Mus musculus

44 known processes

Khk

ketohexokinase

Khk biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oxidation reduction process GO:0055114 342 0.311
transmembrane transport GO:0055085 412 0.114
small molecule biosynthetic process GO:0044283 132 0.111
fat soluble vitamin biosynthetic process GO:0042362 4 0.109
amine metabolic process GO:0009308 45 0.104
hexose metabolic process GO:0019318 98 0.098
cofactor metabolic process GO:0051186 80 0.091
cellular amino acid metabolic process GO:0006520 103 0.083
alcohol metabolic process GO:0006066 116 0.082
nitrogen compound transport GO:0071705 271 0.080
coenzyme metabolic process GO:0006732 52 0.079
alpha amino acid metabolic process GO:1901605 59 0.078
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.073
glucose metabolic process GO:0006006 92 0.072
response to organonitrogen compound GO:0010243 246 0.068
Rat
sulfur compound metabolic process GO:0006790 100 0.068
steroid metabolic process GO:0008202 119 0.067
fat cell differentiation GO:0045444 160 0.059
reactive oxygen species metabolic process GO:0072593 84 0.055
regulation of cellular ketone metabolic process GO:0010565 66 0.054
positive regulation of dopamine secretion GO:0033603 2 0.054
nitrobenzene metabolic process GO:0018916 1 0.052
monosaccharide metabolic process GO:0005996 106 0.047
regulation of cellular amine metabolic process GO:0033238 20 0.047
fatty acid metabolic process GO:0006631 121 0.044
response to organic cyclic compound GO:0014070 198 0.044
cellular lipid metabolic process GO:0044255 323 0.042
ammonia assimilation cycle GO:0019676 2 0.042
response to acid chemical GO:0001101 111 0.040
purine containing compound metabolic process GO:0072521 311 0.040
steroid biosynthetic process GO:0006694 47 0.040
nucleobase containing small molecule metabolic process GO:0055086 352 0.039
organic hydroxy compound metabolic process GO:1901615 203 0.039
regulation of cellular amino acid metabolic process GO:0006521 5 0.038
cellular amine metabolic process GO:0044106 44 0.038
carbohydrate biosynthetic process GO:0016051 74 0.037
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.037
carbohydrate metabolic process GO:0005975 230 0.037
organonitrogen compound biosynthetic process GO:1901566 192 0.037
regulation of glucose metabolic process GO:0010906 60 0.036
cation transport GO:0006812 399 0.034
regulation of reactive oxygen species metabolic process GO:2000377 40 0.033
cellular response to lipid GO:0071396 145 0.033
cation transmembrane transport GO:0098655 266 0.032
response to peptide hormone GO:0043434 127 0.032
Rat
glutathione metabolic process GO:0006749 16 0.032
regulation of hormone levels GO:0010817 211 0.032
calcitriol biosynthetic process from calciol GO:0036378 3 0.031
glycosyl compound metabolic process GO:1901657 246 0.031
cellular response to dna damage stimulus GO:0006974 207 0.031
vitamin metabolic process GO:0006766 23 0.030
positive regulation of programmed cell death GO:0043068 218 0.030
dna metabolic process GO:0006259 303 0.030
ion transmembrane transport GO:0034220 361 0.030
cellular modified amino acid metabolic process GO:0006575 63 0.030
regulation of nitrogen cycle metabolic process GO:1903314 1 0.029
anion transport GO:0006820 177 0.029
lipid biosynthetic process GO:0008610 179 0.029
heterocycle catabolic process GO:0046700 280 0.029
organic acid biosynthetic process GO:0016053 86 0.029
purine nucleoside metabolic process GO:0042278 241 0.028
cellular homeostasis GO:0019725 240 0.028
organic cyclic compound catabolic process GO:1901361 295 0.028
blood circulation GO:0008015 195 0.028
cellular alcohol metabolic process GO:0044107 3 0.027
