Mus musculus

105 known processes

Senp1

SUMO1/sentrin specific peptidase 1

(Aliases: D15Ertd528e,2310046A20Rik,E330036L07Rik,MGC27975)

Senp1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cell cycle process GO:0010564 160 0.083
Mouse
organelle fission GO:0048285 170 0.081
cellular amino acid metabolic process GO:0006520 103 0.080
cellular ketone metabolic process GO:0042180 84 0.072
cellular response to dna damage stimulus GO:0006974 207 0.070
Mouse
mitotic cell cycle process GO:1903047 159 0.067
Mouse
regulation of cell cycle GO:0051726 281 0.063
Mouse
mitotic cell cycle GO:0000278 195 0.062
Mouse
microtubule based process GO:0007017 236 0.061
amine metabolic process GO:0009308 45 0.059
regulation of cellular amino acid metabolic process GO:0006521 5 0.059
cellular amine metabolic process GO:0044106 44 0.059
regulation of cellular amine metabolic process GO:0033238 20 0.058
regulation of cellular ketone metabolic process GO:0010565 66 0.056
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.053
nuclear division GO:0000280 158 0.052
meiotic cell cycle GO:0051321 122 0.051
dna metabolic process GO:0006259 303 0.048
Mouse
chromatin organization GO:0006325 206 0.045
regulation of organelle organization GO:0033043 289 0.042
positive regulation of cellular amine metabolic process GO:0033240 5 0.039
chromatin modification GO:0016568 187 0.038
negative regulation of cellular component organization GO:0051129 194 0.038
positive regulation of apoptotic process GO:0043065 217 0.036
Human
spermatogenesis GO:0007283 284 0.036
macromolecule catabolic process GO:0009057 281 0.035
methylation GO:0032259 134 0.034
peptidyl amino acid modification GO:0018193 336 0.032
gonad development GO:0008406 141 0.031
male gamete generation GO:0048232 285 0.031
negative regulation of organelle organization GO:0010639 90 0.031
microtubule cytoskeleton organization GO:0000226 157 0.031
dna repair GO:0006281 107 0.030
nitrogen compound transport GO:0071705 271 0.030
apoptotic signaling pathway GO:0097190 306 0.029
Human
cellular macromolecule catabolic process GO:0044265 206 0.028
meiotic nuclear division GO:0007126 115 0.028
regulation of cellular catabolic process GO:0031329 242 0.028
negative regulation of cell cycle GO:0045786 123 0.028
protein methylation GO:0006479 81 0.027
response to radiation GO:0009314 165 0.027
positive regulation of protein modification process GO:0031401 299 0.026
male meiosis GO:0007140 37 0.026
small gtpase mediated signal transduction GO:0007264 97 0.026
germ cell development GO:0007281 185 0.026
positive regulation of programmed cell death GO:0043068 218 0.025
Human
negative regulation of cell cycle process GO:0010948 69 0.025
protein maturation GO:0051604 176 0.025
membrane organization GO:0061024 245 0.024
immune effector process GO:0002252 321 0.024
regulation of apoptotic signaling pathway GO:2001233 197 0.023
regulation of cell division GO:0051302 76 0.023
protein modification by small protein conjugation GO:0032446 187 0.023
cation transport GO:0006812 399 0.023
protein alkylation GO:0008213 81 0.023
nucleoside metabolic process GO:0009116 246 0.023
development of primary sexual characteristics GO:0045137 143 0.023
protein catabolic process GO:0030163 221 0.022
cytoplasmic transport GO:0016482 234 0.022
regulation of membrane potential GO:0042391 192 0.022
regulation of cellular component biogenesis GO:0044087 181 0.021
covalent chromatin modification GO:0016569 163 0.021
negative regulation of protein metabolic process GO:0051248 282 0.021
aromatic compound catabolic process GO:0019439 286 0.021
oxidation reduction process GO:0055114 342 0.021
cellular protein complex assembly GO:0043623 116 0.021
heterocycle catabolic process GO:0046700 280 0.021
leukocyte differentiation GO:0002521 342 0.021
endomembrane system organization GO:0010256 147 0.020
ras protein signal transduction GO:0007265 77 0.020
histone methylation GO:0016571 71 0.020
cell division GO:0051301 120 0.020
rna processing GO:0006396 105 0.020
protein modification by small protein conjugation or removal GO:0070647 207 0.020
