Mus musculus

26 known processes

Sord

sorbitol dehydrogenase

(Aliases: MGC31355,Sdh1,Sdh-1,Sodh-1)

Sord biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oxidation reduction process GO:0055114 342 0.651
cellular modified amino acid metabolic process GO:0006575 63 0.366
cofactor metabolic process GO:0051186 80 0.261
glutathione metabolic process GO:0006749 16 0.258
cellular lipid metabolic process GO:0044255 323 0.228
cellular amino acid metabolic process GO:0006520 103 0.193
sulfur compound metabolic process GO:0006790 100 0.149
carboxylic acid catabolic process GO:0046395 51 0.111
fatty acid metabolic process GO:0006631 121 0.104
alpha amino acid metabolic process GO:1901605 59 0.094
transmembrane transport GO:0055085 412 0.089
nucleobase containing small molecule metabolic process GO:0055086 352 0.085
cellular amide metabolic process GO:0043603 58 0.079
peptide metabolic process GO:0006518 46 0.077
nitrogen compound transport GO:0071705 271 0.077
monocarboxylic acid metabolic process GO:0032787 191 0.077
organic acid catabolic process GO:0016054 51 0.072
purine containing compound metabolic process GO:0072521 311 0.067
regulation of cellular ketone metabolic process GO:0010565 66 0.066
generation of precursor metabolites and energy GO:0006091 103 0.062
glycosyl compound metabolic process GO:1901657 246 0.055
response to organonitrogen compound GO:0010243 246 0.054
small molecule biosynthetic process GO:0044283 132 0.054
cellular ketone metabolic process GO:0042180 84 0.054
alcohol metabolic process GO:0006066 116 0.054
amine metabolic process GO:0009308 45 0.052
nucleoside metabolic process GO:0009116 246 0.052
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.051
heterocycle catabolic process GO:0046700 280 0.050
regulation of cellular amine metabolic process GO:0033238 20 0.050
reactive oxygen species metabolic process GO:0072593 84 0.049
organic cyclic compound catabolic process GO:1901361 295 0.049
organonitrogen compound catabolic process GO:1901565 264 0.048
organic acid biosynthetic process GO:0016053 86 0.048
nucleotide metabolic process GO:0009117 332 0.047
carboxylic acid biosynthetic process GO:0046394 86 0.045
small molecule catabolic process GO:0044282 71 0.042
Human
regulation of cellular amino acid metabolic process GO:0006521 5 0.042
response to inorganic substance GO:0010035 96 0.041
xenobiotic catabolic process GO:0042178 1 0.040
negative regulation of cellular protein metabolic process GO:0032269 247 0.040
purine nucleoside metabolic process GO:0042278 241 0.039
response to organic cyclic compound GO:0014070 198 0.039
organic hydroxy compound metabolic process GO:1901615 203 0.038
nucleoside phosphate metabolic process GO:0006753 338 0.038
cellular amine metabolic process GO:0044106 44 0.038
cellular amino acid biosynthetic process GO:0008652 22 0.037
cation transport GO:0006812 399 0.036
lipid biosynthetic process GO:0008610 179 0.036
organonitrogen compound biosynthetic process GO:1901566 192 0.036
nucleoside triphosphate metabolic process GO:0009141 230 0.036
response to acid chemical GO:0001101 111 0.035
regulation of reactive oxygen species metabolic process GO:2000377 40 0.035
cellular response to organonitrogen compound GO:0071417 145 0.033
anion transport GO:0006820 177 0.033
nitrobenzene metabolic process GO:0018916 1 0.033
cellular nitrogen compound catabolic process GO:0044270 280 0.033
response to oxidative stress GO:0006979 123 0.031
fat cell differentiation GO:0045444 160 0.031
energy derivation by oxidation of organic compounds GO:0015980 77 0.031
coenzyme metabolic process GO:0006732 52 0.031
peptidyl amino acid modification GO:0018193 336 0.030
aromatic compound catabolic process GO:0019439 286 0.030
purine nucleotide metabolic process GO:0006163 302 0.029
