Mus musculus

0 known processes

Ddx46

DEAD (Asp-Glu-Ala-Asp) box polypeptide 46

(Aliases: MGC116676,8430438J23Rik,AI957095,mKIAA0801,2200005K02Rik,MGC31579,AI325430)

Ddx46 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cell cycle process GO:0010564 160 0.503
cellular response to dna damage stimulus GO:0006974 207 0.385
mitotic cell cycle GO:0000278 195 0.375
spermatogenesis GO:0007283 284 0.347
meiotic nuclear division GO:0007126 115 0.340
cellular nitrogen compound catabolic process GO:0044270 280 0.315
Yeast
meiotic cell cycle GO:0051321 122 0.289
protein localization to nucleus GO:0034504 121 0.232
regulation of intracellular transport GO:0032386 159 0.226
regulation of cell cycle GO:0051726 281 0.217
organonitrogen compound catabolic process GO:1901565 264 0.208
Yeast
regulation of cell cycle phase transition GO:1901987 77 0.198
chromosome segregation GO:0007059 48 0.197
mitotic cell cycle process GO:1903047 159 0.174
purine ribonucleotide catabolic process GO:0009154 208 0.173
Yeast
apoptotic signaling pathway GO:0097190 306 0.170
chromatin organization GO:0006325 206 0.166
regulation of organelle organization GO:0033043 289 0.166
protein import into nucleus GO:0006606 95 0.157
protein localization to organelle GO:0033365 185 0.155
organelle fission GO:0048285 170 0.155
organophosphate catabolic process GO:0046434 232 0.148
Yeast
chromatin modification GO:0016568 187 0.147
purine nucleoside triphosphate metabolic process GO:0009144 226 0.147
Yeast
gene silencing by rna GO:0031047 19 0.137
ribose phosphate metabolic process GO:0019693 291 0.134
Yeast
regulation of cell division GO:0051302 76 0.128
regulation of mitotic cell cycle phase transition GO:1901990 73 0.128
membrane organization GO:0061024 245 0.127
organic cyclic compound catabolic process GO:1901361 295 0.123
Yeast
myeloid cell differentiation GO:0030099 233 0.120
regulation of mitotic cell cycle GO:0007346 126 0.115
intrinsic apoptotic signaling pathway GO:0097193 132 0.115
regulation of protein localization GO:0032880 231 0.113
cellular ketone metabolic process GO:0042180 84 0.111
erythrocyte differentiation GO:0030218 88 0.111
ribonucleotide catabolic process GO:0009261 208 0.109
Yeast
histone modification GO:0016570 159 0.105
nucleoside phosphate catabolic process GO:1901292 222 0.102
Yeast
regulation of cellular response to stress GO:0080135 159 0.099
positive regulation of apoptotic process GO:0043065 217 0.097
regulation of protein import into nucleus GO:0042306 52 0.095
mrna metabolic process GO:0016071 84 0.094
Fly
nucleotide metabolic process GO:0009117 332 0.091
Yeast
regulation of apoptotic signaling pathway GO:2001233 197 0.091
purine ribonucleotide metabolic process GO:0009150 290 0.090
Yeast
protein import GO:0017038 101 0.090
homeostasis of number of cells GO:0048872 210 0.089
rna processing GO:0006396 105 0.087
Fly
regulation of dna dependent dna replication GO:0090329 8 0.086
cellular macromolecule catabolic process GO:0044265 206 0.084
aromatic compound catabolic process GO:0019439 286 0.083
Yeast
negative regulation of mitotic cell cycle GO:0045930 58 0.081
cellular amino acid metabolic process GO:0006520 103 0.079
nucleoside catabolic process GO:0009164 206 0.077
Yeast
purine nucleotide catabolic process GO:0006195 211 0.077
Yeast
nuclear import GO:0051170 95 0.077
gene silencing GO:0016458 38 0.075
nuclear division GO:0000280 158 0.071
establishment of protein localization to organelle GO:0072594 118 0.069
ribonucleoside triphosphate metabolic process GO:0009199 220 0.068
Yeast
positive regulation of cell cycle process GO:0090068 61 0.068
regulation of chromosome segregation GO:0051983 21 0.068
