|
|
immune effector process
|
GO:0002252 |
321 |
0.960
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.939
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.933
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.931
|
Human |
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.904
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.889
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.885
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.869
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.864
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.849
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.847
|
Human |
|
|
t cell activation
|
GO:0042110 |
289 |
0.846
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.824
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.819
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.814
|
|
|
|
defense response to virus
|
GO:0051607 |
68 |
0.798
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.777
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.734
|
|
|
|
t cell receptor signaling pathway
|
GO:0050852 |
46 |
0.728
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.691
|
|
|
|
positive regulation of cytokine secretion
|
GO:0050715 |
41 |
0.690
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.677
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.675
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.670
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.665
|
Human |
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.655
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
64 |
0.651
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.645
|
|
|
|
calcium ion transport into cytosol
|
GO:0060402 |
48 |
0.638
|
|
|
|
t cell selection
|
GO:0045058 |
34 |
0.635
|
Human |
|
|
regulation of calcium mediated signaling
|
GO:0050848 |
19 |
0.634
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.630
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.625
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.619
|
|
|
|
positive regulation of adaptive immune response
|
GO:0002821 |
61 |
0.614
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.612
|
|
|
|
alpha beta t cell proliferation
|
GO:0046633 |
21 |
0.611
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.604
|
|
|
|
leukocyte degranulation
|
GO:0043299 |
27 |
0.598
|
|
|
|
b cell proliferation
|
GO:0042100 |
53 |
0.598
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.595
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.587
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.567
|
|
|
|
regulation of alpha beta t cell proliferation
|
GO:0046640 |
18 |
0.565
|
|
|
|
hematopoietic stem cell migration
|
GO:0035701 |
1 |
0.562
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.557
|
|
|
|
myeloid cell activation involved in immune response
|
GO:0002275 |
34 |
0.545
|
|
|
|
dendritic cell differentiation
|
GO:0097028 |
26 |
0.518
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.515
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.515
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
18 |
0.515
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.514
|
|
|
|
mast cell activation involved in immune response
|
GO:0002279 |
20 |
0.498
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.493
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.490
|
|
|
|
regulation of antigen receptor mediated signaling pathway
|
GO:0050854 |
29 |
0.483
|
|
|
|
positive regulation of cytokine biosynthetic process
|
GO:0042108 |
40 |
0.479
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.479
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.471
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.463
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.457
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.456
|
|
|
|
positive regulation of protein secretion
|
GO:0050714 |
52 |
0.450
|
|
|
|
calcium mediated signaling
|
GO:0019722 |
46 |
0.442
|
|
|
|
cytokine secretion
|
GO:0050663 |
72 |
0.440
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.428
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.424
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.412
|
|
|
|
negative thymic t cell selection
|
GO:0045060 |
12 |
0.404
|
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.395
|
|
|
|
thymic t cell selection
|
GO:0045061 |
22 |
0.394
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.394
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.393
|
|
|
|
mast cell activation
|
GO:0045576 |
