Mus musculus

0 known processes

Nek9

NIMA (never in mitosis gene a)-related expressed kinase 9

(Aliases: C130021H08Rik)

Nek9 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ras protein signal transduction GO:0007265 77 0.208
retrograde transport endosome to golgi GO:0042147 2 0.175
small gtpase mediated signal transduction GO:0007264 97 0.102
macromolecule catabolic process GO:0009057 281 0.079
protein catabolic process GO:0030163 221 0.066
endomembrane system organization GO:0010256 147 0.065
regulation of cell projection organization GO:0031344 206 0.063
protein localization to membrane GO:0072657 108 0.060
apoptotic signaling pathway GO:0097190 306 0.059
regulation of ras protein signal transduction GO:0046578 114 0.057
cellular ketone metabolic process GO:0042180 84 0.056
ribonucleotide metabolic process GO:0009259 291 0.055
negative regulation of protein metabolic process GO:0051248 282 0.053
cation transport GO:0006812 399 0.052
cellular amino acid metabolic process GO:0006520 103 0.052
cellular response to organonitrogen compound GO:0071417 145 0.051
nucleotide metabolic process GO:0009117 332 0.050
cellular response to salt stress GO:0071472 1 0.048
purine ribonucleotide metabolic process GO:0009150 290 0.047
peptidyl amino acid modification GO:0018193 336 0.046
membrane organization GO:0061024 245 0.046
transmembrane transport GO:0055085 412 0.045
regulation of cellular amine metabolic process GO:0033238 20 0.041
dephosphorylation GO:0016311 129 0.038
plasma membrane organization GO:0007009 90 0.037
negative regulation of cellular component organization GO:0051129 194 0.035
chemotaxis GO:0006935 247 0.035
rab protein signal transduction GO:0032482 1 0.035
cellular response to insulin stimulus GO:0032869 78 0.035
nucleobase containing small molecule metabolic process GO:0055086 352 0.035
aromatic compound catabolic process GO:0019439 286 0.034
cellular amine metabolic process GO:0044106 44 0.034
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.034
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.034
regulation of cellular ketone metabolic process GO:0010565 66 0.034
regulation of transferase activity GO:0051338 263 0.033
organelle localization GO:0051640 179 0.032
negative regulation of molecular function GO:0044092 258 0.031
positive regulation of cellular amine metabolic process GO:0033240 5 0.031
cation transmembrane transport GO:0098655 266 0.031
cell growth GO:0016049 130 0.031
regulation of neuron differentiation GO:0045664 281 0.030
positive regulation of apoptotic process GO:0043065 217 0.029
purine containing compound catabolic process GO:0072523 213 0.029
regulation of cell motility GO:2000145 236 0.029
hemangioblast cell differentiation GO:0060217 1 0.029
mapk cascade GO:0000165 281 0.029
regulation of cellular amino acid metabolic process GO:0006521 5 0.029
amine metabolic process GO:0009308 45 0.029
positive regulation of nervous system development GO:0051962 221 0.028
response to insulin GO:0032868 100 0.028
digestive system development GO:0055123 200 0.028
regulation of neuron projection development GO:0010975 169 0.028
nucleoside phosphate metabolic process GO:0006753 338 0.028
fertilization GO:0009566 127 0.028
rho protein signal transduction GO:0007266 32 0.028
mitotic cell cycle process GO:1903047 159 0.027
striated muscle tissue development GO:0014706 293 0.027
regulation of hydrolase activity GO:0051336 246 0.027
Mouse
ribonucleoside triphosphate metabolic process GO:0009199 220 0.026
cell junction organization GO:0034330 77 0.026
cellular component assembly involved in morphogenesis GO:0010927 139 0.026
cellular response to hormone stimulus GO:0032870 150 0.026
cellular macromolecule catabolic process GO:0044265 206 0.026
dna metabolic process GO:0006259 303 0.026
regulation of cellular response to stress GO:0080135 159 0.026
nucleoside phosphate catabolic process GO:1901292 222 0.026
