|
|
smoothened signaling pathway
|
GO:0007224 |
105 |
0.921
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.854
|
Mouse |
|
|
appendage development
|
GO:0048736 |
166 |
0.839
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.818
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.804
|
Fly |
|
|
axon guidance
|
GO:0007411 |
141 |
0.800
|
Mouse |
|
|
mapk cascade
|
GO:0000165 |
281 |
0.787
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.753
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
93 |
0.749
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.721
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.705
|
|
|
|
regulation of smoothened signaling pathway
|
GO:0008589 |
58 |
0.679
|
Fly |
|
|
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry
|
GO:1900094 |
2 |
0.677
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.614
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.614
|
|
|
|
positive regulation of smoothened signaling pathway
|
GO:0045880 |
23 |
0.612
|
Fly |
|
|
hindbrain morphogenesis
|
GO:0021575 |
46 |
0.600
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.595
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.585
|
|
|
|
telencephalon development
|
GO:0021537 |
186 |
0.581
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.571
|
Mouse |
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.570
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.515
|
|
|
|
neural tube development
|
GO:0021915 |
160 |
0.500
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.498
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.486
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
112 |
0.485
|
|
|
|
regulation of bmp signaling pathway
|
GO:0030510 |
60 |
0.468
|
|
|
|
spinal cord development
|
GO:0021510 |
81 |
0.467
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.461
|
Mouse |
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.460
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.455
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.439
|
|
|
|
nodal signaling pathway involved in determination of lateral mesoderm left right asymmetry
|
GO:1900164 |
2 |
0.437
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.433
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.431
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.424
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.406
|
|
|
|
limb development
|
GO:0060173 |
166 |
0.404
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.374
|
|
|
|
pallium development
|
GO:0021543 |
120 |
0.369
|
|
|
|
central nervous system neuron differentiation
|
GO:0021953 |
162 |
0.359
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.350
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.333
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.330
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.329
|
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.322
|
|
|
|
metanephric mesenchymal cell proliferation involved in metanephros development
|
GO:0072136 |
2 |
0.315
|
|
|
|
positive regulation of neural precursor cell proliferation
|
GO:2000179 |
42 |
0.315
|
|
|
|
neural tube closure
|
GO:0001843 |
90 |
0.313
|
|
|
|
cerebral cortex development
|
GO:0021987 |
86 |
0.311
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.308
|
Mouse |
|
|
nodal signaling pathway involved in determination of left right asymmetry
|
GO:0038107 |
2 |
0.301
|
|
|
|
neural tube formation
|
GO:0001841 |
108 |
0.297
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.297
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.293
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.271
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.264
|
|
|
|
cell proliferation in hindbrain
|
GO:0021534 |
10 |
0.263
|
|
|
|
cell fate specification
|
GO:0001708 |
72 |
0.259
|
|
|
|
striated muscle cell development
|
GO:0055002 |
125 |
0.256
|
Mouse |
|
|
regulation of myoblast differentiation
|
GO:0045661 |
29 |
0.254
|
Mouse |
|
|
extracellular structure organization
|
GO:0043062 |
148 |
0.253
|
|
|
|
ear morphogenesis
|
GO:0042471 |
118 |
0.253
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.252
|
|
|
|
regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis
|
GO:0072039 |
4 |
0.243
|
|
|
|
central nervous system projection neuron axonogenesis
|
GO:0021952 |
21 |
0.242
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.236
|
|
|
|
positive regulation of striated muscle tissue development
|
GO:0045844 |
31 |
0.229
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.229
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.223
