Mus musculus

21 known processes

Tjp1

tight junction protein 1

(Aliases: ZO1)

Tjp1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
neuronal action potential GO:0019228 54 0.997
cell cell junction organization GO:0045216 72 0.994
apical junction assembly GO:0043297 15 0.994
action potential GO:0001508 78 0.988
ensheathment of neurons GO:0007272 76 0.985
multicellular organismal signaling GO:0035637 91 0.985
transmission of nerve impulse GO:0019226 76 0.978
cell junction organization GO:0034330 77 0.962
regulation of membrane potential GO:0042391 192 0.940
sa node cell to atrial cardiac muscle cell signalling GO:0086018 4 0.940
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 40 0.937
regulation of membrane depolarization during action potential GO:0098902 1 0.919
cell adhesion GO:0007155 329 0.915
calcium independent cell cell adhesion via plasma membrane cell adhesion molecules GO:0016338 4 0.907
cell communication by electrical coupling involved in cardiac conduction GO:0086064 2 0.903
milk ejection GO:0060156 1 0.900
cell cell junction assembly GO:0007043 27 0.859
regulation of renin secretion into blood stream GO:1900133 4 0.854
regulation of ventricular cardiac muscle cell membrane depolarization GO:0060373 2 0.835
neuronal action potential propagation GO:0019227 8 0.835
axon ensheathment GO:0008366 76 0.834
regulation of membrane depolarization GO:0003254 11 0.797
av node cell to bundle of his cell communication GO:0086067 2 0.791
ventricular cardiac muscle cell action potential GO:0086005 4 0.770
cell cell adhesion GO:0098609 41 0.769
cell junction assembly GO:0034329 52 0.748
actin filament based movement GO:0030048 23 0.748
cardiac muscle cell contraction GO:0086003 7 0.743
cell communication by chemical coupling GO:0010643 2 0.713
foramen ovale closure GO:0035922 1 0.627
macromolecule catabolic process GO:0009057 281 0.624
sa node cell action potential GO:0086015 4 0.617
spermatogenesis GO:0007283 284 0.591
organophosphate catabolic process GO:0046434 232 0.582
protein catabolic process GO:0030163 221 0.574
regulation of actin filament based process GO:0032970 99 0.550
regulation of body fluid levels GO:0050878 162 0.543
protein localization to cell junction GO:1902414 3 0.503
tight junction assembly GO:0070830 9 0.490
purine nucleoside metabolic process GO:0042278 241 0.471
muscle contraction GO:0006936 101 0.445
regulation of behavioral fear response GO:2000822 2 0.443
sensory perception of mechanical stimulus GO:0050954 107 0.441
atrial ventricular junction remodeling GO:0003294 2 0.428
muscle system process GO:0003012 141 0.422
myelination GO:0042552 74 0.397
actin mediated cell contraction GO:0070252 15 0.387
cell communication involved in cardiac conduction GO:0086065 9 0.380
small gtpase mediated signal transduction GO:0007264 97 0.356
regulation of striated muscle contraction GO:0006942 25 0.331
ras protein signal transduction GO:0007265 77 0.323
regulation of cell activation GO:0050865 289 0.318
cardiac muscle cell action potential GO:0086001 11 0.315
regulation of membrane depolarization during cardiac muscle cell action potential GO:1900825 1 0.304
membrane organization GO:0061024 245 0.302
regulation of homeostatic process GO:0032844 182 0.298
cardiac conduction GO:0061337 17 0.296
circulatory system process GO:0003013 197 0.294
Rat
cellular component assembly involved in morphogenesis GO:0010927 139 0.287
ion transmembrane transport GO:0034220 361 0.277
actin filament organization GO:0007015 113 0.271
striated muscle contraction GO:0006941 45 0.268
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.263
actin filament bundle assembly GO:0051017 40 0.263
regulation of ion transmembrane transport GO:0034765 119 0.262
membrane depolarization during action potential GO:0086010 5 0.260
regulation of cardiac muscle contraction GO:0055117 21 0.251
