Mus musculus

263 known processes

Paxip1

PAX interacting (with transcription-activation domain) protein 1

(Aliases: PTIP,D5Ertd149e)

Paxip1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
chromatin organization GO:0006325 206 0.539
histone lysine methylation GO:0034968 50 0.419
organelle fission GO:0048285 170 0.371
covalent chromatin modification GO:0016569 163 0.325
mitotic cell cycle GO:0000278 195 0.320
histone modification GO:0016570 159 0.297
dna metabolic process GO:0006259 303 0.246
chromatin modification GO:0016568 187 0.215
nuclear division GO:0000280 158 0.201
macromolecule methylation GO:0043414 120 0.191
mitotic cell cycle process GO:1903047 159 0.185
regulation of cell cycle GO:0051726 281 0.118
regulation of mitotic cell cycle phase transition GO:1901990 73 0.117
internal protein amino acid acetylation GO:0006475 42 0.101
peptidyl amino acid modification GO:0018193 336 0.099
peptidyl lysine modification GO:0018205 77 0.095
histone methylation GO:0016571 71 0.090
meiosis i GO:0007127 60 0.088
negative regulation of cell cycle phase transition GO:1901988 48 0.086
microtubule based process GO:0007017 236 0.083
meiotic nuclear division GO:0007126 115 0.079
somatic diversification of immune receptors GO:0002200 53 0.075
protein alkylation GO:0008213 81 0.075
nitrogen compound transport GO:0071705 271 0.073
histone h3 acetylation GO:0043966 14 0.071
histone acetylation GO:0016573 41 0.070
immune effector process GO:0002252 321 0.068
germ cell development GO:0007281 185 0.067
mitotic nuclear division GO:0007067 48 0.066
methylation GO:0032259 134 0.064
negative regulation of histone h3 k9 methylation GO:0051573 4 0.063
cell division GO:0051301 120 0.062
protein acylation GO:0043543 64 0.061
lymphocyte mediated immunity GO:0002449 139 0.058
skeletal system development GO:0001501 356 0.058
negative regulation of mesenchymal cell proliferation GO:0072201 3 0.057
regulation of histone methylation GO:0031060 30 0.057
immunoglobulin production GO:0002377 73 0.057
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.054
dna recombination GO:0006310 92 0.053
amine metabolic process GO:0009308 45 0.050
protein methylation GO:0006479 81 0.049
regulation of lymphocyte activation GO:0051249 240 0.048
dna repair GO:0006281 107 0.047
meiotic cell cycle GO:0051321 122 0.047
negative regulation of mesenchymal cell proliferation involved in lung development GO:2000791 2 0.047
positive regulation of hydrolase activity GO:0051345 148 0.046
camera type eye development GO:0043010 266 0.046
gland development GO:0048732 330 0.046
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 3 0.045
retina development in camera type eye GO:0060041 119 0.044
cellular protein complex assembly GO:0043623 116 0.043
regulation of cell cycle process GO:0010564 160 0.043
macromolecule catabolic process GO:0009057 281 0.042
regulation of histone h3 k9 methylation GO:0051570 8 0.042
leukocyte differentiation GO:0002521 342 0.041
regulation of chromosome organization GO:0033044 83 0.040
regulation of mitotic cell cycle GO:0007346 126 0.040
cellular ketone metabolic process GO:0042180 84 0.039
negative regulation of mitotic cell cycle GO:0045930 58 0.038
microtubule cytoskeleton organization GO:0000226 157 0.038
b cell activation GO:0042113 161 0.038
ear development GO:0043583 200 0.038
positive regulation of cellular amine metabolic process GO:0033240 5 0.037
regulation of cell activation GO:0050865 289 0.037
aromatic compound catabolic process GO:0019439 286 0.037
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.037
positive regulation of nucleotide catabolic process GO:0030813 88 0.036
immunoglobulin mediated immune response GO:0016064 69 0.036
histone h3 k4 methylation GO:0051568 23 0.036
