Mus musculus

235 known processes

Park2

Parkinson disease (autosomal recessive, juvenile) 2, parkin

(Aliases: MGC130518,PRKN)

Park2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
transmembrane transport GO:0055085 412 0.716
locomotory behavior GO:0007626 195 0.596
membrane organization GO:0061024 245 0.522
Human Worm Fly
adult behavior GO:0030534 135 0.492
cation transport GO:0006812 399 0.475
regulation of membrane potential GO:0042391 192 0.446
synaptic transmission GO:0007268 329 0.380
ion transmembrane transport GO:0034220 361 0.379
cellular lipid metabolic process GO:0044255 323 0.379
apoptotic signaling pathway GO:0097190 306 0.377
regulation of neurotransmitter transport GO:0051588 35 0.349
apoptotic mitochondrial changes GO:0008637 48 0.330
Human
mitochondrion organization GO:0007005 134 0.327
Human Fly
regulation of neurotransmitter secretion GO:0046928 29 0.315
regulation of secretion by cell GO:1903530 249 0.290
adult locomotory behavior GO:0008344 91 0.280
spermatid differentiation GO:0048515 115 0.276
organic cyclic compound catabolic process GO:1901361 295 0.262
response to reactive oxygen species GO:0000302 56 0.258
response to oxidative stress GO:0006979 123 0.251
sensory perception GO:0007600 245 0.246
cation transmembrane transport GO:0098655 266 0.241
regulation of ion transmembrane transport GO:0034765 119 0.240
nucleotide metabolic process GO:0009117 332 0.238
dopamine metabolic process GO:0042417 23 0.227
cellular response to organonitrogen compound GO:0071417 145 0.217
positive regulation of mitochondrion organization GO:0010822 17 0.217
Human Fly
divalent metal ion transport GO:0070838 172 0.213
regulation of ion transport GO:0043269 215 0.213
regulation of protein localization GO:0032880 231 0.207
inorganic ion transmembrane transport GO:0098660 234 0.206
regulation of ion transmembrane transporter activity GO:0032412 54 0.202
response to organonitrogen compound GO:0010243 246 0.201
spermatogenesis GO:0007283 284 0.198
Fly
regulation of cellular amine metabolic process GO:0033238 20 0.189
macromolecule catabolic process GO:0009057 281 0.178
regulation of mitochondrion organization GO:0010821 27 0.178
Human Fly
multicellular organismal signaling GO:0035637 91 0.175
response to light stimulus GO:0009416 135 0.166
regulation of cellular catabolic process GO:0031329 242 0.164
purine nucleotide metabolic process GO:0006163 302 0.163
regulation of systemic arterial blood pressure GO:0003073 61 0.156
positive regulation of voltage gated calcium channel activity GO:1901387 2 0.156
carboxylic acid transport GO:0046942 100 0.149
regulation of canonical wnt signaling pathway GO:0060828 82 0.149
organic hydroxy compound metabolic process GO:1901615 203 0.147
response to radiation GO:0009314 165 0.141
neurotransmitter secretion GO:0007269 62 0.141
cell cell signaling involved in lung development GO:0060495 1 0.137
endomembrane system organization GO:0010256 147 0.137
purine nucleoside metabolic process GO:0042278 241 0.133
regulation of metal ion transport GO:0010959 106 0.132
regulation of apoptotic signaling pathway GO:2001233 197 0.127
regulation of blood circulation GO:1903522 93 0.126
transmission of nerve impulse GO:0019226 76 0.125
amine metabolic process GO:0009308 45 0.124
organophosphate catabolic process GO:0046434 232 0.123
establishment of organelle localization GO:0051656 122 0.122
inclusion body assembly GO:0070841 3 0.119
Human
positive regulation of protein modification process GO:0031401 299 0.112
nucleoside catabolic process GO:0009164 206 0.109
response to extracellular stimulus GO:0009991 127 0.108
circulatory system process GO:0003013 197 0.106
positive regulation of kinase activity GO:0033674 155 0.105
cellular response to oxidative stress GO:0034599 76 0.104
regulation of transferase activity GO:0051338 263 0.103
Human
regulation of endocytosis GO:0030100 69 0.102
Worm
