Mus musculus

41 known processes

Nthl1

nth (endonuclease III)-like 1 (E.coli)

(Aliases: Nth1,Octs3)

Nthl1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
heterocycle catabolic process GO:0046700 280 0.083
aromatic compound catabolic process GO:0019439 286 0.069
dna metabolic process GO:0006259 303 0.067
lymphocyte differentiation GO:0030098 242 0.059
cellular amino acid metabolic process GO:0006520 103 0.059
nucleobase containing small molecule metabolic process GO:0055086 352 0.056
cellular amine metabolic process GO:0044106 44 0.052
nucleoside phosphate metabolic process GO:0006753 338 0.049
negative regulation of immune system process GO:0002683 209 0.048
nucleotide metabolic process GO:0009117 332 0.045
regulation of cellular ketone metabolic process GO:0010565 66 0.045
leukocyte differentiation GO:0002521 342 0.042
microtubule based process GO:0007017 236 0.042
ribose phosphate metabolic process GO:0019693 291 0.041
b cell activation GO:0042113 161 0.041
regulation of multi organism process GO:0043900 111 0.040
mapk cascade GO:0000165 281 0.040
amine metabolic process GO:0009308 45 0.040
spermatogenesis GO:0007283 284 0.040
positive regulation of nervous system development GO:0051962 221 0.039
regulation of transferase activity GO:0051338 263 0.039
ribonucleotide metabolic process GO:0009259 291 0.039
cell division GO:0051301 120 0.039
digestive system development GO:0055123 200 0.038
cellular macromolecule catabolic process GO:0044265 206 0.038
macromolecule catabolic process GO:0009057 281 0.037
camera type eye development GO:0043010 266 0.037
cellular ketone metabolic process GO:0042180 84 0.037
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.037
small molecule biosynthetic process GO:0044283 132 0.037
nucleoside phosphate catabolic process GO:1901292 222 0.037
regulation of cellular amine metabolic process GO:0033238 20 0.036
meiotic nuclear division GO:0007126 115 0.034
glycosyl compound metabolic process GO:1901657 246 0.034
germ cell development GO:0007281 185 0.034
regulation of organelle organization GO:0033043 289 0.034
purine nucleotide metabolic process GO:0006163 302 0.034
purine nucleotide catabolic process GO:0006195 211 0.034
purine ribonucleoside metabolic process GO:0046128 241 0.033
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.033
regulation of cellular amino acid metabolic process GO:0006521 5 0.033
nucleoside metabolic process GO:0009116 246 0.032
regulation of kinase activity GO:0043549 249 0.032
gastrulation GO:0007369 116 0.032
regionalization GO:0003002 337 0.032
negative regulation of cell development GO:0010721 169 0.031
organic cyclic compound catabolic process GO:1901361 295 0.031
immune effector process GO:0002252 321 0.031
purine containing compound metabolic process GO:0072521 311 0.031
nucleoside triphosphate catabolic process GO:0009143 205 0.030
chemotaxis GO:0006935 247 0.030
cellular nitrogen compound catabolic process GO:0044270 280 0.030
nuclear division GO:0000280 158 0.030
regulation of protein kinase activity GO:0045859 232 0.030
regulation of neuron differentiation GO:0045664 281 0.030
purine nucleoside metabolic process GO:0042278 241 0.029
cellular lipid metabolic process GO:0044255 323 0.029
purine ribonucleoside catabolic process GO:0046130 205 0.029
respiratory tube development GO:0030323 167 0.029
organophosphate catabolic process GO:0046434 232 0.029
cell activation involved in immune response GO:0002263 126 0.028
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.028
skeletal system development GO:0001501 356 0.028
positive regulation of cellular amine metabolic process GO:0033240 5 0.027
regulation of cell activation GO:0050865 289 0.027
endocytosis GO:0006897 168 0.027
cell fate commitment GO:0045165 210 0.027
embryonic organ morphogenesis GO:0048562 276 0.027
meiotic cell cycle GO:0051321 122 0.027
digestive tract development GO:0048565 190 0.027
regulation of cell projection organization GO:0031344 206 0.026
regulation of mapk cascade GO:0043408 248 0.026
epithelial tube morphogenesis GO:0060562 303 0.026
ribonucleoside metabolic process GO:0009119 245 0.026
organelle assembly GO:0070925 177 0.026
transmembrane transport GO:0055085 412 0.026
purine ribonucleotide catabolic process GO:0009154 208 0.026