regulation of intracellular protein transport GO:0033157 82 0.068
positive regulation of apoptotic signaling pathway GO:2001235 95 0.067
myeloid cell homeostasis GO:0002262 114 0.067
heterocycle catabolic process GO:0046700 280 0.066
Yeast
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.064
regulation of myeloid cell differentiation GO:0045637 96 0.064
nucleobase containing small molecule metabolic process GO:0055086 352 0.061
Yeast
regulation of protein targeting GO:1903533 61 0.060
stem cell differentiation GO:0048863 268 0.060
purine nucleoside catabolic process GO:0006152 205 0.059
Yeast
positive regulation of intracellular transport GO:0032388 70 0.059
protein methylation GO:0006479 81 0.058
single organism nuclear import GO:1902593 95 0.057
positive regulation of programmed cell death GO:0043068 218 0.057
protein targeting GO:0006605 143 0.056
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.056
Yeast
meiotic cell cycle process GO:1903046 77 0.056
nucleotide catabolic process GO:0009166 217 0.055
Yeast
histone lysine methylation GO:0034968 50 0.054
purine containing compound catabolic process GO:0072523 213 0.054
Yeast
purine ribonucleoside catabolic process GO:0046130 205 0.052
Yeast
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.052
rna phosphodiester bond hydrolysis exonucleolytic GO:0090503 4 0.052
response to radiation GO:0009314 165 0.051
regulation of protein transport GO:0051223 163 0.050
nucleoside monophosphate metabolic process GO:0009123 85 0.050
Yeast
stem cell development GO:0048864 219 0.050
intracellular protein transport GO:0006886 204 0.049
macromolecule catabolic process GO:0009057 281 0.049
ribonucleotide metabolic process GO:0009259 291 0.049
Yeast
ribonucleoside metabolic process GO:0009119 245 0.049
Yeast
response to lipopolysaccharide GO:0032496 128 0.047
regulation of cellular amino acid metabolic process GO:0006521 5 0.046
protein modification by small protein conjugation or removal GO:0070647 207 0.046
engulfment of apoptotic cell GO:0043652 3 0.046
regulation of defense response GO:0031347 233 0.045
positive regulation of protein localization to nucleus GO:1900182 30 0.045
positive regulation of intracellular protein transport GO:0090316 42 0.045
glycosyl compound metabolic process GO:1901657 246 0.045
Yeast
purine nucleoside metabolic process GO:0042278 241 0.045
Yeast
covalent chromatin modification GO:0016569 163 0.045
histone methylation GO:0016571 71 0.044
protein processing GO:0016485 163 0.043
immune effector process GO:0002252 321 0.043
atp catabolic process GO:0006200 55 0.043
Yeast
regulation of protein localization to nucleus GO:1900180 60 0.042
heterochromatin organization GO:0070828 4 0.042
mrna 3 end processing GO:0031124 16 0.042
cell division GO:0051301 120 0.042
male meiosis GO:0007140 37 0.042
cellular amine metabolic process GO:0044106 44 0.042
ribonucleoside monophosphate metabolic process GO:0009161 80 0.041
Yeast
regulation of establishment of protein localization GO:0070201 181 0.041
purine nucleotide metabolic process GO:0006163 302 0.041
Yeast
axonogenesis GO:0007409 274 0.040
histone h3 k4 methylation GO:0051568 23 0.040
regulation of protein complex assembly GO:0043254 83 0.040
regulation of homeostatic process GO:0032844 182 0.039
osmosensory signaling pathway GO:0007231 1 0.039
regulation of transcription by chromatin organization GO:0034401 0 0.039
mitotic nuclear division GO:0007067 48 0.039
purine ribonucleoside metabolic process GO:0046128 241 0.039
Yeast
telomere maintenance GO:0000723 19 0.038
organelle localization GO:0051640 179 0.038
inositol phosphate catabolic process GO:0071545 4 0.038