nucleoside phosphate catabolic process GO:1901292 222 0.101
calcium ion transmembrane transport GO:0070588 85 0.099
inorganic cation transmembrane transport GO:0098662 207 0.098
cardiac muscle contraction GO:0060048 32 0.097
learning or memory GO:0007611 148 0.096
regulation of secretion GO:0051046 274 0.096
neuronal action potential GO:0019228 54 0.095
nucleobase containing small molecule metabolic process GO:0055086 352 0.095
establishment of protein localization to organelle GO:0072594 118 0.094
ribonucleotide metabolic process GO:0009259 291 0.094
divalent inorganic cation transport GO:0072511 178 0.093
cellular ketone metabolic process GO:0042180 84 0.093
organic acid transport GO:0015849 101 0.092
nucleoside metabolic process GO:0009116 246 0.091
cation homeostasis GO:0055080 212 0.091
Fly
nucleotide catabolic process GO:0009166 217 0.091
gland development GO:0048732 330 0.091
establishment of vesicle localization GO:0051650 81 0.091
muscle system process GO:0003012 141 0.089
g protein coupled receptor signaling pathway GO:0007186 243 0.088
regulation of g protein activated inward rectifier potassium channel activity GO:1900128 1 0.087
nucleocytoplasmic transport GO:0006913 139 0.087
protein maturation GO:0051604 176 0.086
cellular response to growth factor stimulus GO:0071363 197 0.086
sodium ion transport GO:0006814 73 0.085
synaptic vesicle localization GO:0097479 59 0.085
organic anion transport GO:0015711 137 0.084
regulation of voltage gated calcium channel activity GO:1901385 4 0.083
anion transport GO:0006820 177 0.083
cofactor metabolic process GO:0051186 80 0.082
regulation of transmembrane transport GO:0034762 128 0.081
nucleoside phosphate metabolic process GO:0006753 338 0.080
purine containing compound metabolic process GO:0072521 311 0.079
male gamete generation GO:0048232 285 0.079
Fly
protein import into nucleus GO:0006606 95 0.079
regulation of hydrolase activity GO:0051336 246 0.077
cellular amine metabolic process GO:0044106 44 0.077
ribose phosphate metabolic process GO:0019693 291 0.077
positive regulation of transferase activity GO:0051347 167 0.077
protein catabolic process GO:0030163 221 0.076
cytoplasmic transport GO:0016482 234 0.076
heterocycle catabolic process GO:0046700 280 0.076
regulation of purine nucleotide metabolic process GO:1900542 169 0.076
membrane fusion GO:0061025 38 0.075
Human Fly
nuclear transport GO:0051169 139 0.074
cognition GO:0050890 149 0.074
cellular metal ion homeostasis GO:0006875 151 0.074
aromatic compound catabolic process GO:0019439 286 0.073
intracellular protein transport GO:0006886 204 0.072
mapk cascade GO:0000165 281 0.072
Fly
organelle fusion GO:0048284 28 0.071
Human Fly
response to endoplasmic reticulum stress GO:0034976 53 0.071
cellular nitrogen compound catabolic process GO:0044270 280 0.071
cellular macromolecule catabolic process GO:0044265 206 0.071
protein targeting GO:0006605 143 0.070
positive regulation of cellular catabolic process GO:0031331 148 0.070
protein localization to organelle GO:0033365 185 0.070
glycerolipid metabolic process GO:0046486 122 0.069
sequestering of calcium ion GO:0051208 18 0.069
peptidyl serine phosphorylation GO:0018105 74 0.067
action potential GO:0001508 78 0.066
purine nucleoside triphosphate metabolic process GO:0009144 226 0.066
glycosyl compound catabolic process GO:1901658 206 0.064
germ cell development GO:0007281 185 0.064
Fly
fatty acid biosynthetic process GO:0006633 41 0.064
positive regulation of apoptotic signaling pathway GO:2001235 95 0.064
regulation of cellular response to stress GO:0080135 159 0.063
axon guidance GO:0007411 141 0.063
cytosolic calcium ion transport GO:0060401 48 0.063
negative regulation of neuron apoptotic process GO:0043524 92 0.063
phenol containing compound metabolic process GO:0018958 60 0.062
ribonucleoside triphosphate catabolic process GO:0009203 199 0.062
spermatid development GO:0007286 108 0.062