negative regulation of cellular component organization GO:0051129 194 0.036
developmental maturation GO:0021700 193 0.036
cell fate commitment GO:0045165 210 0.035
histone h3 k9 methylation GO:0051567 17 0.034
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.034
leukocyte activation involved in immune response GO:0002366 126 0.033
negative regulation of cell cycle GO:0045786 123 0.033
cellular response to dna damage stimulus GO:0006974 207 0.033
blastocyst growth GO:0001832 23 0.033
skin development GO:0043588 220 0.033
mrna metabolic process GO:0016071 84 0.033
protein modification by small protein conjugation or removal GO:0070647 207 0.032
regulation of cellular amino acid metabolic process GO:0006521 5 0.032
lymphocyte differentiation GO:0030098 242 0.032
glycosyl compound metabolic process GO:1901657 246 0.032
spermatogenesis GO:0007283 284 0.031
dna templated transcriptional preinitiation complex assembly GO:0070897 4 0.031
negative regulation of cell cycle process GO:0010948 69 0.030
intracellular protein transport GO:0006886 204 0.030
rna processing GO:0006396 105 0.030
adaptive immune response GO:0002250 155 0.030
production of molecular mediator of immune response GO:0002440 103 0.029
regulation of organelle organization GO:0033043 289 0.029
urogenital system development GO:0001655 261 0.029
regulation of cell cycle phase transition GO:1901987 77 0.028
regulation of cellular ketone metabolic process GO:0010565 66 0.028
positive regulation of apoptotic process GO:0043065 217 0.028
response to acid chemical GO:0001101 111 0.028
double strand break repair GO:0006302 48 0.028
negative regulation of cellular protein metabolic process GO:0032269 247 0.028
positive regulation of intracellular estrogen receptor signaling pathway GO:0033148 4 0.028
cellular response to growth factor stimulus GO:0071363 197 0.028
meiotic cell cycle process GO:1903046 77 0.027
stem cell differentiation GO:0048863 268 0.027
positive regulation of lymphocyte activation GO:0051251 140 0.027
gonad development GO:0008406 141 0.027
organonitrogen compound catabolic process GO:1901565 264 0.027
stem cell development GO:0048864 219 0.027
regulation of lymphocyte mediated immunity GO:0002706 84 0.026
positive regulation of cell activation GO:0050867 158 0.026
heterocycle catabolic process GO:0046700 280 0.026
neural tube development GO:0021915 160 0.026
epidermis development GO:0008544 187 0.026
cell cycle checkpoint GO:0000075 47 0.025
cytoplasmic transport GO:0016482 234 0.025
intracellular mrna localization GO:0008298 4 0.025
homeostasis of number of cells GO:0048872 210 0.025
development of primary sexual characteristics GO:0045137 143 0.025
male meiosis i GO:0007141 16 0.025
cation transport GO:0006812 399 0.025
somatic recombination of immunoglobulin gene segments GO:0016447 42 0.024
cellular amine metabolic process GO:0044106 44 0.024
dna endoreduplication GO:0042023 4 0.024
chemotaxis GO:0006935 247 0.024
lipid biosynthetic process GO:0008610 179 0.024
regulation of asymmetric cell division GO:0009786 4 0.024
negative regulation of organelle organization GO:0010639 90 0.024
cellular macromolecule catabolic process GO:0044265 206 0.024
regulation of establishment of protein localization GO:0070201 181 0.023
response to radiation GO:0009314 165 0.023
Human
negative regulation of protein metabolic process GO:0051248 282 0.023
regulation of cellular amine metabolic process GO:0033238 20 0.023
purine nucleoside triphosphate metabolic process GO:0009144 226 0.023
organic hydroxy compound metabolic process GO:1901615 203 0.023
positive regulation of cell death GO:0010942 224 0.023
female gamete generation GO:0007292 74 0.023
epithelial tube formation GO:0072175 130 0.023