positive regulation of cellular amine metabolic process GO:0033240 5 0.029
organelle fission GO:0048285 170 0.029
protein catabolic process GO:0030163 221 0.029
ribonucleoside triphosphate metabolic process GO:0009199 220 0.028
positive regulation of apoptotic process GO:0043065 217 0.028
negative regulation of phosphate metabolic process GO:0045936 184 0.028
cellular macromolecule catabolic process GO:0044265 206 0.028
purine ribonucleotide metabolic process GO:0009150 290 0.028
regulation of membrane potential GO:0042391 192 0.027
cellular amino acid catabolic process GO:0009063 25 0.027
neutral lipid metabolic process GO:0006638 57 0.027
macromolecule catabolic process GO:0009057 281 0.026
nuclear division GO:0000280 158 0.026
benzene containing compound metabolic process GO:0042537 5 0.026
positive regulation of protein modification process GO:0031401 299 0.026
alpha amino acid catabolic process GO:1901606 18 0.026
negative regulation of monocyte chemotactic protein 1 production GO:0071638 1 0.025
ribonucleoside metabolic process GO:0009119 245 0.025
response to nitrosative stress GO:0051409 1 0.025
cellular lipid catabolic process GO:0044242 52 0.025
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.025
translation GO:0006412 93 0.025
multicellular organismal signaling GO:0035637 91 0.024
monocyte chemotactic protein 1 production GO:0071605 1 0.024
spermatogenesis GO:0007283 284 0.024
regulation of cellular catabolic process GO:0031329 242 0.024
negative regulation of protein modification process GO:0031400 163 0.023
negative regulation of protein phosphorylation GO:0001933 126 0.023
posttranscriptional regulation of gene expression GO:0010608 155 0.023
negative regulation of intracellular signal transduction GO:1902532 167 0.023
purine ribonucleoside metabolic process GO:0046128 241 0.023
mitochondrion organization GO:0007005 134 0.023
dephosphorylation GO:0016311 129 0.022
negative regulation of phosphorylation GO:0042326 166 0.022
organic acid transport GO:0015849 101 0.022
carbohydrate metabolic process GO:0005975 230 0.022
positive regulation of programmed cell death GO:0043068 218 0.022
cation transmembrane transport GO:0098655 266 0.022
endomembrane system organization GO:0010256 147 0.021
negative regulation of molecular function GO:0044092 258 0.021
negative regulation of cellular amine metabolic process GO:0033239 1 0.021
peptide transport GO:0015833 133 0.021
negative regulation of cellular component organization GO:0051129 194 0.021
sterol metabolic process GO:0016125 58 0.020
response to extracellular stimulus GO:0009991 127 0.020
regulation of apoptotic signaling pathway GO:2001233 197 0.020
negative regulation of protein metabolic process GO:0051248 282 0.020
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.020
regulation of organelle organization GO:0033043 289 0.020
purine nucleoside triphosphate metabolic process GO:0009144 226 0.020
response to amino acid GO:0043200 37 0.020
ubiquitin dependent protein catabolic process GO:0006511 129 0.020
carnitine transmembrane transport GO:1902603 3 0.020
short chain fatty acid catabolic process GO:0019626 2 0.020
carboxylic acid transport GO:0046942 100 0.019
response to nutrient levels GO:0031667 109 0.019
muscle tissue development GO:0060537 308 0.019
nucleoside phosphate catabolic process GO:1901292 222 0.019
steroid metabolic process GO:0008202 119 0.019
negative regulation of phosphorus metabolic process GO:0010563 184 0.019
lipid catabolic process GO:0016042 69 0.019
cellular homeostasis GO:0019725 240 0.019
ribose phosphate metabolic process GO:0019693 291 0.019
meiotic cell cycle GO:0051321 122 0.019
histone modification GO:0016570 159 0.018
sensory organ morphogenesis GO:0090596 242 0.018
dna metabolic process GO:0006259 303 0.018
