Mus musculus

113 known processes

Pitx1

paired-like homeodomain transcription factor 1

(Aliases: Ptx1,P-OTX,Potx,Bft)

Pitx1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
limb development GO:0060173 166 0.999
forebrain neuron fate commitment GO:0021877 13 0.999
embryonic skeletal system development GO:0048706 120 0.999
endodermal cell fate specification GO:0001714 4 0.998
appendage morphogenesis GO:0035107 149 0.998
positive regulation of secondary heart field cardioblast proliferation GO:0072513 4 0.997
commitment of neuronal cell to specific neuron type in forebrain GO:0021902 7 0.997
regulation of canonical wnt signaling pathway GO:0060828 82 0.997
embryonic skeletal system morphogenesis GO:0048704 91 0.997
positive regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiation GO:0003257 3 0.996
visceral motor neuron differentiation GO:0021524 3 0.996
cardiac chamber morphogenesis GO:0003206 93 0.995
Mouse
spinal cord motor neuron differentiation GO:0021522 35 0.995
bundle of his development GO:0003166 4 0.995
sinoatrial node cell differentiation GO:0060921 3 0.994
negative regulation of cardiac chamber morphogenesis GO:1901220 2 0.994
limb morphogenesis GO:0035108 149 0.993
pituitary gland development GO:0021983 38 0.992
his purkinje system cell differentiation GO:0060932 2 0.992
forebrain development GO:0030900 302 0.992
skeletal system morphogenesis GO:0048705 203 0.991
his purkinje system development GO:0003164 4 0.989
alpha beta t cell differentiation GO:0046632 69 0.989
mesenchymal cell proliferation GO:0010463 44 0.989
hindlimb morphogenesis GO:0035137 42 0.989
embryonic appendage morphogenesis GO:0035113 126 0.987
embryonic organ morphogenesis GO:0048562 276 0.986
Mouse
specification of organ position GO:0010159 3 0.986
mesenchymal cell proliferation involved in ureter development GO:0072198 4 0.985
forebrain generation of neurons GO:0021872 63 0.985
diencephalon development GO:0021536 63 0.985
skeletal system development GO:0001501 356 0.984
forebrain neuron differentiation GO:0021879 52 0.983
digestive tract morphogenesis GO:0048546 147 0.983
Mouse
mammary placode formation GO:0060596 4 0.983
regulation of skeletal muscle fiber differentiation GO:1902809 3 0.982
positive regulation of transcription from rna polymerase ii promoter involved in heart development GO:1901228 4 0.982
positive regulation of myotube differentiation GO:0010831 24 0.981
endodermal cell fate commitment GO:0001711 12 0.981
gastrulation GO:0007369 116 0.980
cell differentiation involved in embryonic placenta development GO:0060706 26 0.979
mesodermal to mesenchymal transition involved in gastrulation GO:0060809 1 0.978
cardiac chamber development GO:0003205 108 0.978
Mouse
epidermis development GO:0008544 187 0.978
negative regulation of wnt signaling pathway GO:0030178 73 0.978
outflow tract morphogenesis GO:0003151 53 0.978
Mouse
primary neural tube formation GO:0014020 95 0.977
closure of optic fissure GO:0061386 2 0.975
pancreatic pp cell fate commitment GO:0003329 2 0.974
central nervous system neuron differentiation GO:0021953 162 0.972
autonomic nervous system development GO:0048483 43 0.972
forebrain regionalization GO:0021871 25 0.971
positive regulation of stem cell proliferation GO:2000648 59 0.970
embryonic hindlimb morphogenesis GO:0035116 32 0.969
cardiac neural crest cell migration involved in outflow tract morphogenesis GO:0003253 3 0.969
Mouse
forelimb morphogenesis GO:0035136 40 0.969
morphogenesis of embryonic epithelium GO:0016331 159 0.968
vagus nerve development GO:0021564 3 0.968
palate development GO:0060021 76 0.967