dna replication GO:0006260 52 0.022
nucleobase containing small molecule metabolic process GO:0055086 352 0.022
regionalization GO:0003002 337 0.022
Fly
immunoglobulin production involved in immunoglobulin mediated immune response GO:0002381 43 0.022
endocytosis GO:0006897 168 0.022
protein modification by small protein conjugation GO:0032446 187 0.022
t cell activation GO:0042110 289 0.022
cellular amino acid metabolic process GO:0006520 103 0.022
regulation of nuclear division GO:0051783 56 0.022
calcium ion transport GO:0006816 159 0.022
mrna splicing via spliceosome GO:0000398 43 0.022
metanephric dct cell differentiation GO:0072240 3 0.022
response to organic cyclic compound GO:0014070 198 0.021
platelet derived growth factor receptor alpha signaling pathway GO:0035790 3 0.021
ras protein signal transduction GO:0007265 77 0.021
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.021
organic cyclic compound catabolic process GO:1901361 295 0.021
digestive system development GO:0055123 200 0.021
regulation of mesenchymal cell proliferation involved in lung development GO:2000790 2 0.021
protein maturation GO:0051604 176 0.020
positive regulation of b cell activation GO:0050871 49 0.020
transmission of nerve impulse GO:0019226 76 0.020
internal peptidyl lysine acetylation GO:0018393 42 0.020
male gamete generation GO:0048232 285 0.020
sensory organ morphogenesis GO:0090596 242 0.020
peptidyl lysine acetylation GO:0018394 45 0.020
digestive tract development GO:0048565 190 0.019
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.019
locomotory behavior GO:0007626 195 0.019
nucleus organization GO:0006997 45 0.019
proteasomal protein catabolic process GO:0010498 98 0.019
blastocyst development GO:0001824 80 0.019
cell adhesion GO:0007155 329 0.019
nucleoside metabolic process GO:0009116 246 0.019
oxidation reduction process GO:0055114 342 0.019
posttranscriptional regulation of gene expression GO:0010608 155 0.019
cellular nitrogen compound catabolic process GO:0044270 280 0.019
regulation of membrane potential GO:0042391 192 0.019
tube closure GO:0060606 91 0.019
cell growth GO:0016049 130 0.019
body morphogenesis GO:0010171 45 0.019
action potential GO:0001508 78 0.018
protein targeting GO:0006605 143 0.018
monoubiquitinated histone deubiquitination GO:0035521 1 0.018
cellular modified amino acid metabolic process GO:0006575 63 0.018
b cell mediated immunity GO:0019724 71 0.018
fertilization GO:0009566 127 0.018
embryonic organ morphogenesis GO:0048562 276 0.018
gastrulation GO:0007369 116 0.018
gene silencing GO:0016458 38 0.018
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 51 0.018
positive regulation of immune effector process GO:0002699 107 0.018
regulation of protein complex assembly GO:0043254 83 0.018
protein ubiquitination GO:0016567 171 0.018
response to oxidative stress GO:0006979 123 0.018
adult locomotory behavior GO:0008344 91 0.018
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.018
somatic cell dna recombination GO:0016444 51 0.018
double strand break repair via nonhomologous end joining GO:0006303 10 0.018
regulation of cell division GO:0051302 76 0.018
male meiosis GO:0007140 37 0.017
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.017
positive regulation of programmed cell death GO:0043068 218 0.017
carbohydrate derivative catabolic process GO:1901136 231 0.017
divalent inorganic cation transport GO:0072511 178 0.017
membrane organization GO:0061024 245 0.017
response to growth factor GO:0070848 198 0.017
negative regulation of histone methylation GO:0031061 10 0.017
modification dependent protein catabolic process GO:0019941 133 0.017
neural tube closure GO:0001843 90 0.017
organelle assembly GO:0070925 177 0.017