amide transport GO:0042886 138 0.018
organic anion transport GO:0015711 137 0.018
cell type specific apoptotic process GO:0097285 268 0.018
response to peptide GO:1901652 136 0.018
cellular response to organic cyclic compound GO:0071407 87 0.017
response to light stimulus GO:0009416 135 0.017
protein ubiquitination GO:0016567 171 0.017
lipid localization GO:0010876 126 0.017
regulation of transferase activity GO:0051338 263 0.017
negative regulation of nitric oxide synthase biosynthetic process GO:0051771 1 0.017
regulation of cytokine production GO:0001817 266 0.017
positive regulation of cell death GO:0010942 224 0.017
chemotaxis GO:0006935 247 0.017
male meiosis GO:0007140 37 0.017
response to reactive oxygen species GO:0000302 56 0.017
regulation of protein kinase activity GO:0045859 232 0.017
membrane organization GO:0061024 245 0.017
neuronal action potential GO:0019228 54 0.017
protein modification by small protein conjugation or removal GO:0070647 207 0.017
ribonucleotide metabolic process GO:0009259 291 0.017
apoptotic signaling pathway GO:0097190 306 0.017
carnitine transport GO:0015879 3 0.017
positive regulation of protein phosphorylation GO:0001934 242 0.017
cellular response to hormone stimulus GO:0032870 150 0.016
regulation of mitochondrial fission GO:0090140 3 0.016
gland development GO:0048732 330 0.016
regulation of kinase activity GO:0043549 249 0.016
regulation of hormone levels GO:0010817 211 0.016
cation homeostasis GO:0055080 212 0.016
protein modification by small protein conjugation GO:0032446 187 0.016
fat soluble vitamin biosynthetic process GO:0042362 4 0.016
liver development GO:0001889 66 0.016
regulation of transmembrane transport GO:0034762 128 0.016
homeostasis of number of cells GO:0048872 210 0.016
cellular respiration GO:0045333 38 0.016
cholesterol metabolic process GO:0008203 56 0.016
regulation of lipid metabolic process GO:0019216 118 0.016
hepaticobiliary system development GO:0061008 67 0.016
spermatid differentiation GO:0048515 115 0.016
regulation of cell activation GO:0050865 289 0.016
nucleotide catabolic process GO:0009166 217 0.016
nucleocytoplasmic transport GO:0006913 139 0.016
positive regulation of cellular catabolic process GO:0031331 148 0.016
mapk cascade GO:0000165 281 0.015
meiotic nuclear division GO:0007126 115 0.015
fatty acid derivative metabolic process GO:1901568 33 0.015
skeletal system morphogenesis GO:0048705 203 0.015
ribonucleoside monophosphate metabolic process GO:0009161 80 0.015
glycerolipid metabolic process GO:0046486 122 0.015
regulation of translation GO:0006417 71 0.015
sensory perception GO:0007600 245 0.015
intracellular protein transport GO:0006886 204 0.015
purine ribonucleoside catabolic process GO:0046130 205 0.015
ion transmembrane transport GO:0034220 361 0.015
male gamete generation GO:0048232 285 0.015
maintenance of location GO:0051235 89 0.015
regulation of ion transport GO:0043269 215 0.015
meiotic cell cycle process GO:1903046 77 0.015
limb development GO:0060173 166 0.015
cofactor biosynthetic process GO:0051188 41 0.015
mitotic cell cycle GO:0000278 195 0.015
striated muscle tissue development GO:0014706 293 0.015
monocarboxylic acid catabolic process GO:0072329 27 0.015
cellular response to acid chemical GO:0071229 68 0.015
sterol homeostasis GO:0055092 45 0.015
camera type eye development GO:0043010 266 0.015
protein oligomerization GO:0051259 67 0.014
monocarboxylic acid biosynthetic process GO:0072330 61 0.014
toxin catabolic process GO:0009407 1 0.014
regulation of homeostatic process GO:0032844 182 0.014
synaptic transmission GO:0007268 329 0.014
peptide hormone secretion GO:0030072 109 0.014
sulfur compound biosynthetic process GO:0044272 37 0.014
ribonucleoside catabolic process GO:0042454 206 0.014