sequestering of metal ion GO:0051238 19 0.061
blood circulation GO:0008015 195 0.059
heart process GO:0003015 94 0.059
metal ion homeostasis GO:0055065 189 0.059
Fly
positive regulation of protein kinase activity GO:0045860 144 0.058
purine nucleotide catabolic process GO:0006195 211 0.058
circadian rhythm GO:0007623 114 0.058
establishment of protein localization to membrane GO:0090150 54 0.058
cellular response to starvation GO:0009267 57 0.058
regulation of establishment of protein localization GO:0070201 181 0.058
regulation of organelle organization GO:0033043 289 0.057
Human Fly
regulation of high voltage gated calcium channel activity GO:1901841 2 0.057
multicellular organism growth GO:0035264 161 0.057
response to organic cyclic compound GO:0014070 198 0.056
glycerolipid biosynthetic process GO:0045017 50 0.056
reactive oxygen species metabolic process GO:0072593 84 0.056
Human
purine ribonucleoside metabolic process GO:0046128 241 0.056
nitrogen compound transport GO:0071705 271 0.056
positive regulation of high voltage gated calcium channel activity GO:1901843 1 0.056
neurotransmitter transport GO:0006836 76 0.055
neuron apoptotic process GO:0051402 142 0.055
carboxylic acid biosynthetic process GO:0046394 86 0.055
positive regulation of hydrolase activity GO:0051345 148 0.055
wnt signaling pathway GO:0016055 188 0.054
regulation of cell motility GO:2000145 236 0.054
Worm
regulation of cardiac muscle contraction GO:0055117 21 0.054
sensory organ morphogenesis GO:0090596 242 0.053
organonitrogen compound biosynthetic process GO:1901566 192 0.053
glial cell differentiation GO:0010001 131 0.053
regulation of cellular amino acid metabolic process GO:0006521 5 0.052
regulation of cytoplasmic transport GO:1903649 112 0.050
regulation of system process GO:0044057 200 0.050
glycosyl compound metabolic process GO:1901657 246 0.050
regulation of intracellular transport GO:0032386 159 0.050
positive regulation of ion transport GO:0043270 65 0.050
purine containing compound catabolic process GO:0072523 213 0.049
homeostasis of number of cells GO:0048872 210 0.048
cardiac muscle cell contraction GO:0086003 7 0.048
purine ribonucleoside catabolic process GO:0046130 205 0.048
canonical wnt signaling pathway GO:0060070 130 0.047
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.047
purine ribonucleotide metabolic process GO:0009150 290 0.047
cellular chemical homeostasis GO:0055082 215 0.047
multi multicellular organism process GO:0044706 109 0.046
purine ribonucleotide catabolic process GO:0009154 208 0.046
glycerophospholipid metabolic process GO:0006650 71 0.046
regulation of neuron death GO:1901214 134 0.045
synaptic vesicle transport GO:0048489 57 0.045
olfactory learning GO:0008355 2 0.045
heart contraction GO:0060047 93 0.045
fat cell differentiation GO:0045444 160 0.045
negative regulation of cellular component organization GO:0051129 194 0.044
Human Worm Fly
muscle cell differentiation GO:0042692 261 0.044
inflammatory response GO:0006954 244 0.044
amino acid transport GO:0006865 61 0.044
organ growth GO:0035265 117 0.044
fatty acid metabolic process GO:0006631 121 0.043
positive regulation of cell death GO:0010942 224 0.043
protein localization to membrane GO:0072657 108 0.043
regulation of hormone secretion GO:0046883 88 0.043
Human
cellular calcium ion homeostasis GO:0006874 119 0.043
synaptic vesicle recycling GO:0036465 19 0.043
meiotic cell cycle process GO:1903046 77 0.043
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.042
phospholipid metabolic process GO:0006644 87 0.042
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.041
response to decreased oxygen levels GO:0036293 59 0.041
development of primary sexual characteristics GO:0045137 143 0.041
positive regulation of growth GO:0045927 104 0.041
organonitrogen compound catabolic process GO:1901565 264 0.041
regulation of cellular component size GO:0032535 121 0.041
