009150 290 0.018
purine nucleoside monophosphate metabolic process GO:0009126 81 0.018
homeostasis of number of cells GO:0048872 210 0.018
ribonucleotide catabolic process GO:0009261 208 0.018
protein maturation GO:0051604 176 0.017
positive regulation of cellular catabolic process GO:0031331 148 0.017
histone demethylation GO:0016577 13 0.017
Human Yeast Fly
cellular response to lipid GO:0071396 145 0.017
purine ribonucleoside metabolic process GO:0046128 241 0.017
regulation of secretion GO:0051046 274 0.016
regulation of hormone levels GO:0010817 211 0.016
protein processing GO:0016485 163 0.016
ion transmembrane transport GO:0034220 361 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.016
regionalization GO:0003002 337 0.016
cellular response to hormone stimulus GO:0032870 150 0.016
negative regulation of neuron apoptotic process GO:0043524 92 0.016
cytokine production GO:0001816 319 0.016
endomembrane system organization GO:0010256 147 0.016
positive regulation of protein modification process GO:0031401 299 0.016
protein ubiquitination GO:0016567 171 0.016
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.016
nucleoside catabolic process GO:0009164 206 0.016
purine nucleoside triphosphate catabolic process GO:0009146 203 0.015
positive regulation of apoptotic process GO:0043065 217 0.015
glucose homeostasis GO:0042593 128 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.015
maintenance of location GO:0051235 89 0.015
ribonucleotide metabolic process GO:0009259 291 0.015
hematopoietic progenitor cell differentiation GO:0002244 143 0.015
ribonucleoside catabolic process GO:0042454 206 0.015
regulation of chromatin organization GO:1902275 57 0.015
synaptic transmission GO:0007268 329 0.015
establishment of protein localization to vacuole GO:0072666 4 0.015
protein methylation GO:0006479 81 0.015
organic hydroxy compound metabolic process GO:1901615 203 0.015
carbohydrate derivative catabolic process GO:1901136 231 0.015
nucleoside metabolic process GO:0009116 246 0.014
ras protein signal transduction GO:0007265 77 0.014
stem cell development GO:0048864 219 0.014
regulation of rho gtpase activity GO:0032319 58 0.014
regulation of organelle organization GO:0033043 289 0.014
stem cell proliferation GO:0072089 117 0.014
regulation of cytokine production GO:0001817 266 0.014
positive regulation of proteolysis GO:0045862 85 0.014
carbohydrate derivative biosynthetic process GO:1901137 183 0.014
dephosphorylation GO:0016311 129 0.014
cellular carbohydrate metabolic process GO:0044262 119 0.014
positive regulation of programmed cell death GO:0043068 218 0.014
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.014
protein alkylation GO:0008213 81 0.013
metal ion homeostasis GO:0055065 189 0.013
protein targeting to vacuole GO:0006623 3 0.013
regulation of cellular response to stress GO:0080135 159 0.013
histone h3 k9 methylation GO:0051567 17 0.013
placenta development GO:0001890 140 0.013
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.013
protein targeting GO:0006605 143 0.013
posttranscriptional regulation of gene expression GO:0010608 155 0.013
protein localization to organelle GO:0033365 185 0.013
aromatic compound catabolic process GO:0019439 286 0.013
regulation of nucleoside metabolic process GO:0009118 130 0.013
nucleoside monophosphate metabolic process GO:0009123 85 0.013
apoptotic signaling pathway GO:0097190 306 0.013
negative regulation of phosphorus metabolic process GO:0010563 184 0.013
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 3 0.013
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.013
carbohydrate metabolic process GO:0005975 230 0.013
cellular response to growth factor stimulus GO:0071363 197 0.013
negative regulation of cell cycle GO:0045786 123 0.013
cellular response to cytokine stimulus GO:0071345 189 0.013
heterocycle catabolic process GO:0046700 280 0.013
organophosphate catabolic process GO:0046434 232 0.013
regulation of ion transport GO:0043269 215 0.013
protein localization to nucleus GO:0034504 121 0.013
positive regulation of engulfment of apoptotic cell GO:1901076 1 0.013
pharynx development GO:0060465 1 0.012
regulation of vesicle mediated transport GO:0060627 139 0.012
mapk cascade GO:0000165 281 0.012
dna metabolic process GO:0006259 303 0.012
protein dealkylation GO:0008214 13 0.012
Human Yeast Fly
anatomical structure homeostasis GO:0060249 145 0.012