negative regulation of kinase activity GO:0033673 81 0.025
organophosphate biosynthetic process GO:0090407 122 0.025
rho protein signal transduction GO:0007266 32 0.025
gland development GO:0048732 330 0.025
forebrain development GO:0030900 302 0.025
skeletal system morphogenesis GO:0048705 203 0.024
purine containing compound catabolic process GO:0072523 213 0.024
purine nucleoside triphosphate metabolic process GO:0009144 226 0.023
male gamete generation GO:0048232 285 0.023
negative regulation of cellular protein metabolic process GO:0032269 247 0.023
regulation of protein localization GO:0032880 231 0.023
regulation of lymphocyte activation GO:0051249 240 0.023
purine nucleoside catabolic process GO:0006152 205 0.023
muscle tissue development GO:0060537 308 0.023
organonitrogen compound catabolic process GO:1901565 264 0.023
purine ribonucleotide metabolic process GO:0009150 290 0.022
sensory perception GO:0007600 245 0.022
leukocyte activation involved in immune response GO:0002366 126 0.022
organelle fission GO:0048285 170 0.022
glycosyl compound catabolic process GO:1901658 206 0.022
stem cell differentiation GO:0048863 268 0.022
bone development GO:0060348 120 0.022
regulation of cell cycle GO:0051726 281 0.022
positive regulation of mapk cascade GO:0043410 170 0.021
cellular homeostasis GO:0019725 240 0.021
respiratory system development GO:0060541 190 0.021
mitotic cell cycle GO:0000278 195 0.021
carbohydrate derivative catabolic process GO:1901136 231 0.021
asymmetric stem cell division GO:0098722 3 0.021
organelle localization GO:0051640 179 0.021
cilium morphogenesis GO:0060271 102 0.021
ion transmembrane transport GO:0034220 361 0.021
locomotory behavior GO:0007626 195 0.021
negative regulation of phosphate metabolic process GO:0045936 184 0.021
ribonucleotide catabolic process GO:0009261 208 0.021
cellular component assembly involved in morphogenesis GO:0010927 139 0.021
guanosine containing compound catabolic process GO:1901069 144 0.021
nucleoside triphosphate metabolic process GO:0009141 230 0.021
positive regulation of cell development GO:0010720 237 0.021
negative regulation of cellular component organization GO:0051129 194 0.020
ribonucleoside triphosphate metabolic process GO:0009199 220 0.020
apoptotic signaling pathway GO:0097190 306 0.020
lung development GO:0030324 164 0.020
interleukin 8 production GO:0032637 4 0.020
embryonic appendage morphogenesis GO:0035113 126 0.020
nitrogen compound transport GO:0071705 271 0.020
gtp catabolic process GO:0006184 143 0.020
blood vessel morphogenesis GO:0048514 285 0.020
oxidation reduction process GO:0055114 342 0.020
ossification GO:0001503 216 0.020
regulation of asymmetric cell division GO:0009786 4 0.020
regulation of membrane potential GO:0042391 192 0.020
striated muscle tissue development GO:0014706 293 0.020
carbohydrate derivative biosynthetic process GO:1901137 183 0.019
connective tissue development GO:0061448 179 0.019
negative regulation of phosphorus metabolic process GO:0010563 184 0.019
positive regulation of protein modification process GO:0031401 299 0.019
positive regulation of protein phosphorylation GO:0001934 242 0.019
sensory organ morphogenesis GO:0090596 242 0.019
t cell activation GO:0042110 289 0.019
oocyte construction GO:0007308 2 0.019
protein catabolic process GO:0030163 221 0.019
negative regulation of molecular function GO:0044092 258 0.019
regulation of cell cycle process GO:0010564 160 0.019
digestive tract morphogenesis GO:0048546 147 0.019
developmental maturation GO:0021700 193 0.019
organic hydroxy compound metabolic process GO:1901615 203 0.019
dna catabolic process endonucleolytic GO:0000737 15 0.019
axonogenesis GO:0007409 274 0.019
positive regulation of transferase activity GO:0051347 167 0.019
regulation of interleukin 8 production GO:0032677 3 0.019
regulation of hydrolase activity GO:0051336 246 0.019
hematopoietic progenitor cell differentiation GO:0002244 143 0.019
cytoplasmic transport GO:0016482 234 0.019
positive regulation of neuron differentiation GO:0045666 141 0.019
lymphocyte proliferation GO:0046651 164 0.019
regulation of cellular component biogenesis GO:0044087 181 0.019
ameboidal type cell migration GO:0001667 128 0.019
cellular response to dna damage stimulus GO:0006974 207 0.018
