Mus musculus

0 known processes

Lin28b

lin-28 homolog B (C. elegans)

(Aliases: D030047M17Rik,Lin-28.2,2810403D23Rik)

Lin28b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
mirna catabolic process GO:0010587 2 0.741
Human
gene silencing by mirna GO:0035195 10 0.536
Human
gene silencing by rna GO:0031047 19 0.130
Human
pre mirna processing GO:0031054 3 0.113
Human
organic cyclic compound catabolic process GO:1901361 295 0.112
Human
posttranscriptional gene silencing GO:0016441 10 0.112
Human
cellular nitrogen compound catabolic process GO:0044270 280 0.108
Human
heterocycle catabolic process GO:0046700 280 0.108
Human
posttranscriptional gene silencing by rna GO:0035194 10 0.105
Human
response to organic cyclic compound GO:0014070 198 0.092
Human
stem cell differentiation GO:0048863 268 0.090
multi multicellular organism process GO:0044706 109 0.081
regulation of neuron differentiation GO:0045664 281 0.080
gene silencing GO:0016458 38 0.079
Human
spermatogenesis GO:0007283 284 0.067
macromolecule catabolic process GO:0009057 281 0.067
Human
positive regulation of neuron differentiation GO:0045666 141 0.067
male gamete generation GO:0048232 285 0.066
urogenital system development GO:0001655 261 0.066
meiotic cell cycle GO:0051321 122 0.066
rna catabolic process GO:0006401 29 0.066
Human
regulation of cellular ketone metabolic process GO:0010565 66 0.065
cellular ketone metabolic process GO:0042180 84 0.064
chromatin organization GO:0006325 206 0.059
gliogenesis GO:0042063 141 0.058
response to organonitrogen compound GO:0010243 246 0.057
germ cell development GO:0007281 185 0.056
cellular macromolecule catabolic process GO:0044265 206 0.056
Human
positive regulation of cell development GO:0010720 237 0.055
translation GO:0006412 93 0.054
peptidyl amino acid modification GO:0018193 336 0.050
nuclear division GO:0000280 158 0.050
camera type eye development GO:0043010 266 0.050
rna processing GO:0006396 105 0.049
Human
regulation of cellular amino acid metabolic process GO:0006521 5 0.048
cellular amine metabolic process GO:0044106 44 0.048
cell fate commitment GO:0045165 210 0.047
organelle fission GO:0048285 170 0.047
sensory organ morphogenesis GO:0090596 242 0.046
histone modification GO:0016570 159 0.046
nucleoside phosphate metabolic process GO:0006753 338 0.045
negative regulation of nervous system development GO:0051961 156 0.045
negative regulation of cell development GO:0010721 169 0.045
purine containing compound metabolic process GO:0072521 311 0.043
regulation of cellular amine metabolic process GO:0033238 20 0.043
covalent chromatin modification GO:0016569 163 0.043
mirna metabolic process GO:0010586 10 0.042
Human
regulation of translation GO:0006417 71 0.042
mapk cascade GO:0000165 281 0.040
gonad development GO:0008406 141 0.040
kidney development GO:0001822 213 0.039
multicellular organism growth GO:0035264 161 0.038
nucleobase containing small molecule metabolic process GO:0055086 352 0.037
cellular amino acid metabolic process GO:0006520 103 0.037
positive regulation of nervous system development GO:0051962 221 0.037
placenta development GO:0001890 140 0.037
response to lipopolysaccharide GO:0032496 128 0.037
cell fate specification GO:0001708 72 0.037
renal system development GO:0072001 225 0.036
nucleotide metabolic process GO:0009117 332 0.036
ribose phosphate metabolic process GO:0019693 291 0.035
positive regulation of protein modification process GO:0031401 299 0.034
aromatic compound catabolic process GO:0019439 286 0.034
Human
purine ribonucleotide metabolic process GO:0009150 290 0.034
skeletal system development GO:0001501 356 0.034
forebrain development GO:0030900 302 0.034
gland development GO:0048732 330 0.034
transmembrane transport GO:0055085 412 0.033
endocytosis GO:0006897 168 0.033
