Mus musculus

0 known processes

Setd8

SET domain containing (lysine methyltransferase) 8

(Aliases: AA617402,MGC117832,AW536475,2410195B05Rik,PR-SET7)

Setd8 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of molecular function GO:0044092 258 0.138
dna metabolic process GO:0006259 303 0.101
Fly
regulation of cellular catabolic process GO:0031329 242 0.100
cellular amine metabolic process GO:0044106 44 0.093
cellular amino acid metabolic process GO:0006520 103 0.092
apoptotic signaling pathway GO:0097190 306 0.087
protein catabolic process GO:0030163 221 0.083
mitochondrion organization GO:0007005 134 0.083
amine metabolic process GO:0009308 45 0.081
striated muscle tissue development GO:0014706 293 0.076
cation transport GO:0006812 399 0.075
negative regulation of cell proliferation GO:0008285 296 0.074
transmembrane transport GO:0055085 412 0.071
regulation of cellular amine metabolic process GO:0033238 20 0.068
negative regulation of phosphate metabolic process GO:0045936 184 0.066
positive regulation of cellular amine metabolic process GO:0033240 5 0.064
spermatogenesis GO:0007283 284 0.063
male gamete generation GO:0048232 285 0.062
response to oxidative stress GO:0006979 123 0.060
peptidyl amino acid modification GO:0018193 336 0.058
Human Fly
cytoplasmic transport GO:0016482 234 0.057
carbohydrate metabolic process GO:0005975 230 0.056
positive regulation of cellular catabolic process GO:0031331 148 0.056
regulation of kinase activity GO:0043549 249 0.056
negative regulation of cellular amine metabolic process GO:0033239 1 0.055
regulation of cell cycle GO:0051726 281 0.053
muscle tissue development GO:0060537 308 0.053
nucleobase containing small molecule metabolic process GO:0055086 352 0.052
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.052
regulation of protein kinase activity GO:0045859 232 0.051
positive regulation of programmed cell death GO:0043068 218 0.049
protein maturation GO:0051604 176 0.049
cellular protein catabolic process GO:0044257 155 0.048
translation GO:0006412 93 0.048
regulation of hydrolase activity GO:0051336 246 0.048
positive regulation of protein modification process GO:0031401 299 0.047
negative regulation of phosphorus metabolic process GO:0010563 184 0.046
cellular ketone metabolic process GO:0042180 84 0.046
regulation of cell cycle process GO:0010564 160 0.045
positive regulation of cell death GO:0010942 224 0.044
regulation of cellular amino acid metabolic process GO:0006521 5 0.044
regulation of binding GO:0051098 111 0.043
mitotic cell cycle GO:0000278 195 0.043
development of primary male sexual characteristics GO:0046546 88 0.042
negative regulation of cellular protein metabolic process GO:0032269 247 0.042
oxidation reduction process GO:0055114 342 0.042
organonitrogen compound biosynthetic process GO:1901566 192 0.042
regulation of proteolysis GO:0030162 164 0.042
skeletal muscle organ development GO:0060538 163 0.042
wnt signaling pathway GO:0016055 188 0.042
cellular lipid metabolic process GO:0044255 323 0.041
negative regulation of protein metabolic process GO:0051248 282 0.041
positive regulation of apoptotic process GO:0043065 217 0.040
regulation of protein localization GO:0032880 231 0.040
stem cell differentiation GO:0048863 268 0.040
g1 s transition of mitotic cell cycle GO:0000082 57 0.039
regulation of cellular ketone metabolic process GO:0010565 66 0.039
small gtpase mediated signal transduction GO:0007264 97 0.039
nucleotide metabolic process GO:0009117 332 0.039
proteasomal protein catabolic process GO:0010498 98 0.039
regulation of apoptotic signaling pathway GO:2001233 197 0.038
ion transmembrane transport GO:0034220 361 0.038
negative regulation of intracellular signal transduction GO:1902532 167 0.038
actin cytoskeleton organization GO:0030036 220 0.038