positive regulation of neuron projection development GO:0010976 79 0.250
single organismal cell cell adhesion GO:0016337 131 0.248
neuron migration GO:0001764 122 0.241
actin cytoskeleton organization GO:0030036 220 0.240
satellite cell activation involved in skeletal muscle regeneration GO:0014901 3 0.231
modification dependent macromolecule catabolic process GO:0043632 133 0.229
establishment of organelle localization GO:0051656 122 0.224
regulation of cardiac muscle cell contraction GO:0086004 11 0.218
regulation of ion transport GO:0043269 215 0.218
regulation of vesicle mediated transport GO:0060627 139 0.215
adult behavior GO:0030534 135 0.211
regulation of heart contraction GO:0008016 77 0.211
cardiac muscle contraction GO:0060048 32 0.208
modification dependent protein catabolic process GO:0019941 133 0.205
olfactory learning GO:0008355 2 0.204
skin development GO:0043588 220 0.199
actin polymerization or depolymerization GO:0008154 54 0.196
regulation of atrial cardiac muscle cell membrane depolarization GO:0060371 5 0.192
locomotory behavior GO:0007626 195 0.190
labyrinthine layer development GO:0060711 49 0.185
intrinsic apoptotic signaling pathway in response to osmotic stress GO:0008627 2 0.181
regulation of blood circulation GO:1903522 93 0.181
sa node cell to atrial cardiac muscle cell communication GO:0086070 5 0.180
adult locomotory behavior GO:0008344 91 0.179
purine nucleotide catabolic process GO:0006195 211 0.177
membrane depolarization GO:0051899 64 0.176
gtp catabolic process GO:0006184 143 0.176
sensory perception GO:0007600 245 0.173
synapse organization GO:0050808 125 0.173
synaptic transmission GO:0007268 329 0.170
regulation of ion homeostasis GO:2000021 64 0.169
actin filament polymerization GO:0030041 44 0.166
purine nucleoside catabolic process GO:0006152 205 0.164
synapse assembly GO:0007416 56 0.163
glycosyl compound catabolic process GO:1901658 206 0.161
sodium ion transport GO:0006814 73 0.161
regulation of heart rate GO:0002027 36 0.160
regulation of transmembrane transport GO:0034762 128 0.157
cytoskeleton dependent intracellular transport GO:0030705 50 0.156
axonogenesis GO:0007409 274 0.154
positive regulation of rho gtpase activity GO:0032321 41 0.154
body morphogenesis GO:0010171 45 0.153
cytosolic calcium ion homeostasis GO:0051480 70 0.152
cellular protein catabolic process GO:0044257 155 0.151
positive regulation of kinase activity GO:0033674 155 0.149
positive regulation of cellular catabolic process GO:0031331 148 0.149
muscle cell development GO:0055001 133 0.148
multicellular organismal water homeostasis GO:0050891 23 0.148
regulation of pinocytosis GO:0048548 1 0.146
multicellular organismal response to stress GO:0033555 62 0.144
positive regulation of gtpase activity GO:0043547 85 0.143
ribonucleoside triphosphate catabolic process GO:0009203 199 0.143
mitotic cell cycle GO:0000278 195 0.141
cellular response to osmotic stress GO:0071470 7 0.141
heart contraction GO:0060047 93 0.140
protein oligomerization GO:0051259 67 0.140
spermatid development GO:0007286 108 0.140
establishment or maintenance of cell polarity GO:0007163 86 0.140
regulation of actin filament length GO:0030832 45 0.139
transmembrane transport GO:0055085 412 0.138
nucleotide catabolic process GO:0009166 217 0.136
organelle localization GO:0051640 179 0.136
regulation of intracellular transport GO:0032386 159 0.135
inflammatory response GO:0006954 244 0.134
cell cell signaling involved in cardiac conduction GO:0086019 6 0.128
regulation of cardiac muscle cell action potential GO:0098901 1 0.128
protein localization to membrane GO:0072657 108 0.127
myosin filament assembly GO:0031034 2 0.126
inorganic ion transmembrane transport GO:0098660 234 0.126
negative regulation of phosphorus metabolic process GO:0010563 184 0.126