27 |
0.392
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.378
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.376
|
|
|
|
positive regulation of calcium mediated signaling
|
GO:0050850 |
15 |
0.373
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.364
|
|
|
|
regulation of b cell activation
|
GO:0050864 |
81 |
0.356
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.351
|
Human |
|
|
somatic diversification of immune receptors via germline recombination within a single locus
|
GO:0002562 |
51 |
0.342
|
|
|
|
regulated secretory pathway
|
GO:0045055 |
32 |
0.341
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.335
|
|
|
|
myeloid leukocyte mediated immunity
|
GO:0002444 |
42 |
0.335
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.334
|
|
|
|
ensheathment of neurons
|
GO:0007272 |
76 |
0.333
|
|
|
|
regulation of mast cell activation involved in immune response
|
GO:0033006 |
17 |
0.332
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.327
|
|
|
|
positive regulation of t cell proliferation
|
GO:0042102 |
52 |
0.322
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.318
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.316
|
|
|
|
inflammatory response to antigenic stimulus
|
GO:0002437 |
30 |
0.309
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.308
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.307
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.306
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.303
|
|
|
|
jnk cascade
|
GO:0007254 |
72 |
0.302
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.297
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.297
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.297
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.296
|
|
|
|
regulation of toll like receptor 4 signaling pathway
|
GO:0034143 |
4 |
0.292
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.290
|
|
|
|
positive regulation of gamma delta t cell differentiation
|
GO:0045588 |
6 |
0.287
|
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
59 |
0.284
|
|
|
|
neuron migration
|
GO:0001764 |
122 |
0.282
|
|
|
|
negative regulation of t cell activation
|
GO:0050868 |
65 |
0.282
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.282
|
|
|
|
negative regulation of lymphocyte proliferation
|
GO:0050672 |
45 |
0.279
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.279
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.274
|
|
|
|
regulation of cytokine secretion
|
GO:0050707 |
61 |
0.271
|
|
|
|
regulation of interferon gamma production
|
GO:0032649 |
57 |
0.267
|
|
|
|
regulation of mast cell activation
|
GO:0033003 |
21 |
0.263
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.262
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.261
|
|
|
|
humoral immune response
|
GO:0006959 |
57 |
0.261
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
82 |
0.260
|
|
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
84 |
0.259
|
|
|
|
regulation of interleukin 2 production
|
GO:0032663 |
28 |
0.258
|
|
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
69 |
0.257
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.255
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.255
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.251
|
|
|
|
mature dendritic cell differentiation
|
GO:0097029 |
3 |
0.249
|
|
|
|
positive regulation of t cell costimulation
|
GO:2000525 |
2 |
0.243
|
|
|
|
positive regulation of alpha beta t cell activation
|
GO:0046635 |
39 |
0.242
|
|
|
|
t cell mediated immunity
|
GO:0002456 |
50 |
0.242
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.241
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
61 |
0.240
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.240
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.238
|
|
|
|
negative regulation of b cell proliferation
|
GO:0030889 |
13 |
0.237
|
|
|
|
organelle fission
|
GO:0048285 |
170 |
0.236
|
|
|
|
muscle system process
|
GO:0003012 |
141 |
0.232
|
|
|
|
negative regulation of b cell activation
|
GO:0050869 |
27 |
0.231
|
|
|
|
t cell costimulation
|
GO:0031295 |
14 |
0.230
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.230
|
|
|
|
positive regulation of b cell activation
|
GO:0050871 |
49 |
0.228
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
70 |
0.228
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.224
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.222
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.220
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
69 |
