Mus musculus

68 known processes

Nek2

NIMA (never in mitosis gene a)-related expressed kinase 2

(Aliases: AA617254,C77054)

Nek2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
spindle assembly involved in mitosis GO:0090307 4 0.954
organelle assembly GO:0070925 177 0.939
microtubule cytoskeleton organization involved in mitosis GO:1902850 4 0.857
microtubule based process GO:0007017 236 0.844
dna metabolic process GO:0006259 303 0.827
spindle assembly GO:0051225 13 0.818
regulation of spindle organization GO:0090224 2 0.795
microtubule cytoskeleton organization GO:0000226 157 0.747
microtubule organizing center organization GO:0031023 28 0.740
Human
centrosome cycle GO:0007098 23 0.709
Human
meiotic cell cycle process GO:1903046 77 0.709
mitotic cell cycle GO:0000278 195 0.699
mitotic cell cycle process GO:1903047 159 0.654
nuclear division GO:0000280 158 0.624
meiotic nuclear division GO:0007126 115 0.564
chromosome segregation GO:0007059 48 0.534
female meiosis chromosome segregation GO:0016321 1 0.522
cytokinesis GO:0000910 17 0.503
regulation of cell cycle GO:0051726 281 0.494
Fly
regulation of cell cycle process GO:0010564 160 0.469
Fly
meiotic chromosome segregation GO:0045132 19 0.466
centrosome separation GO:0051299 4 0.452
Human
organelle fission GO:0048285 170 0.448
mitotic cytokinesis GO:0000281 4 0.445
establishment of organelle localization GO:0051656 122 0.443
cleavage furrow formation GO:0036089 2 0.422
purine nucleoside catabolic process GO:0006152 205 0.385
cytokinetic process GO:0032506 2 0.363
negative regulation of cell cycle phase transition GO:1901988 48 0.361
positive regulation of chromosome segregation GO:0051984 4 0.352
cellular protein catabolic process GO:0044257 155 0.338
modification dependent protein catabolic process GO:0019941 133 0.333
cellular macromolecule catabolic process GO:0044265 206 0.330
protein catabolic process GO:0030163 221 0.324
dna replication GO:0006260 52 0.322
positive regulation of cell cycle GO:0045787 92 0.321
meiosis i GO:0007127 60 0.318
cellular response to dna damage stimulus GO:0006974 207 0.312
ubiquitin dependent protein catabolic process GO:0006511 129 0.302
regulation of mitotic cell cycle phase transition GO:1901990 73 0.300
regulation of mitotic cell cycle GO:0007346 126 0.298
Fly
double strand break repair GO:0006302 48 0.291
male meiosis GO:0007140 37 0.289
spindle organization GO:0007051 28 0.281
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.275
cell division GO:0051301 120 0.272
Fly
spindle midzone assembly GO:0051255 1 0.271
regulation of cell division GO:0051302 76 0.265
Fly
ribonucleoside catabolic process GO:0042454 206 0.261
regulation of organelle organization GO:0033043 289 0.260
Human Fly
negative regulation of cell cycle GO:0045786 123 0.258
cell cycle checkpoint GO:0000075 47 0.254
mitotic sister chromatid segregation GO:0000070 14 0.251
regulation of cytoskeleton organization GO:0051493 122 0.249
Human
metaphase plate congression GO:0051310 2 0.244
nucleoside phosphate catabolic process GO:1901292 222 0.239
meiotic cell cycle GO:0051321 122 0.237
mitotic spindle organization GO:0007052 10 0.235
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.224
purine nucleotide metabolic process GO:0006163 302 0.213
meiotic cytokinesis GO:0033206 5 0.206
microtubule based movement GO:0007018 84 0.206
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.200
germ cell development GO:0007281 185 0.200
chromatin organization GO:0006325 206 0.198
male gamete generation GO:0048232 285 0.195
maintenance of location GO:0051235 89 0.194
Human
negative regulation of mitotic cell cycle GO:0045930 58 0.192
metaphase anaphase transition of mitotic cell cycle GO:0007091 9 0.186
ribonucleoside metabolic process GO:0009119 245 0.178
regulation of cellular catabolic process GO:0031329 242 0.178
dna repair GO:0006281 107 0.175
dna recombination GO:0006310 92 0.174