neuron projection guidance GO:0097485 141 0.125
regulation of muscle contraction GO:0006937 49 0.123
regulation of actin cytoskeleton organization GO:0032956 84 0.121
endomembrane system organization GO:0010256 147 0.121
regulation of actin filament polymerization GO:0030833 38 0.120
cell recognition GO:0008037 83 0.119
purine ribonucleoside catabolic process GO:0046130 205 0.119
adherens junction organization GO:0034332 28 0.119
actomyosin structure organization GO:0031032 56 0.117
myofibril assembly GO:0030239 34 0.117
male gamete generation GO:0048232 285 0.115
oocyte axis specification GO:0007309 2 0.115
regulation of cellular component biogenesis GO:0044087 181 0.115
regulation of secretion by cell GO:1903530 249 0.114
cardiac muscle cell action potential involved in contraction GO:0086002 6 0.114
endocytosis GO:0006897 168 0.114
positive regulation of gtp catabolic process GO:0033126 85 0.114
cell fate commitment GO:0045165 210 0.112
negative regulation of molecular function GO:0044092 258 0.109
regulation of organelle organization GO:0033043 289 0.109
neuromuscular process GO:0050905 99 0.106
germ cell development GO:0007281 185 0.105
regulation of protein transport GO:0051223 163 0.105
microtubule cytoskeleton organization GO:0000226 157 0.104
oocyte construction GO:0007308 2 0.104
digestive system development GO:0055123 200 0.103
t cell activation GO:0042110 289 0.102
regulation of protein localization GO:0032880 231 0.102
regulation of cell adhesion GO:0030155 154 0.102
protein targeting GO:0006605 143 0.101
positive regulation of protein kinase activity GO:0045860 144 0.101
striated muscle tissue development GO:0014706 293 0.100
detection of light stimulus GO:0009583 25 0.098
guanosine containing compound metabolic process GO:1901068 144 0.096
positive regulation of secretion GO:0051047 130 0.096
regulation of fear response GO:1903365 2 0.096
sensory perception of sound GO:0007605 97 0.096
regulation of receptor activity GO:0010469 41 0.096
water homeostasis GO:0030104 27 0.095
septum primum development GO:0003284 4 0.094
calcium ion homeostasis GO:0055074 127 0.094
response to hypoxia GO:0001666 58 0.094
regulation of secretion GO:0051046 274 0.094
intracellular protein transport GO:0006886 204 0.093
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.093
cellular response to abiotic stimulus GO:0071214 56 0.092
regulation of ras gtpase activity GO:0032318 88 0.092
regulation of protein kinase activity GO:0045859 232 0.092
microtubule based movement GO:0007018 84 0.092
regulation of satellite cell activation involved in skeletal muscle regeneration GO:0014717 3 0.091
cell type specific apoptotic process GO:0097285 268 0.091
glycosyl compound metabolic process GO:1901657 246 0.090
sarcomere organization GO:0045214 24 0.089
regulation of tube size GO:0035150 57 0.089
muscle cell differentiation GO:0042692 261 0.089
rho protein signal transduction GO:0007266 32 0.087
regulation of protein secretion GO:0050708 82 0.087
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.086
regulation of gtp catabolic process GO:0033124 113 0.086
regulation of endocytosis GO:0030100 69 0.085
cell communication by electrical coupling GO:0010644 4 0.085
regulation of cellular ketone metabolic process GO:0010565 66 0.085
actin cytoskeleton reorganization GO:0031532 21 0.085
regulation of actin filament based movement GO:1903115 12 0.084
sequestering of calcium ion GO:0051208 18 0.084
purine nucleoside triphosphate metabolic process GO:0009144 226 0.084
cellular ion homeostasis GO:0006873 165 0.084
cytoplasmic transport GO:0016482 234 0.083
regulation of metal ion transport GO:0010959 106 0.083
nucleoside metabolic process GO:0009116 246 0.082
regulation of cell cycle GO:0051726 281 0.082
detection of abiotic stimulus GO:0009582 60 0.080
regulation of muscle system process GO:0090257 80 0.079