muscle cell development GO:0055001 133 0.012
glycoprotein metabolic process GO:0009100 116 0.012
modification dependent protein catabolic process GO:0019941 133 0.012
purine nucleotide metabolic process GO:0006163 302 0.012
regulation of neuron projection development GO:0010975 169 0.012
regulation of histone modification GO:0031056 56 0.012
cellular chemical homeostasis GO:0055082 215 0.012
negative regulation of androgen receptor signaling pathway GO:0060766 3 0.012
regulation of protein maturation GO:1903317 96 0.012
regulation of secretion by cell GO:1903530 249 0.012
cellularization GO:0007349 1 0.012
compound eye development GO:0048749 1 0.012
skeletal muscle organ development GO:0060538 163 0.012
carbohydrate homeostasis GO:0033500 128 0.012
regulation of mitotic cell cycle GO:0007346 126 0.012
dendritic spine development GO:0060996 30 0.012
defense response to bacterium GO:0042742 119 0.012
response to nutrient levels GO:0031667 109 0.012
Yeast
g protein coupled receptor signaling pathway GO:0007186 243 0.012
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.011
cellular ion homeostasis GO:0006873 165 0.011
lymphocyte differentiation GO:0030098 242 0.011
negative regulation of chromatin silencing GO:0031936 1 0.011
regulation of protein processing GO:0070613 96 0.011
cellular response to fibroblast growth factor stimulus GO:0044344 47 0.011
proteasomal protein catabolic process GO:0010498 98 0.011
negative regulation of cellular component organization GO:0051129 194 0.011
amine metabolic process GO:0009308 45 0.011
developmental maturation GO:0021700 193 0.011
defecation GO:0030421 1 0.011
positive regulation of cell death GO:0010942 224 0.011
response to extracellular stimulus GO:0009991 127 0.011
Yeast
response to inorganic substance GO:0010035 96 0.011
cation transmembrane transport GO:0098655 266 0.011
telencephalon development GO:0021537 186 0.011
regulation of purine nucleotide metabolic process GO:1900542 169 0.011
regulation of cell projection organization GO:0031344 206 0.011
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.011
cation homeostasis GO:0055080 212 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.011
phospholipid metabolic process GO:0006644 87 0.011
Yeast
cellular protein catabolic process GO:0044257 155 0.011
glycerolipid metabolic process GO:0046486 122 0.011
mitotic cell cycle process GO:1903047 159 0.011
inorganic ion transmembrane transport GO:0098660 234 0.011
membrane organization GO:0061024 245 0.011
sensory perception GO:0007600 245 0.011
regulation of histone h3 k9 methylation GO:0051570 8 0.011
actin cytoskeleton organization GO:0030036 220 0.011
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.011
positive regulation of chromosome organization GO:2001252 33 0.010
regulation of mapk cascade GO:0043408 248 0.010
engulfment of apoptotic cell GO:0043652 3 0.010
cytoplasmic transport GO:0016482 234 0.010
negative regulation of phosphate metabolic process GO:0045936 184 0.010
maintenance of protein location in nucleus GO:0051457 2 0.010
dendritic spine organization GO:0097061 26 0.010
t cell differentiation GO:0030217 174 0.010
regulation of cell cycle process GO:0010564 160 0.010
negative regulation of cellular amine metabolic process GO:0033239 1 0.010
activation of immune response GO:0002253 138 0.010
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.010
regulation of protein sumoylation GO:0033233 4 0.010
organophosphate biosynthetic process GO:0090407 122 0.010
Yeast
positive regulation of hydrolase activity GO:0051345 148 0.010
early endosome to late endosome transport GO:0045022 2 0.010
regulation of establishment of protein localization GO:0070201 181 0.010
cellular response to organonitrogen compound GO:0071417 145 0.010
regulation of neuron apoptotic process GO:0043523 122 0.010
regulation of stem cell proliferation GO:0072091 78 0.010
digestive system development GO:0055123 200 0.010

Kdm4c disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.032
disease of anatomical entity DOID:7 0 0.032
eye and adnexa disease DOID:1492 0 0.021
retinal disease DOID:5679 0 0.021
sensory system disease DOID:0050155 0 0.021
eye disease DOID:5614 0 0.021
organ system cancer DOID:0050686 0 0.018
disease of cellular proliferation DOID:14566 0 0.018
cancer DOID:162 0 0.018
neurodegenerative disease DOID:1289 0 0.013
central nervous system disease DOID:331 0 0.013