peptidyl serine modification GO:0018209 83 0.040
bronchiole morphogenesis GO:0060436 1 0.040
regulation of cellular ketone metabolic process GO:0010565 66 0.040
acetylcholine transport GO:0015870 2 0.040
purine nucleoside triphosphate catabolic process GO:0009146 203 0.040
microtubule based process GO:0007017 236 0.040
carbohydrate derivative catabolic process GO:1901136 231 0.039
establishment of synaptic vesicle localization GO:0097480 57 0.039
positive regulation of secretion by cell GO:1903532 114 0.039
nucleoside triphosphate metabolic process GO:0009141 230 0.039
positive regulation of fat cell proliferation GO:0070346 1 0.038
rhythmic process GO:0048511 174 0.038
adult walking behavior GO:0007628 41 0.038
organic acid biosynthetic process GO:0016053 86 0.038
organophosphate biosynthetic process GO:0090407 122 0.038
regulation of protein kinase activity GO:0045859 232 0.038
nuclear import GO:0051170 95 0.038
hair cycle GO:0042633 90 0.038
carbohydrate metabolic process GO:0005975 230 0.038
Human
regulation of intracellular protein transport GO:0033157 82 0.038
asymmetric neuroblast division GO:0055059 1 0.038
protein oligomerization GO:0051259 67 0.038
white fat cell proliferation GO:0070343 2 0.037
regulation of ion homeostasis GO:2000021 64 0.037
camera type eye development GO:0043010 266 0.037
regulation of kinase activity GO:0043549 249 0.037
Human
nucleoside monophosphate metabolic process GO:0009123 85 0.037
monocarboxylic acid metabolic process GO:0032787 191 0.037
regulation of homeostatic process GO:0032844 182 0.037
positive regulation of protein phosphorylation GO:0001934 242 0.036
response to amino acid GO:0043200 37 0.036
response to nutrient levels GO:0031667 109 0.036
plasma membrane organization GO:0007009 90 0.036
endocytosis GO:0006897 168 0.036
Worm
smooth muscle contraction GO:0006939 44 0.036
negative regulation of homeostatic process GO:0032845 71 0.036
meiotic nuclear division GO:0007126 115 0.036
positive regulation of organelle organization GO:0010638 128 0.036
Human Fly
binding of sperm to zona pellucida GO:0007339 34 0.036
peptide hormone secretion GO:0030072 109 0.036
Human
mitotic cell cycle process GO:1903047 159 0.035
regulation of saliva secretion GO:0046877 2 0.035
peptide secretion GO:0002790 114 0.035
Human
organelle fission GO:0048285 170 0.035
Fly
protein polymerization GO:0051258 57 0.035
positive regulation of ion transmembrane transport GO:0034767 24 0.035
positive regulation of calcium ion transmembrane transporter activity GO:1901021 8 0.035
response to hypoxia GO:0001666 58 0.035
ribonucleoside catabolic process GO:0042454 206 0.035
male sex differentiation GO:0046661 109 0.035
cellular amino acid metabolic process GO:0006520 103 0.034
negative regulation of phosphorus metabolic process GO:0010563 184 0.034
Human Fly
regulation of sodium ion transport GO:0002028 29 0.034
negative regulation of cell proliferation GO:0008285 296 0.034
vesicle localization GO:0051648 86 0.034
sa node cell action potential GO:0086015 4 0.034
muscle contraction GO:0006936 101 0.034
positive regulation of white fat cell proliferation GO:0070352 1 0.033
regulation of actin filament based process GO:0032970 99 0.033
Human
response to insulin GO:0032868 100 0.033
sensory perception of sound GO:0007605 97 0.033
organic hydroxy compound transport GO:0015850 93 0.033
skeletal system development GO:0001501 356 0.033
maintenance of location GO:0051235 89 0.033
actin filament based movement GO:0030048 23 0.032
ribonucleoside metabolic process GO:0009119 245 0.032
female genitalia morphogenesis GO:0048807 3 0.032
protein import GO:0017038 101 0.032
lung proximal distal axis specification GO:0061115 1 0.032
mesenchymal cell differentiation involved in lung development GO:0060915 2 0.032
synapse organization GO:0050808 125 0.031
small molecule biosynthetic process GO:0044283 132 0.031
