Mus musculus

0 known processes

Pnkp

polynucleotide kinase 3'- phosphatase

(Aliases: PNK,1810009G08Rik)

Pnkp biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
microtubule based process GO:0007017 236 0.086
cellular amino acid metabolic process GO:0006520 103 0.081
peptidyl amino acid modification GO:0018193 336 0.072
cellular response to cytokine stimulus GO:0071345 189 0.065
t cell activation GO:0042110 289 0.060
nucleoside triphosphate metabolic process GO:0009141 230 0.057
regulation of hydrolase activity GO:0051336 246 0.057
cellular ketone metabolic process GO:0042180 84 0.056
macromolecule catabolic process GO:0009057 281 0.051
endomembrane system organization GO:0010256 147 0.049
glycosyl compound catabolic process GO:1901658 206 0.047
protein maturation GO:0051604 176 0.047
heterocycle catabolic process GO:0046700 280 0.046
organelle localization GO:0051640 179 0.045
trna wobble uridine modification GO:0002098 2 0.045
negative regulation of cellular component organization GO:0051129 194 0.044
amine metabolic process GO:0009308 45 0.043
regulation of cellular ketone metabolic process GO:0010565 66 0.043
regulation of cellular component biogenesis GO:0044087 181 0.041
positive regulation of triglyceride lipase activity GO:0061365 3 0.040
negative regulation of molecular function GO:0044092 258 0.039
microtubule cytoskeleton organization GO:0000226 157 0.039
regulation of cellular amine metabolic process GO:0033238 20 0.038
positive regulation of apoptotic process GO:0043065 217 0.037
cellular amine metabolic process GO:0044106 44 0.037
regulation of t cell proliferation GO:0042129 92 0.036
nucleobase containing small molecule metabolic process GO:0055086 352 0.036
positive regulation of programmed cell death GO:0043068 218 0.034
purine nucleoside triphosphate catabolic process GO:0009146 203 0.034
spermatogenesis GO:0007283 284 0.033
organophosphate catabolic process GO:0046434 232 0.033
histone modification GO:0016570 159 0.033
protein modification by small protein conjugation GO:0032446 187 0.033
regulation of cellular amino acid metabolic process GO:0006521 5 0.033
protein catabolic process GO:0030163 221 0.032
aromatic compound catabolic process GO:0019439 286 0.032
regulation of cell projection organization GO:0031344 206 0.032
golgi to endosome transport GO:0006895 3 0.032
positive regulation of cell death GO:0010942 224 0.032
modification dependent macromolecule catabolic process GO:0043632 133 0.031
synaptic transmission GO:0007268 329 0.031
regulation of proteolysis GO:0030162 164 0.030
iron sulfur cluster assembly GO:0016226 3 0.030
ribonucleoside metabolic process GO:0009119 245 0.030
protein ubiquitination GO:0016567 171 0.029
regulation of homeostatic process GO:0032844 182 0.029
positive regulation of transferase activity GO:0051347 167 0.029
nucleoside phosphate metabolic process GO:0006753 338 0.029
camera type eye development GO:0043010 266 0.029
endocytosis GO:0006897 168 0.028
histone threonine phosphorylation GO:0035405 1 0.028
ribose phosphate metabolic process GO:0019693 291 0.028
synapse organization GO:0050808 125 0.028
cellular response to biotic stimulus GO:0071216 92 0.028
negative regulation of protein metabolic process GO:0051248 282 0.028
divalent metal ion transport GO:0070838 172 0.027
regulation of t cell activation GO:0050863 170 0.026
regulation of organelle organization GO:0033043 289 0.026
nitrogen compound transport GO:0071705 271 0.026
purine ribonucleotide metabolic process GO:0009150 290 0.026
rna processing GO:0006396 105 0.026
defense response to virus GO:0051607 68 0.026
protein modification by small protein conjugation or removal GO:0070647 207 0.025
divalent inorganic cation transport GO:0072511 178 0.025
male gamete generation GO:0048232 285 0.025
sequestering of calcium ion GO:0051208 18 0.025
purine containing compound metabolic process GO:0072521 311 0.025
apoptotic signaling pathway GO:0097190 306 0.024