transmission of nerve impulse GO:0019226 76 0.018
posttranscriptional regulation of gene expression GO:0010608 155 0.018
t cell differentiation GO:0030217 174 0.018
innate immune response GO:0045087 157 0.018
mitotic cell cycle process GO:1903047 159 0.018
muscle cell differentiation GO:0042692 261 0.018
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.018
purine nucleoside triphosphate catabolic process GO:0009146 203 0.018
protein modification by small protein conjugation or removal GO:0070647 207 0.018
cell maturation GO:0048469 127 0.018
morphogenesis of a branching epithelium GO:0061138 193 0.018
ribonucleoside catabolic process GO:0042454 206 0.018
lipid localization GO:0010876 126 0.018
androgen biosynthetic process GO:0006702 4 0.018
wound healing GO:0042060 157 0.018
cellular response to cytokine stimulus GO:0071345 189 0.018
fat cell differentiation GO:0045444 160 0.018
wnt signaling pathway GO:0016055 188 0.018
negative regulation of protein modification process GO:0031400 163 0.017
regulation of apoptotic signaling pathway GO:2001233 197 0.017
morphogenesis of embryonic epithelium GO:0016331 159 0.017
alpha amino acid metabolic process GO:1901605 59 0.017
positive regulation of interleukin 8 production GO:0032757 2 0.017
nucleoside catabolic process GO:0009164 206 0.017
embryonic limb morphogenesis GO:0030326 126 0.017
regulation of establishment of protein localization GO:0070201 181 0.017
regulation of secretion by cell GO:1903530 249 0.017
regulation of defense response GO:0031347 233 0.017
cytokine production GO:0001816 319 0.017
nucleotide catabolic process GO:0009166 217 0.017
kidney development GO:0001822 213 0.017
myeloid cell differentiation GO:0030099 233 0.017
positive regulation of organelle organization GO:0010638 128 0.017
regulation of purine nucleotide metabolic process GO:1900542 169 0.017
skeletal muscle organ development GO:0060538 163 0.017
ear development GO:0043583 200 0.017
homeostasis of number of cells GO:0048872 210 0.017
regulation of intracellular transport GO:0032386 159 0.017
regulation of cell division GO:0051302 76 0.017
oocyte axis specification GO:0007309 2 0.017
cartilage development GO:0051216 140 0.017
cellular response to biotic stimulus GO:0071216 92 0.017
regulation of cellular component size GO:0032535 121 0.017
central nervous system neuron differentiation GO:0021953 162 0.017
regulation of secretion GO:0051046 274 0.017
appendage development GO:0048736 166 0.016
lateral inhibition GO:0046331 1 0.016
regulation of embryonic development GO:0045995 71 0.016
guanosine containing compound metabolic process GO:1901068 144 0.016
positive regulation of apoptotic process GO:0043065 217 0.016
appendage morphogenesis GO:0035107 149 0.016
positive regulation of kinase activity GO:0033674 155 0.016
membrane organization GO:0061024 245 0.016
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.016
positive regulation of lymphocyte activation GO:0051251 140 0.016
negative regulation of nervous system development GO:0051961 156 0.016
ras protein signal transduction GO:0007265 77 0.016
tube formation GO:0035148 140 0.015
cation transmembrane transport GO:0098655 266 0.015
protein localization to organelle GO:0033365 185 0.015
positive regulation of cell death GO:0010942 224 0.015
regulation of nucleotide metabolic process GO:0006140 169 0.015
fertilization GO:0009566 127 0.015
positive regulation of programmed cell death GO:0043068 218 0.015
regulation of neuron projection development GO:0010975 169 0.015
cognition GO:0050890 149 0.015
negative regulation of protein metabolic process GO:0051248 282 0.015
regulation of anatomical structure size GO:0090066 178 0.015
negative regulation of intracellular signal transduction GO:1902532 167 0.015
angiogenesis GO:0001525 201 0.015
maintenance of cell number GO:0098727 3 0.015
leukocyte proliferation GO:0070661 172 0.015
reactive oxygen species metabolic process GO:0072593 84 0.015
metal ion homeostasis GO:0055065 189 0.015
interleukin 8 secretion GO:0072606 3 0.015
negative regulation of cell cycle GO:0045786 123 0.015
regulation of mitotic cell cycle GO:0007346 126 0.015
morphogenesis of a branching structure GO:0001763 203 0.015
telencephalon development GO:0021537 186 0.015
