Mus musculus

105 known processes

Senp1

SUMO1/sentrin specific peptidase 1

(Aliases: D15Ertd528e,2310046A20Rik,E330036L07Rik,MGC27975)

Senp1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cell cycle process GO:0010564 160 0.083
Mouse
organelle fission GO:0048285 170 0.081
cellular amino acid metabolic process GO:0006520 103 0.080
cellular ketone metabolic process GO:0042180 84 0.072
cellular response to dna damage stimulus GO:0006974 207 0.070
Mouse
mitotic cell cycle process GO:1903047 159 0.067
Mouse
regulation of cell cycle GO:0051726 281 0.063
Mouse
mitotic cell cycle GO:0000278 195 0.062
Mouse
microtubule based process GO:0007017 236 0.061
amine metabolic process GO:0009308 45 0.059
regulation of cellular amino acid metabolic process GO:0006521 5 0.059
cellular amine metabolic process GO:0044106 44 0.059
regulation of cellular amine metabolic process GO:0033238 20 0.058
regulation of cellular ketone metabolic process GO:0010565 66 0.056
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.053
nuclear division GO:0000280 158 0.052
meiotic cell cycle GO:0051321 122 0.051
dna metabolic process GO:0006259 303 0.048
Mouse
chromatin organization GO:0006325 206 0.045
regulation of organelle organization GO:0033043 289 0.042
positive regulation of cellular amine metabolic process GO:0033240 5 0.039
chromatin modification GO:0016568 187 0.038
negative regulation of cellular component organization GO:0051129 194 0.038
positive regulation of apoptotic process GO:0043065 217 0.036
Human
spermatogenesis GO:0007283 284 0.036
macromolecule catabolic process GO:0009057 281 0.035
methylation GO:0032259 134 0.034
peptidyl amino acid modification GO:0018193 336 0.032
gonad development GO:0008406 141 0.031
male gamete generation GO:0048232 285 0.031
negative regulation of organelle organization GO:0010639 90 0.031
microtubule cytoskeleton organization GO:0000226 157 0.031
dna repair GO:0006281 107 0.030
nitrogen compound transport GO:0071705 271 0.030
apoptotic signaling pathway GO:0097190 306 0.029
Human
cellular macromolecule catabolic process GO:0044265 206 0.028
meiotic nuclear division GO:0007126 115 0.028
regulation of cellular catabolic process GO:0031329 242 0.028
negative regulation of cell cycle GO:0045786 123 0.028
protein methylation GO:0006479 81 0.027
response to radiation GO:0009314 165 0.027
positive regulation of protein modification process GO:0031401 299 0.026
male meiosis GO:0007140 37 0.026
small gtpase mediated signal transduction GO:0007264 97 0.026
germ cell development GO:0007281 185 0.026
positive regulation of programmed cell death GO:0043068 218 0.025
Human
negative regulation of cell cycle process GO:0010948 69 0.025
protein maturation GO:0051604 176 0.025
membrane organization GO:0061024 245 0.024
immune effector process GO:0002252 321 0.024
regulation of apoptotic signaling pathway GO:2001233 197 0.023
regulation of cell division GO:0051302 76 0.023
protein modification by small protein conjugation GO:0032446 187 0.023
cation transport GO:0006812 399 0.023
protein alkylation GO:0008213 81 0.023
nucleoside metabolic process GO:0009116 246 0.023
development of primary sexual characteristics GO:0045137 143 0.023
protein catabolic process GO:0030163 221 0.022
cytoplasmic transport GO:0016482 234 0.022
regulation of membrane potential GO:0042391 192 0.022
regulation of cellular component biogenesis GO:0044087 181 0.021
covalent chromatin modification GO:0016569 163 0.021
negative regulation of protein metabolic process GO:0051248 282 0.021
aromatic compound catabolic process GO:0019439 286 0.021
oxidation reduction process GO:0055114 342 0.021
cellular protein complex assembly GO:0043623 116 0.021
heterocycle catabolic process GO:0046700 280 0.021
leukocyte differentiation GO:0002521 342 0.021
endomembrane system organization GO:0010256 147 0.020
ras protein signal transduction GO:0007265 77 0.020
histone methylation GO:0016571 71 0.020
cell division GO:0051301 120 0.020
rna processing GO:0006396 105 0.020
protein modification by small protein conjugation or removal GO:0070647 207 0.020
positive regulation of cell death GO:0010942 224 0.020