positive regulation of hydrolase activity GO:0051345 148 0.024
negative regulation of organelle organization GO:0010639 90 0.024
cellular nitrogen compound catabolic process GO:0044270 280 0.024
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.024
glycosyl compound metabolic process GO:1901657 246 0.023
membrane organization GO:0061024 245 0.023
cellular protein catabolic process GO:0044257 155 0.023
response to growth factor GO:0070848 198 0.023
regulation of cytoplasmic transport GO:1903649 112 0.023
regulation of lipoprotein lipase activity GO:0051004 4 0.023
organic cyclic compound catabolic process GO:1901361 295 0.022
cellular response to growth factor stimulus GO:0071363 197 0.022
regulation of binding GO:0051098 111 0.022
nucleotide metabolic process GO:0009117 332 0.022
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.022
glucose homeostasis GO:0042593 128 0.022
sulfur compound metabolic process GO:0006790 100 0.022
calcium ion transport GO:0006816 159 0.021
ubiquitin dependent protein catabolic process GO:0006511 129 0.021
positive regulation of protein modification process GO:0031401 299 0.021
regulation of transferase activity GO:0051338 263 0.021
glycerolipid metabolic process GO:0046486 122 0.021
regulation of feeding behavior GO:0060259 3 0.021
cell fate commitment GO:0045165 210 0.020
posttranscriptional regulation of gene expression GO:0010608 155 0.020
negative regulation of cytoskeleton organization GO:0051494 36 0.020
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.019
carbohydrate derivative catabolic process GO:1901136 231 0.019
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.019
regulation of endocytosis GO:0030100 69 0.019
extrinsic apoptotic signaling pathway GO:0097191 126 0.019
cellular macromolecule catabolic process GO:0044265 206 0.019
regulation of apoptotic signaling pathway GO:2001233 197 0.019
multicellular organism growth GO:0035264 161 0.019
regulation of cell activation GO:0050865 289 0.019
translation GO:0006412 93 0.019
cellular response to lipopolysaccharide GO:0071222 77 0.019
organonitrogen compound catabolic process GO:1901565 264 0.019
lymphocyte proliferation GO:0046651 164 0.019
regulation of peptidase activity GO:0052547 96 0.019
sequestering of metal ion GO:0051238 19 0.018
vesicle localization GO:0051648 86 0.018
mapk cascade GO:0000165 281 0.018
regulation of secretion by cell GO:1903530 249 0.018
metal ion homeostasis GO:0055065 189 0.018
positive regulation of protein kinase activity GO:0045860 144 0.018
positive regulation of cellular component biogenesis GO:0044089 94 0.018
leukocyte proliferation GO:0070661 172 0.018
regulation of lymphocyte activation GO:0051249 240 0.018
guanosine containing compound metabolic process GO:1901068 144 0.018
modification dependent protein catabolic process GO:0019941 133 0.018
regulation of kinase activity GO:0043549 249 0.018
cation transport GO:0006812 399 0.017
purine nucleoside metabolic process GO:0042278 241 0.017
regulation of vesicle mediated transport GO:0060627 139 0.017
maintenance of location GO:0051235 89 0.017
purine ribonucleotide catabolic process GO:0009154 208 0.017
nucleoside metabolic process GO:0009116 246 0.017
mitotic cell cycle GO:0000278 195 0.017
lymphocyte differentiation GO:0030098 242 0.017
negative regulation of cytokine production GO:0001818 84 0.017
rna interference GO:0016246 2 0.017
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.016
protein targeting GO:0006605 143 0.016
intracellular protein transport GO:0006886 204 0.016
cellular response to dna damage stimulus GO:0006974 207 0.016
organelle fission GO:0048285 170 0.016
regulation of multi organism process GO:0043900 111 0.016
feeding behavior GO:0007631 62 0.016
g protein coupled receptor signaling pathway GO:0007186 243 0.016
cytoplasmic transport GO:0016482 234 0.016
regulation of neuron projection development GO:0010975 169 0.016