response to oxygen levels GO:0070482 62 0.027
cellular amide metabolic process GO:0043603 58 0.027
hormone metabolic process GO:0042445 86 0.027
nucleoside phosphate metabolic process GO:0006753 338 0.027
cellular alcohol biosynthetic process GO:0044108 3 0.026
cofactor transport GO:0051181 4 0.026
protein catabolic process GO:0030163 221 0.026
sperm motility GO:0030317 47 0.026
one carbon metabolic process GO:0006730 1 0.026
neurotransmitter transport GO:0006836 76 0.025
purine ribonucleoside metabolic process GO:0046128 241 0.025
response to insulin GO:0032868 100 0.025
Rat
lactation GO:0007595 25 0.025
vitamin d biosynthetic process GO:0042368 3 0.025
positive regulation of apoptotic process GO:0043065 217 0.025
multi multicellular organism process GO:0044706 109 0.024
cellular ketone metabolic process GO:0042180 84 0.024
macromolecule catabolic process GO:0009057 281 0.024
circulatory system process GO:0003013 197 0.024
t cell activation GO:0042110 289 0.024
maintenance of location GO:0051235 89 0.023
xenobiotic catabolic process GO:0042178 1 0.023
response to inorganic substance GO:0010035 96 0.023
Rat
inorganic cation transmembrane transport GO:0098662 207 0.023
regulation of secretion GO:0051046 274 0.023
cellular amino acid biosynthetic process GO:0008652 22 0.023
organic hydroxy compound biosynthetic process GO:1901617 77 0.022
organic hydroxy compound transport GO:0015850 93 0.022
purine ribonucleotide metabolic process GO:0009150 290 0.022
reactive nitrogen species metabolic process GO:2001057 0 0.021
apoptotic signaling pathway GO:0097190 306 0.021
ovarian follicle development GO:0001541 40 0.021
camera type eye development GO:0043010 266 0.021
negative regulation of molecular function GO:0044092 258 0.021
positive regulation of cell death GO:0010942 224 0.021
cell killing GO:0001906 67 0.021
cellular response to organonitrogen compound GO:0071417 145 0.021
response to extracellular stimulus GO:0009991 127 0.020
nucleotide metabolic process GO:0009117 332 0.020
regulation of secretion by cell GO:1903530 249 0.020
purine nucleotide metabolic process GO:0006163 302 0.020
response to bile acid GO:1903412 1 0.020
cellular nitrogen compound catabolic process GO:0044270 280 0.020
negative regulation of cellular protein metabolic process GO:0032269 247 0.020
gonad development GO:0008406 141 0.020
positive regulation of catecholamine secretion GO:0033605 2 0.020
protein maturation GO:0051604 176 0.020
response to peptide GO:1901652 136 0.020
Rat
negative regulation of cell proliferation GO:0008285 296 0.020
nucleoside metabolic process GO:0009116 246 0.020
response to decreased oxygen levels GO:0036293 59 0.019
skeletal muscle organ development GO:0060538 163 0.019
regulation of apoptotic signaling pathway GO:2001233 197 0.019
fat soluble vitamin metabolic process GO:0006775 11 0.019
regulation of carbohydrate metabolic process GO:0006109 75 0.019
cellular response to acid chemical GO:0071229 68 0.019
dna catabolic process endonucleolytic GO:0000737 15 0.019
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.018
cellular response to external stimulus GO:0071496 88 0.018
multicellular organismal homeostasis GO:0048871 164 0.018
cellular carbohydrate metabolic process GO:0044262 119 0.018
immune effector process GO:0002252 321 0.018
rhythmic process GO:0048511 174 0.018
response to nutrient levels GO:0031667 109 0.018
response to drug GO:0042493 75 0.018
regulation of feeding behavior GO:0060259 3 0.018
interleukin 8 production GO:0032637 4 0.018
regulation of organelle organization GO:0033043 289 0.017
regulation of neuron death GO:1901214 134 0.017
monocarboxylic acid metabolic process GO:0032787 191 0.017