mesenchyme development GO:0060485 152 0.967
Mouse
cerebral cortex neuron differentiation GO:0021895 19 0.965
heart formation GO:0060914 16 0.965
olfactory lobe development GO:0021988 32 0.964
cardiac septum morphogenesis GO:0060411 46 0.964
Mouse
atrioventricular bundle cell differentiation GO:0003167 1 0.963
regulation of organ morphogenesis GO:2000027 144 0.963
wnt signaling pathway GO:0016055 188 0.961
Mouse
regulation of wnt signaling pathway GO:0030111 123 0.961
embryonic eye morphogenesis GO:0048048 29 0.960
skeletal muscle cell differentiation GO:0035914 66 0.960
enamel mineralization GO:0070166 7 0.959
embryonic digit morphogenesis GO:0042733 56 0.959
embryonic epithelial tube formation GO:0001838 130 0.958
heart valve morphogenesis GO:0003179 21 0.958
ventral spinal cord development GO:0021517 48 0.957
middle ear morphogenesis GO:0042474 23 0.957
regulation of tongue muscle cell differentiation GO:2001035 2 0.957
bmp signaling pathway GO:0030509 93 0.956
cell fate specification GO:0001708 72 0.954
camera type eye development GO:0043010 266 0.953
Mouse
endocrine system development GO:0035270 98 0.953
olfactory bulb development GO:0021772 30 0.952
cellular response to acid chemical GO:0071229 68 0.952
endocardial cushion morphogenesis GO:0003203 18 0.952
limbic system development GO:0021761 72 0.951
Mouse
mesenchymal cell development GO:0014031 93 0.950
Mouse
sensory organ morphogenesis GO:0090596 242 0.949
Mouse
tube formation GO:0035148 140 0.948
notochord formation GO:0014028 5 0.946
neural tube closure GO:0001843 90 0.945
myoblast differentiation GO:0045445 52 0.941
regulation of cardiac chamber morphogenesis GO:1901219 2 0.938
canonical wnt signaling pathway GO:0060070 130 0.938
positive regulation of mesenchymal cell proliferation involved in ureter development GO:2000729 3 0.936
skin development GO:0043588 220 0.935
regulation of cardioblast differentiation GO:0051890 3 0.934
cardiac ventricle formation GO:0003211 8 0.933
positive regulation of striated muscle cell differentiation GO:0051155 35 0.932
embryonic heart tube morphogenesis GO:0003143 51 0.931
positive regulation of auditory receptor cell differentiation GO:0045609 1 0.930
regulation of heart looping GO:1901207 1 0.930
cardiac muscle tissue morphogenesis GO:0055008 44 0.929
Mouse
tongue development GO:0043586 18 0.928
embryonic forelimb morphogenesis GO:0035115 32 0.927
pericardium development GO:0060039 16 0.926
regulation of cardiac chamber formation GO:1901210 1 0.926
neural tube development GO:0021915 160 0.924
epithelial tube morphogenesis GO:0060562 303 0.922
Mouse
cellular response to lipid GO:0071396 145 0.921
digestive tract development GO:0048565 190 0.921
Mouse
telencephalon regionalization GO:0021978 14 0.920
lung development GO:0030324 164 0.918
Mouse
trophectodermal cell differentiation GO:0001829 21 0.918
heart morphogenesis GO:0003007 178 0.918
Mouse
positive regulation of skeletal muscle fiber differentiation GO:1902811 2 0.918
negative regulation of canonical wnt signaling pathway GO:0090090 51 0.916
pallium development GO:0021543 120 0.915
cell fate commitment GO:0045165 210 0.915
neuron migration GO:0001764 122 0.915
Mouse
pulmonary valve formation GO:0003193 1 0.914
regulation of embryonic development GO:0045995 71 0.914
myotube differentiation GO:0014902 105 0.913
Mouse
regulation of canonical wnt signaling pathway involved in neural plate anterior posterior pattern formation GO:0060827 1 0.911
mammary gland morphogenesis GO:0060443 54 0.911
formation of primary germ layer GO:0001704 77 0.910