asymmetric neuroblast division GO:0055059 1 0.015
neuron migration GO:0001764 122 0.014
regulation of cellular response to stress GO:0080135 159 0.014
negative regulation of protein phosphorylation GO:0001933 126 0.014
gtp metabolic process GO:0046039 144 0.014
cellular chemical homeostasis GO:0055082 215 0.014
positive regulation of hydrolase activity GO:0051345 148 0.014
microtubule cytoskeleton organization GO:0000226 157 0.014
regulation of proteolysis GO:0030162 164 0.014
small gtpase mediated signal transduction GO:0007264 97 0.014
organonitrogen compound biosynthetic process GO:1901566 192 0.014
rna processing GO:0006396 105 0.014
positive regulation of cytokine production GO:0001819 174 0.014
response to organonitrogen compound GO:0010243 246 0.014
regulation of cytokine production GO:0001817 266 0.014
response to inorganic substance GO:0010035 96 0.014
multicellular organismal signaling GO:0035637 91 0.014
leukocyte migration GO:0050900 124 0.014
peptidyl amino acid modification GO:0018193 336 0.014
fatty acid metabolic process GO:0006631 121 0.014
lymphocyte activation involved in immune response GO:0002285 93 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.014
retina development in camera type eye GO:0060041 119 0.014
negative regulation of cell proliferation GO:0008285 296 0.014
regulation of wnt signaling pathway GO:0030111 123 0.014
ribonucleoside triphosphate catabolic process GO:0009203 199 0.014
regulation of interleukin 8 secretion GO:2000482 2 0.014
protein localization to nucleus GO:0034504 121 0.014
stem cell proliferation GO:0072089 117 0.014
g protein coupled receptor signaling pathway GO:0007186 243 0.014
negative regulation of neuron differentiation GO:0045665 101 0.014
cation transport GO:0006812 399 0.013
placenta development GO:0001890 140 0.013
cellular metal ion homeostasis GO:0006875 151 0.013
cell adhesion GO:0007155 329 0.013
bundle of his development GO:0003166 4 0.013
cellular ion homeostasis GO:0006873 165 0.013
negative regulation of growth GO:0045926 99 0.013
pallium development GO:0021543 120 0.013
muscle system process GO:0003012 141 0.013
maternal determination of anterior posterior axis embryo GO:0008358 2 0.013
negative regulation of cell activation GO:0050866 111 0.013
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.013
cellular divalent inorganic cation homeostasis GO:0072503 127 0.013
positive regulation of nucleotide metabolic process GO:0045981 114 0.013
inorganic ion transmembrane transport GO:0098660 234 0.013
establishment of planar polarity GO:0001736 28 0.013
regulation of protein complex assembly GO:0043254 83 0.013
hindbrain development GO:0030902 128 0.013
cell type specific apoptotic process GO:0097285 268 0.013
b cell activation involved in immune response GO:0002312 50 0.013
cellular response to lipid GO:0071396 145 0.013
tube closure GO:0060606 91 0.013
dna repair GO:0006281 107 0.013
protein maturation GO:0051604 176 0.013
intracellular mrna localization GO:0008298 4 0.013
striated muscle cell development GO:0055002 125 0.013
positive regulation of stem cell proliferation GO:2000648 59 0.013
regulation of response to wounding GO:1903034 189 0.013
b cell proliferation GO:0042100 53 0.013
negative regulation of phosphorylation GO:0042326 166 0.013
blastocyst development GO:0001824 80 0.013
methylation GO:0032259 134 0.013
carbohydrate metabolic process GO:0005975 230 0.012
segmentation GO:0035282 93 0.012
cellular response to molecule of bacterial origin GO:0071219 83 0.012
lipid transport GO:0006869 98 0.012
maintenance of location GO:0051235 89 0.012
cellular calcium ion homeostasis GO:0006874 119 0.012
regulation of system process GO:0044057 200 0.012
positive regulation of proteolysis GO:0045862 85 0.012
neural tube development GO:0021915 160 0.012
testosterone biosynthetic process GO:0061370 2 0.012
establishment of organelle localization GO:0051656 122 0.012
midgut development GO:0007494 4 0.012
compound eye development GO:0048749 1 0.012
glycerolipid metabolic process GO:0046486 122 0.012
urogenital system development GO:0001655 261 0.012
response to acid chemical GO:0001101 111 0.012
establishment of tissue polarity GO:0007164 28 0.012
ribose phosphate biosynthetic process GO:0046390 59 0.012
limb morphogenesis GO:0035108 149 0.012