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.222
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.221
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.221
|
|
|
|
phagocytosis
|
GO:0006909 |
66 |
0.216
|
|
|
|
hindbrain development
|
GO:0030902 |
128 |
0.216
|
|
|
|
regulation of alpha beta t cell differentiation
|
GO:0046637 |
35 |
0.214
|
|
|
|
myotube cell development
|
GO:0014904 |
60 |
0.209
|
Mouse |
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.204
|
|
|
|
spinal cord dorsal ventral patterning
|
GO:0021513 |
23 |
0.203
|
|
|
|
limb morphogenesis
|
GO:0035108 |
149 |
0.203
|
|
|
|
muscle fiber development
|
GO:0048747 |
76 |
0.200
|
Mouse |
|
|
tube closure
|
GO:0060606 |
91 |
0.199
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
71 |
0.199
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.196
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.195
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.194
|
|
|
|
thyroid stimulating hormone secreting cell differentiation
|
GO:0060129 |
4 |
0.191
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.189
|
|
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
139 |
0.189
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.188
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
70 |
0.186
|
|
|
|
nephrogenic mesenchyme morphogenesis
|
GO:0072134 |
2 |
0.185
|
|
|
|
cerebral cortex cell migration
|
GO:0021795 |
44 |
0.181
|
|
|
|
skeletal muscle fiber development
|
GO:0048741 |
58 |
0.181
|
Mouse |
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.180
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.179
|
|
|
|
positive regulation of tendon cell differentiation
|
GO:2001051 |
1 |
0.178
|
|
|
|
syncytium formation
|
GO:0006949 |
43 |
0.176
|
|
|
|
lens development in camera type eye
|
GO:0002088 |
62 |
0.175
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.174
|
|
|
|
embryonic camera type eye development
|
GO:0031076 |
36 |
0.173
|
|
|
|
embryonic nail plate morphogenesis
|
GO:0035880 |
3 |
0.173
|
|
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.172
|
|
|
|
hepaticobiliary system development
|
GO:0061008 |
67 |
0.172
|
|
|
|
positive regulation of stem cell proliferation
|
GO:2000648 |
59 |
0.171
|
|
|
|
tube formation
|
GO:0035148 |
140 |
0.170
|
|
|
|
floor plate morphogenesis
|
GO:0033505 |
3 |
0.169
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.168
|
|
|
|
inner ear morphogenesis
|
GO:0042472 |
101 |
0.161
|
|
|
|
embryonic skeletal system development
|
GO:0048706 |
120 |
0.160
|
|
|
|
cerebellar granule cell precursor proliferation
|
GO:0021930 |
10 |
0.159
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
88 |
0.158
|
|
|
|
formation of radial glial scaffolds
|
GO:0021943 |
4 |
0.158
|
|
|
|
mesenchymal cell proliferation involved in ureter development
|
GO:0072198 |
4 |
0.157
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.155
|
|
|
|
embryonic skeletal joint development
|
GO:0072498 |
13 |
0.155
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.154
|
|
|
|
developmental cell growth
|
GO:0048588 |
84 |
0.153
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.149
|
|
|
|
regulation of protein binding
|
GO:0043393 |
60 |
0.149
|
|
|
|
notch signaling pathway
|
GO:0007219 |
71 |
0.149
|
Fly |
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.148
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.147
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.147
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.146
|
|
|
|
axial mesoderm formation
|
GO:0048320 |
3 |
0.145
|
|
|
|
appendage morphogenesis
|
GO:0035107 |
149 |
0.145
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.144
|
|
|
|
cilium morphogenesis
|
GO:0060271 |
102 |
0.143
|
|
|
|
regulation of osteoblast proliferation
|
GO:0033688 |
15 |
0.143
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.141
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.139
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.138
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.137
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.137
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.136
|
|
|
|
positive regulation of hh target transcription factor activity
|
GO:0007228 |
3 |
0.136
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.135
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
26 |
0.135
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.135
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.133
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.132
|
|
|
|
embryonic appendage morphogenesis
|
GO:0035113 |
126 |
0.132
|