alcohol biosynthetic process GO:0046165 43 0.017
cellular response to hormone stimulus GO:0032870 150 0.017
positive regulation of fatty acid oxidation GO:0046321 4 0.017
urogenital system development GO:0001655 261 0.017
regulation of ammonia assimilation cycle GO:2001248 1 0.017
cellular response to cadmium ion GO:0071276 3 0.017
ribonucleotide metabolic process GO:0009259 291 0.017
regulation of interleukin 8 production GO:0032677 3 0.017
response to nitrosative stress GO:0051409 1 0.017
regulation of vitamin metabolic process GO:0030656 3 0.016
myeloid cell differentiation GO:0030099 233 0.016
organonitrogen compound catabolic process GO:1901565 264 0.016
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.016
negative regulation of protein metabolic process GO:0051248 282 0.016
positive regulation of mammary gland involution GO:1903521 4 0.016
cell growth GO:0016049 130 0.016
response to oxidative stress GO:0006979 123 0.016
amide transport GO:0042886 138 0.016
spermatogenesis GO:0007283 284 0.016
generation of precursor metabolites and energy GO:0006091 103 0.016
ribonucleoside metabolic process GO:0009119 245 0.016
response to hypoxia GO:0001666 58 0.015
organic anion transport GO:0015711 137 0.015
cytokine production GO:0001816 319 0.015
potassium ion transmembrane transport GO:0071805 43 0.015
ear development GO:0043583 200 0.015
reactive oxygen species biosynthetic process GO:1903409 8 0.015
peptide transport GO:0015833 133 0.015
regulation of hormone secretion GO:0046883 88 0.015
regulation of glutamine family amino acid metabolic process GO:0000820 1 0.015
dicarboxylic acid metabolic process GO:0043648 18 0.015
secondary alcohol metabolic process GO:1902652 3 0.015
respiratory system development GO:0060541 190 0.015
neuron death GO:0070997 154 0.015
response to radiation GO:0009314 165 0.015
aromatic compound catabolic process GO:0019439 286 0.015
retinoid metabolic process GO:0001523 24 0.015
membrane organization GO:0061024 245 0.015
dephosphorylation GO:0016311 129 0.015
cellular macromolecule catabolic process GO:0044265 206 0.015
gland development GO:0048732 330 0.015
cofactor biosynthetic process GO:0051188 41 0.015
defense response to other organism GO:0098542 197 0.015
sterol metabolic process GO:0016125 58 0.015
cellular response to extracellular stimulus GO:0031668 81 0.015
cell type specific apoptotic process GO:0097285 268 0.015
connective tissue development GO:0061448 179 0.014
carboxylic acid biosynthetic process GO:0046394 86 0.014
regulation of glutamate metabolic process GO:2000211 1 0.014
positive regulation of cellular amine metabolic process GO:0033240 5 0.014
development of primary female sexual characteristics GO:0046545 73 0.014
stem cell differentiation GO:0048863 268 0.014
meiotic nuclear division GO:0007126 115 0.014
short chain fatty acid catabolic process GO:0019626 2 0.014
acyl coa metabolic process GO:0006637 19 0.014
monosaccharide biosynthetic process GO:0046364 44 0.014
sulfur compound biosynthetic process GO:0044272 37 0.014
retina development in camera type eye GO:0060041 119 0.014
small molecule catabolic process GO:0044282 71 0.014
multicellular organism growth GO:0035264 161 0.014
vitamin d3 metabolic process GO:0070640 3 0.014
hexose biosynthetic process GO:0019319 39 0.014
nucleoside monophosphate metabolic process GO:0009123 85 0.014
carboxylic acid catabolic process GO:0046395 51 0.014
midgut development GO:0007494 4 0.013
regulation of homeostatic process GO:0032844 182 0.013
gluconeogenesis GO:0006094 39 0.013
muscle tissue development GO:0060537 308 0.013
lipoprotein metabolic process GO:0042157 43 0.013
organelle fission GO:0048285 170 0.013