negative regulation of phosphorylation GO:0042326 166 0.025
cellular response to biotic stimulus GO:0071216 92 0.025
organonitrogen compound catabolic process GO:1901565 264 0.025
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.025
transmission of nerve impulse GO:0019226 76 0.024
guanosine containing compound metabolic process GO:1901068 144 0.024
response to growth factor GO:0070848 198 0.024
intrinsic apoptotic signaling pathway GO:0097193 132 0.024
cellular response to dna damage stimulus GO:0006974 207 0.024
nucleoside triphosphate metabolic process GO:0009141 230 0.024
purine nucleotide metabolic process GO:0006163 302 0.024
regulation of cell cycle process GO:0010564 160 0.024
endocytosis GO:0006897 168 0.024
regulation of purine nucleotide catabolic process GO:0033121 122 0.023
negative regulation of protein modification process GO:0031400 163 0.023
lipid biosynthetic process GO:0008610 179 0.023
ribose phosphate metabolic process GO:0019693 291 0.023
actin cytoskeleton organization GO:0030036 220 0.023
peptidyl serine modification GO:0018209 83 0.023
gastrulation GO:0007369 116 0.023
positive regulation of programmed cell death GO:0043068 218 0.023
cellular response to peptide GO:1901653 92 0.023
carbohydrate derivative catabolic process GO:1901136 231 0.022
heterocycle catabolic process GO:0046700 280 0.022
regulation of cellular component biogenesis GO:0044087 181 0.022
protein modification by small protein conjugation or removal GO:0070647 207 0.022
negative regulation of cell proliferation GO:0008285 296 0.022
purine nucleoside triphosphate metabolic process GO:0009144 226 0.022
nucleotide catabolic process GO:0009166 217 0.022
response to oxidative stress GO:0006979 123 0.022
reactive oxygen species metabolic process GO:0072593 84 0.021
protein ubiquitination GO:0016567 171 0.021
cell adhesion GO:0007155 329 0.021
muscle tissue development GO:0060537 308 0.021
response to light stimulus GO:0009416 135 0.021
protein modification by small protein conjugation GO:0032446 187 0.021
purine nucleoside catabolic process GO:0006152 205 0.021
cytokinetic process GO:0032506 2 0.021
cellular lipid metabolic process GO:0044255 323 0.021
cellular response to growth factor stimulus GO:0071363 197 0.021
organic cyclic compound catabolic process GO:1901361 295 0.020
inorganic ion transmembrane transport GO:0098660 234 0.020
positive regulation of transferase activity GO:0051347 167 0.020
negative regulation of protein phosphorylation GO:0001933 126 0.020
regulation of mapk cascade GO:0043408 248 0.020
positive regulation of cellular catabolic process GO:0031331 148 0.020
regulation of cell activation GO:0050865 289 0.020
regulation of cellular catabolic process GO:0031329 242 0.020
nucleoside triphosphate catabolic process GO:0009143 205 0.020
stem cell differentiation GO:0048863 268 0.020
lymphocyte proliferation GO:0046651 164 0.020
regulation of response to wounding GO:1903034 189 0.020
positive regulation of cell death GO:0010942 224 0.020
regulation of ion transport GO:0043269 215 0.020
ribonucleoside triphosphate catabolic process GO:0009203 199 0.020
action potential GO:0001508 78 0.020
inorganic cation transmembrane transport GO:0098662 207 0.020
organelle assembly GO:0070925 177 0.019
protein processing GO:0016485 163 0.019
wound healing GO:0042060 157 0.019
myofibril assembly GO:0030239 34 0.019
single fertilization GO:0007338 82 0.019
negative regulation of hydrolase activity GO:0051346 71 0.019
regulation of cell growth GO:0001558 91 0.019
protein localization to plasma membrane GO:0072659 57 0.019
response to peptide hormone GO:0043434 127 0.019
purine ribonucleotide catabolic process GO:0009154 208 0.019
carbohydrate metabolic process GO:0005975 230 0.019
regulation of protein localization GO:0032880 231 0.019
regulation of protein maturation GO:1903317 96 0.019
digestive tract morphogenesis GO:0048546 147 0.019