peptidyl tyrosine phosphorylation GO:0018108 143 0.016
regulation of mapk cascade GO:0043408 248 0.016
protein processing GO:0016485 163 0.016
metallo sulfur cluster assembly GO:0031163 3 0.016
cell division GO:0051301 120 0.016
cellular response to molecule of bacterial origin GO:0071219 83 0.016
dephosphorylation GO:0016311 129 0.016
purine nucleotide metabolic process GO:0006163 302 0.016
response to molecule of bacterial origin GO:0002237 143 0.015
regulation of cell cycle GO:0051726 281 0.015
myosin filament organization GO:0031033 3 0.015
ribonucleotide metabolic process GO:0009259 291 0.015
regulation of plasma lipoprotein particle levels GO:0097006 23 0.015
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 3 0.015
cholesterol storage GO:0010878 4 0.015
regulation of pancreatic juice secretion GO:0090186 4 0.015
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.015
regulation of ion transport GO:0043269 215 0.015
nucleoside phosphate catabolic process GO:1901292 222 0.015
positive regulation of kinase activity GO:0033674 155 0.015
mitotic cell cycle process GO:1903047 159 0.015
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.015
organelle assembly GO:0070925 177 0.015
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.014
neuron death GO:0070997 154 0.014
gland development GO:0048732 330 0.014
cell type specific apoptotic process GO:0097285 268 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.014
regulation of cytokine production GO:0001817 266 0.014
nucleotide catabolic process GO:0009166 217 0.014
cilium assembly GO:0042384 81 0.014
meiotic nuclear division GO:0007126 115 0.014
mitochondrion organization GO:0007005 134 0.014
positive regulation of peptide hormone secretion GO:0090277 31 0.014
carbohydrate catabolic process GO:0016052 32 0.014
mrna metabolic process GO:0016071 84 0.014
regulation of lymphocyte proliferation GO:0050670 117 0.014
negative regulation of cellular amine metabolic process GO:0033239 1 0.014
t cell proliferation GO:0042098 120 0.014
neural precursor cell proliferation GO:0061351 121 0.014
cellular lipid metabolic process GO:0044255 323 0.014
proteasomal protein catabolic process GO:0010498 98 0.014
negative regulation of proteolysis GO:0045861 74 0.013
positive regulation of cell activation GO:0050867 158 0.013
cilium morphogenesis GO:0060271 102 0.013
negative regulation of intracellular signal transduction GO:1902532 167 0.013
lateral inhibition GO:0046331 1 0.013
peptide secretion GO:0002790 114 0.013
positive regulation of leukocyte proliferation GO:0070665 73 0.013
immune effector process GO:0002252 321 0.013
cytokine production GO:0001816 319 0.013
regulation of hormone levels GO:0010817 211 0.013
negative regulation of nervous system development GO:0051961 156 0.013
regulation of establishment of protein localization GO:0070201 181 0.013
regulation of leukocyte proliferation GO:0070663 121 0.013
cellular chemical homeostasis GO:0055082 215 0.013
negative regulation of cell activation GO:0050866 111 0.013
positive regulation of lymphocyte activation GO:0051251 140 0.013
regulation of protein kinase activity GO:0045859 232 0.013
cellular ion homeostasis GO:0006873 165 0.013
nucleoside catabolic process GO:0009164 206 0.013
multi multicellular organism process GO:0044706 109 0.013
spermatid development GO:0007286 108 0.012
nucleoside triphosphate catabolic process GO:0009143 205 0.012
ribonucleoside triphosphate metabolic process GO:0009199 220 0.012
purine ribonucleoside catabolic process GO:0046130 205 0.012
positive regulation of proteolysis GO:0045862 85 0.012
meiotic cell cycle process GO:1903046 77 0.012
chromatin organization GO:0006325 206 0.012
cellular metal ion homeostasis GO:0006875 151 0.012
carbohydrate homeostasis GO:0033500 128 0.012
rna splicing GO:0008380 54 0.012
negative regulation of phosphorylation GO:0042326 166 0.012
response to inorganic substance GO:0010035 96 0.012