response to dsrna GO:0043331 30 0.032
Human
development of primary sexual characteristics GO:0045137 143 0.032
apoptotic signaling pathway GO:0097190 306 0.031
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.031
regulation of organelle organization GO:0033043 289 0.031
ribonucleotide metabolic process GO:0009259 291 0.030
muscle tissue development GO:0060537 308 0.030
cytokine production GO:0001816 319 0.030
organonitrogen compound catabolic process GO:1901565 264 0.029
multicellular organismal signaling GO:0035637 91 0.029
amine metabolic process GO:0009308 45 0.029
chromatin modification GO:0016568 187 0.028
production of small rna involved in gene silencing by rna GO:0070918 6 0.028
Human
transmission of nerve impulse GO:0019226 76 0.028
ras protein signal transduction GO:0007265 77 0.028
oocyte construction GO:0007308 2 0.028
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.027
response to acid chemical GO:0001101 111 0.027
regulation of kidney development GO:0090183 40 0.027
inorganic ion transmembrane transport GO:0098660 234 0.027
negative regulation of cell proliferation GO:0008285 296 0.027
protein modification by small protein conjugation GO:0032446 187 0.027
central nervous system neuron differentiation GO:0021953 162 0.026
embryonic placenta development GO:0001892 98 0.026
regionalization GO:0003002 337 0.026
axonogenesis GO:0007409 274 0.026
protein modification by small protein conjugation or removal GO:0070647 207 0.026
cell type specific apoptotic process GO:0097285 268 0.026
positive regulation of cellular amine metabolic process GO:0033240 5 0.026
purine nucleotide metabolic process GO:0006163 302 0.025
response to molecule of bacterial origin GO:0002237 143 0.025
microtubule based process GO:0007017 236 0.025
membrane organization GO:0061024 245 0.025
ribonucleoside triphosphate metabolic process GO:0009199 220 0.025
regulation of cell cycle GO:0051726 281 0.025
oxidation reduction process GO:0055114 342 0.025
stem cell development GO:0048864 219 0.025
positive regulation of growth GO:0045927 104 0.024
purine nucleoside metabolic process GO:0042278 241 0.024
negative regulation of intracellular signal transduction GO:1902532 167 0.024
multi organism reproductive behavior GO:0044705 29 0.024
ossification GO:0001503 216 0.024
purine nucleotide catabolic process GO:0006195 211 0.024
regulation of mapk cascade GO:0043408 248 0.023
embryonic organ morphogenesis GO:0048562 276 0.023
oocyte axis specification GO:0007309 2 0.023
positive regulation of protein phosphorylation GO:0001934 242 0.023
organonitrogen compound biosynthetic process GO:1901566 192 0.023
nucleotide catabolic process GO:0009166 217 0.023
nucleoside triphosphate metabolic process GO:0009141 230 0.023
synaptic transmission GO:0007268 329 0.023
muscle cell differentiation GO:0042692 261 0.022
stem cell maintenance GO:0019827 130 0.022
cation homeostasis GO:0055080 212 0.022
organophosphate catabolic process GO:0046434 232 0.022
protein ubiquitination GO:0016567 171 0.022
protein demethylation GO:0006482 13 0.022
small gtpase mediated signal transduction GO:0007264 97 0.021
posttranscriptional regulation of gene expression GO:0010608 155 0.021
Human
ribonucleoside metabolic process GO:0009119 245 0.021
ribonucleotide catabolic process GO:0009261 208 0.021
regulation of organ morphogenesis GO:2000027 144 0.021
cellular protein complex assembly GO:0043623 116 0.021
regulation of transferase activity GO:0051338 263 0.021
cellular homeostasis GO:0019725 240 0.021
purine ribonucleoside metabolic process GO:0046128 241 0.021
glycosyl compound metabolic process GO:1901657 246 0.021
nucleoside metabolic process GO:0009116 246 0.021
purine ribonucleotide catabolic process GO:0009154 208 0.021
cation transport GO:0006812 399 0.021
regulation of membrane potential GO:0042391 192 0.021
