|
oxidation reduction process
|
GO:0055114 |
342 |
0.363
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.176
|
|
|
cellular modified amino acid metabolic process
|
GO:0006575 |
63 |
0.137
|
|
|
glutathione metabolic process
|
GO:0006749 |
16 |
0.127
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
191 |
0.116
|
Mouse |
|
sulfur compound metabolic process
|
GO:0006790 |
100 |
0.078
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.074
|
|
|
aldehyde catabolic process
|
GO:0046185 |
4 |
0.063
|
|
|
cation transport
|
GO:0006812 |
399 |
0.062
|
|
|
response to oxidative stress
|
GO:0006979 |
123 |
0.058
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.056
|
Rat |
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.055
|
Human |
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.054
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.054
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.052
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.050
|
Mouse |
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.048
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.046
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.044
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.043
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.039
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.039
|
|
|
response to nitrosative stress
|
GO:0051409 |
1 |
0.038
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.038
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.038
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.037
|
|
|
xenobiotic catabolic process
|
GO:0042178 |
1 |
0.037
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.036
|
Worm |
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.035
|
|
|
lipid biosynthetic process
|
GO:0008610 |
179 |
0.034
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
132 |
0.034
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
133 |
0.034
|
|
|
alcohol metabolic process
|
GO:0006066 |
116 |
0.033
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.033
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.032
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.032
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.031
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.030
|
|
|
ketone catabolic process
|
GO:0042182 |
3 |
0.030
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.029
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.029
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.028
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.028
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.028
|
Mouse |
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.028
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.028
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.027
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.027
|
|
|
blood circulation
|
GO:0008015 |
195 |
0.027
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.027
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.026
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
129 |
0.026
|
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.025
|
Rat Worm |
|
cellular amide metabolic process
|
GO:0043603 |
58 |
0.025
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.025
|
|
|
carboxylic acid biosynthetic process
|
GO:0046394 |
86 |
0.025
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.025
|
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.024
|
Rat |
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.024
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.024
|
|
|
gland development
|
GO:0048732 |
330 |
0.024
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.024
|
|
|
steroid metabolic process
|
GO:0008202 |
119 |
0.023
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.023
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
133 |
0.023
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
234 |
0.023
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.023
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.023
|
Human |
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.023
|
Mouse |
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.023
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.023
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.022
|
Mouse Rat |
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.022
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.022
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.022
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.021
|
|
|
l ascorbic acid metabolic process
|
GO:0019852 |
4 |
0.021
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.021
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.021
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.021
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.021
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.020
|
|
|
lipid localization
|
GO:0010876 |
126 |
0.020
|
Worm |
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.020
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.020
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.020
|
|
|
cation transmembrane transport
|
GO:0098655 |
266 |
0.019
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.019
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.019
|
Rat |
|
cation homeostasis
|
GO:0055080 |
212 |
0.019
|
|
|
muscle contraction
|
GO:0006936 |
101 |
0.019
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.019
|
|
|
cellular protein catabolic process
|
GO:0044257 |
155 |
0.019
|
|
|
peptide metabolic process
|
GO:0006518 |
46 |
0.018
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.018
|
Worm |
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.018
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.018
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.018
|
|
|
fatty acid metabolic process
|
GO:0006631 |
121 |
0.018
|
Mouse |
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.018
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.018
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.017
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.017
|
|
|
monosaccharide metabolic process
|
GO:0005996 |
106 |
0.017
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.017
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.017
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.017
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.017
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.017
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.017
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
207 |
0.017
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.016
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.016
|
Worm |
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.016
|
|
|
organic acid biosynthetic process
|
GO:0016053 |
86 |
0.016
|
|
|
gonad development
|
GO:0008406 |
141 |
0.016
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.016
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.016
|
|
|
lateral inhibition
|
GO:0046331 |
1 |
0.016
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.016
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.016
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.016
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.016
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.016
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.016
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
108 |
0.016
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.016
|
|
|
cofactor metabolic process
