Mus musculus

172 known processes

Senp2

SUMO/sentrin specific peptidase 2

(Aliases: KIAA1331,AW554757,Smt3ip2,mKIAA1331,2310007L05Rik,AI646780,4930538C18Rik,SuPr-1)

Senp2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein localization to nucleus GO:0034504 121 0.162
protein modification by small protein conjugation GO:0032446 187 0.154
cellular amino acid metabolic process GO:0006520 103 0.134
cellular ketone metabolic process GO:0042180 84 0.099
protein modification by small protein conjugation or removal GO:0070647 207 0.096
cellular amine metabolic process GO:0044106 44 0.087
amine metabolic process GO:0009308 45 0.086
ribonucleoside catabolic process GO:0042454 206 0.085
rna processing GO:0006396 105 0.078
ras protein signal transduction GO:0007265 77 0.075
protein ubiquitination GO:0016567 171 0.070
regulation of cell cycle GO:0051726 281 0.064
mitotic cell cycle GO:0000278 195 0.063
protein localization to organelle GO:0033365 185 0.063
purine containing compound metabolic process GO:0072521 311 0.057
regulation of cellular catabolic process GO:0031329 242 0.057
Mouse
regulation of cellular ketone metabolic process GO:0010565 66 0.056
regulation of apoptotic signaling pathway GO:2001233 197 0.055
nucleobase containing small molecule metabolic process GO:0055086 352 0.052
nuclear import GO:0051170 95 0.052
protein import GO:0017038 101 0.051
protein autophosphorylation GO:0046777 61 0.050
nucleocytoplasmic transport GO:0006913 139 0.049
cellular response to dna damage stimulus GO:0006974 207 0.049
organonitrogen compound biosynthetic process GO:1901566 192 0.048
intracellular protein transport GO:0006886 204 0.047
protein targeting GO:0006605 143 0.047
regulation of cytoplasmic transport GO:1903649 112 0.045
negative regulation of response to dna damage stimulus GO:2001021 10 0.045
modification dependent protein catabolic process GO:0019941 133 0.044
Mouse
organic cyclic compound catabolic process GO:1901361 295 0.044
purine ribonucleotide metabolic process GO:0009150 290 0.044
negative regulation of dna damage response signal transduction by p53 class mediator GO:0043518 5 0.044
nuclear transport GO:0051169 139 0.043
glycerolipid metabolic process GO:0046486 122 0.042
regulation of protein transport GO:0051223 163 0.042
nucleoside metabolic process GO:0009116 246 0.040
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.040
Mouse
posttranscriptional regulation of gene expression GO:0010608 155 0.040
glycerolipid biosynthetic process GO:0045017 50 0.040
regulation of nucleotide metabolic process GO:0006140 169 0.039
negative regulation of intracellular signal transduction GO:1902532 167 0.038
alpha amino acid metabolic process GO:1901605 59 0.037
protein import into nucleus GO:0006606 95 0.036
regulation of protein stability GO:0031647 52 0.036
peptidyl amino acid modification GO:0018193 336 0.036
regulation of intracellular transport GO:0032386 159 0.036
macromolecule catabolic process GO:0009057 281 0.036
Mouse
amp metabolic process GO:0046033 4 0.036
cellular lipid metabolic process GO:0044255 323 0.035
organonitrogen compound catabolic process GO:1901565 264 0.035
nucleotide metabolic process GO:0009117 332 0.034
regulation of protein localization GO:0032880 231 0.034
regulation of cellular amine metabolic process GO:0033238 20 0.033
heterocycle catabolic process GO:0046700 280 0.033
purine nucleoside metabolic process GO:0042278 241 0.032
transmission of nerve impulse GO:0019226 76 0.032
positive regulation of cellular amine metabolic process GO:0033240 5 0.032
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.032
cellular modified amino acid metabolic process GO:0006575 63 0.031
negative regulation of cell cycle arrest GO:0071157 1 0.031
establishment of protein localization to organelle GO:0072594 118 0.031
cellular carbohydrate metabolic process GO:0044262 119 0.030
positive regulation of mesoderm development GO:2000382 2 0.030
positive regulation of intracellular transport GO:0032388 70 0.030
cation transport GO:0006812 399 0.029
regulation of intracellular protein transport GO:0033157 82 0.029
homeostasis of number of cells GO:0048872 210 0.028
Mouse
response to reactive oxygen species GO:0000302 56 0.028
germline cell cycle switching mitotic to meiotic cell cycle GO:0051729 1 0.028
positive regulation of intracellular protein transport GO:0090316 42 0.028