regulation of binding GO:0051098 111 0.021
nucleoside phosphate catabolic process GO:1901292 222 0.021
regulation of purine nucleotide metabolic process GO:1900542 169 0.020
carbohydrate metabolic process GO:0005975 230 0.020
locomotory behavior GO:0007626 195 0.020
skeletal system morphogenesis GO:0048705 203 0.020
ion transmembrane transport GO:0034220 361 0.020
cytoplasmic transport GO:0016482 234 0.020
inorganic cation transmembrane transport GO:0098662 207 0.020
purine nucleoside triphosphate metabolic process GO:0009144 226 0.020
carbohydrate derivative catabolic process GO:1901136 231 0.020
striated muscle tissue development GO:0014706 293 0.020
negative regulation of glial cell differentiation GO:0045686 21 0.020
innate immune response GO:0045087 157 0.020
negative regulation of molecular function GO:0044092 258 0.020
purine containing compound catabolic process GO:0072523 213 0.020
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.019
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.019
bone development GO:0060348 120 0.019
cellular response to organonitrogen compound GO:0071417 145 0.019
regulation of cell cycle process GO:0010564 160 0.019
sensory perception GO:0007600 245 0.019
cellular chemical homeostasis GO:0055082 215 0.019
protein homotrimerization GO:0070207 4 0.019
cellular response to dsrna GO:0071359 12 0.019
Human
purine nucleoside triphosphate catabolic process GO:0009146 203 0.019
microtubule cytoskeleton organization GO:0000226 157 0.019
nucleoside catabolic process GO:0009164 206 0.019
negative regulation of cellular component organization GO:0051129 194 0.019
regulation of apoptotic signaling pathway GO:2001233 197 0.019
cellular carbohydrate metabolic process GO:0044262 119 0.019
dna metabolic process GO:0006259 303 0.018
cellular response to dna damage stimulus GO:0006974 207 0.018
retina development in camera type eye GO:0060041 119 0.018
regulation of protein localization GO:0032880 231 0.018
regulation of cytokine production GO:0001817 266 0.018
positive regulation of programmed cell death GO:0043068 218 0.018
multi organism behavior GO:0051705 62 0.018
ribonucleoside catabolic process GO:0042454 206 0.018
developmental growth involved in morphogenesis GO:0060560 138 0.018
cell division GO:0051301 120 0.017
developmental maturation GO:0021700 193 0.017
regulation of protein kinase activity GO:0045859 232 0.017
multicellular organismal homeostasis GO:0048871 164 0.017
g protein coupled receptor signaling pathway GO:0007186 243 0.017
protein targeting GO:0006605 143 0.017
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.017
male sex differentiation GO:0046661 109 0.017
purine ribonucleoside catabolic process GO:0046130 205 0.017
negative regulation of cellular protein metabolic process GO:0032269 247 0.017
glycosyl compound catabolic process GO:1901658 206 0.017
positive regulation of cell death GO:0010942 224 0.017
negative regulation of cytokine production GO:0001818 84 0.017
neuron death GO:0070997 154 0.017
regulation of ossification GO:0030278 112 0.017
regulation of protein serine threonine kinase activity GO:0071900 157 0.016
purine nucleoside catabolic process GO:0006152 205 0.016
blastocyst development GO:0001824 80 0.016
histone demethylation GO:0016577 13 0.016
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.016
intracellular protein transport GO:0006886 204 0.016
skin development GO:0043588 220 0.016
regulation of secretion GO:0051046 274 0.016
positive regulation of cellular catabolic process GO:0031331 148 0.016
cardiac muscle tissue development GO:0048738 130 0.016
regulation of cellular catabolic process GO:0031329 242 0.016
metal ion homeostasis GO:0055065 189 0.016
regulation of mitotic cell cycle GO:0007346 126 0.016
mitochondrion organization GO:0007005 134 0.016