locomotory behavior GO:0007626 195 0.014
regulation of protein serine threonine kinase activity GO:0071900 157 0.014
positive regulation of fatty acid oxidation GO:0046321 4 0.014
small gtpase mediated signal transduction GO:0007264 97 0.014
heme metabolic process GO:0042168 16 0.014
leukocyte differentiation GO:0002521 342 0.014
cellular response to lipid GO:0071396 145 0.014
appendage development GO:0048736 166 0.014
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.014
organophosphate biosynthetic process GO:0090407 122 0.014
ras protein signal transduction GO:0007265 77 0.014
skeletal system development GO:0001501 356 0.014
regulation of intracellular transport GO:0032386 159 0.014
negative regulation of organelle organization GO:0010639 90 0.014
cellular chemical homeostasis GO:0055082 215 0.013
regulation of ion transmembrane transport GO:0034765 119 0.013
myeloid cell homeostasis GO:0002262 114 0.013
myeloid cell differentiation GO:0030099 233 0.013
cofactor transport GO:0051181 4 0.013
inorganic cation transmembrane transport GO:0098662 207 0.013
chromatin modification GO:0016568 187 0.013
purine nucleotide catabolic process GO:0006195 211 0.013
cellular response to oxidative stress GO:0034599 76 0.013
establishment of protein localization to organelle GO:0072594 118 0.013
negative regulation of peroxidase activity GO:2000469 1 0.013
organophosphate catabolic process GO:0046434 232 0.013
germ cell development GO:0007281 185 0.013
response to metal ion GO:0010038 47 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.013
regulation of mapk cascade GO:0043408 248 0.013
carbohydrate derivative catabolic process GO:1901136 231 0.013
response to radiation GO:0009314 165 0.013
transmission of nerve impulse GO:0019226 76 0.013
response to peptide hormone GO:0043434 127 0.013
lipid oxidation GO:0034440 29 0.013
cellular response to cytokine stimulus GO:0071345 189 0.013
carbohydrate derivative biosynthetic process GO:1901137 183 0.013
cellular response to molecule of bacterial origin GO:0071219 83 0.013
cellular ion homeostasis GO:0006873 165 0.013
adiponectin activated signaling pathway GO:0033211 4 0.013
regulation of secretion by cell GO:1903530 249 0.012
anion transmembrane transport GO:0098656 71 0.012
developmental growth involved in morphogenesis GO:0060560 138 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.012
regulation of secretion GO:0051046 274 0.012
purine containing compound catabolic process GO:0072523 213 0.012
purine nucleoside monophosphate metabolic process GO:0009126 81 0.012
multicellular organismal homeostasis GO:0048871 164 0.012
ear development GO:0043583 200 0.012
prostaglandin metabolic process GO:0006693 11 0.012
icosanoid metabolic process GO:0006690 33 0.012
negative regulation of mapk cascade GO:0043409 65 0.012
action potential GO:0001508 78 0.012
cellular response to peptide hormone stimulus GO:0071375 92 0.012
spermatid development GO:0007286 108 0.012
folic acid containing compound metabolic process GO:0006760 3 0.012
organic hydroxy compound transport GO:0015850 93 0.012
fatty acid oxidation GO:0019395 28 0.012
cellular response to peptide GO:1901653 92 0.012
cellular protein catabolic process GO:0044257 155 0.012
nucleoside triphosphate catabolic process GO:0009143 205 0.012
purine nucleoside catabolic process GO:0006152 205 0.012
protein maturation GO:0051604 176 0.012
t cell differentiation GO:0030217 174 0.012
modification dependent protein catabolic process GO:0019941 133 0.012
regulation of peptide secretion GO:0002791 77 0.012
cellular metal ion homeostasis GO:0006875 151 0.012
positive regulation of cell development GO:0010720 237 0.012
innate immune response GO:0045087 157 0.012
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902176 4 0.011