aromatic compound catabolic process GO:0019439 286 0.027
carbohydrate derivative biosynthetic process GO:1901137 183 0.027
cellular nitrogen compound catabolic process GO:0044270 280 0.027
single organism nuclear import GO:1902593 95 0.027
regulation of nucleocytoplasmic transport GO:0046822 73 0.027
lipid biosynthetic process GO:0008610 179 0.027
apoptotic signaling pathway GO:0097190 306 0.027
neuronal action potential GO:0019228 54 0.027
nucleoside catabolic process GO:0009164 206 0.027
ribonucleoside triphosphate catabolic process GO:0009203 199 0.026
male gamete generation GO:0048232 285 0.026
skeletal system development GO:0001501 356 0.026
transmembrane transport GO:0055085 412 0.026
cytoplasmic transport GO:0016482 234 0.026
positive regulation of protein modification process GO:0031401 299 0.026
protein catabolic process GO:0030163 221 0.025
Mouse
ubiquitin dependent protein catabolic process GO:0006511 129 0.025
Mouse
regulation of protein catabolic process GO:0042176 108 0.024
Mouse
regulation of protein targeting GO:1903533 61 0.024
carbohydrate metabolic process GO:0005975 230 0.024
regulation of muscle tissue development GO:1901861 97 0.024
positive regulation of protein phosphorylation GO:0001934 242 0.024
dephosphorylation GO:0016311 129 0.024
regulation of protein import into nucleus GO:0042306 52 0.024
positive regulation of protein transport GO:0051222 93 0.023
engulfment of apoptotic cell GO:0043652 3 0.023
negative regulation of phosphate metabolic process GO:0045936 184 0.023
regulation of protein localization to nucleus GO:1900180 60 0.023
glycerophospholipid metabolic process GO:0006650 71 0.023
cell cycle switching mitotic to meiotic cell cycle GO:0051728 1 0.023
nuclear division GO:0000280 158 0.023
phospholipid metabolic process GO:0006644 87 0.023
neuron death GO:0070997 154 0.023
positive regulation of nucleotide metabolic process GO:0045981 114 0.023
signal transduction by p53 class mediator GO:0072331 51 0.022
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.022
regulation of map kinase activity GO:0043405 120 0.022
protein modification by small protein removal GO:0070646 21 0.022
peptidyl serine modification GO:0018209 83 0.022
purine ribonucleoside metabolic process GO:0046128 241 0.022
regulation of purine nucleotide catabolic process GO:0033121 122 0.022
spermatogenesis GO:0007283 284 0.021
cell type specific apoptotic process GO:0097285 268 0.021
single organism cell adhesion GO:0098602 156 0.021
asymmetric neuroblast division GO:0055059 1 0.021
protein polyubiquitination GO:0000209 33 0.021
endomembrane system organization GO:0010256 147 0.021
hexose metabolic process GO:0019318 98 0.021
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.021
small molecule catabolic process GO:0044282 71 0.020
multicellular organismal signaling GO:0035637 91 0.020
regulation of nucleotide catabolic process GO:0030811 122 0.020
response to growth factor GO:0070848 198 0.020
organic hydroxy compound metabolic process GO:1901615 203 0.020
regulation of establishment of protein localization GO:0070201 181 0.019
meiotic cell cycle process GO:1903046 77 0.019
cell adhesion GO:0007155 329 0.019
organelle localization GO:0051640 179 0.019
mapk cascade GO:0000165 281 0.019
positive regulation of cytoplasmic transport GO:1903651 40 0.019
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.019
nucleoside phosphate catabolic process GO:1901292 222 0.019
chromosome segregation GO:0007059 48 0.019
positive regulation of kinase activity GO:0033674 155 0.018
mitotic cell cycle process GO:1903047 159 0.018
regionalization GO:0003002 337 0.018
regulation of neuron death GO:1901214 134 0.018
nitrogen compound transport GO:0071705 271 0.018
regulation of hydrolase activity GO:0051336 246 0.018
ribonucleotide metabolic process GO:0009259 291 0.018
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.018
hexose biosynthetic process GO:0019319 39 0.018
oxidation reduction process GO:0055114 342 0.018
negative regulation of cellular protein metabolic process GO:0032269 247 0.018
Mouse
photoreceptor cell morphogenesis GO:0008594 3 0.018
membrane organization GO:0061024 245 0.018
glucose metabolic process GO:0006006 92 0.017
regulation of transferase activity GO:0051338 263 0.017
glucose homeostasis GO:0042593 128 0.017