homeostasis of number of cells GO:0048872 210 0.016
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.016
nitrogen compound transport GO:0071705 271 0.016
palate development GO:0060021 76 0.015
morphogenesis of embryonic epithelium GO:0016331 159 0.015
negative regulation of protein metabolic process GO:0051248 282 0.015
positive regulation of translation GO:0045727 19 0.015
maintenance of location GO:0051235 89 0.015
regulation of neuron apoptotic process GO:0043523 122 0.015
cation transmembrane transport GO:0098655 266 0.015
nucleocytoplasmic transport GO:0006913 139 0.015
ear development GO:0043583 200 0.015
organophosphate biosynthetic process GO:0090407 122 0.015
meiotic nuclear division GO:0007126 115 0.015
response to growth factor GO:0070848 198 0.015
endomembrane system organization GO:0010256 147 0.015
ribonucleoside triphosphate catabolic process GO:0009203 199 0.015
cellular lipid metabolic process GO:0044255 323 0.015
negative regulation of gliogenesis GO:0014014 23 0.015
positive regulation of hydrolase activity GO:0051345 148 0.015
small molecule biosynthetic process GO:0044283 132 0.015
epithelial cell proliferation GO:0050673 174 0.015
regulation of hydrolase activity GO:0051336 246 0.015
regulation of kinase activity GO:0043549 249 0.015
positive regulation of protein kinase activity GO:0045860 144 0.015
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.015
fat cell differentiation GO:0045444 160 0.015
regulation of glial cell differentiation GO:0045685 41 0.015
nucleoside triphosphate catabolic process GO:0009143 205 0.015
synapse organization GO:0050808 125 0.015
neuromuscular process GO:0050905 99 0.015
protein localization to membrane GO:0072657 108 0.015
action potential GO:0001508 78 0.015
negative regulation of cellular amine metabolic process GO:0033239 1 0.014
lymphocyte mediated immunity GO:0002449 139 0.014
lymphocyte differentiation GO:0030098 242 0.014
hematopoietic progenitor cell differentiation GO:0002244 143 0.014
neuron apoptotic process GO:0051402 142 0.014
carbohydrate homeostasis GO:0033500 128 0.014
negative regulation of phosphate metabolic process GO:0045936 184 0.014
nuclear transport GO:0051169 139 0.014
epithelial tube morphogenesis GO:0060562 303 0.014
anion transport GO:0006820 177 0.014
segmentation GO:0035282 93 0.014
circulatory system process GO:0003013 197 0.014
tube closure GO:0060606 91 0.014
tissue homeostasis GO:0001894 115 0.014
regulation of secretion by cell GO:1903530 249 0.014
demethylation GO:0070988 23 0.014
receptor mediated endocytosis GO:0006898 51 0.014
fertilization GO:0009566 127 0.014
male gonad development GO:0008584 88 0.014
leukocyte differentiation GO:0002521 342 0.014
chemotaxis GO:0006935 247 0.014
regulation of neuron death GO:1901214 134 0.014
regulation of homeostatic process GO:0032844 182 0.014
regulation of gliogenesis GO:0014013 50 0.014
mesodermal cell migration GO:0008078 4 0.014
epidermis development GO:0008544 187 0.014
negative regulation of protein modification process GO:0031400 163 0.014
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.014
organic anion transport GO:0015711 137 0.014
cellular response to hormone stimulus GO:0032870 150 0.014
regulation of cell cycle checkpoint GO:1901976 9 0.014
protein catabolic process GO:0030163 221 0.014
learning GO:0007612 98 0.014
multicellular organismal response to stress GO:0033555 62 0.014
regulation of nuclear division GO:0051783 56 0.014
reactive oxygen species metabolic process GO:0072593 84 0.013
regulation of carbohydrate metabolic process GO:0006109 75 0.013
sensory system development GO:0048880 3 0.013
negative regulation of phosphorus metabolic process GO:0010563 184 0.013
cellular response to lipid GO:0071396 145 0.013
methylation GO:0032259 134 0.013
rho protein signal transduction GO:0007266 32 0.013