response to peptide hormone GO:0043434 127 0.079
positive regulation of cell projection organization GO:0031346 95 0.079
spongiotrophoblast layer development GO:0060712 15 0.079
regulation of nucleotide catabolic process GO:0030811 122 0.078
axon guidance GO:0007411 141 0.078
protein modification by small protein conjugation or removal GO:0070647 207 0.078
nucleoside monophosphate metabolic process GO:0009123 85 0.078
negative regulation of cell proliferation GO:0008285 296 0.078
myeloid cell homeostasis GO:0002262 114 0.077
cation transmembrane transport GO:0098655 266 0.077
cellular divalent inorganic cation homeostasis GO:0072503 127 0.077
regulation of purine nucleotide catabolic process GO:0033121 122 0.077
ribonucleoside triphosphate metabolic process GO:0009199 220 0.077
cell adhesion mediated by integrin GO:0033627 18 0.076
cation transport GO:0006812 399 0.076
reflex GO:0060004 22 0.075
oogenesis GO:0048477 56 0.075
renal system process involved in regulation of blood volume GO:0001977 4 0.074
regulation of neuron differentiation GO:0045664 281 0.074
heart process GO:0003015 94 0.074
organelle assembly GO:0070925 177 0.074
regulation of systemic arterial blood pressure by hormone GO:0001990 25 0.074
vasodilation GO:0042311 28 0.073
regulation of nucleoside metabolic process GO:0009118 130 0.073
positive regulation of ras gtpase activity GO:0032320 65 0.073
spermatid differentiation GO:0048515 115 0.072
sodium ion transmembrane transport GO:0035725 49 0.072
regulation of cellular amino acid metabolic process GO:0006521 5 0.072
regulation of t cell proliferation GO:0042129 92 0.071
cellular nitrogen compound catabolic process GO:0044270 280 0.071
ribonucleoside catabolic process GO:0042454 206 0.071
purine ribonucleotide catabolic process GO:0009154 208 0.071
response to light stimulus GO:0009416 135 0.071
ribose phosphate metabolic process GO:0019693 291 0.070
vascular process in circulatory system GO:0003018 62 0.070
Rat
striated muscle cell development GO:0055002 125 0.070
positive regulation of vasoconstriction GO:0045907 4 0.069
adenine nucleotide transport GO:0051503 2 0.069
membrane depolarization during cardiac muscle cell action potential GO:0086012 5 0.069
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.069
regulation of establishment of protein localization GO:0070201 181 0.069
digestive tract morphogenesis GO:0048546 147 0.068
ribonucleotide catabolic process GO:0009261 208 0.068
dendrite development GO:0016358 115 0.068
vesicle organization GO:0016050 60 0.067
regulation of system process GO:0044057 200 0.066
metal ion homeostasis GO:0055065 189 0.066
adaptive immune response GO:0002250 155 0.066
regulation of apoptotic signaling pathway GO:2001233 197 0.066
positive regulation of nucleotide catabolic process GO:0030813 88 0.066
inorganic cation transmembrane transport GO:0098662 207 0.066
regulation of membrane repolarization GO:0060306 7 0.065
learning GO:0007612 98 0.065
response to oxygen levels GO:0070482 62 0.065
protein localization to plasma membrane GO:0072659 57 0.065
organ growth GO:0035265 117 0.065
regulation of actin nucleation GO:0051125 4 0.064
regulation of mapk cascade GO:0043408 248 0.064
purine ribonucleotide metabolic process GO:0009150 290 0.064
regulation of inositol 1 4 5 trisphosphate sensitive calcium release channel activity GO:0031585 2 0.063
nucleoside phosphate catabolic process GO:1901292 222 0.063
nucleoside catabolic process GO:0009164 206 0.063
regulation of t cell activation GO:0050863 170 0.062
divalent inorganic cation homeostasis GO:0072507 138 0.062
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.062
regulation of cytoskeleton organization GO:0051493 122 0.062
immune effector process GO:0002252 321 0.062
fertilization GO:0009566 127 0.062
detection of visible light GO:0009584 14 0.060
