Mus musculus

48 known processes

Krit1

KRIT1, ankyrin repeat containing

(Aliases: BB155247,2010007K12Rik,Ccm1,BB235701,AI450393,AI643869,AA432855,A630036P20Rik)

Krit1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
clathrin coat assembly GO:0048268 2 0.213
cellular response to dna damage stimulus GO:0006974 207 0.158
gene silencing GO:0016458 38 0.143
small gtpase mediated signal transduction GO:0007264 97 0.075
regulation of antigen receptor mediated signaling pathway GO:0050854 29 0.073
mirna catabolic process GO:0010587 2 0.067
cation transport GO:0006812 399 0.062
cellular nitrogen compound catabolic process GO:0044270 280 0.060
monoubiquitinated histone h2a deubiquitination GO:0035522 1 0.058
homeostasis of number of cells GO:0048872 210 0.055
multicellular organism growth GO:0035264 161 0.052
t cell receptor signaling pathway GO:0050852 46 0.052
mrna metabolic process GO:0016071 84 0.050
synaptic vesicle localization GO:0097479 59 0.049
negative regulation of gene expression epigenetic GO:0045814 15 0.047
protein modification by small protein conjugation GO:0032446 187 0.047
neural tube development GO:0021915 160 0.045
oxidation reduction process GO:0055114 342 0.045
blood circulation GO:0008015 195 0.045
regulation of ras protein signal transduction GO:0046578 114 0.044
uterus morphogenesis GO:0061038 2 0.044
leukocyte proliferation GO:0070661 172 0.044
negative regulation of germinal center formation GO:0002635 2 0.039
macromolecule methylation GO:0043414 120 0.038
meiotic nuclear division GO:0007126 115 0.037
spermatogenesis GO:0007283 284 0.037
positive regulation of protein modification process GO:0031401 299 0.034
cellular ketone metabolic process GO:0042180 84 0.034
protein modification by small protein conjugation or removal GO:0070647 207 0.033
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.033
negative regulation of glucokinase activity GO:0033132 4 0.033
cochlear nucleus development GO:0021747 4 0.033
protein modification by small protein removal GO:0070646 21 0.032
response to radiation GO:0009314 165 0.032
chromatin silencing GO:0006342 15 0.031
development of primary sexual characteristics GO:0045137 143 0.031
cellular macromolecule catabolic process GO:0044265 206 0.030
sensory organ morphogenesis GO:0090596 242 0.029
positive regulation of mapk cascade GO:0043410 170 0.029
transmembrane transport GO:0055085 412 0.029
cell junction assembly GO:0034329 52 0.029
response to light stimulus GO:0009416 135 0.029
dna metabolic process GO:0006259 303 0.028
positive regulation of protein phosphorylation GO:0001934 242 0.028
hematopoietic progenitor cell differentiation GO:0002244 143 0.027
regulation of system process GO:0044057 200 0.027
macromolecule catabolic process GO:0009057 281 0.026
regulation of lymphocyte activation GO:0051249 240 0.026
chromatin modification GO:0016568 187 0.026
histone deacetylation GO:0016575 26 0.026
neural nucleus development GO:0048857 22 0.025
rna catabolic process GO:0006401 29 0.025
regulation of adaptive immune response GO:0002819 90 0.025
negative regulation of molecular function GO:0044092 258 0.024
embryonic skeletal system development GO:0048706 120 0.024
rna splicing via transesterification reactions GO:0000375 43 0.024
protein alkylation GO:0008213 81 0.024
neural tube closure GO:0001843 90 0.024
t cell activation GO:0042110 289 0.024
lymphocyte proliferation GO:0046651 164 0.023
regulation of cell motility GO:2000145 236 0.023
Human
regulation of cellular response to stress GO:0080135 159 0.023
intracellular receptor signaling pathway GO:0030522 74 0.023
sensory perception GO:0007600 245 0.023
embryonic organ morphogenesis GO:0048562 276 0.023
regulation of t cell activation GO:0050863 170 0.023
negative regulation of immune system process GO:0002683 209 0.022
regulation of cell activation GO:0050865 289 0.022
chromatin silencing at rdna GO:0000183 3 0.022
cell cycle checkpoint GO:0000075 47 0.022
apoptotic signaling pathway GO:0097190 306 0.021
positive regulation of cellular amine metabolic process GO:0033240 5 0.021
cation transmembrane transport GO:0098655 266 0.021