cellular homeostasis GO:0019725 240 0.031
Fly
calcium ion transport GO:0006816 159 0.031
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.031
regulation of cell cycle GO:0051726 281 0.031
regulation of cell cycle process GO:0010564 160 0.031
small gtpase mediated signal transduction GO:0007264 97 0.030
regulation of blood pressure GO:0008217 93 0.030
peptide transport GO:0015833 133 0.030
Human
regulation of transporter activity GO:0032409 57 0.030
positive regulation of ion transmembrane transporter activity GO:0032414 15 0.029
negative regulation of organelle organization GO:0010639 90 0.029
Human Fly
bone remodeling GO:0046849 53 0.029
calcium ion transport into cytosol GO:0060402 48 0.029
asymmetric stem cell division GO:0098722 3 0.029
response to superoxide GO:0000303 16 0.029
epidermis development GO:0008544 187 0.029
mitochondrial membrane organization GO:0007006 26 0.029
atp catabolic process GO:0006200 55 0.029
ribonucleoside triphosphate metabolic process GO:0009199 220 0.029
regulation of muscle system process GO:0090257 80 0.028
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.028
interspecies interaction between organisms GO:0044419 83 0.028
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.028
receptor mediated endocytosis GO:0006898 51 0.028
response to starvation GO:0042594 65 0.028
regulation of calcium ion transmembrane transporter activity GO:1901019 20 0.028
response to osmotic stress GO:0006970 21 0.027
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.027
cellular response to hormone stimulus GO:0032870 150 0.027
digestive tract development GO:0048565 190 0.027
response to oxygen radical GO:0000305 16 0.027
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.027
positive regulation of activin receptor signaling pathway GO:0032927 3 0.027
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.027
regulation of action potential GO:0098900 4 0.027
regulation of multi organism process GO:0043900 111 0.027
cerebellum development GO:0021549 77 0.027
multi organism behavior GO:0051705 62 0.026
ensheathment of neurons GO:0007272 76 0.026
protein localization to plasma membrane GO:0072659 57 0.026
monovalent inorganic cation homeostasis GO:0055067 33 0.026
release of sequestered calcium ion into cytosol GO:0051209 42 0.026
microtubule cytoskeleton organization GO:0000226 157 0.026
modification dependent protein catabolic process GO:0019941 133 0.026
regulation of calcium ion transmembrane transport GO:1903169 20 0.026
membrane depolarization GO:0051899 64 0.026
regulation of nucleotide catabolic process GO:0030811 122 0.026
regulation of cellular component biogenesis GO:0044087 181 0.026
Human
cellular response to dna damage stimulus GO:0006974 207 0.026
meiotic cell cycle GO:0051321 122 0.026
regulation of cysteine type endopeptidase activity GO:2000116 65 0.026
mammary gland bud formation GO:0060615 2 0.025
leukocyte proliferation GO:0070661 172 0.025
second messenger mediated signaling GO:0019932 73 0.025
ribonucleoside monophosphate metabolic process GO:0009161 80 0.025
positive regulation of cellular amine metabolic process GO:0033240 5 0.025
regulation of proteolysis GO:0030162 164 0.025
response to oxygen levels GO:0070482 62 0.025
lung pattern specification process GO:0060432 1 0.025
regulation of peptidyl serine phosphorylation GO:0033135 39 0.025
single organism nuclear import GO:1902593 95 0.025
protein processing GO:0016485 163 0.025
single fertilization GO:0007338 82 0.025
establishment or maintenance of neuroblast polarity GO:0045196 1 0.025
regulation of neurotransmitter levels GO:0001505 87 0.024
development of primary male sexual characteristics GO:0046546 88 0.024
negative regulation of cytoskeleton organization GO:0051494 36 0.024
Human
response to hydrogen peroxide GO:0042542 32 0.024
negative regulation of neuron death GO:1901215 98 0.024
mitochondrial fusion GO:0008053 9 0.024
