Mus musculus

0 known processes

Amfr

autocrine motility factor receptor

(Aliases: gp78)

Amfr biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein catabolic process GO:0030163 221 0.695
Human
glycoprotein catabolic process GO:0006516 5 0.612
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.557
Human
glycoprotein metabolic process GO:0009100 116 0.496
cellular protein catabolic process GO:0044257 155 0.407
Human
modification dependent macromolecule catabolic process GO:0043632 133 0.248
Human
carbohydrate derivative catabolic process GO:1901136 231 0.202
response to endoplasmic reticulum stress GO:0034976 53 0.180
Human
ubiquitin dependent protein catabolic process GO:0006511 129 0.109
Human
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.092
Human
cellular macromolecule catabolic process GO:0044265 206 0.092
Human
spermatogenesis GO:0007283 284 0.077
regulation of cellular catabolic process GO:0031329 242 0.071
macromolecule catabolic process GO:0009057 281 0.070
Human
macromolecule glycosylation GO:0043413 55 0.066
male gamete generation GO:0048232 285 0.063
cellular response to topologically incorrect protein GO:0035967 25 0.061
Human
cellular amino acid metabolic process GO:0006520 103 0.059
organonitrogen compound catabolic process GO:1901565 264 0.058
endomembrane system organization GO:0010256 147 0.054
negative regulation of protein metabolic process GO:0051248 282 0.053
intracellular protein transport GO:0006886 204 0.051
retrograde protein transport er to cytosol GO:0030970 1 0.050
organophosphate catabolic process GO:0046434 232 0.050
protein ubiquitination GO:0016567 171 0.049
Human
regulation of protein catabolic process GO:0042176 108 0.047
glycosyl compound catabolic process GO:1901658 206 0.047
cellular nitrogen compound catabolic process GO:0044270 280 0.046
glycoprotein biosynthetic process GO:0009101 89 0.046
regulation of protein localization GO:0032880 231 0.046
nucleoside catabolic process GO:0009164 206 0.044
nucleoside phosphate catabolic process GO:1901292 222 0.044
response to topologically incorrect protein GO:0035966 25 0.044
Human
protein localization to organelle GO:0033365 185 0.042
nucleoside triphosphate metabolic process GO:0009141 230 0.042
positive regulation of programmed cell death GO:0043068 218 0.040
negative regulation of cellular protein metabolic process GO:0032269 247 0.040
cell growth GO:0016049 130 0.039
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 3 0.039
ribonucleoside metabolic process GO:0009119 245 0.039
nucleoside metabolic process GO:0009116 246 0.039
protein modification by small protein conjugation or removal GO:0070647 207 0.039
Human
apoptotic signaling pathway GO:0097190 306 0.037
purine nucleoside catabolic process GO:0006152 205 0.037
anion transport GO:0006820 177 0.034
organic cyclic compound catabolic process GO:1901361 295 0.034
transmembrane transport GO:0055085 412 0.033
protein localization to membrane GO:0072657 108 0.033
regulation of apoptotic signaling pathway GO:2001233 197 0.032
carbohydrate derivative biosynthetic process GO:1901137 183 0.032
purine ribonucleotide catabolic process GO:0009154 208 0.032
cell cell recognition GO:0009988 44 0.032
purine nucleotide catabolic process GO:0006195 211 0.031
purine nucleoside metabolic process GO:0042278 241 0.031
ribonucleoside triphosphate catabolic process GO:0009203 199 0.030
protein modification by small protein conjugation GO:0032446 187 0.030
Human
nucleoside triphosphate catabolic process GO:0009143 205 0.030
modification dependent protein catabolic process GO:0019941 133 0.029
Human
ribonucleoside triphosphate metabolic process GO:0009199 220 0.029
protein oligomerization GO:0051259 67 0.029
Human
organelle fission GO:0048285 170 0.029
regulation of cellular ketone metabolic process GO:0010565 66 0.028
ribose phosphate metabolic process GO:0019693 291 0.028
positive regulation of apoptotic process GO:0043065 217 0.028
regulation of transferase activity GO:0051338 263 0.028
negative regulation of molecular function GO:0044092 258 0.028
amine metabolic process GO:0009308 45 0.028
leukocyte differentiation GO:0002521 342 0.027
cellular ketone metabolic process GO:0042180 84 0.027
organelle membrane fusion GO:0090174 1 0.027
purine nucleotide metabolic process GO:0006163 302 0.027
cellular amine metabolic process GO:0044106 44 0.027
glycosyl compound metabolic process GO:1901657 246 0.027
axonogenesis GO:0007409 274 0.027
ribonucleotide metabolic process GO:0009259 291 0.026
regulation of cellular protein catabolic process GO:1903362 61 0.026
meiotic nuclear division GO:0007126 115 0.025