0.214
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.214
|
|
|
|
mast cell degranulation
|
GO:0043303 |
19 |
0.212
|
|
|
|
positive regulation of immunological synapse formation
|
GO:2000522 |
1 |
0.211
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.211
|
|
|
|
negative regulation of leukocyte proliferation
|
GO:0070664 |
46 |
0.207
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.204
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.202
|
Human |
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.201
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.201
|
|
|
|
positive regulation of monocyte extravasation
|
GO:2000439 |
1 |
0.200
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.197
|
|
|
|
eosinophil activation
|
GO:0043307 |
1 |
0.196
|
|
|
|
positive regulation of inflammatory response to antigenic stimulus
|
GO:0002863 |
11 |
0.194
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.194
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.193
|
|
|
|
cytokine metabolic process
|
GO:0042107 |
71 |
0.193
|
|
|
|
regulation of monocyte chemotaxis
|
GO:0090025 |
3 |
0.192
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.188
|
|
|
|
positive t cell selection
|
GO:0043368 |
23 |
0.187
|
|
|
|
neuronal action potential
|
GO:0019228 |
54 |
0.185
|
|
|
|
osteoclast differentiation
|
GO:0030316 |
62 |
0.185
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.184
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.183
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.179
|
|
|
|
regulation of myeloid leukocyte mediated immunity
|
GO:0002886 |
25 |
0.174
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.173
|
|
|
|
regulation of b cell proliferation
|
GO:0030888 |
39 |
0.173
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.169
|
|
|
|
regulation of alpha beta t cell differentiation
|
GO:0046637 |
35 |
0.169
|
|
|
|
cd8 positive alpha beta t cell extravasation
|
GO:0035697 |
3 |
0.167
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.161
|
|
|
|
positive regulation of alpha beta t cell proliferation
|
GO:0046641 |
12 |
0.161
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
71 |
0.160
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.159
|
|
|
|
mast cell mediated immunity
|
GO:0002448 |
20 |
0.157
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.154
|
|
|
|
release of sequestered calcium ion into cytosol
|
GO:0051209 |
42 |
0.153
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.148
|
|
|
|
negative regulation of synapse assembly
|
GO:0051964 |
3 |
0.147
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.147
|
|
|
|
regulation of t cell receptor signaling pathway
|
GO:0050856 |
21 |
0.146
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
48 |
0.146
|
|
|
|
positive regulation of hematopoietic stem cell migration
|
GO:2000473 |
1 |
0.144
|
|
|
|
positive regulation of b cell receptor signaling pathway
|
GO:0050861 |
4 |
0.142
|
|
|
|
protein secretion
|
GO:0009306 |
111 |
0.142
|
|
|
|
eosinophil degranulation
|
GO:0043308 |
1 |
0.140
|
|
|
|
negative regulation of immune effector process
|
GO:0002698 |
55 |
0.140
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.140
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
19 |
0.139
|
|
|
|
somatic recombination of immunoglobulin gene segments
|
GO:0016447 |
42 |
0.139
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
73 |
0.139
|
|
|
|
regulation of smooth muscle contraction
|
GO:0006940 |
22 |
0.136
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.136
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.136
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.133
|
|
|
|
b cell receptor signaling pathway
|
GO:0050853 |
20 |
0.132
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
87 |
0.130
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.130
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.130
|
|
|
|
regulation of eosinophil degranulation
|
GO:0043309 |
1 |
0.129
|
|
|
|
positive regulation of t cell receptor signaling pathway
|
GO:0050862 |
4 |
0.129
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.127
|
|
|
|
natural killer cell inhibitory signaling pathway
|
GO:0002769 |
2 |
0.127
|
|
|
|
somatic cell dna recombination
|
GO:0016444 |
51 |
0.126
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
74 |
0.125
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.125
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.123
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.121
|
Human |
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.121