regulation of protein processing GO:0070613 96 0.019
nucleoside metabolic process GO:0009116 246 0.018
regulation of organelle organization GO:0033043 289 0.018
regulation of mitotic cell cycle GO:0007346 126 0.018
regulation of cell cycle GO:0051726 281 0.018
peptidyl proline hydroxylation GO:0019511 3 0.018
positive regulation of protein phosphorylation GO:0001934 242 0.018
urogenital system development GO:0001655 261 0.018
microtubule based process GO:0007017 236 0.018
regulation of reactive oxygen species metabolic process GO:2000377 40 0.018
cellular nitrogen compound catabolic process GO:0044270 280 0.018
response to organonitrogen compound GO:0010243 246 0.018
regulation of apoptotic signaling pathway GO:2001233 197 0.018
maintenance of location GO:0051235 89 0.018
protein maturation GO:0051604 176 0.018
regulation of proteolysis GO:0030162 164 0.017
Mouse
ion transmembrane transport GO:0034220 361 0.017
skeletal muscle organ development GO:0060538 163 0.017
actomyosin structure organization GO:0031032 56 0.017
positive regulation of hydrolase activity GO:0051345 148 0.017
Mouse
negative regulation of intracellular signal transduction GO:1902532 167 0.017
peptidyl serine phosphorylation GO:0018105 74 0.017
negative regulation of cellular protein metabolic process GO:0032269 247 0.017
purine ribonucleoside metabolic process GO:0046128 241 0.017
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.017
developmental growth involved in morphogenesis GO:0060560 138 0.017
ribonucleotide catabolic process GO:0009261 208 0.017
cellular response to peptide hormone stimulus GO:0071375 92 0.017
regulation of membrane potential GO:0042391 192 0.017
positive regulation of nucleotide metabolic process GO:0045981 114 0.017
compound eye development GO:0048749 1 0.017
modification dependent protein catabolic process GO:0019941 133 0.017
glycosyl compound catabolic process GO:1901658 206 0.016
muscle cell development GO:0055001 133 0.016
positive regulation of cell development GO:0010720 237 0.016
male gamete generation GO:0048232 285 0.016
negative regulation of phosphate metabolic process GO:0045936 184 0.016
regulation of purine nucleotide metabolic process GO:1900542 169 0.016
nitrogen compound transport GO:0071705 271 0.016
positive regulation of dna templated transcription elongation GO:0032786 2 0.016
posttranscriptional regulation of gene expression GO:0010608 155 0.016
negative regulation of mitotic cell cycle GO:0045930 58 0.016
cellular protein catabolic process GO:0044257 155 0.016
carbohydrate derivative biosynthetic process GO:1901137 183 0.016
purine nucleoside metabolic process GO:0042278 241 0.016
ribonucleoside metabolic process GO:0009119 245 0.016
mitochondrion organization GO:0007005 134 0.016
regulation of protein serine threonine kinase activity GO:0071900 157 0.016
establishment of organelle localization GO:0051656 122 0.016
potassium ion transport GO:0006813 52 0.016
modification dependent macromolecule catabolic process GO:0043632 133 0.016
regulation of multi organism process GO:0043900 111 0.016
interleukin 8 production GO:0032637 4 0.016
positive regulation of neuron differentiation GO:0045666 141 0.016
sensory perception GO:0007600 245 0.016
protein autophosphorylation GO:0046777 61 0.016
negative regulation of cell development GO:0010721 169 0.015
regulation of interleukin 8 production GO:0032677 3 0.015
cytokine production GO:0001816 319 0.015
response to inorganic substance GO:0010035 96 0.015
regulation of anatomical structure size GO:0090066 178 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.015
regulation of cytokine production GO:0001817 266 0.015
p38mapk cascade GO:0038066 4 0.015
divalent inorganic cation transport GO:0072511 178 0.015
axonogenesis GO:0007409 274 0.015
multicellular organismal signaling GO:0035637 91 0.015
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.015