mitotic nuclear division GO:0007067 48 0.166
astral microtubule organization GO:0030953 3 0.158
organelle localization GO:0051640 179 0.158
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 16 0.155
macromolecule catabolic process GO:0009057 281 0.150
centrosome organization GO:0051297 26 0.149
Human
cell cycle comprising mitosis without cytokinesis GO:0033301 1 0.148
attachment of spindle microtubules to kinetochore GO:0008608 4 0.146
Human
purine nucleotide catabolic process GO:0006195 211 0.146
centrosome duplication GO:0051298 16 0.142
regulation of proteasomal protein catabolic process GO:0061136 46 0.142
regulation of chromosome segregation GO:0051983 21 0.139
Human
dna endoreduplication GO:0042023 4 0.139
meiosis ii GO:0007135 7 0.137
regulation of protein kinase activity GO:0045859 232 0.135
regulation of mitotic sister chromatid segregation GO:0033047 12 0.135
nucleoside triphosphate metabolic process GO:0009141 230 0.134
chromosome separation GO:0051304 14 0.134
spindle assembly involved in meiosis GO:0090306 4 0.127
glycosyl compound catabolic process GO:1901658 206 0.127
negative regulation of organelle organization GO:0010639 90 0.125
Human
negative regulation of microtubule polymerization or depolymerization GO:0031111 15 0.123
sister chromatid segregation GO:0000819 20 0.122
dephosphorylation GO:0016311 129 0.121
spindle localization GO:0051653 22 0.121
establishment of meiotic spindle orientation GO:0051296 1 0.120
purine containing compound catabolic process GO:0072523 213 0.120
ribose phosphate metabolic process GO:0019693 291 0.118
spindle assembly involved in female meiosis GO:0007056 3 0.118
mitotic chromosome condensation GO:0007076 1 0.116
negative regulation of cellular component organization GO:0051129 194 0.115
Human
regulation of protein catabolic process GO:0042176 108 0.115
regulation of cytokinesis GO:0032465 5 0.114
positive regulation of mitotic cell cycle GO:0045931 41 0.108
cellular protein complex assembly GO:0043623 116 0.107
regulation of mitotic spindle organization GO:0060236 2 0.106
microtubule depolymerization GO:0007019 15 0.105
organonitrogen compound catabolic process GO:1901565 264 0.102
regulation of microtubule polymerization or depolymerization GO:0031110 20 0.101
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 15 0.101
chromatin modification GO:0016568 187 0.100
positive regulation of mitotic sister chromatid separation GO:1901970 2 0.100
regulation of cell cycle phase transition GO:1901987 77 0.098
nucleoside catabolic process GO:0009164 206 0.098
covalent chromatin modification GO:0016569 163 0.097
apoptotic signaling pathway GO:0097190 306 0.096
modification dependent macromolecule catabolic process GO:0043632 133 0.095
response to radiation GO:0009314 165 0.095
female meiotic division GO:0007143 21 0.095
purine ribonucleotide catabolic process GO:0009154 208 0.094
regulation of mitosis GO:0007088 29 0.094
Fly
mitotic centrosome separation GO:0007100 4 0.093
organic cyclic compound catabolic process GO:1901361 295 0.091
regulation of kinase activity GO:0043549 249 0.090
posttranscriptional regulation of gene expression GO:0010608 155 0.090
Fly
dna conformation change GO:0071103 37 0.090
proteasomal protein catabolic process GO:0010498 98 0.090
purine nucleoside triphosphate catabolic process GO:0009146 203 0.087
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.087
positive regulation of cell cycle process GO:0090068 61 0.086
cellular response to radiation GO:0071478 28 0.086
ribonucleoside triphosphate metabolic process GO:0009199 220 0.085
protein depolymerization GO:0051261 34 0.084
purine nucleoside triphosphate metabolic process GO:0009144 226 0.084
histone modification GO:0016570 159 0.083
centriole assembly GO:0098534 6 0.083
regulation of metaphase anaphase transition of cell cycle GO:1902099 9 0.082
purine nucleoside metabolic process GO:0042278 241 0.082