ribonucleotide metabolic process GO:0009259 291 0.060
regulation of hydrolase activity GO:0051336 246 0.060
neuron apoptotic process GO:0051402 142 0.060
response to peptide GO:1901652 136 0.060
embryonic organ morphogenesis GO:0048562 276 0.059
rac protein signal transduction GO:0016601 13 0.059
maintenance of location in cell GO:0051651 24 0.058
regulation of blood pressure GO:0008217 93 0.057
divalent metal ion transport GO:0070838 172 0.057
regeneration GO:0031099 38 0.057
regulation of response to wounding GO:1903034 189 0.056
purine nucleotide metabolic process GO:0006163 302 0.056
meiotic cell cycle GO:0051321 122 0.056
nitrogen compound transport GO:0071705 271 0.056
regulation of systemic arterial blood pressure GO:0003073 61 0.056
organonitrogen compound catabolic process GO:1901565 264 0.055
positive regulation of secretion by cell GO:1903532 114 0.054
leukocyte mediated immunity GO:0002443 174 0.054
negative regulation of intracellular signal transduction GO:1902532 167 0.054
regulation of peptide transport GO:0090087 91 0.054
leukocyte migration GO:0050900 124 0.054
limb morphogenesis GO:0035108 149 0.053
cellular macromolecule catabolic process GO:0044265 206 0.053
t cell proliferation GO:0042098 120 0.053
positive regulation of nucleoside metabolic process GO:0045979 91 0.053
regulation of ion transmembrane transporter activity GO:0032412 54 0.053
positive regulation of actin nucleation GO:0051127 3 0.053
mesodermal cell migration GO:0008078 4 0.053
establishment of protein localization to membrane GO:0090150 54 0.053
nucleoside phosphate metabolic process GO:0006753 338 0.052
purine nucleoside triphosphate catabolic process GO:0009146 203 0.051
regulation of cellular response to stress GO:0080135 159 0.051
positive regulation of cell adhesion GO:0045785 80 0.051
aromatic compound catabolic process GO:0019439 286 0.051
cellular ketone metabolic process GO:0042180 84 0.051
cellular amine metabolic process GO:0044106 44 0.051
positive regulation of apoptotic process GO:0043065 217 0.050
insulin secretion GO:0030073 89 0.050
regulation of cell substrate adhesion GO:0010810 73 0.050
sequestering of metal ion GO:0051238 19 0.050
protein polymerization GO:0051258 57 0.050
maintenance of location GO:0051235 89 0.050
positive regulation of endocytosis GO:0045807 42 0.050
regulation of purine nucleotide metabolic process GO:1900542 169 0.050
peptide transport GO:0015833 133 0.050
pigmentation GO:0043473 71 0.050
embryonic epithelial tube formation GO:0001838 130 0.049
membrane repolarization GO:0086009 7 0.049
regulation of leukocyte proliferation GO:0070663 121 0.049
lymphocyte proliferation GO:0046651 164 0.048
divalent inorganic cation transport GO:0072511 178 0.048
nuclear division GO:0000280 158 0.048
intrinsic apoptotic signaling pathway GO:0097193 132 0.047
muscle tissue development GO:0060537 308 0.047
developmental maturation GO:0021700 193 0.047
regulation of actin polymerization or depolymerization GO:0008064 45 0.047
nucleoside triphosphate catabolic process GO:0009143 205 0.047
neural tube development GO:0021915 160 0.047
ubiquitin dependent protein catabolic process GO:0006511 129 0.047
carbohydrate derivative catabolic process GO:1901136 231 0.047
ribonucleoside metabolic process GO:0009119 245 0.046
response to ph GO:0009268 14 0.046
response to organonitrogen compound GO:0010243 246 0.046
ameboidal type cell migration GO:0001667 128 0.046
integrin mediated signaling pathway GO:0007229 27 0.046
regulation of lymphocyte activation GO:0051249 240 0.045
organelle fission GO:0048285 170 0.045
microtubule based process GO:0007017 236 0.045
glial cell differentiation GO:0010001 131 0.045
guanosine containing compound catabolic process GO:1901069 144 0.045
negative regulation of growth GO:0045926 99 0.044