positive regulation of secretion GO:0051047 130 0.013
positive regulation of secretion by cell GO:1903532 114 0.013
striated muscle tissue development GO:0014706 293 0.013
regulation of cell activation GO:0050865 289 0.013
cellular response to insulin stimulus GO:0032869 78 0.013
carbohydrate derivative biosynthetic process GO:1901137 183 0.013
regulation of vitamin d biosynthetic process GO:0060556 1 0.013
cd4 positive alpha beta t cell activation GO:0035710 45 0.013
oocyte construction GO:0007308 2 0.013
regulation of urea metabolic process GO:0034255 1 0.013
glycoprotein metabolic process GO:0009100 116 0.013
germ cell development GO:0007281 185 0.013
regulation of response to wounding GO:1903034 189 0.013
carbohydrate homeostasis GO:0033500 128 0.013
cellular chemical homeostasis GO:0055082 215 0.013
regulation of neurotransmitter levels GO:0001505 87 0.013
hexose catabolic process GO:0019320 3 0.013
dna repair GO:0006281 107 0.013
leukocyte differentiation GO:0002521 342 0.013
body fluid secretion GO:0007589 53 0.013
ribonucleoside monophosphate metabolic process GO:0009161 80 0.013
peptide hormone secretion GO:0030072 109 0.012
methylation GO:0032259 134 0.012
neuron apoptotic process GO:0051402 142 0.012
peptide metabolic process GO:0006518 46 0.012
purine ribonucleoside catabolic process GO:0046130 205 0.012
insulin secretion GO:0030073 89 0.012
response to molecule of bacterial origin GO:0002237 143 0.012
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.012
divalent metal ion transport GO:0070838 172 0.012
regulation of protein processing GO:0070613 96 0.012
glutamate metabolic process GO:0006536 9 0.012
acetylcholine transport GO:0015870 2 0.012
directional locomotion GO:0033058 3 0.012
actin cytoskeleton organization GO:0030036 220 0.012
response to uv GO:0009411 44 0.012
amino acid transmembrane transport GO:0003333 37 0.012
regulation of multi organism process GO:0043900 111 0.012
locomotory behavior GO:0007626 195 0.012
negative regulation of neuron death GO:1901215 98 0.012
nuclear transport GO:0051169 139 0.012
t cell differentiation GO:0030217 174 0.012
amino acid transport GO:0006865 61 0.012
developmental growth involved in morphogenesis GO:0060560 138 0.012
positive regulation of lymphocyte activation GO:0051251 140 0.012
lytic vacuole organization GO:0080171 21 0.012
folic acid containing compound metabolic process GO:0006760 3 0.012
meiotic cell cycle GO:0051321 122 0.012
posttranscriptional regulation of gene expression GO:0010608 155 0.012
catecholamine uptake GO:0090493 4 0.012
polyol metabolic process GO:0019751 26 0.012
regulation of body fluid levels GO:0050878 162 0.012
mapk cascade GO:0000165 281 0.012
coenzyme biosynthetic process GO:0009108 23 0.012
response to retinoic acid GO:0032526 56 0.012
positive regulation of apoptotic process involved in morphogenesis GO:1902339 4 0.012
organ regeneration GO:0031100 2 0.012
lipid localization GO:0010876 126 0.012
cellular response to organic cyclic compound GO:0071407 87 0.012
regulation of lymphocyte activation GO:0051249 240 0.012
regulation of blood pressure GO:0008217 93 0.012
development of primary sexual characteristics GO:0045137 143 0.011
cellular response to peptide hormone stimulus GO:0071375 92 0.011
monoamine transport GO:0015844 33 0.011
regulation of kinase activity GO:0043549 249 0.011
regulation of cell cycle GO:0051726 281 0.011
rhombomere formation GO:0021594 1 0.011
aspartate family amino acid metabolic process GO:0009066 10 0.011
ribonucleoside catabolic process GO:0042454 206 0.011
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.011
positive regulation of camp mediated signaling GO:0043950 3 0.011