positive regulation of protein phosphorylation GO:0001934 242 0.038
leukocyte differentiation GO:0002521 342 0.038
dephosphorylation GO:0016311 129 0.038
regulation of organelle organization GO:0033043 289 0.037
germ cell development GO:0007281 185 0.036
muscle cell differentiation GO:0042692 261 0.036
multicellular organism growth GO:0035264 161 0.036
positive regulation of mitochondrion organization GO:0010822 17 0.035
regulation of protein serine threonine kinase activity GO:0071900 157 0.035
nucleoside phosphate metabolic process GO:0006753 338 0.035
ras protein signal transduction GO:0007265 77 0.035
transmission of nerve impulse GO:0019226 76 0.035
mitotic cell cycle process GO:1903047 159 0.035
microtubule based process GO:0007017 236 0.035
purine nucleoside metabolic process GO:0042278 241 0.034
response to organonitrogen compound GO:0010243 246 0.034
regulation of ion transport GO:0043269 215 0.033
regulation of muscle tissue development GO:1901861 97 0.033
membrane organization GO:0061024 245 0.033
protein modification by small protein conjugation or removal GO:0070647 207 0.033
carbohydrate derivative biosynthetic process GO:1901137 183 0.033
negative regulation of phosphorylation GO:0042326 166 0.032
cellular homeostasis GO:0019725 240 0.032
cytokine production GO:0001816 319 0.031
response to organic cyclic compound GO:0014070 198 0.031
protein localization to nucleus GO:0034504 121 0.031
regulation of protein catabolic process GO:0042176 108 0.030
regulation of cytokine production GO:0001817 266 0.029
chromatin organization GO:0006325 206 0.029
Human Fly
regulation of transferase activity GO:0051338 263 0.029
stem cell development GO:0048864 219 0.029
glycosyl compound metabolic process GO:1901657 246 0.029
modification dependent macromolecule catabolic process GO:0043632 133 0.029
signal transduction by p53 class mediator GO:0072331 51 0.029
Human
regulation of cell migration GO:0030334 219 0.028
protein localization to organelle GO:0033365 185 0.028
negative regulation of apoptotic signaling pathway GO:2001234 104 0.028
cellular response to gamma radiation GO:0071480 4 0.028
organelle fission GO:0048285 170 0.028
digestive system development GO:0055123 200 0.028
protein ubiquitination GO:0016567 171 0.028
skeletal system development GO:0001501 356 0.028
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.027
urogenital system development GO:0001655 261 0.027
positive regulation of proteolysis GO:0045862 85 0.027
spermatid differentiation GO:0048515 115 0.027
nitrogen compound transport GO:0071705 271 0.027
synaptic transmission GO:0007268 329 0.027
regulation of mapk cascade GO:0043408 248 0.027
organophosphate catabolic process GO:0046434 232 0.027
intrinsic apoptotic signaling pathway GO:0097193 132 0.027
compound eye development GO:0048749 1 0.027
regulation of translation GO:0006417 71 0.026
lymphocyte differentiation GO:0030098 242 0.026
protein processing GO:0016485 163 0.026
nucleocytoplasmic transport GO:0006913 139 0.026
macromolecule catabolic process GO:0009057 281 0.026
purine nucleotide metabolic process GO:0006163 302 0.026
positive regulation of organelle organization GO:0010638 128 0.026
muscle cell development GO:0055001 133 0.026
purine ribonucleotide metabolic process GO:0009150 290 0.026
regulation of mitotic cell cycle GO:0007346 126 0.026
meiotic cell cycle GO:0051321 122 0.025
regulation of striated muscle cell differentiation GO:0051153 81 0.025
myeloid cell homeostasis GO:0002262 114 0.025
action potential GO:0001508 78 0.025
positive regulation of hydrolase activity GO:0051345 148 0.025
cell type specific apoptotic process GO:0097285 268 0.025
developmental maturation GO:0021700 193 0.025
lateral inhibition GO:0046331 1 0.025
epithelial tube morphogenesis GO:0060562 303 0.025
regulation of epithelial cell proliferation GO:0050678 141 0.025