odontogenesis of dentin containing tooth GO:0042475 66 0.909
cardiocyte differentiation GO:0035051 87 0.909
Mouse
morphogenesis of an epithelial sheet GO:0002011 27 0.907
telencephalon development GO:0021537 186 0.907
positive regulation of skeletal muscle cell differentiation GO:2001016 4 0.907
regulation of neuron projection development GO:0010975 169 0.906
muscle tissue morphogenesis GO:0060415 53 0.905
Mouse
heart valve formation GO:0003188 10 0.900
cardiac chamber formation GO:0003207 10 0.898
cardiac septum development GO:0003279 59 0.896
Mouse
paraxial mesodermal cell fate commitment GO:0048343 2 0.894
regulation of mesenchymal cell proliferation GO:0010464 37 0.894
heart valve development GO:0003170 23 0.893
Mouse
head morphogenesis GO:0060323 34 0.892
atrial cardiac muscle cell differentiation GO:0055011 2 0.892
ear morphogenesis GO:0042471 118 0.892
embryonic placenta development GO:0001892 98 0.892
cerebral cortex development GO:0021987 86 0.890
positive regulation of mesenchymal cell proliferation GO:0002053 33 0.888
ear development GO:0043583 200 0.884
ventricular septum morphogenesis GO:0060412 27 0.884
Mouse
regulation of mesenchymal cell proliferation involved in ureter development GO:0072199 3 0.884
regulation of heart morphogenesis GO:2000826 22 0.882
neural tube formation GO:0001841 108 0.876
tube closure GO:0060606 91 0.876
regulation of cell motility GO:2000145 236 0.875
Mouse
pharynx development GO:0060465 1 0.874
embryonic heart tube development GO:0035050 65 0.872
cytokine production GO:0001816 319 0.870
regulation of myotube differentiation GO:0010830 62 0.869
determination of heart left right asymmetry GO:0061371 48 0.869
regulation of muscle tissue development GO:1901861 97 0.866
neural crest cell development GO:0014032 48 0.861
Mouse
aorta morphogenesis GO:0035909 22 0.860
developmental maturation GO:0021700 193 0.857
positive regulation of heart growth GO:0060421 18 0.857
cardiac muscle cell fate commitment GO:0060923 6 0.855
cell differentiation in spinal cord GO:0021515 53 0.855
positive regulation of transcription via serum response element binding GO:0010735 1 0.854
negative regulation of heart looping GO:1901208 1 0.854
carbon catabolite repression of transcription from rna polymerase ii promoter GO:0000437 1 0.853
negative regulation of cardiac chamber formation GO:1901211 1 0.853
globus pallidus development GO:0021759 2 0.852
cardiac left ventricle formation GO:0003218 1 0.851
positive regulation of tongue muscle cell differentiation GO:2001037 2 0.849
specification of organ identity GO:0010092 30 0.849
ventral spinal cord interneuron differentiation GO:0021514 16 0.847
regulation of stem cell proliferation GO:0072091 78 0.847
spinal cord development GO:0021510 81 0.844
clara cell differentiation GO:0060486 4 0.840
vagus nerve morphogenesis GO:0021644 2 0.839
hindbrain development GO:0030902 128 0.839
tongue morphogenesis GO:0043587 8 0.838
embryonic camera type eye development GO:0031076 36 0.838
Mouse
gland development GO:0048732 330 0.838
regulation of mesenchymal cell apoptotic process GO:2001053 14 0.837
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000802 1 0.836
placenta development GO:0001890 140 0.835
positive regulation of inner ear receptor cell differentiation GO:2000982 1 0.835
endocardial cushion formation GO:0003272 13 0.834
embryonic limb morphogenesis GO:0030326 126 0.833
determination of left right symmetry GO:0007368 80 0.833
Mouse
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis GO:0061350 2 0.831
positive regulation of cardioblast differentiation GO:0051891 3 0.830