positive regulation of cellular amine metabolic process GO:0033240 5 0.044
regulation of cytoplasmic transport GO:1903649 112 0.044
cell matrix adhesion GO:0007160 68 0.044
renal response to blood flow involved in circulatory renin angiotensin regulation of systemic arterial blood pressure GO:0001999 6 0.044
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.044
cellular metal ion homeostasis GO:0006875 151 0.044
cation homeostasis GO:0055080 212 0.043
positive regulation of ion transport GO:0043270 65 0.043
regulation of cell migration GO:0030334 219 0.043
lens development in camera type eye GO:0002088 62 0.043
receptor mediated endocytosis GO:0006898 51 0.042
regulation of neuron projection development GO:0010975 169 0.042
positive regulation of hydrolase activity GO:0051345 148 0.042
establishment of skin barrier GO:0061436 14 0.042
mitotic nuclear division GO:0007067 48 0.042
detection of stimulus GO:0051606 84 0.042
cell substrate adhesion GO:0031589 130 0.042
response to radiation GO:0009314 165 0.042
syncytium formation GO:0006949 43 0.041
gland development GO:0048732 330 0.041
myeloid leukocyte activation GO:0002274 83 0.041
regulation of protein catabolic process GO:0042176 108 0.040
immune response activating signal transduction GO:0002757 116 0.040
focal adhesion assembly GO:0048041 19 0.040
skeletal muscle organ development GO:0060538 163 0.040
regulation of glomerular filtration GO:0003093 3 0.039
protein modification by small protein conjugation GO:0032446 187 0.039
organophosphate ester transport GO:0015748 28 0.039
wnt signaling pathway GO:0016055 188 0.039
positive regulation of cell development GO:0010720 237 0.039
regulation of arp2 3 complex mediated actin nucleation GO:0034315 1 0.038
positive regulation of receptor activity GO:2000273 17 0.038
regulation of skeletal muscle tissue regeneration GO:0043416 5 0.038
regulation of ossification GO:0030278 112 0.038
spindle localization GO:0051653 22 0.038
nucleobase containing small molecule metabolic process GO:0055086 352 0.038
anion transport GO:0006820 177 0.037
neuron death GO:0070997 154 0.037
nucleoside monophosphate catabolic process GO:0009125 59 0.037
protein ubiquitination GO:0016567 171 0.036
positive regulation of cell death GO:0010942 224 0.036
cell activation involved in immune response GO:0002263 126 0.036
striated muscle myosin thick filament assembly GO:0071688 1 0.036
positive regulation of map kinase activity GO:0043406 84 0.036
regulation of tissue remodeling GO:0034103 38 0.036
metencephalon development GO:0022037 89 0.036
single organism cell adhesion GO:0098602 156 0.036
calcium ion transport GO:0006816 159 0.036
protein localization to organelle GO:0033365 185 0.036
embryonic placenta development GO:0001892 98 0.035
nucleoside triphosphate metabolic process GO:0009141 230 0.035
cellular calcium ion homeostasis GO:0006874 119 0.035
heterocycle catabolic process GO:0046700 280 0.035
retina development in camera type eye GO:0060041 119 0.035
anatomical structure homeostasis GO:0060249 145 0.035
regulation of calcium ion transport into cytosol GO:0010522 31 0.035
regulation of bone remodeling GO:0046850 28 0.034
camera type eye development GO:0043010 266 0.034
positive regulation of nucleotide metabolic process GO:0045981 114 0.034
regulation of transferase activity GO:0051338 263 0.034
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.034
homeostasis of number of cells GO:0048872 210 0.034
multi multicellular organism process GO:0044706 109 0.034
regionalization GO:0003002 337 0.034
regulation of heart rate by cardiac conduction GO:0086091 6 0.033
regulation of cell junction assembly GO:1901888 14 0.033
sensory perception of light stimulus GO:0050953 54 0.033
cellular lipid metabolic process GO:0044255 323 0.033
single organism nuclear import GO:1902593 95 0.033