morphogenesis of a branching epithelium GO:0061138 193 0.025
lipid biosynthetic process GO:0008610 179 0.025
cellular protein complex assembly GO:0043623 116 0.025
cellular carbohydrate metabolic process GO:0044262 119 0.025
organic cyclic compound catabolic process GO:1901361 295 0.024
regulation of peptidase activity GO:0052547 96 0.024
connective tissue development GO:0061448 179 0.024
multicellular organismal signaling GO:0035637 91 0.024
protein targeting GO:0006605 143 0.024
cellular response to dna damage stimulus GO:0006974 207 0.024
Human Fly
cellular ion homeostasis GO:0006873 165 0.024
generation of precursor metabolites and energy GO:0006091 103 0.024
ribose phosphate metabolic process GO:0019693 291 0.024
intracellular protein transport GO:0006886 204 0.024
forebrain development GO:0030900 302 0.024
gonad development GO:0008406 141 0.024
negative regulation of cell cycle GO:0045786 123 0.024
myeloid cell differentiation GO:0030099 233 0.023
reactive oxygen species metabolic process GO:0072593 84 0.023
organonitrogen compound catabolic process GO:1901565 264 0.023
myeloid leukocyte differentiation GO:0002573 119 0.023
neuronal action potential GO:0019228 54 0.023
homeostasis of number of cells GO:0048872 210 0.023
development of primary sexual characteristics GO:0045137 143 0.023
extrinsic apoptotic signaling pathway GO:0097191 126 0.023
gland development GO:0048732 330 0.023
neuron death GO:0070997 154 0.023
posttranscriptional regulation of gene expression GO:0010608 155 0.023
regionalization GO:0003002 337 0.023
Zebrafish
divalent metal ion transport GO:0070838 172 0.023
positive regulation of peptidase activity GO:0010952 49 0.023
heterocycle catabolic process GO:0046700 280 0.023
response to radiation GO:0009314 165 0.023
regulation of endopeptidase activity GO:0052548 89 0.023
divalent inorganic cation transport GO:0072511 178 0.022
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.022
organic hydroxy compound metabolic process GO:1901615 203 0.022
regulation of secretion GO:0051046 274 0.022
mapk cascade GO:0000165 281 0.022
epithelial cell proliferation GO:0050673 174 0.022
g protein coupled receptor signaling pathway GO:0007186 243 0.022
modification dependent protein catabolic process GO:0019941 133 0.022
cellular response to organonitrogen compound GO:0071417 145 0.022
purine containing compound metabolic process GO:0072521 311 0.022
response to molecule of bacterial origin GO:0002237 143 0.022
organ growth GO:0035265 117 0.022
positive regulation of kinase activity GO:0033674 155 0.022
organic anion transport GO:0015711 137 0.022
spermatid development GO:0007286 108 0.022
placenta development GO:0001890 140 0.022
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.022
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.021
purine ribonucleoside metabolic process GO:0046128 241 0.021
regulation of cell cycle phase transition GO:1901987 77 0.021
purine ribonucleoside catabolic process GO:0046130 205 0.021
cellular amide metabolic process GO:0043603 58 0.021
small molecule biosynthetic process GO:0044283 132 0.021
regulation of proteasomal protein catabolic process GO:0061136 46 0.021
regulation of cell motility GO:2000145 236 0.021
maintenance of location GO:0051235 89 0.021
chromatin modification GO:0016568 187 0.021
Human Fly
negative regulation of protein modification process GO:0031400 163 0.021
regulation of purine nucleotide metabolic process GO:1900542 169 0.021
positive regulation of endopeptidase activity GO:0010950 43 0.021
nucleoside triphosphate catabolic process GO:0009143 205 0.021
nucleoside triphosphate metabolic process GO:0009141 230 0.021
cation homeostasis GO:0055080 212 0.021
regulation of wnt signaling pathway GO:0030111 123 0.021
anion transport GO:0006820 177 0.021
sensory perception GO:0007600 245 0.020
