Mus musculus

0 known processes

Eif2c3

eukaryotic translation initiation factor 2C, 3

(Aliases: C130014L07Rik,Ago3,AW048688)

Eif2c3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
heterocycle catabolic process GO:0046700 280 0.098
Human
spermatogenesis GO:0007283 284 0.067
glycosyl compound metabolic process GO:1901657 246 0.065
cellular nitrogen compound catabolic process GO:0044270 280 0.064
Human
ras protein signal transduction GO:0007265 77 0.059
male gamete generation GO:0048232 285 0.056
nucleoside metabolic process GO:0009116 246 0.055
ribonucleoside metabolic process GO:0009119 245 0.055
cation transport GO:0006812 399 0.055
purine nucleoside metabolic process GO:0042278 241 0.054
nucleobase containing small molecule metabolic process GO:0055086 352 0.054
organic cyclic compound catabolic process GO:1901361 295 0.053
Human
purine ribonucleoside metabolic process GO:0046128 241 0.050
aromatic compound catabolic process GO:0019439 286 0.050
Human
purine nucleotide catabolic process GO:0006195 211 0.049
nucleoside phosphate metabolic process GO:0006753 338 0.049
nucleoside triphosphate metabolic process GO:0009141 230 0.048
purine nucleotide metabolic process GO:0006163 302 0.048
ribonucleoside triphosphate metabolic process GO:0009199 220 0.048
purine nucleoside triphosphate catabolic process GO:0009146 203 0.047
ribonucleoside catabolic process GO:0042454 206 0.047
small gtpase mediated signal transduction GO:0007264 97 0.046
purine nucleoside catabolic process GO:0006152 205 0.044
carbohydrate derivative catabolic process GO:1901136 231 0.043
organophosphate catabolic process GO:0046434 232 0.043
nucleotide metabolic process GO:0009117 332 0.043
purine containing compound catabolic process GO:0072523 213 0.042
ribonucleotide metabolic process GO:0009259 291 0.042
nucleoside triphosphate catabolic process GO:0009143 205 0.039
purine ribonucleotide metabolic process GO:0009150 290 0.039
nucleoside catabolic process GO:0009164 206 0.039
dna metabolic process GO:0006259 303 0.038
purine ribonucleoside catabolic process GO:0046130 205 0.038
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.038
regulation of cellular ketone metabolic process GO:0010565 66 0.037
glycosyl compound catabolic process GO:1901658 206 0.037
ribose phosphate metabolic process GO:0019693 291 0.037
nucleoside phosphate catabolic process GO:1901292 222 0.037
ribonucleotide catabolic process GO:0009261 208 0.036
positive regulation of cellular catabolic process GO:0031331 148 0.036
cation transmembrane transport GO:0098655 266 0.036
cellular amino acid metabolic process GO:0006520 103 0.036
purine containing compound metabolic process GO:0072521 311 0.035
purine nucleoside triphosphate metabolic process GO:0009144 226 0.034
regulation of cellular amino acid metabolic process GO:0006521 5 0.034
regulation of nucleotide metabolic process GO:0006140 169 0.034
regulation of cellular catabolic process GO:0031329 242 0.033
peptidyl amino acid modification GO:0018193 336 0.033
ion transmembrane transport GO:0034220 361 0.033
negative regulation of cellular protein metabolic process GO:0032269 247 0.033
Human
transmembrane transport GO:0055085 412 0.032
regulation of transferase activity GO:0051338 263 0.032
ribonucleoside triphosphate catabolic process GO:0009203 199 0.032
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.032
purine ribonucleotide catabolic process GO:0009154 208 0.032
rho protein signal transduction GO:0007266 32 0.031
synaptic transmission GO:0007268 329 0.031
protein modification by small protein conjugation or removal GO:0070647 207 0.031
organonitrogen compound catabolic process GO:1901565 264 0.030
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.030
regulation of hydrolase activity GO:0051336 246 0.030