negative regulation of canonical wnt signaling pathway involved in neural plate anterior posterior pattern formation GO:0060829 1 0.829
stem cell differentiation GO:0048863 268 0.827
Mouse
tricuspid valve development GO:0003175 3 0.826
pancreatic a cell fate commitment GO:0003326 2 0.826
segmentation GO:0035282 93 0.824
mammary gland epithelium development GO:0061180 65 0.822
mesenchyme morphogenesis GO:0072132 32 0.820
endocardial cushion to mesenchymal transition involved in heart valve formation GO:0003199 4 0.819
muscle cell fate commitment GO:0042693 11 0.818
cartilage development GO:0051216 140 0.816
cardiac conduction system development GO:0003161 12 0.815
bone morphogenesis GO:0060349 78 0.815
bone development GO:0060348 120 0.813
Mouse
striated muscle tissue development GO:0014706 293 0.813
auditory receptor cell fate determination GO:0042668 3 0.812
preganglionic parasympathetic nervous system development GO:0021783 17 0.810
atrial cardiac muscle cell development GO:0055014 2 0.809
branching involved in mammary gland duct morphogenesis GO:0060444 27 0.808
morphogenesis of a branching epithelium GO:0061138 193 0.807
Mouse
appendage development GO:0048736 166 0.806
mesoderm formation GO:0001707 62 0.804
mitral valve morphogenesis GO:0003183 4 0.801
alpha beta t cell activation GO:0046631 91 0.799
somite rostral caudal axis specification GO:0032525 13 0.798
auditory receptor cell fate specification GO:0042667 1 0.798
regulation of cardioblast proliferation GO:0003264 9 0.797
regulation of cardiac muscle tissue growth GO:0055021 26 0.796
striated muscle cell proliferation GO:0014855 39 0.793
cardiac muscle cell development GO:0055013 39 0.791
Mouse
dorsal ventral axon guidance GO:0033563 3 0.791
Worm
t cell activation GO:0042110 289 0.790
sinoatrial node development GO:0003163 4 0.789
t cell differentiation GO:0030217 174 0.789
hemangioblast cell differentiation GO:0060217 1 0.788
regulation of organ formation GO:0003156 34 0.787
mammary gland duct morphogenesis GO:0060603 38 0.785
positive regulation of cardiac muscle tissue growth GO:0055023 15 0.781
social behavior GO:0035176 21 0.780
regulation of chondrocyte differentiation GO:0032330 33 0.779
positive regulation of transcription from rna polymerase ii promoter involved in norepinephrine biosynthetic process GO:2000763 1 0.772
regulation of striated muscle cell differentiation GO:0051153 81 0.770
mesodermal cell migration GO:0008078 4 0.769
face morphogenesis GO:0060325 29 0.768
cellular response to retinoic acid GO:0071300 25 0.768
canonical wnt signaling pathway involved in neural plate anterior posterior pattern formation GO:0060823 1 0.767
mitral valve development GO:0003174 4 0.764
inner ear morphogenesis GO:0042472 101 0.763
leukocyte differentiation GO:0002521 342 0.761
aortic valve development GO:0003176 5 0.758
regionalization GO:0003002 337 0.758
Mouse
mesoderm morphogenesis GO:0048332 64 0.756
spinal cord oligodendrocyte cell fate specification GO:0021530 3 0.756
positive regulation of muscle tissue development GO:1901863 32 0.755
tongue muscle cell differentiation GO:0035981 2 0.755
parasympathetic nervous system development GO:0048486 19 0.754
b cell activation GO:0042113 161 0.754
ventricular cardiac myofibril assembly GO:0055005 3 0.749
lymphocyte activation involved in immune response GO:0002285 93 0.747
embryonic heart tube formation GO:0003144 1 0.746
regulation of cardiac muscle cell proliferation GO:0060043 23 0.745
positive regulation of muscle cell differentiation GO:0051149 39 0.743
cell proliferation involved in heart morphogenesis GO:0061323 15 0.742