protein glycosylation GO:0006486 55 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.025
ribonucleoside catabolic process GO:0042454 206 0.025
mitotic cell cycle GO:0000278 195 0.025
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.025
peptidyl amino acid modification GO:0018193 336 0.025
organic hydroxy compound metabolic process GO:1901615 203 0.024
regulation of cellular amino acid metabolic process GO:0006521 5 0.024
extrinsic apoptotic signaling pathway GO:0097191 126 0.024
endoplasmic reticulum unfolded protein response GO:0030968 19 0.024
Human
purine nucleoside triphosphate metabolic process GO:0009144 226 0.024
protein maturation GO:0051604 176 0.024
nucleotide catabolic process GO:0009166 217 0.024
regulation of organelle organization GO:0033043 289 0.023
positive regulation of protein modification process GO:0031401 299 0.023
regulation of neuron differentiation GO:0045664 281 0.023
chemotaxis GO:0006935 247 0.023
inclusion body assembly GO:0070841 3 0.023
carbohydrate metabolic process GO:0005975 230 0.023
positive regulation of transferase activity GO:0051347 167 0.023
meiotic cell cycle GO:0051321 122 0.023
nucleoside phosphate metabolic process GO:0006753 338 0.022
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.022
aromatic compound catabolic process GO:0019439 286 0.022
translesion synthesis GO:0019985 1 0.022
proteasomal protein catabolic process GO:0010498 98 0.021
Human
regulation of hydrolase activity GO:0051336 246 0.021
regulation of cellular response to stress GO:0080135 159 0.021
purine containing compound metabolic process GO:0072521 311 0.021
neuronal action potential GO:0019228 54 0.021
regulation of cell activation GO:0050865 289 0.021
positive regulation of cellular catabolic process GO:0031331 148 0.021
cellular response to misfolded protein GO:0071218 5 0.021
plasma membrane organization GO:0007009 90 0.021
phospholipid metabolic process GO:0006644 87 0.021
cellular response to amino acid stimulus GO:0071230 29 0.020
heterocycle catabolic process GO:0046700 280 0.020
autophagy GO:0006914 45 0.020
nucleobase containing small molecule metabolic process GO:0055086 352 0.020
action potential GO:0001508 78 0.020
purine ribonucleoside metabolic process GO:0046128 241 0.020
purine ribonucleotide metabolic process GO:0009150 290 0.020
cellular lipid metabolic process GO:0044255 323 0.020
organonitrogen compound biosynthetic process GO:1901566 192 0.019
regulation of cellular amine metabolic process GO:0033238 20 0.019
lipid biosynthetic process GO:0008610 179 0.019
positive regulation of growth GO:0045927 104 0.019
purine ribonucleoside catabolic process GO:0046130 205 0.019
regulation of mrna polyadenylation GO:1900363 1 0.019
t cell activation GO:0042110 289 0.018
ribonucleotide catabolic process GO:0009261 208 0.018
cellular homeostasis GO:0019725 240 0.018
transmission of nerve impulse GO:0019226 76 0.018
cellular response to dna damage stimulus GO:0006974 207 0.018
regulation of cytoplasmic translation GO:2000765 4 0.018
mapk cascade GO:0000165 281 0.018
negative regulation of cell proliferation GO:0008285 296 0.018
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.018
purine containing compound catabolic process GO:0072523 213 0.017
regulation of proteolysis GO:0030162 164 0.017
fertilization GO:0009566 127 0.017
microtubule based process GO:0007017 236 0.017
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.017
organelle disassembly GO:1903008 2 0.017
positive regulation of neuron projection development GO:0010976 79 0.017
cytoplasmic transport GO:0016482 234 0.017
intrinsic apoptotic signaling pathway GO:0097193 132 0.017
regulation of membrane potential GO:0042391 192 0.017
dna metabolic process GO:0006259 303 0.017
regulation of protein transport GO:0051223 163 0.017
response to nutrient levels GO:0031667 109 0.017
neuron projection guidance GO:0097485 141 0.017
atp metabolic process GO:0046034 75 0.017
regulation of inflammatory response GO:0050727 147 0.016
anatomical structure homeostasis GO:0060249 145 0.016
negative regulation of cellular component organization GO:0051129 194 0.016
cellular response to starvation GO:0009267 57 0.016
mitochondrion organization GO:0007005 134 0.016
nucleotide metabolic process GO:0009117 332 0.016
positive regulation of hydrolase activity GO:0051345 148 0.016
regulation of lipid metabolic process GO:0019216 118 0.016
myeloid leukocyte differentiation GO:0002573 119 0.016
sterol metabolic process GO:0016125 58 0.016
response to oxidative stress GO:0006979 123 0.016
cellular response to oxidative stress GO:0034599 76 0.016
regulation of protein maturation GO:1903317 96 0.016
regulation of secretion GO:0051046 274 0.016