protein polymerization GO:0051258 57 0.012
trna wobble base modification GO:0002097 2 0.012
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.012
regulation of cytoskeleton organization GO:0051493 122 0.012
positive regulation of cellular amine metabolic process GO:0033240 5 0.012
anatomical structure homeostasis GO:0060249 145 0.012
amide transport GO:0042886 138 0.012
nucleocytoplasmic transport GO:0006913 139 0.012
tissue homeostasis GO:0001894 115 0.012
regulation of microtubule based process GO:0032886 52 0.012
purine containing compound catabolic process GO:0072523 213 0.012
cellular response to lipid GO:0071396 145 0.012
negative regulation of cellular protein metabolic process GO:0032269 247 0.012
compound eye development GO:0048749 1 0.012
peptidyl threonine phosphorylation GO:0018107 31 0.012
spermatid differentiation GO:0048515 115 0.012
ribonucleoside catabolic process GO:0042454 206 0.012
negative regulation of protein modification process GO:0031400 163 0.012
asymmetric stem cell division GO:0098722 3 0.012
positive regulation of protein phosphorylation GO:0001934 242 0.012
skin development GO:0043588 220 0.012
regulation of inflammatory response GO:0050727 147 0.012
purine nucleoside triphosphate metabolic process GO:0009144 226 0.012
cellular homeostasis GO:0019725 240 0.011
cytokinetic process GO:0032506 2 0.011
purine ribonucleoside metabolic process GO:0046128 241 0.011
regulation of cellular component size GO:0032535 121 0.011
negative regulation of protein complex disassembly GO:0043242 22 0.011
response to lipopolysaccharide GO:0032496 128 0.011
positive regulation of cell adhesion GO:0045785 80 0.011
protein localization to membrane GO:0072657 108 0.011
positive regulation of fatty acid biosynthetic process GO:0045723 3 0.011
positive regulation of homeostatic process GO:0032846 64 0.011
leukocyte differentiation GO:0002521 342 0.011
carbohydrate metabolic process GO:0005975 230 0.011
negative regulation of neuron death GO:1901215 98 0.011
meiotic cell cycle GO:0051321 122 0.011
negative regulation of endocytosis GO:0045806 12 0.011
regulation of metal ion transport GO:0010959 106 0.011
hematopoietic progenitor cell differentiation GO:0002244 143 0.011
positive regulation of lipoprotein lipase activity GO:0051006 3 0.011
regulation of cell cycle process GO:0010564 160 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.011
negative regulation of immune system process GO:0002683 209 0.011
regulation of cell motility GO:2000145 236 0.011
purine nucleoside catabolic process GO:0006152 205 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.011
regulation of lymphocyte differentiation GO:0045619 107 0.011
angiogenesis GO:0001525 201 0.010
epithelial cell proliferation GO:0050673 174 0.010
response to organonitrogen compound GO:0010243 246 0.010
blood vessel morphogenesis GO:0048514 285 0.010
regulation of protein maturation GO:1903317 96 0.010
regulation of vacuole organization GO:0044088 4 0.010
regulation of microtubule cytoskeleton organization GO:0070507 37 0.010
regulation of sterol transport GO:0032371 17 0.010
negative regulation of macrophage activation GO:0043031 2 0.010
regulation of protein transport GO:0051223 163 0.010
peptidyl tyrosine modification GO:0018212 145 0.010
organic hydroxy compound metabolic process GO:1901615 203 0.010
positive regulation of mapk cascade GO:0043410 170 0.010
ribonucleotide catabolic process GO:0009261 208 0.010
regulation of secretion GO:0051046 274 0.010
negative regulation of protein phosphorylation GO:0001933 126 0.010
asymmetric neuroblast division GO:0055059 1 0.010
nuclear division GO:0000280 158 0.010

Pnkp disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.018
disease of anatomical entity DOID:7 0 0.018
hematopoietic system disease DOID:74 0 0.017
musculoskeletal system disease DOID:17 0 0.012
disease of metabolism DOID:0014667 0 0.010
inherited metabolic disorder DOID:655 0 0.010