organelle localization GO:0051640 179 0.030
guanosine containing compound metabolic process GO:1901068 144 0.030
amine metabolic process GO:0009308 45 0.029
regulation of cellular amine metabolic process GO:0033238 20 0.028
positive regulation of cellular amine metabolic process GO:0033240 5 0.028
gtp catabolic process GO:0006184 143 0.028
membrane organization GO:0061024 245 0.027
guanosine containing compound catabolic process GO:1901069 144 0.027
negative regulation of protein metabolic process GO:0051248 282 0.027
Human
regulation of protein kinase activity GO:0045859 232 0.027
spermatid differentiation GO:0048515 115 0.026
cellular amine metabolic process GO:0044106 44 0.026
endocytosis GO:0006897 168 0.026
nucleotide catabolic process GO:0009166 217 0.026
organic anion transport GO:0015711 137 0.026
chromatin organization GO:0006325 206 0.026
regulation of gtp catabolic process GO:0033124 113 0.026
regulation of vesicle mediated transport GO:0060627 139 0.026
cellular response to dna damage stimulus GO:0006974 207 0.025
regulation of nucleoside metabolic process GO:0009118 130 0.025
cytoplasmic transport GO:0016482 234 0.025
positive regulation of gtpase activity GO:0043547 85 0.025
regulation of cell activation GO:0050865 289 0.025
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.025
positive regulation of protein modification process GO:0031401 299 0.025
immune effector process GO:0002252 321 0.025
germ cell development GO:0007281 185 0.024
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.024
cellular macromolecule catabolic process GO:0044265 206 0.024
Human
inorganic cation transmembrane transport GO:0098662 207 0.024
positive regulation of hydrolase activity GO:0051345 148 0.024
telencephalon development GO:0021537 186 0.024
leukocyte differentiation GO:0002521 342 0.024
regulation of organelle organization GO:0033043 289 0.024
renal system development GO:0072001 225 0.024
anion transport GO:0006820 177 0.024
inorganic ion transmembrane transport GO:0098660 234 0.024
intracellular protein transport GO:0006886 204 0.024
gtp metabolic process GO:0046039 144 0.023
establishment of organelle localization GO:0051656 122 0.023
regionalization GO:0003002 337 0.023
respiratory system development GO:0060541 190 0.023
macromolecule catabolic process GO:0009057 281 0.023
Human
endomembrane system organization GO:0010256 147 0.023
regulation of ras protein signal transduction GO:0046578 114 0.023
spermatid development GO:0007286 108 0.023
cell type specific apoptotic process GO:0097285 268 0.023
cellular ketone metabolic process GO:0042180 84 0.022
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.022
regulation of purine nucleotide metabolic process GO:1900542 169 0.022
nitrogen compound transport GO:0071705 271 0.022
negative regulation of cellular component organization GO:0051129 194 0.022
cytokine production GO:0001816 319 0.022
cellular homeostasis GO:0019725 240 0.022
regulation of cellular component biogenesis GO:0044087 181 0.022
blood vessel morphogenesis GO:0048514 285 0.022
regulation of cytoskeleton organization GO:0051493 122 0.022
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.021
regulation of neuron differentiation GO:0045664 281 0.021
vesicle localization GO:0051648 86 0.021
covalent chromatin modification GO:0016569 163 0.021
regulation of purine nucleotide catabolic process GO:0033121 122 0.021
regulation of ion transport GO:0043269 215 0.021
regulation of apoptotic signaling pathway GO:2001233 197 0.021
positive regulation of ras gtpase activity GO:0032320 65 0.021
response to organonitrogen compound GO:0010243 246 0.021
stem cell development GO:0048864 219 0.020
protein maturation GO:0051604 176 0.020
regulation of cell projection organization GO:0031344 206 0.020
response to acid chemical GO:0001101 111 0.020