positive regulation of cell death GO:0010942 224 0.020
Human
response to organonitrogen compound GO:0010243 246 0.020
macromolecule methylation GO:0043414 120 0.020
ion transmembrane transport GO:0034220 361 0.020
regulation of mitotic cell cycle GO:0007346 126 0.020
Mouse
histone modification GO:0016570 159 0.020
regulation of protein localization GO:0032880 231 0.020
negative regulation of mitotic cell cycle GO:0045930 58 0.020
nucleobase containing small molecule metabolic process GO:0055086 352 0.020
regulation of cytoskeleton organization GO:0051493 122 0.019
cellular response to organonitrogen compound GO:0071417 145 0.019
engulfment of apoptotic cell GO:0043652 3 0.019
cell cycle checkpoint GO:0000075 47 0.019
positive regulation of organelle organization GO:0010638 128 0.019
regulation of transferase activity GO:0051338 263 0.019
lipid biosynthetic process GO:0008610 179 0.019
anatomical structure homeostasis GO:0060249 145 0.019
histone lysine methylation GO:0034968 50 0.019
response to light stimulus GO:0009416 135 0.019
regulation of chromosome organization GO:0033044 83 0.019
intracellular protein transport GO:0006886 204 0.018
posttranscriptional regulation of gene expression GO:0010608 155 0.018
regulation of histone h3 k36 methylation GO:0000414 1 0.018
maintenance of location GO:0051235 89 0.018
regulation of hormone levels GO:0010817 211 0.018
homeostasis of number of cells GO:0048872 210 0.018
protein targeting GO:0006605 143 0.018
organic hydroxy compound metabolic process GO:1901615 203 0.018
organonitrogen compound catabolic process GO:1901565 264 0.017
regulation of kinase activity GO:0043549 249 0.017
nucleoside phosphate metabolic process GO:0006753 338 0.017
regulation of cell cycle phase transition GO:1901987 77 0.017
Mouse
transmembrane transport GO:0055085 412 0.017
nucleocytoplasmic transport GO:0006913 139 0.017
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.017
cellular nitrogen compound catabolic process GO:0044270 280 0.017
dna recombination GO:0006310 92 0.017
gene silencing GO:0016458 38 0.017
negative regulation of cell proliferation GO:0008285 296 0.017
ribonucleoside metabolic process GO:0009119 245 0.017
nuclear transport GO:0051169 139 0.017
purine ribonucleotide metabolic process GO:0009150 290 0.016
protein localization to nucleus GO:0034504 121 0.016
regulation of cell activation GO:0050865 289 0.016
oocyte axis specification GO:0007309 2 0.016
nucleus organization GO:0006997 45 0.016
cellular protein catabolic process GO:0044257 155 0.016
cellularization GO:0007349 1 0.016
rna splicing GO:0008380 54 0.015
organonitrogen compound biosynthetic process GO:1901566 192 0.015
regulation of hydrolase activity GO:0051336 246 0.015
Human
negative regulation of cellular protein metabolic process GO:0032269 247 0.015
positive regulation of cellular component biogenesis GO:0044089 94 0.015
regulation of lymphocyte activation GO:0051249 240 0.015
dephosphorylation GO:0016311 129 0.015
modification dependent protein catabolic process GO:0019941 133 0.015
actin cytoskeleton organization GO:0030036 220 0.015
positive regulation of protein phosphorylation GO:0001934 242 0.015
leukocyte proliferation GO:0070661 172 0.015
protein localization to organelle GO:0033365 185 0.015
negative regulation of cellular amine metabolic process GO:0033239 1 0.015
blastocyst development GO:0001824 80 0.015
negative regulation of molecular function GO:0044092 258 0.015
Mouse
organic cyclic compound catabolic process GO:1901361 295 0.015
regulation of transcription by chromatin organization GO:0034401 0 0.015
regulation of protein maturation GO:1903317 96 0.015
negative regulation of cell cycle phase transition GO:1901988 48 0.015
ribonucleoside catabolic process GO:0042454 206 0.015
cellular homeostasis GO:0019725 240 0.014
protein import GO:0017038 101 0.014
cell type specific apoptotic process GO:0097285 268 0.014
skeletal system development GO:0001501 356 0.014
sensory perception GO:0007600 245 0.014
ubiquitin dependent protein catabolic process GO:0006511 129 0.014
cytokine production GO:0001816 319 0.014
rna interference GO:0016246 2 0.014