Mouse
somitogenesis GO:0001756 69 0.741
planar cell polarity pathway involved in pericardium morphogenesis GO:0061354 2 0.734
outflow tract septum morphogenesis GO:0003148 11 0.733
positive regulation of striated muscle tissue development GO:0045844 31 0.733
regulation of transcription from rna polymerase ii promoter involved in heart development GO:1901213 9 0.730
lymphocyte differentiation GO:0030098 242 0.727
intracellular receptor signaling pathway GO:0030522 74 0.723
muscle cell differentiation GO:0042692 261 0.723
male sex differentiation GO:0046661 109 0.719
mesenchymal cell differentiation GO:0048762 107 0.716
Mouse
blood vessel morphogenesis GO:0048514 285 0.706
Mouse
cerebral cortex regionalization GO:0021796 8 0.703
negative regulation of neuron differentiation GO:0045665 101 0.700
pancreatic pp cell differentiation GO:0003312 2 0.699
pyramidal neuron migration GO:0021852 1 0.699
semicircular canal development GO:0060872 9 0.698
cardioblast proliferation GO:0003263 8 0.696
epithelial to mesenchymal transition GO:0001837 47 0.695
thyroid stimulating hormone secreting cell differentiation GO:0060129 4 0.695
paraxial mesodermal cell differentiation GO:0048342 2 0.693
endoderm formation GO:0001706 20 0.692
response to fibroblast growth factor GO:0071774 47 0.688
stem cell maintenance GO:0019827 130 0.684
negative regulation of mesenchymal cell apoptotic process GO:2001054 11 0.681
coronary artery morphogenesis GO:0060982 6 0.681
retina morphogenesis in camera type eye GO:0060042 45 0.679
sinoatrial node cell development GO:0060931 3 0.679
cardiac pacemaker cell development GO:0060926 5 0.678
mesoderm development GO:0007498 100 0.677
negative regulation of nervous system development GO:0051961 156 0.676
somatic cell dna recombination GO:0016444 51 0.674
regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiation GO:0003256 6 0.674
regulation of auditory receptor cell differentiation GO:0045607 4 0.673
smad protein signal transduction GO:0060395 21 0.672
stem cell proliferation GO:0072089 117 0.671
cardiac muscle tissue development GO:0048738 130 0.668
Mouse
cardiac atrium development GO:0003230 24 0.666
Mouse
myeloid cell differentiation GO:0030099 233 0.665
positive regulation of neuron differentiation GO:0045666 141 0.664
male gamete generation GO:0048232 285 0.663
regulation of cardiac muscle tissue development GO:0055024 31 0.662
regulation of b cell mediated immunity GO:0002712 37 0.662
neuron projection guidance GO:0097485 141 0.661
Worm
regulation of smad protein complex assembly GO:0010990 1 0.659
cardiac cell fate commitment GO:0060911 10 0.658
blastocyst development GO:0001824 80 0.657
atrial septum development GO:0003283 12 0.657
t cell activation involved in immune response GO:0002286 43 0.656
atrioventricular valve development GO:0003171 15 0.656
Mouse
epithelial tube formation GO:0072175 130 0.656
ventricular septum development GO:0003281 42 0.653
Mouse
cerebral cortex gabaergic interneuron differentiation GO:0021892 9 0.648
negative regulation of epithelial cell proliferation GO:0050680 64 0.646
cell proliferation in hindbrain GO:0021534 10 0.645
regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000800 1 0.645
tooth mineralization GO:0034505 9 0.644
negative regulation of cell development GO:0010721 169 0.643
aortic valve morphogenesis GO:0003180 4 0.642
embryonic axis specification GO:0000578 30 0.642
positive regulation of epithelial cell proliferation GO:0050679 68 0.641
angiogenesis GO:0001525 201 0.640
Mouse
hair follicle morphogenesis GO:0031069 29 0.638