negative regulation of synapse assembly GO:0051964 3 0.020
wnt signaling pathway GO:0016055 188 0.020
negative regulation of intracellular signal transduction GO:1902532 167 0.020
cell adhesion GO:0007155 329 0.020
regulation of kinase activity GO:0043549 249 0.020
engulfment of apoptotic cell GO:0043652 3 0.020
methylation GO:0032259 134 0.020
histone modification GO:0016570 159 0.020
organelle assembly GO:0070925 177 0.020
apoptotic signaling pathway GO:0097190 306 0.020
cellular response to organonitrogen compound GO:0071417 145 0.020
epithelial cell development GO:0002064 159 0.020
cellular lipid metabolic process GO:0044255 323 0.019
positive regulation of nervous system development GO:0051962 221 0.019
cellular response to lipid GO:0071396 145 0.019
positive regulation of nucleotide metabolic process GO:0045981 114 0.019
positive regulation of protein phosphorylation GO:0001934 242 0.019
regulation of cell cycle GO:0051726 281 0.019
positive regulation of nucleoside metabolic process GO:0045979 91 0.019
g protein coupled receptor signaling pathway GO:0007186 243 0.019
regulation of ion transmembrane transport GO:0034765 119 0.019
regulation of cell motility GO:2000145 236 0.019
response to radiation GO:0009314 165 0.019
heart morphogenesis GO:0003007 178 0.019
reactive oxygen species metabolic process GO:0072593 84 0.019
muscle cell differentiation GO:0042692 261 0.019
divalent inorganic cation transport GO:0072511 178 0.018
microtubule based process GO:0007017 236 0.018
negative regulation of phosphorus metabolic process GO:0010563 184 0.018
negative regulation of phosphorylation GO:0042326 166 0.018
negative regulation of phosphate metabolic process GO:0045936 184 0.018
embryonic organ morphogenesis GO:0048562 276 0.018
positive regulation of cell development GO:0010720 237 0.018
protein modification by small protein conjugation GO:0032446 187 0.018
posttranscriptional regulation of gene expression GO:0010608 155 0.018
Human
wound healing GO:0042060 157 0.018
regulation of lymphocyte activation GO:0051249 240 0.018
positive regulation of cell death GO:0010942 224 0.018
regulation of wnt signaling pathway GO:0030111 123 0.018
habituation GO:0046959 3 0.018
oxidation reduction process GO:0055114 342 0.018
rhythmic process GO:0048511 174 0.018
circulatory system process GO:0003013 197 0.018
sensory perception GO:0007600 245 0.018
skeletal system development GO:0001501 356 0.018
protein processing GO:0016485 163 0.017
regulation of ras gtpase activity GO:0032318 88 0.017
regulation of neuron death GO:1901214 134 0.017
regulation of neuron projection development GO:0010975 169 0.017
cellular protein complex assembly GO:0043623 116 0.017
homeostasis of number of cells GO:0048872 210 0.017
epithelial tube morphogenesis GO:0060562 303 0.017
skeletal muscle organ development GO:0060538 163 0.017
positive regulation of gtp catabolic process GO:0033126 85 0.017
exocytosis GO:0006887 121 0.017
urogenital system development GO:0001655 261 0.017
compound eye development GO:0048749 1 0.017
regulation of secretion by cell GO:1903530 249 0.017
regulation of nucleotide catabolic process GO:0030811 122 0.017
respiratory tube development GO:0030323 167 0.017
response to growth factor GO:0070848 198 0.017
hematopoietic progenitor cell differentiation GO:0002244 143 0.017
sensory perception of sound GO:0007605 97 0.017
negative regulation of neuron death GO:1901215 98 0.016
regulation of secretion GO:0051046 274 0.016
carboxylic acid transport GO:0046942 100 0.016
neuron death GO:0070997 154 0.016
lung development GO:0030324 164 0.016
gland development GO:0048732 330 0.016
extracellular structure organization GO:0043062 148 0.016
chemotaxis GO:0006935 247 0.016
forebrain development GO:0030900 302 0.016
adaptive immune response GO:0002250 155 0.016