lipid modification GO:0030258 65 0.011
nucleoside catabolic process GO:0009164 206 0.011
cellular response to lipopolysaccharide GO:0071222 77 0.011
regulation of cellular response to stress GO:0080135 159 0.011
regulation of monocyte chemotactic protein 1 production GO:0071637 1 0.011
response to insulin GO:0032868 100 0.011
cellular response to cadmium ion GO:0071276 3 0.011
regulation of peptide transport GO:0090087 91 0.011
regulation of protein localization GO:0032880 231 0.011
response to starvation GO:0042594 65 0.011
forebrain development GO:0030900 302 0.011
hexose metabolic process GO:0019318 98 0.011
Human
cellular carbohydrate metabolic process GO:0044262 119 0.011
regulation of binding GO:0051098 111 0.011
response to oxygen levels GO:0070482 62 0.011
cellular alcohol metabolic process GO:0044107 3 0.011
telencephalon development GO:0021537 186 0.011
response to drug GO:0042493 75 0.011
regulation of cell cycle GO:0051726 281 0.011
skin development GO:0043588 220 0.011
amino acid betaine transport GO:0015838 3 0.011
nucleoside monophosphate metabolic process GO:0009123 85 0.011
regulation of fat cell differentiation GO:0045598 81 0.011
reactive nitrogen species metabolic process GO:2001057 0 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.011
regulation of intracellular protein transport GO:0033157 82 0.011
microtubule based process GO:0007017 236 0.011
rna interference GO:0016246 2 0.011
heart morphogenesis GO:0003007 178 0.011
positive regulation of protein kinase activity GO:0045860 144 0.011
regulation of proteolysis GO:0030162 164 0.011
atp metabolic process GO:0046034 75 0.011
ribonucleoside triphosphate catabolic process GO:0009203 199 0.011
purine ribonucleotide catabolic process GO:0009154 208 0.011
positive regulation of binding GO:0051099 49 0.010
negative regulation of chemokine production GO:0032682 4 0.010
actin cytoskeleton organization GO:0030036 220 0.010
response to catecholamine GO:0071869 4 0.010
hematopoietic progenitor cell differentiation GO:0002244 143 0.010
negative regulation of cell proliferation GO:0008285 296 0.010
response to iron ion GO:0010039 4 0.010
cellular response to insulin stimulus GO:0032869 78 0.010
porphyrin containing compound metabolic process GO:0006778 22 0.010
single fertilization GO:0007338 82 0.010
regulation of nucleocytoplasmic transport GO:0046822 73 0.010
urogenital system development GO:0001655 261 0.010
muscle cell differentiation GO:0042692 261 0.010
hormone secretion GO:0046879 128 0.010
covalent chromatin modification GO:0016569 163 0.010
ribonucleotide catabolic process GO:0009261 208 0.010
metal ion homeostasis GO:0055065 189 0.010
metencephalon development GO:0022037 89 0.010
amino acid betaine metabolic process GO:0006577 7 0.010
cellular response to arsenic containing substance GO:0071243 4 0.010
cholesterol homeostasis GO:0042632 44 0.010
carnitine metabolic process GO:0009437 7 0.010
response to testosterone GO:0033574 3 0.010
renal system development GO:0072001 225 0.010
oligopeptide transmembrane transport GO:0035672 4 0.010

Sord disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.049
inherited metabolic disorder DOID:655 0 0.039
amino acid metabolic disorder DOID:9252 0 0.025
nervous system disease DOID:863 0 0.023
disease of anatomical entity DOID:7 0 0.023
disease of cellular proliferation DOID:14566 0 0.018
cancer DOID:162 0 0.017
central nervous system disease DOID:331 0 0.016
sensory system disease DOID:0050155 0 0.015
immune system disease DOID:2914 0 0.014
organ system cancer DOID:0050686 0 0.013
cardiovascular system disease DOID:1287 0 0.013
eye and adnexa disease DOID:1492 0 0.012
retinal disease DOID:5679 0 0.011
retinal degeneration DOID:8466 0 0.011
eye disease DOID:5614 0 0.011