renal vesicle induction GO:0072034 3 0.638
leukocyte activation involved in immune response GO:0002366 126 0.633
otic vesicle development GO:0071599 14 0.633
muscle fiber development GO:0048747 76 0.631
cardiac muscle cell myoblast differentiation GO:0060379 8 0.630
wnt signaling pathway involved in forebrain neuroblast division GO:0021874 2 0.630
cardiac ventricle morphogenesis GO:0003208 50 0.626
developmental growth involved in morphogenesis GO:0060560 138 0.624
cd8 positive alpha beta t cell differentiation GO:0043374 9 0.621
motor neuron migration GO:0097475 4 0.619
negative regulation of gastrulation GO:2000542 3 0.618
positive regulation of cell activation GO:0050867 158 0.618
regulation of neuron differentiation GO:0045664 281 0.618
cardiac muscle cell differentiation GO:0055007 69 0.617
Mouse
lung cell differentiation GO:0060479 30 0.617
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.616
positive regulation of isotype switching to igg isotypes GO:0048304 7 0.614
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.613
cell migration involved in gastrulation GO:0042074 13 0.613
ventricular cardiac muscle tissue development GO:0003229 38 0.610
regulation of myoblast differentiation GO:0045661 29 0.609
blood vessel remodeling GO:0001974 33 0.608
metanephric nephron tubule formation GO:0072289 4 0.607
epithelial cell fate commitment GO:0072148 13 0.605
regulation of cell proliferation involved in heart morphogenesis GO:2000136 15 0.603
cardiac pacemaker cell fate commitment GO:0060927 1 0.600
positive regulation of skeletal muscle tissue regeneration GO:0043415 4 0.598
blastocyst formation GO:0001825 33 0.598
pulmonary valve development GO:0003177 5 0.598
regulation of cell activation GO:0050865 289 0.598
semicircular canal morphogenesis GO:0048752 7 0.594
cartilage morphogenesis GO:0060536 11 0.592
t cell differentiation involved in immune response GO:0002292 30 0.591
negative regulation of cell fate specification GO:0009996 4 0.591
regulation of erythrocyte differentiation GO:0045646 23 0.588
positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060501 3 0.587
trachea cartilage morphogenesis GO:0060535 4 0.586
cardioblast differentiation GO:0010002 13 0.584
cardiac muscle cell proliferation GO:0060038 31 0.578
atrioventricular valve morphogenesis GO:0003181 13 0.578
somatic diversification of immunoglobulins involved in immune response GO:0002208 36 0.577
branchiomeric skeletal muscle development GO:0014707 3 0.571
regulation of lymphocyte activation GO:0051249 240 0.571
cell proliferation involved in outflow tract morphogenesis GO:0061325 4 0.569
Mouse
retinal bipolar neuron differentiation GO:0060040 5 0.568
myeloid leukocyte differentiation GO:0002573 119 0.561
atrioventricular node cell development GO:0060928 2 0.559
digestive system development GO:0055123 200 0.557
Mouse
regulation of heart growth GO:0060420 31 0.556
atrioventricular node cell differentiation GO:0060922 2 0.555
purkinje myocyte differentiation GO:0003168 1 0.555
cell activation involved in immune response GO:0002263 126 0.554
gastrulation with mouth forming second GO:0001702 29 0.551
cell maturation GO:0048469 127 0.551
neural plate morphogenesis GO:0001839 9 0.551
post anal tail morphogenesis GO:0036342 23 0.550
chondrocyte differentiation GO:0002062 72 0.549
ureter development GO:0072189 12 0.548
regulation of skeletal muscle cell differentiation GO:2001014 11 0.547
germ line sex determination GO:0018992 3 0.546
primary prostatic bud elongation GO:0060516 2 0.546
chromatin modification GO:0016568 187 0.546