regulation of lymphocyte mediated immunity GO:0002706 84 0.016
establishment of vesicle localization GO:0051650 81 0.016
fertilization GO:0009566 127 0.016
angiogenesis GO:0001525 201 0.016
regulation of reactive oxygen species metabolic process GO:2000377 40 0.016
divalent metal ion transport GO:0070838 172 0.016
actin cytoskeleton organization GO:0030036 220 0.016
regulation of protein localization GO:0032880 231 0.016
multicellular organism growth GO:0035264 161 0.016
camera type eye development GO:0043010 266 0.016
regulation of anatomical structure size GO:0090066 178 0.016
mapk cascade GO:0000165 281 0.015
sensory perception of mechanical stimulus GO:0050954 107 0.015
protein catabolic process GO:0030163 221 0.015
myotube differentiation GO:0014902 105 0.015
regulation of transmembrane transport GO:0034762 128 0.015
nuclear transport GO:0051169 139 0.015
ossification GO:0001503 216 0.015
dna recombination GO:0006310 92 0.015
response to inorganic substance GO:0010035 96 0.015
cell activation involved in immune response GO:0002263 126 0.015
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.015
striated muscle tissue development GO:0014706 293 0.015
muscle system process GO:0003012 141 0.015
mrna metabolic process GO:0016071 84 0.015
Human
microtubule cytoskeleton organization GO:0000226 157 0.015
sensory organ morphogenesis GO:0090596 242 0.015
nucleoside monophosphate metabolic process GO:0009123 85 0.015
positive regulation of nucleotide catabolic process GO:0030813 88 0.015
histone lysine methylation GO:0034968 50 0.015
dna repair GO:0006281 107 0.015
negative regulation of molecular function GO:0044092 258 0.015
t cell activation GO:0042110 289 0.015
response to lipopolysaccharide GO:0032496 128 0.015
lipid transport GO:0006869 98 0.015
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.015
anatomical structure homeostasis GO:0060249 145 0.015
positive regulation of programmed cell death GO:0043068 218 0.015
regulation of cytokine production GO:0001817 266 0.015
protein localization to membrane GO:0072657 108 0.015
peptidyl serine modification GO:0018209 83 0.015
negative regulation of nervous system development GO:0051961 156 0.015
chromatin modification GO:0016568 187 0.015
nucleocytoplasmic transport GO:0006913 139 0.015
synaptic vesicle localization GO:0097479 59 0.014
regulation of cell migration GO:0030334 219 0.014
organic acid transport GO:0015849 101 0.014
macromolecule methylation GO:0043414 120 0.014
sequestering of metal ion GO:0051238 19 0.014
negative regulation of cell development GO:0010721 169 0.014
cellular protein catabolic process GO:0044257 155 0.014
response to molecule of bacterial origin GO:0002237 143 0.014
central nervous system neuron differentiation GO:0021953 162 0.014
negative regulation of cell proliferation GO:0008285 296 0.014
kidney development GO:0001822 213 0.014
muscle tissue development GO:0060537 308 0.014
lymphocyte activation involved in immune response GO:0002285 93 0.014
synapse organization GO:0050808 125 0.014
stem cell differentiation GO:0048863 268 0.014
leukocyte activation involved in immune response GO:0002366 126 0.014
cognition GO:0050890 149 0.014
morphogenesis of a branching structure GO:0001763 203 0.014
mesodermal cell migration GO:0008078 4 0.014
regulation of striated muscle cell differentiation GO:0051153 81 0.014
positive regulation of transferase activity GO:0051347 167 0.014
leukocyte mediated immunity GO:0002443 174 0.014
cell substrate adhesion GO:0031589 130 0.014
developmental growth involved in morphogenesis GO:0060560 138 0.013
protein ubiquitination GO:0016567 171 0.013
cellular component assembly involved in morphogenesis GO:0010927 139 0.013
response to light stimulus GO:0009416 135 0.013
muscle cell development GO:0055001 133 0.013