negative regulation of cell development GO:0010721 169 0.014
t cell activation GO:0042110 289 0.014
ribose phosphate metabolic process GO:0019693 291 0.014
chromatin silencing at rdna GO:0000183 3 0.014
small molecule biosynthetic process GO:0044283 132 0.014
meiotic cell cycle process GO:1903046 77 0.014
muscle tissue development GO:0060537 308 0.014
organophosphate catabolic process GO:0046434 232 0.014
negative regulation of protein modification process GO:0031400 163 0.014
stem cell differentiation GO:0048863 268 0.014
ribonucleotide metabolic process GO:0009259 291 0.014
negative regulation of dna replication GO:0008156 4 0.014
regulation of chromatin silencing GO:0031935 2 0.014
organelle assembly GO:0070925 177 0.014
mrna metabolic process GO:0016071 84 0.014
regulation of neuron differentiation GO:0045664 281 0.013
carbohydrate metabolic process GO:0005975 230 0.013
developmental maturation GO:0021700 193 0.013
regulation of histone methylation GO:0031060 30 0.013
positive regulation of hydrolase activity GO:0051345 148 0.013
Human
ossification GO:0001503 216 0.013
lymphocyte differentiation GO:0030098 242 0.013
cell adhesion GO:0007155 329 0.013
nucleotide metabolic process GO:0009117 332 0.013
camera type eye development GO:0043010 266 0.013
fertilization GO:0009566 127 0.013
regulation of proteasomal protein catabolic process GO:0061136 46 0.013
regulation of multi organism process GO:0043900 111 0.013
lymphocyte proliferation GO:0046651 164 0.013
single organism nuclear import GO:1902593 95 0.013
compound eye development GO:0048749 1 0.013
nucleoside catabolic process GO:0009164 206 0.013
purine nucleotide metabolic process GO:0006163 302 0.013
protein ubiquitination GO:0016567 171 0.013
glycosyl compound metabolic process GO:1901657 246 0.013
regulation of nuclear division GO:0051783 56 0.013
ribonucleoside triphosphate metabolic process GO:0009199 220 0.013
multicellular organismal signaling GO:0035637 91 0.013
regulation of protein processing GO:0070613 96 0.013
striated muscle tissue development GO:0014706 293 0.013
cilium morphogenesis GO:0060271 102 0.013
oocyte construction GO:0007308 2 0.013
double strand break repair GO:0006302 48 0.013
skin development GO:0043588 220 0.013
microtubule nucleation GO:0007020 2 0.013
intrinsic apoptotic signaling pathway GO:0097193 132 0.013
purine containing compound metabolic process GO:0072521 311 0.013
digestive system development GO:0055123 200 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.012
mitotic nuclear division GO:0007067 48 0.012
protein processing GO:0016485 163 0.012
negative regulation of proteolysis GO:0045861 74 0.012
cation transmembrane transport GO:0098655 266 0.012
regulation of cell motility GO:2000145 236 0.012
regulation of secretion by cell GO:1903530 249 0.012
regulation of protein complex assembly GO:0043254 83 0.012
stem cell development GO:0048864 219 0.012
purine nucleoside catabolic process GO:0006152 205 0.012
purine nucleotide catabolic process GO:0006195 211 0.012
regulation of intracellular transport GO:0032386 159 0.012
cellular component assembly involved in morphogenesis GO:0010927 139 0.012
regulation of protein kinase activity GO:0045859 232 0.012
protein import into nucleus GO:0006606 95 0.012
multicellular organismal homeostasis GO:0048871 164 0.012
cellular response to hormone stimulus GO:0032870 150 0.012
regulation of protein stability GO:0031647 52 0.012
nucleoside triphosphate metabolic process GO:0009141 230 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.012
locomotory behavior GO:0007626 195 0.012
cellular response to cytokine stimulus GO:0071345 189 0.012
regulation of establishment of protein localization GO:0070201 181 0.012
regulation of proteolysis GO:0030162 164 0.012
production of molecular mediator of immune response GO:0002440 103 0.012
regulation of mitotic cell cycle phase transition GO:1901990 73 0.012
Mouse
sensory organ morphogenesis GO:0090596 242 0.012
nuclear import GO:0051170 95 0.012
positive regulation of nucleotide metabolic process GO:0045981 114 0.012
embryonic organ morphogenesis GO:0048562 276 0.012