|
|
|
|
somatic diversification of immunoglobulins
|
GO:0016445 |
43 |
0.119
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.119
|
|
|
|
cellular response to interleukin 15
|
GO:0071350 |
2 |
0.118
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
43 |
0.118
|
|
|
|
negative regulation of adaptive immune response
|
GO:0002820 |
25 |
0.118
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
93 |
0.117
|
|
|
|
positive regulation of regulated secretory pathway
|
GO:1903307 |
10 |
0.116
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.115
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.114
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
70 |
0.113
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.113
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.113
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.113
|
|
|
|
tissue homeostasis
|
GO:0001894 |
115 |
0.112
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.111
|
|
|
|
leukocyte homeostasis
|
GO:0001776 |
79 |
0.110
|
|
|
|
immune complex clearance
|
GO:0002434 |
2 |
0.109
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.109
|
|
|
|
detection of mechanical stimulus involved in sensory perception of pain
|
GO:0050966 |
4 |
0.107
|
|
|
|
activation of mapk activity
|
GO:0000187 |
59 |
0.106
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.106
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.106
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.106
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.106
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
88 |
0.105
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.105
|
|
|
|
positive regulation of inflammatory response
|
GO:0050729 |
47 |
0.105
|
|
|
|
mast cell proliferation
|
GO:0070662 |
4 |
0.104
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.104
|
|
|
|
isotype switching
|
GO:0045190 |
36 |
0.103
|
|
|
|
somatic diversification of immune receptors
|
GO:0002200 |
53 |
0.100
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.100
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.099
|
|
|
|
negative t cell selection
|
GO:0043383 |
13 |
0.098
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.097
|
|
|
|
regulation of muscle contraction
|
GO:0006937 |
49 |
0.097
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.096
|
|
|
|
regulation of inflammatory response to antigenic stimulus
|
GO:0002861 |
21 |
0.096
|
|
|
|
positive regulation of leukocyte mediated immunity
|
GO:0002705 |
70 |
0.096
|
|
|
|
cerebral cortex development
|
GO:0021987 |
86 |
0.096
|
|
|
|
regulation of dendritic cell apoptotic process
|
GO:2000668 |
3 |
0.096
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
58 |
0.095
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
116 |
0.095
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.095
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.095
|
|
|
|
helper t cell chemotaxis
|
GO:0035704 |
1 |
0.093
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
61 |
0.093
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.092
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.092
|
|
|
|
regulation of mast cell proliferation
|
GO:0070666 |
4 |
0.092
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
62 |
0.091
|
|
|
|
regulation of t cell mediated immunity
|
GO:0002709 |
34 |
0.091
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.091
|
|
|
|
cell cell recognition
|
GO:0009988 |
44 |
0.091
|
|
|
|
keratinocyte differentiation
|
GO:0030216 |
48 |
0.089
|
|
|
|
b cell activation involved in immune response
|
GO:0002312 |
50 |
0.089
|
|
|
|
regulation of acute inflammatory response
|
GO:0002673 |
27 |
0.089
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
61 |
0.089
|
|
|
|
positive regulation of interferon gamma production
|
GO:0032729 |
39 |
0.089
|
|
|
|
negative regulation of inflammatory response
|
GO:0050728 |
61 |
0.088
|
|
|
|
regulation of mast cell degranulation
|
GO:0043304 |
16 |
0.087
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.087
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.086
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.086
|
|
|
|
regulation of t cell costimulation
|
GO:2000523 |
2 |
0.086
|
|
|
|
dna recombination
|
GO:0006310 |
92 |
0.086
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.085
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.085
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.084
|
|
|
|
tissue remodeling
|
GO:0048771 |
102 |
0.084
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