|
|
|
positive regulation of growth
|
GO:0045927 |
104 |
0.132
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.130
|
|
|
|
progesterone secretion
|
GO:0042701 |
1 |
0.129
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.129
|
|
|
|
regulation of notch signaling pathway
|
GO:0008593 |
35 |
0.128
|
Fly |
|
|
oogenesis
|
GO:0048477 |
56 |
0.125
|
|
|
|
negative regulation of bmp signaling pathway
|
GO:0030514 |
35 |
0.125
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.124
|
|
|
|
embryonic genitalia morphogenesis
|
GO:0030538 |
4 |
0.123
|
|
|
|
blood circulation
|
GO:0008015 |
195 |
0.123
|
|
|
|
metanephric mesenchyme morphogenesis
|
GO:0072133 |
4 |
0.123
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.122
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.121
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.121
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.120
|
|
|
|
cell recognition
|
GO:0008037 |
83 |
0.120
|
|
|
|
telencephalon cell migration
|
GO:0022029 |
55 |
0.119
|
|
|
|
wnt signaling pathway involved in somitogenesis
|
GO:0090244 |
4 |
0.119
|
|
|
|
forebrain radial glial cell differentiation
|
GO:0021861 |
4 |
0.119
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
151 |
0.118
|
|
|
|
skeletal system morphogenesis
|
GO:0048705 |
203 |
0.117
|
|
|
|
regulation of engulfment of apoptotic cell
|
GO:1901074 |
2 |
0.117
|
|
|
|
mesenchymal cell apoptotic process involved in nephron morphogenesis
|
GO:1901145 |
4 |
0.115
|
|
|
|
axial mesodermal cell fate commitment
|
GO:0048322 |
1 |
0.114
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.113
|
|
|
|
lipid localization
|
GO:0010876 |
126 |
0.113
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.110
|
|
|
|
cell proliferation involved in kidney development
|
GO:0072111 |
14 |
0.110
|
|
|
|
negative regulation of planar cell polarity pathway involved in heart morphogenesis
|
GO:2000160 |
1 |
0.110
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
138 |
0.110
|
|
|
|
spinal cord motor neuron differentiation
|
GO:0021522 |
35 |
0.109
|
|
|
|
transforming growth factor beta receptor signaling pathway involved in primitive streak formation
|
GO:0090010 |
1 |
0.108
|
|
|
|
establishment of planar polarity involved in neural tube closure
|
GO:0090177 |
15 |
0.108
|
|
|
|
spinal cord patterning
|
GO:0021511 |
25 |
0.107
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.107
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.105
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
88 |
0.105
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.105
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.105
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.104
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
58 |
0.104
|
|
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.103
|
|
|
|
regulation of epithelial to mesenchymal transition
|
GO:0010717 |
22 |
0.103
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.103
|
|
|
|
osteoblast proliferation
|
GO:0033687 |
18 |
0.103
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.103
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.102
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.102
|
|
|
|
regulation of skeletal muscle fiber development
|
GO:0048742 |
36 |
0.101
|
Mouse |
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.101
|
|
|
|
somitogenesis
|
GO:0001756 |
69 |
0.100
|
|
|
|
embryonic skeletal system morphogenesis
|
GO:0048704 |
91 |
0.100
|
|
|
|
positive regulation of secondary heart field cardioblast proliferation
|
GO:0072513 |
4 |
0.099
|
|
|
|
kidney mesenchymal cell proliferation
|
GO:0072135 |
2 |
0.099
|
|
|
|
embryonic digit morphogenesis
|
GO:0042733 |
56 |
0.099
|
|
|
|
axial mesodermal cell fate specification
|
GO:0048327 |
1 |
0.098
|
|
|
|
negative regulation of cell fate specification
|
GO:0009996 |
4 |
0.098
|
|
|
|
neuron projection extension
|
GO:1990138 |
64 |
0.098
|
|
|
|
neural tube patterning
|
GO:0021532 |
43 |
0.096
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.096
|
|
|
|
epithelial tube formation
|
GO:0072175 |
130 |
0.096
|
|
|
|
inner ear receptor cell differentiation
|
GO:0060113 |
61 |
0.096
|
|
|
|
liver development
|
GO:0001889 |
66 |
0.096
|
|
|
|
regulation of striated muscle cell differentiation
|
GO:0051153 |
81 |
0.095
|
Mouse |
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.095
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.093
|
|
|
|
cerebellum vasculature development
|
GO:0061300 |
1 |
0.092
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.092
|
|
|
|
body morphogenesis
|
GO:0010171 |
45 |