negative regulation of mitotic cell cycle GO:0045930 58 0.020
purine ribonucleotide catabolic process GO:0009154 208 0.020
male sex differentiation GO:0046661 109 0.020
regulation of defense response GO:0031347 233 0.020
negative regulation of neuron death GO:1901215 98 0.020
protein import into nucleus GO:0006606 95 0.020
regulation of neuron death GO:1901214 134 0.020
cellular nitrogen compound catabolic process GO:0044270 280 0.020
cell cycle g1 s phase transition GO:0044843 57 0.020
cofactor metabolic process GO:0051186 80 0.020
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.020
myosin filament assembly GO:0031034 2 0.020
single organism nuclear import GO:1902593 95 0.020
anion transmembrane transport GO:0098656 71 0.020
inflammatory response GO:0006954 244 0.020
respiratory tube development GO:0030323 167 0.020
ossification GO:0001503 216 0.020
purine nucleotide catabolic process GO:0006195 211 0.020
chromosome segregation GO:0007059 48 0.020
positive regulation of cell development GO:0010720 237 0.020
regulation of cellular component size GO:0032535 121 0.020
multicellular organismal homeostasis GO:0048871 164 0.020
regulation of secretion by cell GO:1903530 249 0.020
regulation of protein transport GO:0051223 163 0.019
regulation of mitochondrion organization GO:0010821 27 0.019
chemotaxis GO:0006935 247 0.019
negative regulation of cellular component organization GO:0051129 194 0.019
nucleoside phosphate catabolic process GO:1901292 222 0.019
ribonucleoside metabolic process GO:0009119 245 0.019
regulation of membrane potential GO:0042391 192 0.019
methylation GO:0032259 134 0.019
Human Fly
cell adhesion GO:0007155 329 0.019
ribonucleoside triphosphate metabolic process GO:0009199 220 0.019
positive regulation of cell cycle GO:0045787 92 0.019
regulation of homeostatic process GO:0032844 182 0.019
response to peptide GO:1901652 136 0.019
response to lipopolysaccharide GO:0032496 128 0.019
regulation of metal ion transport GO:0010959 106 0.019
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.019
calcium ion transport GO:0006816 159 0.019
nuclear import GO:0051170 95 0.019
meiosis i GO:0007127 60 0.019
canonical wnt signaling pathway GO:0060070 130 0.019
response to inorganic substance GO:0010035 96 0.019
energy derivation by oxidation of organic compounds GO:0015980 77 0.018
myosin filament organization GO:0031033 3 0.018
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.018
striated muscle cell development GO:0055002 125 0.018
purine nucleoside triphosphate catabolic process GO:0009146 203 0.018
ribonucleotide catabolic process GO:0009261 208 0.018
regulation of cytoplasmic transport GO:1903649 112 0.018
carbohydrate derivative catabolic process GO:1901136 231 0.018
meiotic nuclear division GO:0007126 115 0.018
anatomical structure homeostasis GO:0060249 145 0.018
regulation of hormone levels GO:0010817 211 0.018
regulation of ion transmembrane transport GO:0034765 119 0.018
epithelial cell development GO:0002064 159 0.018
skeletal system morphogenesis GO:0048705 203 0.018
morphogenesis of a branching structure GO:0001763 203 0.018
regulation of system process GO:0044057 200 0.018
nucleotide catabolic process GO:0009166 217 0.018
cellular response to acid chemical GO:0071229 68 0.018
endomembrane system organization GO:0010256 147 0.018
organic acid transport GO:0015849 101 0.018
cellular response to hormone stimulus GO:0032870 150 0.018
telencephalon development GO:0021537 186 0.018
sensory organ morphogenesis GO:0090596 242 0.018
adult behavior GO:0030534 135 0.018
sequestering of calcium ion GO:0051208 18 0.018
ribonucleoside catabolic process GO:0042454 206 0.018
regulation of cellular protein catabolic process GO:1903362 61 0.018
glucose homeostasis GO:0042593 128 0.018
positive regulation of transferase activity GO:0051347 167 0.018