cellular carbohydrate metabolic process GO:0044262 119 0.015
regulation of cell migration GO:0030334 219 0.015
regulation of mitotic cell cycle phase transition GO:1901990 73 0.015
negative regulation of protein maturation GO:1903318 79 0.015
negative regulation of cell cycle GO:0045786 123 0.015
protein localization to organelle GO:0033365 185 0.014
anion transport GO:0006820 177 0.014
regulation of ras gtpase activity GO:0032318 88 0.014
regulation of nucleoside metabolic process GO:0009118 130 0.014
mitotic cell cycle GO:0000278 195 0.014
positive regulation of cell motility GO:2000147 116 0.014
single organism cell adhesion GO:0098602 156 0.014
purine nucleotide catabolic process GO:0006195 211 0.014
regulation of protein kinase activity GO:0045859 232 0.014
gonad development GO:0008406 141 0.014
tissue remodeling GO:0048771 102 0.014
renal system development GO:0072001 225 0.014
cellular homeostasis GO:0019725 240 0.014
g1 s transition of mitotic cell cycle GO:0000082 57 0.014
negative regulation of neuron differentiation GO:0045665 101 0.014
phagocytosis GO:0006909 66 0.014
cell division GO:0051301 120 0.014
exocytosis GO:0006887 121 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.014
regulation of establishment of protein localization GO:0070201 181 0.014
learning or memory GO:0007611 148 0.014
digestive tract development GO:0048565 190 0.014
regulation of secretion by cell GO:1903530 249 0.014
negative regulation of growth GO:0045926 99 0.014
cell type specific apoptotic process GO:0097285 268 0.014
synaptic transmission GO:0007268 329 0.014
cytoplasmic transport GO:0016482 234 0.014
innate immune response GO:0045087 157 0.014
regulation of cytoskeleton organization GO:0051493 122 0.014
anatomical structure homeostasis GO:0060249 145 0.013
spermatogenesis GO:0007283 284 0.013
glycosylation GO:0070085 62 0.013
organophosphate biosynthetic process GO:0090407 122 0.013
t cell activation GO:0042110 289 0.013
negative regulation of phosphorus metabolic process GO:0010563 184 0.013
divalent metal ion transport GO:0070838 172 0.013
purine nucleoside triphosphate catabolic process GO:0009146 203 0.013
ribonucleoside catabolic process GO:0042454 206 0.013
positive regulation of protein modification process GO:0031401 299 0.013
development of primary sexual characteristics GO:0045137 143 0.013
response to organic cyclic compound GO:0014070 198 0.013
ossification GO:0001503 216 0.013
extracellular matrix organization GO:0030198 147 0.013
negative regulation of cell projection organization GO:0031345 56 0.013
negative regulation of cellular amine metabolic process GO:0033239 1 0.013
positive regulation of cell activation GO:0050867 158 0.013
muscle cell differentiation GO:0042692 261 0.013
Mouse
multicellular organism growth GO:0035264 161 0.013
myotube differentiation GO:0014902 105 0.013
b cell activation GO:0042113 161 0.013
formation of primary germ layer GO:0001704 77 0.013
germ cell development GO:0007281 185 0.013
purine containing compound metabolic process GO:0072521 311 0.013
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.013
regulation of excitatory postsynaptic membrane potential GO:0060079 41 0.013
leukocyte mediated immunity GO:0002443 174 0.013
response to osmotic stress GO:0006970 21 0.012
negative regulation of organelle organization GO:0010639 90 0.012
positive regulation of neuron projection development GO:0010976 79 0.012
positive regulation of growth GO:0045927 104 0.012
leukocyte differentiation GO:0002521 342 0.012
regulation of innate immune response GO:0045088 91 0.012
leukocyte proliferation GO:0070661 172 0.012
regulation of metal ion transport GO:0010959 106 0.012
nucleocytoplasmic transport GO:0006913 139 0.012
neuron death GO:0070997 154 0.012
reactive oxygen species biosynthetic process GO:1903409 8 0.012
nuclear transport GO:0051169 139 0.012