digestive tract morphogenesis GO:0048546 147 0.013
neuron apoptotic process GO:0051402 142 0.013
regulation of mapk cascade GO:0043408 248 0.013
regulation of adaptive immune response GO:0002819 90 0.013
maintenance of location GO:0051235 89 0.013
response to oxidative stress GO:0006979 123 0.013
activation of meiosis involved in egg activation GO:0060466 2 0.013
cation homeostasis GO:0055080 212 0.013
lymphocyte mediated immunity GO:0002449 139 0.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.013
regulation of endocytosis GO:0030100 69 0.013
response to organic cyclic compound GO:0014070 198 0.013
learning or memory GO:0007611 148 0.013
negative regulation of protein modification process GO:0031400 163 0.013
regulation of translation GO:0006417 71 0.013
Human
protein localization to organelle GO:0033365 185 0.013
histone methylation GO:0016571 71 0.013
organonitrogen compound biosynthetic process GO:1901566 192 0.013
myeloid cell differentiation GO:0030099 233 0.013
regulation of cell adhesion GO:0030155 154 0.013
ral protein signal transduction GO:0032484 2 0.013
actin filament organization GO:0007015 113 0.013
regulation of protein serine threonine kinase activity GO:0071900 157 0.013
blood circulation GO:0008015 195 0.013
metal ion homeostasis GO:0055065 189 0.013
cellular response to hormone stimulus GO:0032870 150 0.013
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.013
glycerophospholipid metabolic process GO:0006650 71 0.013
retrograde transport endosome to golgi GO:0042147 2 0.013
regulation of hormone levels GO:0010817 211 0.013
protein targeting GO:0006605 143 0.012
positive regulation of kinase activity GO:0033674 155 0.012
regulation of ion transmembrane transporter activity GO:0032412 54 0.012
carboxylic acid biosynthetic process GO:0046394 86 0.012
defecation GO:0030421 1 0.012
cellular metal ion homeostasis GO:0006875 151 0.012
fat cell differentiation GO:0045444 160 0.012
regulation of myotube differentiation GO:0010830 62 0.012
leukocyte migration GO:0050900 124 0.012
cellular response to organic cyclic compound GO:0071407 87 0.012
translation GO:0006412 93 0.012
Human
amino acid transport GO:0006865 61 0.012
endodermal cell fate specification GO:0001714 4 0.012
peptidyl serine phosphorylation GO:0018105 74 0.012
carbohydrate derivative biosynthetic process GO:1901137 183 0.012
regulation of rho protein signal transduction GO:0035023 71 0.012
purine nucleoside monophosphate metabolic process GO:0009126 81 0.012
axonogenesis GO:0007409 274 0.012
calcium ion transport GO:0006816 159 0.012
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.012
nuclear division GO:0000280 158 0.012
regulation of membrane potential GO:0042391 192 0.012
tube formation GO:0035148 140 0.012
extracellular matrix organization GO:0030198 147 0.012
plasma membrane organization GO:0007009 90 0.012
cellular response to growth factor stimulus GO:0071363 197 0.012
multi multicellular organism process GO:0044706 109 0.012
male genitalia morphogenesis GO:0048808 4 0.012
epithelial cell proliferation GO:0050673 174 0.012
protein methylation GO:0006479 81 0.011
dorsal ventral axon guidance GO:0033563 3 0.011
lymphocyte proliferation GO:0046651 164 0.011
protein alkylation GO:0008213 81 0.011
organic acid biosynthetic process GO:0016053 86 0.011
circadian regulation of gene expression GO:0032922 48 0.011
sensory system development GO:0048880 3 0.011
appendage development GO:0048736 166 0.011
positive regulation of growth GO:0045927 104 0.011
ameboidal type cell migration GO:0001667 128 0.011
organelle fission GO:0048285 170 0.011
regulation of actin filament based process GO:0032970 99 0.011
positive regulation of apoptotic process GO:0043065 217 0.011
adult behavior GO:0030534 135 0.011
reactive nitrogen species metabolic process GO:2001057 0 0.011