response to light stimulus GO:0009416 135 0.018
regulation of intracellular transport GO:0032386 159 0.018
regulation of cellular component biogenesis GO:0044087 181 0.018
aromatic compound catabolic process GO:0019439 286 0.018
cell maturation GO:0048469 127 0.018
locomotory behavior GO:0007626 195 0.018
negative regulation of transferase activity GO:0051348 85 0.018
immune effector process GO:0002252 321 0.018
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.018
regulation of actin filament based process GO:0032970 99 0.017
cellular response to growth factor stimulus GO:0071363 197 0.017
multi multicellular organism process GO:0044706 109 0.017
positive regulation of protein kinase activity GO:0045860 144 0.017
mitochondrial membrane organization GO:0007006 26 0.017
regulation of establishment of protein localization GO:0070201 181 0.017
amide transport GO:0042886 138 0.017
male gonad development GO:0008584 88 0.017
carbohydrate homeostasis GO:0033500 128 0.017
glycosyl compound catabolic process GO:1901658 206 0.017
regulation of reactive oxygen species metabolic process GO:2000377 40 0.017
antimicrobial peptide biosynthetic process GO:0002777 2 0.017
tissue homeostasis GO:0001894 115 0.017
t cell activation GO:0042110 289 0.017
cell cycle checkpoint GO:0000075 47 0.017
Fly
establishment of protein localization to organelle GO:0072594 118 0.017
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.017
branching morphogenesis of an epithelial tube GO:0048754 159 0.017
nucleoside metabolic process GO:0009116 246 0.017
sequestering of metal ion GO:0051238 19 0.017
regulation of nucleoside metabolic process GO:0009118 130 0.017
negative regulation of cell cycle process GO:0010948 69 0.017
regulation of anatomical structure size GO:0090066 178 0.017
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.017
hematopoietic progenitor cell differentiation GO:0002244 143 0.017
ubiquitin dependent protein catabolic process GO:0006511 129 0.017
cell growth GO:0016049 130 0.017
rhythmic process GO:0048511 174 0.016
apoptotic mitochondrial changes GO:0008637 48 0.016
mitochondrial transport GO:0006839 36 0.016
regulation of cellular response to stress GO:0080135 159 0.016
Human
cell fate commitment GO:0045165 210 0.016
citrate metabolic process GO:0006101 3 0.016
ribonucleotide metabolic process GO:0009259 291 0.016
actin filament organization GO:0007015 113 0.016
nuclear transport GO:0051169 139 0.016
response to temperature stimulus GO:0009266 55 0.016
respiratory system development GO:0060541 190 0.016
regulation of mitotic cell cycle phase transition GO:1901990 73 0.016
regulation of chromosome organization GO:0033044 83 0.016
fat cell differentiation GO:0045444 160 0.016
blood circulation GO:0008015 195 0.016
response to oxygen levels GO:0070482 62 0.016
regulation of organ morphogenesis GO:2000027 144 0.016
nucleoside catabolic process GO:0009164 206 0.016
organophosphate biosynthetic process GO:0090407 122 0.016
positive regulation of apoptotic signaling pathway GO:2001235 95 0.016
striated muscle myosin thick filament assembly GO:0071688 1 0.016
monocarboxylic acid metabolic process GO:0032787 191 0.016
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.016
stem cell maintenance GO:0019827 130 0.016
regulation of phospholipid biosynthetic process GO:0071071 3 0.016
hexose metabolic process GO:0019318 98 0.016
positive regulation of nucleotide metabolic process GO:0045981 114 0.016
neuron apoptotic process GO:0051402 142 0.016
negative regulation of nervous system development GO:0051961 156 0.016
embryonic organ morphogenesis GO:0048562 276 0.016
cellular macromolecule catabolic process GO:0044265 206 0.016
organelle assembly GO:0070925 177 0.016
ameboidal type cell migration GO:0001667 128 0.016
skin development GO:0043588 220 0.016