positive regulation of mitotic metaphase anaphase transition GO:0045842 2 0.081
purine ribonucleotide metabolic process GO:0009150 290 0.079
nucleoside triphosphate catabolic process GO:0009143 205 0.079
heterocycle catabolic process GO:0046700 280 0.078
spermatogenesis GO:0007283 284 0.078
positive regulation of cellular protein catabolic process GO:1903364 34 0.078
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.078
regulation of microtubule based process GO:0032886 52 0.078
Human
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.077
positive regulation of protein modification process GO:0031401 299 0.076
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.076
regulation of protein maturation GO:1903317 96 0.076
peptidyl serine modification GO:0018209 83 0.074
cellularization GO:0007349 1 0.074
microtubule nucleation GO:0007020 2 0.072
fertilization GO:0009566 127 0.072
spindle checkpoint GO:0031577 12 0.071
histone serine phosphorylation GO:0035404 5 0.070
single fertilization GO:0007338 82 0.070
mitotic spindle assembly checkpoint GO:0007094 7 0.069
mitotic sister chromatid separation GO:0051306 9 0.068
ribonucleoside triphosphate catabolic process GO:0009203 199 0.068
cellular amino acid metabolic process GO:0006520 103 0.066
aromatic compound catabolic process GO:0019439 286 0.066
oocyte maturation GO:0001556 18 0.066
regulation of chromosome organization GO:0033044 83 0.065
regulation of nucleoside metabolic process GO:0009118 130 0.065
glycosyl compound metabolic process GO:1901657 246 0.063
purine nucleoside monophosphate catabolic process GO:0009128 58 0.063
synapsis GO:0007129 34 0.063
establishment of spindle localization GO:0051293 19 0.062
cellular protein complex disassembly GO:0043624 36 0.061
rho protein signal transduction GO:0007266 32 0.061
ribonucleotide metabolic process GO:0009259 291 0.061
regulation of protein serine threonine kinase activity GO:0071900 157 0.060
negative regulation of protein metabolic process GO:0051248 282 0.059
positive regulation of cellular catabolic process GO:0031331 148 0.058
endomembrane system organization GO:0010256 147 0.057
gonad development GO:0008406 141 0.056
purine containing compound metabolic process GO:0072521 311 0.056
purine ribonucleoside metabolic process GO:0046128 241 0.056
protein modification by small protein conjugation GO:0032446 187 0.055
organophosphate catabolic process GO:0046434 232 0.055
negative regulation of cytoskeleton organization GO:0051494 36 0.055
Human
establishment of spindle orientation GO:0051294 15 0.055
chromosome movement towards spindle pole GO:0051305 3 0.054
reciprocal meiotic recombination GO:0007131 16 0.054
nucleoside metabolic process GO:0009116 246 0.054
positive regulation of protein kinase activity GO:0045860 144 0.053
purine ribonucleoside catabolic process GO:0046130 205 0.053
negative regulation of cellular protein metabolic process GO:0032269 247 0.053
ribonucleoside monophosphate metabolic process GO:0009161 80 0.052
cellular nitrogen compound catabolic process GO:0044270 280 0.051
atp catabolic process GO:0006200 55 0.050
carbohydrate derivative catabolic process GO:1901136 231 0.050
small gtpase mediated signal transduction GO:0007264 97 0.050
nucleotide metabolic process GO:0009117 332 0.049
actin cytoskeleton organization GO:0030036 220 0.049
endocytosis GO:0006897 168 0.049
negative regulation of cellular protein catabolic process GO:1903363 22 0.049
sister chromatid cohesion GO:0007062 12 0.048
regulation of cellular response to stress GO:0080135 159 0.048
regulation of proteolysis GO:0030162 164 0.048
synaptonemal complex assembly GO:0007130 13 0.047
development of primary sexual characteristics GO:0045137 143 0.047
double strand break repair via homologous recombination GO:0000724 21 0.047
histone phosphorylation GO:0016572 9 0.047
dna damage response signal transduction resulting in transcription GO:0042772 2 0.047