positive regulation of hormone metabolic process GO:0032352 3 0.017
nuclear import GO:0051170 95 0.017
establishment of protein localization to organelle GO:0072594 118 0.017
ion transmembrane transport GO:0034220 361 0.017
regulation of cytoskeleton organization GO:0051493 122 0.017
positive regulation of histone h3 k4 methylation GO:0051571 5 0.017
nuclear transport GO:0051169 139 0.017
cellular response to acid chemical GO:0071229 68 0.017
negative regulation of cell proliferation GO:0008285 296 0.016
rho protein signal transduction GO:0007266 32 0.016
regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis GO:0072039 4 0.016
leukocyte mediated immunity GO:0002443 174 0.016
protein polymerization GO:0051258 57 0.016
cellular response to organic cyclic compound GO:0071407 87 0.016
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.016
nucleocytoplasmic transport GO:0006913 139 0.016
embryonic epithelial tube formation GO:0001838 130 0.016
recombinational repair GO:0000725 21 0.016
regulation of protein transport GO:0051223 163 0.016
forebrain development GO:0030900 302 0.016
lateral inhibition GO:0046331 1 0.016
metanephric distal convoluted tubule development GO:0072221 5 0.016
adult behavior GO:0030534 135 0.016
stem cell proliferation GO:0072089 117 0.016
regulation of secretion GO:0051046 274 0.016
stem cell maintenance GO:0019827 130 0.016
nucleotide excision repair GO:0006289 13 0.016
organophosphate catabolic process GO:0046434 232 0.016
primary neural tube formation GO:0014020 95 0.016
purine ribonucleoside metabolic process GO:0046128 241 0.016
nucleoside phosphate metabolic process GO:0006753 338 0.016
positive regulation of nucleoside metabolic process GO:0045979 91 0.015
lymphocyte activation involved in immune response GO:0002285 93 0.015
purine containing compound metabolic process GO:0072521 311 0.015
histone deubiquitination GO:0016578 2 0.015
wnt signaling pathway GO:0016055 188 0.015
purine nucleoside metabolic process GO:0042278 241 0.015
regulation of b cell activation GO:0050864 81 0.015
protein processing GO:0016485 163 0.015
regulation of intracellular transport GO:0032386 159 0.015
somatic diversification of immunoglobulins GO:0016445 43 0.015
intracellular receptor signaling pathway GO:0030522 74 0.015
neural tube formation GO:0001841 108 0.015
inner ear receptor cell development GO:0060119 39 0.015
glycosyl compound catabolic process GO:1901658 206 0.015
cell activation involved in immune response GO:0002263 126 0.015
establishment or maintenance of cell polarity GO:0007163 86 0.015
b cell activation involved in immune response GO:0002312 50 0.015
mechanoreceptor differentiation GO:0042490 67 0.015
divalent metal ion transport GO:0070838 172 0.015
endomembrane system organization GO:0010256 147 0.015
response to extracellular stimulus GO:0009991 127 0.015
regulation of chromatin modification GO:1903308 57 0.015
positive regulation of protein modification process GO:0031401 299 0.015
purine nucleotide catabolic process GO:0006195 211 0.015
spermatid development GO:0007286 108 0.014
inner ear receptor cell differentiation GO:0060113 61 0.014
microtubule organizing center organization GO:0031023 28 0.014
regulation of protein localization GO:0032880 231 0.014
regulation of platelet derived growth factor receptor alpha signaling pathway GO:2000583 2 0.014
protein import GO:0017038 101 0.014
protein localization to nucleus GO:0034504 121 0.014
bone development GO:0060348 120 0.014
dct cell differentiation GO:0072069 3 0.014
protein modification by small protein removal GO:0070646 21 0.014
protein catabolic process GO:0030163 221 0.014
oocyte anterior posterior axis specification GO:0007314 2 0.014