negative regulation of cell development GO:0010721 169 0.016
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.016
purine nucleoside catabolic process GO:0006152 205 0.016
positive regulation of nucleotide catabolic process GO:0030813 88 0.015
glycerolipid metabolic process GO:0046486 122 0.015
response to acid chemical GO:0001101 111 0.015
protein import GO:0017038 101 0.015
cell cycle switching GO:0060184 1 0.015
muscle system process GO:0003012 141 0.015
female gamete generation GO:0007292 74 0.015
meiotic cell cycle process GO:1903046 77 0.015
single organism cell adhesion GO:0098602 156 0.015
t cell differentiation GO:0030217 174 0.015
organelle localization GO:0051640 179 0.015
sulfur compound metabolic process GO:0006790 100 0.015
cellular component assembly involved in morphogenesis GO:0010927 139 0.015
positive regulation of gtpase activity GO:0043547 85 0.015
regulation of neuron apoptotic process GO:0043523 122 0.015
epidermis development GO:0008544 187 0.015
glycoprotein metabolic process GO:0009100 116 0.015
male meiosis GO:0007140 37 0.015
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.014
b cell activation GO:0042113 161 0.014
regulation of nucleotide metabolic process GO:0006140 169 0.014
developmental growth involved in morphogenesis GO:0060560 138 0.014
photoreceptor cell differentiation GO:0046530 52 0.014
cellular divalent inorganic cation homeostasis GO:0072503 127 0.014
negative regulation of protein maturation GO:1903318 79 0.014
digestive tract morphogenesis GO:0048546 147 0.014
negative regulation of protein phosphorylation GO:0001933 126 0.014
regulation of phosphatidylcholine biosynthetic process GO:2001245 2 0.014
carboxylic acid transport GO:0046942 100 0.014
intracellular mrna localization GO:0008298 4 0.014
protein polymerization GO:0051258 57 0.014
regulation of leukocyte differentiation GO:1902105 159 0.014
myotube differentiation GO:0014902 105 0.014
protein alkylation GO:0008213 81 0.014
Human Fly
production of molecular mediator of immune response GO:0002440 103 0.014
regulation of body fluid levels GO:0050878 162 0.014
nuclear division GO:0000280 158 0.014
germline cell cycle switching mitotic to meiotic cell cycle GO:0051729 1 0.014
axon ensheathment GO:0008366 76 0.014
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.014
cellular chemical homeostasis GO:0055082 215 0.014
cellular calcium ion homeostasis GO:0006874 119 0.014
learning or memory GO:0007611 148 0.014
cellular response to lipid GO:0071396 145 0.014
negative regulation of cytokine production GO:0001818 84 0.014
rho protein signal transduction GO:0007266 32 0.014
pallium development GO:0021543 120 0.014
regulation of protein stability GO:0031647 52 0.014
cellular metal ion homeostasis GO:0006875 151 0.014
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.013
negative regulation of organelle organization GO:0010639 90 0.013
purine containing compound catabolic process GO:0072523 213 0.013
defense response to other organism GO:0098542 197 0.013
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.013
regulation of ossification GO:0030278 112 0.013
activation of cysteine type endopeptidase activity GO:0097202 27 0.013
angiogenesis GO:0001525 201 0.013
cellular modified amino acid metabolic process GO:0006575 63 0.013
camera type eye development GO:0043010 266 0.013
protein methylation GO:0006479 81 0.013
Human Fly
regulation of multi organism process GO:0043900 111 0.013
regulation of map kinase activity GO:0043405 120 0.013
protein localization to membrane GO:0072657 108 0.013
regulation of exit from mitosis GO:0007096 1 0.013
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.013
regulation of protein complex assembly GO:0043254 83 0.013
organic acid biosynthetic process GO:0016053 86 0.013
pharynx development GO:0060465 1 0.013