male anatomical structure morphogenesis GO:0090598 4 0.011
stem cell proliferation GO:0072089 117 0.011
Human
canonical wnt signaling pathway GO:0060070 130 0.011
multicellular organismal homeostasis GO:0048871 164 0.011
regulation of proteolysis GO:0030162 164 0.011
regulation of protein catabolic process GO:0042176 108 0.011
lateral inhibition GO:0046331 1 0.011
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.011
mitochondrion organization GO:0007005 134 0.011
synaptic vesicle transport GO:0048489 57 0.011
vacuole organization GO:0007033 38 0.011
mitotic cell cycle process GO:1903047 159 0.011
neurotransmitter transport GO:0006836 76 0.011
lipid biosynthetic process GO:0008610 179 0.011
regulation of metal ion transport GO:0010959 106 0.011
cellular response to molecule of bacterial origin GO:0071219 83 0.011
regulation of ral gtpase activity GO:0032315 4 0.011
gonad development GO:0008406 141 0.011
regulation of system process GO:0044057 200 0.011
organic hydroxy compound metabolic process GO:1901615 203 0.011
rna catabolic process GO:0006401 29 0.011
Human
tissue homeostasis GO:0001894 115 0.011
ubiquitin dependent protein catabolic process GO:0006511 129 0.011
mitotic cell cycle GO:0000278 195 0.011
intrinsic apoptotic signaling pathway GO:0097193 132 0.011
ear development GO:0043583 200 0.011
glycoprotein metabolic process GO:0009100 116 0.011
regulation of cellular response to growth factor stimulus GO:0090287 82 0.011
cellular response to acid chemical GO:0071229 68 0.011
positive regulation of cell activation GO:0050867 158 0.011
cellular chemical homeostasis GO:0055082 215 0.011
regulation of protein complex assembly GO:0043254 83 0.011
sequestering of calcium ion GO:0051208 18 0.011
regulation of synapse structural plasticity GO:0051823 4 0.011
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.011
cytokinetic process GO:0032506 2 0.011
b cell activation GO:0042113 161 0.010
regulation of cellular response to stress GO:0080135 159 0.010
negative regulation of apoptotic signaling pathway GO:2001234 104 0.010
regulation of leukocyte mediated immunity GO:0002703 104 0.010
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.010
regulation of clathrin mediated endocytosis GO:2000369 4 0.010
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.010
negative regulation of cellular amine metabolic process GO:0033239 1 0.010
rna interference GO:0016246 2 0.010
lymphocyte differentiation GO:0030098 242 0.010
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.010
morphogenesis of embryonic epithelium GO:0016331 159 0.010
divalent inorganic cation homeostasis GO:0072507 138 0.010
developmental maturation GO:0021700 193 0.010
rap protein signal transduction GO:0032486 3 0.010
regulation of transporter activity GO:0032409 57 0.010
cell growth GO:0016049 130 0.010
pallium development GO:0021543 120 0.010
phagocytosis GO:0006909 66 0.010
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.010
calcium ion homeostasis GO:0055074 127 0.010
skeletal system morphogenesis GO:0048705 203 0.010
neuron projection guidance GO:0097485 141 0.010

Eif2c3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.030
cancer DOID:162 0 0.026
organ system cancer DOID:0050686 0 0.026
disease of anatomical entity DOID:7 0 0.026
nervous system disease DOID:863 0 0.026
immune system disease DOID:2914 0 0.018
central nervous system disease DOID:331 0 0.017
disease of metabolism DOID:0014667 0 0.015
inherited metabolic disorder DOID:655 0 0.015
hematopoietic system disease DOID:74 0 0.015
musculoskeletal system disease DOID:17 0 0.014
connective tissue disease DOID:65 0 0.014
immune system cancer DOID:0060083 0 0.013
hematologic cancer DOID:2531 0 0.013
bone disease DOID:0080001 0 0.013
neurodegenerative disease DOID:1289 0 0.012