0.092
|
|
|
|
syncytiotrophoblast cell differentiation involved in labyrinthine layer development
|
GO:0060715 |
2 |
0.091
|
|
|
|
gastrulation
|
GO:0007369 |
116 |
0.090
|
|
|
|
determination of left right symmetry
|
GO:0007368 |
80 |
0.089
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.089
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.089
|
|
|
|
negative regulation of hormone biosynthetic process
|
GO:0032353 |
4 |
0.088
|
|
|
|
muscle contraction
|
GO:0006936 |
101 |
0.088
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.088
|
|
|
|
odontogenesis
|
GO:0042476 |
78 |
0.086
|
|
|
|
cerebellum development
|
GO:0021549 |
77 |
0.086
|
|
|
|
preganglionic parasympathetic nervous system development
|
GO:0021783 |
17 |
0.086
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.086
|
|
|
|
ensheathment of neurons
|
GO:0007272 |
76 |
0.086
|
|
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
61 |
0.085
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.085
|
|
|
|
heart morphogenesis
|
GO:0003007 |
178 |
0.085
|
|
|
|
regulation of timing of cell differentiation
|
GO:0048505 |
11 |
0.084
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.084
|
|
|
|
retina morphogenesis in camera type eye
|
GO:0060042 |
45 |
0.084
|
|
|
|
positive regulation of alpha beta t cell differentiation
|
GO:0046638 |
28 |
0.083
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.082
|
|
|
|
stem cell proliferation
|
GO:0072089 |
117 |
0.082
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.082
|
|
|
|
labyrinthine layer development
|
GO:0060711 |
49 |
0.081
|
|
|
|
spermatid differentiation
|
GO:0048515 |
115 |
0.081
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
82 |
0.081
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.081
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
70 |
0.080
|
|
|
|
lung development
|
GO:0030324 |
164 |
0.080
|
|
|
|
smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation
|
GO:0021938 |
4 |
0.079
|
|
|
|
cilium assembly
|
GO:0042384 |
81 |
0.079
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.079
|
|
|
|
t cell differentiation involved in immune response
|
GO:0002292 |
30 |
0.079
|
|
|
|
negative regulation of kidney development
|
GO:0090185 |
15 |
0.079
|
|
|
|
kidney development
|
GO:0001822 |
213 |
0.079
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.078
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.078
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
128 |
0.078
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.078
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.078
|
|
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
53 |
0.078
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.078
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.077
|
|
|
|
microglia differentiation
|
GO:0014004 |
2 |
0.077
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.077
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.077
|
|
|
|
heart formation
|
GO:0060914 |
16 |
0.076
|
|
|
|
negative regulation of sterol transport
|
GO:0032372 |
4 |
0.076
|
|
|
|
nephron morphogenesis
|
GO:0072028 |
69 |
0.076
|
|
|
|
amide transport
|
GO:0042886 |
138 |
0.075
|
|
|
|
cardiocyte differentiation
|
GO:0035051 |
87 |
0.075
|
|
|
|
wnt signaling pathway involved in forebrain neuroblast division
|
GO:0021874 |
2 |
0.075
|
|
|
|
organelle fission
|
GO:0048285 |
170 |
0.074
|
|
|
|
muscle cell fate specification
|
GO:0042694 |
1 |
0.074
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.074
|
|
|
|
male sex determination
|
GO:0030238 |
14 |
0.074
|
|
|
|
negative regulation of phospholipase activity
|
GO:0010519 |
4 |
0.074
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.074
|
|
|
|
left lung development
|
GO:0060459 |
4 |
0.073
|
|
|
|
positive regulation of homeostatic process
|
GO:0032846 |
64 |
0.073
|
|
|
|
mesoderm formation
|
GO:0001707 |
62 |
0.073
|
|
|
|
germ line stem cell division
|
GO:0042078 |
2 |
0.073
|
|
|
|
kidney mesenchyme morphogenesis
|
GO:0072131 |
4 |
0.072
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.072
|
|
|
|
embryonic placenta development
|
GO:0001892 |
98 |
0.072
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
68 |
0.072
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.072
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
130 |
0.071
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.070
|
|
|
|
embryonic placenta morphogenesis
|
GO:0060669 |
25 |
0.070
|
|
|
|
epithelial cell morphogenesis
|
GO:0003382 |
41 |
0.069
|
|
|
|
inhibition of neuroepithelial cell differentiation
|
GO:0002085 |
2 |
0.069