negative regulation of proteolysis GO:0045861 74 0.012
positive regulation of homeostatic process GO:0032846 64 0.012
nucleoside catabolic process GO:0009164 206 0.012
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.012
dna repair GO:0006281 107 0.012
dendrite development GO:0016358 115 0.012
stem cell development GO:0048864 219 0.012
circulatory system process GO:0003013 197 0.012
cellular response to abiotic stimulus GO:0071214 56 0.012
regulation of lymphocyte activation GO:0051249 240 0.012
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.012
regulation of protein catabolic process GO:0042176 108 0.012
positive regulation of mapk cascade GO:0043410 170 0.012
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.012
actin filament organization GO:0007015 113 0.012
regulation of jnk cascade GO:0046328 62 0.012
immune effector process GO:0002252 321 0.012
regulation of defense response GO:0031347 233 0.012
response to extracellular stimulus GO:0009991 127 0.012
neuronal action potential GO:0019228 54 0.012
cellular chemical homeostasis GO:0055082 215 0.012
regulation of cell cycle phase transition GO:1901987 77 0.012
regulation of homeostatic process GO:0032844 182 0.011
cellular response to acid chemical GO:0071229 68 0.011
cell cycle g1 s phase transition GO:0044843 57 0.011
positive regulation of gtp catabolic process GO:0033126 85 0.011
negative regulation of cell cycle phase transition GO:1901988 48 0.011
negative regulation of cell cycle process GO:0010948 69 0.011
cell junction assembly GO:0034329 52 0.011
guanosine containing compound catabolic process GO:1901069 144 0.011
mesoderm formation GO:0001707 62 0.011
negative regulation of neuron projection development GO:0010977 50 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.011
organonitrogen compound biosynthetic process GO:1901566 192 0.011
sequestering of calcium ion GO:0051208 18 0.011
regulation of actin cytoskeleton organization GO:0032956 84 0.011
stress activated mapk cascade GO:0051403 80 0.011
regulation of nucleotide metabolic process GO:0006140 169 0.011
cellular ion homeostasis GO:0006873 165 0.011
adaptive immune response GO:0002250 155 0.011
nuclear division GO:0000280 158 0.011
positive regulation of ras gtpase activity GO:0032320 65 0.011
regulation of synaptic plasticity GO:0048167 87 0.011
striated muscle cell development GO:0055002 125 0.011
lipid localization GO:0010876 126 0.011
cell fate commitment GO:0045165 210 0.011
positive regulation of cell migration GO:0030335 109 0.011
regulation of reproductive process GO:2000241 66 0.011
ensheathment of neurons GO:0007272 76 0.011
glycosyl compound metabolic process GO:1901657 246 0.010
regulation of kinase activity GO:0043549 249 0.010
regulation of vesicle mediated transport GO:0060627 139 0.010
response to uv GO:0009411 44 0.010
regulation of transmembrane transport GO:0034762 128 0.010
vesicle localization GO:0051648 86 0.010
positive regulation of glycolytic process GO:0045821 4 0.010
negative regulation of protein processing GO:0010955 79 0.010
sequestering of metal ion GO:0051238 19 0.010
lymphocyte differentiation GO:0030098 242 0.010
golgi vesicle transport GO:0048193 30 0.010
regulation of system process GO:0044057 200 0.010
positive regulation of gtpase activity GO:0043547 85 0.010
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.010
defense response to bacterium GO:0042742 119 0.010
regulation of intracellular transport GO:0032386 159 0.010
oxidation reduction process GO:0055114 342 0.010

Nek9 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.035
inherited metabolic disorder DOID:655 0 0.020
disease of anatomical entity DOID:7 0 0.018
nervous system disease DOID:863 0 0.018
musculoskeletal system disease DOID:17 0 0.016
bone disease DOID:0080001 0 0.014
connective tissue disease DOID:65 0 0.014
sensory system disease DOID:0050155 0 0.013
immune system disease DOID:2914 0 0.011