intermediate filament based process GO:0045103 27 0.021
muscle system process GO:0003012 141 0.021
heart contraction GO:0060047 93 0.020
morphogenesis of embryonic epithelium GO:0016331 159 0.020
monoubiquitinated histone deubiquitination GO:0035521 1 0.020
regulation of cellular ketone metabolic process GO:0010565 66 0.020
sensory perception of sound GO:0007605 97 0.020
regulation of apoptotic signaling pathway GO:2001233 197 0.020
inner ear receptor cell development GO:0060119 39 0.020
tube formation GO:0035148 140 0.020
regulation of t cell proliferation GO:0042129 92 0.020
primary neural tube formation GO:0014020 95 0.020
adaptive immune response GO:0002250 155 0.020
heart process GO:0003015 94 0.020
histone modification GO:0016570 159 0.019
immune response activating signal transduction GO:0002757 116 0.019
organelle fission GO:0048285 170 0.019
organelle localization GO:0051640 179 0.019
regulation of transferase activity GO:0051338 263 0.018
immune response regulating signaling pathway GO:0002764 125 0.018
rho protein signal transduction GO:0007266 32 0.018
cellular amino acid metabolic process GO:0006520 103 0.018
circadian regulation of gene expression GO:0032922 48 0.018
genitalia development GO:0048806 37 0.018
ear development GO:0043583 200 0.018
establishment of synaptic vesicle localization GO:0097480 57 0.018
regulation of relaxation of muscle GO:1901077 8 0.018
regulation of transmembrane transport GO:0034762 128 0.018
sensory perception of mechanical stimulus GO:0050954 107 0.018
histone deubiquitination GO:0016578 2 0.017
spermatid differentiation GO:0048515 115 0.017
dna damage checkpoint GO:0000077 26 0.017
ear morphogenesis GO:0042471 118 0.017
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.017
sodium ion transport GO:0006814 73 0.017
negative regulation of protein metabolic process GO:0051248 282 0.017
t cell proliferation GO:0042098 120 0.017
amine metabolic process GO:0009308 45 0.016
regulation of cellular amino acid metabolic process GO:0006521 5 0.016
methylation GO:0032259 134 0.016
regulation of metal ion transport GO:0010959 106 0.016
b cell activation GO:0042113 161 0.016
learning or memory GO:0007611 148 0.016
nucleotide metabolic process GO:0009117 332 0.016
protein palmitoylation GO:0018345 14 0.016
response to peptide hormone GO:0043434 127 0.016
mitotic sister chromatid cohesion GO:0007064 1 0.016
regulation of kinase activity GO:0043549 249 0.016
heterocycle catabolic process GO:0046700 280 0.016
negative regulation of cell activation GO:0050866 111 0.016
regulation of calcium ion transport GO:0051924 69 0.015
nuclear division GO:0000280 158 0.015
heart morphogenesis GO:0003007 178 0.015
Zebrafish
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.015
camera type eye development GO:0043010 266 0.015
dna recombination GO:0006310 92 0.015
regulation of cytoskeleton organization GO:0051493 122 0.015
endocytosis GO:0006897 168 0.015
inorganic cation transmembrane transport GO:0098662 207 0.015
regulation of ion transport GO:0043269 215 0.015
positive regulation of cellular catabolic process GO:0031331 148 0.014
regulation of isoprenoid metabolic process GO:0019747 1 0.014
inner ear receptor cell differentiation GO:0060113 61 0.014
respiratory system development GO:0060541 190 0.014
tube closure GO:0060606 91 0.014
nitrogen compound transport GO:0071705 271 0.014
posttranscriptional regulation of gene expression GO:0010608 155 0.014
mitotic recombination GO:0006312 3 0.014
regulation of voltage gated calcium channel activity GO:1901385 4 0.014
organic cyclic compound catabolic process GO:1901361 295 0.014
circulatory system process GO:0003013 197 0.014
spleen development GO:0048536 39 0.014
appendage morphogenesis GO:0035107 149 0.014
respiratory tube development GO:0030323 167 0.014
cell division GO:0051301 120 0.014
face morphogenesis GO:0060325 29 0.014
negative regulation of phosphorylation GO:0042326 166 0.014
cytoplasmic mrna processing body assembly GO:0033962 6 0.014
regulation of ion transmembrane transport GO:0034765 119 0.014
maintenance of location GO:0051235 89 0.014
