Mus musculus

281 known processes

Prdx2

peroxiredoxin 2

(Aliases: TPx,Tdpx1,TDX1,Band-8,TR,AL022839,TPx-B,TSA,Torin,PrxII,NkefB,PRP)

Prdx2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organonitrogen compound biosynthetic process GO:1901566 192 0.135
oxidation reduction process GO:0055114 342 0.114
Human Yeast Mouse Worm
ribose phosphate metabolic process GO:0019693 291 0.113
purine ribonucleoside metabolic process GO:0046128 241 0.110
purine containing compound metabolic process GO:0072521 311 0.107
purine nucleotide metabolic process GO:0006163 302 0.106
ribonucleotide metabolic process GO:0009259 291 0.097
ribonucleoside triphosphate metabolic process GO:0009199 220 0.095
nucleotide metabolic process GO:0009117 332 0.092
cellular amino acid metabolic process GO:0006520 103 0.091
Mouse
response to oxidative stress GO:0006979 123 0.087
nucleoside phosphate metabolic process GO:0006753 338 0.079
purine nucleoside metabolic process GO:0042278 241 0.078
cation transport GO:0006812 399 0.074
glutathione metabolic process GO:0006749 16 0.071
purine nucleoside triphosphate metabolic process GO:0009144 226 0.070
purine ribonucleotide metabolic process GO:0009150 290 0.066
nucleoside monophosphate metabolic process GO:0009123 85 0.064
cellular homeostasis GO:0019725 240 0.064
Yeast Mouse
mitochondrion organization GO:0007005 134 0.063
glycosyl compound metabolic process GO:1901657 246 0.062
nucleobase containing small molecule metabolic process GO:0055086 352 0.062
organic cyclic compound catabolic process GO:1901361 295 0.059
ion transmembrane transport GO:0034220 361 0.057
nucleoside phosphate catabolic process GO:1901292 222 0.057
nucleoside metabolic process GO:0009116 246 0.056
protein catabolic process GO:0030163 221 0.054
nucleoside triphosphate metabolic process GO:0009141 230 0.051
ribonucleoside metabolic process GO:0009119 245 0.051
regulation of transferase activity GO:0051338 263 0.050
nucleoside catabolic process GO:0009164 206 0.050
regulation of cellular ketone metabolic process GO:0010565 66 0.049
ribonucleoside triphosphate catabolic process GO:0009203 199 0.048
cellular response to dna damage stimulus GO:0006974 207 0.048
response to organic cyclic compound GO:0014070 198 0.048
aromatic compound catabolic process GO:0019439 286 0.047
heterocycle catabolic process GO:0046700 280 0.043
nucleotide catabolic process GO:0009166 217 0.043
myeloid cell differentiation GO:0030099 233 0.043
Mouse
atp metabolic process GO:0046034 75 0.042
carbohydrate derivative catabolic process GO:1901136 231 0.041
purine nucleoside monophosphate metabolic process GO:0009126 81 0.040
transmembrane transport GO:0055085 412 0.039
nucleoside triphosphate catabolic process GO:0009143 205 0.039
macromolecule catabolic process GO:0009057 281 0.039
organonitrogen compound catabolic process GO:1901565 264 0.039
ribonucleoside catabolic process GO:0042454 206 0.038
positive regulation of protein modification process GO:0031401 299 0.037
purine ribonucleoside catabolic process GO:0046130 205 0.037
inorganic ion transmembrane transport GO:0098660 234 0.037
sulfur compound metabolic process GO:0006790 100 0.036
cellular ion homeostasis GO:0006873 165 0.035
ribonucleotide catabolic process GO:0009261 208 0.035
cellular response to oxidative stress GO:0034599 76 0.035
positive regulation of cell death GO:0010942 224 0.035
cellular nitrogen compound catabolic process GO:0044270 280 0.035
cation homeostasis GO:0055080 212 0.034
regulation of protein kinase activity GO:0045859 232 0.034
purine containing compound catabolic process GO:0072523 213 0.034
carbohydrate derivative biosynthetic process GO:1901137 183 0.033
purine nucleoside catabolic process GO:0006152 205 0.033
cellular ketone metabolic process GO:0042180 84 0.033
regulation of cellular response to stress GO:0080135 159 0.033
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.033