Human
response to organonitrogen compound GO:0010243 246 0.020
macromolecule methylation GO:0043414 120 0.020
ion transmembrane transport GO:0034220 361 0.020
regulation of mitotic cell cycle GO:0007346 126 0.020
Mouse
histone modification GO:0016570 159 0.020
regulation of protein localization GO:0032880 231 0.020
negative regulation of mitotic cell cycle GO:0045930 58 0.020
nucleobase containing small molecule metabolic process GO:0055086 352 0.020
regulation of cytoskeleton organization GO:0051493 122 0.019
cellular response to organonitrogen compound GO:0071417 145 0.019
engulfment of apoptotic cell GO:0043652 3 0.019
cell cycle checkpoint GO:0000075 47 0.019
positive regulation of organelle organization GO:0010638 128 0.019
regulation of transferase activity GO:0051338 263 0.019
lipid biosynthetic process GO:0008610 179 0.019
anatomical structure homeostasis GO:0060249 145 0.019
histone lysine methylation GO:0034968 50 0.019
response to light stimulus GO:0009416 135 0.019
regulation of chromosome organization GO:0033044 83 0.019
intracellular protein transport GO:0006886 204 0.018
posttranscriptional regulation of gene expression GO:0010608 155 0.018
regulation of histone h3 k36 methylation GO:0000414 1 0.018
maintenance of location GO:0051235 89 0.018
regulation of hormone levels GO:0010817 211 0.018
homeostasis of number of cells GO:0048872 210 0.018
protein targeting GO:0006605 143 0.018
organic hydroxy compound metabolic process GO:1901615 203 0.018
organonitrogen compound catabolic process GO:1901565 264 0.017
regulation of kinase activity GO:0043549 249 0.017
nucleoside phosphate metabolic process GO:0006753 338 0.017
regulation of cell cycle phase transition GO:1901987 77 0.017
Mouse
transmembrane transport GO:0055085 412 0.017
nucleocytoplasmic transport GO:0006913 139 0.017
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.017
cellular nitrogen compound catabolic process GO:0044270 280 0.017
dna recombination GO:0006310 92 0.017
gene silencing GO:0016458 38 0.017
negative regulation of cell proliferation GO:0008285 296 0.017
ribonucleoside metabolic process GO:0009119 245 0.017
nuclear transport GO:0051169 139 0.017
purine ribonucleotide metabolic process GO:0009150 290 0.016
protein localization to nucleus GO:0034504 121 0.016
regulation of cell activation GO:0050865 289 0.016
oocyte axis specification GO:0007309 2 0.016
nucleus organization GO:0006997 45 0.016
cellular protein catabolic process GO:0044257 155 0.016
cellularization GO:0007349 1 0.016
rna splicing GO:0008380 54 0.015
organonitrogen compound biosynthetic process GO:1901566 192 0.015
regulation of hydrolase activity GO:0051336 246 0.015
Human
negative regulation of cellular protein metabolic process GO:0032269 247 0.015
positive regulation of cellular component biogenesis GO:0044089 94 0.015
regulation of lymphocyte activation GO:0051249 240 0.015
dephosphorylation GO:0016311 129 0.015
modification dependent protein catabolic process GO:0019941 133 0.015
actin cytoskeleton organization GO:0030036 220 0.015
positive regulation of protein phosphorylation GO:0001934 242 0.015
leukocyte proliferation GO:0070661 172 0.015
protein localization to organelle GO:0033365 185 0.015
negative regulation of cellular amine metabolic process GO:0033239 1 0.015
blastocyst development GO:0001824 80 0.015
negative regulation of molecular function GO:0044092 258 0.015
Mouse
organic cyclic compound catabolic process GO:1901361 295 0.015
regulation of transcription by chromatin organization GO:0034401 0 0.015
regulation of protein maturation GO:1903317 96 0.015
negative regulation of cell cycle phase transition GO:1901988 48 0.015
ribonucleoside catabolic process GO:0042454 206 0.015
cellular homeostasis GO:0019725 240 0.014
protein import GO:0017038 101 0.014
cell type specific apoptotic process GO:0097285 268 0.014
skeletal system development GO:0001501 356 0.014
sensory perception GO:0007600 245 0.014
ubiquitin dependent protein catabolic process GO:0006511 129 0.014
cytokine production GO:0001816 319 0.014
rna interference GO:0016246 2 0.014