Human Fly
signal transduction in absence of ligand GO:0038034 55 0.024
camp metabolic process GO:0046058 40 0.024
divalent inorganic cation homeostasis GO:0072507 138 0.024
Fly
ribonucleotide catabolic process GO:0009261 208 0.024
guanosine containing compound catabolic process GO:1901069 144 0.024
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902176 4 0.024
Human
regulation of cation channel activity GO:2001257 22 0.024
calcium ion homeostasis GO:0055074 127 0.023
cellular amide metabolic process GO:0043603 58 0.023
cellular response to peptide hormone stimulus GO:0071375 92 0.023
regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 33 0.023
gliogenesis GO:0042063 141 0.023
t cell proliferation GO:0042098 120 0.023
submandibular salivary gland formation GO:0060661 1 0.023
axonogenesis GO:0007409 274 0.023
regulation of nucleotide metabolic process GO:0006140 169 0.023
protein localization to nucleus GO:0034504 121 0.022
molting cycle GO:0042303 90 0.022
regulation of inward rectifier potassium channel activity GO:1901979 1 0.022
positive regulation of cell cycle GO:0045787 92 0.022
cell type specific apoptotic process GO:0097285 268 0.022
positive regulation of apoptotic process GO:0043065 217 0.022
posttranscriptional regulation of gene expression GO:0010608 155 0.022
regulation of anatomical structure size GO:0090066 178 0.022
substantia nigra development GO:0021762 2 0.022
compound eye development GO:0048749 1 0.022
protein autophosphorylation GO:0046777 61 0.022
cellular response to organic cyclic compound GO:0071407 87 0.022
cellular response to cadmium ion GO:0071276 3 0.022
positive regulation of calcium ion transport GO:0051928 27 0.022
ventricular cardiac muscle cell action potential GO:0086005 4 0.022
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.022
protein modification by small protein conjugation or removal GO:0070647 207 0.021
t cell activation GO:0042110 289 0.021
response to purine containing compound GO:0014074 28 0.021
purine nucleoside catabolic process GO:0006152 205 0.021
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.021
embryonic genitalia morphogenesis GO:0030538 4 0.021
actin filament polymerization GO:0030041 44 0.021
multicellular organismal response to stress GO:0033555 62 0.021
regulation of nucleoside metabolic process GO:0009118 130 0.021
cellular response to insulin stimulus GO:0032869 78 0.021
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.021
peptide metabolic process GO:0006518 46 0.021
positive regulation of intracellular transport GO:0032388 70 0.021
organelle localization GO:0051640 179 0.021
leukocyte chemotaxis GO:0030595 69 0.021
semicircular canal fusion GO:0060879 1 0.020
lipid biosynthetic process GO:0008610 179 0.020
dicarboxylic acid transport GO:0006835 29 0.020
response to peptide hormone GO:0043434 127 0.020
positive regulation of transmembrane transport GO:0034764 29 0.020
oxidation reduction process GO:0055114 342 0.020
cytosolic calcium ion homeostasis GO:0051480 70 0.020
catecholamine transport GO:0051937 21 0.020
regulation of calcium ion transport GO:0051924 69 0.020
dephosphorylation GO:0016311 129 0.020
positive regulation of wnt signaling pathway GO:0030177 45 0.020
regulation of protein transport GO:0051223 163 0.020
rho protein signal transduction GO:0007266 32 0.020
rna processing GO:0006396 105 0.020
ossification GO:0001503 216 0.020
amino acid import into cell GO:1902837 4 0.020
regulation of purine nucleotide catabolic process GO:0033121 122 0.020
regulation of neurological system process GO:0031644 22 0.020
regulation of bone remodeling GO:0046850 28 0.019
cellular ion homeostasis GO:0006873 165 0.019
developmental cell growth GO:0048588 84 0.019
amino acid uptake involved in synaptic transmission GO:0051933 3 0.019
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.019
positive regulation of sodium ion transport GO:0010765 13 0.019