glycosyl compound catabolic process GO:1901658 206 0.033
sensory perception GO:0007600 245 0.033
organophosphate catabolic process GO:0046434 232 0.033
monocarboxylic acid metabolic process GO:0032787 191 0.032
Mouse
spermatogenesis GO:0007283 284 0.032
Mouse
purine nucleotide catabolic process GO:0006195 211 0.032
amine metabolic process GO:0009308 45 0.031
regulation of cellular amine metabolic process GO:0033238 20 0.031
reactive oxygen species metabolic process GO:0072593 84 0.031
cellular modified amino acid metabolic process GO:0006575 63 0.031
Mouse
response to inorganic substance GO:0010035 96 0.030
negative regulation of molecular function GO:0044092 258 0.030
locomotory behavior GO:0007626 195 0.030
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.030
carbohydrate metabolic process GO:0005975 230 0.030
male gamete generation GO:0048232 285 0.028
Mouse
metal ion homeostasis GO:0055065 189 0.028
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.028
regulation of ion transport GO:0043269 215 0.027
regulation of transmembrane transport GO:0034762 128 0.026
cation transmembrane transport GO:0098655 266 0.026
inflammatory response GO:0006954 244 0.026
homeostasis of number of cells GO:0048872 210 0.026
posttranscriptional regulation of gene expression GO:0010608 155 0.025
purine nucleoside triphosphate catabolic process GO:0009146 203 0.025
organic acid biosynthetic process GO:0016053 86 0.025
negative regulation of cellular protein metabolic process GO:0032269 247 0.025
response to reactive oxygen species GO:0000302 56 0.025
intracellular protein transport GO:0006886 204 0.024
Mouse
apoptotic signaling pathway GO:0097190 306 0.024
protein maturation GO:0051604 176 0.024
Mouse
regulation of hydrolase activity GO:0051336 246 0.024
nucleoside monophosphate catabolic process GO:0009125 59 0.023
proton transport GO:0015992 35 0.023
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.023
nucleoside phosphate biosynthetic process GO:1901293 79 0.023
response to iron ion GO:0010039 4 0.023
nucleotide biosynthetic process GO:0009165 78 0.023
organophosphate biosynthetic process GO:0090407 122 0.023
regulation of kinase activity GO:0043549 249 0.022
cofactor biosynthetic process GO:0051188 41 0.022
regulation of organelle organization GO:0033043 289 0.022
cellular macromolecule catabolic process GO:0044265 206 0.022
cellular amine metabolic process GO:0044106 44 0.021
protein processing GO:0016485 163 0.021
response to organonitrogen compound GO:0010243 246 0.021
inorganic cation transmembrane transport GO:0098662 207 0.021
regulation of cellular amino acid metabolic process GO:0006521 5 0.021
carboxylic acid biosynthetic process GO:0046394 86 0.021
purine ribonucleotide catabolic process GO:0009154 208 0.020
regulation of intracellular transport GO:0032386 159 0.020
Mouse
adult locomotory behavior GO:0008344 91 0.020
synaptic transmission GO:0007268 329 0.020
positive regulation of cellular amine metabolic process GO:0033240 5 0.020
energy derivation by oxidation of organic compounds GO:0015980 77 0.020
myeloid cell homeostasis GO:0002262 114 0.020
Mouse
circulatory system process GO:0003013 197 0.019
adult behavior GO:0030534 135 0.019
leukocyte differentiation GO:0002521 342 0.019
cellular amino acid biosynthetic process GO:0008652 22 0.019
regulation of secretion GO:0051046 274 0.019
cellular response to lipid GO:0071396 145 0.019
cellular chemical homeostasis GO:0055082 215 0.019
purine containing compound biosynthetic process GO:0072522 70 0.019
protein modification by small protein conjugation or removal GO:0070647 207 0.019
ribonucleoside monophosphate metabolic process GO:0009161 80 0.018
regulation of anatomical structure size GO:0090066 178 0.018
endocytosis GO:0006897 168 0.018
cytokine production GO:0001816 319 0.018
muscle tissue development GO:0060537 308 0.018