cellular response to peptide hormone stimulus GO:0071375 92 0.013
regulation of cell activation GO:0050865 289 0.013
positive regulation of cysteine type endopeptidase activity GO:2001056 39 0.013
protein modification by small protein conjugation GO:0032446 187 0.013
body fluid secretion GO:0007589 53 0.013
negative regulation of dna replication GO:0008156 4 0.013
protein glycosylation GO:0006486 55 0.013
regulation of protein maturation GO:1903317 96 0.013
hormone secretion GO:0046879 128 0.013
positive regulation of nervous system development GO:0051962 221 0.013
metal ion homeostasis GO:0055065 189 0.013
localization within membrane GO:0051668 4 0.013
innate immune response GO:0045087 157 0.013
regulation of transmembrane transport GO:0034762 128 0.013
regulation of purine nucleotide catabolic process GO:0033121 122 0.013
renal system development GO:0072001 225 0.013
alcohol metabolic process GO:0006066 116 0.013
cellular response to oxidative stress GO:0034599 76 0.013
myelination GO:0042552 74 0.013
actin filament polymerization GO:0030041 44 0.013
axonogenesis GO:0007409 274 0.013
cellular response to arsenic containing substance GO:0071243 4 0.013
muscle contraction GO:0006936 101 0.013
lung development GO:0030324 164 0.013
digestive tract development GO:0048565 190 0.013
metencephalon development GO:0022037 89 0.013
cation transmembrane transport GO:0098655 266 0.013
carboxylic acid biosynthetic process GO:0046394 86 0.013
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.013
protein autophosphorylation GO:0046777 61 0.012
lymphocyte proliferation GO:0046651 164 0.012
peptide metabolic process GO:0006518 46 0.012
dna integrity checkpoint GO:0031570 28 0.012
Fly
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.012
second messenger mediated signaling GO:0019932 73 0.012
erythrocyte differentiation GO:0030218 88 0.012
response to osmotic stress GO:0006970 21 0.012
glial cell differentiation GO:0010001 131 0.012
peptide hormone secretion GO:0030072 109 0.012
guanosine containing compound metabolic process GO:1901068 144 0.012
regulation of lymphocyte activation GO:0051249 240 0.012
muscle fiber development GO:0048747 76 0.012
cellular response to peptide GO:1901653 92 0.012
embryonic placenta development GO:0001892 98 0.012
endocytosis GO:0006897 168 0.012
regulation of gtp catabolic process GO:0033124 113 0.012
kidney development GO:0001822 213 0.012
cellular response to cytokine stimulus GO:0071345 189 0.012
coenzyme metabolic process GO:0006732 52 0.012
response to extracellular stimulus GO:0009991 127 0.012
wound healing GO:0042060 157 0.012
negative regulation of neuron apoptotic process GO:0043524 92 0.012
blood vessel morphogenesis GO:0048514 285 0.012
regulation of response to wounding GO:1903034 189 0.012
actin polymerization or depolymerization GO:0008154 54 0.012
oligopeptide transmembrane transport GO:0035672 4 0.012
signal transduction involved in dna damage checkpoint GO:0072422 3 0.012
mrna metabolic process GO:0016071 84 0.012
regulation of ras protein signal transduction GO:0046578 114 0.012
negative regulation of immune system process GO:0002683 209 0.012
regulation of neuron differentiation GO:0045664 281 0.012
positive regulation of cell cycle process GO:0090068 61 0.012
cartilage development GO:0051216 140 0.012
microtubule cytoskeleton organization GO:0000226 157 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.012

Setd8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.028
cancer DOID:162 0 0.024
organ system cancer DOID:0050686 0 0.024
disease of anatomical entity DOID:7 0 0.020
nervous system disease DOID:863 0 0.020
myopathy DOID:423 0 0.018
muscular disease DOID:0080000 0 0.018
musculoskeletal system disease DOID:17 0 0.018
muscle tissue disease DOID:66 0 0.018
central nervous system disease DOID:331 0 0.016