negative regulation of mitotic cell cycle GO:0045930 58 0.017
maintenance of apical basal cell polarity GO:0035090 3 0.017
nucleoside phosphate metabolic process GO:0006753 338 0.017
germ cell development GO:0007281 185 0.017
purine nucleotide metabolic process GO:0006163 302 0.017
bone development GO:0060348 120 0.017
purine nucleoside catabolic process GO:0006152 205 0.017
ribose phosphate metabolic process GO:0019693 291 0.017
response to organonitrogen compound GO:0010243 246 0.017
positive regulation of protein localization to nucleus GO:1900182 30 0.017
monosaccharide biosynthetic process GO:0046364 44 0.017
ribonucleoside metabolic process GO:0009119 245 0.017
regulation of protein serine threonine kinase activity GO:0071900 157 0.016
positive regulation of cellular catabolic process GO:0031331 148 0.016
negative regulation of inclusion body assembly GO:0090084 1 0.016
regulation of response to wounding GO:1903034 189 0.016
Fly
monosaccharide metabolic process GO:0005996 106 0.016
asymmetric stem cell division GO:0098722 3 0.016
regulation of ras protein signal transduction GO:0046578 114 0.016
regulation of anatomical structure size GO:0090066 178 0.016
nucleus organization GO:0006997 45 0.016
ion transmembrane transport GO:0034220 361 0.016
vesicle localization GO:0051648 86 0.016
intracellular signal transduction involved in g1 dna damage checkpoint GO:1902400 3 0.016
positive regulation of protein kinase activity GO:0045860 144 0.015
peptidyl serine phosphorylation GO:0018105 74 0.015
reactive oxygen species metabolic process GO:0072593 84 0.015
multicellular organism growth GO:0035264 161 0.015
connective tissue development GO:0061448 179 0.015
regulation of cellular amino acid metabolic process GO:0006521 5 0.015
cellular homeostasis GO:0019725 240 0.015
compound eye development GO:0048749 1 0.015
regulation of proteolysis GO:0030162 164 0.015
Mouse
purine nucleotide catabolic process GO:0006195 211 0.015
wound healing GO:0042060 157 0.015
response to acid chemical GO:0001101 111 0.015
negative regulation of cell cycle GO:0045786 123 0.015
regulation of nucleoside metabolic process GO:0009118 130 0.015
endocytosis GO:0006897 168 0.015
carbohydrate biosynthetic process GO:0016051 74 0.014
transcription from rna polymerase iii promoter GO:0006383 3 0.014
small molecule biosynthetic process GO:0044283 132 0.014
inorganic ion transmembrane transport GO:0098660 234 0.014
positive regulation of mitotic sister chromatid separation GO:1901970 2 0.014
regulation of cell cycle process GO:0010564 160 0.014
peptidyl threonine modification GO:0018210 31 0.014
cdp choline pathway GO:0006657 2 0.014
alcohol metabolic process GO:0006066 116 0.014
mitochondrion organization GO:0007005 134 0.014
ribonucleotide catabolic process GO:0009261 208 0.014
regulation of defense response GO:0031347 233 0.014
Fly
cellular response to cadmium ion GO:0071276 3 0.014
regulation of purine nucleotide metabolic process GO:1900542 169 0.014
microtubule based process GO:0007017 236 0.014
morphogenesis of embryonic epithelium GO:0016331 159 0.013
cellular protein catabolic process GO:0044257 155 0.013
Mouse
small gtpase mediated signal transduction GO:0007264 97 0.013
macroautophagy GO:0016236 21 0.013
regulation of organelle organization GO:0033043 289 0.013
gtp catabolic process GO:0006184 143 0.013
response to epidermal growth factor GO:0070849 4 0.013
negative regulation of apoptotic signaling pathway GO:2001234 104 0.013
ribonucleoside triphosphate metabolic process GO:0009199 220 0.013
negative regulation of cell cycle process GO:0010948 69 0.013
negative regulation of molecular function GO:0044092 258 0.013
protein depolymerization GO:0051261 34 0.013
peptidyl threonine phosphorylation GO:0018107 31 0.013
response to lipopolysaccharide GO:0032496 128 0.013
striated muscle tissue development GO:0014706 293 0.013
phosphatidylethanolamine biosynthetic process GO:0006646 2 0.013
adult behavior GO:0030534 135 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.013
regulation of neuron apoptotic process GO:0043523 122 0.012
negative regulation of nervous system development GO:0051961 156 0.012
cellular response to epidermal growth factor stimulus GO:0071364 4 0.012
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 25 0.012
skeletal muscle organ development GO:0060538 163 0.012