positive regulation of chromosome segregation GO:0051984 4 0.038
ribonucleoside catabolic process GO:0042454 206 0.037
Yeast
organic hydroxy compound metabolic process GO:1901615 203 0.037
neuronal action potential GO:0019228 54 0.037
cellular protein catabolic process GO:0044257 155 0.037
posttranscriptional gene silencing GO:0016441 10 0.036
nucleoside triphosphate metabolic process GO:0009141 230 0.036
Yeast
protein modification by small protein removal GO:0070646 21 0.036
positive regulation of chromosome organization GO:2001252 33 0.036
positive regulation of innate immune response GO:0045089 80 0.036
ribonucleoside triphosphate catabolic process GO:0009203 199 0.036
Yeast
negative regulation of molecular function GO:0044092 258 0.035
glycerolipid metabolic process GO:0046486 122 0.035
positive regulation of cell death GO:0010942 224 0.035
rna catabolic process GO:0006401 29 0.035
regulation of cellular catabolic process GO:0031329 242 0.034
regulation of cytoplasmic transport GO:1903649 112 0.034
male gamete generation GO:0048232 285 0.034
response to light stimulus GO:0009416 135 0.034
cellular response to inorganic substance GO:0071241 37 0.033
signal transduction by p53 class mediator GO:0072331 51 0.033
development of primary sexual characteristics GO:0045137 143 0.033
carbohydrate derivative catabolic process GO:1901136 231 0.032
Yeast
purine nucleoside triphosphate catabolic process GO:0009146 203 0.032
Yeast
positive regulation of defense response GO:0031349 124 0.032
nucleoside phosphate metabolic process GO:0006753 338 0.032
Yeast
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.032
Yeast
cellular response to radiation GO:0071478 28 0.032
mitotic sister chromatid segregation GO:0000070 14 0.031
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.031
Yeast
positive regulation of dna templated transcription initiation GO:2000144 5 0.031
regionalization GO:0003002 337 0.031
regulation of cellular component biogenesis GO:0044087 181 0.030
regulation of nuclear division GO:0051783 56 0.030
regulation of nucleocytoplasmic transport GO:0046822 73 0.030
organelle assembly GO:0070925 177 0.030
positive regulation of nfat protein import into nucleus GO:0051533 1 0.030
male meiosis i GO:0007141 16 0.030
action potential GO:0001508 78 0.030
regulation of system process GO:0044057 200 0.029
cell cycle checkpoint GO:0000075 47 0.029
amine metabolic process GO:0009308 45 0.029
regulation of transcription during meiosis GO:0051037 1 0.028
nucleoside triphosphate catabolic process GO:0009143 205 0.028
Yeast
lipid localization GO:0010876 126 0.028
spliceosomal complex disassembly GO:0000390 1 0.028
regulation of nuclear cell cycle dna replication GO:0033262 2 0.028
dna dependent dna replication maintenance of fidelity GO:0045005 3 0.028
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.028
leukocyte differentiation GO:0002521 342 0.028
negative regulation of cell cycle GO:0045786 123 0.028
dna metabolic process GO:0006259 303 0.028
glycosyl compound catabolic process GO:1901658 206 0.028
Yeast
protein maturation GO:0051604 176 0.028
negative regulation of immune system process GO:0002683 209 0.028
blastocyst development GO:0001824 80 0.027
regulation of chromosome organization GO:0033044 83 0.027
dna repair GO:0006281 107 0.027
negative regulation of protein metabolic process GO:0051248 282 0.027
regulation of mrna metabolic process GO:1903311 43 0.026
Fly
regulation of protein processing GO:0070613 96 0.026
oocyte development GO:0048599 33 0.026
positive regulation of cellular amine metabolic process GO:0033240 5 0.026
macromolecule methylation GO:0043414 120 0.026