negative regulation of cell development GO:0010721 169 0.014
t cell activation GO:0042110 289 0.014
ribose phosphate metabolic process GO:0019693 291 0.014
chromatin silencing at rdna GO:0000183 3 0.014
small molecule biosynthetic process GO:0044283 132 0.014
meiotic cell cycle process GO:1903046 77 0.014
muscle tissue development GO:0060537 308 0.014
organophosphate catabolic process GO:0046434 232 0.014
negative regulation of protein modification process GO:0031400 163 0.014
stem cell differentiation GO:0048863 268 0.014
ribonucleotide metabolic process GO:0009259 291 0.014
negative regulation of dna replication GO:0008156 4 0.014
regulation of chromatin silencing GO:0031935 2 0.014
organelle assembly GO:0070925 177 0.014
mrna metabolic process GO:0016071 84 0.014
regulation of neuron differentiation GO:0045664 281 0.013
carbohydrate metabolic process GO:0005975 230 0.013
developmental maturation GO:0021700 193 0.013
regulation of histone methylation GO:0031060 30 0.013
positive regulation of hydrolase activity GO:0051345 148 0.013
Human
ossification GO:0001503 216 0.013
lymphocyte differentiation GO:0030098 242 0.013
cell adhesion GO:0007155 329 0.013
nucleotide metabolic process GO:0009117 332 0.013
camera type eye development GO:0043010 266 0.013
fertilization GO:0009566 127 0.013
regulation of proteasomal protein catabolic process GO:0061136 46 0.013
regulation of multi organism process GO:0043900 111 0.013
lymphocyte proliferation GO:0046651 164 0.013
single organism nuclear import GO:1902593 95 0.013
compound eye development GO:0048749 1 0.013
nucleoside catabolic process GO:0009164 206 0.013
purine nucleotide metabolic process GO:0006163 302 0.013
protein ubiquitination GO:0016567 171 0.013
glycosyl compound metabolic process GO:1901657 246 0.013
regulation of nuclear division GO:0051783 56 0.013
ribonucleoside triphosphate metabolic process GO:0009199 220 0.013
multicellular organismal signaling GO:0035637 91 0.013
regulation of protein processing GO:0070613 96 0.013
striated muscle tissue development GO:0014706 293 0.013
cilium morphogenesis GO:0060271 102 0.013
oocyte construction GO:0007308 2 0.013
double strand break repair GO:0006302 48 0.013
skin development GO:0043588 220 0.013
microtubule nucleation GO:0007020 2 0.013
intrinsic apoptotic signaling pathway GO:0097193 132 0.013
purine containing compound metabolic process GO:0072521 311 0.013
digestive system development GO:0055123 200 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.012
mitotic nuclear division GO:0007067 48 0.012
protein processing GO:0016485 163 0.012
negative regulation of proteolysis GO:0045861 74 0.012
cation transmembrane transport GO:0098655 266 0.012
regulation of cell motility GO:2000145 236 0.012
regulation of secretion by cell GO:1903530 249 0.012
regulation of protein complex assembly GO:0043254 83 0.012
stem cell development GO:0048864 219 0.012
purine nucleoside catabolic process GO:0006152 205 0.012
purine nucleotide catabolic process GO:0006195 211 0.012
regulation of intracellular transport GO:0032386 159 0.012
cellular component assembly involved in morphogenesis GO:0010927 139 0.012
regulation of protein kinase activity GO:0045859 232 0.012
protein import into nucleus GO:0006606 95 0.012
multicellular organismal homeostasis GO:0048871 164 0.012
cellular response to hormone stimulus GO:0032870 150 0.012
regulation of protein stability GO:0031647 52 0.012
nucleoside triphosphate metabolic process GO:0009141 230 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.012
locomotory behavior GO:0007626 195 0.012
cellular response to cytokine stimulus GO:0071345 189 0.012
regulation of establishment of protein localization GO:0070201 181 0.012
regulation of proteolysis GO:0030162 164 0.012
production of molecular mediator of immune response GO:0002440 103 0.012
regulation of mitotic cell cycle phase transition GO:1901990 73 0.012
Mouse
sensory organ morphogenesis GO:0090596 242 0.012
nuclear import GO:0051170 95 0.012
positive regulation of nucleotide metabolic process GO:0045981 114 0.012
embryonic organ morphogenesis GO:0048562 276 0.012