negative regulation of mitosis GO:0045839 10 0.046
regulation of nuclear cell cycle dna replication GO:0033262 2 0.046
positive regulation of cell cycle phase transition GO:1901989 17 0.046
cilium morphogenesis GO:0060271 102 0.045
regulation of cellular component size GO:0032535 121 0.045
translesion synthesis GO:0019985 1 0.045
regulation of binding GO:0051098 111 0.044
oocyte differentiation GO:0009994 35 0.044
regulation of microtubule cytoskeleton organization GO:0070507 37 0.044
Human
cellular response to abiotic stimulus GO:0071214 56 0.044
response to ionizing radiation GO:0010212 42 0.044
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.044
negative regulation of cell size GO:0045792 3 0.044
male meiosis i GO:0007141 16 0.044
ribonucleotide catabolic process GO:0009261 208 0.043
purine nucleoside monophosphate metabolic process GO:0009126 81 0.043
regulation of cellular protein catabolic process GO:1903362 61 0.043
negative regulation of microtubule depolymerization GO:0007026 13 0.043
negative regulation of sister chromatid segregation GO:0033046 7 0.042
regulation of protein processing GO:0070613 96 0.042
cell cycle g1 s phase transition GO:0044843 57 0.042
intrinsic apoptotic signaling pathway GO:0097193 132 0.041
peptidyl serine phosphorylation GO:0018105 74 0.041
reciprocal dna recombination GO:0035825 16 0.041
nucleobase containing small molecule metabolic process GO:0055086 352 0.041
protein polymerization GO:0051258 57 0.041
dna integrity checkpoint GO:0031570 28 0.040
histone threonine phosphorylation GO:0035405 1 0.039
microtubule polymerization or depolymerization GO:0031109 26 0.039
negative regulation of cell cycle process GO:0010948 69 0.038
establishment or maintenance of cell polarity GO:0007163 86 0.038
positive regulation of protein phosphorylation GO:0001934 242 0.038
regulation of exit from mitosis GO:0007096 1 0.037
positive regulation of cell development GO:0010720 237 0.037
lateral inhibition GO:0046331 1 0.037
regulation of attachment of spindle microtubules to kinetochore GO:0051988 3 0.036
Human
ras protein signal transduction GO:0007265 77 0.036
synaptonemal complex organization GO:0070193 15 0.036
positive regulation of organelle organization GO:0010638 128 0.036
oogenesis GO:0048477 56 0.035
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 31 0.035
ribonucleoside monophosphate catabolic process GO:0009158 57 0.035
regulation of microtubule depolymerization GO:0031114 13 0.035
cellular component assembly involved in morphogenesis GO:0010927 139 0.035
nucleoside phosphate metabolic process GO:0006753 338 0.034
membrane organization GO:0061024 245 0.033
mitotic cell cycle checkpoint GO:0007093 31 0.033
regulation of apoptotic signaling pathway GO:2001233 197 0.033
developmental maturation GO:0021700 193 0.033
cell cycle g2 m phase transition GO:0044839 20 0.032
nucleotide catabolic process GO:0009166 217 0.032
positive regulation of mitotic cell cycle phase transition GO:1901992 17 0.032
protein localization to chromosome centromeric region GO:0071459 1 0.032
cell fate commitment GO:0045165 210 0.032
negative regulation of proteolysis GO:0045861 74 0.032
atp metabolic process GO:0046034 75 0.031
positive regulation of transferase activity GO:0051347 167 0.031
regulation of double strand break repair via homologous recombination GO:0010569 2 0.031
actomyosin structure organization GO:0031032 56 0.031
negative regulation of mitotic metaphase anaphase transition GO:0045841 7 0.030
positive regulation of cellular amine metabolic process GO:0033240 5 0.030
positive regulation of nucleotide metabolic process GO:0045981 114 0.029
regulation of anatomical structure size GO:0090066 178 0.029
protein ubiquitination GO:0016567 171 0.029
response to light stimulus GO:0009416 135 0.029
mitotic sister chromatid cohesion GO:0007064 1 0.028
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 22 0.028