misfolded protein transport GO:0070843 1 0.012
macromolecular complex disassembly GO:0032984 43 0.012
regulation of hormone levels GO:0010817 211 0.012
cell cycle switching GO:0060184 1 0.012
nodal signaling pathway involved in determination of left right asymmetry GO:0038107 2 0.012
inorganic cation transmembrane transport GO:0098662 207 0.012
mrna metabolic process GO:0016071 84 0.012
regulation of ion transport GO:0043269 215 0.012
cellular response to molecule of bacterial origin GO:0071219 83 0.012
cellular response to lipid GO:0071396 145 0.012
phagocytosis GO:0006909 66 0.012
protein complex disassembly GO:0043241 40 0.012
intrinsic apoptotic signaling pathway GO:0097193 132 0.012
rna splicing GO:0008380 54 0.012
muscle contraction GO:0006936 101 0.012
regulation of protein ubiquitination GO:0031396 52 0.012
amide transport GO:0042886 138 0.012
regulation of system process GO:0044057 200 0.012
skeletal system morphogenesis GO:0048705 203 0.012
divalent inorganic cation transport GO:0072511 178 0.012
response to oxidative stress GO:0006979 123 0.012
gland development GO:0048732 330 0.012
Fly
positive regulation of gtp catabolic process GO:0033126 85 0.012
ossification GO:0001503 216 0.012
positive regulation of nucleocytoplasmic transport GO:0046824 30 0.012
purine nucleoside triphosphate catabolic process GO:0009146 203 0.012
response to inorganic substance GO:0010035 96 0.011
response to radiation GO:0009314 165 0.011
action potential GO:0001508 78 0.011
dna repair GO:0006281 107 0.011
digestive system development GO:0055123 200 0.011
response to transforming growth factor beta GO:0071559 88 0.011
leukocyte differentiation GO:0002521 342 0.011
chromosome organization involved in meiosis GO:0070192 39 0.011
lipid localization GO:0010876 126 0.011
regulation of cellular response to stress GO:0080135 159 0.011
phosphorylated carbohydrate dephosphorylation GO:0046838 4 0.011
cellular response to growth factor stimulus GO:0071363 197 0.011
acylglycerol metabolic process GO:0006639 55 0.011
regulation of secretion GO:0051046 274 0.011
cellular response to oxygen levels GO:0071453 20 0.011
Fly
establishment of organelle localization GO:0051656 122 0.011
atp catabolic process GO:0006200 55 0.011
cellular amino acid catabolic process GO:0009063 25 0.011
regulation of myotube differentiation GO:0010830 62 0.011
muscle tissue development GO:0060537 308 0.011
organophosphate catabolic process GO:0046434 232 0.011
regulation of inclusion body assembly GO:0090083 1 0.011
regulation of lipid biosynthetic process GO:0046890 54 0.010
g protein coupled receptor signaling pathway GO:0007186 243 0.010
protein lipidation GO:0006497 28 0.010
muscle system process GO:0003012 141 0.010
carboxylic acid biosynthetic process GO:0046394 86 0.010
phosphatidylethanolamine metabolic process GO:0046337 2 0.010
cartilage development GO:0051216 140 0.010
sulfur compound metabolic process GO:0006790 100 0.010
muscle cell differentiation GO:0042692 261 0.010
regulation of protein kinase activity GO:0045859 232 0.010
regulation of mrna metabolic process GO:1903311 43 0.010
lipoprotein metabolic process GO:0042157 43 0.010
stress activated protein kinase signaling cascade GO:0031098 81 0.010
cellular response to external stimulus GO:0071496 88 0.010
regulation of cellular component biogenesis GO:0044087 181 0.010
cellular amide metabolic process GO:0043603 58 0.010
regulation of transcription from rna polymerase iii promoter GO:0006359 2 0.010
nucleoside triphosphate metabolic process GO:0009141 230 0.010
regulation of neuron differentiation GO:0045664 281 0.010
monocarboxylic acid metabolic process GO:0032787 191 0.010
response to granulocyte macrophage colony stimulating factor GO:0097012 3 0.010
spindle assembly involved in mitosis GO:0090307 4 0.010
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.010
positive regulation of apoptotic process GO:0043065 217 0.010
regulation of reactive oxygen species metabolic process GO:2000377 40 0.010

Senp2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
large intestine cancer DOID:5672 0 0.012
colon cancer DOID:219 0 0.012
gastrointestinal system cancer DOID:3119 0 0.012
intestinal cancer DOID:10155 0 0.012
cancer DOID:162 0 0.012
disease of cellular proliferation DOID:14566 0 0.012
organ system cancer DOID:0050686 0 0.012
colorectal cancer DOID:9256 0 0.012