positive regulation of nervous system development GO:0051962 221 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.011
spermatid differentiation GO:0048515 115 0.011
regulation of nucleoside metabolic process GO:0009118 130 0.011
rho protein signal transduction GO:0007266 32 0.011
regulation of cytokine production GO:0001817 266 0.011
intracellular mrna localization GO:0008298 4 0.011
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.011
regulation of cell migration GO:0030334 219 0.011
negative regulation of protein catabolic process GO:0042177 36 0.011
positive regulation of cell cycle process GO:0090068 61 0.011
regulation of protein transport GO:0051223 163 0.011
protein polymerization GO:0051258 57 0.011
b cell activation GO:0042113 161 0.011
purine ribonucleoside metabolic process GO:0046128 241 0.011
digestive tract development GO:0048565 190 0.011
spermatid development GO:0007286 108 0.011
lateral inhibition GO:0046331 1 0.011
divalent inorganic cation transport GO:0072511 178 0.011
regulation of nucleotide metabolic process GO:0006140 169 0.011
divalent metal ion transport GO:0070838 172 0.011
negative regulation of cellular catabolic process GO:0031330 47 0.011
purine nucleoside metabolic process GO:0042278 241 0.011
purine ribonucleotide catabolic process GO:0009154 208 0.011
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.011
female gamete generation GO:0007292 74 0.011
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.011
male meiosis i GO:0007141 16 0.011
myeloid cell differentiation GO:0030099 233 0.011
cellular chemical homeostasis GO:0055082 215 0.011
negative regulation of nervous system development GO:0051961 156 0.011
guanosine containing compound catabolic process GO:1901069 144 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.011
nucleoside phosphate catabolic process GO:1901292 222 0.011
reactive oxygen species metabolic process GO:0072593 84 0.011
leukocyte mediated immunity GO:0002443 174 0.011
alcohol metabolic process GO:0006066 116 0.011
stem cell maintenance GO:0019827 130 0.010
telomere capping GO:0016233 4 0.010
heterochromatin organization GO:0070828 4 0.010
inorganic ion transmembrane transport GO:0098660 234 0.010
regulation of cellular response to stress GO:0080135 159 0.010
Mouse
response to insulin GO:0032868 100 0.010
skeletal muscle organ development GO:0060538 163 0.010
cell fate commitment GO:0045165 210 0.010
regulation of purine nucleotide metabolic process GO:1900542 169 0.010
negative regulation of chromatin silencing GO:0031936 1 0.010
lymphocyte mediated immunity GO:0002449 139 0.010
establishment or maintenance of cell polarity GO:0007163 86 0.010
hematopoietic progenitor cell differentiation GO:0002244 143 0.010
regulation of cytoplasmic transport GO:1903649 112 0.010
carbohydrate derivative biosynthetic process GO:1901137 183 0.010
negative regulation of protein maturation GO:1903318 79 0.010
regulation of anatomical structure size GO:0090066 178 0.010
neural tube development GO:0021915 160 0.010
mrna transport GO:0051028 13 0.010
nuclear export GO:0051168 34 0.010
negative regulation of phosphate metabolic process GO:0045936 184 0.010
forebrain development GO:0030900 302 0.010
angiogenesis GO:0001525 201 0.010
endocytosis GO:0006897 168 0.010
cell maturation GO:0048469 127 0.010
regulation of chromatin modification GO:1903308 57 0.010
positive regulation of cell cycle GO:0045787 92 0.010
cellular lipid metabolic process GO:0044255 323 0.010
male sex differentiation GO:0046661 109 0.010

Senp1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.030
disease of cellular proliferation DOID:14566 0 0.030
disease of anatomical entity DOID:7 0 0.030
nervous system disease DOID:863 0 0.030
organ system cancer DOID:0050686 0 0.026
sensory system disease DOID:0050155 0 0.018
retinal disease DOID:5679 0 0.018
retinal degeneration DOID:8466 0 0.018
eye and adnexa disease DOID:1492 0 0.018
eye disease DOID:5614 0 0.018
central nervous system disease DOID:331 0 0.016
immune system disease DOID:2914 0 0.015
hematopoietic system disease DOID:74 0 0.015
physical disorder DOID:0080015 0 0.010