cranial nerve morphogenesis GO:0021602 26 0.545
cardiac atrium morphogenesis GO:0003209 23 0.542
Mouse
lung epithelium development GO:0060428 37 0.541
regulation of binding GO:0051098 111 0.540
Mouse
b cell activation involved in immune response GO:0002312 50 0.540
germ cell development GO:0007281 185 0.537
embryonic heart tube left right pattern formation GO:0060971 5 0.533
artery development GO:0060840 53 0.529
midbrain hindbrain boundary maturation GO:0021732 1 0.526
connective tissue development GO:0061448 179 0.523
planar cell polarity pathway involved in cardiac right atrium morphogenesis GO:0061349 2 0.521
nephric duct formation GO:0072179 4 0.519
tissue remodeling GO:0048771 102 0.519
dna metabolic process GO:0006259 303 0.517
fat cell differentiation GO:0045444 160 0.517
regulation of epidermal cell differentiation GO:0045604 21 0.517
muscle cell development GO:0055001 133 0.514
Mouse
regulation of epithelial cell proliferation GO:0050678 141 0.513
regulation of adaptive immune response GO:0002819 90 0.512
negative regulation of myeloid cell differentiation GO:0045638 38 0.511
regulation of cardiac cell fate specification GO:2000043 1 0.510
morphogenesis of a branching structure GO:0001763 203 0.506
Mouse
skeletal muscle fiber differentiation GO:0098528 5 0.500
epithelial cell development GO:0002064 159 0.498
carbon catabolite activation of transcription from rna polymerase ii promoter GO:0000436 4 0.497
erythrocyte differentiation GO:0030218 88 0.496
retinoic acid receptor signaling pathway GO:0048384 17 0.496
deltoid tuberosity development GO:0035993 3 0.494
Mouse
cardiac cell fate determination GO:0060913 2 0.493
nerve development GO:0021675 67 0.493
atrioventricular canal development GO:0036302 5 0.492
regulation of fat cell differentiation GO:0045598 81 0.492
spinal cord motor neuron cell fate specification GO:0021520 13 0.489
midbrain development GO:0030901 35 0.488
Mouse
regulation of secondary heart field cardioblast proliferation GO:0003266 9 0.488
otic vesicle morphogenesis GO:0071600 10 0.486
cochlea morphogenesis GO:0090103 22 0.486
sensory perception of mechanical stimulus GO:0050954 107 0.483
negative regulation of embryonic development GO:0045992 22 0.481
cell fate determination GO:0001709 32 0.478
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 51 0.477
somite development GO:0061053 81 0.476
positive regulation of cardiac muscle tissue development GO:0055025 19 0.474
intermediate filament cytoskeleton organization GO:0045104 26 0.471
regulation of b cell activation GO:0050864 81 0.470
regulation of isotype switching GO:0045191 22 0.469
regulation of stem cell differentiation GO:2000736 50 0.469
cerebral cortex cell migration GO:0021795 44 0.467
positive regulation of protein phosphorylation GO:0001934 242 0.465
positive regulation of cardiac muscle cell proliferation GO:0060045 15 0.463
cardiac neural crest cell development involved in heart development GO:0061308 7 0.462
Mouse
skeletal muscle fiber development GO:0048741 58 0.459
epithelial cell proliferation GO:0050673 174 0.456
positive regulation of stem cell differentiation GO:2000738 23 0.456
urogenital system development GO:0001655 261 0.456
odontogenesis GO:0042476 78 0.456
Mouse
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.455
axis elongation involved in somitogenesis GO:0090245 4 0.455
cd8 positive alpha beta t cell activation GO:0036037 9 0.453
ventral spinal cord interneuron fate determination GO:0060580 1 0.453
regulation of skeletal muscle fiber development GO:0048742 36 0.452
regulation of cartilage development GO:0061035 44 0.451