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.069
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.069
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.068
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.068
|
|
|
|
negative regulation of stem cell maintenance
|
GO:1902455 |
4 |
0.067
|
|
|
|
skeletal muscle cell differentiation
|
GO:0035914 |
66 |
0.066
|
|
|
|
trophectodermal cellular morphogenesis
|
GO:0001831 |
3 |
0.066
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.066
|
|
|
|
negative regulation of gastrulation
|
GO:2000542 |
3 |
0.066
|
|
|
|
negative regulation of t helper 2 cell differentiation
|
GO:0045629 |
4 |
0.065
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.065
|
|
|
|
spermatid development
|
GO:0007286 |
108 |
0.065
|
|
|
|
iron ion homeostasis
|
GO:0055072 |
36 |
0.065
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.065
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.064
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.064
|
|
|
|
oligodendrocyte development
|
GO:0014003 |
20 |
0.064
|
|
|
|
regulation of protein stability
|
GO:0031647 |
52 |
0.064
|
|
|
|
forebrain cell migration
|
GO:0021885 |
58 |
0.063
|
|
|
|
asymmetric stem cell division
|
GO:0098722 |
3 |
0.063
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.063
|
|
|
|
establishment of neuroblast polarity
|
GO:0045200 |
1 |
0.063
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.063
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
81 |
0.063
|
|
|
|
glossopharyngeal nerve morphogenesis
|
GO:0021615 |
4 |
0.063
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
88 |
0.063
|
|
|
|
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090100 |
43 |
0.063
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.063
|
|
|
|
renal system process
|
GO:0003014 |
48 |
0.063
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.062
|
|
|
|
regulation of muscle tissue development
|
GO:1901861 |
97 |
0.062
|
|
|
|
positive regulation of endothelial cell proliferation
|
GO:0001938 |
17 |
0.062
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.062
|
|
|
|
roof plate formation
|
GO:0021509 |
1 |
0.061
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.061
|
|
|
|
peptide transport
|
GO:0015833 |
133 |
0.061
|
|
|
|
negative regulation of execution phase of apoptosis
|
GO:1900118 |
4 |
0.060
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.060
|
|
|
|
cell proliferation in external granule layer
|
GO:0021924 |
10 |
0.060
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.060
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.060
|
|
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.059
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
73 |
0.059
|
|
|
|
lens morphogenesis in camera type eye
|
GO:0002089 |
24 |
0.059
|
|
|
|
midbrain development
|
GO:0030901 |
35 |
0.059
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.059
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.058
|
|
|
|
embryonic skeletal joint morphogenesis
|
GO:0060272 |
11 |
0.058
|
|
|
|
meiotic nuclear division
|
GO:0007126 |
115 |
0.058
|
|
|
|
regulation of myotube differentiation
|
GO:0010830 |
62 |
0.058
|
Mouse |
|
|
organic acid transport
|
GO:0015849 |
101 |
0.058
|
|
|
|
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis
|
GO:0061350 |
2 |
0.058
|
|
|
|
extracellular matrix organization
|
GO:0030198 |
147 |
0.058
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.058
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.058
|
|
|
|
carbohydrate homeostasis
|
GO:0033500 |
128 |
0.058
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.058
|
|
|
|
b cell differentiation
|
GO:0030183 |
78 |
0.058
|
|
|
|
embryonic eye morphogenesis
|
GO:0048048 |
29 |
0.057
|
|
|
|
multi organism reproductive behavior
|
GO:0044705 |
29 |
0.057
|
|
|
|
renal tubule development
|
GO:0061326 |
87 |
0.057
|
|
|
|
limbic system development
|
GO:0021761 |
72 |
0.057
|
|
|
|
regulation of endothelial cell proliferation
|
GO:0001936 |
23 |
0.057
|
|
|
|
protein import
|
GO:0017038 |
101 |
0.056
|
|
|
|
pituitary gland development
|
GO:0021983 |
38 |
0.056
|
|
|
|
regulation of fat cell differentiation
|
GO:0045598 |
81 |
0.056
|
|
|
|
respiratory system development
|
GO:0060541 |
190 |
0.056
|
|
|
|
nuclear import
|
GO:0051170 |
95 |
0.056
|
|
|
|
synapse organization
|
GO:0050808 |
125 |
0.055
|
|
|
|
trachea cartilage morphogenesis
|
GO:0060535 |
4 |
0.055
|
|
|
|
nephrogenic mesenchyme development
|
GO:0072076 |
3 |
0.055
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.055
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.055