regulation of protein localization GO:0032880 231 0.028
Human
negative regulation of phosphorus metabolic process GO:0010563 184 0.028
regulation of meiosis i GO:0060631 7 0.028
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.028
regulation of transferase activity GO:0051338 263 0.027
positive regulation of protein catabolic process GO:0045732 60 0.027
microtubule anchoring GO:0034453 9 0.027
Human
nucleoside monophosphate metabolic process GO:0009123 85 0.026
protein processing GO:0016485 163 0.026
genitalia development GO:0048806 37 0.026
chromatin remodeling at centromere GO:0031055 2 0.026
regulation of ubiquitin protein transferase activity GO:0051438 7 0.026
female gamete generation GO:0007292 74 0.026
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 23 0.025
dna packaging GO:0006323 30 0.025
regulation of mitotic sister chromatid separation GO:0010965 12 0.025
maintenance of location in cell GO:0051651 24 0.025
Human
regulation of cellular amine metabolic process GO:0033238 20 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.025
protein localization to organelle GO:0033365 185 0.025
positive regulation of proteolysis GO:0045862 85 0.025
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.024
protein modification by small protein conjugation or removal GO:0070647 207 0.024
positive regulation of apoptotic process GO:0043065 217 0.024
membrane disassembly GO:0030397 1 0.024
regulation of nuclear division GO:0051783 56 0.024
Fly
peptidyl amino acid modification GO:0018193 336 0.024
regulation of cell projection organization GO:0031344 206 0.024
nucleoside monophosphate catabolic process GO:0009125 59 0.024
negative regulation of mitotic sister chromatid segregation GO:0033048 7 0.024
meiotic dna repair synthesis GO:0000711 4 0.024
regulation of dna dependent dna replication GO:0090329 8 0.023
protein complex disassembly GO:0043241 40 0.023
gland development GO:0048732 330 0.023
recombinational repair GO:0000725 21 0.023
myosin filament assembly GO:0031034 2 0.023
germline cell cycle switching mitotic to meiotic cell cycle GO:0051729 1 0.023
cellular amine metabolic process GO:0044106 44 0.023
negative regulation of protein maturation GO:1903318 79 0.023
negative regulation of protein modification process GO:0031400 163 0.023
peptidyl threonine modification GO:0018210 31 0.023
regulation of synaptic plasticity GO:0048167 87 0.022
positive regulation of cell division GO:0051781 31 0.022
embryonic epithelial tube formation GO:0001838 130 0.022
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.022
negative regulation of protein catabolic process GO:0042177 36 0.022
nuclear dna replication GO:0033260 3 0.021
g1 s transition of mitotic cell cycle GO:0000082 57 0.021
cellular response to ionizing radiation GO:0071479 11 0.021
positive regulation of kinase activity GO:0033674 155 0.021
chromosome condensation GO:0030261 10 0.021
cation transport GO:0006812 399 0.021
protein localization to chromosome GO:0034502 6 0.021
regulation of protein depolymerization GO:1901879 26 0.020
regulation of cell size GO:0008361 72 0.020
cellular ketone metabolic process GO:0042180 84 0.020
regulation of protein complex assembly GO:0043254 83 0.020
positive regulation of hydrolase activity GO:0051345 148 0.020
positive regulation of metaphase anaphase transition of cell cycle GO:1902101 2 0.020
negative regulation of meiotic cell cycle phase transition GO:1901994 3 0.020
positive regulation of nervous system development GO:0051962 221 0.020
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.020
peptidyl threonine phosphorylation GO:0018107 31 0.019
regulation of neuron differentiation GO:0045664 281 0.019
negative regulation of protein phosphorylation GO:0001933 126 0.019
protein autophosphorylation GO:0046777 61 0.019
Human
stem cell development GO:0048864 219 0.019
regulation of cellular ketone metabolic process GO:0010565 66 0.019