cellular metal ion homeostasis GO:0006875 151 0.018
regulation of cellular catabolic process GO:0031329 242 0.018
atp catabolic process GO:0006200 55 0.018
regulation of purine nucleotide metabolic process GO:1900542 169 0.018
regulation of apoptotic signaling pathway GO:2001233 197 0.018
cellular component assembly involved in morphogenesis GO:0010927 139 0.017
purine nucleoside biosynthetic process GO:0042451 19 0.017
myosin filament organization GO:0031033 3 0.017
generation of precursor metabolites and energy GO:0006091 103 0.017
peptide metabolic process GO:0006518 46 0.017
organelle assembly GO:0070925 177 0.017
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.017
peptidyl amino acid modification GO:0018193 336 0.017
cytoplasmic transport GO:0016482 234 0.016
Mouse
positive regulation of programmed cell death GO:0043068 218 0.016
hydrogen transport GO:0006818 35 0.016
regulation of cell cycle GO:0051726 281 0.016
nitrogen compound transport GO:0071705 271 0.016
Mouse
membrane organization GO:0061024 245 0.016
carbohydrate catabolic process GO:0016052 32 0.016
protein modification by small protein conjugation GO:0032446 187 0.016
germ cell development GO:0007281 185 0.016
response to steroid hormone GO:0048545 56 0.016
negative regulation of protein metabolic process GO:0051248 282 0.016
monosaccharide metabolic process GO:0005996 106 0.016
regulation of cell activation GO:0050865 289 0.015
lymphocyte proliferation GO:0046651 164 0.015
positive regulation of apoptotic signaling pathway GO:2001235 95 0.015
purine nucleoside monophosphate catabolic process GO:0009128 58 0.015
intrinsic apoptotic signaling pathway GO:0097193 132 0.015
negative regulation of immune system process GO:0002683 209 0.015
response to acid chemical GO:0001101 111 0.015
positive regulation of apoptotic process GO:0043065 217 0.015
alpha amino acid biosynthetic process GO:1901607 15 0.015
multi multicellular organism process GO:0044706 109 0.015
Mouse
cellular response to hormone stimulus GO:0032870 150 0.015
small gtpase mediated signal transduction GO:0007264 97 0.015
maintenance of location GO:0051235 89 0.014
cell maturation GO:0048469 127 0.014
cognition GO:0050890 149 0.014
cellular divalent inorganic cation homeostasis GO:0072503 127 0.014
protein ubiquitination GO:0016567 171 0.014
regulation of response to wounding GO:1903034 189 0.014
cofactor metabolic process GO:0051186 80 0.014
cellular amide metabolic process GO:0043603 58 0.014
learning or memory GO:0007611 148 0.014
positive regulation of protein phosphorylation GO:0001934 242 0.014
response to lipopolysaccharide GO:0032496 128 0.014
response to hydrogen peroxide GO:0042542 32 0.014
organelle fission GO:0048285 170 0.013
regulation of translation GO:0006417 71 0.013
striated muscle myosin thick filament assembly GO:0071688 1 0.013
positive regulation of transferase activity GO:0051347 167 0.013
epidermis development GO:0008544 187 0.013
t cell activation GO:0042110 289 0.013
cellular response to organonitrogen compound GO:0071417 145 0.013
regulation of nucleotide metabolic process GO:0006140 169 0.013
cellular protein complex assembly GO:0043623 116 0.013
tetrapyrrole metabolic process GO:0033013 22 0.013
ketone catabolic process GO:0042182 3 0.013
ribonucleotide biosynthetic process GO:0009260 59 0.013
muscle cell differentiation GO:0042692 261 0.013
cell type specific apoptotic process GO:0097285 268 0.013
carbohydrate biosynthetic process GO:0016051 74 0.013
pigment metabolic process GO:0042440 32 0.013
hexose metabolic process GO:0019318 98 0.013
striated muscle tissue development GO:0014706 293 0.013
negative regulation of cell proliferation GO:0008285 296 0.013
Mouse
cellular protein catabolic process GO:0044257 155 0.013
angiogenesis GO:0001525 201 0.013
regulation of vesicle mediated transport GO:0060627 139 0.012
ribose phosphate biosynthetic process GO:0046390 59 0.012