methylation GO:0032259 134 0.026
posttranscriptional regulation of gene expression GO:0010608 155 0.026
multicellular organismal signaling GO:0035637 91 0.026
protein modification by small protein conjugation GO:0032446 187 0.026
hindbrain development GO:0030902 128 0.026
dendrite development GO:0016358 115 0.026
ossification GO:0001503 216 0.025
rna splicing GO:0008380 54 0.025
Fly
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 3 0.025
nucleus organization GO:0006997 45 0.025
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.025
Yeast
positive regulation of organelle organization GO:0010638 128 0.025
muscle tissue development GO:0060537 308 0.025
rna interference GO:0016246 2 0.025
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.025
protein alkylation GO:0008213 81 0.025
response to uv GO:0009411 44 0.024
histone h3 k36 methylation GO:0010452 6 0.024
negative regulation of dna replication GO:0008156 4 0.024
protein localization to membrane GO:0072657 108 0.024
compound eye development GO:0048749 1 0.024
negative regulation of cell cycle phase transition GO:1901988 48 0.024
negative regulation of protein processing GO:0010955 79 0.024
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.023
blastocyst growth GO:0001832 23 0.023
regulation of proteolysis GO:0030162 164 0.023
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 2 0.023
positive regulation of protein complex assembly GO:0031334 45 0.023
modification dependent protein catabolic process GO:0019941 133 0.023
response to molecule of bacterial origin GO:0002237 143 0.023
rna 3 end processing GO:0031123 20 0.023
protein catabolic process GO:0030163 221 0.023
maintenance of location GO:0051235 89 0.023
lateral inhibition GO:0046331 1 0.022
nucleoside monophosphate catabolic process GO:0009125 59 0.022
Yeast
purine containing compound metabolic process GO:0072521 311 0.022
Yeast
meiotic chromosome segregation GO:0045132 19 0.022
regulation of engulfment of apoptotic cell GO:1901074 2 0.021
myeloid leukocyte differentiation GO:0002573 119 0.021
regulation of binding GO:0051098 111 0.021
negative regulation of protein maturation GO:1903318 79 0.021
double strand break repair GO:0006302 48 0.021
dna damage checkpoint GO:0000077 26 0.021
peptidyl amino acid modification GO:0018193 336 0.021
regulation of cellular amine metabolic process GO:0033238 20 0.020
response to inorganic substance GO:0010035 96 0.020
cellular response to molecule of bacterial origin GO:0071219 83 0.020
chromatin silencing GO:0006342 15 0.020
cytoplasmic transport GO:0016482 234 0.020
nucleocytoplasmic transport GO:0006913 139 0.020
purine nucleoside monophosphate catabolic process GO:0009128 58 0.020
Yeast
regulation of response to dna damage stimulus GO:2001020 34 0.020
regulation of meiotic cell cycle GO:0051445 34 0.020
regulation of cellular ketone metabolic process GO:0010565 66 0.020
dna damage response signal transduction by p53 class mediator GO:0030330 19 0.020
oocyte axis specification GO:0007309 2 0.020
negative regulation of cellular protein metabolic process GO:0032269 247 0.020
regulation of response to wounding GO:1903034 189 0.019
g2 dna damage checkpoint GO:0031572 8 0.019
regulation of innate immune response GO:0045088 91 0.019
regulation of mitotic sister chromatid segregation GO:0033047 12 0.019
b cell activation GO:0042113 161 0.019
cellular homeostasis GO:0019725 240 0.019
regulation of dna replication GO:0006275 17 0.019
response to organonitrogen compound GO:0010243 246 0.019
dna dependent dna replication GO:0006261 24 0.019
negative regulation of cellular component organization GO:0051129 194 0.018