mating GO:0007618 27 0.019
male gonad development GO:0008584 88 0.019
regulation of cellular response to oxidative stress GO:1900407 19 0.019
cellular response to nutrient levels GO:0031669 64 0.019
cell cell adhesion GO:0098609 41 0.018
regulation of circadian sleep wake cycle GO:0042749 3 0.018
positive regulation of transporter activity GO:0032411 17 0.018
female gamete generation GO:0007292 74 0.018
Fly
l glutamate uptake involved in synaptic transmission GO:0051935 3 0.018
multi organism reproductive behavior GO:0044705 29 0.018
positive regulation of cell motility GO:2000147 116 0.018
nucleoside triphosphate catabolic process GO:0009143 205 0.018
negative regulation of secretion by cell GO:1903531 54 0.018
Human
negative regulation of protein complex disassembly GO:0043242 22 0.018
regulation of peptidase activity GO:0052547 96 0.018
fertilization GO:0009566 127 0.018
chemotaxis GO:0006935 247 0.017
carbohydrate biosynthetic process GO:0016051 74 0.017
intrinsic apoptotic signaling pathway GO:0097193 132 0.017
cell growth GO:0016049 130 0.017
necrotic cell death GO:0070265 30 0.017
response to pain GO:0048265 26 0.017
axon ensheathment GO:0008366 76 0.017
regulation of tumor necrosis factor ligand superfamily member 11 production GO:2000307 1 0.017
carbohydrate homeostasis GO:0033500 128 0.017
monocarboxylic acid biosynthetic process GO:0072330 61 0.017
neuron death GO:0070997 154 0.017
positive regulation of fatty acid biosynthetic process GO:0045723 3 0.017
lateral line system development GO:0048925 1 0.017
regulation of mitotic cell cycle GO:0007346 126 0.017
determination of left right symmetry GO:0007368 80 0.017
positive regulation of behavior GO:0048520 40 0.016
gtp metabolic process GO:0046039 144 0.016
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.016
protein complex disassembly GO:0043241 40 0.016
mesenchymal epithelial cell signaling involved in lung development GO:0060496 1 0.016
calcium mediated signaling GO:0019722 46 0.016
regulation of cell projection organization GO:0031344 206 0.016
regulation of protein complex assembly GO:0043254 83 0.016
regulation of neuron differentiation GO:0045664 281 0.016
nucleoside monophosphate catabolic process GO:0009125 59 0.016
regulation of cell activation GO:0050865 289 0.016
positive regulation of phospholipase c activity GO:0010863 2 0.016
somatostatin signaling pathway GO:0038170 2 0.016
connective tissue development GO:0061448 179 0.016
actin mediated cell contraction GO:0070252 15 0.016
negative regulation of intracellular signal transduction GO:1902532 167 0.016
positive regulation of endopeptidase activity GO:0010950 43 0.016
leukocyte homeostasis GO:0001776 79 0.016
catecholamine metabolic process GO:0006584 30 0.016
visual learning GO:0008542 44 0.016
autophagy GO:0006914 45 0.016
Human Fly
cellular protein complex assembly GO:0043623 116 0.016
epithelial cell proliferation GO:0050673 174 0.016
female sex differentiation GO:0046660 84 0.015
cellular response to cytokine stimulus GO:0071345 189 0.015
Human
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 19 0.015
regulation of phospholipase c activity GO:1900274 3 0.015
activation of adenylate cyclase activity GO:0007190 4 0.015
positive regulation of secretion GO:0051047 130 0.015
positive regulation of cellular component biogenesis GO:0044089 94 0.015
positive regulation of potassium ion transport GO:0043268 3 0.015
positive regulation of cation channel activity GO:2001259 8 0.015
metencephalon development GO:0022037 89 0.015

Park2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.149
Human
central nervous system disease DOID:331 0 0.149
Human
nervous system disease DOID:863 0 0.149
Human
disease of metabolism DOID:0014667 0 0.094
neurodegenerative disease DOID:1289 0 0.055
Human
brain disease DOID:936 0 0.022
electroclinical syndrome DOID:0050701 0 0.018
epilepsy syndrome DOID:1826 0 0.018