protein localization to organelle GO:0033365 185 0.012
Mouse
regulation of secretion by cell GO:1903530 249 0.012
negative regulation of phosphate metabolic process GO:0045936 184 0.012
regulation of homeostatic process GO:0032844 182 0.012
mitochondrial transport GO:0006839 36 0.012
nucleoside biosynthetic process GO:0009163 21 0.012
negative regulation of intracellular signal transduction GO:1902532 167 0.012
regulation of protein serine threonine kinase activity GO:0071900 157 0.012
regulation of membrane potential GO:0042391 192 0.012
regulation of inflammatory response GO:0050727 147 0.012
anion transport GO:0006820 177 0.012
organic hydroxy compound metabolic process GO:1901615 203 0.012
mitotic cell cycle GO:0000278 195 0.012
cellular calcium ion homeostasis GO:0006874 119 0.012
axonogenesis GO:0007409 274 0.012
wound healing GO:0042060 157 0.012
forebrain development GO:0030900 302 0.012
neuromuscular process GO:0050905 99 0.012
regulation of mapk cascade GO:0043408 248 0.011
skin development GO:0043588 220 0.011
regulation of generation of precursor metabolites and energy GO:0043467 38 0.011
dna metabolic process GO:0006259 303 0.011
respiratory system development GO:0060541 190 0.011
blood circulation GO:0008015 195 0.011
myosin filament assembly GO:0031034 2 0.011
xenobiotic catabolic process GO:0042178 1 0.011
ribonucleoside monophosphate catabolic process GO:0009158 57 0.011
regulation of body fluid levels GO:0050878 162 0.011
regulation of ion transmembrane transport GO:0034765 119 0.011
muscle contraction GO:0006936 101 0.011
regulation of cell motility GO:2000145 236 0.011
anatomical structure homeostasis GO:0060249 145 0.011
purine ribonucleotide biosynthetic process GO:0009152 59 0.011
cellular response to cytokine stimulus GO:0071345 189 0.011
cellular lipid metabolic process GO:0044255 323 0.011
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.011
negative regulation of transferase activity GO:0051348 85 0.011
cellular carbohydrate metabolic process GO:0044262 119 0.011
carbohydrate homeostasis GO:0033500 128 0.011
response to metal ion GO:0010038 47 0.011
Worm
extrinsic apoptotic signaling pathway GO:0097191 126 0.011
purine nucleotide biosynthetic process GO:0006164 65 0.011
nuclear transport GO:0051169 139 0.011
Mouse
water soluble vitamin biosynthetic process GO:0042364 3 0.011
cellular response to inorganic substance GO:0071241 37 0.011
skeletal muscle organ development GO:0060538 163 0.011
interleukin 8 production GO:0032637 4 0.011
urogenital system development GO:0001655 261 0.010
wnt signaling pathway GO:0016055 188 0.010
tetrapyrrole biosynthetic process GO:0033014 16 0.010
protein import GO:0017038 101 0.010
Mouse
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.010
alcohol metabolic process GO:0006066 116 0.010
multicellular organismal signaling GO:0035637 91 0.010
organic anion transport GO:0015711 137 0.010
neuron death GO:0070997 154 0.010
heme biosynthetic process GO:0006783 12 0.010
rho protein signal transduction GO:0007266 32 0.010
glucose metabolic process GO:0006006 92 0.010
regulation of transporter activity GO:0032409 57 0.010
negative regulation of kinase activity GO:0033673 81 0.010
small molecule catabolic process GO:0044282 71 0.010
protein oligomerization GO:0051259 67 0.010
myotube differentiation GO:0014902 105 0.010
epithelial cell development GO:0002064 159 0.010
regulation of peptidase activity GO:0052547 96 0.010

Prdx2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.023
nervous system disease DOID:863 0 0.023
central nervous system disease DOID:331 0 0.019
neurodegenerative disease DOID:1289 0 0.019
disease of metabolism DOID:0014667 0 0.013
inherited metabolic disorder DOID:655 0 0.013
musculoskeletal system disease DOID:17 0 0.010
connective tissue disease DOID:65 0 0.010
immune system disease DOID:2914 0 0.010
hematopoietic system disease DOID:74 0 0.010