myelination GO:0042552 74 0.018
positive regulation of protein transport GO:0051222 93 0.018
multicellular organism growth GO:0035264 161 0.018
purine nucleoside monophosphate metabolic process GO:0009126 81 0.018
Yeast
regulation of cell activation GO:0050865 289 0.018
phosphatidylinositol metabolic process GO:0046488 45 0.018
regulation of cell motility GO:2000145 236 0.018
positive regulation of cell cycle GO:0045787 92 0.018
dna endoreduplication GO:0042023 4 0.017
signal transduction in response to dna damage GO:0042770 21 0.017
striated muscle tissue development GO:0014706 293 0.017
dna integrity checkpoint GO:0031570 28 0.017
morphogenesis of embryonic epithelium GO:0016331 159 0.017
proteasomal protein catabolic process GO:0010498 98 0.017
chromatin silencing at rdna GO:0000183 3 0.017
nuclear transport GO:0051169 139 0.017
meiosis i GO:0007127 60 0.017
modification dependent macromolecule catabolic process GO:0043632 133 0.017
nuclear membrane organization GO:0071763 4 0.017
nucleoside metabolic process GO:0009116 246 0.017
Yeast
negative regulation of toll signaling pathway GO:0045751 1 0.017
nuclear transcribed mrna catabolic process deadenylation dependent decay GO:0000288 12 0.016
regulation of vesicle mediated transport GO:0060627 139 0.016
anatomical structure homeostasis GO:0060249 145 0.016
cellular response to growth factor stimulus GO:0071363 197 0.016
heterochromatin organization involved in chromatin silencing GO:0070868 1 0.016
peptidyl serine phosphorylation GO:0018105 74 0.016
peptidyl lysine modification GO:0018205 77 0.016
positive regulation of homeostatic process GO:0032846 64 0.016
oocyte anterior posterior axis specification GO:0007314 2 0.016
positive regulation of protein modification process GO:0031401 299 0.016
negative regulation of defense response GO:0031348 77 0.016
dna replication GO:0006260 52 0.016
negative regulation of intracellular signal transduction GO:1902532 167 0.016
positive regulation of cytoplasmic transport GO:1903651 40 0.016
positive regulation of mitotic cell cycle GO:0045931 41 0.015
amp metabolic process GO:0046033 4 0.015
regulation of protein maturation GO:1903317 96 0.015
heterochromatin maintenance GO:0070829 1 0.015
regulation of secretion GO:0051046 274 0.015
positive regulation of intrinsic apoptotic signaling pathway GO:2001244 25 0.015
lymphocyte differentiation GO:0030098 242 0.015
cellular response to lipid GO:0071396 145 0.015
developmental maturation GO:0021700 193 0.015
protein desumoylation GO:0016926 2 0.015
ubiquitin dependent protein catabolic process GO:0006511 129 0.015
regulation of toll signaling pathway GO:0008592 1 0.014
response to organic cyclic compound GO:0014070 198 0.014
cellular response to sterol GO:0036315 2 0.014
regulation of inflammatory response GO:0050727 147 0.014
regulation of hormone levels GO:0010817 211 0.014
cell cycle switching GO:0060184 1 0.014
maternal determination of anterior posterior axis embryo GO:0008358 2 0.014
regulation of membrane potential GO:0042391 192 0.014
regulation of transcription factor import into nucleus GO:0042990 24 0.014
signal transduction involved in mitotic dna integrity checkpoint GO:1902403 3 0.014
cell cycle switching mitotic to meiotic cell cycle GO:0051728 1 0.014
regulation of histone h3 k36 methylation GO:0000414 1 0.014
cardiac muscle tissue development GO:0048738 130 0.013
defense response to bacterium GO:0042742 119 0.013
cytokine production GO:0001816 319 0.013
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.013
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.013
negative regulation of cellular catabolic process GO:0031330 47 0.013