learning or memory GO:0007611 148 0.013
compound eye development GO:0048749 1 0.013
regulation of intracellular transport GO:0032386 159 0.013
cognition GO:0050890 149 0.013
cellular ion homeostasis GO:0006873 165 0.013
organic hydroxy compound metabolic process GO:1901615 203 0.013
protein localization to organelle GO:0033365 185 0.013
regulation of establishment of protein localization GO:0070201 181 0.013
positive regulation of nucleotide metabolic process GO:0045981 114 0.013
anatomical structure homeostasis GO:0060249 145 0.013
multicellular organismal reproductive behavior GO:0033057 23 0.013
cardiocyte differentiation GO:0035051 87 0.013
regulation of system process GO:0044057 200 0.013
positive regulation of mapk cascade GO:0043410 170 0.013
negative regulation of cell cycle GO:0045786 123 0.013
telencephalon development GO:0021537 186 0.013
hormone secretion GO:0046879 128 0.013
regulation of ion transmembrane transport GO:0034765 119 0.013
regulation of cell adhesion GO:0030155 154 0.013
cellular response to organic cyclic compound GO:0071407 87 0.013
Human
lipid transport GO:0006869 98 0.013
regulation of neuron projection development GO:0010975 169 0.013
meiosis i GO:0007127 60 0.013
amide transport GO:0042886 138 0.013
morphogenesis of a branching epithelium GO:0061138 193 0.013
carbohydrate derivative biosynthetic process GO:1901137 183 0.013
b cell activation GO:0042113 161 0.013
glucose homeostasis GO:0042593 128 0.013
regulation of cell projection organization GO:0031344 206 0.013
cardiac chamber morphogenesis GO:0003206 93 0.013
neuronal action potential GO:0019228 54 0.012
protein dealkylation GO:0008214 13 0.012
negative regulation of neuron death GO:1901215 98 0.012
meiotic cell cycle process GO:1903046 77 0.012
regeneration GO:0031099 38 0.012
neuron migration GO:0001764 122 0.012
regulation of cytoskeleton organization GO:0051493 122 0.012
regulation of cell activation GO:0050865 289 0.012
muscle system process GO:0003012 141 0.012
regulation of protein transport GO:0051223 163 0.012
neural tube closure GO:0001843 90 0.012
mitotic cell cycle process GO:1903047 159 0.012
positive regulation of kidney development GO:0090184 28 0.012
leukocyte mediated immunity GO:0002443 174 0.012
regulation of hormone levels GO:0010817 211 0.012
respiratory system development GO:0060541 190 0.012
adult behavior GO:0030534 135 0.012
positive regulation of transferase activity GO:0051347 167 0.012
pole plasm assembly GO:0007315 2 0.012
positive regulation of apoptotic process GO:0043065 217 0.012
cellular protein catabolic process GO:0044257 155 0.012
actin cytoskeleton organization GO:0030036 220 0.012
protein oligomerization GO:0051259 67 0.012
nucleotide biosynthetic process GO:0009165 78 0.012
branching morphogenesis of an epithelial tube GO:0048754 159 0.012
neural tube formation GO:0001841 108 0.012
sensory perception of mechanical stimulus GO:0050954 107 0.012
respiratory tube development GO:0030323 167 0.012
hexose metabolic process GO:0019318 98 0.012
tube formation GO:0035148 140 0.012
organ growth GO:0035265 117 0.012
cerebral cortex development GO:0021987 86 0.012
cellular calcium ion homeostasis GO:0006874 119 0.012
negative regulation of organelle organization GO:0010639 90 0.012
regulation of cell motility GO:2000145 236 0.012
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.012
peptide secretion GO:0002790 114 0.011
mitochondrion distribution GO:0048311 4 0.011
blood circulation GO:0008015 195 0.011
negative regulation of neuron apoptotic process GO:0043524 92 0.011
t cell activation GO:0042110 289 0.011
cell growth GO:0016049 130 0.011
divalent inorganic cation transport GO:0072511 178 0.011
mesoderm development GO:0007498 100 0.011
epithelial cell development GO:0002064 159 0.011