translesion synthesis GO:0019985 1 0.013
cellular response to organonitrogen compound GO:0071417 145 0.013
regulation of proteolysis GO:0030162 164 0.013
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.013
positive regulation of macroautophagy GO:0016239 3 0.013
immune effector process GO:0002252 321 0.013
synaptic vesicle recycling GO:0036465 19 0.013
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.013
muscle contraction GO:0006936 101 0.013
inorganic ion transmembrane transport GO:0098660 234 0.013
cellular homeostasis GO:0019725 240 0.013
organonitrogen compound biosynthetic process GO:1901566 192 0.013
establishment of rna localization GO:0051236 18 0.013
establishment of vesicle localization GO:0051650 81 0.013
coenzyme biosynthetic process GO:0009108 23 0.013
negative regulation of apoptotic signaling pathway GO:2001234 104 0.013
germ cell development GO:0007281 185 0.012
embryonic epithelial tube formation GO:0001838 130 0.012
nuclear transport GO:0051169 139 0.012
spermatid development GO:0007286 108 0.012
response to molecule of bacterial origin GO:0002237 143 0.012
response to x ray GO:0010165 11 0.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.012
cytoplasmic transport GO:0016482 234 0.012
intracellular protein transport GO:0006886 204 0.012
cellular response to lipid GO:0071396 145 0.012
positive regulation of jnk cascade GO:0046330 46 0.012
aortic valve morphogenesis GO:0003180 4 0.012
establishment of organelle localization GO:0051656 122 0.012
modification dependent macromolecule catabolic process GO:0043632 133 0.012
protein maturation GO:0051604 176 0.012
antigen receptor mediated signaling pathway GO:0050851 64 0.012
response to uv GO:0009411 44 0.011
second messenger mediated signaling GO:0019932 73 0.011
fat cell differentiation GO:0045444 160 0.011
purine ribonucleotide catabolic process GO:0009154 208 0.011
chromatin organization GO:0006325 206 0.011
neurotransmitter transport GO:0006836 76 0.011
cellular chemical homeostasis GO:0055082 215 0.011
positive regulation of cytokine production GO:0001819 174 0.011
regulation of neurotransmitter levels GO:0001505 87 0.011
regulation of protein localization GO:0032880 231 0.011
blood vessel morphogenesis GO:0048514 285 0.011
appendage development GO:0048736 166 0.011
negative regulation of adaptive immune response GO:0002820 25 0.011
intracellular steroid hormone receptor signaling pathway GO:0030518 29 0.011
synaptic transmission GO:0007268 329 0.011
negative regulation of mesenchymal cell proliferation GO:0072201 3 0.011
synaptic vesicle transport GO:0048489 57 0.011
nucleocytoplasmic transport GO:0006913 139 0.011
regulation of organelle organization GO:0033043 289 0.011
cellular amine metabolic process GO:0044106 44 0.011
vesicle coating GO:0006901 2 0.011
cognition GO:0050890 149 0.011
hair cell differentiation GO:0035315 40 0.011
regulation of high voltage gated calcium channel activity GO:1901841 2 0.011
t cell differentiation GO:0030217 174 0.011
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.011
exocytosis GO:0006887 121 0.011
cellular response to abiotic stimulus GO:0071214 56 0.011
regulation of lymphocyte proliferation GO:0050670 117 0.010
nucleobase containing small molecule metabolic process GO:0055086 352 0.010
ion transmembrane transport GO:0034220 361 0.010
regulation of protein kinase activity GO:0045859 232 0.010
aromatic compound catabolic process GO:0019439 286 0.010
protein methylation GO:0006479 81 0.010
regulation of b cell activation GO:0050864 81 0.010
dna repair GO:0006281 107 0.010
response to organic cyclic compound GO:0014070 198 0.010
cardiac muscle contraction GO:0060048 32 0.010
negative regulation of cellular protein metabolic process GO:0032269 247 0.010
positive regulation of cell division GO:0051781 31 0.010
cell chemotaxis GO:0060326 81 0.010

Krit1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.011
musculoskeletal system disease DOID:17 0 0.011
connective tissue disease DOID:65 0 0.011
cancer DOID:162 0 0.010
disease of cellular proliferation DOID:14566 0 0.010
organ system cancer DOID:0050686 0 0.010