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
47 |
0.054
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.054
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.054
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.054
|
|
|
|
placenta development
|
GO:0001890 |
140 |
0.054
|
|
|
|
fibroblast growth factor receptor signaling pathway
|
GO:0008543 |
46 |
0.054
|
|
|
|
lung morphogenesis
|
GO:0060425 |
50 |
0.054
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
159 |
0.054
|
|
|
|
positive regulation of glial cell differentiation
|
GO:0045687 |
21 |
0.054
|
|
|
|
homeostasis of number of cells within a tissue
|
GO:0048873 |
25 |
0.054
|
|
|
|
thymic t cell selection
|
GO:0045061 |
22 |
0.054
|
|
|
|
bone morphogenesis
|
GO:0060349 |
78 |
0.053
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.053
|
|
|
|
myoblast differentiation
|
GO:0045445 |
52 |
0.052
|
Mouse |
|
|
positive regulation of osteoblast proliferation
|
GO:0033690 |
9 |
0.052
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
68 |
0.052
|
|
|
|
labyrinthine layer morphogenesis
|
GO:0060713 |
21 |
0.052
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.052
|
|
|
|
odontogenesis of dentin containing tooth
|
GO:0042475 |
66 |
0.052
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
127 |
0.052
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.051
|
|
|
|
negative regulation of cardiac chamber morphogenesis
|
GO:1901220 |
2 |
0.051
|
|
|
|
regulation of non canonical wnt signaling pathway
|
GO:2000050 |
12 |
0.051
|
|
|
|
embryonic limb morphogenesis
|
GO:0030326 |
126 |
0.051
|
|
|
|
positive regulation of alpha beta t cell activation
|
GO:0046635 |
39 |
0.050
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.050
|
|
|
|
negative regulation of prostatic bud formation
|
GO:0060686 |
4 |
0.050
|
|
|
|
positive regulation of mesenchymal cell proliferation involved in ureter development
|
GO:2000729 |
3 |
0.050
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.050
|
|
|
|
cell differentiation in spinal cord
|
GO:0021515 |
53 |
0.050
|
|
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
42 |
0.050
|
|
|
|
specification of organ position
|
GO:0010159 |
3 |
0.049
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.049
|
|
|
|
tendon cell differentiation
|
GO:0035990 |
4 |
0.049
|
|
|
|
negative regulation of alpha beta t cell activation
|
GO:0046636 |
18 |
0.049
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.049
|
|
|
|
forebrain neuron differentiation
|
GO:0021879 |
52 |
0.049
|
|
|
|
trophectodermal cell differentiation
|
GO:0001829 |
21 |
0.049
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.048
|
|
|
|
positive regulation of neuron projection regeneration
|
GO:0070572 |
2 |
0.048
|
|
|
|
central nervous system neuron axonogenesis
|
GO:0021955 |
28 |
0.048
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.048
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
65 |
0.048
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.048
|
|
|
|
ventral spinal cord interneuron differentiation
|
GO:0021514 |
16 |
0.048
|
|
|
|
renal system development
|
GO:0072001 |
225 |
0.048
|
|
|
|
blood coagulation
|
GO:0007596 |
76 |
0.048
|
|
|
|
dendritic spine maintenance
|
GO:0097062 |
4 |
0.048
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.048
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.048
|
|
|
|
negative regulation of hepatocyte differentiation
|
GO:0070367 |
1 |
0.048
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.048
|
|
|
|
regulation of mesenchymal cell proliferation involved in ureter development
|
GO:0072199 |
3 |
0.047
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.047
|
|
|
|
anion transport
|
GO:0006820 |
177 |
0.047
|
|
|
|
positive regulation of muscle cell differentiation
|
GO:0051149 |
39 |
0.047
|
Mouse |
|
|
carboxylic acid transport
|
GO:0046942 |
100 |
0.046
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter involved in smooth muscle cell differentiation
|
GO:2000721 |
2 |
0.046
|
|
|
|
adenylate cyclase inhibiting g protein coupled receptor signaling pathway
|
GO:0007193 |
20 |
0.046
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.046
|
|
|
|
negative regulation of keratinocyte differentiation
|
GO:0045617 |
4 |
0.046
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.046
|
|
|
|
diencephalon development
|
GO:0021536 |
63 |
0.045
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
123 |
0.045
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiation
|
GO:0003257 |
3 |
0.045
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.045
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.045