65 |
0.084
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.083
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.083
|
|
|
|
regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903555 |
50 |
0.083
|
|
|
|
detection of stimulus
|
GO:0051606 |
84 |
0.083
|
|
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
53 |
0.081
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.081
|
|
|
|
tolerance induction to self antigen
|
GO:0002513 |
4 |
0.081
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.080
|
|
|
|
t cell lineage commitment
|
GO:0002360 |
13 |
0.080
|
|
|
|
regulation of calcium ion transport into cytosol
|
GO:0010522 |
31 |
0.080
|
|
|
|
regulation of leukocyte degranulation
|
GO:0043300 |
20 |
0.079
|
|
|
|
regulation of t cell mediated cytotoxicity
|
GO:0001914 |
18 |
0.079
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.079
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
64 |
0.078
|
|
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.078
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.078
|
|
|
|
eosinophil mediated immunity
|
GO:0002447 |
1 |
0.077
|
|
|
|
interferon gamma production
|
GO:0032609 |
67 |
0.077
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.076
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.076
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.076
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
106 |
0.076
|
|
|
|
negative regulation of eosinophil degranulation
|
GO:0043310 |
1 |
0.075
|
|
|
|
positive regulation of protein kinase b signaling
|
GO:0051897 |
32 |
0.075
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.074
|
|
|
|
interleukin 4 production
|
GO:0032633 |
24 |
0.074
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.074
|
|
|
|
telencephalon cell migration
|
GO:0022029 |
55 |
0.074
|
|
|
|
immunoglobulin production
|
GO:0002377 |
73 |
0.074
|
|
|
|
positive regulation of phospholipase c activity
|
GO:0010863 |
2 |
0.072
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
65 |
0.072
|
|
|
|
regulation of hematopoietic stem cell migration
|
GO:2000471 |
1 |
0.071
|
|
|
|
positive regulation of alpha beta t cell differentiation
|
GO:0046638 |
28 |
0.071
|
|
|
|
positive regulation of leukocyte degranulation
|
GO:0043302 |
10 |
0.071
|
|
|
|
regulation of cell projection assembly
|
GO:0060491 |
38 |
0.071
|
|
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.071
|
|
|
|
regulation of t cell anergy
|
GO:0002667 |
4 |
0.070
|
|
|
|
somatostatin signaling pathway
|
GO:0038170 |
2 |
0.070
|
|
|
|
regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014066 |
30 |
0.070
|
|
|
|
positive regulation of regulatory t cell differentiation
|
GO:0045591 |
4 |
0.069
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.069
|
|
|
|
regulation of monocyte extravasation
|
GO:2000437 |
2 |
0.069
|
|
|
|
regulation of b cell mediated immunity
|
GO:0002712 |
37 |
0.069
|
|
|
|
microglial cell activation involved in immune response
|
GO:0002282 |
1 |
0.069
|
|
|
|
positive regulation of mast cell activation involved in immune response
|
GO:0033008 |
10 |
0.068
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.068
|
Human |
|
|
microtubule based process
|
GO:0007017 |
236 |
0.068
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.068
|
|
|
|
b cell mediated immunity
|
GO:0019724 |
71 |
0.068
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.067
|
|
|
|
interleukin 1 production
|
GO:0032612 |
31 |
0.067
|
|
|
|
isotype switching to igg isotypes
|
GO:0048291 |
10 |
0.067
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.066
|
|
|
|
phosphatidylinositol 3 kinase signaling
|
GO:0014065 |
36 |
0.066
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.066
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.066
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.066
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.066
|
|
|
|
immune response inhibiting cell surface receptor signaling pathway
|
GO:0002767 |
3 |
0.066
|
|
|
|
axon ensheathment
|
GO:0008366 |
76 |
0.065
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.065
|
|
|
|
positive regulation of t cell differentiation
|
GO:0045582 |
52 |
0.065
|
|
|
|
regulation of t cell extravasation
|
GO:2000407 |
3 |
0.065
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.065
|
|
|
|
negative regulation of myeloid cell differentiation
|
GO:0045638 |
38 |
0.065
|
|
|
|
olfactory learning
|
GO:0008355 |
2 |
0.064
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.064
|
|
|
|
positive regulation of interleukin 12 production