|
GO:0051186 |
80 |
0.015
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
11 |
0.015
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.015
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.015
|
|
|
peptide transport
|
GO:0015833 |
133 |
0.015
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.015
|
|
|
nitrobenzene metabolic process
|
GO:0018916 |
1 |
0.015
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
88 |
0.015
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.015
|
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.015
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.015
|
|
|
cellular aldehyde metabolic process
|
GO:0006081 |
12 |
0.015
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.015
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.015
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.015
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.015
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.015
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.015
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.015
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.014
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.014
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.014
|
|
|
hormone metabolic process
|
GO:0042445 |
86 |
0.014
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.014
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.014
|
|
|
heart contraction
|
GO:0060047 |
93 |
0.014
|
|
|
alpha amino acid metabolic process
|
GO:1901605 |
59 |
0.014
|
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.014
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.014
|
|
|
heart process
|
GO:0003015 |
94 |
0.014
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.014
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.014
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.014
|
Rat |
|
dna metabolic process
|
GO:0006259 |
303 |
0.014
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.014
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.014
|
Human |
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
147 |
0.014
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.013
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.013
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.013
|
|
|
locomotory behavior
|
GO:0007626 |
195 |
0.013
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
2 |
0.013
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.013
|
Human |
|
response to amino acid
|
GO:0043200 |
37 |
0.013
|
Rat |
|
proteasomal protein catabolic process
|
GO:0010498 |
98 |
0.013
|
|
|
rhythmic process
|
GO:0048511 |
174 |
0.013
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.013
|
|
|
methylation
|
GO:0032259 |
134 |
0.013
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.013
|
|
|
regulation of peptidase activity
|
GO:0052547 |
96 |
0.013
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.013
|
|
|
response to reactive oxygen species
|
GO:0000302 |
56 |
0.013
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.013
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.013
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.013
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.013
|
|
|
response to extracellular stimulus
|
GO:0009991 |
127 |
0.013
|
Rat |
|
endocytosis
|
GO:0006897 |
168 |
0.013
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
85 |
0.013
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.012
|
|
|
adult locomotory behavior
|
GO:0008344 |
91 |
0.012
|
|
|
response to metal ion
|
GO:0010038 |
47 |
0.012
|
Rat |
|
response to nutrient levels
|
GO:0031667 |
109 |
0.012
|
Rat |
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.012
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
118 |
0.012
|
|
|
cellular protein complex assembly
|
GO:0043623 |
116 |
0.012
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.012
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
76 |
0.012
|
|
|
response to alcohol
|
GO:0097305 |
48 |
0.012
|
Rat |
|
action potential
|
GO:0001508 |
78 |
0.012
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.012
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.012
|
|
|
skin development
|
GO:0043588 |
220 |
0.012
|
|
|
amide transport
|
GO:0042886 |
138 |
0.012
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.012
|
|
|
response to light stimulus
|
GO:0009416 |
135 |
0.012
|
Worm |
|
protein ubiquitination
|
GO:0016567 |
171 |
0.012
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.012
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.012
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.012
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.012
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.012
|
|
|
multi multicellular organism process
|
GO:0044706 |
109 |
0.012
|
|
|
renal system development
|
GO:0072001 |
225 |
0.012
|
Mouse |
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
139 |
0.011
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.011
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.011
|
|
|
muscle system process
|
GO:0003012 |
141 |
0.011
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.011
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.011
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.011
|
|
|
male sex differentiation
|
GO:0046661 |
109 |
0.011
|
|
|
regulation of transporter activity
|
GO:0032409 |
57 |
0.011
|
|
|
circadian rhythm
|
GO:0007623 |
114 |
0.011
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.011
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.011
|
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.011
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.011
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.011
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.011
|
|
|
response to drug
|
GO:0042493 |
75 |
0.011
|
|
|
cellular amino acid biosynthetic process
|
GO:0008652 |
22 |
0.011
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.011
|
|
|
coenzyme metabolic process
|
GO:0006732 |
52 |
0.011
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
128 |
0.011
|
|
|
respiratory system development
|
GO:0060541 |
190 |
0.011
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.011
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.011
|
|
|
alpha amino acid biosynthetic process
|
GO:1901607 |
15 |
0.011
|
|
|
cellular response to inorganic substance
|
GO:0071241 |
37 |
0.010
|
|
|
acetylcholine transport
|
GO:0015870 |
2 |
0.010
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.010
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.010
|
|
|
chromatin organization
|
GO:0006325 |
206 |
0.010
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.010
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.010
|
|
|
regulation of peptide transport
|
GO:0090087 |
91 |
0.010
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.010
|
|
|
interleukin 8 production
|
GO:0032637 |
4 |
0.010
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.010
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.010
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.010
|
|
|
tissue homeostasis
|
GO:0001894 |
115 |
0.010
|
|
|
response to oxygen levels
|
GO:0070482 |
62 |
0.010
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.010
|
|
|
neuronal action potential
|
GO:0019228 |
54 |
0.010
|
|
|
peptide hormone secretion
|
GO:0030072 |
109 |
0.010
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.010
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.010
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.010
|
Mouse |