endocrine system development GO:0035270 98 0.011
ovulation cycle GO:0042698 59 0.011
regulation of cellular component biogenesis GO:0044087 181 0.011
response to light stimulus GO:0009416 135 0.011
divalent inorganic cation homeostasis GO:0072507 138 0.011
sialylation GO:0097503 14 0.011
regulation of membrane potential GO:0042391 192 0.011
positive regulation of growth GO:0045927 104 0.011
phospholipid transfer to membrane GO:0006649 2 0.011
monocarboxylic acid biosynthetic process GO:0072330 61 0.011
negative regulation of cellular component organization GO:0051129 194 0.011
regulation of cytokine production GO:0001817 266 0.011
positive regulation of protein modification process GO:0031401 299 0.011
negative regulation of intracellular signal transduction GO:1902532 167 0.011
interleukin 8 secretion GO:0072606 3 0.011
anion transmembrane transport GO:0098656 71 0.011
protein processing GO:0016485 163 0.011
glutamine family amino acid metabolic process GO:0009064 15 0.011
regulation of cellular ketone metabolic process by regulation of transcription from rna polymerase ii promoter GO:0072364 7 0.011
regulation of neuron apoptotic process GO:0043523 122 0.011
leukocyte mediated cytotoxicity GO:0001909 62 0.011
multicellular organismal signaling GO:0035637 91 0.011
neurotransmitter secretion GO:0007269 62 0.011
carbohydrate catabolic process GO:0016052 32 0.011
regulation of ion transport GO:0043269 215 0.011
innate immune response GO:0045087 157 0.011
purine containing compound biosynthetic process GO:0072522 70 0.011
regulation of systemic arterial blood pressure GO:0003073 61 0.011
regulation of neuron differentiation GO:0045664 281 0.011
adult behavior GO:0030534 135 0.011
female sex differentiation GO:0046660 84 0.011
ribose phosphate metabolic process GO:0019693 291 0.011
cholesterol storage GO:0010878 4 0.011
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.011
benzene containing compound metabolic process GO:0042537 5 0.011
divalent inorganic cation transport GO:0072511 178 0.010
calcium ion homeostasis GO:0055074 127 0.010
intestinal absorption GO:0050892 13 0.010
regulation of peptide secretion GO:0002791 77 0.010
cellular response to bile acid GO:1903413 1 0.010
metal ion homeostasis GO:0055065 189 0.010
atp metabolic process GO:0046034 75 0.010
inorganic ion transmembrane transport GO:0098660 234 0.010
regulation of ion transmembrane transport GO:0034765 119 0.010
regulation of cell killing GO:0031341 40 0.010
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.010
regulation of fat cell differentiation GO:0045598 81 0.010
compound eye development GO:0048749 1 0.010
protein oligomerization GO:0051259 67 0.010
endomembrane system organization GO:0010256 147 0.010
peptidyl amino acid modification GO:0018193 336 0.010
apoptotic process involved in mammary gland involution GO:0060057 4 0.010
nitrogen cycle metabolic process GO:0071941 3 0.010
negative regulation of apoptotic signaling pathway GO:2001234 104 0.010
circadian regulation of gene expression GO:0032922 48 0.010
regulation of cellular catabolic process GO:0031329 242 0.010

Khk disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.043
inherited metabolic disorder DOID:655 0 0.029
disease of anatomical entity DOID:7 0 0.022
nervous system disease DOID:863 0 0.022
sensory system disease DOID:0050155 0 0.019
immune system disease DOID:2914 0 0.018
organ system cancer DOID:0050686 0 0.016
disease of cellular proliferation DOID:14566 0 0.016
cancer DOID:162 0 0.016
eye and adnexa disease DOID:1492 0 0.012
eye disease DOID:5614 0 0.012
carbohydrate metabolic disorder DOID:2978 0 0.012
central nervous system disease DOID:331 0 0.011