|
GO:0032735 |
21 |
0.063
|
|
|
|
regulation of dendritic cell chemotaxis
|
GO:2000508 |
1 |
0.063
|
|
|
|
forebrain cell migration
|
GO:0021885 |
58 |
0.063
|
|
|
|
detection of abiotic stimulus
|
GO:0009582 |
60 |
0.063
|
|
|
|
granulocyte migration
|
GO:0097530 |
43 |
0.063
|
|
|
|
regulation of production of molecular mediator of immune response
|
GO:0002700 |
65 |
0.063
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.062
|
|
|
|
myeloid leukocyte migration
|
GO:0097529 |
57 |
0.062
|
|
|
|
positive regulation of antigen receptor mediated signaling pathway
|
GO:0050857 |
9 |
0.061
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
55 |
0.061
|
|
|
|
organelle assembly
|
GO:0070925 |
177 |
0.061
|
|
|
|
positive regulation of monocyte chemotaxis
|
GO:0090026 |
2 |
0.061
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.060
|
|
|
|
positive regulation of granulocyte macrophage colony stimulating factor biosynthetic process
|
GO:0045425 |
2 |
0.060
|
|
|
|
regulation of toll like receptor 2 signaling pathway
|
GO:0034135 |
3 |
0.060
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.060
|
|
|
|
regulation of phospholipase c activity
|
GO:1900274 |
3 |
0.060
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.059
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.059
|
|
|
|
positive regulation of canonical wnt signaling pathway
|
GO:0090263 |
29 |
0.059
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.059
|
|
|
|
cell recognition
|
GO:0008037 |
83 |
0.059
|
|
|
|
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002824 |
61 |
0.058
|
|
|
|
negative regulation of response to wounding
|
GO:1903035 |
77 |
0.058
|
|
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
41 |
0.058
|
|
|
|
positive regulation of lymphocyte differentiation
|
GO:0045621 |
61 |
0.058
|
|
|
|
female gamete generation
|
GO:0007292 |
74 |
0.058
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.058
|
|
|
|
cd4 positive alpha beta t cell differentiation
|
GO:0043367 |
41 |
0.057
|
|
|
|
positive regulation of chemotaxis
|
GO:0050921 |
38 |
0.057
|
|
|
|
retina development in camera type eye
|
GO:0060041 |
119 |
0.057
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.057
|
|
|
|
microglial cell activation
|
GO:0001774 |
3 |
0.057
|
|
|
|
positive regulation of myeloid leukocyte mediated immunity
|
GO:0002888 |
14 |
0.057
|
|
|
|
neutrophil chemotaxis
|
GO:0030593 |
36 |
0.057
|
|
|
|
regulation of erythrocyte differentiation
|
GO:0045646 |
23 |
0.057
|
|
|
|
regulation of cd8 positive alpha beta t cell extravasation
|
GO:2000449 |
3 |
0.056
|
|
|
|
response to reactive oxygen species
|
GO:0000302 |
56 |
0.056
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
82 |
0.056
|
|
|
|
positive regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014068 |
20 |
0.056
|
|
|
|
synapse organization
|
GO:0050808 |
125 |
0.055
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
81 |
0.055
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
81 |
0.055
|
|
|
|
platelet degranulation
|
GO:0002576 |
6 |
0.054
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
88 |
0.054
|
|
|
|
regulation of interleukin 1 beta production
|
GO:0032651 |
25 |
0.054
|
|
|
|
activation of phospholipase c activity
|
GO:0007202 |
2 |
0.054
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.054
|
|
|
|
positive regulation of isotype switching to igg isotypes
|
GO:0048304 |
7 |
0.054
|
|
|
|
gamma delta t cell activation
|
GO:0046629 |
13 |
0.054
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.053
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
128 |
0.053
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.053
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.053
|
|
|
|
zymogen activation
|
GO:0031638 |
41 |
0.052
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
86 |
0.052
|
|
|
|
transition metal ion homeostasis
|
GO:0055076 |
54 |
0.051
|
|
|
|
regulation of protein kinase b signaling
|
GO:0051896 |
56 |
0.051
|
|
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
45 |
0.051
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.050
|
|
|
|
negative regulation of toll like receptor 2 signaling pathway
|
GO:0034136 |
3 |
0.050
|
|
|
|
blastocyst growth
|
GO:0001832 |
23 |
0.050
|
|
|
|
platelet activation
|
GO:0030168 |
40 |
0.050
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.050
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.049
|
|
|
|
regulation of hypersensitivity
|
GO:0002883 |
10 |
0.049
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.049
|
Human |