|
|
|
|
nephron development
|
GO:0072006 |
109 |
0.045
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.045
|
|
|
|
internal protein amino acid acetylation
|
GO:0006475 |
42 |
0.045
|
|
|
|
organelle assembly
|
GO:0070925 |
177 |
0.045
|
|
|
|
regulation of neural retina development
|
GO:0061074 |
3 |
0.045
|
|
|
|
female gamete generation
|
GO:0007292 |
74 |
0.044
|
|
|
|
cranial nerve development
|
GO:0021545 |
41 |
0.044
|
|
|
|
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation
|
GO:2000802 |
1 |
0.044
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.044
|
|
|
|
carbon catabolite activation of transcription
|
GO:0045991 |
4 |
0.044
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
126 |
0.044
|
|
|
|
positive regulation of bmp signaling pathway
|
GO:0030513 |
23 |
0.044
|
|
|
|
regulation of phospholipase c activity
|
GO:1900274 |
3 |
0.044
|
|
|
|
trachea formation
|
GO:0060440 |
3 |
0.044
|
|
|
|
positive regulation of myoblast differentiation
|
GO:0045663 |
8 |
0.044
|
Mouse |
|
|
nephron tubule morphogenesis
|
GO:0072078 |
68 |
0.044
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.044
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.044
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
130 |
0.044
|
|
|
|
axis elongation involved in somitogenesis
|
GO:0090245 |
4 |
0.043
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
159 |
0.043
|
|
|
|
brain morphogenesis
|
GO:0048854 |
32 |
0.043
|
|
|
|
positive regulation of ossification
|
GO:0045778 |
47 |
0.043
|
|
|
|
hormone metabolic process
|
GO:0042445 |
86 |
0.043
|
|
|
|
axon ensheathment
|
GO:0008366 |
76 |
0.043
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.043
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.043
|
|
|
|
epiblast cell extraembryonic ectoderm cell signaling involved in anterior posterior axis specification
|
GO:0060802 |
1 |
0.042
|
|
|
|
primary neural tube formation
|
GO:0014020 |
95 |
0.042
|
|
|
|
regulation of smooth muscle contraction
|
GO:0006940 |
22 |
0.042
|
|
|
|
regulation of muscle system process
|
GO:0090257 |
80 |
0.042
|
|
|
|
negative regulation of t cell activation
|
GO:0050868 |
65 |
0.042
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
96 |
0.042
|
|
|
|
smooth muscle tissue development
|
GO:0048745 |
22 |
0.042
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.042
|
|
|
|
cerebellum vasculature morphogenesis
|
GO:0061301 |
1 |
0.042
|
|
|
|
heart trabecula formation
|
GO:0060347 |
14 |
0.041
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.041
|
|
|
|
cell growth
|
GO:0016049 |
130 |
0.041
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.041
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.041
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.041
|
|
|
|
regulation of establishment of planar polarity
|
GO:0090175 |
28 |
0.041
|
|
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.041
|
|
|
|
regulation of anion transport
|
GO:0044070 |
27 |
0.040
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.040
|
|
|
|
c21 steroid hormone biosynthetic process
|
GO:0006700 |
3 |
0.040
|
|
|
|
endodermal cell fate specification
|
GO:0001714 |
4 |
0.040
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.040
|
|
|
|
blastocyst development
|
GO:0001824 |
80 |
0.039
|
|
|
|
regulation of monocyte extravasation
|
GO:2000437 |
2 |
0.039
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.039
|
|
|
|
carbon catabolite activation of transcription from rna polymerase ii promoter
|
GO:0000436 |
4 |
0.039
|
|
|
|
cardiac septum development
|
GO:0003279 |
59 |
0.039
|
|
|
|
megakaryocyte differentiation
|
GO:0030219 |
26 |
0.039
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.039
|
|
|
|
heart field specification
|
GO:0003128 |
6 |
0.039
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.039
|
|
|
|
neuroblast differentiation
|
GO:0014016 |
2 |
0.039
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.039
|
|
|
|
determination of heart left right asymmetry
|
GO:0061371 |
48 |
0.039
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.039
|
|
|
|
kidney mesenchyme development
|
GO:0072074 |
14 |
0.038
|
|
|
|
bone development
|
GO:0060348 |
120 |
0.038
|
|
|
|
regulation of endothelial cell apoptotic process
|
GO:2000351 |
9 |
0.038
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
266 |
0.038
|
|
|
|
mesenchyme development
|
GO:0060485 |
152 |
0.038
|
|
|
|
regulation of stem cell proliferation
|
GO:0072091 |
78 |
0.038
|
|
|
|
signal transduction downstream of smoothened
|
GO:0007227 |
4 |
0.038
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
65 |
0.038
|
|