somatotropin secreting cell differentiation GO:0060126 4 0.011
organelle assembly GO:0070925 177 0.011
regulation of lymphocyte activation GO:0051249 240 0.011
alcohol metabolic process GO:0006066 116 0.011
neural tube development GO:0021915 160 0.011
macromolecule methylation GO:0043414 120 0.011
digestive system development GO:0055123 200 0.011
ncrna processing GO:0034470 26 0.011
Human
cellular metal ion homeostasis GO:0006875 151 0.011
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.011
maternal determination of anterior posterior axis embryo GO:0008358 2 0.011
gastrulation GO:0007369 116 0.011
organelle localization GO:0051640 179 0.011
response to radiation GO:0009314 165 0.011
digestive tract morphogenesis GO:0048546 147 0.011
regulation of epithelial cell proliferation GO:0050678 141 0.011
circadian rhythm GO:0007623 114 0.011
wnt signaling pathway GO:0016055 188 0.011
dsrna fragmentation GO:0031050 6 0.011
Human
cellular component assembly involved in morphogenesis GO:0010927 139 0.011
b cell differentiation GO:0030183 78 0.011
extrinsic apoptotic signaling pathway GO:0097191 126 0.011
regulation of erk1 and erk2 cascade GO:0070372 71 0.011
negative regulation of phosphorylation GO:0042326 166 0.011
regulation of peptide transport GO:0090087 91 0.011
purine nucleoside monophosphate metabolic process GO:0009126 81 0.011
regulation of transmembrane transport GO:0034762 128 0.011
hindbrain development GO:0030902 128 0.011
pallium development GO:0021543 120 0.011
glucose metabolic process GO:0006006 92 0.011
oogenesis GO:0048477 56 0.011
divalent metal ion transport GO:0070838 172 0.011
single organism nuclear import GO:1902593 95 0.011
inner ear morphogenesis GO:0042472 101 0.011
response to insulin GO:0032868 100 0.011
somite development GO:0061053 81 0.011
defense response to other organism GO:0098542 197 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.011
protein import into nucleus GO:0006606 95 0.011
divalent inorganic cation homeostasis GO:0072507 138 0.011
positive regulation of organelle organization GO:0010638 128 0.011
immune effector process GO:0002252 321 0.011
oocyte anterior posterior axis specification GO:0007314 2 0.011
heart process GO:0003015 94 0.011
regulation of vesicle mediated transport GO:0060627 139 0.011
plasma membrane organization GO:0007009 90 0.011
embryonic skeletal system development GO:0048706 120 0.011
rhythmic process GO:0048511 174 0.010
engulfment of apoptotic cell GO:0043652 3 0.010
regulation of anatomical structure size GO:0090066 178 0.010
ribonucleoside monophosphate metabolic process GO:0009161 80 0.010
production of molecular mediator of immune response GO:0002440 103 0.010
monosaccharide metabolic process GO:0005996 106 0.010
bone morphogenesis GO:0060349 78 0.010
protein import GO:0017038 101 0.010
regulation of gene silencing by rna GO:0060966 5 0.010
nuclear import GO:0051170 95 0.010
peptide hormone secretion GO:0030072 109 0.010
nerve development GO:0021675 67 0.010
rna interference GO:0016246 2 0.010
wound healing GO:0042060 157 0.010
extracellular matrix organization GO:0030198 147 0.010
protein maturation GO:0051604 176 0.010
response to peptide hormone GO:0043434 127 0.010
regulation of ion transport GO:0043269 215 0.010
lateral inhibition GO:0046331 1 0.010
connective tissue development GO:0061448 179 0.010
nucleoside monophosphate metabolic process GO:0009123 85 0.010
ear morphogenesis GO:0042471 118 0.010
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.010

Lin28b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.026
nervous system disease DOID:863 0 0.026
musculoskeletal system disease DOID:17 0 0.018
connective tissue disease DOID:65 0 0.012
central nervous system disease DOID:331 0 0.011
bone disease DOID:0080001 0 0.010
sensory system disease DOID:0050155 0 0.010