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.049
|
|
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.048
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.048
|
|
|
|
regulation of gamma delta t cell activation
|
GO:0046643 |
9 |
0.048
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.048
|
|
|
|
regulation of regulated secretory pathway
|
GO:1903305 |
20 |
0.048
|
|
|
|
interleukin 2 production
|
GO:0032623 |
33 |
0.048
|
|
|
|
regulation of platelet activation
|
GO:0010543 |
17 |
0.048
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.047
|
|
|
|
b cell apoptotic process
|
GO:0001783 |
19 |
0.047
|
|
|
|
positive regulation of response to wounding
|
GO:1903036 |
66 |
0.047
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
46 |
0.047
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.047
|
|
|
|
zinc ion homeostasis
|
GO:0055069 |
10 |
0.047
|
|
|
|
long term memory
|
GO:0007616 |
15 |
0.047
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
39 |
0.046
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.046
|
|
|
|
dendrite development
|
GO:0016358 |
115 |
0.046
|
|
|
|
regulation of cell division
|
GO:0051302 |
76 |
0.046
|
|
|
|
lymphocyte apoptotic process
|
GO:0070227 |
54 |
0.046
|
|
|
|
positive regulation of acute inflammatory response
|
GO:0002675 |
16 |
0.046
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.046
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.046
|
|
|
|
b cell homeostasis
|
GO:0001782 |
34 |
0.046
|
|
|
|
hair follicle development
|
GO:0001942 |
85 |
0.046
|
|
|
|
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger
|
GO:0007187 |
55 |
0.045
|
|
|
|
negative regulation of interleukin 2 biosynthetic process
|
GO:0045085 |
3 |
0.045
|
|
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.045
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.045
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
47 |
0.045
|
|
|
|
negative regulation of interleukin 5 production
|
GO:0032714 |
4 |
0.045
|
|
|
|
regulation of glial cell differentiation
|
GO:0045685 |
41 |
0.044
|
|
|
|
positive regulation of gliogenesis
|
GO:0014015 |
27 |
0.044
|
|
|
|
tumor necrosis factor production
|
GO:0032640 |
50 |
0.044
|
|
|
|
gamma delta t cell differentiation
|
GO:0042492 |
11 |
0.044
|
|
|
|
positive regulation of muscle contraction
|
GO:0045933 |
10 |
0.043
|
|
|
|
cellular zinc ion homeostasis
|
GO:0006882 |
9 |
0.043
|
|
|
|
defense response to gram positive bacterium
|
GO:0050830 |
50 |
0.043
|
|
|
|
endodermal cell fate specification
|
GO:0001714 |
4 |
0.043
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.043
|
|
|
|
sensory perception of pain
|
GO:0019233 |
47 |
0.043
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.043
|
|
|
|
cytosolic calcium ion transport
|
GO:0060401 |
48 |
0.043
|
|
|
|
positive regulation of interleukin 2 biosynthetic process
|
GO:0045086 |
8 |
0.043
|
|
|
|
regulation of immunoglobulin mediated immune response
|
GO:0002889 |
37 |
0.043
|
|
|
|
regulation of immunological synapse formation
|
GO:2000520 |
2 |
0.042
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.042
|
|
|
|
t cell extravasation
|
GO:0072683 |
4 |
0.042
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.042
|
|
|
|
positive regulation of interferon alpha production
|
GO:0032727 |
4 |
0.042
|
|
|
|
granulocyte chemotaxis
|
GO:0071621 |
39 |
0.042
|
|
|
|
interleukin 12 secretion
|
GO:0072610 |
3 |
0.042
|
|
|
|
positive regulation of cd4 positive alpha beta t cell differentiation
|
GO:0043372 |
14 |
0.042
|
|
|
|
regulation of lymphocyte anergy
|
GO:0002911 |
4 |
0.042
|
|
|
|
cellularization
|
GO:0007349 |
1 |
0.041
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.041
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
45 |
0.041
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.041
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.041
|
|
|
|
platelet aggregation
|
GO:0070527 |
20 |
0.040
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.040
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.040
|
|
|
|
fc receptor mediated inhibitory signaling pathway
|
GO:0002774 |
1 |
0.040
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.040
|
|
|
|
response to metal ion
|
GO:0010038 |
47 |
0.040
|
|
|
|
regulation of isotype switching to igg isotypes
|
GO:0048302 |
10 |
0.039
|
|
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
49 |
0.039
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
84 |
0.039
|
|
|
|
immune complex clearance by monocytes and macrophages
|
GO:0002436 |
2 |
0.038
|
|