somatic recombination of immunoglobulin genes involved in immune response GO:0002204 36 0.014
multicellular organismal signaling GO:0035637 91 0.014
nucleoside triphosphate metabolic process GO:0009141 230 0.014
nucleoside triphosphate catabolic process GO:0009143 205 0.014
maintenance of location GO:0051235 89 0.014
cell type specific apoptotic process GO:0097285 268 0.014
rna interference GO:0016246 2 0.014
b cell differentiation GO:0030183 78 0.014
tube formation GO:0035148 140 0.014
cytokine production GO:0001816 319 0.014
ribonucleoside metabolic process GO:0009119 245 0.014
respiratory system development GO:0060541 190 0.013
response to estrogen GO:0043627 24 0.013
kidney epithelium development GO:0072073 121 0.013
hindbrain development GO:0030902 128 0.013
positive regulation of cellular component biogenesis GO:0044089 94 0.013
regulation of t cell activation GO:0050863 170 0.013
reactive oxygen species metabolic process GO:0072593 84 0.013
protein import into nucleus GO:0006606 95 0.013
ribonucleoside triphosphate metabolic process GO:0009199 220 0.013
purine nucleotide metabolic process GO:0006163 302 0.013
response to light stimulus GO:0009416 135 0.013
compound eye development GO:0048749 1 0.013
regulation of hormone levels GO:0010817 211 0.013
cellular homeostasis GO:0019725 240 0.013
respiratory tube development GO:0030323 167 0.013
single organism nuclear import GO:1902593 95 0.013
positive regulation of nucleotide metabolic process GO:0045981 114 0.013
tubulin deacetylation GO:0090042 4 0.013
positive regulation of organelle organization GO:0010638 128 0.013
purine containing compound catabolic process GO:0072523 213 0.013
dna dependent dna replication maintenance of fidelity GO:0045005 3 0.013
inner cell mass cell proliferation GO:0001833 15 0.013
regulation of hydrolase activity GO:0051336 246 0.013
segmentation GO:0035282 93 0.013
purine ribonucleoside catabolic process GO:0046130 205 0.013
translation GO:0006412 93 0.013
isotype switching GO:0045190 36 0.013
kidney development GO:0001822 213 0.013
ribose phosphate metabolic process GO:0019693 291 0.013
small molecule biosynthetic process GO:0044283 132 0.013
oogenesis GO:0048477 56 0.013
negative regulation of mesenchymal cell apoptotic process involved in metanephros development GO:1900212 4 0.013
embryonic axis specification GO:0000578 30 0.013
mitotic cell cycle checkpoint GO:0007093 31 0.013
lipoprotein metabolic process GO:0042157 43 0.012
pharynx development GO:0060465 1 0.012
mrna processing GO:0006397 63 0.012
nuclear export GO:0051168 34 0.012
rna splicing GO:0008380 54 0.012
double strand break repair via homologous recombination GO:0000724 21 0.012
regulation of chromatin organization GO:1902275 57 0.012
asymmetric stem cell division GO:0098722 3 0.012
cell cycle g1 s phase transition GO:0044843 57 0.012
ribonucleotide metabolic process GO:0009259 291 0.012
posttranscriptional gene silencing GO:0016441 10 0.012
transmembrane transport GO:0055085 412 0.012
positive regulation of metanephric glomerulus development GO:0072300 4 0.012
negative regulation of cell development GO:0010721 169 0.012
negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis GO:0072040 4 0.012
nucleotide catabolic process GO:0009166 217 0.012
telencephalon development GO:0021537 186 0.012
response to organonitrogen compound GO:0010243 246 0.012
cell maturation GO:0048469 127 0.012
cellular response to lipid GO:0071396 145 0.012
carboxylic acid biosynthetic process GO:0046394 86 0.012
response to retinoic acid GO:0032526 56 0.012
attachment of spindle microtubules to kinetochore GO:0008608 4 0.012
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.012
carbohydrate metabolic process GO:0005975 230 0.012