amine metabolic process GO:0009308 45 0.019
negative regulation of cell proliferation GO:0008285 296 0.018
negative regulation of phosphate metabolic process GO:0045936 184 0.018
regulation of ubiquitin protein ligase activity involved in mitotic cell cycle GO:0051439 1 0.018
mitotic spindle checkpoint GO:0071174 9 0.018
cellular response to biotic stimulus GO:0071216 92 0.018
wnt signaling pathway GO:0016055 188 0.018
Fly
multicellular organism growth GO:0035264 161 0.018
blood vessel morphogenesis GO:0048514 285 0.018
response to organic cyclic compound GO:0014070 198 0.017
regulation of protein binding GO:0043393 60 0.017
innate immune response GO:0045087 157 0.017
negative regulation of protein depolymerization GO:1901880 21 0.017
neuron migration GO:0001764 122 0.017
regulation of cellular amino acid metabolic process GO:0006521 5 0.017
protein maturation GO:0051604 176 0.017
regulation of dna replication GO:0006275 17 0.017
activation of anaphase promoting complex activity GO:0051488 1 0.017
positive regulation of programmed cell death GO:0043068 218 0.017
positive regulation of chromosome organization GO:2001252 33 0.017
positive regulation of synaptic plasticity GO:0031915 4 0.017
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.017
chromosome organization involved in meiosis GO:0070192 39 0.016
muscle cell differentiation GO:0042692 261 0.016
regulation of sister chromatid segregation GO:0033045 13 0.016
maintenance of protein location in cell GO:0032507 20 0.016
Human
myosin filament organization GO:0031033 3 0.016
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.016
gtp metabolic process GO:0046039 144 0.016
dna dependent dna replication GO:0006261 24 0.016
regulation of protein complex disassembly GO:0043244 28 0.016
striated muscle myosin thick filament assembly GO:0071688 1 0.016
mapk cascade GO:0000165 281 0.016
actin polymerization or depolymerization GO:0008154 54 0.016
reactive oxygen species metabolic process GO:0072593 84 0.016
meiotic spindle organization GO:0000212 9 0.015
nuclear envelope organization GO:0006998 11 0.015
female meiosis i GO:0007144 7 0.015
spermatid development GO:0007286 108 0.015
regulation of response to dna damage stimulus GO:2001020 34 0.015
phagocytosis GO:0006909 66 0.015
regulation of dephosphorylation GO:0035303 18 0.015
macromolecular complex disassembly GO:0032984 43 0.015
regulation of purine nucleotide metabolic process GO:1900542 169 0.014
cellular response to organonitrogen compound GO:0071417 145 0.014
neural tube formation GO:0001841 108 0.014
oocyte development GO:0048599 33 0.014
regulation of stem cell proliferation GO:0072091 78 0.014
anatomical structure homeostasis GO:0060249 145 0.014
single organism nuclear import GO:1902593 95 0.014
response to uv GO:0009411 44 0.014
spermatid differentiation GO:0048515 115 0.014
neural tube development GO:0021915 160 0.014
cell adhesion GO:0007155 329 0.014
regulation of mitotic metaphase anaphase transition GO:0030071 8 0.014
divalent inorganic cation transport GO:0072511 178 0.013
establishment of mitotic spindle orientation GO:0000132 12 0.013
negative regulation of transcription involved in g1 s transition of mitotic cell cycle GO:0071930 1 0.013
monocarboxylic acid metabolic process GO:0032787 191 0.013
signal transduction by p53 class mediator GO:0072331 51 0.013
negative regulation of apoptotic signaling pathway GO:2001234 104 0.013
guanosine containing compound catabolic process GO:1901069 144 0.013
regulation of purine nucleotide catabolic process GO:0033121 122 0.013
negative regulation of mitotic sister chromatid separation GO:2000816 7 0.013
protein polyubiquitination GO:0000209 33 0.013
regulation of cellular component biogenesis GO:0044087 181 0.013
response to inorganic substance GO:0010035 96 0.013
cellular lipid metabolic process GO:0044255 323 0.013
positive regulation of nucleotide catabolic process GO:0030813 88 0.013