establishment of protein localization to organelle GO:0072594 118 0.016
multicellular organism growth GO:0035264 161 0.016
microtubule cytoskeleton organization GO:0000226 157 0.016
cellular response to cadmium ion GO:0071276 3 0.016
negative regulation of multi organism process GO:0043901 68 0.016
oxidation reduction process GO:0055114 342 0.015
divalent inorganic cation transport GO:0072511 178 0.015
cell adhesion GO:0007155 329 0.015
regulation of protein processing GO:0070613 96 0.015
response to acid chemical GO:0001101 111 0.015
posttranscriptional regulation of gene expression GO:0010608 155 0.015
response to inorganic substance GO:0010035 96 0.015
glycosylation GO:0070085 62 0.015
organic anion transport GO:0015711 137 0.015
multicellular organismal signaling GO:0035637 91 0.015
oocyte anterior posterior axis specification GO:0007314 2 0.015
regulation of kinase activity GO:0043549 249 0.015
er nucleus signaling pathway GO:0006984 27 0.015
Human
response to radiation GO:0009314 165 0.015
maintenance of location GO:0051235 89 0.015
cation homeostasis GO:0055080 212 0.015
regulation of lymphocyte activation GO:0051249 240 0.015
positive regulation of lymphocyte activation GO:0051251 140 0.015
calcium ion transport GO:0006816 159 0.015
sperm egg recognition GO:0035036 37 0.015
guanosine containing compound metabolic process GO:1901068 144 0.015
nucleoside monophosphate metabolic process GO:0009123 85 0.015
protein localization to nucleus GO:0034504 121 0.015
binding of sperm to zona pellucida GO:0007339 34 0.015
regulation of peptidase activity GO:0052547 96 0.015
metal ion homeostasis GO:0055065 189 0.014
regulation of map kinase activity GO:0043405 120 0.014
regulation of chromosome organization GO:0033044 83 0.014
localization within membrane GO:0051668 4 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.014
pole plasm assembly GO:0007315 2 0.014
ribonucleoside monophosphate metabolic process GO:0009161 80 0.014
negative regulation of protein phosphorylation GO:0001933 126 0.014
maternal determination of anterior posterior axis embryo GO:0008358 2 0.014
small gtpase mediated signal transduction GO:0007264 97 0.014
germ cell development GO:0007281 185 0.014
response to light stimulus GO:0009416 135 0.014
lateral inhibition GO:0046331 1 0.014
ribonucleoside monophosphate catabolic process GO:0009158 57 0.014
regulation of defense response GO:0031347 233 0.014
ossification GO:0001503 216 0.014
epidermis development GO:0008544 187 0.013
inflammatory response GO:0006954 244 0.013
negative regulation of cellular catabolic process GO:0031330 47 0.013
regulation of lymphocyte differentiation GO:0045619 107 0.013
reactive oxygen species metabolic process GO:0072593 84 0.013
regulation of establishment of protein localization GO:0070201 181 0.013
epithelial cell development GO:0002064 159 0.013
regulation of protein serine threonine kinase activity GO:0071900 157 0.013
cellular chemical homeostasis GO:0055082 215 0.013
divalent metal ion transport GO:0070838 172 0.013
lymphocyte differentiation GO:0030098 242 0.013
cellularization GO:0007349 1 0.013
response to extracellular stimulus GO:0009991 127 0.013
regulation of purine nucleotide catabolic process GO:0033121 122 0.013
cellular response to extracellular stimulus GO:0031668 81 0.013
organelle assembly GO:0070925 177 0.013
positive regulation of cell death GO:0010942 224 0.013
positive regulation of nervous system development GO:0051962 221 0.013
negative regulation of synapse assembly GO:0051964 3 0.013
regulation of intracellular transport GO:0032386 159 0.013
cell type specific apoptotic process GO:0097285 268 0.013
cellular response to acid chemical GO:0071229 68 0.013
central nervous system neuron differentiation GO:0021953 162 0.013
atp catabolic process GO:0006200 55 0.013
nuclear division GO:0000280 158 0.013
positive regulation of cell development GO:0010720 237 0.013
monocarboxylic acid metabolic process GO:0032787 191 0.012
dna repair GO:0006281 107 0.012
regulation of reactive oxygen species metabolic process GO:2000377 40 0.012
regulation of cellular component biogenesis GO:0044087 181 0.012
locomotory behavior GO:0007626 195 0.012
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 25 0.012
myelination GO:0042552 74 0.012
regulation of protein kinase activity GO:0045859 232 0.012
regulation of protein ubiquitination GO:0031396 52 0.012
ras protein signal transduction GO:0007265 77 0.012
response to growth factor GO:0070848 198 0.012
establishment of protein localization to membrane GO:0090150 54 0.012
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.012