response to molecule of bacterial origin GO:0002237 143 0.012
regulation of wnt signaling pathway GO:0030111 123 0.012
regulation of cellular component biogenesis GO:0044087 181 0.012
epithelial cell development GO:0002064 159 0.012
pancreas development GO:0031016 57 0.012
small gtpase mediated signal transduction GO:0007264 97 0.011
neuronal action potential GO:0019228 54 0.011
regulation of cell cycle g2 m phase transition GO:1902749 10 0.011
skeletal system morphogenesis GO:0048705 203 0.011
development of primary male sexual characteristics GO:0046546 88 0.011
regulation of response to wounding GO:1903034 189 0.011
female gonad development GO:0008585 71 0.011
detection of chemical stimulus involved in sensory perception of smell GO:0050911 4 0.011
cofactor metabolic process GO:0051186 80 0.011
positive regulation of gtpase activity GO:0043547 85 0.011
purine nucleoside catabolic process GO:0006152 205 0.011
regulation of cytokine production GO:0001817 266 0.011
response to peptide GO:1901652 136 0.011
regulation of dna recombination GO:0000018 34 0.011
monoubiquitinated protein deubiquitination GO:0035520 2 0.011
dephosphorylation GO:0016311 129 0.011
cellular response to organonitrogen compound GO:0071417 145 0.011
t cell differentiation GO:0030217 174 0.011
multicellular organismal homeostasis GO:0048871 164 0.011
development of primary female sexual characteristics GO:0046545 73 0.011
purine nucleoside triphosphate catabolic process GO:0009146 203 0.011
regulation of leukocyte proliferation GO:0070663 121 0.011
peptidyl lysine methylation GO:0018022 29 0.011
multi multicellular organism process GO:0044706 109 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.011
divalent inorganic cation homeostasis GO:0072507 138 0.011
gliogenesis GO:0042063 141 0.011
histone h3 k9 dimethylation GO:0036123 4 0.011
regulation of circadian rhythm GO:0042752 58 0.011
response to nutrient levels GO:0031667 109 0.011
regulation of secretion by cell GO:1903530 249 0.011
maternal determination of anterior posterior axis embryo GO:0008358 2 0.011
lymphocyte apoptotic process GO:0070227 54 0.010
vestibulocochlear nerve morphogenesis GO:0021648 4 0.010
regulation of purine nucleotide metabolic process GO:1900542 169 0.010
negative regulation of growth GO:0045926 99 0.010
cellular response to hormone stimulus GO:0032870 150 0.010
regulation of cellular response to stress GO:0080135 159 0.010
hair cell differentiation GO:0035315 40 0.010
apoptotic process involved in development GO:1902742 28 0.010
lung alveolus development GO:0048286 45 0.010
engulfment of apoptotic cell GO:0043652 3 0.010
regulation of steroid metabolic process GO:0019218 39 0.010
cellular response to cytokine stimulus GO:0071345 189 0.010
leukocyte migration GO:0050900 124 0.010
carbohydrate homeostasis GO:0033500 128 0.010
organelle localization GO:0051640 179 0.010
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.010
regulation of anatomical structure size GO:0090066 178 0.010
single fertilization GO:0007338 82 0.010
establishment or maintenance of neuroblast polarity GO:0045196 1 0.010
positive regulation of b cell mediated immunity GO:0002714 26 0.010
negative regulation of protein processing GO:0010955 79 0.010

Paxip1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.037
disease of cellular proliferation DOID:14566 0 0.037
disease of anatomical entity DOID:7 0 0.022
Human
nervous system disease DOID:863 0 0.022
Human
organ system cancer DOID:0050686 0 0.019
retinal disease DOID:5679 0 0.016
retinal degeneration DOID:8466 0 0.016
sensory system disease DOID:0050155 0 0.016
eye and adnexa disease DOID:1492 0 0.016
eye disease DOID:5614 0 0.016
immune system cancer DOID:0060083 0 0.014
hematologic cancer DOID:2531 0 0.014