tissue migration GO:0090130 68 0.451
neuron fate specification GO:0048665 30 0.442
glial cell differentiation GO:0010001 131 0.440
glandular epithelial cell differentiation GO:0002067 38 0.437
ectodermal placode morphogenesis GO:0071697 16 0.432
atrioventricular node cell fate commitment GO:0060929 1 0.431
regulation of bmp signaling pathway GO:0030510 60 0.429
endocardial cushion development GO:0003197 26 0.429
mesenchymal cell apoptotic process GO:0097152 14 0.428
cellular protein complex assembly GO:0043623 116 0.427
pharyngeal system development GO:0060037 17 0.426
semaphorin plexin signaling pathway involved in outflow tract morphogenesis GO:0071527 1 0.426
regulation of voltage gated calcium channel activity GO:1901385 4 0.425
regulation of morphogenesis of a branching structure GO:0060688 53 0.424
cellular response to fibroblast growth factor stimulus GO:0044344 47 0.422
interferon gamma production GO:0032609 67 0.421
forebrain neuron development GO:0021884 30 0.421
axon guidance GO:0007411 141 0.420
Worm
ameboidal type cell migration GO:0001667 128 0.419
Mouse
ventricular cardiac muscle tissue morphogenesis GO:0055010 32 0.419
ossification GO:0001503 216 0.418
stem cell development GO:0048864 219 0.417
Mouse
positive regulation of nervous system development GO:0051962 221 0.415
septum primum development GO:0003284 4 0.413
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.408
hypophysis morphogenesis GO:0048850 3 0.406
chemotaxis GO:0006935 247 0.405
Worm
cardiac right ventricle formation GO:0003219 3 0.403
gliogenesis GO:0042063 141 0.401
organ growth GO:0035265 117 0.401
positive regulation of immunoglobulin production GO:0002639 28 0.400
epidermis morphogenesis GO:0048730 33 0.395
face development GO:0060324 38 0.391
negative regulation of smad protein complex assembly GO:0010991 1 0.391
regulation of branching involved in salivary gland morphogenesis GO:0060693 11 0.390
epithelial cell morphogenesis GO:0003382 41 0.389
body morphogenesis GO:0010171 45 0.388
sensory perception of sound GO:0007605 97 0.385
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.385
coronary vasculature morphogenesis GO:0060977 9 0.384
positive regulation of production of molecular mediator of immune response GO:0002702 45 0.383
endocrine pancreas development GO:0031018 29 0.381
positive regulation of mechanoreceptor differentiation GO:0045633 1 0.380
positive regulation of keratinocyte proliferation GO:0010838 4 0.372
branching morphogenesis of an epithelial tube GO:0048754 159 0.369
Mouse
hematopoietic progenitor cell differentiation GO:0002244 143 0.369
regulation of cell projection organization GO:0031344 206 0.368
muscle system process GO:0003012 141 0.367
spinal cord motor neuron migration GO:0097476 4 0.366
central nervous system vasculogenesis GO:0022009 3 0.362
nephron tubule formation GO:0072079 20 0.362
regulation of response to wounding GO:1903034 189 0.361
embryonic digestive tract morphogenesis GO:0048557 17 0.360
Mouse
lymphocyte migration GO:0072676 26 0.359
lateral motor column neuron migration GO:0097477 3 0.358
endodermal cell fate determination GO:0007493 2 0.355
respiratory system development GO:0060541 190 0.354
Mouse
noradrenergic neuron differentiation GO:0003357 6 0.354
negative regulation of ossification GO:0030279 49 0.352
negative regulation of cell proliferation GO:0008285 296 0.351
coronary vasculature development GO:0060976 12 0.351
cell aging GO:0007569 35 0.349
cell fate specification involved in pattern specification GO:0060573 11 0.349

Pitx1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org