cell recognition GO:0008037 83 0.012
protein secretion GO:0009306 111 0.012
regulation of leukocyte differentiation GO:1902105 159 0.012
regulation of plasma lipoprotein particle levels GO:0097006 23 0.012
skeletal muscle organ development GO:0060538 163 0.012
regulation of secretion by cell GO:1903530 249 0.012
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.012
sulfur compound metabolic process GO:0006790 100 0.012
positive regulation of cellular amine metabolic process GO:0033240 5 0.012
negative regulation of nervous system development GO:0051961 156 0.012
positive regulation of neuron differentiation GO:0045666 141 0.012
purine nucleoside monophosphate metabolic process GO:0009126 81 0.012
regulation of ion transport GO:0043269 215 0.012
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.012
small molecule biosynthetic process GO:0044283 132 0.012
cellular response to cytokine stimulus GO:0071345 189 0.012
zymogen activation GO:0031638 41 0.012
cholesterol metabolic process GO:0008203 56 0.012
regulation of cytokine production GO:0001817 266 0.012
negative regulation of protein modification process GO:0031400 163 0.011
negative regulation of defense response GO:0031348 77 0.011
regulation of purine nucleotide metabolic process GO:1900542 169 0.011
establishment of organelle localization GO:0051656 122 0.011
calcium ion homeostasis GO:0055074 127 0.011
synapse organization GO:0050808 125 0.011
macromolecular complex disassembly GO:0032984 43 0.011
translation GO:0006412 93 0.011
cellular response to growth factor stimulus GO:0071363 197 0.011
regulation of protein secretion GO:0050708 82 0.011
single fertilization GO:0007338 82 0.011
cellular ion homeostasis GO:0006873 165 0.011
nuclear transport GO:0051169 139 0.011
regulation of multi organism process GO:0043900 111 0.011
regulation of cell migration GO:0030334 219 0.011
microtubule cytoskeleton organization involved in mitosis GO:1902850 4 0.011
nitrogen compound transport GO:0071705 271 0.011
homeostasis of number of cells GO:0048872 210 0.011
midgut development GO:0007494 4 0.011
regulation of circadian sleep wake cycle GO:0042749 3 0.011
rna processing GO:0006396 105 0.011
myeloid cell differentiation GO:0030099 233 0.011
positive regulation of glial cell proliferation GO:0060252 4 0.011
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 22 0.011
skin development GO:0043588 220 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.011
neuron death GO:0070997 154 0.010
endocytosis GO:0006897 168 0.010
muscle tissue development GO:0060537 308 0.010
mitotic cell cycle process GO:1903047 159 0.010
regulation of reproductive process GO:2000241 66 0.010
myotube differentiation GO:0014902 105 0.010
protein targeting GO:0006605 143 0.010
negative regulation of apoptotic signaling pathway GO:2001234 104 0.010
regulation of cell growth GO:0001558 91 0.010
forebrain development GO:0030900 302 0.010
intracellular mrna localization GO:0008298 4 0.010
cell maturation GO:0048469 127 0.010
positive regulation of protein modification by small protein conjugation or removal GO:1903322 30 0.010
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.010
multicellular organismal homeostasis GO:0048871 164 0.010
cellular modified amino acid metabolic process GO:0006575 63 0.010
gtp metabolic process GO:0046039 144 0.010
regulation of cysteine type endopeptidase activity GO:2000116 65 0.010
positive regulation of membrane protein ectodomain proteolysis GO:0051044 3 0.010
tissue remodeling GO:0048771 102 0.010
cellular response to external stimulus GO:0071496 88 0.010
axon ensheathment GO:0008366 76 0.010
cellular response to lipid GO:0071396 145 0.010
glial cell differentiation GO:0010001 131 0.010
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.010
regulation of response to wounding GO:1903034 189 0.010
carboxylic acid transport GO:0046942 100 0.010

Amfr disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.088
nervous system disease DOID:863 0 0.088
central nervous system disease DOID:331 0 0.027
disease of metabolism DOID:0014667 0 0.026
musculoskeletal system disease DOID:17 0 0.022
sensory system disease DOID:0050155 0 0.021
eye and adnexa disease DOID:1492 0 0.020
eye disease DOID:5614 0 0.020
motor neuron disease DOID:231 0 0.019
neurodegenerative disease DOID:1289 0 0.019
inherited metabolic disorder DOID:655 0 0.017
connective tissue disease DOID:65 0 0.016
bone development disease DOID:0080006 0 0.016
bone disease DOID:0080001 0 0.016
retinal disease DOID:5679 0 0.013
retinal degeneration DOID:8466 0 0.013
disease of cellular proliferation DOID:14566 0 0.011
brain disease DOID:936 0 0.011
cancer DOID:162 0 0.010