stem cell differentiation GO:0048863 268 0.032
positive regulation of protein catabolic process GO:0045732 60 0.032
epithelial tube morphogenesis GO:0060562 303 0.032
positive regulation of vasodilation GO:0045909 3 0.032
placenta development GO:0001890 140 0.032
membrane fusion GO:0061025 38 0.032
second messenger mediated signaling GO:0019932 73 0.032
epithelial cell development GO:0002064 159 0.032
cellular homeostasis GO:0019725 240 0.032
Rat
positive regulation of protein transport GO:0051222 93 0.032
golgi localization GO:0051645 4 0.032
leukocyte activation involved in immune response GO:0002366 126 0.031
ear development GO:0043583 200 0.031
positive regulation of defense response GO:0031349 124 0.031
i kappab kinase nf kappab signaling GO:0007249 85 0.031
cellular response to insulin stimulus GO:0032869 78 0.031
compound eye development GO:0048749 1 0.031
negative regulation of homeostatic process GO:0032845 71 0.031
mesoderm development GO:0007498 100 0.031
biomineral tissue development GO:0031214 64 0.031
lymphocyte differentiation GO:0030098 242 0.031
regulation of lymphocyte proliferation GO:0050670 117 0.031
regulation of engulfment of apoptotic cell GO:1901074 2 0.031
regulation of hormone secretion GO:0046883 88 0.031
telencephalon development GO:0021537 186 0.031
positive regulation of cell motility GO:2000147 116 0.031
establishment or maintenance of apical basal cell polarity GO:0035088 21 0.031
nucleobase containing compound transport GO:0015931 27 0.030
atp metabolic process GO:0046034 75 0.030
regulation of cellular catabolic process GO:0031329 242 0.030
regulation of neuron apoptotic process GO:0043523 122 0.030
peptidyl amino acid modification GO:0018193 336 0.030
cellularization GO:0007349 1 0.030
neutrophil migration GO:1990266 37 0.030
negative regulation of protein metabolic process GO:0051248 282 0.030
protein secretion GO:0009306 111 0.030
visual perception GO:0007601 52 0.030
mitotic cytokinesis GO:0000281 4 0.030
associative learning GO:0008306 61 0.030
blood circulation GO:0008015 195 0.030
Rat
negative regulation of neuron death GO:1901215 98 0.029
digestive tract development GO:0048565 190 0.029
detection of external stimulus GO:0009581 61 0.029
positive regulation of glomerular filtration GO:0003104 1 0.029
regulation of cell shape GO:0008360 39 0.029
regulation of protein serine threonine kinase activity GO:0071900 157 0.029
leukocyte proliferation GO:0070661 172 0.029
stem cell development GO:0048864 219 0.029
leukocyte differentiation GO:0002521 342 0.029
negative regulation of apoptotic signaling pathway GO:2001234 104 0.029
positive regulation of ion transmembrane transport GO:0034767 24 0.029
cellular component maintenance GO:0043954 11 0.029
myelination in peripheral nervous system GO:0022011 19 0.029
hormone secretion GO:0046879 128 0.029
organic cyclic compound catabolic process GO:1901361 295 0.028
cytosolic calcium ion transport GO:0060401 48 0.028
oocyte differentiation GO:0009994 35 0.028
skeletal system development GO:0001501 356 0.028

Tjp1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
nephritis DOID:10952 0 0.601
glomerulonephritis DOID:2921 0 0.601
focal segmental glomerulosclerosis DOID:1312 0 0.601
kidney disease DOID:557 0 0.601
disease of anatomical entity DOID:7 0 0.601
urinary system disease DOID:18 0 0.601
glomerulosclerosis DOID:0050851 0 0.601
central nervous system disease DOID:331 0 0.154
nervous system disease DOID:863 0 0.154
bone development disease DOID:0080006 0 0.106
bone disease DOID:0080001 0 0.106
musculoskeletal system disease DOID:17 0 0.106
connective tissue disease DOID:65 0 0.106
cerebral degeneration DOID:1443 0 0.086
brain disease DOID:936 0 0.086
cardiovascular system disease DOID:1287 0 0.061
disease of cellular proliferation DOID:14566 0 0.040
gastrointestinal system disease DOID:77 0 0.034