regulation of protein transport GO:0051223 163 0.012
male gonad development GO:0008584 88 0.012
positive regulation of cell cycle GO:0045787 92 0.012
epidermis development GO:0008544 187 0.012
multicellular organism growth GO:0035264 161 0.012
intrinsic apoptotic signaling pathway GO:0097193 132 0.012
modification dependent macromolecule catabolic process GO:0043632 133 0.012
alpha beta t cell differentiation GO:0046632 69 0.012
inorganic cation transmembrane transport GO:0098662 207 0.012
nucleocytoplasmic transport GO:0006913 139 0.012
regulation of t cell activation GO:0050863 170 0.012
b cell differentiation GO:0030183 78 0.012
primary neural tube formation GO:0014020 95 0.012
response to radiation GO:0009314 165 0.012
organic hydroxy compound biosynthetic process GO:1901617 77 0.012
production of molecular mediator of immune response GO:0002440 103 0.011
regulation of body fluid levels GO:0050878 162 0.011
regulation of tube size GO:0035150 57 0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.011
alcohol metabolic process GO:0006066 116 0.011
neuronal action potential GO:0019228 54 0.011
developmental growth involved in morphogenesis GO:0060560 138 0.011
ribonucleotide biosynthetic process GO:0009260 59 0.011
regulation of neuron death GO:1901214 134 0.011
cation homeostasis GO:0055080 212 0.011
protein targeting GO:0006605 143 0.011
regulation of leukocyte proliferation GO:0070663 121 0.011
monocarboxylic acid metabolic process GO:0032787 191 0.011
protein modification by small protein conjugation GO:0032446 187 0.011
regulation of protein catabolic process GO:0042176 108 0.011
multi multicellular organism process GO:0044706 109 0.011
mesenchyme development GO:0060485 152 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.011
determination of left right symmetry GO:0007368 80 0.011
regulation of nuclear division GO:0051783 56 0.011
action potential GO:0001508 78 0.011
nucleotide biosynthetic process GO:0009165 78 0.011
response to molecule of bacterial origin GO:0002237 143 0.011
cell cell junction organization GO:0045216 72 0.011
odontogenesis GO:0042476 78 0.011
sensory perception of mechanical stimulus GO:0050954 107 0.011
polarity specification of proximal distal axis GO:0010085 2 0.011
phospholipid metabolic process GO:0006644 87 0.011
morphogenesis of a polarized epithelium GO:0001738 37 0.011
embryonic placenta development GO:0001892 98 0.011
gonad development GO:0008406 141 0.011
negative regulation of transferase activity GO:0051348 85 0.011
mesendoderm development GO:0048382 3 0.011
activation of immune response GO:0002253 138 0.011
positive regulation of protein kinase activity GO:0045860 144 0.011
chromatin modification GO:0016568 187 0.011
inner ear morphogenesis GO:0042472 101 0.011
positive regulation of meiosis GO:0045836 14 0.011
circulatory system process GO:0003013 197 0.011
positive regulation of cell projection organization GO:0031346 95 0.011
calcium ion homeostasis GO:0055074 127 0.011
mesodermal cell migration GO:0008078 4 0.011
stem cell development GO:0048864 219 0.010
protein import GO:0017038 101 0.010
epiblast cell extraembryonic ectoderm cell signaling involved in anterior posterior axis specification GO:0060802 1 0.010
metanephric loop of henle development GO:0072236 4 0.010
inflammatory response GO:0006954 244 0.010
trachea cartilage morphogenesis GO:0060535 4 0.010
pole plasm assembly GO:0007315 2 0.010
nephrogenic mesenchyme development GO:0072076 3 0.010
leukocyte mediated immunity GO:0002443 174 0.010
meiotic cell cycle process GO:1903046 77 0.010
lymphocyte mediated immunity GO:0002449 139 0.010
nuclear transport GO:0051169 139 0.010
protein ubiquitination GO:0016567 171 0.010
cilium assembly GO:0042384 81 0.010
ear morphogenesis GO:0042471 118 0.010

Nthl1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.022
disease of anatomical entity DOID:7 0 0.022
disease of cellular proliferation DOID:14566 0 0.018
organ system cancer DOID:0050686 0 0.016
cancer DOID:162 0 0.016
sensory system disease DOID:0050155 0 0.016
eye and adnexa disease DOID:1492 0 0.016
musculoskeletal system disease DOID:17 0 0.011
eye disease DOID:5614 0 0.011
connective tissue disease DOID:65 0 0.010
cardiovascular system disease DOID:1287 0 0.010