positive regulation of nervous system development GO:0051962 221 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.011
spermatid differentiation GO:0048515 115 0.011
regulation of nucleoside metabolic process GO:0009118 130 0.011
rho protein signal transduction GO:0007266 32 0.011
regulation of cytokine production GO:0001817 266 0.011
intracellular mrna localization GO:0008298 4 0.011
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.011
regulation of cell migration GO:0030334 219 0.011
negative regulation of protein catabolic process GO:0042177 36 0.011
positive regulation of cell cycle process GO:0090068 61 0.011
regulation of protein transport GO:0051223 163 0.011
protein polymerization GO:0051258 57 0.011
b cell activation GO:0042113 161 0.011
purine ribonucleoside metabolic process GO:0046128 241 0.011
digestive tract development GO:0048565 190 0.011
spermatid development GO:0007286 108 0.011
lateral inhibition GO:0046331 1 0.011
divalent inorganic cation transport GO:0072511 178 0.011
regulation of nucleotide metabolic process GO:0006140 169 0.011
divalent metal ion transport GO:0070838 172 0.011
negative regulation of cellular catabolic process GO:0031330 47 0.011
purine nucleoside metabolic process GO:0042278 241 0.011
purine ribonucleotide catabolic process GO:0009154 208 0.011
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.011
female gamete generation GO:0007292 74 0.011
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.011
male meiosis i GO:0007141 16 0.011
myeloid cell differentiation GO:0030099 233 0.011
cellular chemical homeostasis GO:0055082 215 0.011
negative regulation of nervous system development GO:0051961 156 0.011
guanosine containing compound catabolic process GO:1901069 144 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.011
nucleoside phosphate catabolic process GO:1901292 222 0.011
reactive oxygen species metabolic process GO:0072593 84 0.011
leukocyte mediated immunity GO:0002443 174 0.011
alcohol metabolic process GO:0006066 116 0.011
stem cell maintenance GO:0019827 130 0.010
telomere capping GO:0016233 4 0.010
heterochromatin organization GO:0070828 4 0.010
inorganic ion transmembrane transport GO:0098660 234 0.010
regulation of cellular response to stress GO:0080135 159 0.010
Mouse
response to insulin GO:0032868 100 0.010
skeletal muscle organ development GO:0060538 163 0.010
cell fate commitment GO:0045165 210 0.010
regulation of purine nucleotide metabolic process GO:1900542 169 0.010
negative regulation of chromatin silencing GO:0031936 1 0.010
lymphocyte mediated immunity GO:0002449 139 0.010
establishment or maintenance of cell polarity GO:0007163 86 0.010
hematopoietic progenitor cell differentiation GO:0002244 143 0.010
regulation of cytoplasmic transport GO:1903649 112 0.010
carbohydrate derivative biosynthetic process GO:1901137 183 0.010
negative regulation of protein maturation GO:1903318 79 0.010
regulation of anatomical structure size GO:0090066 178 0.010
neural tube development GO:0021915 160 0.010
mrna transport GO:0051028 13 0.010
nuclear export GO:0051168 34 0.010
negative regulation of phosphate metabolic process GO:0045936 184 0.010
forebrain development GO:0030900 302 0.010
angiogenesis GO:0001525 201 0.010
endocytosis GO:0006897 168 0.010
cell maturation GO:0048469 127 0.010
regulation of chromatin modification GO:1903308 57 0.010
positive regulation of cell cycle GO:0045787 92 0.010
cellular lipid metabolic process GO:0044255 323 0.010
male sex differentiation GO:0046661 109 0.010

Senp1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.030
cancer DOID:162 0 0.030
nervous system disease DOID:863 0 0.030
disease of anatomical entity DOID:7 0 0.030
organ system cancer DOID:0050686 0 0.026
sensory system disease DOID:0050155 0 0.018
eye and adnexa disease DOID:1492 0 0.018
retinal disease DOID:5679 0 0.018
retinal degeneration DOID:8466 0 0.018
eye disease DOID:5614 0 0.018
central nervous system disease DOID:331 0 0.016
hematopoietic system disease DOID:74 0 0.015
immune system disease DOID:2914 0 0.015
physical disorder DOID:0080015 0 0.010