actin filament organization GO:0007015 113 0.013
cell cycle switching mitotic to meiotic cell cycle GO:0051728 1 0.013
regulation of hydrolase activity GO:0051336 246 0.013
microtubule sliding GO:0051012 1 0.013
negative regulation of molecular function GO:0044092 258 0.012
cell maturation GO:0048469 127 0.012
protein localization to chromatin GO:0071168 3 0.012
negative regulation of cell division GO:0051782 24 0.012
regulation of cell cycle g1 s phase transition GO:1902806 35 0.012
humoral immune response GO:0006959 57 0.012
male meiosis chromosome segregation GO:0007060 3 0.012
regulation of ras gtpase activity GO:0032318 88 0.012
gtp catabolic process GO:0006184 143 0.012
regulation of actin filament based process GO:0032970 99 0.012
regulation of reactive oxygen species metabolic process GO:2000377 40 0.012
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.012
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.012
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.012
epithelial cell proliferation GO:0050673 174 0.012
regulation of auditory receptor cell differentiation GO:0045607 4 0.012
positive regulation of gtp catabolic process GO:0033126 85 0.012
response to iron ion GO:0010039 4 0.012
mesodermal cell migration GO:0008078 4 0.012
negative regulation of intracellular signal transduction GO:1902532 167 0.012
microtubule based transport GO:0010970 50 0.012
regulation of cytokine production GO:0001817 266 0.012
nucleus organization GO:0006997 45 0.012
regulation of t cell activation GO:0050863 170 0.011
actin filament polymerization GO:0030041 44 0.011
synaptic transmission GO:0007268 329 0.011
regulation of nucleotide metabolic process GO:0006140 169 0.011
negative regulation of nuclear division GO:0051784 19 0.011
regulation of intracellular transport GO:0032386 159 0.011
guanosine containing compound metabolic process GO:1901068 144 0.011
protein targeting GO:0006605 143 0.011
regulation of neural precursor cell proliferation GO:2000177 70 0.011
positive regulation of cell death GO:0010942 224 0.011
digestive system development GO:0055123 200 0.011
divalent metal ion transport GO:0070838 172 0.011
cell type specific apoptotic process GO:0097285 268 0.011
regulation of rho protein signal transduction GO:0035023 71 0.011
centromere complex assembly GO:0034508 3 0.011
regulation of centriole replication GO:0046599 1 0.011
meiotic chromosome condensation GO:0010032 3 0.011
lymphocyte differentiation GO:0030098 242 0.011
protein import GO:0017038 101 0.011
cellular homeostasis GO:0019725 240 0.011
epithelial tube morphogenesis GO:0060562 303 0.010
homeostasis of number of cells GO:0048872 210 0.010
dna catabolic process exonucleolytic GO:0000738 3 0.010
mitotic cell cycle embryonic GO:0045448 5 0.010
oxidation reduction process GO:0055114 342 0.010
spindle assembly involved in female meiosis i GO:0007057 2 0.010
regulation of mapk cascade GO:0043408 248 0.010
asymmetric stem cell division GO:0098722 3 0.010
positive regulation of mitosis GO:0045840 14 0.010
regulation of cell activation GO:0050865 289 0.010
dna biosynthetic process GO:0071897 22 0.010
membrane tubulation GO:0097320 4 0.010
dna geometric change GO:0032392 7 0.010
regulation of nucleotide catabolic process GO:0030811 122 0.010

Nek2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.084
disease of cellular proliferation DOID:14566 0 0.084
organ system cancer DOID:0050686 0 0.061
breast cancer DOID:1612 0 0.035
thoracic cancer DOID:5093 0 0.035
congenital hypoplastic anemia DOID:1342 0 0.034
immune system disease DOID:2914 0 0.034
aplastic anemia DOID:12449 0 0.034
disease of anatomical entity DOID:7 0 0.034
bone marrow disease DOID:4961 0 0.034
anemia DOID:2355 0 0.034
hematopoietic system disease DOID:74 0 0.034
gastrointestinal system cancer DOID:3119 0 0.012
intestinal cancer DOID:10155 0 0.012
physical disorder DOID:0080015 0 0.010