negative regulation of organelle organization GO:0010639 90 0.013
regulation of chromatin organization GO:1902275 57 0.013
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.013
inflammatory response GO:0006954 244 0.013
circulatory system process GO:0003013 197 0.013
positive regulation of protein import into nucleus GO:0042307 26 0.013
adult behavior GO:0030534 135 0.013
regulation of erythrocyte differentiation GO:0045646 23 0.013
intracellular mrna localization GO:0008298 4 0.013
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.013
atp metabolic process GO:0046034 75 0.013
Yeast
bone development GO:0060348 120 0.013
skeletal system development GO:0001501 356 0.013
dna templated transcriptional preinitiation complex assembly GO:0070897 4 0.013
cellular chemical homeostasis GO:0055082 215 0.012
negative regulation of cell proliferation GO:0008285 296 0.012
chromosome condensation GO:0030261 10 0.012
response to amino acid GO:0043200 37 0.012
peptide metabolic process GO:0006518 46 0.012
calcium ion homeostasis GO:0055074 127 0.012
leukocyte proliferation GO:0070661 172 0.012
dephosphorylation GO:0016311 129 0.012
vesicle localization GO:0051648 86 0.012
vacuole organization GO:0007033 38 0.012
nuclear dna replication GO:0033260 3 0.012
glucose homeostasis GO:0042593 128 0.012
female gamete generation GO:0007292 74 0.012
regulation of cytokine production GO:0001817 266 0.012
placenta development GO:0001890 140 0.012
microtubule cytoskeleton organization GO:0000226 157 0.012
axon ensheathment GO:0008366 76 0.012
response to extracellular stimulus GO:0009991 127 0.012
dna replication independent nucleosome assembly GO:0006336 1 0.012
cellular response to gamma radiation GO:0071480 4 0.012
germline cell cycle switching mitotic to meiotic cell cycle GO:0051729 1 0.012
maintenance of protein location in nucleus GO:0051457 2 0.012
neuron projection extension GO:1990138 64 0.012
gtp catabolic process GO:0006184 143 0.012
transmission of nerve impulse GO:0019226 76 0.012
regulation of histone methylation GO:0031060 30 0.011
cellular response to lipopolysaccharide GO:0071222 77 0.011
establishment of vesicle localization GO:0051650 81 0.011
sister chromatid segregation GO:0000819 20 0.011
response to heat GO:0009408 27 0.011
ensheathment of neurons GO:0007272 76 0.011
cellular response to cytokine stimulus GO:0071345 189 0.011
germ cell development GO:0007281 185 0.011
synaptic transmission GO:0007268 329 0.011
regulation of lymphocyte activation GO:0051249 240 0.011
gonad development GO:0008406 141 0.011
protein tetramerization GO:0051262 23 0.011
positive regulation of nervous system development GO:0051962 221 0.011
mitotic cell cycle checkpoint GO:0007093 31 0.011
response to sterol GO:0036314 4 0.011
striated muscle contraction GO:0006941 45 0.011
muscle contraction GO:0006936 101 0.011
male meiosis chromosome segregation GO:0007060 3 0.011
stem cell maintenance GO:0019827 130 0.010
negative regulation of protein modification process GO:0031400 163 0.010
cell growth GO:0016049 130 0.010
carbohydrate metabolic process GO:0005975 230 0.010
nuclear transcribed mrna poly a tail shortening GO:0000289 7 0.010
gliogenesis GO:0042063 141 0.010
regulation of chromatin modification GO:1903308 57 0.010

Ddx46 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.060
nervous system disease DOID:863 0 0.060
retinal disease DOID:5679 0 0.036
sensory system disease DOID:0050155 0 0.036
eye and adnexa disease DOID:1492 0 0.036
eye disease DOID:5614 0 0.036
retinal degeneration DOID:8466 0 0.027
central nervous system disease DOID:331 0 0.020
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013